Kono Hidetoshi 河野秀俊

… Alternative Names

KONO Hidetoshi 河野秀俊

河野秀俊コウノヒデトシ

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Researcher Number	40291918
Other IDs
External Links
Affiliation (Current)	2025: 国立研究開発法人量子科学技術研究開発機構, 量子生命科学研究所, 副所長
Affiliation (based on the past Project Information) *help	2022: 国立研究開発法人量子科学技術研究開発機構, 量子生命科学研究所, プロジェクトディレクター 2021: 国立研究開発法人量子科学技術研究開発機構, 量子生命科学研究所, グループリーダー 2020: 国立研究開発法人量子科学技術研究開発機構, 量子生命科学領域, グループリーダー(定常) 2016 – 2019: 国立研究開発法人量子科学技術研究開発機構, 関西光科学研究所量子生命科学研究部, グループリーダー(定常) 2017: 量子科学技術研究開発機構, グループリーダー … More 2016: 量子科学技術研究開発機構, 量子生命科学研究部, 生体分子シミュレーショングループリーダー 2015: 国立研究開発法人日本原子力研究開発機構, 原子力科学研究部門量子ビーム応用研究センター, 研究主幹 2013 – 2014: 独立行政法人日本原子力研究開発機構, 原子力科学研究部門量子ビーム応用研究センター, 研究主幹 2009 – 2012: Japan Atomic Energy Agency, 量子ビーム応用研究部門, 研究主幹 2007 – 2008: Japan Atomic Energy Agency, 量子ビーム応用研究部門, 研究主幹 2006: 独立行政法人日本原子力研究開発機構, 量子ビーム応用研究部門, 研究副主幹 2004: 特殊法人日本原子力研究所, 中性子利用研究センター兼計算科学技術推進センター, 副主任研究員 2004: 特殊法人日本原子力研究所, 計算科学技術推進センター, 副主任研究員 2003: 特殊法人日本原子力研究所, 計算科学技術推進センター, 研究員 1998: 理化学研究所, ジーンバンク室, 基礎科学特別研究員 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Biological Sciences / Life / Health / Medical informatics / ゲノム情報科学 / Bioinformatics/Life informatics / Science and Engineering / 基礎ゲノム科学 Except Principal Investigator Biological Sciences
Keywords	Principal Investigator ヌクレオソーム / クロマチン / 分子動力学計算 / ゲノム / 生体生命情報学 / 分子シミュレーション / 分子設計 / DNA結合蛋白質 / 自由エネルギー / 生体生命情報 … More / ヒストン修飾 / バイオインフォマティクス / 蛋白質設計 / 転写因子 / デザイン / DNA結合タンパク質 / モデリング / 配列特異性 / DNA結合 / タンパク質設計 / B1H / アンサンブル / エピゲノム / 翻訳後修飾 / シミュレーション / ヒストン / 特異的認識 / エピジェネティクス / タンパク質-核酸 / 制御 / 遺伝子発現 / 転写 / 構造変形 / タンパク質-DNA相互作用 / 構造変化 / DNA / 水和 / 発現制御 / 蛋白質 / 核酸 / 機能部位予測 / 平均場近似 / プロファイル / 統計ポテンシャル / 蛋白質-DNA複合体 … More Except Principal Investigator 遺伝情報複製・再編 / エピジェネティクス / クロマチン / 活性発現の分子機構 / 生体高分子構造・機能 / 構造活性相関 / ゲノム進化・再編 / ゲノム維持修復 / 生体高分子構造・機能ゲノム進化・再編 / ゲノム多様性 / 染色体構築・機能・分配 / ゲノム機能 / ヌクレオソーム / 遺伝子 / 転写 / 遺伝子発現 / クライオ電子顕微鏡 / クロマチン再構成 / クロマチン転写 / ヒストン / 染色体 / ゲノム / ポリメラーゼ / 蛋白質 / 生体分子 / 生物物理 / 生体生命情報学 / 分子動力学計算 / 転写因子 / DNA結合蛋白質 / cavity / 構造安定性 Less

Elucidation of chromatin potential through the analysis of nucleosome structure and dynamics
- Principal Investigator
  
  Kurumizaka Hitoshi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
International research network for chromatin structure, dynamics, and function
- Principal Investigator
  
  Kurumizaka Hitoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Waseda University
Improvement of sequence specificity of DNA-binding protein using computational and experimental approachesPrincipal Investigator
- Principal Investigator
  
  KONO HIDETOSHI
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Life / Health / Medical informatics
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
  Japan Atomic Energy Agency
Chromatin dynamics analysis using computer simulationPrincipal Investigator
- Principal Investigator
  
  Kono Hidetoshi
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
  Japan Atomic Energy Agency
Chromatin structure, dynamics, and function
- Principal Investigator
  
  Kurumizaka Hitoshi
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Waseda University
Elucidation of information-processing mechanisms during transcription cycle using computational and information sciences
- Principal Investigator
  
  NAKAMURA Haruki
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
ヌクレオソーム構造の自由エネルギープロファイル解析Principal Investigator
- Principal Investigator
  
  河野秀俊
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Japan Atomic Energy Agency
シミュレーション計算によるヌクレオソーム構造形成の自由エネルギー地形解析Principal Investigator
- Principal Investigator
  
  河野秀俊
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Japan Atomic Energy Agency
DNA配列に特異的に結合するタンパク質分子設計Principal Investigator
- Principal Investigator
  
  河野秀俊
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  ゲノム情報科学
- Research Institution
  Japan Atomic Energy Agency
Regulation of Gene Transcription Inferred From Transcription Factor Binding and Nucleosome PositioningPrincipal Investigator
- Principal Investigator
  
  KONO Hidetoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioinformatics/Life informatics
- Research Institution
  Japan Atomic Energy Agency
中性子散乱実験と分子動力学計算による蛋白質-DNA認識機構における水の挙動解析Principal Investigator
- Principal Investigator
  
  河野秀俊
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Japan Atomic Energy Agency
転写因子のターゲット部位予側にもとづく遺伝子の機能及び相互作用推定Principal Investigator
- Principal Investigator
  
  河野秀俊
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japan Atomic Energy Agency
転写因子のターゲット部位予側からのゲノム機能推定Principal Investigator
- Principal Investigator
  
  河野秀俊
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japan Atomic Energy Agency
蛋白質の機能部位推定及びSNPによる機能変化の予側Principal Investigator
- Principal Investigator
  
  河野秀俊
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  基礎ゲノム科学
- Research Institution
  Japan Atomic Energy Agency
DNA結合蛋白質の機能性cavityと立体構造安定性
- Principal Investigator
  
  皿井明倫
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The Institute of Physical and Chemical Research

[Book] DNAの水和水とダイナミクスの塩基配列依存症-DNA-タンパク質、DNA-低分子認識の理解に向けて(揺らぎと生体機能10月別冊)2010
- Author(s)
  米谷佳晃,河野秀俊
- Publisher
  メディカルバイオ
- Data Source
  KAKENHI-PROJECT-20300103
[Book] Chapter 13 Rotamer Libraries for Molecular Modeling and Design of Proteins (Protein Design and Engineering)2009
- Author(s)
  Hidetoshi Kono
- Total Pages
  12
- Publisher
  Taylor & Francis Group
- Data Source
  KAKENHI-PROJECT-20300103
[Book] Chapter 13 Rotamer Libraries for Molecular Modeling and Design of Proteins (Protein Design and Engineering)2009
- Author(s)
  河野秀俊
- Publisher
  Park&Cochran, Taylor & Francis Group
- Data Source
  KAKENHI-PROJECT-20300103
[Book] タンパク質とDNAの結合予測.実験医学増刊号(26)2008
- Author(s)
  皿井明倫,河野秀俊
- Publisher
  バイオデータベースとソフトウェア最前線
- Data Source
  KAKENHI-PROJECT-20300103
[Journal Article] HNF1A POU Domain Mutations Found in Japanese Liver Cancer Patients Cause Downregulation of HNF4A Promoter Activity with Possible Disruption in Transcription Networks2022
- Author(s)
  Haque Effi、Teeli Aamir Salam、Winiarczyk Dawid、Taguchi Masahiko、Sakuraba Shun、Kono Hidetoshi、Leszczynski Pawel、Pierzchala Mariusz、Taniguchi Hiroaki
- Journal Title
  
