Shimada Masaru 島田勝

… Alternative Names

SHIMADA Masaru 島田勝

XIN Ke Qin 忻克勤

忻克〓キンカッキン

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Researcher Number	40301452
Other IDs
Affiliation (Current)	2025: 横浜市立大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2014 – 2023: 横浜市立大学, 医学部, 准教授 2010: 横浜市立大学, 大学院・医学研究科, 准教授 2007 – 2010: Yokohama City University, 医学研究科, 准教授 2008: Yokohama City University, 医学部, 准教授 2005 – 2006: 横浜市立大学, 医学部, 準教授 … More 2004: 横浜市立大学, 医学部, 講師 1999 – 2003: 横浜市立大学, 医学部, 助手 1998: 自治医科大学, 衛生学, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology / Virology / Hygiene Except Principal Investigator Bacteriology (including Mycology) / Bacteriology (including Mycology) / Orthopaedic surgery / Infectious disease medicine
Keywords	Principal Investigator HPV / virus-cell interaction / CRISPR/Cas9 / アポトーシス / cell factor / 細胞必須因子 / 感染 / 子宮頸癌 / 細胞受容体 / virus binding protein … More / 受容体 / 質量分析法 / 免疫沈降法 / アポト－シス / 発癌遺伝子 / apoptosis / E6 / 感染細胞 / アデノ随伴ウイルス(AAV) / HIV / AAV / DNA fragmentation / Apoptosis / Necrosis / 腎障害 / 肝障害 / カドミウム … More Except Principal Investigator DNAワクチン / HIV / DNA vaccine / 緑膿菌 / TGF-β / LacZ / CTL / influenza virus / ウイルスベクター / HIV-1 / 鞭毛抗原 / インフルエンザウイルス / 新世代DNAワクチン / clinical investigation / type III secretion mechanism protein / flagella antigen / triple vaccine / Pseudomonas aeruginosa / natural immunity (TLR5 etc..) / TLR5 / 自然免疫 / 多価ワクチン / 臨床試験 / III型分泌機構蛋白質 / 三者混合ワクチン / 自然免疫(TLR5など) / 35 virus / adeno 5 / El deficient adeno virus / pseudomonas / Virus vector / F35ウイルス / アデノ5 / E1欠損型アデノウイルス / AAV vector / cartilage repair / periosteal cell / アデノ随伴ウイルスベクター / TGF-B / アデノ髄伴ウイルスベクター / 軟骨修復 / 骨膜細胞 / activated T cell / adjuvant effect / CpG motif / 組換ウイルスベクター / HIV-1 DNAワクチン / 経直腸 / 経膣 / 経皮 / 組み換えアデノウイルス / 活性化Tリンパ球 / 活性化T細胞 / アジュバント効果 / CpGモチーフ / cytotoxic T lymphocyte / epitope / cytokine expression plasmid / vaccine for the next generation / Pseudomonas / humanized codon / 細胞障害性T細胞(CTLs) / 粘膜免疫反応 / アデノ随伴ウイルス / サイトカインアジュバント / 感染防御抗原 / ヒト化コドン / エクソトキシンA / 抗原決定基 / CTLエピトープ / エラスターゼ / インフルエンザ / 緑膿菌ワクチン / 細胞障害製T細胞(CTL) / サイトカイン発現プラスミド / エピトープ / ヒト型コドン / ビフィズス菌 / 粘膜免疫 / 腸チフス / ワクチン Less

ゲノム編集技術を使用したヒトパピローマウイルスの感染機構に関する研究Principal Investigator
- Principal Investigator
  
  島田勝
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Yokohama City University
Elucidation of the cell infection mechanism of human papilloma virus using genome editing techniquePrincipal Investigator
- Principal Investigator
  
  SHIMADA Masaru
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Yokohama City University
A study for human papillomavirus (HPV) infection mechanismPrincipal Investigator
- Principal Investigator
  
