Masumura Kenichi 増村健一

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MASUMURA Kenichi 増村健一

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Researcher Number	40291116
Other IDs
Affiliation (Current)	2025: 国立医薬品食品衛生研究所, 安全性予測評価部, 部長
Affiliation (based on the past Project Information) *help	2022 – 2023: 国立医薬品食品衛生研究所, 安全性予測評価部, 部長 2011 – 2021: 国立医薬品食品衛生研究所, 変異遺伝部, 室長 2010: 国立医薬品食品衛生研究所, 主任研究官 2005 – 2009: National Institute of Health Sciences, Division of Genetics and Mutagenesis, Chief Researcher, 変異遺伝部, 主任研究官 2006: 医薬品食品衛生研, 研究員 2004: 国立医薬品食品衛生研究所, 変異遺伝部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 63030:Chemical substance influence on environment-related / Risk sciences of radiation and chemicals / Risk sciences of radiation/Chemicals Except Principal Investigator Risk sciences of radiation/Chemicals / Basic Section 63030:Chemical substance influence on environment-related / Risk sciences of radiation and chemicals / 食の安全 / Environmental and hygienic pharmacy
Keywords	Principal Investigator 生殖細胞突然変異 / 遺伝子突然変異 / 次世代影響 / ゲノム / 遺伝毒性 / DNA付加体 / アクリルアミド / DNA損傷 / 生殖細胞 / トランスジェニックマウス遺伝子突然変異試験 / 次世代シークエンサー / 環境変異原 … More Except Principal Investigator … More 突然変異 / 遺伝毒性 / ＤＮＡ修復 / 転写 / 8-oxoguanine / DNA損傷 / 環境 / 遺伝子 / 遺伝子発現 / 免疫 / DNA修復 / strain difference / preneoplastic lesion / oxidative stress / gene mutation / gpt delta rat / endogenous carcinogenesis / choline-deficient L-amino acid-defined diet / エピジェネティック発がん機構 / GST-P陽性前がん病変 / gpt deltaトランスジェニックラット / 体細胞突然変異 / 系統差 / 前がん病変 / 酸化性ストレス / 遺伝子突然変異 / gpt deltaラット / 内因性発がん / コリン欠乏アミノ酸食 / 変異原性 / 規制効果 / 肺がん / in vivoアッセイ / リスク評価 / 環境変異原物質 / 大気汚染物質 / DNAポリメラーゼζ / トランスリージョンDNA合成 / 遺伝毒性発がん物質 / 閾値 / 癌 / 有害化学物質 / 遺伝毒性の閾値 / トキシコロジー Less

遺伝情報発現と遺伝子突然変異の相関
- Principal Investigator
  
  堀端克良
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  National Institute of Health Sciences
A study on DNA damages in germ cells of male mice and germline mutations induced in the offspringPrincipal Investigator
- Principal Investigator
  
  増村健一
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  National Institute of Health Sciences
Analysis of mutagenesis relating to DNA topology, transcription and DNA repair
- Principal Investigator
  
  Horibata Katsuyoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  National Institute of Health Sciences
Studies on quantitative evaluation of inherited germline mutationsPrincipal Investigator
- Principal Investigator
  
  Masumura Kenichi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  National Institute of Health Sciences
Assessment of current lung cancer and related health risk by past-exposure of particulates suspended in air
- Principal Investigator
  
  Aoki Yasunobu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  National Institute for Environmental Studies
Studies on mechanisms underlying genotoxic thresholds through genetic modification of DNA polymerase zeta
- Principal Investigator
  
  NOHMI Takehiko
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  National Institute of Health Sciences
Studies on roles of translesion DNA synthesis in thresholds for genotoxic substances
- Principal Investigator
  
  NOUMI Takehiko
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  National Institute of Health Sciences
1分子PCR法を用いた次世代遺伝毒性試験法の開発Principal Investigator
- Principal Investigator
  
  増村健一
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  National Institute of Health Sciences
Study on the Mechanisms Underlying Endogenous Hepatocarcinogenesis Induced Only by the Manipulation of Food Composition
- Principal Investigator
  
  NAKAE Dai
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  食の安全
- Research Institution
  Sasaki Institute, Sasaki Foundation

[Book] 衛生試験法・注解2020，1.3 遺伝毒性試験法 p135-1672020
- Author(s)
  増村健一（分担執筆者）（（公社）日本薬学会編）
- Total Pages
  1348
- Publisher
  金原出版（株）
- ISBN
  9784307470490
- Data Source
  KAKENHI-PROJECT-19K12347
[Book] 第9版食品添加物公定書解説書2019
- Author(s)
  増村健一（分担執筆者）（監修：川西、穐山、河村、佐藤）
- Total Pages
  3200
- Publisher
  廣川書店（株）
- ISBN
  9784567018548
- Data Source
  KAKENHI-PROJECT-19K12347
[Book] 衛生試験法・注解20152015
- Author(s)
  増村健一
- Total Pages
  1300
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-25293034
[Book] 衛生試験法・注解2015，1.3 遺伝毒性試験法，1.3.3げっ歯類を用いる試験，(2)トランスジェニック動物遺伝子突然変異試験2015
- Author(s)
  増村健一
- Total Pages
  1300
- Publisher
  （公社）日本薬学会編，金原出版（株）
- Data Source
  KAKENHI-PROJECT-25281027
[Journal Article] Genome-wide direct quantification of in vivo mutagenesis using high-accuracy paired-end and complementary consensus sequencing2023
- Author(s)
 You Xinyue、Cao Yiyi、Suzuki Takayoshi、Shao Jie、Zhu Benzhan、Masumura Kenichi、Xi Jing、Liu Weiying、Zhang Xinyu、Luan Yang
- Journal Title
 
 Nucleic Acids Research
 
 Volume: 51 Issue: 21 Pages: e109-e109
- DOI
 10.1093/nar/gkad909
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-19K12347
[Journal Article] Derivation of human health hazard assessment values of 1,2-dichloroethane under the Japan Chemical Substances Control Law2023
- Author(s)
  Kawashima Akira、Inoue Kaoru、Ushida Kazuo、Kai Kaoru、Suzuki Hiroshi、Yoshida-Yamashita Lucia Satiko、Hirose Akihiko、Masumura Kenichi
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume: 10 Issue: 3 Pages: 91-103
- DOI
  10.2131/fts.10.91
- ISSN
  2189-115X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12347
[Journal Article] In vivo genotoxicity testing strategies: Report from the 8th International Workshop on Genotoxicity Testing (<scp>IWGT</scp>)2023
- Author(s)
 Beevers Carol、Uno Yoshifumi、Meurer Krista、Hamada Shuichi、Hashimoto Kiyohiro、Kirkland David、LeBaron Matthew J.、Le Curieux Frank、Le Hegarat Ludovic、Martus Hans‐Joerg、Masumura Kenichi、Ohyama Wakako、Roberts Daniel J.、Vasquez Marie、Whitwell James、Witt Kristine L.
- Journal Title
 
 Environmental and Molecular Mutagenesis
 
 Volume: -
- DOI
 10.1002/em.22578
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-19K12347
[Journal Article] In vivo mutagenicity assessment of orally treated tert-butyl hydroperoxide in the liver and glandular stomach of MutaMouse2023
- Author(s)
  Murata Yasumasa、Suzuki Kenichiro、Shigeta Yoshiyuki、Iso Takako、Hirose Nozomu、Umano Takaaki、Horibata Katsuyoshi、Sugiyama Kei-ichi、Hirose Akihiko、Masumura Kenichi、Matsumoto Mariko
- Journal Title
  
  Genes and Environment
  
  Volume: 45 Issue: 1
- DOI
  10.1186/s41021-023-00285-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12347
[Journal Article] In vivo mutagenicity assessment of styrene in MutaMouse liver and lung2023
- Author(s)
  Murata Yasumasa、Natsume Masakatsu、Iso Takako、Shigeta Yoshiyuki、Hirose Nozomu、Umano Takaaki、Horibata Katsuyoshi、Sugiyama Kei-ichi、Masumura Kenichi、Hirose Akihiko、Matsumoto Mariko
- Journal Title
  