  Genes
  
  Volume: 13 Issue: 3 Pages: 413-413
- DOI
  10.3390/genes13030413
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534
[Journal Article] Overall structure of fully assembled cyanobacterial KaiABC circadian clock complex by an integrated experimental-computational approach2022
- Author(s)
  Yunoki Yasuhiro、Matsumoto Atsushi、Morishima Ken、Martel Anne、Porcar Lionel、Sato Nobuhiro、Yogo Rina、Tominaga Taiki、Inoue Rintaro、Yagi-Utsumi Maho、Okuda Aya、Shimizu Masahiro、Urade Reiko、Terauchi Kazuki、Kono Hidetoshi、Yagi Hirokazu、Kato Koichi、Sugiyama Masaaki
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 184-184
- DOI
  10.1038/s42003-022-03143-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534, KAKENHI-PROJECT-19K05833, KAKENHI-PROJECT-20K06579, KAKENHI-PROJECT-19KK0071, KAKENHI-PROJECT-21K15051, KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-20K22629
[Journal Article] 時計タンパク質複合体の構造解析を通して明らかとなった中性子小角散乱の強み2022
- Author(s)
  柚木康弘、松本淳、守島健、Martel Anne、Porcar Lionel、佐藤信浩、與語理那、富永大輝、矢木真穂、井上倫太郎、河野秀俊、矢木宏和、加藤晃一、杉山正明
- Journal Title
  
  波紋
  
  Volume: 32 Pages: 158-164
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534
[Journal Article] Free Energy Landscape of H2A-H2B Displacement From Nucleosome2022
- Author(s)
  Ishida Hisashi、Kono Hidetoshi
- Journal Title
  
  Journal of Molecular Biology
  
  Volume: 434 Issue: 16 Pages: 167707-167707
- DOI
  10.1016/j.jmb.2022.167707
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05534
[Journal Article] RNAPII driven post-translational modifications of nucleosomal histones2022
- Author(s)
  Chan Justin、Kumar Amarjeet、Kono Hidetoshi
- Journal Title
  
  Trends in Genetics
  
  Volume: 38 Issue: 10 Pages: 1076-1095
- DOI
  10.1016/j.tig.2022.04.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05534
[Journal Article] Fly casting with ligand sliding and orientational selection supporting complex formation of a GPCR and a middle sized flexible molecule.2022
- Author(s)
  Junichi Higo, Kota Kasahara, Gert-Jan Bekker, Benson Ma, Shun Sakuraba, Shinji Iida, Narutoshi Kamiya, Ikuo Fukuda, Hidetoshi Kono, Yoshifumi Fukunishi, Haruki Nakamura
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 13792-13792
- DOI
  10.1038/s41598-022-17920-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06052, KAKENHI-PLANNED-18H05534
[Journal Article] Chemical catalyst/protein hybrid as artificial histone-modifying enzyme for epigenome manipulation2022
- Author(s)
  Fujimura Akiko、Ishida Hisashi、Nozaki Tamiko、Azumaya Yuto、Ishiguro Tadashi、Kujirai Tomoya、Kurumizaka Hitoshi、Kono Hidetoshi、Yamatsugu Kenzo、Kawashima Shigehiro、Kanai Motomu
- Journal Title
  
  ChemRxiv
  
  Volume: -
- DOI
  10.26434/chemrxiv-2022-xt610
- Open Access
- Data Source
  KAKENHI-PLANNED-18H05534
[Journal Article] Interplay among transacting factors around promoter in the initial phases of transcription2021
- Author(s)
  Kumar Amarjeet、Chan Justin、Taguchi Masahiko、Kono Hidetoshi
- Journal Title
  
  Current Opinion in Structural Biology
  
  Volume: 71 Pages: 7-15
- DOI
  10.1016/j.sbi.2021.04.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534
[Journal Article] NRF2 DLG Domain Mutations Identified in Japanese Liver Cancer Patients Affect the Transcriptional Activity in HCC Cell Lines2021
- Author(s)
  Haque Effi、Smiech Magdalena、Luczynska Kamila、Bouchard Marie France、Viger Robert、Kono Hidetoshi、Pierzchala Mariusz、Taniguchi Hiroaki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 10 Pages: 5296-5296
- DOI
  10.3390/ijms22105296
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534
[Journal Article] Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD22021
- Author(s)
  Sato Ko、Kumar Amarjeet、Hamada Keisuke、Okada Chikako、Oguni Asako、Machiyama Ayumi、Sakuraba Shun、Nishizawa Tomohiro、Nureki Osamu、Kono Hidetoshi、Ogata Kazuhiro、Sengoku Toru
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 6605-6605
- DOI
  10.1038/s41467-021-26913-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534, KAKENHI-PUBLICLY-20H05394, KAKENHI-ORGANIZER-21H05158, KAKENHI-PROJECT-20K08717
[Journal Article] The N-terminal Tails of Histones H2A and H2B Adopt Two Distinct Conformations in the Nucleosome with Contact and Reduced Contact to DNA2021
- Author(s)
  Ohtomo Hideaki、Kurita Jun-ichi、Sakuraba Shun、Li Zhenhai、Arimura Yasuhiro、Wakamori Masatoshi、Tsunaka Yasuo、Umehara Takashi、Kurumizaka Hitoshi、Kono Hidetoshi、Nishimura Yoshifumi
- Journal Title
  
  Journal of Molecular Biology
  
  Volume: 433 Issue: 15 Pages: 167110-167110
- DOI
  10.1016/j.jmb.2021.167110
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534
[Journal Article] Torsional stress can regulate the unwrapping of two outer half superhelical turns of nucleosomal DNA2021
- Author(s)
  Ishida Hisashi、Kono Hidetoshi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 118 Issue: 7
- DOI
  10.1073/pnas.2020452118
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05534, KAKENHI-PROJECT-18K06173
[Journal Article] Sequence-dependent Hydration Water Dynamics of Dodecameric DNA2021
- Author(s)
  Nakagawa Hiroshi、Yonetani Yoshiteru、Nakajima Kenji、Ohira-Kawamura Seiko、Kikuchi Tatsuya、Inamura Yasuhiro、Kataoka Mikio、Kono Hidetoshi
- Journal Title
  
  Proceedings of the J-PARC Symposium 2019, JPS
  
  Volume: 33 Pages: 011101-011101
- DOI
  10.7566/jpscp.33.011101
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05534
[Journal Article] Structural basis for designing an array of engrailed homeodomains2020
- Author(s)
  Sunami Tomoko、Hirano Yu、Tamada Taro、Kono Hidetoshi
- Journal Title
  
  Acta Crystallographica Section D Structural Biology
  
  Volume: 76 Issue: 9 Pages: 824-833
- DOI
  10.1107/s2059798320009237
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05534
[Journal Article] Nucleosome unwrapping and unstacking2020
- Author(s)
  Kono Hidetoshi、Ishida Hisashi
- Journal Title
  
  Current Opinion in Structural Biology
  
  Volume: 64 Pages: 119-125
- DOI
  10.1016/j.sbi.2020.06.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05534, KAKENHI-PROJECT-18K06173
[Journal Article] Heterochromatin protein 1 (HP1): interactions with itself and chromatin components2020
- Author(s)
  Kumar A, *Kono H.
- Journal Title
  
  Biophys Rev
  
  Volume: in press Issue: 2 Pages: 387-400
- DOI
  10.1007/s12551-020-00663-y
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05534
[Journal Article] Structural Studies of Overlapping Dinucleosomes in Solution2020
- Author(s)
  Matsumoto Atsushi、Sugiyama Masaaki、Li Zhenhai、Martel Anne、Porcar Lionel、Inoue Rintaro、Kato Daiki、Osakabe Akihisa、Kurumizaka Hitoshi、Kono Hidetoshi
- Journal Title
  
  Biophysical Journal
  
  Volume: 118 Issue: 9 Pages: 2209-2219
- DOI
  10.1016/j.bpj.2019.12.010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06101, KAKENHI-PROJECT-19KK0071, KAKENHI-PLANNED-18H05534, KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-17H01408
[Journal Article] Balance between DNA‐binding affinity and specificity enables selective recognition of longer target sequences in vivo2019
- Author(s)
  Sunami Tomoko、Kono Hidetoshi
- Journal Title
  