  Shimada Masaru
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yokohama City University
A global study for HPV-cell infection mechanismPrincipal Investigator
- Principal Investigator
  
  SHIMADA Masaru
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yokohama City University
Novel oral vaccine using genetically engineering bifidobacterium displaying antigen on its cell-surface
- Principal Investigator
  
  SHIRAKAWA Toshiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Kobe University
Adeno-associate virus (AAV) induces apoptosis of HIV-infected cellsPrincipal Investigator
- Principal Investigator
  
  SHIMADA Masaru
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Yokohama City University
Novel Vaccines against Pseudomonas aeruginosa and Other Microorganisms
- Principal Investigator
  
  OKUDA Kenji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Yokohama city university
Developmental research of new generation DNA vaccine against microorganism using synthesized DNA
- Principal Investigator
  
  OKUDA Kenji
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  YOKOHAMA CITY UNIVERSITY
The adjuvant effects of CpG motif and activated large number of activated-T lymphocytes on immunoresponses.
- Principal Investigator
  
  HAMAJIMA Kenji
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Yokohama City University
Gene transfer to periosteum-derived cells for cartilage repair
- Principal Investigator
  
  KAWAI Kosei, 河合孝誠
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Department of Orthpaedic Surgery, Yokohama city university
Enhancement of protection against various microbial infection by the modification of dominance of Thl or Th2 immune responses
- Principal Investigator
  
  OKUDA Kenji
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Yokohama City University
肝のアポトーシスか、ネクローシスか:カドミウム腎障害発症機序の解明Principal Investigator
- Principal Investigator
  
  忻克勤 (忻克〓)
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hygiene
- Research Institution
  Yokohama City University
  Jichi Medical University

[Journal Article] Biodistribution and immunity of adenovirus 5/35 and modified vaccinia Ankara vector vaccines against human immunodeficiency virus 1 clade C2022
- Author(s)
  Shimada Masaru、Wang Haibin、Ichino Motohide、Ura Takehiro、Mizuki Nobuhisa、Okuda Kenji
- Journal Title
  
  Gene Therapy
  
  Volume: 29 Issue: 10-11 Pages: 636-642
- DOI
  10.1038/s41434-021-00308-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09603
[Journal Article] Current Vaccine Platforms in Enhancing T-Cell Response2022
- Author(s)
  Ura Takehiro、Takeuchi Masaki、Kawagoe Tatsukata、Mizuki Nobuhisa、Okuda Kenji、Shimada Masaru
- Journal Title
  
  Vaccines
  
  Volume: 10 Issue: 8 Pages: 1367-1367
- DOI
  10.3390/vaccines10081367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09603
[Journal Article] Prophylactic and therapeutic vaccine against Pseudomonas aeruginosa keratitis using bacterial membrane vesicles2021
- Author(s)
  Ito S, Nakamura J, Fukuta M, Ura T, Teshigawara T, Fukushima J, Mizuki N, Okuda K, Shimada M.
- Journal Title
  
  Vaccine
  
  Volume: 39 Issue: 23 Pages: 3152-3160
- DOI
  10.1016/j.vaccine.2021.04.035
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09603
[Journal Article] Vaccination inhibits the human adenoviral transduction in a mouse keratoconjunctivits model.2021
- Author(s)
  Fukuda M, Nakamura J, Ito S, Kawazoe K, Miyanaga Y, Teshigawara T, Okuda K, Mizuki N, Shimada M.
- Journal Title
  
  Vaccine
  
  Volume: 39 Issue: 26 Pages: 3498-3508
- DOI
  10.1016/j.vaccine.2021.05.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09603
[Journal Article] Therapeutic antibody for epidemic keratoconjuctivitis in a rabbit model.2021
- Author(s)
  Shimada M, Mizuki N, Okuda K.
- Journal Title
  
