Nakagawa Kazuhiko 中川和彦

… Alternative Names

NAKAGAWA Kazuhiko 中川和彦

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Researcher Number	40298964
Other IDs
Affiliation (Current)	2025: 近畿大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2009 – 2016: 近畿大学, 医学部, 教授 2007: Kinki University, School of Medicine, Professor 2004 – 2006: 近畿大学, 医学部, 助教授
Review Section/Research Field	Except Principal Investigator Clinical oncology / Respiratory organ internal medicine / Tumor therapeutics
Keywords	Except Principal Investigator 分子標的治療 / EGFR / HER2 / ゲフィチニブ / gefitinib / 化学療法 / 分子標的薬 / 胃癌 / 非小細胞肺癌 / 臨床腫瘍学 … More / PGI2 / PEG2. / meloxicum / NSCLC / PGE2 / COX2阻害剤 / メロキシカム / IGFR-1 / mutation / chemotherapy / non-small cell cancer / Lung Cancer / シスプラチン / カルボプラチン / パクリタキセル / イリノテカン / 局所進行肺がん / 放射線化学療法 / インスリン様成長因子I受容体 / 上皮成長因子受容体 / インシュリン増殖因子受容体1 / 遺伝子変異 / 上皮成長因子受容体(EGFR) / 非小細胞がん / 肺がん / heregulin / 血漿検体 / SKBR-3 / N87 / cfDNA BC / WJOG7212G / 西日本がん研究機構 / ヘレギュリン / 薬剤耐性 / 乳癌 / Resistance / MET / Gastric Cancer / MET遺伝子増幅 / EML4-ALK融合遺伝子 / EGFR遺伝子変異 / ゲフィニチブ / 腫瘍治療学 / EML4-ALK / 肺癌 / 癌 / 呼吸器感染症 / 肺線維症 / 非閉塞性肺疾患 Less

A biomarker study of heregulin to predict efficacy of anti-HER2 drugs in HER2-positive breast and gastric cancer
- Principal Investigator
  
  TSURUTANI Junji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kindai University
Multiplex molecular profiling in advanced non-small cell lung cancers
- Principal Investigator
  
  OKAMOTO Isamu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical oncology
- Research Institution
  Kyushu University
  Kinki University
Antitumor Action of the MET Tyrosine Kinase Inhibitor in Gastric Cancer Positive for MET Amplification
- Principal Investigator
  
  OKAMOTO Wataru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical oncology
- Research Institution
  National Cancer Center Japan
  Kinki University
EML4-ALK陽性肺癌におけるシグナル伝達経路の解析
- Principal Investigator
  
  宮崎昌樹
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical oncology
- Research Institution
  Kinki University
Role of survivin in EGFR inhibitor-induced apoptosis in non-small cell lung cancers positive for EGFR mutations.
- Principal Investigator
  
  OKAMOTO Kunio
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical oncology
- Research Institution
  Kinki University
Molecular-based approach for overcoming acquired resistance to EGFR tyrosine kinase inhibitors
- Principal Investigator
  
  OKAMOTO Isamu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kinki University
Translational research for recurrent lung cancer treatment with combination therapy of gefitinib and meloxicam
- Principal Investigator
  
  SATOH Taroh
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kinki University
A randomized study to evaluate survival benefit of gefitinib in patients with advanced non-small cell lung cancer and correlation of efficacy and biomarkers
- Principal Investigator
  
  FUKUOKA Masahiro
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kinki University

All 2019 2018 2017 2016 2014 2013 2012 2011 2010 2007 2006 2005 2004 Other

All Journal Article Presentation

[Journal Article] [fam‐] trastuzumab deruxtecan, antitumor activity is dependent on HER2 expression level rather than on HER2 amplification2019
- Author(s)
  Takegawa Naoki、Tsurutani Junji、Kawakami Hisato、Yonesaka Kimio、Kato Ryoji、Haratani Koji、Hayashi Hidetoshi、Takeda Masayuki、Nonagase Yoshikane、Maenishi Osamu、Nakagawa Kazuhiko
- Journal Title
  
  International Journal of Cancer
  
  Volume: 145 Issue: 12 Pages: 3414-3424
- DOI
  10.1002/ijc.32408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11730, KAKENHI-PROJECT-26430174
[Journal Article] Targeting of the HER2/HER3 signaling axis overcomes ligand-mediated resistance to trastuzumab in HER2-positive breast cancer2019
- Author(s)
  Satomi Watanabe, Kimio Yonesaka, Junko Tanizaki, Yoshikane Nonagase, Naoki Takegawa, Koji Haratani, Hisato Kawakami, Hidetoshi Hayashi, Masayuki Takeda, Junji Tsurutani, Kazuhiko Nakagawa
- Journal Title
  
  Cancer Medicine
  
  Volume: 8 Issue: 3 Pages: 1258-1268
- DOI
  10.1002/cam4.1995
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26430174
[Journal Article] Mutational activation of the epidermal growth factor receptor down-regulates major histocompatibility complex class I expression via the extracellular signal-regulated kinase in non-small cell lung cancer2018
- Author(s)
  Satomi Watanabe, Hidetoshi Hayashi, Koji Haratani, Shigeki Shimizu, Junko Tanizaki, Kazuko Sakai, Hisato Kawakami, Kimio Yonesaka, Junji Tsurutani, Yosuke Togashi, Kazuto Nishio, Akihiko Ito, Kazuhiko Nakagawa
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 1 Pages: 52-60
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26430174
[Journal Article] HER2 genomic amplification in circulating tumor DNA and estrogen receptor positivity predict primary resistance to trastuzumab emtansine (T-DM1) in patients with HER2-positive metastatic breast cancer.2018
- Author(s)
  Sakai H, Tsurutani J, Iwasa T, Komoike Y, Sakai K, Nishio K, Nakagawa K.
- Journal Title
  
  Breast Cancer
  
  Volume: 25(5) Issue: 5 Pages: 605-613
- DOI
  10.1007/s12282-018-0861-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-26430174
[Journal Article] DS-8201a, a new HER2-targeting antibody-drug conjugate incorporating a novel DNA topoisomerase I inhibitor, overcomes HER2-positive gastric cancer T-DM1 resistance2017
- Author(s)
  Naoki Takegawa, Yoshikane Nonagase, Kimio Yonesaka, Kazuko Sakai, Osamu Maenishi, Yusuke Ogitani, Takao Tamura, Kazuto Nishio, Kazuhiko Nakagawa, Junji Tsurutani
- Journal Title
  
  International Journal of Cancer
  
  Volume: 141 Issue: 8 Pages: 1682-1689
- DOI
  10.1002/ijc.30870
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26430174
[Journal Article] HER2 genomic amplification in circulating tumor DNA from patients with cetuximab-resistant colorectal cancer2016
- Author(s)
  Naoki Takegawa, Kimio Yonesaka, Kazuko Sakai, Hiroto Ueda, Satomi Watanabe, Yoshikane Nonagase, Tatsuya Okuno, Masayuki Takeda, Osamu Maenishi, Junji Tsurutani, Taroh Satoh, Isamu Okamoto, Kazuto Nishio, Takao Tamura, Kazuhiko Nakagawa
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 3 Pages: 3453-3460
- DOI
  10.18632/oncotarget.6498
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26430174
[Journal Article] Heregulin-expressing HER2-positive breast and gastric cancer exhibited heterogeneous susceptibility to the anti-HER2 agents lapatinib, trastuzumab and T-DM1.2016
- Author(s)
  Nonagase Y, Yonesaka K, Kawakami H, Watanabe S, Haratani K, Takahama T, Takegawa N, Ueda H, Tanizaki J, Hayashi H, Yoshida T, Takeda M, Chiba Y, Tamura T, Nakagawa K, Tsurutani J.
- Journal Title
  