  Protein Science
  
  Volume: 28 Issue: 9 Pages: 1630-1639
- DOI
  10.1002/pro.3677
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05534
[Journal Article] Free energy profile for unwrapping outer superhelical turn of CENP-A nucleosome2019
- Author(s)
  Kono Hidetoshi、Sakuraba Shun、Ishida Hisashi
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 16 Issue: 0 Pages: 337-343
- DOI
  10.2142/biophysico.16.0_337
- NAID
  130007752747
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06173, KAKENHI-PLANNED-18H05534
[Journal Article] Histone H3K23-specific acetylation by MORF is coupled to H3K14 acylation2019
- Author(s)
  Klein BJ, Jang SM, Lachance C, Mi W, Lyu J, Sakuraba S, Krajewski K, Wang WW, Sidoli S, Liu J, Zhang Y, Wang X, Warfield BM, Kueh AJ, Voss AK, Thomas T, Garcia BA, Liu WR, Strahl BD, Kono H, Li W, Shi X, Cote J, Kutateladze TG.
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 12551-12555
- DOI
  10.1038/s41467-019-12551-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534
[Journal Article] Free energy profiles for unwrapping the outer superhelical turn of nucleosomal DNA2018
- Author(s)
  Kono Hidetoshi、Sakuraba Shun、Ishida Hisashi
- Journal Title
  
  PLOS Computational Biology
  
  Volume: 14 Issue: 3 Pages: e1006024-e1006024
- DOI
  10.1371/journal.pcbi.1006024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-25116003
[Journal Article] Investigating the Influence of Arginine Dimethylation on Nucleosome Dynamics Using All-Atom Simulations and Kinetic Analysis2018
- Author(s)
  Li Zhenhai、Kono Hidetoshi
- Journal Title
  
  The Journal of Physical Chemistry B
  
  Volume: 122 Issue: 42 Pages: 9625-9634
- DOI
  10.1021/acs.jpcb.8b05067
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05534
[Journal Article] Genome-wide transcription factor activities are explained by intrinsic conformational dynamics of binding-sites and distal flanking-regions2017
- Author(s)
  Andrabi, M.; Hutchins, A. P.; Miranda-Saavedra, D.; Kono, H.; Nussinov, R.; Mizuguchi, K.; Ahamd, S.
- Journal Title
  
  Scientific Reports
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26330339
[Journal Article] Covalent Modifications of Histone H3K9 Promote Binding of CHD32017
- Author(s)
  Tencer Adam H.、....、Kono Hidetoshi、Poirier Michael G.、Musselman Catherine A.、Kutateladze Tatiana G.
- Journal Title
  
  Cell Reports
  
  Volume: 21 Issue: 2 Pages: 455-466
- DOI
  10.1016/j.celrep.2017.09.054
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25116003
[Journal Article] Predicting conformational ensembles and genome-wide transcription factor binding sites from DNA sequences2017
- Author(s)
  Andrabi Munazah、... 、Kono Hidetoshi、Nussinov Ruth、Mizuguchi Kenji、Ahmad Shandar
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 4071-4071
- DOI
  10.1038/s41598-017-03199-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25116003
[Journal Article] ヌクレオソーム中におけるヒストンテールの特性とアセチル化の影響2017
- Author(s)
  池部仁善; 櫻庭俊; 河野秀俊
- Journal Title
  
  日本生物物理学会誌
  
  Volume: 57 Pages: 095-095
- NAID
  130005509480
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-25116003
[Journal Article] H4 Tails Potentially Produce the Diversity in the Orientation of Two Nucleosomes2017
- Author(s)
  Ishida Hisashi、Kono Hidetoshi
- Journal Title
  
  Biophysical Journal
  
  Volume: 113 Issue: 5 Pages: 978-990
- DOI
  10.1016/j.bpj.2017.07.015
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-25116003
[Journal Article] Accessibility of the histone H3 tail in the nucleosome for binding of paired readers2017
- Author(s)
  Gatchalian Jovylyn、Wang Xiaodong、Ikebe Jinzen、Cox Khan L.、Tencer Adam H.、Zhang Yi、Burge Nathaniel L.、Di Luo、Gibson Matthew D.、Musselman Catherine A.、Poirier Michael G.、Kono Hidetoshi、Hayes Jeffrey J.、Kutateladze Tatiana G.
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 1489-1489
- DOI
  10.1038/s41467-017-01598-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25116003
[Journal Article] Crystal structure of the overlapping dinucleosome composed of hexasome and octasome2017
- Author(s)
  Daiki Kato, Akihisa Osakabe, Yasuhiro Arimura, Yuka Mizukami, Naoki Horikoshi, Kazumi Saikusa, Satoko Akashi, Yoshifumi Nishimura, Sam-Yong Park, Jumpei Nogami, Kazumitsu Maehara, Yasuyuki Ohkawa, Atsushi Matsumoto, Hidetoshi Kono, Rintaro Inoue, Masaaki Sugiyama, Hitoshi Kurumizaka
- Journal Title
  
  Science
  
  Volume: 356 Issue: 6334 Pages: 205-208
- DOI
  10.1126/science.aak9867
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16J06850, KAKENHI-PROJECT-17K07313, KAKENHI-PROJECT-17K19356, KAKENHI-PROJECT-16K18528, KAKENHI-PROJECT-17K15043, KAKENHI-PUBLICLY-16H01306, KAKENHI-PUBLICLY-16H01550, KAKENHI-PUBLICLY-16H01577, KAKENHI-PLANNED-25116002, KAKENHI-PLANNED-25116003, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-15H02042, KAKENHI-PROJECT-17H03608, KAKENHI-PROJECT-16K18479
[Journal Article] H3 histone tail conformation within the nucleosome and the impact of K14 acetylation studied using enhanced sampling simulation2016
- Author(s)
  J. Ikebe, S. Sakuraba and H. Kono,
- Journal Title
  
  PLoS Computational Biology
  
  Volume: 12 Issue: 3 Pages: e1004788-e1004788
- DOI
  10.1371/journal.pcbi.1004788
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-25116003
[Journal Article] Spotting the difference in molecular dynamics simulations of biomolecules2016
- Author(s)
  Sakuraba, S.; Kono, H.
- Journal Title
  
  J. Chem. Phys.
  
  Volume: 145 Issue: 7 Pages: 074116-074116
- DOI
  10.1063/1.4961227
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-25116003
[Journal Article] Distinct Roles of Histone H3 and H2A Tails in Nucleosome Stability2016
- Author(s)
  Li, Z.; Kono, H.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 31437-31437
- DOI
  10.1038/srep31437
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-25116003
[Journal Article] Two arginine residues suppress the flexibility of nucleosomal DNA in the canonical nucleosome core.2015
- Author(s)
  Kono H, Shirayama K, Arimura Y, Tachiwana H, Kurumizaka H.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 3 Pages: e0120635-e0120635
- DOI
  10.1371/journal.pone.0120635
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J03931, KAKENHI-PLANNED-25116002, KAKENHI-PLANNED-25116003
[Journal Article] Intensity of diffracted X-rays from biomolecules with radiation damage caused by strong X-ray pulses2014
- Author(s)
  Kai, T., Tokuhisa, A., Moribayashi, K., Fukuda, Y., Kono, H. & Go, N
- Journal Title
  
  J. Phys. Soc. Jpn.
  
  Volume: 83 Issue: 9 Pages: 094301-094301
- DOI
  10.7566/jpsj.83.094301
- NAID
  210000133248
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-25116003
[Journal Article] Adaptive lambda square dynamics simulation: an efficient conformational sampling method for biomolecules2014
- Author(s)
  Ikebe, J., Sakuraba, S. & Kono, H.
- Journal Title
  
  Journal of Computational Chemistry
  
  Volume: 35 Issue: 1 Pages: 9-50
- DOI
  10.1002/jcc.23462
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-25116003
[Journal Article] Local Dynamics Coupled to Hydration Water Determines DNA-sequence Dependent Deformability2014
- Author(s)
  H. Nakagawa, Y. Yonetani, K. Nakajima, S. Ohira-Kawamura, T.Kikuchi, Y. Inamura, M. Kataoka, H. Kono
- Journal Title
  