  Genes and Environment
  
  Volume: 45 Issue: 1 Pages: 12-12
- DOI
  10.1186/s41021-023-00270-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12189, KAKENHI-PROJECT-19K12347
[Journal Article] New trend in genotoxicity research taking into account genome instability2022
- Author(s)
  Sugiyama K, Masumura K
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 157 Issue: 4 Pages: 265-270
- DOI
  10.1254/fpj.22015
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-19K12347
[Journal Article] Derivation of human health hazard assessment values for toluene under the Japanese Chemical Substances Control Law2022
- Author(s)
  Kawashima A, Inoue K, Ushida K, Kai K, Suzuki H, Matsumoto M, Masumura K, Hirose A
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume: 9 Issue: 4 Pages: 123-133
- DOI
  10.2131/fts.9.123
- ISSN
  2189-115X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12347
[Journal Article] Absence of in vivo mutagenicity of 4,4'-oxybis(benzenesulfonohydrazide) in liver and glandular stomach of MutaTM Mouse2022
- Author(s)
 Iso T, Natsume M, Murata Y, Shigeta Y, Hirose N, Umano T, Horibata K, Masumura K, Sugiyama K, Matsumoto M, Hirose A
- Journal Title
 
 Fundamental Toxicological Sciences
 
 Volume: 9 Issue: 2 Pages: 31-36
- DOI
 10.2131/fts.9.31
- ISSN
 2189-115X
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-19K12347
[Journal Article] Summary information of human health hazard assessment of existing chemical substances (VIII).2022
- Author(s)
  Murata Y, Umano T, Iso T, Shigeta Y, Hirose N, Inoue K, Yamada T, Masumura K, Matsumoto M
- Journal Title
  
  Bull. Natl Inst. Haelth Sci
  
  Volume: 140 Pages: 54-60
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12347
[Journal Article] Genotoxicity assessment of food-flavoring chemicals used in Japan2022
- Author(s)
  Honma M, Yamada M, Yasui M, Horibata K, Sugiyama K, Masumura K
- Journal Title
  
  Toxicology Reports
  
  Volume: 9 Pages: 1008-1012
- DOI
  10.1016/j.toxrep.2022.04.026
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12347
[Journal Article] In vivo and in vitro mutagenicity of perillaldehyde and cinnamaldehyde2021
- Author(s)
  Honma Masamitsu、Yamada Masami、Yasui Manabu、Horibata Katsuyoshi、Sugiyama Kei-ichi、Masumura Kenichi
- Journal Title
  
  Genes and Environment
  
  Volume: 43 Issue: 1 Pages: 30-30
- DOI
  10.1186/s41021-021-00204-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12347
[Journal Article] New homozygous gpt delta transgenic rat strain improves an efficiency of the in vivo mutagenicity assay2021
- Author(s)
  Masumura Kenichi、Ando Tomoko、Ukai Akiko、Fujiwara Sho、Yokose Shigeo、You Xinyue、Suzuki Takayoshi、Hayashi Hiroyuki、Nohmi Takehiko、Takagi Hisayoshi、Honma Masamitsu
- Journal Title
  
  Genes and Environment
  
  Volume: 43 Issue: 1 Pages: 25-25
- DOI
  10.1186/s41021-021-00195-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12347
[Journal Article] Comparison of the frequencies of ENU-induced point mutations in male germ cells and inherited germline mutations in their offspring2021
- Author(s)
  Masumura Kenichi、Ando Tomoko、Toyoda-Hokaiwado Naomi、Ukai Akiko、Nohmi Takehiko、Honma Masamitsu
- Journal Title
  
  Genes and Environment
  
  Volume: 43 Issue: 1 Pages: 43-43
- DOI
  10.1186/s41021-021-00216-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12347
[Journal Article] Characteristic mutations induced in the small intestine of Msh2-knockout gpt delta mice2021
- Author(s)
  Aoki Yasunobu、Ohno Mizuki、Matsumoto Michiyo、Matsumoto Michi、Masumura Kenichi、Nohmi Takehiko、Tsuzuki Teruhisa
- Journal Title
  
  Genes and Environment
  
  Volume: 43 Issue: 1 Pages: 27-27
- DOI
  10.1186/s41021-021-00196-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03254, KAKENHI-PROJECT-19K12347
[Journal Article] Effect of sampling time on somatic and germ cell mutations induced by acrylamide in gpt delta mice2021
- Author(s)
  Hagio S, Tsuji N, Furukawa S, Takeuchi K, Hayashi S, Kuroda Y, Honma M, Masumura K.
- Journal Title
  
  Genes and Environ
  
  Volume: 43 Issue: 1 Pages: 4-4
- DOI
  10.1186/s41021-021-00175-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12347
[Journal Article] Development of a new quantitative structure?activity relationship model for predicting Ames mutagenicity of food flavor chemicals using StarDrop? auto-Modeller?2021
- Author(s)
  Kasamatsu Toshio、Kitazawa Airi、Tajima Sumie、Kaneko Masahiro、Sugiyama Kei-ichi、Yamada Masami、Yasui Manabu、Masumura Kenichi、Horibata Katsuyoshi、Honma Masamitsu
- Journal Title
  
  Genes and Environment
  
  Volume: 43 Issue: 1 Pages: 16-16
- DOI
  10.1186/s41021-021-00182-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12347
[Journal Article] Oxidative-stress-driven in vivo mutagenesis induced by oral administration of potassium bromate in the small intestines of gpt delta mice2020
- Author(s)
  Aoki Y, Taniguchi Y, Matsumoto M, Matsumoto M, Ohno M, Masumura K, Sasaki S, Tsuzuki T, Yamamoto M, Nohmi T
- Journal Title
  
  Mutation Reseaｒch
  
  Volume: 850-851 Pages: 503136-503136
- DOI
  10.1016/j.mrgentox.2020.503136
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12347, KAKENHI-PROJECT-17K19494, KAKENHI-PROJECT-20H03254
[Journal Article] Mutant Frequency is not Increased in Mice Orally Exposed to Sodium Dichromate2019
- Author(s)
  Aoki Y., Matsumoto M., Matsumoto M., Masumura K., Nohmi T.
- Journal Title
  
  Food Safety
  
  Volume: 7 Issue: 1 Pages: 2-10
- DOI
  10.14252/foodsafetyfscj.2018014
- NAID
  130007627483
- ISSN
  2187-8404
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05109, KAKENHI-PROJECT-19K12347
[Journal Article] Targets and mechanisms of chemically induced aneuploidy. Part 1 of the report of the 2017 IWGT workgroup on assessing the risk of aneugens for carcinogenesis and hereditary diseases2019
- Author(s)
  Lynch AM, Eastmond D, Elhajouji A, Froetschl R, Kirsch-Volders M, Marchetti F, Masumura K, Pacchierotti F, Schuler M, Tweats D
- Journal Title
  
  Mutation Reseaｒch
  
  Volume: 847 Pages: 403025-403025
- DOI
  10.1016/j.mrgentox.2019.02.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12347
[Journal Article] Chemically induced aneuploidy in germ cells. Part II of the report of the 2017 IWGT workgroup on assessing the risk of aneugens for carcinogenesis and hereditary diseases2019
- Author(s)
  Pacchierotti F, Masumura K, Eastmond D, Elhajouji A, Froetschl R, Kirsch-Volders M, Lynch AM, Schuler M, Tweats D
- Journal Title
  
  Mutation Reseaｒch
  
  Volume: 848 Pages: 403023-403023
- DOI
  10.1016/j.mrgentox.2019.02.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12347
[Journal Article] Role of aneuploidy in the carcinogenic process: Part 3 of the report of the 2017 IWGT workgroup on assessing the risk of aneugens for carcinogenesis and hereditary diseases2019
- Author(s)
  Tweats D, Eastmond DA, Lynch AM, Elhajouji A, Froetschl R, Kirsch-Volders M, Marchetti F, Masumura K, Pacchierotti F, Schuler M
- Journal Title
  
  Mutation Reseaｒch
  
  Volume: 847 Pages: 403032-403032
- DOI
  10.1016/j.mrgentox.2019.03.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12347
[Journal Article] Multiple-endpoint genotoxicity assay for colon carcinogen 1,2-dimethylhydrazine2019
- Author(s)
  Hori H, Shimoyoshi S, Tanaka S, Momonami A, Masumura K, Yamada M, Fujii W, Kitagawa Y, Hayashi M
- Journal Title
  
  Mutation Reseaｒch
  
  Volume: 849 Pages: 503130-503130
- DOI
  10.1016/j.mrgentox.2019.503130
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12347
[Journal Article] Transgenic rat models for mutagenesis and carcinogenesis2017
- Author(s)
  Nohmi T, Masumura K, Toyoda-Hokaiwado N.
- Journal Title
  