  Oncotarget
  
  Volume: 20;7(51) Issue: 51 Pages: 84860-84871
- DOI
  10.18632/oncotarget.12743
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430174
[Journal Article] Survival outcome assessed according to tumor response and shrinkage pattern in patients with EGFR mutation-positive non-small cell lung cancer treated with gefitinib or erlotinib.2014
- Author(s)
  Takeda K, Okamoto I (Correspondence author), Nakagawa K
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 9(2) Pages: 200-204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501359
[Journal Article] Multiplex genomic profiling of non–small cell lung cancers from the LETS phase III trial of first-line S-1/carboplatin versus paclitaxel/carboplatin: results of a West Japan Oncology Group study2014
- Author(s)
  Okamoto I, Sakai K, Morita S, Yoshioka H, Kaneda H, Takeda K, Hirashima T, Kogure Y, Kimura T, Takahashi T, Atagi S, Seto T, Sawa T, Yamamoto M, Satouchi M, Okuno M, Nagase S, Takayama K, Tomii K, Maeda T, Oizumi S, Fujii S, Akashi Y, Nishino K, Ebi N, Nakagawa K, Nakanishi Y, Nishio K.
- Journal Title
  
  Oncotarget
  
  Volume: 5 Pages: 2293-2304
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24501359
[Journal Article] Targeting MET Amplification as a New Oncogenic Driver.2014
- Author(s)
  Kawakami H, Okamoto I, Okamoto W, Tanizaki J, Nakagawa K, Nishio K.
- Journal Title
  
  Cancers(Basel)
  
  Volume: 6(3) Issue: 3 Pages: 1540-52
- DOI
  10.3390/cancers6031540
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24240122, KAKENHI-PROJECT-24501359, KAKENHI-PROJECT-24501360
[Journal Article] MET amplification as a potential therapeutic target in gastric cancer.2013
- Author(s)
  Kawakami H, Okamoto I, Arao T, Okamoto W, Matsumoto K, Taniguchi H, Kuwata K, Yamaguchi H, Nishio K, Nakagawa K, Yamada Y.
- Journal Title
  
  Oncotarget
  
  Volume: 4(1) Pages: 9-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501360
[Journal Article] A novel mass spectrometry–based assay for diagnosis of EML4-ALK–positive non–small cell lung cancer.2012
- Author(s)
  Sakai K, Okamoto I, Takezawa K, Hirashima T, Kaneda H, Takeda M, Matsumoto K, Kimura H, Fujita Y, Nakagawa K, Arao T, Nishio K.
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 7 Pages: 913-918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501359
[Journal Article] Association of the expression of mutant EGFR protein as determined with mutation-specific antibodies in non-small cell lung cancer with progression-free survival after gefitinib treatment2012
- Author(s)
  Azuma K, Okamoto I, Kawahara A, Taira T, Nakashima K, Hattori S, KinoshitaT, Takeda M, Nakagawa K, Takamori S, Kuwano M, Ono M, KageM
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 7 Pages: 122-127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Phase I clinical study of the angiogenesis inhibitor TSU-68 combined with carboplatin and paclitaxel in chemotherapy-naive patients with advanced non-small cell lung cancer2012
- Author(s)
  Okamoto I, Yoshioka H, Takeda K, Satouchi M, Yamamoto N, Seto T, Kasahara K, Miyazaki M, Kitamura R, Ohyama A, Hokoda N, Nakayama H, Yoshihara E, Nakagawa K
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 7 Pages: 427-433
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Overcoming erlotinib resistance in EGFR mutation-positive non-small cell lung cancer cells by targeting survivin2012
- Author(s)
  Okamoto K, Okamoto I, Hatashita E, Kuwata K, Yamaguchi H, Kita A, Yamanaka K, Ono M, Nakagawa K
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 11(1) Pages: 204-213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501316
[Journal Article] Clinical Phase I Study of Elpamotide, a Peptide Vaccine for VEGFR 2, in Patients with Advanced Solid Tumors2012
- Author(s)
  Okamoto I, Arao T, Miyazaki M, Satoh T, Okamoto K, Tsunoda T, Nishio K, Nakagawa K
- Journal Title
  
  Cancer Science
  
  Volume: 103(12) Pages: 2135-2138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501316
[Journal Article] Clinical Outcome of Thoracic Radiotherapy for Locally Advanced NSCLC with EGFR Mutations or EML4-ALK.2012
- Author(s)
  Hayashi H, Okamoto I, Kimura H, Sakai K, Nishimura Y, Nishio K, Nakagawa K.
- Journal Title
  
  Anticancer Research
  
  Volume: 32(10) Pages: 4533-4537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501359
[Journal Article] Overcoming Erlotinib Resistance in EGFR Mutation-Positive Non-Small Cell Lung Cancer Cells by Targeting SurvivinMolecular2012
- Author(s)
  Okamoto K, Okamoto I, Hatashita E, Kuwata K, Yamaguchi H, Kita A, Yamanaka K, Ono M, Nakagawa K
- Journal Title
  
  Cancer Therapeutics
  
  Volume: 11 Pages: 204-213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] EML4-ALK-targeted therapy for advanced non-small cell lung cancer: molecular and clinical aspects.2012
- Author(s)
  Okamoto I, Nakagawa K
- Journal Title
  
  Cancer Science
  
  Volume: 103(8) Pages: 1391-1396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501359
[Journal Article] Combined effect of ALK and MEK inhibitor in EML4-ALK-positive non-small-cell lung cancer cells2012
- Author(s)
  Tanizaki J, Okamoto I, Takezawa K, Sakai K, Azuma K, Kuwata K, Yamaguchi H, Hatashita E, Nishio K, Janne PA, Nakagawa K
- Journal Title
  
  British Journal of Cancer
  
  Volume: 106 Pages: 763-767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Clinical outcome for EML4-ALK–positive patients with advanced non–small cell lung cancer treated with first-line platinum-based chemotherapy.2012
- Author(s)
  Takeda M, Okamoto I, Sakai K, Kawakami K, Nishio K, Nakagawa K.
- Journal Title
  
  Annals of Oncology
  
  Volume: 23(11) Pages: 2931-2936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501359
[Journal Article] Marked response to both S-1 and pemetrexed in a patient with echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase-positive lung adenocarcinoma.2012
- Author(s)
  Kaneda H, Okamoto I, Sakai K, Tanizaki J, Takeda M, Nishio K, Nakagawa K.
- Journal Title
  