  Physical Reiew E
  
  Volume: 90 Issue: 2 Pages: 022723-022723
- DOI
  10.1103/physreve.90.022723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24247030, KAKENHI-PLANNED-25116003
[Journal Article] Local conformational changes in the DNA interfaces of proteins2013
- Author(s)
  Tomoko Sunami, Hidetoshi Kono
- Journal Title
  
  PLoS One
  
  Volume: 8(2) Issue: 2 Pages: e56080-e56080
- DOI
  10.1371/journal.pone.0056080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700354, KAKENHI-PUBLICLY-23114723
[Journal Article] Dissociation Free-Energy Profiles of Specific and Nonspecific DNA-Protein Complexes2013
- Author(s)
  Yonetani, Y. & Kono, H
- Journal Title
  
  J Phys Chem B
  
  Volume: 117 Issue: 25 Pages: 7535-45
- DOI
  10.1021/jp402664w
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-25116003
[Journal Article] What determines water-bridge lifetimes at the surface of DNA? Insight from systematic molecular dynamics analysis of water kinetics for various DNA sequences2012
- Author(s)
  Yonetani, Y., Kono, H.
- Journal Title
  
  Biophysical Chemistry
  
  Volume: 160 Issue: 1 Pages: 54-61
- DOI
  10.1016/j.bpc.2011.09.006
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23114723
[Journal Article] DNAの水和水とダイナミクスの塩基配列依存症-DNA-タンパク質、DNA-低分子認識の理解に向けて-2010
- Author(s)
  米谷佳晃, 河野秀俊
- Journal Title
  
  メディカルバイオ揺らぎと生体機能10月別冊
  
  Pages: 66-71
- Data Source
  KAKENHI-PROJECT-20300103
[Journal Article] Evaluation of DNA Intramolecular Interactions for Nucleosome Positioning in Yeast2009
- Author(s)
  Fernandez, M., Fujii, S., Kono, H., Sarai, A.
- Journal Title
  
  Genome Informatics 23
  
  Pages: 13-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300103
[Journal Article] A Generalized Conformational Energy Function of DNA Derived from Molecular Dynamics Simulations.2009
- Author(s)
  Yamasaki, S., Terada, T., Shimizu, K., Kono, H., Sarai, A.
- Journal Title
  
  Nucleic Acids Res. 37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300103
[Journal Article] Sequence dependencies of DNA deformability and hydration in the minor groove2009
- Author(s)
  Y.Yonetani, H.Kono
- Journal Title
  
  Biophysical Journal 97
  
  Pages: 1138-1147
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21114519
[Journal Article] A Generalized Conformational Energy Function of DNA Derived from Molecular Dynamics Simulations2009
- Author(s)
  Yamasaki S., Terada T., Shimizu K., Kono H., Sarai A.
- Journal Title
  
  Nucleic Acids Res. 37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300103
[Journal Article] Evaluation of DNA Intramolecular Interactions for Nucleosome Positioning in Yeast.2009
- Author(s)
  Fernandez M., Fujii S., Kono H., Sarai, A.
- Journal Title
  
  Genome Informatics 23
  
  Pages: 13-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300103
[Journal Article] Sequence dependencies of DNA deformability and hydration in the minor groove.2009
- Author(s)
  Yonetani Y., Kono H.
- Journal Title
  
  Biophys J 97
  
  Pages: 1138-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300103
[Journal Article] Comparison of DNA hydration patterns obtained using two distinct computational methods, molecular dynamics (MD) simulation and three-dimensional reference interaction site model (3D-RISM) theory2008
- Author(s)
  Yonetani, Y., Maruyama, Y., Hirata, F. and Kono, H.
- Journal Title
  
  J. Chem. Phys. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18031042
[Journal Article] DNA deformability and hydration studied by molecular dynamics simulation.2007
- Author(s)
  Yonetani, Y., Kono, H., Fujii, S., Sarai, A., Go, N.
- Journal Title
  
  Molecular Simulation 33
  
  Pages: 103-107
- Data Source
  KAKENHI-PROJECT-18031042
[Journal Article] 転写制御における協同性の構造メカニズム2007
- Author(s)
  皿井明倫、河野秀俊
- Journal Title
  
  実験医学増刊転写因子による生命現象の統合制御 25
  
  Pages: 77-84
- Data Source
  KAKENHI-PROJECT-18031042
[Journal Article] Sequence-dependent DNA deformability studied using molecular dynamics simulations2007
- Author(s)
  Fujii, S., Kono, H., Takenaka, S., Go, N. and Sarai, A.
- Journal Title
  