  SL Vaccines And Vaccination J,
  
  Volume: 4 Pages: 122-123
- Data Source
  KAKENHI-PROJECT-20K09603
[Journal Article] アデノウイルスベクターを用いた角結膜感染モデルマウス作製の試み2021
- Author(s)
  福田理子, 島田勝, 伊藤沙織, 宮永嘉隆, 川添賢志, 河越龍方, 奥田研爾, 水木信久
- Journal Title
  
  あたらしい眼科
  
  Volume: 38 Pages: 337-341
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09603
[Journal Article] New vaccine production platforms used in developing SARS-CoV-2 vaccine candidates2021
- Author(s)
  Ura Takehiro、Yamashita Akio、Mizuki Nobuhisa、Okuda Kenji、Shimada Masaru
- Journal Title
  
  Vaccine
  
  Volume: 39 Issue: 2 Pages: 197-201
- DOI
  10.1016/j.vaccine.2020.11.054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09603, KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-20H03438
[Journal Article] The human papillomavirus E6 protein targets apoptosis-inducing factor (AIF) for degradation2020
- Author(s)
  Shimada M, Yamashita A, Saito M, Ichino M, Kinjo T, Mizuki N, Klinman DM, Okuda K
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1-14
- DOI
  10.1038/s41598-020-71134-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08655, KAKENHI-PROJECT-20K09603, KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-20H03438
[Journal Article] Basic FGF or VEGF gene therapy corrects insufficiency in the intrinsic healing capacity of tendons.2016
- Author(s)
  1.Tang JB, Wu YF, Cao Y, Chen CH, Zhou YL, Avanessian B, Shimada M, Wang XT, Liu PY.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 20643-20643
- DOI
  10.1038/srep20643
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462531
[Journal Article] Apoptosis of antigen-specific CTLs contributes to low immune response in gut-associated lymphoid tissue post vaccination.2014
- Author(s)
  Shimada M, Yoshizaki S, Ichino M, Klinman DM, Okuda K
- Journal Title
  
  Vaccine
  
  Volume: 32（40） Issue: 40 Pages: 5198-5205
- DOI
  10.1016/j.vaccine.2014.07.046
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462531
[Journal Article] Developments in viral vector-based vaccines.2014
- Author(s)
  Ura T, Okuda K, Shimada M
- Journal Title
  
  Vaccines
  
  Volume: 2（3） Issue: 3 Pages: 624-641
- DOI
  10.3390/vaccines2030624
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462531
[Journal Article] Recent developments in DNA vaccination.2014
- Author(s)
  Okuda, K., Wada, Y., Shimada, M
- Journal Title
  
  Vaccines
  
  Volume: 2（1） Issue: 1 Pages: 89-106
- DOI
  10.3390/vaccines2010089
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462531
[Journal Article] Designed Recombinant Adenovirus Type 5 Vector Induced Env-specific CD8+ Cytotoxic T lymphocytes and Cross-reactive Neutralizing Antibodies against Human Immunodeficiency Virus Type 12009
- Author(s)
  Ura, T., Yoshida, A., K-Q, Xin., Yoshizaki, S., Yashima, S., Abe, S., Mizuguchi, H., Okuda,K.
- Journal Title
  
  J. Gene Med 11巻
  
  Pages: 139-149
- Data Source
  KAKENHI-PROJECT-19590481
[Journal Article] Designed Recombinant Adenovirus Type 5 Vector Induced Env-specific CD8+ Cytotoxic T lymphocytes and Cross-reactive Neutralizing Antibodies against Human Immunodeficiency Virus Type1.2009
- Author(s)
  Ura, T., Yoshida, A., K-Q, Xin., Yoshizaki, S., Yashima, S., Abe, S., Mizuguchi, H., Okuda, K.
- Journal Title
  