  Genes and Environment
  
  Volume: 39 Issue: 1 Pages: 11-11
- DOI
  10.1186/s41021-016-0072-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25281027, KAKENHI-PROJECT-26281029
[Journal Article] Evaluation of the sensitivity and specificity of in vivo erythrocyte micronucleus and transgenic rodent gene mutation tests to detect rodent carcinogens2016
- Author(s)
  Morita T , Hamada S, Masumura K, Wakata A, Maniwa J, Takasawa H, Yasunaga K, Hashizume, T, Honma M.
- Journal Title
  
  Mutation Research
  
  Volume: 802 Pages: 1-29
- DOI
  10.1016/j.mrgentox.2016.03.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25281027
[Journal Article] Dose-dependent de novo germline mutations detected by whole-exome sequencing in progeny of ENU-treated male gpt delta mice.2016
- Author(s)
  Masumura K,Toyoda-Hokaiwado N, Ukai A, Gondo Y, Honma M, Nohmi T
- Journal Title
  
  Mutation Research
  
  Volume: 810 Pages: 30-39
- DOI
  10.1016/j.mrgentox.2016.09.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25241016, KAKENHI-PROJECT-25281027
[Journal Article] Estimation of the frequency of inherited germline mutations by whole exome sequencing in ethyl nitrosourea-treated and untreated gpt delta mice.2016
- Author(s)
  Masumura K, Toyoda-Hokaiwado N, Ukai A, Gondo Y, Honma M, Nohmi T
- Journal Title
  
  Genes and Environment
  
  Volume: 38 Issue: 1 Pages: 10-10
- DOI
  10.1186/s41021-016-0035-y
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25241016, KAKENHI-PROJECT-25281027
[Journal Article] Alterations in the mutagenicity and mutation spectrum induced by benzo[a]pyrene instilled in the lungs of gpt delta mice of various ages2015
- Author(s)
  Aoki Y, Akiko A, Sugawara Y, Hiyoshi-Arai K, Goto S, Masumura K, Nohmi T.
- Journal Title
  
  Genes and Environment
  
  Volume: 37 Issue: 1 Pages: 7-7
- DOI
  10.1186/s41021-015-0004-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25281027, KAKENHI-PROJECT-25293034
[Journal Article] Genomic integration of lambda EG10 transgene in gpt delta transgenic rodents2015
- Author(s)
  Masumura K, Sakamoto Y, Kumita W, Honma M, Nishikawa A, Nohmi T.
- Journal Title
  
  Genes and Environment
  
  Volume: 37 Issue: 1 Pages: 24-24
- DOI
  10.1186/s41021-015-0024-6
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25281027, KAKENHI-PROJECT-25293034, KAKENHI-PROJECT-26281029
[Journal Article] Role of p53 in the progression from ochratoxin A-induced DNA damage to gene　mutations in the kidneys of mice.2015
- Author(s)
  Kuroda K, Hibi D, Ishii Y, Yokoo Y, Takasu S, Kijima A, Matsushita K, Masumura K, Kodama Y, Yanai T, Sakai H, Nohmi T, Ogawa K, Umemura T.
- Journal Title
  
  Toxicol Sci.
  
  Volume: 144 Issue: 1 Pages: 65-76
- DOI
  10.1093/toxsci/kfu267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25281027
[Journal Article] Alterations in the mutagenicity and mutation spectrum induced by benzo[a]pyrene instilled in the lungs of gpt delta mice of various ages.2015
- Author(s)
  Aoki Y, Hashimoto A, Sugawara Y, Hiyoshi-Arai K, Goto S, Masumura K, Nohmi T.
- Journal Title
  
  Genes and Environment.
  
  Volume: 37
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293034
[Journal Article] Genotoxicity of phenacetin in the kidney and liver of Sprague-Dawley gpt delta transgenic rats in 26-week and 52-week repeated-dose studies.2014
- Author(s)
  Kawamura Y, Hayashi H, Masumura K, Numazawa S, Nohmi T.
- Journal Title
  
  Toxicology
  
  Volume: 324 Pages: 10-17
- DOI
  10.1016/j.tox.2014.07.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25281027, KAKENHI-PROJECT-25293034
[Journal Article] Ochratoxin A induces DNA double-strand breaks and large deletion mutations in the carcinogenic target site of gpt delta rats2014
- Author(s)
  K. Kuroda, D. Hibi, Y. Ishii, S. Takasu, A. Kijima, K. Matsushita, K. Masumura, M. Watanabe, Y. Sugita-Konishi, H. Sakai, T. Yanai, T. Nohmi, K. Ogawa and T. Umemura
- Journal Title
  
  Mutagenesis
  
  Volume: 29 Issue: 1 Pages: 27-36
- DOI
  10.1093/mutage/get054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241016, KAKENHI-PROJECT-25281027
[Journal Article] In vivo evidence that DNA polymerase kappa is responsible for error-free bypass across DNA cross-links induced by mitomycin C.2014
- Author(s)
  Takeiri A, Wada NA, Motoyama S, Matsuzaki K, Tateishi H, Matsumoto K, Niimi N, Sassa A, Grúz P, Masumura K, Yamada M, Mishima M, Jishage KI, Nohmi T.
- Journal Title
  
  DNA Repair
  
  Volume: 24 Pages: 113-121
- DOI
  10.1016/j.dnarep.2014.09.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25281027, KAKENHI-PROJECT-25293034
[Journal Article] Evaluation of in vivo genotoxicity induced by N-ethyl-N-nitrosourea, benzo[a]pyrene, and 4-nitroquinoline-1-oxide in the Pig-a and gpt assays2013
- Author(s)
  K. Horibata, A. Ukai, T. Kimoto, T. Suzuki, N. Kamoshita, K. Masumura, T. Nohmi and M. Honma
- Journal Title
  
  Environ. Mol. Mutagen.
  
  Volume: 54 Issue: 9 Pages: 747-754
- DOI
  10.1002/em.21818
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241016, KAKENHI-PROJECT-25281027
[Journal Article] Evaluation of the genotoxicity of tamoxifen in the liver and kidney of F344 gpt delta transgenic rat in 3-week and 13-week repeated dose studies2013
- Author(s)
  Y. Kawamura, H. Hayashi, Y. Kurata, K. Hirasuka, K. Masumura and T. Nohmi
- Journal Title
  
  Toxicol.
  
  Volume: 312 Pages: 56-62
- DOI
  10.1016/j.tox.2013.07.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241016, KAKENHI-PROJECT-25281027
[Journal Article] 2nd International Symposium on Genotoxic and Carcinogenic Thresholds2012
- Author(s)
  T. Nohmi, M. Honma, M. Yamada, K. Masumura, M. Yasui, K. Horibata and S. Fukushima
- Journal Title
  
  Genes and Environment
  
  Volume: 34 Issue: 4 Pages: 141-145
- DOI
  10.3123/jemsge.34.141
- NAID
  10031125861
- ISSN
  1880-7046, 1880-7062
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241016
[Journal Article] in vivo Approaches to Identify Mutations and in vitro Research to Reveal Underlying Mechanisms of Genotoxic Thresholds2012
- Author(s)
 T. Nohmi, M. Yamada and K. Masumura
- Journal Title
 
 Genes and Environment
 
 Volume: 34 Issue: 4 Pages: 146-152
- DOI
 10.3123/jemsge.34.146
- NAID
 10031125862
- ISSN
 1880-7046, 1880-7062
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-22241016
[Journal Article] Antigenotoxic effects of p53 on spontaneous and ultraviolet light B-induced deletions in the epidermis of gpt delta transgenic mice2011
- Author(s)
  K. Masumura
- Journal Title
  
  Environ. Mol. Mutagen.
  
  Volume: 52 Issue: 3 Pages: 244-252
- DOI
  10.1002/em.20610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241016
[Journal Article] Integration of in vivo genotoxicity and short-term carcinogenicity assays using F344 gpt delta transgenic rats : in vivo mutagenicity of 2,4-diaminotoluene and 2,6-diaminotoluene structural isomers2010
- Author(s)
  N Toyoda-Hokaiwado, T. Inoue, K. Masumura, H. Hayashi, Y. Kawamura, Y. Kurata, M. Takamune, M. Yamada, H. Sanada, T. Umemura, A. Nishikawa and T. Nohmi
- Journal Title
  
  Toxicol. Sci.
  