  Nucleic Acids Res. 35
  
  Pages: 6063-6074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18031042
[Presentation] The effect of Mg2+ ions on nucleosomal array under external force2023
- Author(s)
  Amarjeet Kumar、Tomoko Sunami、Shoko Sato、Hitoshi Kurumizaka、Hidetoshi Kono
- Organizer
  The 67th Biophysical Society Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] Structure and dynamics of nucleosomes, the fundamental structural unit of chromatin2022
- Author(s)
  Hidetoshi Kono、Jinzen Ikebe、Hisashi Ishida、Shun Sakuraba
- Organizer
  Joint Meeting of the 20th KIAS Conference on Protein Structure and Function and The 7th Korean-Polish Conference on "Protein Folding: Theoretical and Experimental Approaches"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] ヌクレオソームからのH2A-H2B脱離における重要なアミノ酸残基の特定2022
- Author(s)
  石田恒、河野秀俊
- Organizer
  第40回染色体ワークショップ・第21回核ダイナミクス研究会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] Benchmark of force fields to characterize the short intrinsically disordered region of FUS-LC domain2022
- Author(s)
  Maud Chan-Yao-Chong, Justin Chan, Hidetoshi Kono
- Organizer
  第60回日本生物物理学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] Molecular insight into photoactivation mechanism of BLUF protein by QM/MM free energy simulation2022
- Author(s)
  Taguchi M, Sakuraba S, Wai S. Chan, Kono H.
- Organizer
  The 5th International Forum on Quantum Metrology and Sensing
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] NSD2酵素のメチル基付加機構と翻訳後修飾のヌクレオソームに与える影響2022
- Author(s)
  河野秀俊、Kumar Amarjeet、佐藤光、仙石徹
- Organizer
  第45回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] Impact of torque and TF-binding on nucleosome investigated by molecular dynamics simulation and SAXS2022
- Author(s)
  Kono Hidetoshi
- Organizer
  The 2022 (6th) Telluride Workshop on Chromatin Structure and Dynamics
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] 全原子分子動力学シミュレーションを用いた、ヒストンH2A-H2B のヌクレオソームからの脱離メカニズム解析2022
- Author(s)
  石田恒、河野秀俊
- Organizer
  量子生命科学会　第４回大会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] FRET study of the sequence dependence of nucleosomal DNA unwrapping2022
- Author(s)
  Sunami T, Kono H.
- Organizer
  第60回日本生物物理学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] NSD2によるヌクレオソーム上H3 Lys36メチル化の構造基盤2022
- Author(s)
  仙石徹、佐藤光、クマールアマラジート、濱田恵輔、河野秀俊、緒方一博
- Organizer
  第15回日本エピジェネティクス研究会年会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] Building a Coarse-grained Model of Chromatin: Nucleosome-Nucleosome Interaction Patterns2022
- Author(s)
  Chan S. Wai, Kono H.
- Organizer
  量子生命科学会　第４回大会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] ヌクレオソームDNAの配列依存的アンラッピングのFRET解析2022
- Author(s)
  角南智子、河野秀俊
- Organizer
  第22回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] 転写開始点のヌクレオソームDNAアンラッピングのFRET解析2022
- Author(s)
  角南智子、河野秀俊
- Organizer
  量子生命科学会　第４回大会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] ヌクレオソームとその関連タンパク質との相互作用2022
- Author(s)
  河野秀俊
- Organizer
  第22回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] Study on photoactivated enzyme OaPAC by QM/MM molecular simulation2022
- Author(s)
  Taguchi M, Sakuraba S, Wai S. Chan, Kono H.
- Organizer
  第60回日本生物物理学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] 生物物理と計算科学の統合手法による時計タンパク質KaiABC複合体全長の溶液構造の解明2022
- Author(s)
  柚木康弘、松本淳、守島健、マーテルアン、ポーカーリオネル、佐藤信浩、與語理那、富永大輝、井上倫太郎、矢木真穂、奥田綾、清水将裕、裏出令子、寺内一姫、河野秀俊、矢木宏和、加藤晃一、杉山正明
- Organizer
  第22回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] ヌクレオソームDNAのほどけやすさに見られる非対称性2022
- Author(s)
  角南智子、石田恒、河野秀俊
- Organizer
  第45回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] ヌクレオソームからH2A-H2B2量体が脱離する際の自由エネルギー局面解析2022
- Author(s)
  Ishida H, Kono H.
- Organizer
  第60回日本生物物理学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] Building a Coarse-grained Model of Chromatin2022
- Author(s)
  Justin Chan, Hidetoshi Kono
- Organizer
  第60回日本生物物理学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] Benchmark of force fields to characterize the intrinsically disordered region of FUS-LC domain2022
- Author(s)
  Chan-Yao-Chong Maud, Chan S. Wai, Kono H.
- Organizer
  量子生命科学会　第４回大会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] QM/MM 分子シミュレーションによる光活性化酵素 PAC の機能解析2022
- Author(s)
  田口真彦、櫻庭俊、ソオンチワ、河野秀俊
- Organizer
  量子生命科学会　第４回大会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] ヌクレオソーム中のH2A-H2BテイルとDNAの動的相互作用2021
- Author(s)
  大友秀明、栗田順一、櫻庭俊、Zhenhai L.、有村泰宏、若森昌聡、津中康央、梅原崇史、胡桃坂仁志、河野秀俊、西村善文
- Organizer
  第39回染色体ワークショップ・第20回核ダイナミクス研究会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] Catalytic enhancement of NSD2 following oncogenic mutations E1099K and T1150A is caused by increase in the auto-inhibitory loop dynamics2021
- Author(s)
  Kumar A., Sato K., Sakuraba S., Ogata K., Sengoku T., Kono H.
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] 第21回日本中性子科学会年会2021
- Author(s)
  Kono Hidetoshi
- Organizer
  Modeling Protein Complexes by Integrated Approach
- Invited
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] NSD2 によるヌクレオソーム上H3K36メチル化の構造基盤2021
- Author(s)
  仙石徹、佐藤光、クマールアマラジート、濱田恵輔、岡田千佳子、小國麻子、町山歩、櫻庭俊、西澤知宏、濡木理、河野秀俊、緒方一博
- Organizer
  第39回染色体ワークショップ・第20回核ダイナミクス研究会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] NSD2によるヌクレオソーム上H3 Lys36メチル化の構造基盤2021
- Author(s)
  仙石徹、佐藤光、クマールアマラジート、濱田恵輔、岡田千佳子、小國麻子、町山歩、櫻庭俊、西澤知宏、濡木理、河野秀俊、緒方一博
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] Free energy profile of H2A-H2B dimer displacement from nucleosome2021
- Author(s)
  Ishida Hisashi, Kono Hidetoshi
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] Sequence dependence of nucleosomal DNA unwrapping2021
- Author(s)
  Sunami Tomoko, Kono Hidetoshi
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] 転写開始点に特徴的な塩基配列を有するヌクレオソームのFRET解析2021
- Author(s)
  角南智子、河野秀俊
- Organizer
  量子生命科学会第3回大会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] ヌクレオソームにおけるヒストンH2A-H2Bテイルの動的構造2021
- Author(s)
  大友秀明、栗田順一、櫻庭俊、Zhenhai, L.、有村泰宏、若森昌聡、津中康央、梅原崇史、胡桃坂仁志、河野秀俊、西村善文
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] Molecular dynamics simulation of displacement of H2A-H2B from nucleosome2021
- Author(s)
  石田恒、河野秀俊
- Organizer
  量子生命科学会第3回大会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] ヌクレオソームポテンシャルからクロマチンポテンシャル2021
- Author(s)
  河野秀俊
- Organizer
  金沢大学異分野融合セミナー
- Invited
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] Disentangling the Effects of Histone Post-Translational Modifications on Nucleosome Packing and Chromatin Structure2021
- Author(s)
  Chan J., Kono H.
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] ヌクレオソームDNA解離の配列依存性2021
- Author(s)
  角南智子、ルオディ、河野秀俊
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] 中性子散乱データを活用した超分子のモデリング2020
- Author(s)
  河野秀俊
- Organizer
  CBI学会2020大会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] 全原子分子動力学シミュレーションを用いた、ヌクレオソーム安定性に対するねじれストレス影響の解析2020
- Author(s)
  石田恒、河野秀俊
- Organizer
  量子生命科学会　第２回大会
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] Understanding the Dinucleosome Structural Dynamics at All Atom Resolution2020
- Author(s)
  Kumar A, Matsumoto A, Kono H,
- Organizer
  量子生命科学会　第２回大会
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] 相分離への計算科学的アプローチ2020
- Author(s)
  河野秀俊
- Organizer
  第6回蛋白質工学研究会ワークショップ
- Invited
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] 光活性化アデニル酸シクラーゼの量子/古典ハイブリッド分子シミュレーション2020
- Author(s)
  田口真彦、櫻庭俊、チャンワイソオン、河野秀俊
- Organizer
  量子生命科学会　第２回大会
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] Structural basis for an array of engrailed homeodomains toward the development of genome-editing enzymes2020
- Author(s)
  Sunami T, Hirano Y, Tamada T, Kono H,.
- Organizer
  The 58th Annual Meeting of the Biophysics Society of Japan
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] Integrated approach of experimental data and computer modeling and simulation for understanding chromatin structure and dynamics.2019
- Author(s)
  Kono H, Matsumoto A, Sakuraba S, Ishida H.
- Organizer
  第57回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] ヌクレオソームの崩壊と転写2019
- Author(s)
  河野秀俊、Luo D、石田恒
- Organizer
  第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] モデリングとシミュレーションによる生体高分子の構造機能解析2019
- Author(s)
  河野秀俊
- Organizer
  CBI学会2019年大会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] Sequence-Dependent Asymmetric Unwrapping of nucleosomes of yeast2019
- Author(s)
  Luo, D., Kato, D., Nogami, J., Ohkawa, Y., Kurumizaka, H., and Kono, H.
- Organizer
  The 63rd Annual Meeting of the Biophysical Society
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] スーパーコンピュータで知るタンパク質、DNAの形と動き2019
- Author(s)
  河野秀俊
- Organizer
  パコンを知る集い in 岐阜「京」からポスト「京」へ
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] ree energy profiles of the intra- and inter-nucleosomal interactions by all-atom molecular dynamics simulations2018
- Author(s)
  Ishida, H. and Kono, H.
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] スーパーコンピュータでみる分子の形と動き2018
- Author(s)
  河野　秀俊
- Organizer
  一般公開シンポジウム「遺伝子研究の最前線～ミクロの世界に隠された生命の謎にせまる～」
- Data Source
  KAKENHI-ORGANIZER-25116001
[Presentation] Investigating the influence of Argine Dimethylation on Nucleosome Dynamics using All-atom Simulation and Kinetic Analysis2018
- Author(s)
  Li, Z. and Kono, H.
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] Designing an artificial transcription factor with a small molecular weight based on engrailed homeodomain2018
- Author(s)
  Sunami, T. and Kono, H.
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] 核酸―タンパク質相互作用制御2018
- Author(s)
  石田恒; 河野秀俊
- Organizer
  ポスト「京」重点課題１ワークショップ
- Data Source
  KAKENHI-PLANNED-18H05534