  J. Gene Med 11
  
  Pages: 139-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590481
[Journal Article] Effect of therapeutic immunization using Ad5/35 and MVA vectors on SIV-infection of rhesus monkeys undergoing anti-retroviral therapy2009
- Author(s)
  Shimada, M., Wang, H-B., Kondo, A., Xu, X-P., Yoshida, A., Ura, T., Mizuguchi ,H., Klinman, D., Luo, J-L., Bai, H., Okuda, K.
- Journal Title
  
  Gene Ther 16巻
  
  Pages: 218-228
- Data Source
  KAKENHI-PROJECT-19590481
[Journal Article] Effect of therapeutic immunization using Ad5/35 and MVA vectors on SIV-infection of rhesus monkeys undergoing anti-retroviral therapy.2009
- Author(s)
  Shimada. M., Wang, H-B., Kondo, A., Xu, X-P., Yoshida, A., Ura, T., Mizuguchi, H., Klinman, D., Luo, J-L., Bai, H., Okuda, K.
- Journal Title
  
  Gene Ther. 16
  
  Pages: 218-228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590481
[Journal Article] Adenovirus type 5 with modified hexons induces robust transgene-specific immune responses in mice with pre-existing immunity against adenovirus type 52009
- Author(s)
  Abe, S., Okuda, K., Ura, T., Kondo, A., Yoshida, A., Yoshizaki, S., Mizuguchi, H., Klinman, D., Shimada, M.
- Journal Title
  
  J. Gene Med. 11巻
  
  Pages: 570-579
- Data Source
  KAKENHI-PROJECT-19590481
[Journal Article] Chimeric adenovirus 5/35 vector containing the clade C HIV gag gene induces a cross-reactive immune response against HIV2007
- Author(s)
  Xin, K-Q(Shimada, ら)
- Journal Title
  
  Vaccine 367
  
  Pages: 3809-3815
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590481
[Journal Article] The degree of apoptosis as an immunostimulant for a DNA vaccine against HIV-1 infection2007
- Author(s)
  Kojima, Y., Jounai, N., Takeshita, F., Nakazawa, M., Okuda, K., Watabe, S., Shimada, M., Okuda, K.
- Journal Title
  
  Vaccine 25巻
  
  Pages: 438-45
- Data Source
  KAKENHI-PROJECT-19590481
[Journal Article] The Atg5 Atg12 conjugate associates with innate antiviral immune responses2007
- Author(s)
  Jounai, N., Takeshita, F., Kobiyama, K., Sawano, A., Miyawaki, A., Shimada, M., Ishii, KJ, Kawai, T., Akira, S., Suzuki, K., Okuda, K.
- Journal Title
  
  PNAS 104巻
  
  Pages: 4050-4055
- Data Source
  KAKENHI-PROJECT-19590481
[Journal Article] Adeno-Associated Virus-2 Effectively Transduces Intrasynovial Tenocytes with Persistent Expression of the Transgene, but Other Serotypes do not2007
- Author(s)
  Wang, X-T, Xin, K-Q(Shimada, ら)
- Journal Title
  
  Plastic & Reconstructive Surgery 119
  
  Pages: 227-234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590481
[Journal Article] Blocking of the TLR5 activation domain hampers protective potential of flagellin DNA vaccine2007
- Author(s)
  Saha, S, Xin, K-Q(Shimada, ら)
- Journal Title
  
  Journal of Immunology 15
  
  Pages: 1147-1154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590481
[Journal Article] Blocking of the TLR5 activation domain hampers protective potential of flagellin DNA vaccine2007
- Author(s)
  Saha, S., Takeshita, F., Matsuda, T., Jounai, N., Kobiyama, K., Matsumoto, T., Sasaki, S., Yoshita, A., Shimada, M.., Klinmana, D.M., Uematsu, S., Ishii, KJ, Akira, S., Okuda, K.
- Journal Title
  
