SEGAWA Tomoya 瀬川智也

Researcher Number	40301197
External Links
Affiliation (based on the past Project Information) *help	2003: 金沢大, 医学部附属病院, 助手 2002: University Hospital, 医学部附属病院, Assistant Professor 1998 – 2001: 金沢大学, 医学部・附属病院, 助手
Review Section/Research Field	Principal Investigator Obstetrics and gynecology Except Principal Investigator Obstetrics and gynecology / Biological Sciences
Keywords	Principal Investigator アロマターゼ / 子宮体癌 Except Principal Investigator エストロゲン / アロマターゼ / Estrogen / 子宮内膜症 / Chemokine / CINC / サイトカイン / ストレス … More / ケモカイン / 生殖生理 / Aromatase / 子宮筋腫 / PCR / Gonadal function / Cytokine / Stress / Reproductive physiology / 性機能 / ovulation / estrogen / IL-β / steroidogenic factor-1 / granulosa cells / aromatase / IL=1β / 排卵障害 / IL-1β / SF-1 / 顆粒膜細胞 / Clinical trial / GnRH agonist / Aromatase inhibitor / Leromyoma of the uterus / Endometriosis / GnRH アゴニスト / アロマターゼインヒビター / アロマターゼ阻害例 / 臨床治験 / GnRHアゴニスト / アロマターゼ阻害剤 / Hypothalamus / Rat / Human / Hypoglycemia / Gro-α / stress / 運動 / 分娩 / ケモンカイン / 低血糖 / 視床下部 / GRO-α / Molecular biology / autocrine mechanism / In situ estrogen / Leiomyoma of the uterus / 転写制御 / プロモーター / 分子生物学 / オートクライン機構 / anti HPV antibody / HLA class II antigen / Immunoresponse / cervical cancer / Human papillomavirus / HPV DNA診断 / 免疫 / 癌抑制遺伝子 / HLAclassII抗原 / ウイルス様粒子(VLP) / 抗HPV抗体 / HLA classII抗原 / 宿主免疫応答 / 子宮頚癌 / HPV / 乳癌 / 遺伝子多型 Less

エストロゲン合成酵素の遺伝子多型が酵素活性および乳癌の発生率に及ぼす影響
- Principal Investigator
  
  SHOZU Makio
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
子宮体癌に対するアロマターゼ遺伝子をターゲットとした遺伝子治療への戦略Principal Investigator
- Principal Investigator
  
  瀬川智也
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kanazawa University
Mechanism of stress-induced derangement of gonadal function in the neuro-endocrine-immune networks
- Principal Investigator
  
  KOIKE Koji
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kanazawa University
Steroidogenic factor-1 as a therapeutic target for of severe ovarian failure
- Principal Investigator
  
  SHOZU Makio
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kanazawa University
THERAPUETIC APPLICATION OF AROMATASE INHIBITOR FOR LEIOMYOMA OF THE UTERUS AND ENDOMETRIOSIS
- Principal Investigator
  
  AHOZU Makio
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KANAAWA UNIVERSITY
Studies on over-expression of aromatase in leiomyoma of the uterus and its application for conservative management
- Principal Investigator
  
  SHOZU Makio
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kanazawa University
Research on role of chemokine in reproductive physiology
- Principal Investigator
  
  KOIKE Koji
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  kanazawa University
Study of immunologic evasion of human papllomavirus (HPV) Against host immuno-ersponse in patient with cervical cancer
- Principal Investigator
  
  SASAGAWA Toshiyuki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kanazawa University

All 2004 2003 2002 2001 2000 Other

All Journal Article

[Journal Article] Sex-determining region Y levels in maternal plasma : Evaluation in abnormal pregnancy.2004
- Author(s)
  Shimada K, Murakami K, Shozu M, Segawa T, Sumitani H, Inoue M
- Journal Title
  
  J Obstet Gynaecol Res. 30・2
  
  Pages: 148-54
- NAID
  10013778898
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470348
[Journal Article] Sex-determining region Y levels in maternal plasma : Evaluation in abnormal pregnancy.2003
- Author(s)
  Shimada K, Murakami K, Shozu M, Segawa T, Sumitani H, Inoue M.
- Journal Title
  
  J Obstet Gynaecol Res 30・2
  
  Pages: 148-154
- NAID
  10013778898
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470348
[Journal Article] Successful Treatment of Symptomatic Uterine Leiomyoma with a Non-steroidal Aromatase Inhibitor in a Perimenopausal Woman2003
- Author(s)
  Shozu M, Murakami K, Segawa T, Kasai T, Inoue M
- Journal Title
  
