YAMAKI Akiko 八巻明子

… Alternative Names

八巻明子ヤマキアキコ

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Researcher Number	40296546
Other IDs
External Links
Affiliation (Current)	2025: 杏林大学, 保健学部, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 杏林大学, 保健学部, 准教授 2008 – 2009: Kyorin University, 保健学部, 講師 2007: 杏林大, 保健学部, 講師 2006: 杏林大学, 保健学部, 講師 2002 – 2004: 杏林大学, 保健学部, 助手 1998 – 1999: 杏林大学, 保健学部, 助手
Review Section/Research Field	Principal Investigator Embryonic/Neonatal medicine / Basic Section 59020:Sports sciences-related / Human genetics Except Principal Investigator Embryonic/Neonatal medicine / Urology
Keywords	Principal Investigator プロモーター / SIM2 / 転写因子 / ダウン症候群 / 運動負荷 / 抗酸化能力 / 酸化ストレス / 有酸素運動 / プロモーター解析 / SIM遺伝子 … More / SIM2_s / SIM2_L / ダウン症 / MyoD / NF1 / HIF / ゲルシフトアッヤイ / SIM2遺伝子 / GFP融合蛋白質 / 核移行シグナル / single-minded / Down syndrome / 2量体形成 / トランスジェニックマウス / ARNT2 / ARNT / ルシフェラーゼ活性 / 欠失変異体 / GFP / ゲルシフトアッセイ / cis-エレメント / プロモーター領域 / 転写開始点 / Sim2遺伝子 … More Except Principal Investigator DYRK1A / MNB / DSCR4 / SIM2 / デイファレンシャルデイスプレイ法 / target gene / ubiquitination / nuclear localization signal / Regulation of transcription / Down Syndrome / CpGアイランドメチル化 / 定量RT-PCR / 恒常発現細胞 / CpGアイランドのメチル化 / ARNT2 / 標的遺伝子 / ユビキチン化 / 核移行シグナル / 転写調節 / ダウン症 / differential display method / FISH mapping / cloning of kidney cyst-related genes / human genome BAC library / PKDI mutation / DNA diagnosis / polycystic kidney disease / ヒトゲノムBACライブラリースクリーニング / デファレンシャルデイスプレイ法 / FISHマッピング / 腎嚢胞形成関連遺伝子クローニング / ヒトゲノムBACライブラリー / PKD1変異解析 / DNA診断 / 多発性嚢胞腎 Less

Effects of different doses of antioxidants(Vitamin E) intake on exercise induced oxidative stress, antioxidative capacity and chronic inflammationPrincipal Investigator
- Principal Investigator
  
  八巻明子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Kyorin University
Analysis of SIM gene expression and SIM protein interaction in Down SyndromePrincipal Investigator
- Principal Investigator
  
  YAMAKI Akiko
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Kyorin University
ダウン症発症における21番染色体q22.2領域ヒトSIM2遺伝子の関与Principal Investigator
- Principal Investigator
  
  八巻明子
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Kyorin University
Regulation of expression and funcional analysis of Down syndrome gene
- Principal Investigator
  
  SHIMIZU Yoshiko
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Kyorin University
ヒトマウスSim2遺伝子の発現調節機構とダウン症精神遅滞Principal Investigator
- Principal Investigator
  
  八巻明子
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Human genetics
- Research Institution
  Kyorin University
Development of DNA diagnosis method of polycystic kidney disease and cloning of genes related to the formation of kidney cysts
- Principal Investigator
  
  SHIMIZU Yoshiko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  KYORIN UNIVERSITY

All 2023 2008 2007 2006 2005 2004 2001

All Journal Article Presentation

[Journal Article] Analysis of the promoter region of human placenta-specific DSCR4 gene2008
- Author(s)
  Satoko Asai, Akiko Yamaki, Jun Kudoh, Nobuyoshi Shimizu, Yoshiko Shimizu
- Journal Title
  
  Biochimica et Biophysica Acta 1779
  
  Pages: 40-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790766
[Journal Article] Analysis of the promoter region of human placenta-specific DSCR4 gene.2008
- Author(s)
  Satoko Asai, Akiko Yamaki, Jun Kudoh, Nobuyoshi Shimizu, Yoshiko Shimizu
- Journal Title
  