  J. Immunol 179巻
  
  Pages: 1147-1154
- Data Source
  KAKENHI-PROJECT-19590481
[Journal Article] Chimeric adenovirus type 5/35 vector encoding SIV gag and HIV env genes affords protective immunity against the simian/human immunodeficiency virus in monkeys.2007
- Author(s)
  Someya, K., Shimada, M.., Ami, Y., Izumi, Y., Mizuguchi, H., Ohta, S., Yamamoto, N., Honda, M., Okuda, K.
- Journal Title
  
  Virology 367巻
  
  Pages: 390-397
- Data Source
  KAKENHI-PROJECT-19590481
[Journal Article] Isolation and identification of adenovirus from conjunctival scrapings over a two-year period (between 2001 and 2003) in Yokohama, Japan2007
- Author(s)
  Matsui, K., Saha, S., saitoh, M., Mizuki, N., Itoh, N., Okada, E., Yashida, A., Shimada, M., Nishio, O., Okuda, K.
- Journal Title
  
  J. Med. Virol 79巻
  
  Pages: 200-205
- Data Source
  KAKENHI-PROJECT-19590481
[Journal Article] Chimeric adenovirus 5/35 vector containing the clade C HIV gag gene induces a cross-reactive immune response against HIV2007
- Author(s)
  Shimada, M., Sekimoto, Y., Takahashi, T., Mizuguchi, H., Ichino, M., Yoshida, A. Okuda, K.
- Journal Title
  
  Vaccine 25巻
  
  Pages: 3809-3815
- Data Source
  KAKENHI-PROJECT-19590481
[Journal Article] Induction of robust immune responses against human immunodeficiency virus is supported by the inherent tropism of adeno-associated virus type 5 for dendritic cells.2006
- Author(s)
  Xin KQ et al.
- Journal Title
  
  J Virol 80・24
  
  Pages: 11899-11910
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390129
[Journal Article] Induction of robust immune responses against human immunodeficiency virus is supported by the inherent tropism of adeno-associated virus type 5 for dendritic cells.2006
- Author(s)
  Xin KQ et al.
- Journal Title
  
  J Virol 80, 24
  
  Pages: 11899-11910
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390129
[Journal Article] Prime-boost vaccination with plasmid DNA and a chimeric adenovirus type 5 vector with type 35 fiber induces persistent protective immunity against HIV.2005
- Author(s)
  Xin K-Q et al.
- Journal Title
  
  Gen. Ther 12・24
  
  Pages: 1769-1777
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390129
[Journal Article] Comparison of antigen-specific cellurar immune responses between individual PBMCs and splenocytes.2005
- Author(s)
  Xin K-Q et al.
- Journal Title
  
  Vaccine 23, 23
  
  Pages: 2954-2955
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390129
[Journal Article] Comparison of antigen-specific cellurar immune responses between individual PBMCs and splenocytes2005
- Author(s)
  Xin, K.-Q., Ohta, S., Jounai, N., Okuda, K.
- Journal Title
  
  Vaccine 23
  
  Pages: 2954-2955
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] Prime-boost vaccination with plasmid DNA and a chimeric adenovirus type 5 vector with type 35 fiber induces persistent protective immunity against HIV2005
- Author(s)
  Xin, K.-Q.et al.
- Journal Title
  
  Gen Ther 12・24
  
  Pages: 1769-1777
- Data Source
  KAKENHI-PROJECT-17390129
[Journal Article] Repair of articular cartilage defect by autologous transplantation of basic fibroblast growth factor gene-transduced chondrocytes with adeno-associated virus vector2005
- Author(s)
  Yokoo, N., Saito, T., Uesugi, M., Kobayashi, N., Xin, K.-Q., Okuda, K., Mizukami, H., Ozawa, K., Koshino, T.
- Journal Title
  
  Arthritis Rheum 52
  
  Pages: 164-170
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] Combination of DNA vaccine and adenovirus vector by cutaneous administration induced strong HIV-specific cellular immune responses in mice2005
- Author(s)
  Takakura, M., Okuda, K., Matsuda, T., Takeshita, F., Takakura, H., Ikezawa, Z, Xin, K.-Q.
- Journal Title
  