[Presentation] Mono- and Di- nucleosome Dynamics Studied by Molecular Modeling and Simulation2018
- Author(s)
  Kono, H.
- Organizer
  The 8th Taiwan-Japan Joint Meeting on Neutron and X-ray Scattering
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] スーパーコンピュータでみる分子の形と動き2018
- Author(s)
  河野秀俊
- Organizer
  一般公開シンポジウム、遺伝子研究の最前線
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] Impact of post-translational modifications on the structure and dynamics of nucleosome2017
- Author(s)
  Kono, H., Luo, D.
- Organizer
  1st QST International Symposium"Quantum Life Science"
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] アセチル化、メチル化によるヒストンH3テールの振る舞いの変化2017
- Author(s)
  河野秀俊; Di, L.; 池部仁善; 櫻庭俊,
- Organizer
  第34回染色体ワークショップ・第15回核ダイナミクス研究会
- Place of Presentation
  千葉・木更津・かずさDNA（国内）
- Year and Date
  2017-01-11
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] Distinct Roles of H3 and H2A tails in linker DNA dynamics.2017
- Author(s)
  Li, Z.; Ikebe, J.; Sakuraba, S.; Kono, H.
- Organizer
  Biophysical Society 61th Annual Meeting
- Place of Presentation
  New Orleans, Louisiana, USA （海外）
- Year and Date
  2017-02-11
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] ヒストンH3翻訳後修飾のヌクレオソーム動態に与える影響2017
- Author(s)
  河野秀俊
- Organizer
  第17回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] Role of tails in intra-nucleosome and inter-nucleosomes.2017
- Author(s)
  Hidetoshi Kono
- Organizer
  HMGU-Japan Epigenetics and Chromatin Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21730
[Presentation] Role of tails in intra-nucleosome and inter-nucleosomes2017
- Author(s)
  Kono, H.
- Organizer
  1st Munche-Japan mini-Symposium,Chromatin Structure and Function
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] ヒストン翻訳後修飾はヌクレオソームの安定性を変える2017
- Author(s)
  河野秀俊
- Organizer
  第40回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] Impact of Post-Translational Modifications on Histone H3 tail on Nucleosome Structure and Dynamics2017
- Author(s)
  Kono, H.
- Organizer
  EMBO Conference: The Nucleosome: From Atoms to Genomes
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] THE FREE-ENERGY LANDSCAPE OF THE DI-NUCLEOSOME: A CRITICAL ROLE OF THE H4 TAILS FOR THE NUCLEOSOME-NUCLEOSOME CONFORMATION.2017
- Author(s)
  Ishida, H.; Kono, H.
- Organizer
  Biophysical Society 61th Annual Meeting
- Place of Presentation
  New Orleans, Louisiana, USA （海外）
- Year and Date
  2017-02-11
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] Free energy analysis of the Nucleosome-Nucleosome interaction analyzed by Biomolecular Simulations2017
- Author(s)
  Ishida, H.; Kono, H.
- Organizer
  1st QST International Symposium"Quantum Life Science"
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] 転写因子のアクティビィティは結合サイト及びその周辺領域のDNA特性の関係できまる2016
- Author(s)
  河野秀俊
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  福岡・福岡・福岡国際会議場（国内）
- Year and Date
  2016-06-07
- Invited
- Data Source
  KAKENHI-PROJECT-26330339
[Presentation] Revisiting DNA conformations in crystal structures2016
- Author(s)
  Sunami, T.; Chatake, T.; Kono, H.
- Organizer
  第54回日本生物物理学会年会
- Place of Presentation
  茨城・つくば・つくば国際会議場　（国内）
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-26330339
[Presentation] Role of histone H3 and H2A tails in nucleosome stability2016
- Author(s)
  Hidetoshi Kono
- Organizer
  Colorado Chromatin Meeting　2016
- Place of Presentation
  USA
- Year and Date
  2016-08-08
- Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21730
[Presentation] セントロメア特異的なクロマチン構造の解析2016
- Author(s)
  鈴木翠; 立名和博昭; 滝沢由政; 松本淳; 河野秀俊; Wolf, M.; 胡桃坂仁志
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  神奈川・横浜・パシフィコ横浜（国内）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] Impact of Histone Variant and Post-translational Modification on Nucleosome2016
- Author(s)
  Kono, H., Ikebe, J., Sakuraba, S. and Ishida, H.
- Organizer
  Biophysical Society 60th Annual Meeting
- Place of Presentation
  Los Angeles Convention Center (Los Angels, CA, USA)
- Year and Date
  2016-02-27
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] 構造多形をもつ生体高分子の全原子モデルの構築2016
- Author(s)
  河野秀俊
- Organizer
  JSBi関西地域部会第21回バイオメディカル研究会
- Place of Presentation
  大阪・大阪・グランフロント大阪　（国内）
- Invited
- Data Source
  KAKENHI-PROJECT-26330339
[Presentation] Role of H3 and H2A Tails on Nucleosome Stability2016
- Author(s)
  Kono, H.
- Organizer
  Colorado Chromatin Meeting 2016
- Place of Presentation
  Colorado State Univ., Colorado, USA （海外）
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] Distinct Roles of Histone H3 and H2A Tails in Nucleosome Stability2016
- Author(s)
  Li, Z.; Kono, H.
- Organizer
  Chromatin Structure & Function, Gordon Conference
- Place of Presentation
  Les Diablerets, Switzerland （海外）
- Year and Date
  2016-05-22
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] 転写因子のアクティビィティは結合サイト及びその周辺領域のDNA特性の関係できまる2016
- Author(s)
  河野秀俊
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  福岡・福岡・福岡国際会議場（国内）
- Year and Date
  2016-06-07
- Invited
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] Distinct roles of histone H3 and H2A tails in nucleosome stability2016
- Author(s)
  Li Zhenhai, Hidetoshi Kono
- Organizer
  Gordon Research Conference, Chromatin Structure & Function
- Place of Presentation
  Switzerland
- Year and Date
  2016-05-24
- Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21730
[Presentation] エングレイルドホメオドメインを用いた新規転写因子設計2016
- Author(s)
  角南智子; 河野秀俊
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  福岡・福岡・福岡国際会議場（国内）
- Year and Date
  2016-06-07
- Data Source
  KAKENHI-PROJECT-26330339
[Presentation] 特殊なヌクレオソームの立体構造解析2016
- Author(s)
  加藤大貴; 越阪部晃永; 足立風水也; 水上優夏; 有村泰宏; 七種和美; 明石知子; 西村善文; 朴三用; 松本淳; 河野秀俊; 井上倫太郎; 杉山正明; 胡桃坂仁志
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  神奈川・横浜・パシフィコ横浜（国内）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] Dynamics of nucleosomes and impact of acetylation2015
- Author(s)
  Kono H, Ikebe J, Sakuraba S, Ishida H.
- Organizer
  International Symposium on Chromatin Structure, Dynamics, and Function
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県淡路市）
- Year and Date
  2015-08-23
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] Differences in Dynamics among Nucleosomes with Distinct Histone Compositions2015
- Author(s)
  Kono, H.
- Organizer
  RIKEN Epigenetics in Kobe
- Place of Presentation
  理研再生科学総合研究センター（神戸）
- Year and Date
  2015-02-14
- Invited
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] Designing a new artificial transcription factor based on engrailed homeodomain2015
- Author(s)
  角南智子、河野秀俊
- Organizer
  第15回日本蛋白質科学会年会
- Place of Presentation
  あわぎんホール（徳島県徳島市）
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-26330339
[Presentation] Designing a new artificial transcription factor based on engrailed homeodomain2015
- Author(s)
  角南智子、河野秀俊
- Organizer
  第38 回日本分子生物学会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26330339
[Presentation] Impact on nucleosome dynamics via histone variants and post-translational modifications2015
- Author(s)
  Kono, H.
- Organizer
  スパコン「京」がひらく科学と社会; Supercomputational Life Science 2015 (SCLS 2015)
- Place of Presentation
  東京大学本郷キャンパス（東京都文京区)
- Year and Date
  2015-10-20
- Invited
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] Role of histone variant and histone tails within the nucleosome and the impact of H3 tail acetylation studied using enhanced sampling simulation2015
- Author(s)
  Ikebe J, Li Z, Sakuraba S, Ishida H, Kono H.
- Organizer
  4th International Symposium of the Mathematics on Chromatin Live Dynamics Hiroshima
- Place of Presentation
  JMSアステールプラザ(広島県広島市)
- Year and Date
  2015-12-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] シミュレーションによる動的クロマチンダイナミクス2014
- Author(s)
  河野秀俊
- Organizer
  分子研研究会「細胞核内反応の分子化学」
- Place of Presentation
  分子研（岡崎）
- Year and Date
  2014-09-27
- Invited
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] ヌクレオソーム中におけるH3ヒストンテイルの構造探索2012
- Author(s)
  池部仁善、河野秀俊
- Organizer
  第30回染色体ワークショップ
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県淡路市）
- Year and Date
  2012-12-20
- Data Source
  KAKENHI-PUBLICLY-23114723
[Presentation] The influence of solvent condition on DNA structures studied by molecular dynamics simulations2012
- Author(s)
  Satoshi Fujii, Hidetoshi Kono, Akinori Sarai
- Organizer
  第50回日本生物物理学会年会
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PLANNED-24118008
[Presentation] A New Method for Evaluating the Specificity of Indirect Readout in Protein-DNA Recognition2012
- Author(s)
  S. Yamasaki, T. Terada, H. Kono, K. Shimizu, A. Sarai
- Organizer
  European Conference on Computational Biology
- Place of Presentation
  Basel, Switzerland
- Data Source
  KAKENHI-PLANNED-24118008
[Presentation] Molecular Dynamics of Nucleosome Core Particles2012
- Author(s)
  河野秀俊
- Organizer
  The 2nd International Workshop on Structural Epigenomics
- Place of Presentation
  理研横浜研究所交流棟ホール（神奈川県横浜市）
- Year and Date
  2012-10-10
- Invited
- Data Source
  KAKENHI-PUBLICLY-23114723
[Presentation] ヒストンタンパク質の違いによるヌクレオソームコアパーティクルの安定性とダイナミクスの違い2012
- Author(s)
  河野秀俊
- Organizer
  第85回日本生化学大会
- Place of Presentation
  福岡国際会議場(福岡県福岡市）
- Year and Date
  2012-12-15
- Invited
- Data Source
  KAKENHI-PUBLICLY-23114723
[Presentation] ヌクレオソームがスライドするときの自由エネルギー地形2011
- Author(s)
  金枝直子、石田恒、河野秀俊
- Organizer
  日本物理学会秋季大会
- Place of Presentation
  富山
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PUBLICLY-23114723
[Presentation] Molecular Dynamics Simulation of CENP-A Containing Nucleosome2011
- Author(s)
  Kono, H.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜(招待講演)