  Fertil Steril. 79・3
  
  Pages: 628-631
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470348
[Journal Article] Temporary amniotic membrane patching for acute chemical burns.2003
- Author(s)
  Kobayashi A, Shirao Y, Yoshita T, Yagami K, Segawa Y, Kawasaki K, Shozu M, Tseng SC.
- Journal Title
  
  Eye. 17・2
  
  Pages: 149-158
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470348
[Journal Article] Temporary amniotic membrane patching for acute chemical bums.2003
- Author(s)
  Kobayashi, A., Shirao, Y., Yoshita, T., Yagami, K., Segawa, Y., Kawasaki, K., Shozu, M., Tseng, S.C.
- Journal Title
  
  Eye 17
  
  Pages: 149-158
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12557136
[Journal Article] Successful Treatment of Symptomatic Uterine Leiomyoma with a Non-Steroidal Aromatase Inhibitor in a Perimenopausal Woman2003
- Author(s)
  Shozu, M., Murakami, K., Segawa, T., Kasai, T., Inoue, M.
- Journal Title
  
  Fertil Steril 79
  
  Pages: 628-631
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12557136
[Journal Article] Temporaty amniotic memebrane patching for acute chemical burns.2003
- Author(s)
  Kobayashi A., Shirao, Y., Yoshia T,, Yagami K., Segawa Y., Kawasaki K., Shozu M., Tseng SC.
- Journal Title
  
  Eye 17
  
  Pages: 149-158
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12557136
[Journal Article] Successful treatment of a symptomatic uterine leiomyoma in a perimenopausal woman with a nonsteroidal aromatase inhibitor.2003
- Author(s)
  Shozu M, Murakami K, Segawa T, Kasai T, Inoue M.
- Journal Title
  
  Fertil Steril. 79(3)
  
  Pages: 628-931
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12557136
[Journal Article] Successful Treatment of Symptomatic Uterine Leiomyoma with a Non-Steroidal Aromatase Inhibitor in a Perimenopausal Woman2003
- Author(s)
  Shozu M, Murakami K, Segawa T, Kasai T, Inoue M.
- Journal Title
  
  Fertil Steril. 79・3
  
  Pages: 628-31
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470348
[Journal Article] Temporary amniotic membrane patching for acute chemical burns.2003
- Author(s)
  Kobayashi A, Shirao Y, Yoshita T, Yagami K, Segawa Y, Kawasaki K, Shozu M, Tseng SC
- Journal Title
  
  Eye. 17・2
  
  Pages: 149-58
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470348
[Journal Article] Fetal DNA levels in maternal blood correlated with fetal prognosis in a case of intervillous hematoma.2003
- Author(s)
  Murakami K, Shimada K, Maeda E, Segawa T, Shozu M, Inoue M
- Journal Title
  
  Am JPerinatol 20・7
  
  Pages: 361-6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470348
[Journal Article] Fetal DNA levels in maternal blood correlated with fetal prognosis in a case of intervillous hematoma.2003
- Author(s)
  Murakami K, Shimada K, Maeda E, Segawa T, Shozu M, Inoue M.
- Journal Title
  
  Am J Perinatol. 20・7
  
  Pages: 361-366
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470348
[Journal Article] Spatially Heterogenous Expression of Aromatase P450 through Promoter II Is Closely Correlated with the Level of Steroidogenic Factor-1 Transcript in Endometrioma Tissues.2002
- Author(s)
  Yang HJ, Shozu M, Murakami K, Sumitani H, Segawa T, Kasai T, Inoue M
- Journal Title
  
  J Clin Endocrinol Metab. 87(8)
  
  Pages: 3745-53
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12557136
[Journal Article] Spatially heterogeneous expression of aromatase P450 through promoter II is closely correlated with the level of steroidogenic factor-1 transcript in endometrioma tissues.2002
- Author(s)
  Yang, H.J., Shozu, M., Murakami, K., Sumitani, H., Segawa, T., Kasai, T., Inoue, M.
- Journal Title
  
  J Clin Endocrinol Metab 87
  
  Pages: 3745-3753
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12557136
[Journal Article] Over-expression of aromatase P-450 in leiomyoma tissues is driven through the promoter 1.4 of aromatase P-450.2002
- Author(s)
  Shozu, M., Sumitani, H., Segawa, T., Yang, H.-J., Murakami, K., Kasai, T., Inoue, M.
- Journal Title
  