  Acta Oncologica
  
  Volume: 51(7) Pages: 942-944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501359
[Journal Article] Antitumor action of the MET tyrosine kinase inhibitor crizotinib (PF-02341066) in gastric cancer positive for MET amplification.2012
- Author(s)
  Okamoto W, Okamoto I, Arao T, Kuwata K, Hatashita E, Yamaguchi H, Sakai K, Yanagihara K, Nishio K, Nakagawa K.
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 11(7) Pages: 1557-1564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501360
[Journal Article] Clinical phase I study of elpamotide, a peptide vaccine for vascular endothelial growth factor receptor 2, in patients with advanced solid tumors.2012
- Author(s)
  Okamoto I, Arao T, Miyazaki M, Satoh T, Okamoto K, Tsunoda T, Nishio K, Nakagawa K.
- Journal Title
  
  Cancer Sci
  
  Volume: 103(12) Pages: 2135-2138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501316
[Journal Article] Activation of HER family signaling as a mechanism of acquired resistance to ALK inhibitors in EML4-ALK-positive non-small cell lung cancer.2012
- Author(s)
  Tanizaki J, Okamoto I, Okabe T, Sakai K, Tanaka K, Hayashi H, Kaneda H, Takezawa K, Kuwata K, Yamaguchi H, Hatashita E, Nishio K, Nakagawa K.
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 18(22) Pages: 6219-6226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501359
[Journal Article] Feasibility study of two schedules of sunitinib in combination with pemetrexed in patients with advanced solid tumors2012
- Author(s)
  Okamoto I, Shimizu T, Miyazaki M, Tsurutani J, Ichikawa Y, Terashima M, Takeda M, Fumita S, Ohki E, Kimura N, Hashimoto J, Nakagawa K
- Journal Title
  
  Investigational New Drugs
  
  Volume: 30 Pages: 639-646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Roles of BIM induction and survivin down-regulation in lapatinib-induced apoptosis in breast cancer cells with HER2 amplification2011
- Author(s)
  Tanizaki J, Okamoto I, Fumita S, Okamoto W, Nishio K, Nakagawa K
- Journal Title
  
  Oncogene
  
  Volume: 30 Pages: 4097-4106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Single-agent gefitinib with concurrent radiotherapy for locally advanced non-small cell lung cancer harboring mutations of the epidermal growth factor receptor2011
- Author(s)
  Okamoto I, Takahashi T, Okamoto H, Nakagawa K, Watanabe K, Nakamatsu K, Nishimura Y, Fukuoka M, Yamamoto N
- Journal Title
  
  Lung Cancer
  
  Volume: 72(1) Pages: 199-204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab2011
- Author(s)
  Yonesaka K, Zejnullahu K, Okamoto I, Satoh T, Cappuzzo F, Souglakos J, Ercan D, Rogers A, Roncalli M, Takeda M, FujisakaY, Philips J, Shimizu T, Maenishi O, Cho Y, Sun J, Destro A, Taira K, Takeda K, OkabeT, Swanson J, Itoh H, Takada M, Lifshits E, Okuno K, Engelman A J, Shivdasani A R, Nishio K, Fukuoka M, Garcia V M, Nakagawa K, and Janne A. P
- Journal Title
  
  Science Translation Medicine
  
  Volume: 3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Role of ERK-BIM and STAT3-survivin signaling pathways in ALK inhibitor-induced apoptosis in EML4-ALK-positive lung cancer2011
- Author(s)
  Takezawa K, Okamoto I, Nishio K, Janne P, Nakagawa K
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 17(8) Pages: 2140-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Thymidylate synthase and dihydropyrimidine dehydrogenase expression levels are associated with response to S-1 plus carboplatin in advanced non-small cell lung cancer2011
- Author(s)
  Takeda M, Okamoto I, Hirabayashi N, Kitano M, Nakagawa K
- Journal Title
  
  Lung Cancer
  
  Volume: 73(1) Pages: 103-109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Differential roles of trans-phosphorylated EGFR, HER2, HER3, and RET as heterodimerisation partners of MET in lung cancer with MET amplification2011
- Author(s)
  Tanizaki J, Okamoto I, Sakai K, Nakagawa K
- Journal Title
  
  British Journal of Cancer
  
  Volume: 105 Pages: 807-813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Differential roles of STAT3 depending on the mechanism of STAT3 activation in gastric cancer cells2011
- Author(s)
  Okamoto W, Okamoto I, Arao T, Yanagihara K, Nishio K, Nakagawa K
- Journal Title
  
  British Journal of Cancer
  
  Volume: 105(3) Pages: 407-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] MET Tyrosine Kinase Inhibitor Crizotinib (PF-02341066) Shows Differential Antitumor Effects in Non-small Cell Lung Cancer According to MET Alterations2011
- Author(s)
  Tanizaki J, Okamoto I, Okamoto K, Takezawa K, Kuwata K, Yamaguchi H, Nakagawa K
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 6(10) Pages: 1624-1631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501316
[Journal Article] MET Tyrosine Kinase Inhibitor Crizotinib(PF-02341066) Shows Differential Antitumor Effects in Non-small Cell Lung Cancer According to MET Alterations2011
- Author(s)
  Tanizaki J, Okamoto I, Okamoto K, Takezawa K, Kuwata K, Yamaguchi H, Nakagawa K
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 10 Pages: 1624-1634
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] High-dose dexamethasone plus antihistamine prevents colorectal cancer patients treated with modified FOLFOX6 from hypersensitivity reactions induced by oxaliplatinHigh-dose dexamethasone plus antihistamine prevents colorectal cancer patients treated with modified FOLFOX6 from hypersensitivity reactions induced by oxaliplatin2011
- Author(s)
  Kidera Y, Satoh T, Ueda S, Okamoto W, Okamoto I, Fumita S, Yonesaka K, Hayashi H, Makimura C, Okamoto K, Kiyota H, Tsurutani J, Miyazaki M, Yoshinaga M, Fujiwara K, Yamazoe Y, Moriyama K, Tsubaki M, Chiba Y, Nishida S, Nakagawa K
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 16(3) Pages: 244-249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501316
[Journal Article] Tymidylate synthase as a determinant of pemetrexed sensitivity in non-small cell lung cancer2011
- Author(s)
  Takezawa K, Okamoto I, Okamoto W, Takeda M, Sakai K, Tsukioka S, Kuwata K, Yamaguchi H, Nishio K, Nakagawa K
- Journal Title
  
  British Journal of Cancer
  
  Volume: 104(10) Pages: 1594-601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Phase I Safety, Pharmacokinetic, and Biomarker Study of BIBF 1120, an Oral Triple Tyrosine Kinase Inhibitor in Patients with Advanced Solid Tumors2010
- Author(s)
  Okamoto I, Kaneda H, Satoh T, Okamoto W, Miyazaki M, Morinaga R, Ueda S, Terashima M, Tsuya A, Sarashina A, Konishi K, Arao T, Nishio K, Kaiser R, Nakagawa K
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 9(10) Pages: 2825-2833
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Identification of c-Src as a potential therapeutic target for gastric cancer and of MET activation as a cause of resistance to c-Src inhibition2010
- Author(s)
  Okamoto W, Okamoto I, Yoshida T, Okamoto K, Takezawa K, Hatashita E, Yamada Y, Kuwata K, Arao T, Yanagihara K, Fukuoka M, Nishio K, Nakagawa K
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 9(5) Pages: 1188-1197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Identification of thymidylate synthase as a potential therapeutic target for lung cancer2010
- Author(s)
  Takezawa K, Okamoto I, Tsukioka S, Uchida J, Kiniwa M, Fukuoka M, Nakagawa K
- Journal Title
  