  Volume: 114 Issue: 1 Pages: 71-78
- DOI
  10.1093/toxsci/kfp306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241016
[Journal Article] Spontaneous mutagenesis in rodents : spontaneous gene mutations identified by neutral reporter genes in gpt delta transgenic mice and rats2009
- Author(s)
  K. Masumura
- Journal Title
  
  Journal of Health Science 55
  
  Pages: 40-49
- NAID
  110007055908
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201010
[Journal Article] Spontaneous mutagenesis in rodents : spontaneous gene mutations identified by neutral reporter genes in gpt delta transgenic mice and rats2009
- Author(s)
  K. Masumura, T. Nohmi
- Journal Title
  
  J. Health Sci 55
  
  Pages: 40-49
- NAID
  110007055908
- Data Source
  KAKENHI-PROJECT-18201010
[Journal Article] Spontaneous mutagenesis in rodents: spontaneous gene mutations identified by neutral reporter genes in gpt delta transgenic mice and rats2009
- Author(s)
  K. Masumura, T. Nohmi
- Journal Title
  
  J. Health Sci. 55
  
  Pages: 40-49
- NAID
  110007055908
- Data Source
  KAKENHI-PROJECT-18201010
[Journal Article] International symposium on genotoxic and carcinogenic thresholds2008
- Author(s)
  T. Nohmi, N. Toyoda-Hokaiwado, M. Yamada, K. Masumura, M. Honma, S. Fukushima
- Journal Title
  
  Genes and Environ. 30
  
  Pages: 101-107
- NAID
  110007007982
- Data Source
  KAKENHI-PROJECT-18201010
[Journal Article] Enhanced spontaneous and benzo(a)pyrene-induced mutations in the lung of Nrf2-deficient gpt delta mice2007
- Author(s)
  Y. Aoki, A.H. Hashimoto, K. Akanuma, M. Matsumoto, K. Hiyoshi, H. Takano, K. Masumura, K. Itoh, T. Nohmi, M. Yamamoto
- Journal Title
  