  J Clin Endocrinol Metab 87
  
  Pages: 2540-2548
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12557136
[Journal Article] Leak-proof puncture of ovarian cysts : instant mounting of plastic bag using cyanoacrylate adhesive.2002
- Author(s)
  Shozu, M., Segawa, T., Sumitani, H., Inoue, M
- Journal Title
  
  Obstet Gynecol 97
  
  Pages: 1007-1010
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12557136
[Journal Article] Spatially Heterogenous Expression of Aromatase P450 through Promoter II Is Closely Correlated with the Level of Steroidogenic Factor-1 Transcript in Endometrioma Tissues.2002
- Author(s)
  Yang HJ, Shozu M, Murakami K, Sumitani H, Segawa T, Kasai T, Inoue M.^*
- Journal Title
  
  J Clin Endocrinol Metab. 87(8)
  
  Pages: 3745-53
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470348
[Journal Article] Over-expression of aromatase P-450 in leiomyoma tissues is driven through the promoter 1.4 of aromatase P-450.2002
- Author(s)
  Shozu, M., Sumitani, H., Segawa, T., Yang, H.-J., Murakami, K., Kasai, T., Inoue, M.
- Journal Title
  
  J Clin Endocrinol Metab 87
  
  Pages: 2540-2548
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470348
[Journal Article] Over-expression of aromatase P450 in leiomyoma tissues is driven through the promoter 1.4 of aromatase P-450.2002
- Author(s)
  Shozu, M., Sumitani, H., Segawa, T., Yang, H.-J., Murakami, K., Kasai, T., Inoue, M.
- Journal Title
  
  J Clin Endocrinol Metab 87
  
  Pages: 2540-2548
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12557136
[Journal Article] Over-expression of aromatase P-450 in leiomyoma tissues in driven through the promoter I.4 of aromatase P-450.2002
- Author(s)
  Shozu, M., Sumitani, H., Segawa, T., Yang, H.-J., Murakami, K., Kasai, T., Inoue, M.
- Journal Title
  
  J Clin Endocrinol Metab 87
  
  Pages: 2540-2548
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470348
[Journal Article] Spatially Heterogenous Expression of Aromatase P450 through Promoter II Is Closely Correlated with the Level of Steroidogenic Factor-1 Transcript in Endometrioma Tissues.2002
- Author(s)
  Yang HJ, Shozu M, Murakami K, Sumitani H, Segawa T, Kasai T, Inoue M
- Journal Title
  
  J Clin Endocrinol Metab. 87(8)
  
  Pages: 3745-3753
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470348
[Journal Article] Regulation of aromatase activity in bone-derived cells : possible role of mitogen-activated protein kinase2001
- Author(s)
  Shozu M, Sumitani H, Murakami K, Segawa T, Hei-Juan Yang, Inoue M.
- Journal Title
  
  Steroid Biochem Mol Biol 79(1-5)
  
  Pages: 61-65
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470348
[Journal Article] Inhibition of in situ expression of aromatase P450 in leiomyoma of the uterus by leuprorelin acetate.2001
- Author(s)
  Shozu M, Sumitani H, Segawa S, Yang HJ, Murakami K, Inoue M.
- Journal Title
  
  J Clin Endocrinol Metab. 86(11)
  
  Pages: 5405-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12557136
[Journal Article] Regulation of aromatase activity in bone-derived cells : nossible2001
- Author(s)
  Shozu, M., Sumitani, H., Murakami, K., Segawa, T., Yang, H.J., Inoue, M.
- Journal Title
  
  J Steroid Biochem Mol Biol 79
  
  Pages: 61-65
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12557136
[Journal Article] Inhibition of in situ expression of aromatase P450 in leiomyoma of the uterus by leuprorelin acetate.2001
- Author(s)
  Shozu M, Sumitani H, Segawa S, Yang HJ, Murakami K, Inoue M.
- Journal Title
  
  J Clin Endocrinol Metab. 86(11)
  
  Pages: 5405-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470348
[Journal Article] Leak-proof puncture of ovarian cysts : instant mounting of plastic bag using cyanoacrylate adhesive.2001
- Author(s)
  Shozu, M., Segawa, T., Sumitani, H., Inoue, M.
- Journal Title
  
  Obstet Gynecol 97
  
  Pages: 1007-1010
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12557136
[Journal Article] Inhibition of in situ expression of aromatase P450 in leiomyoma of the uterus by leunrorelin acetate.2001
- Author(s)
  Shozu M, Sumitani H, Segawa S, Yang HJ, Murakami K, Inoue M.
- Journal Title
  
  J Clin Endocrinol Metab. 86(11)
  