  British Journal of Cancer
  
  Volume: 103(3) Pages: 354-361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Role of survivin in EGFR inhibitor-induced apoptosis in non-small cell lung cancers positive for EGFR mutations2010
- Author(s)
  Okamoto K, Okamoto I, Okamoto W, Tanaka K, Takezawa K, Kuwata K, Yamaguchi H, Nishio K, Nakagawa K
- Journal Title
  
  Cancer Research
  
  Volume: 70(24) Pages: 10402-10410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] TAK-701, a humanized monoclonal antibody to HGF, reverses gefitinib resistance induced by tumor-derived HGF in non-small cell lung cancer with an EGFR mutation2010
- Author(s)
  Okamoto W, Okamoto I, Tanaka K, Hatashita E, Yamada Y, Kuwata K, Yamaguchi H, Arao T, Nishio K, Fukuoka M, Janne PA, Nakagawa K
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 9(10) Pages: 2785-2792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Does escalation study of pemetrexed in combination with carboplatin followed by pemetrexed maintenance therapy for advanced non-small cell lung cancer2010
- Author(s)
  Okamoto I, Takeda K, Daga H, Miyazaki M, Yonesaka K, Kiyota H, Tsurutani J, Ueda S, Ichikawa Y, Takeda M, Sekiguchi R, Tominaga K, Enatsu S, Nambu Y, Nakagawa K
- Journal Title
  
  Lung Cancer
  
  Volume: 70(2) Pages: 168-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Phase I clinical and pharmacokinetic study of sorafenib in combination with carboplatin and paclitaxel in patients with advanced non-small cell lung cancer2010
- Author(s)
  Okamoto I, Miyazaki M, Morinaga R, Kaneda H, Ueda S, Hasegawa Y, Satoh T, Kawada A, Fukuoka M, Fukino K, Tanigawa T, Nakagawa K
- Journal Title
  
  Investigational New Drugs
  
  Volume: 28(6) Pages: 844-853
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] The emerging role of epidermal growth factor receptor(EGFR) inhibitors in first-line treatment for patients with advanced non-small cell lung cancer positive for EGFR mutations2010
- Author(s)
  Okamoto I. Mitsudomi T, Nakagawa K, Fukuoka M
- Journal Title
  
  Therapeutic Advences in Medical Oncology
  
  Volume: 2(5) Pages: 301-307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Enhanced anticancer effect of the combination of BIBW2992 and thymidylate synthase-targeted agents in non-small cell lung cancer with the T790M mutation of epidermal growth factor receptor2010
- Author(s)
  Takezawa K, Okamoto I, Tanizaki J, Kuwata K, Yamaguchi H, Fukuoka M, Nishio K, Nakagawa K
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 9(6) Pages: 1647-1656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Phase I Clinical and Pharmacokinetic Study of RAD001(Everolimus) Administered Daily to Japanese Patients with Advanced Solid Tumors2010
- Author(s)
  Okamoto I, Doi T, Ohtsu A, Miyazaki M, Tsuya A, Kurei K, Kobayashi K, Nakagawa K
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 40(1) Pages: 17-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Synergistic antitumor effect of S-1 and HER2-targeting agents in gastric cancer with HER2 amplification2010
- Author(s)
  Tanizaki J, Okamoto I, Takezawa K, Tsukioka S, Uchida J, Kiniwa M, Fukuoka M, Nakagawa K
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 9(5) Pages: 1198-1207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Marked anti-tumour activity of the combination of YM155, a novel survivin suppressant, and platinum-based drugs2010
- Author(s)
  Iwasa T, Okamoto I, Takezawa K, Yamanaka K, Nakahara T, Kita A, Koutoku H, Sasamata M, Hatashita E, Yamada Y, Kuwata K, Fukuoka M, Nakagawa K
- Journal Title
  
  British Journal of Cancer
  
  Volume: 103(1) Pages: 36-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Randomized, open-label, phase III, noninferiority trial comparing oral S-1 plus carboplatin with paclitaxel plus carboplatin in chemotherapy-naive patients with advanced non-small cell lung cancer : results of a West Japan Oncology Group(LETS) study2010
- Author(s)
  Okamoto I, Yoshioka H, Morita S, Ando M, Takeda K, Seto T, Yamamoto N, Saka H, Asami K, Hirashima T, Kudoh S, Satouchi M, Ikeda N, Iwamoto Y, Sawa T, Miyazaki M, Tamura K, Kurata K, Fukuoka M, Nakagawa K
- Journal Title
  
  Journal of Clinical Oncology
  
  Volume: 28(36) Pages: 5240-5246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Successful treatment with erlotinib after gefitinib-induced severe interstitial lung disease2010
- Author(s)
  Takeda M, Okamoto I, Makimura C, Fukuoka M, Nakagawa K
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 5(7) Pages: 1103-1104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Disturbance of the Growth Hormone-Insulin-like Growth Factor-1 Axis Associated with Poor Performance Status in Patients with Solid Tumors2010
- Author(s)
  Okamoto I, Munakata M, Miyazaki M, Satoh T, Takahata T, Takamatsu Y, Muto O, Koike K, Ishitani K, Mukaiyama T, Sakata Y, Nakagawa K, Tamura K
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 40(3) Pages: 222-226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591011
[Journal Article] Randomized phase III study of cisplatin plus irinotecan versus carb oplatin plus paclitaxel, cisplatin plus gemcitabine, and cisplatin plus vinorelbine for advanced non-small-cell lung cancer : Four-Arm Cooperative Study in Japan.2007
- Author(s)
  Ohe Y., Ohashi Y., Kubota K., Tamura T., Nakagawa K., Negoro S., Nishiwaki Y., Saijo N., Ariyoshi Y., Fukuoka M.
- Journal Title
  
  Ann. Oncol. 18(2)
  
  Pages: 317-323
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Randomized phase III study of cisplatin plus irinotecan versus carboplatin plus paclitaxel, cisplatin plus gemcitabine, and cisplatinplus vinorelbine for advanced non-small-cell lung cancer : Four-Arm Cooperative Study in Japan.2007
- Author(s)
  Ohe Y, Ohashi Y, Kubota K, Tamura T, Nakagawa K, Negoro S, Nishiwaki Y, Saijo N, Ariyoshi Y, Fukuoka M.
- Journal Title
  
  ann. Oncol. 18(2)
  
  Pages: 317-23
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Randomized phase III study of cisplatin plus irinotecan versus carboplatin plus paclitaxel, cisplatin plus gemcitabine, and cisplatin plus vinorelbine for advanced non-small-cell lung cancer : Four-Arm Cooperative Study in Japan.2007
- Author(s)
  Ohe Y., Ohashi Y., Kubota K., Tamura T., Nakagawa K., Negoro S., Nishiwaki Y., Saijo N., Ariyoshi Y., Fukuoka M
- Journal Title
  
  Ann.Oncol. 18(2)
  
  Pages: 317-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Phase II study of weekly paclitaxel for Relapsed and refractory small cell lung cancer.2006
- Author(s)
  Yamamoto N, Tsurutani J, Yoshimura N, Asai G, Moriyama A, Nakagawa K, Kudou S, Takada M, Minato Y, Fukuoka M.
- Journal Title
  
  Anticancer Res 26
  
  Pages: 777-781
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] EGFR mutation in gefitinib-responsive small-cell lung cancer.2006
- Author(s)
  Okamoto I, Araki J, Suto R, Shimada M, Nakagawa K, Fukuoka M.
- Journal Title
  