  Cancer Res. 67
  
  Pages: 5643-5648
- Data Source
  KAKENHI-PROJECT-18201010
[Patent] 突然変異検出用トランスジェニックラットとその作製方法およびそれを用いた突然変異試験法2006
- Inventor(s)
  能美健彦, 増村健一, 神藤康弘, 林宏行
- Industrial Property Rights Holder
  国立医薬品食品衛生研究所長
- Acquisition Date
  2006-05-12
- Data Source
  KAKENHI-PROJECT-18201010
[Patent] 突然変異検出用トランスジェニックラットとその作製方法およびそれを用いた突然変異試験法2006
- Inventor(s)
  能美健彦、増村健一、神藤康弘、林宏行
- Industrial Property Rights Holder
  国立医薬品食品衛生研究所長
- Filing Date
  2006-05-12
- Acquisition Date
  2006-05-12
- Data Source
  KAKENHI-PROJECT-18201010
[Presentation] In vivo mutagenicity assessment and derivation of reference dose of styrene.2023
- Author(s)
  Murata Y, Matsumoto M, Hirose N, Iso T, Shigeta Y, Hasegawa S, Umano T, Horibata K, Sugiyama K, Inoue K, Hirose A, Masumura K
- Organizer
  57th Congress of the European Societies of Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] 遺伝毒性評価を見据えたECSに関する検討2023
- Author(s)
  松村奨士，大坪裕紀，細井紗弥佳，廣瀬貴子，池田直弘，齋藤和智，伊藤勇一，鈴木孝昌，増村健一，杉山圭一
- Organizer
  第50回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] 肝発がん物質を用いたin vivo変異原性と発がん性の定量的解析2023
- Author(s)
  増村健一，本間正充
- Organizer
  第50回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] トランスジェニックマウスを用いたtert-ブチルヒドロペルオキシドの遺伝子突然変異試験2023
- Author(s)
  村田康允，重田善之，磯貴子，馬野高昭，広瀬望，長谷川彩由香，堀端克良，杉山圭一，広瀬明彦，増村健一，松本真理子
- Organizer
  第50回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] α－（ノニルフェニル）－ω－ヒドロキシポリ（オキシエチレン）の人健康影響に係るスクリーニング評価2023
- Author(s)
  甲斐薫，牛田和夫，山下ルシア幸子，川島明，鈴木洋，井上薫，増村健一
- Organizer
  第50回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] Error-corrected sequencingを用いた遺伝毒性評価法の有用性検証（JEMS/MMS共同研究）2023
- Author(s)
  細井紗弥佳，廣瀬貴子，大坪裕紀，松村奨士，齋藤和智，池田直弘，伊藤勇一，小山直己，川出明弘，羽倉昌志，柿内太，朝倉省二，岡田祐樹，木本崇文，千藏さつき，南結香子，鈴木孝昌，増村健一，杉山圭一
- Organizer
  第50回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] アゾジカルボンアミドのin vivo遺伝毒性評価2023
- Author(s)
  磯貴子，村田康允，広瀬望，馬野高昭，重田善之，長谷川彩由香，堀端克良，六鹿元雄，杉山圭一，広瀬明彦，増村健一，松本真理子
- Organizer
  第50回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] Current status and expectation on error-corrected NGS technology2023
- Author(s)
  Matsumura S, Otsubo Y, Hosoi S, Hirose T, Ikeda N, Yamane M, Suzuki T, Masumura K, Sugiyama K
- Organizer
  45th Environmental Mutagen Society of India (EMSI) Annual Meeting and International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] Error-corrected sequencingを用いた遺伝毒性評価法の有用性検証（JEMS/MMS共同研究）2023
- Author(s)
  大坪裕紀，細井紗弥佳，廣瀬貴子，松村奨士，齋藤和智，池田直弘，宮澤正明，小山直己，川出明弘，羽倉昌志，柿内太，朝倉省二，岡田祐樹，木本崇文，千藏さつき，南結香子，滑川淳一，鈴木孝昌，増村健一，杉山圭一
- Organizer
  日本環境変異原ゲノム学会第52回大会
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] ニトロソアミン変異原性評価の国際動向-CPCAとEAT-2023
- Author(s)
  増村健一
- Organizer
  QSARワークショップ2023（日本環境変異原ゲノム学会第52回大会サテライトミーティング）
- Invited
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] 行政における化学物質リスク評価を支援するAIを用いた安全性予測プラットフォームの開発2023
- Author(s)
  山田隆志，大畑秀雄，古濱彩子，杉山圭一，本間正充，瀬川勝智，斎藤嘉朗，相﨑健一，北嶋聡，広瀬明彦，増村健一
- Organizer
  第50回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] gpt deltaマウスにアクリルアミドが誘発する生殖系列突然変異と曝露時の精子形成ステージの影響2023
- Author(s)
  増村健一，安東朋子，石井雄二，杉山圭一
- Organizer
  日本環境変異原ゲノム学会第52回大会
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] 化審法のリスク評価（一次）評価Ⅰにおける発がん性定量的評価：代表TD50適用に代わる評価値導出方法の検討2023
- Author(s)
  山下ルシア幸子，牛田和夫，甲斐薫，川島明，広瀬明彦，増村健一，井上薫
- Organizer
  第50回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] The gene mutation test of styrene using the transgenic mouse2022
- Author(s)
  村田康允, 磯貴子, 重田義之, 広瀬望, 馬野高昭, 堀端克良, 増村健一, 杉山圭一, 松本真理子, 広瀬明彦
- Organizer
  第49回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-20K12189
[Presentation] Evaluation of the in vivo mutagenicity of Carbendazim2022
- Author(s)
  磯貴子, 村田康允, 重田善之, 広瀬望, 馬野高昭, 堀端克良, 増村健一, 杉山圭一, 松本真理子, 広瀬明彦
- Organizer
  第49回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-20K12189
[Presentation] DNA polymerase kappa不活性化マウスにおいてmitomycin Cによって誘発されるγH2AXの免疫組織学的解析2022
- Author(s)
  竹入章，和田直子，本山茂記，田中美咲，田中健司，松崎香織，松尾沙織里，藤井悦子，三島雅之，寺社下浩一，Petr Gruz，増村健一，能美健彦，杉山圭一，本間正充
- Organizer
  日本環境変異原ゲノム学会第51回大会
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] カルベンダジムのin vivo遺伝毒性評価2022
- Author(s)
  磯貴子，村田康允，重田義之，広瀬望，馬野高昭，堀端克良，増村健一，杉山圭一，松本真理子，広瀬明彦
- Organizer
  第49回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] Error-corrected sequencing (ECS)の有用性検証2022
- Author(s)
  松村奨士，細井紗弥佳，廣瀬貴子，大坪裕紀，池田直弘，山根雅之，鈴木孝昌，増村健一，杉山圭一
- Organizer
  日本環境変異原ゲノム学会第51回大会
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] Mutagenicity in germ cells and de novo mutations in the offspring2022
- Author(s)
  Masumura K
- Organizer
  The 13th International Conference on Environmental Mutagens (ICEM) and the 53rd Annual Meeting of the Environmental Mutagenesis and Genomics Society (EMGS)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] トランスジェニックマウスを用いたスチレンの遺伝子突然変異試験2022
- Author(s)
  村田康允，磯貴子，重田義之，広瀬望，馬野高昭，堀端克良，増村健一，杉山圭一，松本真理子，広瀬明彦
- Organizer
  第49回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] マウス雄性生殖細胞に誘発された点突然変異と次世代個体のde novo 突然変異の解析2022
- Author(s)
  増村健一
- Organizer
  日本放射線影響学会第65回大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] Evaluation of the error-corrected sequencing-based mutagenicity assay using gpt delta mice2022
- Author(s)
  Matsumura S, Hirose T, Otsubo Y, Ikeda N, Yamane M, Suzuki T, Masumura K, Sugiyama K
- Organizer
  The 13th International Conference on Environmental Mutagens (ICEM) and the 53rd Annual Meeting of the Environmental Mutagenesis and Genomics Society (EMGS)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] gpt deltaマウスを用いたアクリルアミドの生殖細胞変異原性と次世代個体ゲノム変異の解析2022
- Author(s)
  増村健一，安東朋子，石井雄二，杉山圭一
- Organizer
  日本環境変異原ゲノム学会第51回大会
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] Mutagenic response of newly developed gpt delta transgenic rat strain with homozygous transgene2021
- Author(s)
  Masumura K, Ando T, Ukai A, Fujiwara S, Yokose S, Takagi H, Nohmi T, Sugiyama K, Honma M.
- Organizer
  52nd annual meeting of Environmental Mutagenesis and Genomics Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] ミスマッチ修復欠損条件下でgpt delta マウス小腸に誘発される特徴的突然変異2021
- Author(s)
  青木康展, 大野みずき, 松本みちよ, 松本理, 増村健一, 能美健彦, 續輝久
- Organizer
  日本環境変異原ゲノム学会第50回記念大会
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] レポーター遺伝子導入マウスとNGSを用いた生殖細胞突然変異の解析2021
- Author(s)
  増村健一
- Organizer
  日本遺伝学会第93回大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] 生殖細胞突然変異と次世代ゲノムへの影響2021
- Author(s)
  増村健一
- Organizer
  日本環境変異原ゲノム学会第50回記念大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] 生殖細胞変異原性と次世代個体ゲノムへの影響2020
- Author(s)
  増村健一
- Organizer
  第47回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] アクリルアミド投与gpt deltaマウスを用いたDNA付加体と点突然変異の用量相関に関する研究2020
- Author(s)
  増村健一，安東朋子，石井雄二，杉山圭一，本間正充
- Organizer
  日本環境変異原学会第49回大会
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] レポーター遺伝子導入マウスとNGSを用いた生殖細胞突然変異の解析2020
- Author(s)
  増村健一
- Organizer
  日本遺伝学会第92回大会
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] Oral administration of hexavalent chromium did not increase mutant frequency in the small Intestine of gpt delta mouse2020
- Author(s)
  Aoki Y, Matsumoto M, Matsumoto M, Masumura K, and Nohmi T
- Organizer
  59th Annual Meeting of the Society of Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] New strain of gpt delta transgenic rat is homozygous for transgene and highly improved packaging efficiency2019
- Author(s)
  Masumura K, Ando T, Ukai A, Fujiwara S, Suzuki T, Yokose S, Takagi H, Nohmi T, Honma M
- Organizer
  The Joint Meeting of the 6th Asian Congress on Environmental Mutagens and the 48th Annual Meeting of the Japanese Environmental Mutagen Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] Dose response of DNA adduct formation and gene mutation induced by acrylamide in gpt delta mice2019
- Author(s)
  Masumura K, Ando T, Ishii Y, Honma M
- Organizer
  50th annual meeting of Environmental Mutagenesis and Genomics Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] Detection of de novo germline mutations in the offspring of mutagen-exposed male mice by whole exome/genome sequencing2019
- Author(s)
  増村健一
- Organizer
  日本放射線影響学会第62回大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] Analyses of ENU-induced germ cell mutations in male mice and inherited germline mutations in the offspring2019
- Author(s)
  Masumura K, Ando T, Toyoda-Hokaiwado N, Ukai A, Nohmi T, Honma M
- Organizer
  The 47th annual meeting of the European Environmental Mutagenesis and Genomics Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12347
[Presentation] ゲノム解析による経世代突然変異の検出2016
- Author(s)
  増村健一
- Organizer
  平成28年度日本環境変異原学会公開シンポジウム
- Place of Presentation
  がん研究振興財団国際交流会館
- Invited
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] マウス肝発がん物質を用いた遺伝毒性および発がん性の定量的分析に関する研究2016
- Author(s)
  増村健一，本間正充
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] Analysis of inherited germline mutations of ENU-treated mice by whole exome sequencing.2016
- Author(s)
  Masumura K, Toyoda-Hokaiwado N, Ukai A, Gondo Y, Honma M, Nohmi T
- Organizer
  Society of Toxicology 55th Annual meeting
- Place of Presentation
  New Orleans (USA)
- Year and Date
  2016-03-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293034
[Presentation] Analysis of inherited germline mutations of ENU-treated mice by whole exome sequencing2016
- Author(s)
  Masumura K, Toyoda-Hokaiwado N, Ukai A, Gondo Y, Honma M, Nohmi T
- Organizer
  Society of Toxicology 55th Annual meeting
- Place of Presentation
  New Orleans Ernest N. Morial Convention Center, LA, USA
- Year and Date