  Pages: 5405-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12557136
[Journal Article] Inhibition of in situ expression of aromatase P450 in leiomyoma of the uterus by leuprorelin acetate.2001
- Author(s)
  Shozu M, Sumitani H, Segawa S, Yang HJ, Murakami K, Inoue M
- Journal Title
  
  J Clin Endocrinol Metab. 86(11)
  
  Pages: 5405-5411
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470348
[Journal Article] Regulation of aromatase activity in bone-derived cells : possible role of mitogen-activated protein kinase2001
- Author(s)
  Shozu M, Sumitani H, Murakami K, Segawa T, Hei-Juan Yang, Inoue M.
- Journal Title
  
  Steroid Biochem Mol Biol. 79(1-5)
  
  Pages: 61-65
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470348
[Journal Article] Leak-proof puncture of ovarian cysts : instant mounting of plastic bag using cyanoacrylate adhesive.2001
- Author(s)
  Shozu, T.Segawa, H.Sumitani, M.Inoue
- Journal Title
  
  Obstet Gynecol 97(6)
  
  Pages: 1007-1010
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470348
[Journal Article] Regulation of aromatase activity in bone-derived cells : possible role of mitogen-activated protein kinase.2001
- Author(s)
  Shozu, M., Sumitani, H., Murakami, K., Segawa, T., Yang, H.J., Inoue, M.
- Journal Title
  
  J Steroid Biochem Mol Biol 79
  
  Pages: 61-65
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12557136
[Journal Article] In situ estrogen synthesized by aromatase P450 in uterine leiomyoma cells promotes cell growth probably via an autocrine/intracrine mechanism.2000
- Author(s)
  Sumitani H, Shozu M, Segawa T, Murakami K, Yang HJ, Shimada K, Inoue M.
- Journal Title
  
  Endocrinology 141(10)
  
  Pages: 3852-3861
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12557136
[Journal Article] Decreased expression of early growth response-1 and its role in uterine leiomyoma growth.
- Author(s)
  Shozu M, Murakami K, Segawa T, Kasai T, Ishikawa H, Shinohara K, Okada M, Inoue M
- Journal Title
  
  Cancer Res. (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470348
[Journal Article] Decreased expression of early growth response-1 and its role in uterine leiomyom a growth
- Author(s)
  Shozu M, Murakami K, Segawa T, Kasai T, Ishikawa H, Shinohara K, Okada M, Inoue M
- Journal Title
  
  Cancer Res. In press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470348

1. SHOZU Makio (30226302)

# of Collaborated Projects: 5 results

# of Collaborated Products: 34 results
2. MURAKAMI Kouichi (20242555)

# of Collaborated Projects: 5 results

# of Collaborated Products: 27 results
3. KOIKE Koji (70225340)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. INOUE Masaki (10127186)

# of Collaborated Projects: 5 results

# of Collaborated Products: 30 results
5. SASAGAWA Toshiyuki (30272975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YAMASHIMA Tetsumori (60135077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SUZUKI Nobutaka (60251930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 津川浩一郎 (60313657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SEGAWA Tomoya 瀬川 智也

Research Projects

Research Products

Co-Researchers

エストロゲン合成酵素の遺伝子多型が酵素活性および乳癌の発生率に及ぼす影響

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

子宮体癌に対するアロマターゼ遺伝子をターゲットとした遺伝子治療への戦略Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of stress-induced derangement of gonadal function in the neuro-endocrine-immune networks

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Steroidogenic factor-1 as a therapeutic target for of severe ovarian failure

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

THERAPUETIC APPLICATION OF AROMATASE INHIBITOR FOR LEIOMYOMA OF THE UTERUS AND ENDOMETRIOSIS

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on over-expression of aromatase in leiomyoma of the uterus and its application for conservative management

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on role of chemokine in reproductive physiology

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of immunologic evasion of human papllomavirus (HPV) Against host immuno-ersponse in patient with cervical cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Sex-determining region Y levels in maternal plasma : Evaluation in abnormal pregnancy.2004

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Sex-determining region Y levels in maternal plasma : Evaluation in abnormal pregnancy.2003

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Successful Treatment of Symptomatic Uterine Leiomyoma with a Non-steroidal Aromatase Inhibitor in a Perimenopausal Woman2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] Temporary amniotic membrane patching for acute chemical burns.2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] Temporary amniotic membrane patching for acute chemical bums.2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] Successful Treatment of Symptomatic Uterine Leiomyoma with a Non-Steroidal Aromatase Inhibitor in a Perimenopausal Woman2003

SEGAWA Tomoya 瀬川智也