  Vaccine 23
  
  Pages: 847-848
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] Prime-boost vaccination with plasmid DNA and a chimeric adenovirus type 5 vector with type 35 fiber induces persistent protective immunity against HIV.2005
- Author(s)
  Xin K-Q et al.
- Journal Title
  
  Gen.Ther 12, 24
  
  Pages: 1769-1777
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390129
[Journal Article] Comparison of antigen-specific cellurar immune responses between individual PBMCs and splenocytes.2005
- Author(s)
  Xin K-Q et al.
- Journal Title
  
  Vaccine 23・23
  
  Pages: 2954-2955
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390129
[Journal Article] Comparison of antigen-specific cellurar immune responses between individual PBMCs and splenocytes.2005
- Author(s)
  Xin, K.-Q.et al.
- Journal Title
  
  Vaccine 23・23
  
  Pages: 2954-2955
- Data Source
  KAKENHI-PROJECT-17390129
[Journal Article] Cross reactive protection against influenza A virus by a topically applied DNA vaccine encoding M gene with adjuvant2005
- Author(s)
  Ozaki, T., Yauchi M., Xin, K.-Q., Hirahara, F., Okuda, K.
- Journal Title
  
  Viral Immunol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] Comparison of antigen-specific cellurar immune responses between individual PBMCs and splenocytes.2005
- Author(s)
  Xin K-Q et al.
- Journal Title
  
  Vaccine (印刷中)
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] Comparison of antigen-specific cellurar immune responses between individual PBMCs and splenocytes2005
- Author(s)
  Xin K-Q et al.
- Journal Title
  
  Vaccine 23
  
  Pages: 2954-2955
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] Improvement of DNA vaccine immunogenicity by a dual antigen expression system2004
- Author(s)
  Sasaki, S., Takeshita, F., Oikawa, T., Kojima, Y., Xin, K.-Q., Okuda, K., Ishii, N.
- Journal Title
  
  Biochem Biophys Res Commun 315
  
  Pages: 38-43
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] Polygene DNA vaccine induces a high level of protective effect against HIV-vaccinia virus challenge in mice2004
- Author(s)
  Shinoda, K., Xin, K.-Q., Johna, I.N., Kojima, Y., Tamura, Y., Okada, E., Kawamoto, S., Okuda, K., Klinman, D., Okuda, K.
- Journal Title
  
  Vaccine 22
  
  Pages: 3676-3690
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] consecutive prime-boost vaccination of mice with simian immunodeficiency virus (SIV) gag/pol DNA and recombinant vaccinia virus DIs elicits effective anti-SIV immunity. A consecutive prime-boost vaccination of mice with simian immunodeficiency virus (SIV) gag/pal DNA and recombinant vaccinia virus DIs elicits effective anti-SIV immunity2004
- Author(s)
  Someya, K., Xin K.-Q., Matsuo, K., Okuda, K., Yamamoto, N., Honda, M.
- Journal Title
  
  J Virol 78
  
  Pages: 9842-9853
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] Construction and immunogenicity study of a 297-bp humanized HIV V3 DNA of an approximated last common ancestor in mice2004
- Author(s)
  Sirivichayakul, S., Tirawatnapong, T., Ruxrungtham, K., Oelrichs, R., Lorenzen, S.L., Xin, K.-Q., Okuda, K., Phanuphak, P.
- Journal Title
  
  Asian Pac J Allergy Immunol. 22
  
  Pages: 49-60
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] A DNA vaccine containing inverted terminal repeats from adeno-associated virus increases immunity to HIV2003
- Author(s)
  Xin, K.-Q., Ooki, T., Jounai, N., Mizukami, H., Hamajima, K., Kojima, Y., Ohba, K., Toda, Y,.Hirai, S., Klinman, D.M., Ozawa, K., Okuda, K.
- Journal Title
  