  Ann Oncol 17
  
  Pages: 1028-1029
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Phase I and Pharmacokinetic Study of Combination Chemotherapy Using Irinotecan and paclitaxel in Patients with Lung Cancer.2006
- Author(s)
  Asai, G, Yamamoto, N, Kurata, T, Tamura, K, Uejima, H, Nakagawa, K, Fukuoka, M.
- Journal Title
  
  J Thorac Oncol. 1
  
  Pages: 226-230
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] A phase I study of pemetrexed (LY231514) supplemented with folate and vitamin B12 in Japanese patients with solid tumours.2006
- Author(s)
  Nakagawa K., Kudoh S., Matsui K., Negoro S., Yamamoto N., Latz J.E., Adachi S., Fukuoka M.
- Journal Title
  
  Br.J.Cancer 95
  
  Pages: 677-682
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Phase III study of docetaxel compared with vinorelbine in elderly patients with advanced non-small-cell lung cancer : results of the West Japan Thoracic Oncology Group Trial (WJTOG 9904)2006
- Author(s)
  Kudoh S, Takeda K, Nakagawa K, Takada M, Katakami N, Matsui K, Shinkai T, Sawa T, Goto I, Semba H, Seto T, Ando M, Satoh T, Yoshimura N, Negoro S, Fukuoka M
- Journal Title
  
  J Clin Oncol 24
  
  Pages: 3657-3663
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Is the Importance of Achieving Stable Disease Different between Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors and Cytotoxic Agents in the Second-Line Setting for Advanced Non-small Cell Lung Cancer?2006
- Author(s)
  Kurata T., Matsuo K., Takada M., Kawahara M., Tsuji M., Matsubara Y., Otani N., Matsuyama S., Muraishi K., Fujita T., Ishikawa M., Koyano K., Okamoto I., Satoh T., Tamura K., Nakagawa K., Fukuoka M.
- Journal Title
  
  Journal of Thoracic Oncology 1
  
  Pages: 684-691
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Phase II Study of Etoposide and Cisplatin With Concurrent Twice-Daily Thoracic Radiotherapy Followed by Irinotecan and Cisplatin in Patients With Limited-Disease Small-Cell Lung Cancer2006
- Author(s)
  Saito H, Takada Y, Ichinose Y, Eguchi K, Kudoh S, Matsui K, Nakagawa K, Takada M, Negoro S, Tamura K, Ando M, Tada T, Fukuoka M
- Journal Title
  
  J Clin Oncol. 24(33)
  
  Pages: 5247-5252
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Small interfering RNA targeting survivin sensitizes lung cancer cell with mutant p53 to adriamycin2006
- Author(s)
  Yonesaka, K., Tamura, K., Kurata, T., Satoh, T., Ikeda, M., Fukuoka, M., Nakagawa, K.
- Journal Title
  
  Int J Cancer 118
  
  Pages: 812-820
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] A Phase I Study of Irinotecan in Combination with Amrubicin for Advanced Lung Cancer Patients.2006
- Author(s)
  Kaneda, H, Kurata, T, Tamura, K, Uejima, H, Nakagawa, K, Fukuoka, M.
- Journal Title
  
  Anticancer Res. 26
  
  Pages: 2479-2486
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] A phase I study of pemetrexed (LY231514) supplemented with folate and vitamin B12 in Japanese patients with solid tumours.2006
- Author(s)
  Nakagawa K, Kudoh S, Matsui K, Negoro S, Yamamoto N, Latz J. E, Adachi S, Fukuoka M.
- Journal Title
  
  Br. J. Cancer 95
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] EKB-569, a new irreversible epidermal growth factor receptor tyrosine kinase inhibitor, with clinical activity in patients with non-small cell lung cancer with acquired resistance to gefitinib.2006
- Author(s)
  Yoshimura N., Kudoh S., Kimura T., Mitsuoka S., Matsuura K., Hirata K., Matsui K., Negoro S., Nakagawa K.Fukuoka M.
- Journal Title
  
  Lung Cancer 51
  
  Pages: 363-368
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Phase I and Pharmacokinetic Study of Combination Chemotherapy Using Irinotecan and paclitaxel in Patients with Lung Cancer.2006
- Author(s)
  Asai, G., Yamamoto, N., Kurata, T., Tamura, K., Uejima, H., Nakagawa, K., Fukuoka, M.
- Journal Title
  
  J Thorac Oncol. 1
  
  Pages: 226-230
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Pemetrexed-induced edema of the eyelid.2006
- Author(s)
  Kurata T., Tamura K., Okamoto I., Satoh T., Nakagawa K., Fukuoka M.
- Journal Title
  
  Lung Cancer 54
  
  Pages: 241-242
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Randomized Phase II study of Carboplatin/Gemcitabine versus Vinorelbine/Gemcitabine in Patients With Advanced Non small Cell Lung Cancer. West Japan Thoracic Oncology Group(WJTOG) 0104.2006
- Author(s)
  Yamamoto N, Nakagawa K, Uejima H, Sugiura T, Takada Y, Negoro S, Matsui K, Kashii T, Takada M, Nakanishi Y, Kato T, Fukuoka M..
- Journal Title
  
  Cancer 107
  
  Pages: 599-605
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Phase I and Pharmacokinetic Study of Combination Chemotherapy Using Irinotecan and paclitaxel in Patients with Lung Cancer.2006
- Author(s)
  Asai, G., Yamamoto, N., Kurata, T., Tamura, K., Uejima, H., Nakagawa, K., Fukuoka, M.
- Journal Title
  
  J Thorac Oncol. (1)
  
  Pages: 226-230
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Randomized Phase II study of Carboplatin/Gemcitabine versus Vinorelbine/Gemcitabine in Patients With Advanced Non small Cell Lung Cancer. West Japan Thoracic Oncology Group(WJTOG) 0104.2006
- Author(s)
  Yamamoto N., Nakagawa K., Uejima H., Sugiura T., Takada Y., Negoro S., Matsui K., Kashii T., Takada M., Nakanishi Y., Kato T., Fukuoka M.
- Journal Title
  
  Cancer 107
  
  Pages: 599-605
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Phase II study of weekly paclitaxel for Relapsed and refractory small cell lung cancer.2006
- Author(s)
  Yamamoto N, Tsurutani J, Yoshimura N, Asai G, Moriyama A, Nakagawa K, Kudou S, Takada M, Minato Y, Fukuoka M.
- Journal Title
  
  Anticancer Res. 26
  
  Pages: 777-781
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Phase III study of docetaxel compared with vinorelbine in elderly patients with advanced non-small-cell lung cancer : results of the West Japan Thoracic Oncology Group Trial (WJTOG 9904)2006
- Author(s)
  Kudoh S, takeda K, Nakagawa K, Takada M, Katakami N, Matsui K, Shinkai T, Sawa T, Goto I, Semba H, Seto T, ando M, Satoh T, Yoshimura N, Negoro S, Fukuoka M
- Journal Title
  
