NAKA Hiroyuki 中宏之

Researcher Number	40281761
External Links
Affiliation (based on the past Project Information) *help	2003 – 2004: 奈良県立医科大学, 医学部, 助手 2002: Nara Medical University, Pediatrics, Research Associate, 小児科, 助手 2001 – 2002: 奈良県立医科大学, 小児科学教室, 助手 1996 – 2001: 奈良県立医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Pediatrics Except Principal Investigator Pediatrics / Hematology / General surgery / Hematology
Keywords	Principal Investigator Lentivirus / Adenovirus / Gene Therapy / Hemophilia A / レンチウィルスベクター / アデノウィルスベクター / レンチウィルス / アデノウィルス / 遺伝子治療 / 血友病A / Hypoprothrombinemia / 先天性プロトロンビン欠乏症 … More Except Principal Investigator … More フローチャンバー / 遺伝子治療 / 第VIII因子 / platelet thrombus formation / flow chamber / von Willebrand factor / 血小板血栓形成 / フォンヴィレブランド因子 / VWF-cleaving protease / thrombophilia / factor VIII / Regenerative medicine / Gene therapy / Extracellular matrix / Liver diseases / Tissue engineering / Hepatocyte transplantation / レンテウィルスベクター / ティッシュエンジニアリング / 再生医学 / 細胞外マトリックス / 肝疾患 / 組織工学 / 肝細胞移植 / confocal microscopy / physiologic blood flow / blood coagulation / 血小板 / 共焦点顕微鏡 / 生理的血流 / 血液凝固 / Shear rate / Blood How / Thrombus formation / Integrin / Glycoprotein Ib / 血小板膜タンパクIb / on Willebrand因子 / ずり速度 / 血流 / 血栓形成 / インテグリン / 血小板膜蛋白Ib / von Willebrand因子 / MAMMALS / FACTOR VIII / 哺乳動物 / von Willebrand disease / platelet glycoprotein Ib / 血小板膜糖蛋白 Ib / 血小板インテグリン / フォンヴィレブランド病 / 血小板膜糖蛋白Ib / factor VIII gene / inhibitor / anti factor VIII alloantibody / hemophilia A / 同種抗体 / C2ドメイン / 第VIIII因子遺伝子 / インヒビター / 抗第VIII因子同種抗体 / 血友病A / children / Upshaw-Schulman Syndome / Heparin cofactor-II / protein S / protein C / antithrombin / APCレジスタンス / アンチトロンビンIII / 溶血性尿毒症症候群 / von Willebrand factor (vWF) / Upshaw-Schulman症侯群 / 小児 / vWF-cleaving protease / Upshaw-Schulman症候群 / ヘパリンコファクターII / プロテインS / プロテインC / アンチトロンビン / gene therapy / subunit / cross-reactivity / 血友病犬 / イヌ第四因子 / ヒト第四因子 / 遺伝子発現 / サブユニット Less

Clarification of mechanisms for thrombus formation under physiologic blood flow
- Principal Investigator
  
  SUGIMOTO Mitsuhiko
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Nara Medical University
Engineering a liver tissue into subcutaneous space
- Principal Investigator
  
  NAKAJIMA Yoshiyuki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Nara Medical University
Analysis of shear-dependent functions of von Willebrand factor under physiologic blood flow conditions
- Principal Investigator
  
  SUGIMOTO Mitsuhiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nara Medical University
THE EVOLUTION OF BLOOD COAGULATION FACTOR VIII IN MAMMALS
- Principal Investigator
  
  TANAKA Ichiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  NARA MEDICAL UNIVERSITY
Hemophilia A gene therapy using Adenovirus vector (Mouse model)Principal Investigator
- Principal Investigator
  
  NAKA Hiroyuki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Department of Pediatrics, Nara Medical University
Analysis of structure-function relationships of von Willebrand factor in thrombus formation under flow
- Principal Investigator
  
  SUGIMOTO Mitsuhiko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nara Medical University
Clinical and Biomolecular Studies on Thrombophilia in Children.
- Principal Investigator
  
  YOSHIOKA Akira
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Nara Medical University
Study about factor VIII expression and immunological influence in the gene therapy of hemophilia A
- Principal Investigator
  
  SHIMA Midori
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nara Medical University
The gene analysis of congenital hypoprothrombinemiaPrincipal Investigator
- Principal Investigator
  