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PUBLICLY-23114723
[Presentation] シミュレーション計算による核内DNA-タンパク質複合体の機能発現メカニズム2011
- Author(s)
  河野秀俊
- Organizer
  バイオスーパーコンピューティング研究会
- Place of Presentation
  和光(招待講演)
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PUBLICLY-23114723
[Presentation] Free energy profiles for nucleosome position changes2011
- Author(s)
  Kono, H., Kanaeda, N., Ishida, H.
- Organizer
  Biophysical Society Annual Meeting
- Place of Presentation
  米国、ボルチモア
- Year and Date
  2011-03-06
- Data Source
  KAKENHI-PUBLICLY-21114519
[Presentation] Free energy profiles for nucleosome position changes2011
- Author(s)
  Kono, H., Kanaeda, N., Ishida, H.
- Organizer
  Biophysical Society Annual Meeting
- Place of Presentation
  米国、ボルチモア
- Year and Date
  2011-03-06
- Data Source
  KAKENHI-PROJECT-20300103
[Presentation] 核内DNA-protein複合体のダイナミクスと分子機能2011
- Author(s)
  河野秀俊
- Organizer
  日本物理学会秋季大会
- Place of Presentation
  富山(招待講演)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PUBLICLY-23114723
[Presentation] Free energy profile of nucleosomal DNA sliding2011
- Author(s)
  Kanaeda, N., Ishida, H., Kono, H.
- Organizer
  日本生物物理学会年会
- Place of Presentation
  姫路
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PUBLICLY-23114723
[Presentation] Free energy profiles for nucleosome position changes.2011
- Author(s)
  Kono H., Kanaeda N., Ishida H.
- Organizer
  55th Biophysical Society Annual Meeting
- Place of Presentation
  Baltimore, USA
- Data Source
  KAKENHI-PROJECT-20300103
[Presentation] シミュレーションからみるタンパク質-核酸の分子認識機構2011
- Author(s)
  河野秀俊
- Organizer
  第四回JSBi応用システムバイオロジー研究会/第一回「細胞環境の測定とモデリング」ワークショップ
- Place of Presentation
  神戸(招待講演)
- Year and Date
  2011-11-07
- Data Source
  KAKENHI-PUBLICLY-23114723
[Presentation] 構造バイオインフォマティクスと分子動力学計算による遺伝子発現制御メカニズムの理解2010
- Author(s)
  河野秀俊
- Organizer
  第33回日本分子生物学会年会第83回日本生科学会大会合同大会
- Place of Presentation
  神戸(招待講演)
- Data Source
  KAKENHI-PROJECT-20300103
[Presentation] 情報エントロピーを用いたタンパク質-DNA認識におけるindirect readoutの寄与の評価2010
- Author(s)
  山崎智,河野秀俊,清水謙多郎,皿井明倫,寺田透
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20300103
[Presentation] ヌクレオソームポジションにおける間接認識の役割2010
- Author(s)
  Fernandez M.,藤井聡,河野秀俊,皿井明倫
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20300103
[Presentation] ヌクレオソームコアパーテクルの自由エネルギープロファイル計算2010
- Author(s)
  金枝直子, 河野秀俊
- Organizer
  第27回染色体ワークショップ
- Place of Presentation
  静岡県御殿場
- Year and Date
  2010-01-22
- Data Source
  KAKENHI-PUBLICLY-21114519
[Presentation] ヌクレオソームDNAがスライドする時の自由エネルギープロファイル2010
- Author(s)
  金枝直子, 石田恒, 河野秀俊
- Organizer
  日本生物物理学会年会
- Place of Presentation
  仙台
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PUBLICLY-21114519
[Presentation] 構造バイオインフォマティクスと分子動力学計算による遺伝子発現制御メカニズムの理解2010
- Author(s)
  河野秀俊
- Organizer
  日本分子生物学会年会、日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PUBLICLY-21114519
[Presentation] ヌクレオソームポジションにおける間接認識の役割2010
- Author(s)
  Fernandez, M., 藤井聡, 河野秀俊, 皿井明倫
- Organizer
  日本蛋白質科学会年会
- Place of Presentation
  札幌
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-20300103
[Presentation] 情報エントロピーを用いたタンパク質-DNA認識におけるindirect readoutの寄与の評価2010
- Author(s)
  山崎智, 河野秀俊, et al.
- Organizer
  日本蛋白質科学会年会
- Place of Presentation
  札幌
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-21651087
[Presentation] 構造バイオインフォマティクスと分子動力学計算による遺伝子発現制御メカニズムの理解2010
- Author(s)
  河野秀俊
- Organizer
  日本分子生物学会年会、日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20300103
[Presentation] Sequence dependencies of DNA deformability and hydration in the minor groove2009
- Author(s)
  Y.Yonetani, H.Kono
- Organizer
  Algorithms in Macromolecular Modeling Conference(AM3)
- Place of Presentation
  米国、テキサス大学オースティン校
- Year and Date
  2009-11-12
- Data Source
  KAKENHI-PUBLICLY-21114519
[Presentation] Structure-based Analysis of Cooperativity in Protein-DNA Recognition2009
- Author(s)
  Tanaka A., Fujii S., Kono H., Sarai A.
- Organizer
  第47回日本生物物理学会年会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-20300103
[Presentation] The free energy profile of a nucleosome core particle through the molecular dynamics simulation2009
- Author(s)
  N.Kanaeda, H.Ishida, H.Kono
- Organizer
  第47回日本生物物理学会年会
- Place of Presentation
  徳島
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PUBLICLY-21114519
[Presentation] Evaluation of DNA Intramolecular Interactions for Nucleosome Positioning in Yeast.2009
- Author(s)
  Fernandez, M., Fujii, S., Kono, H., Sarai, A.
- Organizer
  The 20th International Conference on Genome Informatics.
- Place of Presentation
  横浜
- Year and Date
  2009-12-16
- Data Source
  KAKENHI-PROJECT-20300103
[Presentation] The free energy profile of a nucleosome core particle through the molecular dynamics simulation2009
- Author(s)
  N.Kanaeda, H.Ishida, H.Kono
- Organizer
  第47回日本生物物理学会年会
- Place of Presentation
  徳島
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-20300103
[Presentation] Role of indirect readout in protein-DNA recognition assessed by a Bayesian approach2009
- Author(s)
  Yamasaki S., Fukui K., Kono H., Shimizu K., Sarai A., Terada T.
- Organizer
  第47回日本生物物理学会年会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-20300103
[Presentation] タンパク質-DNA相互作用の認識塩基配列と非認識塩基配列による違い2008
- Author(s)
  徳久淳師,河野秀俊
- Organizer
  第8回日本蛋白質科学会年会
- Place of Presentation
  東京(日本)
- Data Source
  KAKENHI-PROJECT-20300103
[Presentation] DNAの柔らかさの塩基配列依存性と水和の関係2007
- Author(s)
  米谷佳晃、藤井聡、皿井明倫、河野秀俊、郷信広
- Organizer
  日本生物物理学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18031042
[Presentation] DNA structural study under ethanol/water mixture based on molecular dynamics simulations
- Author(s)
  Satoshi Fujii, Hidetoshi Kono
- Organizer
  第41回国際核酸化学シンポジウム
- Place of Presentation
  北九州国際会議場、福岡市
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PLANNED-24118008
[Presentation] Free Energy Profile for Nucleosomal DNA Unwrapping
- Author(s)
  Kono, H., Yonetani, Y., Ikebe, J., Sakuraba, S. & Ishida, H.
- Organizer
  第51回日本生物物理学会年会
- Place of Presentation
  京都国際会館、京都
- Invited
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] Free Energy Profile for Nucleosomal DNA Unwrapping
- Author(s)
  Kono, H., Sakuraba, S. & Ishida, H.
- Organizer
  Biophysical Society 59th Annual Meeting
- Place of Presentation
  米国　ボルチモア
- Year and Date
  2015-02-07 – 2015-02-11
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] Adaptive lambda square dynamics simulation: an efficient conformational sampling method for biomolecules
- Author(s)
  Ikebe, J., Sakuraba, S. & Kono, H.
- Organizer
  Biophysical Society 58th Annual Meeting
- Place of Presentation
  San Francisco、米国
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] Conformational sampling of unmodified and acetylated H3 histone tails on a nucleosome by all-atom model molecular dynamics simulations
- Author(s)
  Ikebe, J., Sakuraba, S. & Kono, H.
- Organizer
  Biophysical Society 59th Annual Meeting
- Place of Presentation
  米国　ボルチモア
- Year and Date
  2015-02-07 – 2015-02-11
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] H3ヒストンテールの構造とダイナミクス
- Author(s)
  河野秀俊、池部仁善
- Organizer
  第31回染色体ワークショップ・第12回核ダイナミクス研究会
- Place of Presentation
  ホテルおかだ、神奈川
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] CENP-Aヌクレオソーム特異的なDNA構造の構造生物学的・生化学的解析
- Author(s)
  Shirayama, K., Arimura, Y., Tachiwana, H., Kono, H. & Kurumizaka, H.
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜、横浜
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] ヌクレオソームにおけるH3ヒストンテールの構造アンサンブル
- Author(s)
  河野秀俊、池部仁善
- Organizer
  第14回日本蛋白質科学学会年会
- Place of Presentation
  ワークピア横浜（横浜）
- Year and Date
  2014-06-25 – 2014-06-27
- Invited
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] Designing a new artificial transcription factor based on engrailed homeodomain
- Author(s)
  角南智子、河野秀俊
- Organizer
  第52回日本生物物理学会年会
- Place of Presentation
  札幌コンベンションセンター(札幌)
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26330339
[Presentation] CENP-A ヌクレオソームにおける動的なDNA構造とその制御機構
- Author(s)
  Arimura, Y., Osakabe, A., Shirayama, K., Takeda, Y., Miya, Y., Tachiwana, H., Kono, H. & Kurumizaka, H.
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場、神戸
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] DISSOCIATION FREE-ENERGY PROFILES OF SPECIFIC AND NON-SPECIFIC DNA-LACREPRESSOR COMPLEXES:ADAPTIVE BIASINGFORCE MOLECULAR DYNAMICS STUDY
- Author(s)
  Kono, H. & Yonetani, Y.
- Organizer
  Biophysical Society 58th Annual Meeting
- Place of Presentation
  San Francisco、米国
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] 生体分子MDの間違い探し
- Author(s)
  櫻庭俊、河野秀俊
- Organizer
  第28回分子シミュレーション討論会
- Place of Presentation
  市民会館（仙台）
- Year and Date
  2014-11-12 – 2014-11-14
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] Understanding Protein-DNA Recognition by Structural Bioinformatics and Molecular Dynamics Simulation
- Author(s)
  Kono, H.
- Organizer
  Second BMIRC International Symposium on Advances in Bioinformatics and Medical Engineering
- Place of Presentation
  Center of Iizuka Research and Development, Iizuka, Fukuoka
- Invited
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] 立体構造から探るタンパク質-DNA 認識機構
- Author(s)
  河野秀俊
- Organizer
  2013 年年会生命医薬情報学連合大会
- Place of Presentation
  タワーホール船堀、東京
- Invited
- Data Source
  KAKENHI-PLANNED-25116003
[Presentation] Adaptive lambda square dynamics simulation: an efficient conformational sampling method for biomolecules
- Author(s)
  Ikebe, J., Sakuraba, S. & Kono, H.
- Organizer
  第51回日本生物物理学会年会
- Place of Presentation
  京都国際会館、京都
- Data Source
  KAKENHI-PLANNED-25116003