  J Clin Oncol 24
  
  Pages: 3657-3663
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Is the Importance of Achieving Stable Disease Different between Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors and Cytotoxic Agents in the Second-Line Setting for Advanced Non-small Cell Lung Cancer?2006
- Author(s)
  Kurata T, Matsuo K, Takada M, Kawahara M, Tsuji M, Matsubara Y, Otani N, Matsuyama S, Muraishi K, Fujita T, Ishikawa M, Koyano K, Okamoto I, Satoh T, Tamura K, Nakagawa K, Fukuoka M.
- Journal Title
  
  Journal of Thoracic Oncology 1
  
  Pages: 684-691
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Small interfering RNA targeting survivin sensitizes lung cancer cell with mutant p53 to adriamycin.2006
- Author(s)
  Yonesaka K, Tamura K, Kurata T, Satoh T, Ikeda M, Fukuoka M, Nakagawa K.
- Journal Title
  
  Int J Cancer 118
  
  Pages: 812-820
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Phase II Study of Etoposide and Cisplatin With Concurrent Twice-Daily Thoracic Radiotherapy Followed by Irinotecan and Cisplatin in Patients With Limited- Disease Small-Cell Lung Cancer : West Japan Thoracic Oncology Group 9902.2006
- Author(s)
  Saito H, Takada Y, Ichinose Y, Eguchi K, Kudoh S, Matsui K, Nakagawa K, Takada M, Negoro S, Tamura K, Ando M, Tada T, Fukuoka M.
- Journal Title
  
  J Clin Oncol. 24(33)
  
  Pages: 5247-5252
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] A EGFR mutation in gefitinib-responsive small-cell lung cancer.2006
- Author(s)
  Okamoto I, Araki J, Suto R, Shimada M, Nakagawa K, Fukuoka M.
- Journal Title
  
  Ann Oncol. 17
  
  Pages: 1028-1029
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Pemetrexed-induced edema of the eyelid.2006
- Author(s)
  Kurata T, Tamura K, Okamoto I, Satoh T, Nakagawa K, Fukuoka M.
- Journal Title
  
  Lung Cancer 54
  
  Pages: 241-242
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] A Phase I Study of Irinotecan in Combination with Amrubicin for Advanced Lung Cancer Patients.2006
- Author(s)
  Kaneda, H., Kurata, T., Tamura, K., Uejima, H., Nakagawa, K., Fukuoka, M.
- Journal Title
  
  Anticancer Res. 26
  
  Pages: 2479-2486
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Phase III study of docetaxel compared with vinorelbine in elderly patients with advanced non-small-cell lung cancer : results of the West Japan Thoracic Oncology Group Trial (WJTOG 9904).2006
- Author(s)
  Kudoh S, Takeda K, Nakagawa K, Takada M, Katakami N, Matsui K, Shinkai T, Sawa T, Goto I, Semba H, Seto T, Ando M, Satoh T, Yoshimura N, Negoro S, Fukuoka M.
- Journal Title
  
  J Clin Oncol 24
  
  Pages: 3657-3663
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] EKB-569, a new irreversible epidermal growth factor receptor tyrosine kinase inhibitor, with clinical activity in patients with non-small cell lung cancer with acquired resistance to gefitinib.2006
- Author(s)
  Yoshimura N., Kudoh S., Kimura T., Mitsuoka S., Matsuura K., Hirata K., Matsui K., Negoro S., Nakagawa K., Fukuoka M.
- Journal Title
  
  Lung Cancer 51
  
  Pages: 363-368
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] A EGFR mutation in gefitinib-responsive small-cell lung cancer.2006
- Author(s)
  Okamoto I, Araki J, Suto R, Shimada M, Nakagawa K, Fukuoka M
- Journal Title
  
  Ann Oncol. 17
  
  Pages: 1028-1029
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] EKB-569, a new irreversible epidermal growth factor receptor tyrosine kinase inhibitor, with clinical activity in patients with non-small cell lung cancer with acquired resistance to gefitinib.2006
- Author(s)
  Yoshimura N, Kudoh S, Kimura T, Mitsuoka S, Matsuura K, Hirata K, Matsui K, Negoro S, Nakagawa K, Fukuoka M.
- Journal Title
  
  Lung Cancer 51
  
  Pages: 363-368
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Small interfering RNA targeting survivin sensitizes lung cancer cell with mutant p53 to adriamycin.2006
- Author(s)
  Yonesaka K, Tamura K, Kurata T, Satoh T, Ikeda M, Fukuoka M, Nakagawa K.
- Journal Title
  
  Int J Cancer. 118
  
  Pages: 812-820
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Phase II study of weekly paclitaxel for Relapsed and refractory small cell lung cancer.2006
- Author(s)
  Yamamoto N, Tsurutani J, Yoshimura N, Asai G, Moriyama A, Nakagawa K, Kudou S, Takada M, Minato Y, Fukuoka M
- Journal Title
  
  Anticancer Res. 26
  
  Pages: 777-781
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] A phase I study of pemetrexed (LY231514) supplemented with folate and vitamin B12 in Japanese patients with solid tumours.2006
- Author(s)
  Nakagawa K., Kudoh S., Matsui K., Negoro S., Yamamoto N., Latz J.E., Adachi S., Fukuoka M.
- Journal Title
  
  Br. J. Cancer 95
  
  Pages: 677-682
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Small interfering RNA targeting survivin sensitizes lung cancer cell with mutant p53 to adriamycin.2006
- Author(s)
  Yonesaka K, Tamura K, Kurata T, Satoh T, Ikeda M, Fukuoka M, Nakagawa K
- Journal Title
  
  Int J Cancer. 118
  
  Pages: 812-820
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Phase II Study of Etoposide and Cisplatin With Concurrent Twice-Daily Thoracic Radiotherapy Followed by Irinotecan and Cisplatin in Patients With Limited-Disease Small-Cell Lung Cancer :2006
- Author(s)
  Saito H, Takada Y, Ichinose Y, Eguchi K, Kudoh S, Matsui K, Nakagawa K, Takada M, Negoro S, Tamura K, ando M, Tada T, Fukuoka M.
- Journal Title
  
  J Clin Oncol. 24(33)
  
  Pages: 5247-52
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] A phase I/II study comparing regimen schedules of gemcitabine and docetaxel in Japanese patients with stage IIIB/IV non-small cell lung cancer.2005
- Author(s)
  Mtatsui K, Hirashima T, Nitta T, Kobayashi M, Ogata Y, Furukawa M, Kudoh S, Yoshimura N, Mukohara T, Yamauchi S, Shiraishi S, Kamoi H, Negoro S, Takeda K, Nakagawa K, Takada M, Yana T, Fukuoka M
- Journal Title
  
  Jpn J Clin Oncol. 35
  
  Pages: 181-187
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] A phase I/II study comparing regimen schedules of gemcitabine and docetaxel in Japanese patients with stage IIIB/IV non-small cell lung cancer2005
- Author(s)
  Matsui, K., Hirashima, T., Nitta, T., Kobayashi, M., Ogata, Y., Furukawa, M., Kudoh, S., Yoshimura, N., Mukohara, T., Yamauchi, S., Shiraishi, S., Kamoi, H., Negoro, S., Takeda, K., Nakagawa, K., Takada, M., Yana, T., Fukuoka, M.
- Journal Title
  
  Jpn J Clin Oncol 35
  
  Pages: 181-187
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Phase I-II study of amrubicin and cisplatin in previously untreated patients with extensive-stage small-cell lung cancer.2005
- Author(s)
  Ohe Y, Negoro S, Matsui K, Nakagawa K, Sugiura T, Takada Y, Nishiwaki Y, Yokota S, Kawahara M, Saijo N, Fukuoka M, Ariyoshi Y.
- Journal Title
  