  2016-03-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] Estimation of the frequency of inherited germline mujtations by whole-exome sequencing in ethylnitrosourea-treated gpt delta mice2016
- Author(s)
  Masumura K, Toyoda-Hokaiwado N, Ukai A, Gondo Y, Honma M, Nohmi T
- Organizer
  47th Annual Meeting of Environmental Mutagenesis and Genomics Society
- Place of Presentation
  Westin Kansas City at Crown center
- Year and Date
  2016-09-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] 全エキソーム解析を用いたENU 投与雄マウスの次世代個体における生殖細胞系列突然変異頻度の測定2016
- Author(s)
  増村健一，鵜飼明子，豊田尚美，権藤洋一，能美健彦，本間正充
- Organizer
  日本環境変異原学会第45回大会
- Place of Presentation
  つくば国際会議場
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] DNA polymerase kappaはin vivoにおいて、cisplatinに対する損傷乗越えDNA複製に関与する2015
- Author(s)
  本山茂記、竹入章、松尾沙織里、和田直子、寺社下浩一、三島雅之、新見直子、Petr Gruz、増村健一、山田雅巳、能美健彦
- Organizer
  日本環境変異原学会第44回大会
- Place of Presentation
  九州大学馬出キャンパス
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] トランスジェニック動物遺伝子突然変異試験におけるin vivo変異原性と発がん性の相関に関する研究2015
- Author(s)
  増村健一，森田健，本間正充
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] Detection of rodent carcinogens and non-carcinogens by in vivo erythrocyte micronucleus and transgenic rodent mutation tests2015
- Author(s)
  Morita T, Hamada S, Masumura K, Honnma M
- Organizer
  44th Annual Meeting of European Environmental Mutagenesis and Genomics Society
- Place of Presentation
  Clarion Congress Hotel, Prague, Czech Republic
- Year and Date
  2015-08-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] アクリルアミドの生殖細胞における変異原性の検討2015
- Author(s)
  増村健一
- Organizer
  日本環境変異原学会第44回大会
- Place of Presentation
  九州大学馬出キャンパス（福岡県福岡市）
- Year and Date
  2015-11-28
- Invited
- Data Source
  KAKENHI-PROJECT-25293034
[Presentation] gpt deltaマウスを用いたアクリルアミドの生殖細胞遺伝子突然変異の解析2015
- Author(s)
  萩尾宗一郎，小川いづみ，阿部正義，林清吾，辻菜穂，黒田雄介，古川賢，八木孝司，本間正充，増村健一
- Organizer
  第42回日本毒性学会学術年会
- Place of Presentation
  石川県立音楽堂
- Year and Date
  2015-06-29
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] トランスジェニック動物遺伝子突然変異試験におけるin vivo変異原性と発がん性の相関に関する研究2015
- Author(s)
  増村健一，森田健，本間正充
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-25293034
[Presentation] マウス全エキソーム解析によるENU誘発生殖細胞変異スペクトルの解析2015
- Author(s)
  増村健一、鵜飼明子、豊田尚美、権藤洋一、能美健彦、本間正充
- Organizer
  日本環境変異原学会第44回大会
- Place of Presentation
  九州大学馬出キャンパス
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] gpt deltaマウスの生殖細胞におけるアクリルアミド誘発突然変異の解析2015
- Author(s)
  萩尾宗一郎、阿部正義、林清吾、辻菜穂、黒田雄介、古川賢、八木孝司、本間正充、増村健一
- Organizer
  日本環境変異原学会第44回大会
- Place of Presentation
  九州大学馬出キャンパス（福岡県福岡市）
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-25293034
[Presentation] 都市大気浮粒子抽出物がgpt deltaマウス肺で示す変異原性と突然変異スペクトル2015
- Author(s)
  青木康展、中島大介、松本みちよ、松本理、柳澤利枝、後藤純雄、増村健一、能美健彦
- Organizer
  日本環境変異原学会第44回大会
- Place of Presentation
  九州大学馬出キャンパス
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] アクリルアミドの生殖細胞における変異原性の検討2015
- Author(s)
  増村健一
- Organizer
  日本環境変異原学会第44回大会
- Place of Presentation
  九州大学馬出キャンパス
- Year and Date
  2015-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] Sensitivity of inactivated DNA polymerase kappa knock-in mice to mitomycin C2015
- Author(s)
  Takeiri A, Naoko AW, Motoyama S, Matsuzaki K, Tateishi H, Matsumoto K, Niimi N, Sassa A, Grúz P, Masumura K, Yamada M, Mishima M, Jishage K, Nohmi T
- Organizer
  The 7th International Congress of Asian Society of Toxicology
- Place of Presentation
  International Convention Center Jeju Island, South Korea
- Year and Date
  2015-06-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] gpt deltaマウスの生殖細胞におけるアクリルアミド誘発突然変異の解析2015
- Author(s)
  萩尾宗一郎、阿部正義、林清吾、辻菜穂、黒田雄介、古川賢、八木孝司、本間正充、増村健一
- Organizer
  日本環境変異原学会第44回大会
- Place of Presentation
  九州大学馬出キャンパス
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] In vitroおよびin vivo遺伝毒性試験の組合せによる齧歯類発がん物質の検出力2015
- Author(s)
  森田健、濱田修一、増村健一、本間正充
- Organizer
  日本環境変異原学会第44回大会
- Place of Presentation
  九州大学馬出キャンパス
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] 都市大気浮遊粒子抽出物がgpt deltaマウス肺で示す変異原性と突然変異スペクトル2015
- Author(s)
  青木康展、中島大介、松本みちよ、松本理、柳澤利枝、後藤純雄、増村健一、能美健彦
- Organizer
  日本環境変異原学会第44回大会
- Place of Presentation
  九州大学馬出キャンパス（福岡県福岡市）
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-25293034
[Presentation] マウス全エキソーム解析によるENU誘発生殖細胞変異スペクトルの解析2015
- Author(s)
  増村健一、鵜飼明子、豊田尚美、権藤洋一、能美健彦、本間正充
- Organizer
  日本環境変異原学会第44回大会
- Place of Presentation
  九州大学馬出キャンパス（福岡県福岡市）
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-25293034
[Presentation] ICHガイドラインS2（R1）におけるin vivo試験組合せの検討2015
- Author(s)
  山田雅巳、大杉直弘、髙木久宜、和田邦生、松元郷六、大隅友香、真田尚和、百南綾華、堤絵梨、堀妃佐子、赤沼三恵、増村健一、本間正充
- Organizer
  日本環境変異原学会第44回大会
- Place of Presentation
  九州大学馬出キャンパス
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] gpt deltaマウスを用いた加齢に伴い蓄積する遺伝子突然変異の解析2014
- Author(s)
  増村健一，大杉直弘，豊田尚美，能美健彦，本間正充
- Organizer
  日本進化学会第16回大会
- Place of Presentation
  高槻現代劇場（大阪府高槻市）
- Year and Date
  2014-08-23
- Data Source
  KAKENHI-PROJECT-25293034
[Presentation] Point mutations and deletions induced by aging in liver of gpt delta transgenic rats2014
- Author(s)
  Masumura K, Toyoda-Hokaiwado N, Ishii Y, Umemura T, Honma M, Nishikawa A, Nohmi T,
- Organizer
  4th Asian Conference on Environmental Mutagens
- Place of Presentation
  インド化学生物研究所（コルカタ、インド）
- Year and Date
  2014-12-10
- Data Source
  KAKENHI-PROJECT-25293034
[Presentation] DMHを用いたF344系統gpt deltaラット突然変異試験と小核試験(末梢血，骨髄，肝臓，大腸)の統合法の検討2014
- Author(s)
  堀妃佐子，田中康浩，堤絵梨，百南綾香，増村健一，山田雅巳，藤居亙，北川義徳
- Organizer
  日本環境変異原学会第43回大会
- Place of Presentation
  学術総合センター（東京都千代田区）
- Year and Date
  2014-12-05
- Data Source
  KAKENHI-PROJECT-25293034
[Presentation] ベンゾ[a]ピレンを気管内投与したgpt deltaマウス肺中に誘導された突然変異の加齢に伴う変化2014
- Author(s)
  青木康展，橋本顕子，菅原良樹，荒井孝子，後藤佐多良、増村健一，能美健彦
- Organizer
  日本環境変異原学会第43回大会
- Place of Presentation
  学術総合センター（東京都千代田区）
- Year and Date
  2014-12-05
- Data Source
  KAKENHI-PROJECT-25293034
[Presentation] トランスジェニック動物を用いた遺伝子突然変異試験の動向2014
- Author(s)
  増村健一
- Organizer
  MMS研究会第64回定例会
- Place of Presentation
  森の温泉ホテル（静岡県熱海市）
- Year and Date
  2014-06-21
- Data Source
  KAKENHI-PROJECT-25293034
[Presentation] gpt deltaラットの加齢により誘発される点突然変異および欠失変異の解析2014
- Author(s)
  増村健一，豊田尚美，石井雄二，梅村隆志，能美健彦，西川秋佳，本間正充
- Organizer
  第37回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-25293034
[Presentation] Mitomycin CによるDNA損傷に対するDNA polymerase kappaの役割 -γH2AXを指標にした免疫組織学的解析-2014
- Author(s)
  本山茂記，竹入章，松尾沙織里，和田直子，寺社下浩一，三島雅之，新見直子，Petr Gruz，増村健一，山田雅巳，能美健彦
- Organizer
  日本環境変異原学会第43回大会
- Place of Presentation
  学術総合センター（東京都千代田区）
- Year and Date
  2014-12-04
- Data Source
  KAKENHI-PROJECT-25293034
[Presentation] F344系gpt deltaラットを用いた突然変異試験と小核試験（末梢血，骨髄，肝臓，大腸）の統合法の検討2013
- Author(s)
  堀妃佐子，田中康浩，増村健一，山田雅巳，藤居亙
- Organizer
  日本環境変異原学会第42回大会
- Place of Presentation
  岡山コンベンションセンター（岡山県岡山市）
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] gpt deltaマウスを用いたENU誘発突然変異と全エクソンシークエンスによる経世代変異の検出2013
- Author(s)
  増村健一，豊田尚美，権藤洋一，能美健彦，本間正充
- Organizer
  日本環境変異原学会第42回大会
- Place of Presentation
  岡山コンベンションセンター（岡山県岡山市）
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] 臭素酸カリウムがgpt deltaマウス小腸で誘導する突然変異の閾値と変異スペクトルの用量依存性変化2013
- Author(s)
  青木康展，松本みちよ，松本理，増村健一，續輝久，能美健彦
- Organizer
  日本環境変異原学会第42回大会
- Place of Presentation
  岡山コンベンションセンター（岡山県岡山市）
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] gpt deltaラット肝臓における自然突然変異および加齢に伴う変異蓄積の検討2013
- Author(s)
  増村健一，豊田尚美，石井雄二，梅村隆志，能美健彦，西川秋佳，本間正充
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] gpt deltaマウスを用いたENU誘発突然変異と全エクソンシークエンスによる経世代変異の検出2013
- Author(s)
  増村健一，豊田尚美，権藤洋一，能美健彦，本間正充
- Organizer
  日本環境変異原学会第42回大会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-22241016
[Presentation] Spontaneous point mutations and deletions increased with aging in gpt delta transgenic mice and rats2013
- Author(s)
  K. Masumura, N. Toyoda-Hokaiwado, N. Osugi, Y. Ishii, T. Umemura, H. Takagi, A. Nishikawa, T. Nohmi and M. Honma
- Organizer
  11th International Conference on Environmental Mutagens
- Place of Presentation
  Iguacu, Brazil
- Data Source
  KAKENHI-PROJECT-22241016
[Presentation] Analysis of mutation in the liver of gpt delta rats given a choline-deficient, L-amino acid-defined diet: interplay among nutrition, mutation and cancer2013
- Author(s)
  T. Nohmi, K. Masumura and D. Nakae
- Organizer
  4th International Conference on Nutrition and Physical Activities on Aging, Obesity and Cancer
- Place of Presentation
  Pattaya, Thailand
- Invited
- Data Source
  KAKENHI-PROJECT-22241016
[Presentation] Mitomycin C によるDNA二本鎖切断誘発に対するDNA polymerase kappaのin vivoにおける役割2013
- Author(s)
  本山茂樹，竹入章，松尾沙織里，和田直子，寺社下浩一，三島雅之，新見直子，Petr Gruz，増村健一，山田雅巳，能美健彦
- Organizer
  日本環境変異原学会第42回大会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-22241016
[Presentation] 臭素酸カリウムがgpt deltaマウス小腸で誘発する突然変異の閾値と変異スペクトルの用量依存性変化2013
- Author(s)
  青木康展，松本みちよ，松本理，増村健一，續輝久，能美健彦
- Organizer
  日本環境変異原学会第42回大会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-22241016
[Presentation] Spontaneous point mutations and deletions increased with aging in gpt delta transgenic mice and rats2013
- Author(s)
  Masumura K, Toyoda-Hokaiwado N, Osugi N, Ishii Y, Umemura T, Takagi H, Nishikawa A, Nohmi T, Honma M
- Organizer
  11th International Conference on Environmental Mutagens
- Place of Presentation
  Bourbon Cataratas Convention & Spa Resort, Foz do Iguazu, Brazil
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] MitomycinCによるDNA二本鎖切断誘発に対するDNA polymerase kappaのin vivoにおける役割2013
- Author(s)