  J Gene Med 5
  
  Pages: 438-445
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] Immunogenicity and protective efficacy of orally administered recombinant Lactococcus lactis expressing surface-bound HIV Env2003
- Author(s)
  Xin, K.-Q., Hoshino, Y., Toda, Y., Igimi, S., Kojima, Y., Jounai, N., Ohba, K., Kushiro, A., Kiwaki, M., Hamajima, K., Klinman, D., Okuda, K.
- Journal Title
  
  Blood 102
  
  Pages: 223-228
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] Adjuvant formulations and delivery systems for DNA vaccines2003
- Author(s)
  Sasaki, S., Takeshita, F., Xin, K.-Q., Ishii, N., Okuda, K.
- Journal Title
  
  Methods 31
  
  Pages: 243-254
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] Immunogenicity and protective efficacy of orally administred recombinant Lactococcus lactis expressing surface-bound HIV Env.2003
- Author(s)
  Xin K-Q et al.
- Journal Title
  
  Blood 177・3
  
  Pages: 169-184
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] A DNA vaccine containing inverted terminal repeats from adeno-associated virus increases immunity to HIV.2003
- Author(s)
  Xin K-Q et al.
- Journal Title
  
  J Gene Med 5
  
  Pages: 438-445
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] Contribution of the rev gene to the immunogenicity of DNA vaccines targetting the envelope glycoprotein of HIV2003
- Author(s)
  Jounai, N., Okuda, K., Kojima, Y., Toda, Y., Hamajima, K., Ohba, K., Klinman, D., Xin, K.-Q.
- Journal Title
  
  J Gene Med 5
  
  Pages: 609-617
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] Chitin micro-particles (CMP) is a useful adjuvant for inducing viral specific immunity when delivered intranasally with an HIV-DNA vaccine2003
- Author(s)
  Hamajima, K., Kojima, Y., Matsui, K., Toda, Y., Jounai, N., Ozaki, T., Xin, K.-Q., Strong, P., Okuda, K.
- Journal Title
  
  Viral Immunol 16
  
  Pages: 541-547
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] Adenovirus type 5 with modified hexons induces robust trans gene-specific immune responses in mice with pre-existing immunity against adenovirus type 5.
- Author(s)
  Abe, S., Okuda, K., Ura, T., Kond o, A., Yoshida, A., Yoshizaki, S., Mizuguchi, H., Klinman, D., Shimada. M.
- Journal Title
  