  Ann Oncol. 16
  
  Pages: 430-436
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] A phase I/II study comparing regimen schedules of gemcitabine and docetaxel in Japanese patients with stage IIIB/IV non-small cell lung cancer.2005
- Author(s)
  Matsui K, Hirashima T, Nitta T, Kobayashi M, Ogata Y, Furukawa M, Kudoh S, Yoshimura N, Mukohara T, Yamauchi S, Shiraishi S, Kamoi H, Negoro S, Takeda K, Nakagawa K, Takada M, Yana T, Fukuoka M.
- Journal Title
  
  Jpn J Clin Oncol 35
  
  Pages: 181-187
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Phase I-II study of amrubicin and cisplatin in previously untreated patients with extensive-stage small-cell lung cancer.2005
- Author(s)
  Ohe Y, Negoro S, Matsui K, Nakagawa K, Sugiura T, Takada Y, Nishiwaki Y, Yokota S, Kawahara M, Saijo N, Fukuoka M, Ariyoshi Y
- Journal Title
  
  Ann Oncol. 16
  
  Pages: 430-436
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Phase I-II study of amrubicin and cisplatin in previously untreated patients with extensive-stage small-cell lung cancer2005
- Author(s)
  Ohe, Y., Negoro, S., Matsui, K., Nakagawa, K., Sugiura, T., Takada, Y., Nishiwaki, Y., Yokota, S., Kawahara, M., Saijo, N., Fukuoka, M., Ariyoshi, Y.
- Journal Title
  
  Ann Oncol 16
  
  Pages: 430-436
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Effect of re-treatment with gefitinib ('Iressa', ZD1839) after accuisition of resistance.2004
- Author(s)
  Kurata, T., Tamura, K., Kaneda, H., Nogami, T., Uejima, H., Asai, G., Nakagawa, K., Fukuoka, M.
- Journal Title
  
  Ann Oncol. 15
  
  Pages: 173-174
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Prediction of sensitivity of advanced non-small cell lung cancers to gefitinib (Iressa, ZD1839)2004
- Author(s)
  Kakiuchi, S., Daigo, Y., Ishikawa, N., Furukawa, C., Tsunoda, T., Yano, S., Nakagawa, K., Tsuruo, T., Kohno, N., Fukuoka, M., Sone, S., Nakamura, Y.
- Journal Title
  
  Hum Mol Genet 13
  
  Pages: 3029-3043
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Combination phase I study of nedaplatin and gemcitabine for advanced non-small-cell lung cancer2004
- Author(s)
  Kurata, T., Tamura, K., Yamamoto, N., Nogami, T., Satoh, T., Kaneda, H., Nakagawa, K., Fukuoka, M.
- Journal Title
  
  Br J Cancer. 90
  
  Pages: 2092-2096
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Randomized phase II study of docetaxel/ cisplatin versus docetaxel/ irinotecan in advanced non-small cell lung cancer : a West Japan Thoracic Oncology Study (WJT0G9803).2004
- Author(s)
  Yamamoto, N., Fukuoka, M., Negoro, S., Nakagawa, K., Saito, H., Matsui, K., Kawahara, M., Senba, H., Ta kada, Y., Kudoh, S., Nakano, T., Katakami, N., Sugiura, T., Hoso, T., Ariyoshi, Y.for the West Japan Thora cic Oncology Group.
- Journal Title
  
  Br J Cancer. 90
  
  Pages: 87-92
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Effect of re-treatment with gefitinib (' Iressa', ZD1839) after acquisition of resistance.2004
- Author(s)
  Kurata, T., Tamura, K., Kaneda, H., Nogami, T., Uejima, H., Asai, G., Nakagawa, K., Fukuoka, M.
- Journal Title
  
  Ann Oncol. 15
  
  Pages: 173-174
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Effect of re-treatment with gefitinib ('Iressa', ZD1839) after acquisition of resistance2004
- Author(s)
  Kurata, T., Tamura, K., Kaneda, H., Nogami, T., Uejima, H., Asai, G., Nakagawa, K., Fukuoka, M.
- Journal Title
  
  Ann Oncol 15
  
  Pages: 173-174
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Prediction of sensitivity of advanced non-small cell lung cancers to gefitinib (Iressa, ZD1839).2004
- Author(s)
  Kakiuchi, S., Daigo, Y., Ishikawa, N., Furukawa, C., Tsunoda, T., Yano, S., Nakagawa, K., Tsuruo, T., Kohno, N., Fukuoka, M., Sone, S., Nakamura, Y.
- Journal Title
  
  Hum Mol Genet. 13
  
  Pages: 3029-3043
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Randomized phase II study of docetaxel/ cisplatin versus docetaxel / irinotecan in advanced non-small cell lung cancer : a West Japan Thoracic Oncology Study (WJTOG9803).2004
- Author(s)
  Yamamoto, N., Fukuoka, M., Negoro, S., Nakagawa, K., Saito, H., Matsui, K., Kawahara, M., Senba, H., Takada, Y., Kudoh, S., Nakano, T., Katakami, N., Sugiura, T., Hoso, T., Ariyoshi, Y.
- Journal Title
  
  Br J Cancer. 90
  
  Pages: 87-92
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Randomized phase II study of docetaxel/ cisplatin versus docetaxel/ irinotecan in advanced non-small cell lung cancer : a West Japan Thoracic Oncology Study (WJTOG98O3)2004
- Author(s)
  Yamamoto, N., Fukuoka, M., Negoro, S., Nakagawa, K., Saito, H., Matsui, K., Kawahara, M., Senba, H., Takada, Y., Kudoh, S., Nakano, T., Katakami, N., Sugiura, T., Hoso, T., Ariyoshi, Y.for the West Japan Thoracic Oncology Group
- Journal Title
  
  Br J Cancer 90
  
  Pages: 87-92
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Combination phase I study of nedaplatin and gemcitabine for advanced non-small-cell lung cancer.2004
- Author(s)
  Kurata, T., Tamura, K., Yamamoto, N., Nogami, T., Satoh, T., Kaneda, H., Nakagawa, K., Fukuoka, M.
- Journal Title
  
  Br J Cancer. 90
  
  Pages: 2092-2096
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Retrospective analysis of the predictive factors associated with the response and survival benefit of gefitinib in patients with advanced non-small-cell lung cancer.2004
- Author(s)
  Kaneda, H., Tamura, K., Kurata, T., Uejima, H., Nakagawa, K., Fukuoka, M.
- Journal Title
  
  Lung Cancer. 46
  
  Pages: 247-254
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Retrospective analysis of the predictive factors associated with the response and survival benefit of gefitinib in patients with advanced non-small-cell lung cancer2004
- Author(s)
  Kaneda, H., Tamura, K., Kurata, T., Uejima, H., Nakagawa, K., Fukuoka, M.
- Journal Title
  
  Lung Cancer 46
  
  Pages: 247-254
- Data Source
  KAKENHI-PROJECT-16390238
[Journal Article] Combination phase I study of nedaplatin and gemcitabine for advanced non-small-cell lung cancer2004
- Author(s)
  Kurata, T., Tamura, K., Yamamoto, N., Nogami, T., Satoh, T., Kaneda, H., Nakagawa, K., Fukuoka, M.
- Journal Title
  