  NAKA Hiroyuki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nara Medical University
A FUNDAMENTAL RESEARCH FOR GENE THERAPY OF HEMOPHILIA A-EXPRESSION AND RECONSTITUTION OF FACTOR VIII SUBUNITS-
- Principal Investigator
  
  TANAKA Ichiro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  NARA MEDICAL UNIVERSITY

All 2006 2005 2004

All Journal Article Book

[Book] 肝ティッシユエンジニアリングによる次世代療法の確立にむけて(分子細胞治療)2005
- Author(s)
  大橋一夫, 中島祥介
- Total Pages
  103
- Publisher
  先端医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390382
[Book] 分子細胞治療2005
- Author(s)
  大橋一夫, 中島洋介
- Total Pages
  103
- Publisher
  肝ティッシュエンジニアリングによる次世代療法の確立にむけて
- Data Source
  KAKENHI-PROJECT-15390382
[Journal Article] Plasma ADAMTS13 activity may predict early adverse events in living donor liver transplantation2006
- Author(s)
  Ko S, Nakajima Y, et al.
- Journal Title
  
  Liver Transplantation On-line(In press)
- Data Source
  KAKENHI-PROJECT-15390382
[Journal Article] Genetic modification of hepatocytes towards hepatocyte transplantation and liver tissue engineering2006
- Author(s)
  Kuge H, Ohashi K, Nakajima Y, et al.
- Journal Title
  
  Cell Transplantation (In press)
- Data Source
  KAKENHI-PROJECT-15390382
[Journal Article] In vivo engineering of metaolically active hepatic tissues in a neovascularized subcutaneous cavity.2006
- Author(s)
  Yokoyama T, Ohashi K, Nakajima Y, et al.
- Journal Title
  
  Am J Transplantation 6(1)
  
  Pages: 50-59
- Data Source
  KAKENHI-PROJECT-15390382
[Journal Article] Liver tissue engineering at extra-hepatic sites in mice as a potential new therapy for genetic liver diseases.2005
- Author(s)
  Ohashi K, Nakajima Y, et al.
- Journal Title
  
  Hepatology 41(1)
  
  Pages: 132-140
- Data Source
  KAKENHI-PROJECT-15390382
[Journal Article] Stability and repeat regeneration potential of the engineered liver tissues under the kidney capsule in mice.2005
- Author(s)
  Ohashi K, Nakajima Y, et al.
- Journal Title
  
  Cell Transplantation 14(9)
  
  Pages: 621-627
- Data Source
  KAKENHI-PROJECT-15390382
[Journal Article] Heterotopically transplanted hepatocyte survival depends on extracellular matrix components.2005
- Author(s)
  Ohashi K, Nakajima Y, et al.
- Journal Title
  
  Transplantation Proceedings 37(10)
  
  Pages: 4587-4588
- Data Source
  KAKENHI-PROJECT-15390382
[Journal Article] 肝細胞移植の現況と展望:血友病の次世代治療の確立にむけて2004
- Author(s)
  大橋一夫, 中島祥介
- Journal Title
  
  日本血栓止血学会雑誌 15:6
  
  Pages: 541-546
- NAID
  10016757546
- Data Source
  KAKENHI-PROJECT-15390382

1. TANAKA Ichiro (00201616)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. SUGIMOTO Mitsuhiko (80192128)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. YOSHIOKA Akira (40106498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TAKAHASHI Yukihiro (60142379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TAKAMIYA Osamu (50216785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SHIMA Midori (30162663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NOGAMI Keiji (50326328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NAKAJIMA Yoshiyuki (00142381)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
9. OHASHI Kazuo (40364062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
10. 朴永東 (10285364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAKA Hiroyuki 中 宏之

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Hemophilia A gene therapy using Adenovirus vector (Mouse model)Principal Investigator

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The gene analysis of congenital hypoprothrombinemiaPrincipal Investigator

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[Book] 肝ティッシユエンジニアリングによる次世代療法の確立にむけて(分子細胞治療)2005

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[Book] 分子細胞治療2005

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Total Pages

Publisher

Data Source

[Journal Article] Plasma ADAMTS13 activity may predict early adverse events in living donor liver transplantation2006

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[Journal Article] Genetic modification of hepatocytes towards hepatocyte transplantation and liver tissue engineering2006

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[Journal Article] In vivo engineering of metaolically active hepatic tissues in a neovascularized subcutaneous cavity.2006

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[Journal Article] Liver tissue engineering at extra-hepatic sites in mice as a potential new therapy for genetic liver diseases.2005

NAKA Hiroyuki 中宏之