1. Kurumizaka Hitoshi (80300870)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. KIMURA Hiroshi (30241392)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. OBUSE Chikashi (00273855)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HARAGUCHI Tokuko (20359079)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. YONEDA Yoshihiro (80191667)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TOKUNAGA Makio (00192659)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. SAITOH Noriko (40398235)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. OHKAWA Yasuyuki (80448430)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. HARATA Masahiko (70218642)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 皿井明倫 (20221286)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
11. MATSUMOTO Atsushi (10399420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. SUNAMI Tomoko (50554648)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
13. NAKAMURA Haruki (80134485)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KAMIYA Narutoshi (80420462)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KASAHARA Kota (90634965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 緒方一博 (90260330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KIM Thi Phuong Oanh (90370387)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 中川洋 (20379598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 米谷佳晃 (80399419)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
20. 藤井聡 (40452825)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
21. 杉山正明 (10253395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
22. LI Zhenhai

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
23. IIDA Midori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 斎藤稔

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 森井尚之

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. GROMIHA Mich

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. HIGO Junichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 片岡幹雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kono Hidetoshi 河野 秀俊

KONO Hidetoshi 河野 秀俊

河野 秀俊 コウノ ヒデトシ

Research Projects

Research Products

Co-Researchers

Elucidation of chromatin potential through the analysis of nucleosome structure and dynamics

Principal Investigator

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International research network for chromatin structure, dynamics, and function

Principal Investigator

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Improvement of sequence specificity of DNA-binding protein using computational and experimental approachesPrincipal Investigator

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Chromatin dynamics analysis using computer simulationPrincipal Investigator

Principal Investigator

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Chromatin structure, dynamics, and function

Principal Investigator

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Research Institution

Elucidation of information-processing mechanisms during transcription cycle using computational and information sciences

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ヌクレオソーム構造の自由エネルギープロファイル解析Principal Investigator

Principal Investigator

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シミュレーション計算によるヌクレオソーム構造形成の自由エネルギー地形解析Principal Investigator

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DNA配列に特異的に結合するタンパク質分子設計Principal Investigator

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Regulation of Gene Transcription Inferred From Transcription Factor Binding and Nucleosome PositioningPrincipal Investigator

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中性子散乱実験と分子動力学計算による蛋白質-DNA認識機構における水の挙動解析Principal Investigator

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Research Institution

転写因子のターゲット部位予側にもとづく遺伝子の機能及び相互作用推定Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

転写因子のターゲット部位予側からのゲノム機能推定Principal Investigator

Principal Investigator

Kono Hidetoshi 河野秀俊

KONO Hidetoshi 河野秀俊

河野秀俊コウノヒデトシ