  Biochemica et Biophysica Acta. 1779
  
  Pages: 40-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790766
[Journal Article] ダウン症関連遺伝子DSCR4の発現解析2005
- Author(s)
  浅井聡子, 清水元, 八巻明子, 松田貴雄, 清水淑子
- Journal Title
  
  杏林医学会雑誌 36・1(印刷中)
- NAID
  110002702815
- Data Source
  KAKENHI-PROJECT-15790557
[Journal Article] Expression analysis of DSCR4 gene located on Down syndrome chromosomal region2005
- Author(s)
  Asai, S., Shimizu, H., Yamaki, A., Matuda, T., Shimizu, Y.
- Journal Title
  
  J.Kyorin Med.Soc.(in Japanese) 36
  
  Pages: 32-41
- NAID
  110002702815
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370323
[Journal Article] Transcription factor single-minded 2 (SIM2) is ubiquitinated by the RING-IBR-RING-type E3 ubiquitin ligases2005
- Author(s)
  Okui M., Yamaki A, Takayanagi A, Kudoh J, Shimizu N, Shimizu Y
- Journal Title
  
  Exp Cell Res (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370323
[Journal Article] Transcription Factor Single-Minded 2 (SIM2) is ubiquitinated by the RING-IBR-RING-type E3 ubiquitin ligases2005
- Author(s)
  Okui, M., Yamaki, A., Takayanagi, A., Kudoh, J., Shimizu, N., Shimizu, Y.
- Journal Title
  
  Exp.Cell Res. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370323
[Journal Article] ダウン症関連遺伝子DSCR4の発現解析2005
- Author(s)
  浅井聡子, 清水元, 八巻明子, 松田貴雄, 清水淑子
- Journal Title
  
  杏林医会誌 36
  
  Pages: 32-41
- NAID
  110002702815
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370323
[Journal Article] ダウン症関連遺伝子DSCR4の発現解析2005
- Author(s)
  浅井聡子, 清水元, 八巻明子, 松田貴雄, 清水淑子
- Journal Title
  
  杏林医学会雑誌 36・1(印刷中)
- NAID
  110002702815
- Data Source
  KAKENHI-PROJECT-14370323
[Journal Article] A novel nuclear localization signal in the human single-minded proteins SIM1 and SIM22004
- Author(s)
  Yamaki A, Kudoh J, Shimizu N, Shimizu Y
- Journal Title
  
  Biochem Biophys Res Commun 313・3
  
  Pages: 482-488
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370323
[Journal Article] A novel nuclear localization signal in the human single-minded proteins SIM1 and SIM22004
- Author(s)
  A Yamaki, J Kudoh, N Shimizu, Y Shimizu
- Journal Title
  
  Biochem Biophys Res Commum 313・3
  
  Pages: 482-488
- Data Source
  KAKENHI-PROJECT-14370323
[Journal Article] A novel nuclear localization signal in the human single-minded proteins SIM1 and SIM22004
- Author(s)
  A Yamaki, J Kudoh, N Shimizu, Y Shimizu
- Journal Title
  
  Biochem Biophys Res Commun 313・3
  
  Pages: 482-488
- Data Source
  KAKENHI-PROJECT-15790557
[Journal Article] A novel nuclear localization signal in the human single-minded proteins SIM1 and SIM22004
- Author(s)
  Yamaki, A., Kudoh, J., Shimizu, N., Shimizu, Y.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 313
  
  Pages: 482-488
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370323
[Journal Article] Molecular mechanisms of human single-minded 2 (SIM2) gene expression : Identification of a promoter site in the SIM22001
- Author(s)
  Yamaki, A., Tochigi, J., Kudoh, J., Minoshima, S., Shimizu, N., Shimizu, Y.
- Journal Title
  
  Genomic Sequence, Gene 270
  
  Pages: 265-275
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370323
[Journal Article] Molecular mechanisms of human single-minded 2 (SIM2) gene expression : Identification of a promoter site in the SIM2 genomic sequence2001
- Author(s)
  Yamaki A, Tochigi J, Kudoh J, Minoshima S, Shimizu N, Shimizu Y
- Journal Title
  