  Br J Cancer 90
  
  Pages: 2092-2096
- Data Source
  KAKENHI-PROJECT-16390238
[Presentation] heregulin発現HER2陽性乳癌・胃癌における抗HER2薬ラパチニブ、トラスツズマブ、T-DM1の感受性に関する研究2017
- Author(s)
  野長瀬祥兼, 米阪仁雄, 川上尚人, 渡邉諭美, 原谷浩司, 高濱隆幸, 武川直樹, 植田勲人, 谷崎潤子, 林秀敏, 吉田健史, 武田真幸, 千葉康敬, 田村孝雄, 中川和彦, 鶴谷純司
- Organizer
  第25回日本乳癌学会総会
- Data Source
  KAKENHI-PROJECT-26430174
[Presentation] T-DM1 de novo 耐性HER2陽性乳癌の臨床病理学的検討2017
- Author(s)
  酒井瞳, 岩朝勤, 菰池佳史, 鶴谷純司, 坂井和子, 西尾和人, 中川和彦
- Organizer
  第25回日本乳癌学会総会
- Data Source
  KAKENHI-PROJECT-26430174
[Presentation] Antitumor action of the MET tyrosine kinase inhibitor crizotinib in gastric cancer positive for MET amplification2013
- Author(s)
  Wataru Okamoto, Isamu Okamoto, Hisato Kawakami, Kazuyoshi Yanagihara, Kazuto Nishio, Kazuhiko Nakagawa
- Organizer
  International Symposium of Korean Society of Gastrointestinal Cancer
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-24501360
[Presentation] サバイビンを標的としたEGFR チロシンキナーゼ阻害剤に対する耐性克服2013
- Author(s)
  岡本勇,岡本邦男,清水俊雄,中川和彦
- Organizer
  第17回日本がん分子標的治療学会学術集会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2013-06-13
- Data Source
  KAKENHI-PROJECT-23501316
[Presentation] サバイビンを標的としたEGFRチロシンキナーゼ阻害剤に対する耐性克服2013
- Author(s)
  岡本勇、岡本邦男、清水俊雄、中川和彦
- Organizer
  第17回日本がん分子標的治療学会学術集会
- Place of Presentation
  京都市左京区
- Data Source
  KAKENHI-PROJECT-23501316
[Presentation] MET遺伝子増幅陽性胃癌に対するMETチロシンキナーゼ阻害剤クリゾチニブの抗腫瘍効果2012
- Author(s)
  岡本渉、岡本勇、荒尾徳三、仁科慎一、上田眞也、川上尚人、柳原五吉、倉田宝保、西尾和人、中川和彦
- Organizer
  第10回日本臨床腫瘍学会学術集会
- Place of Presentation
  大阪府大阪市大阪国際会議場
- Data Source
  KAKENHI-PROJECT-24501360
[Presentation] MassARRAYによるEML4-ALK検出系の構築2012
- Author(s)
  坂井和子、岡本勇、竹澤健、平島智徳、金田裕靖、武田真幸、松本和子、木村英晴、藤田至彦、中川和彦、荒尾徳三、西尾和人
- Organizer
  第10回日本臨床腫瘍学会学術集会
- Place of Presentation
  大阪府大阪市大阪国際会議場
- Data Source
  KAKENHI-PROJECT-24501359
[Presentation] Clinical outcome for EML4-ALK-positive patients with advanced non-small cell lung cancer treated with first-line platinumbased　chemotherapy.2012
- Author(s)
  Masayuki Takeda, Isamu Okamoto, Kazuko Sakai, Hisato Kawakami, Kazuto Nishio, Kazuhiko Nakagawa.
- Organizer
  第10回日本臨床腫瘍学会学術集会
- Place of Presentation
  大阪府大阪市大阪国際会議場
- Data Source
  KAKENHI-PROJECT-24501359
[Presentation] Multiplex genomic profiling of non-small cell lung cancer patients enrolled in the LETS phase III trial of first-line S-1/carboplatin versus paclitaxel/carboplatin (WJOG6611LTR)
- Author(s)
  H Yoshioka, I Okamoto, K Sakai, S Morita, H Kaneda, K Takeda, T Hirashima, Y Kogure, T Kimura, T Takahashi, S Atagi, T Seto, T Sawa, M Yamamoto, M Satouchi, M Okuno, S Nagase, K Nakagawa, Y Nakanishi, K Nishio
- Organizer
  ASCO Annual Meeting
- Place of Presentation
  Chicago
- Year and Date
  2014-05-30 – 2014-06-03
- Data Source
  KAKENHI-PROJECT-24501359

1. OKAMOTO Isamu (10411597)

# of Collaborated Projects: 5 results

# of Collaborated Products: 51 results
2. NISHIO Kazuto (10208134)

# of Collaborated Projects: 3 results

# of Collaborated Products: 26 results
3. FUKUOKA Masahiro (20047202)

# of Collaborated Projects: 2 results

# of Collaborated Products: 55 results
4. TAMURA Kenji (60340783)

# of Collaborated Projects: 2 results

# of Collaborated Products: 27 results
5. OKAMOTO Kunio (90460865)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
6. SAKAI Kazuko (20580559)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
7. OKAMOTO Wataru (30441075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. ARAO Tokuzo (20441074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. TSURUTANI Junji (30319686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
10. HIDA Toyoaki (80250249)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SATOH Taroh (40368303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 宮崎昌樹 (90319682)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 米阪仁雄 (30330260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
14. 倉田宝保 (40340781)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
15. 津谷あす香 (90351600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KAWAKAMI Hisato

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. 有吉寛

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 前西修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakagawa Kazuhiko 中川 和彦

NAKAGAWA Kazuhiko 中川 和彦

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[Journal Article] [fam‐] trastuzumab deruxtecan, antitumor activity is dependent on HER2 expression level rather than on HER2 amplification2019

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DOI

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[Journal Article] Targeting of the HER2/HER3 signaling axis overcomes ligand-mediated resistance to trastuzumab in HER2-positive breast cancer2019

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[Journal Article] Mutational activation of the epidermal growth factor receptor down-regulates major histocompatibility complex class I expression via the extracellular signal-regulated kinase in non-small cell lung cancer2018

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[Journal Article] HER2 genomic amplification in circulating tumor DNA and estrogen receptor positivity predict primary resistance to trastuzumab emtansine (T-DM1) in patients with HER2-positive metastatic breast cancer.2018

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[Journal Article] DS-8201a, a new HER2-targeting antibody-drug conjugate incorporating a novel DNA topoisomerase I inhibitor, overcomes HER2-positive gastric cancer T-DM1 resistance2017

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[Journal Article] HER2 genomic amplification in circulating tumor DNA from patients with cetuximab-resistant colorectal cancer2016

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[Journal Article] Heregulin-expressing HER2-positive breast and gastric cancer exhibited heterogeneous susceptibility to the anti-HER2 agents lapatinib, trastuzumab and T-DM1.2016

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[Journal Article] Survival outcome assessed according to tumor response and shrinkage pattern in patients with EGFR mutation-positive non-small cell lung cancer treated with gefitinib or erlotinib.2014

Nakagawa Kazuhiko 中川和彦

NAKAGAWA Kazuhiko 中川和彦