  本山茂記，竹入章，松尾沙織里，和田直子，寺社下浩一，三島雅之，新見直子，Gruz P，増村健一，山田雅巳，能美健彦
- Organizer
  日本環境変異原学会第42回大会
- Place of Presentation
  岡山コンベンションセンター（岡山県岡山市）
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] Spontaneous point mutations and deletions induced in liver and testis of aged gpt delta transgenic mice2012
- Author(s)
  K. Masumura
- Organizer
  The 3rd Conference on Environmental Mutgens and 15th Conference on Chinese Environmental Mutagen Society
- Place of Presentation
  Hangzhou, China
- Data Source
  KAKENHI-PROJECT-22241016
[Presentation] gpt deltaマウスおよびラットを用いた自然突然変異および誘発突然変異の解析2012
- Author(s)
  増村健一
- Organizer
  日本環境変異原学会第41回大会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-22241016
[Presentation] Characteristics of point mutations and deletions accumulated with aging of gpt delta transgenic mice2012
- Author(s)
  K. Masumura
- Organizer
  European Environmental Mutagen Society
- Place of Presentation
  Warsaw, Poland
- Data Source
  KAKENHI-PROJECT-22241016
[Presentation] Spontaneous point mutations and deletions accumulate in a different manner with aging of gpt delta transgenic mice2012
- Author(s)
  K. Masumura
- Organizer
  51st Annual Meeting of Society of Toxicology
- Place of Presentation
  San Francisco, U.S.A.
- Data Source
  KAKENHI-PROJECT-22241016
[Presentation] gpt deltaマウスの加齢に伴う点突然変異および欠失変異の蓄積2011
- Author(s)
  増村健一
- Organizer
  日本環境変異原学会第40回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22241016
[Presentation] Genotoxic thresholds : identification of mutations in vivo and mechanistic studies in vitro2011
- Author(s)
  T. Nohmi, K. Masumura, P Gruz, N. Toyoda-Hokaiwado, M. Takamune, N. Niimi, T. Suzuki, Y. Kanemaru, M. Yasui, M. Yamada, M. Honma, N. Adachi and A. Nishikawa
- Organizer
  2nd International Symposium on Genotoxic and Carcinogenic Thresholds
- Place of Presentation
  Tokyo
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-22241016
[Presentation] Chemopreventive effects of silymarin on mutagenesis and carcinogenesis in gpt delta transgenic rats2010
- Author(s)
 K.Masumura
- Organizer
 The 2^<nd> Asian Conference on Environmental Mutagens
- Place of Presentation
 タイ、パタヤ
- Year and Date
 2010-12-17
- Data Source
 KAKENHI-PROJECT-22241016
[Presentation] DNAポリメラーゼκノックインマウスにおける自然突然変異の解析2010
- Author(s)
  増村健一
- Organizer
  日本環境変異原学会第39回大会
- Place of Presentation
  つくば
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-22241016
[Presentation] in vivo mutagenicity of structural isomers 2, 4-DAT and 2, 6-DAT in the target organ for carcinogenicity in F344 gpt delta transgenic rat2009
- Author(s)
 増村健一
- Organizer
 10^<th> International Conference on Environmental Mutagens
- Place of Presentation
 フィレンツェ、イタリア
- Year and Date
 2009-08-22
- Data Source
 KAKENHI-PROJECT-18201010
[Presentation] 次世代DNAシークエンサーを用いた gpt delta トランスジェニックマウスのトランスジーン挿入部位の解析2009
- Author(s)
  増村健一
- Organizer
  日本環境変異原学会第38回大会
- Place of Presentation
  静岡
- Year and Date
  2009-11-26
- Data Source
  KAKENHI-PROJECT-18201010
[Presentation] p53はUVB照射および非照射マウスの表皮で誘発される欠失変異を抑制する2008
- Author(s)
  増村健一
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋、愛知
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-18201010
[Presentation] gpt delta トランスジェニックマウスおよびラットにおける自然突然変異の解析2008
- Author(s)
  増村健一
- Organizer
  日本環境変異原学会第37回大会
- Place of Presentation
  宜野湾、沖縄
- Year and Date
  2008-12-04
- Data Source
  KAKENHI-PROJECT-18201010
[Presentation] Suppression of radiation-induced large deletions by combined treatments with a tobacco-specific nitrosamine in the lung of gpt delta transgenic mice,New Nuclear Research Symposium2007
- Author(s)
  M.Ikeda, K.Masumura, Y.Sakamoto, B.Wang, M.Nenoi, K.Sakuma, I.Hayata, and T.Nohmi
- Organizer
  New Nuclear Research Symposium, Biological Responses to Low Dose Radiation
- Place of Presentation
  千葉
- Year and Date
  2007-11-14
- Data Source
  KAKENHI-PROJECT-18201010
[Presentation] Chemopreventive effects of nobiletin,a citrus constituent,against the genotoxicity of NNK,a tobacco-specific nitrosamine,in the lung of gpt delta transgenic mice2007
- Author(s)
 M.Ikeda, K.Masumura, K.Matsui, H.Kohno, K.Sakuma, T.Tanaka, T.Kamataki, and T.Nohmi
- Organizer
 The 9^<th>International Conference on Mechanisms of Antimutagenesis and Anticarcinogenesis(ICMAA-2007)
- Place of Presentation
 Cheju,Korea
- Year and Date
 2007-12-04
- Data Source
 KAKENHI-PROJECT-18201010
[Presentation] Chemopreventive effects of nobiletin against genotoxicity induced by NNK in the lung of gpt delta transgenic mice2007
- Author(s)
 K.Masumura, M.Ikeda, K.Matsui, T.Tanaka, and T.Nohmi
- Organizer
 1^<st>Asian Conference on Environmental Mutagens(1^<st>ACEM)/36^<th>Annual Meeting of the Japanese Environmental Mutagen Society(36^<th>JEMS)
- Place of Presentation
 北九州
- Year and Date
 2007-11-29
- Data Source
 KAKENHI-PROJECT-18201010
[Presentation] Antigenotoxic effects of p53 on UVB-induced and spontaneous dele tions in the murine epidermis2007
- Author(s)
 Y.Sakamoto, M.Ikeda, K.Masumura, Y.Asami, T.Tsukamoto, H.Ikehata, Y.Kuroiwa, T.Umemura, A.Nishikawa, M.Tatematsu, T.Ono and T.Nohmi
- Organizer
 1^<st>Asian Conference on Environmental Mutagens(1^<st>ACEM)/36^<th>Annual Meeting of the Japanese Environmental Mutagen Society(36^<th>JEMS)
- Place of Presentation
 北九州
- Year and Date
 2007-11-29
- Data Source
 KAKENHI-PROJECT-18201010
[Presentation] アスコルビン酸と亜硝酸ナトリウム複合影響による変異原性ならびにラット前胃発がんイニシェーション作用の検索2007
- Author(s)
  黒岩有一、山田雅巳、松井恵子、増村健一、岡村俊也、田崎雅子、梅村隆志、能美健彦、西川秋佳、広瀬雅雄
- Organizer
  第34回日本トキシコロジー学会学術年会
- Place of Presentation
  東京
- Year and Date
  2007-06-27
- Data Source
  KAKENHI-PROJECT-18201010
[Presentation] in vivo mutations by 3,6-dinitrobenzo[e]pyrene instilled into the lung of gpt delta transgenic mice2007
- Author(s)
 M.Matsumoto, K.Amanuma, A. H.Hashimoto, Y.Sakashita, R.Yanagisawa, H.Takano, K.Masumura, T.Nohmi, K.Wakabyashi, T.Watanabe, and Y.Aoki
- Organizer
 1^<st>Asian Conference on Environmental Mutagens(1^<st>ACEM)/36^<th>Annual Meeting of the Japanese Environmental Mutagen Society(36^<th>JEMS)
- Place of Presentation
 北九州
- Year and Date
 2007-11-29
- Data Source
 KAKENHI-PROJECT-18201010
[Presentation] gpt-deltaマウスを用いた複合曝露胸腺細胞における欠失変異の解析2007
- Author(s)
  山内一己, 柿沼志津子, 須藤聡美, 太田有紀, 鬼頭誠司, 増村健一, 能美健彦, 西村まゆみ, 島田義也
- Organizer
  日本放射線影響学会第50回大会
- Place of Presentation
  千葉
- Year and Date
  2007-11-14
- Data Source
  KAKENHI-PROJECT-18201010
[Presentation] Existence of thresholds for carcinogenicity and in vivo mutagenicity of 1,4-dioxane in liver of rats2007
- Author(s)
  大西真理子, 大森雅子, 魏民, 増村健一, 能美健彦, 鰐淵英機, 福島昭治
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-18201010
[Presentation] DMHを用いたF344系統gpt deltaラット突然変異試験と小核試験(末梢血，骨髄，肝臓，大腸)の統合法の検討
- Author(s)
  堀妃佐子，田中康浩，堤絵梨，百南綾香，増村健一，山田雅巳，藤居亙，北川義徳
- Organizer
  日本環境変異原学会第43回大会
- Place of Presentation
  一橋講堂
- Year and Date
  2014-12-04 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] gpt deltaラットの加齢により誘発される点突然変異および欠失変異の解析
- Author(s)
  増村健一，豊田尚美，石井雄二，梅村隆志，能美健彦，西川秋佳，本間正充
- Organizer
  第37回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] Mitomycin CによるDNA損傷に対するDNA polymerase kappaの役割 -γH2AXを指標にした免疫組織学的解析
- Author(s)
  本山茂記，竹入章，松尾沙織里，和田直子，寺社下浩一，三島雅之，新見直子，Petr Grúz，増村健一，山田雅巳，能美健彦
- Organizer
  日本環境変異原学会第43回大会
- Place of Presentation
  一橋講堂
- Year and Date
  2014-12-04 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] 第6回IWGT報告およひ共同研究進捗報告：生殖細胞に影響を及ぼす変異原の同定
- Author(s)
  増村健一
- Organizer
  日本環境変異原学会MMS研究会第63回定例会
- Place of Presentation
  就実大学（岡山県岡山市）
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] マウス全エクソンシークエンス解析による経世代突然変異の測定
- Author(s)
  増村健一，豊田尚美，権藤洋一，能美健彦，本間正充
- Organizer
  日本環境変異原学会第43回大会
- Place of Presentation
  一橋講堂
- Year and Date
  2014-12-04 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] gpt deltaマウスを用いたアクリルアミドの生殖細胞に対する遺伝毒性評価
- Author(s)
  萩尾宗一郎，小川いづみ，阿部正義，林清吾，辻菜穂，黒田雄介，古川賢，八木孝司，本間正充，増村健一
- Organizer
  日本環境変異原学会第43回大会
- Place of Presentation
  一橋講堂
- Year and Date
  2014-12-04 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] gpt deltaマウスを用いた加齢に伴い蓄積する遺伝子突然変異の解析
- Author(s)
  増村健一，大杉直弘，豊田尚美，能美健彦，本間正充
- Organizer
  日本進化学会第16回大会
- Place of Presentation
  高槻現代劇場
- Year and Date
  2014-08-21 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] トランスジェニック動物を用いた遺伝子突然変異試験の動向
- Author(s)
  増村健一
- Organizer
  MMS研究会第64回定例会
- Place of Presentation
  熱海森の温泉ホテル
- Year and Date
  2014-06-20 – 2014-06-21
- Invited
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] Aging and accumulation of gene mutations: Identification of spontaneous mutations in the tissues of gpt delta transgenic mice
- Author(s)
  Masumura K
- Organizer
  National Cancer Forum 2013
- Place of Presentation
  Centara Grand at Central Plaza Ladprao, Bangkok, Thailand
- Invited
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] Point mutations and deletions induced by aging in liver of gpt delta transgenic rats
- Author(s)
  Masumura K, Toyoda-Hokaiwado N, Ishii Y, Umemura T, Honma M, Nishikawa A, Nohmi T
- Organizer
  4th Asian Conference on Environmental Mutagens
- Place of Presentation
  CSIR-Indian Institute of Chemical Biology, Kolkata, India
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25281027
[Presentation] ベンゾ[a]ピレンを気管内投与したgpt deltaマウス肺中に誘導された突然変異の加齢に伴う変化
- Author(s)
  青木康展，橋本顕子，菅原良樹，荒井孝子，後藤佐多良、増村健一，能美健彦
- Organizer
  日本環境変異原学会第43回大会
- Place of Presentation
  一橋講堂
- Year and Date
  2014-12-04 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-25281027
[]