  GENE 270
  
  Pages: 265-275
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370323
[Presentation] Acute effects of maximal graded exercise test on cardiac autonomic nervous activity and arterial baroreceptor reflex function in endurance athletes2023
- Author(s)
  鈴木里奈、八巻明子、平吹一訓、旗典孝、福家真理那、植地貴弘、平澤愛、松田剛明、柴田茂貴
- Organizer
  Europian college of sport science
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11609
[Presentation] bHLH-PASファミリー転写因子のSIM2は体内時計タンパク質BMAL1と相互作用する2007
- Author(s)
  清水淑子、八巻明子, ら
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18790766
[Presentation] ダウン症関連遺伝子タンパク質SIM2と体内時計タンパク質BMAL1との相互作用2007
- Author(s)
  清水淑子、八巻明子, ら
- Organizer
  第14回日本遺伝子診療学会大会
- Place of Presentation
  愛媛
- Data Source
  KAKENHI-PROJECT-18790766
[Presentation] bHLH-PASファミリー転写因子SIM1、SIM2は体内時計タンパク質BMAL1と相互作用する2007
- Author(s)
  清水淑子、八巻明子、池田正明、工藤純、清水信義
- Organizer
  第30回日本分子生物学会年会、第80回日本生化学会年会(ポスター発表)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18790766
[Presentation] Molecular interaction of single-minded (SIM) proteins with Aryl hydrocarbon receptor translocator (ARNT) proteins.2006
- Author(s)
  Akiko Yamaki, et al.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-18790766
[Presentation] Hyaluronan synthetase 2 is a target gene of human SIM2 transcription factor2006
- Author(s)
  Y. Shimizu, A. Yamaki, et al.
- Organizer
  56th Annual Meeting ASHG
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-18790766
[Presentation] Hyaluronan synthetase 2 as a target gene of human SIM22006
- Author(s)
  Y. Shimizu, A. Yamaki, et al.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-18790766
[Presentation] ヒトSIM2転写調節遺伝子はHAS2遺伝子の発現を調節する2006
- Author(s)
  清水淑子、八巻明子, ら
- Organizer
  第13回日本遺伝子診療学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18790766

1. SHIMIZU Yoshiko (50255410)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. TAMURA Takashi (70146554)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. HIGASHIBARA Eiji (00092312)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KUDOH Jun (80178003)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. MATSUDA Takao (10304825)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 柴田茂貴 (90636474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

YAMAKI Akiko 八巻 明子

八巻 明子 ヤマキ アキコ

Research Projects

Research Products

Co-Researchers

Effects of different doses of antioxidants(Vitamin E) intake on exercise induced oxidative stress, antioxidative capacity and chronic inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of SIM gene expression and SIM protein interaction in Down SyndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ダウン症発症における21番染色体q22.2領域ヒトSIM2遺伝子の関与Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of expression and funcional analysis of Down syndrome gene

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒトマウスSim2遺伝子の発現調節機構とダウン症精神遅滞Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of DNA diagnosis method of polycystic kidney disease and cloning of genes related to the formation of kidney cysts

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Analysis of the promoter region of human placenta-specific DSCR4 gene2008

Author(s)

Journal Title

Data Source

[Journal Article] Analysis of the promoter region of human placenta-specific DSCR4 gene.2008

Author(s)

Journal Title

Data Source

[Journal Article] ダウン症関連遺伝子DSCR4の発現解析2005

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Expression analysis of DSCR4 gene located on Down syndrome chromosomal region2005

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Transcription factor single-minded 2 (SIM2) is ubiquitinated by the RING-IBR-RING-type E3 ubiquitin ligases2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Transcription Factor Single-Minded 2 (SIM2) is ubiquitinated by the RING-IBR-RING-type E3 ubiquitin ligases2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] ダウン症関連遺伝子DSCR4の発現解析2005

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] ダウン症関連遺伝子DSCR4の発現解析2005

Author(s)

Journal Title

NAID

YAMAKI Akiko 八巻明子

八巻明子ヤマキアキコ