1. NOUMI Takehiko (30150890)

# of Collaborated Projects: 3 results

# of Collaborated Products: 46 results
2. Horibata Katsuyoshi (40402995)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
3. TOYODA Naomi (70381853)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
4. YASUI Manabu (50435707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. SAJI Tetsuya (20573950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. GRUZ Petr (10321853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. HONMA Masamitsu (30250179)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
8. Aoki Yasunobu (20159297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. NAKAJIMA Daisuke (10281411)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. NOHARA Keiko (50160271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MATSUMOTO Michi (60132867)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. YANAGISAWA Rie (70391167)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. GOTO Sumio (30112890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. NAKAE Dai (90207712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TAKAHASHI Masakazu (50132767)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 山田雅巳 (80230481)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. OHNO Mizuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 権藤洋一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
19. 續輝久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Masumura Kenichi 増村 健一

MASUMURA Kenichi 増村 健一

Research Projects

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遺伝情報発現と遺伝子突然変異の相関

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A study on DNA damages in germ cells of male mice and germline mutations induced in the offspringPrincipal Investigator

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Analysis of mutagenesis relating to DNA topology, transcription and DNA repair

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Studies on quantitative evaluation of inherited germline mutationsPrincipal Investigator

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Assessment of current lung cancer and related health risk by past-exposure of particulates suspended in air

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Studies on mechanisms underlying genotoxic thresholds through genetic modification of DNA polymerase zeta

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Studies on roles of translesion DNA synthesis in thresholds for genotoxic substances

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1分子PCR法を用いた次世代遺伝毒性試験法の開発Principal Investigator

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Study on the Mechanisms Underlying Endogenous Hepatocarcinogenesis Induced Only by the Manipulation of Food Composition

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[Book] 衛生試験法・注解2020，1.3 遺伝毒性試験法 p135-1672020

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[Book] 第9版食品添加物公定書解説書2019

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[Book] 衛生試験法・注解20152015

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[Book] 衛生試験法・注解2015，1.3 遺伝毒性試験法，1.3.3げっ歯類を用いる試験，(2)トランスジェニック動物遺伝子突然変異試験2015

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Masumura Kenichi 増村健一

MASUMURA Kenichi 増村健一

[Journal Article] Absence of <i>in vivo</i> mutagenicity of 4,4'-oxybis(benzenesulfonohydrazide) in liver and glandular stomach of Muta<sup>TM</sup> Mouse2022