  J. Gene Med. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590481
[Patent] アルツハイマー病における次世代遺伝子治療法・免疫治療法の開発2008
- Inventor(s)
  島田勝
- Industrial Property Rights Holder
  横浜市立大学
- Filing Date
  2008-01-23
- Data Source
  KAKENHI-PROJECT-19590481
[Presentation] Development of an optimized L2 -based HPV mRNA vaccine2023
- Author(s)
  島田勝
- Organizer
  第82回日本癌学会
- Data Source
  KAKENHI-PROJECT-23K08826
[Presentation] The role of apoptosis-inducing factor (AIF) in caspase-independent pathway2022
- Author(s)
  島田勝
- Organizer
  第81回日本癌学会
- Data Source
  KAKENHI-PROJECT-20K09603
[Presentation] アデノウイルス角結膜炎に対するワクチンおよび治療抗体に関する研究.2021
- Author(s)
  島田勝
- Organizer
  第57回日本眼感染症学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09603
[Presentation] Scyl2 inhibits Adenovirus release from host cells.2019
- Author(s)
  2)Masaru Shimada, Akio Yamashita, Akiko Okayama, Hisashi Hirano, Nobuhisa Mizuki, Kenji Okuda.
- Organizer
  第６７回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-17K11288
[Presentation] 緑膿菌角膜炎に対する新規膜小胞ワクチンの開発2019
- Author(s)
  島田　勝、伊藤　沙織、盛　理子、竹内正樹、福島　淳、水木　信久、奥田　研爾
- Organizer
  第５３回緑膿菌感染症研究会
- Data Source
  KAKENHI-PROJECT-17K11288
[Presentation] Vaccine development against Pseudomonas aeruginosa keratitis using membrane vesicles.2019
- Author(s)
  1)Masaru Shimada, Saori Ito, Michiko Mori, Jun Fukushima, Kenji Okuda, Nobuhisa Mizuki.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K11288
[Presentation] Development of a vaccine against adenovirus-conjunctivitis in a mouse model2018
- Author(s)
  Masaru Shimada, Michiko Mori, Saori Ito, Kenji Kawazoe, Yoshitaka Miyanaga, Kenji Okuda, Nobuhisa Mizuki.
- Organizer
  第７7回日本癌学会
- Data Source
  KAKENHI-PROJECT-17K11288
[Presentation] Development of a vaccine against adenovirus-conjunctivitis in a mouse model2018
- Author(s)
  Masaru Shimada, Michiko Mori, Saori Ito, Kenji Kawazoe, Yoshitaka Miyanaga, Kenji Okuda, Nobuhisa Mizuki.
- Organizer
  第66回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-17K11288
[Presentation] 緑膿菌角膜炎に対する新規膜小胞ワクチンの開発2018
- Author(s)
  ①石戸　みづほ、盛　理子、島田　勝、福島　淳、水木　信久
- Organizer
  第55回日本眼感染症学会
- Data Source
  KAKENHI-PROJECT-17K11288
[Presentation] アデノウイルス角結膜炎モデルマウスを用いたワクチン開発2018
- Author(s)
  ②盛　理子、島田　勝、宮永　嘉隆、川添　賢志、水木　信久
- Organizer
  第55回日本眼感染症学会
- Data Source
  KAKENHI-PROJECT-17K11288
[Presentation] The human papillomavirus E6 protein targets apoptosis-inducing factor (AIF) for degradation2018
- Author(s)
  Masaru Shimada, Akio Yamashita, Motohide Ichino, Takao Kinjo, Kenji Okuda.
- Organizer
  2nd International Conference on Oncology and Radiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11288
[Presentation] アデノウイルス結膜炎マウスモデルの樹立およびワクチンの開発2017
- Author(s)
  盛　理子、島田勝、宮永嘉隆、川添賢志、河越龍方、水木信久
- Organizer
  第54回日本眼感染症学会
- Data Source
  KAKENHI-PROJECT-17K11288
[Presentation] アデノウイルス結膜炎における感染マウスモデルの樹立2017
- Author(s)
  ③島田勝、盛理子、川添賢志、宮永嘉孝、奥田研爾、水木信久
- Organizer
  第65回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-17K11288
[Presentation] アデノウイルス結膜炎マウスモデルの樹立およびワクチンの開発2017
- Author(s)
  島田勝、盛理子、川添賢志、宮永嘉孝、水木信久
- Organizer
  第７６回日本癌学会
- Data Source
  KAKENHI-PROJECT-17K11288
[Presentation] The importance of apoptosis-inducing factor (AIF) in HPV E6-mediated apoptosis.2016
- Author(s)
  Masaru Shimada, Akio Yamashita, Akiko Okayama, Takao Kinjo, Motohide Ichino, Hisashi Hirano, Kenji Okuda.
- Organizer
  第75回日本癌学会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26462531
[Presentation] Prophylaxis and treatment of Alzheimer’s disease by delivery of an adeno associated virus encoding a monoclonal antibody targeting the amyloid beta protein.2015
- Author(s)
  Masaru Shimada and Kenji Okuda.
- Organizer
  7th Middle East-Global summit and Expo on Vaccines & Vaccination,
- Place of Presentation
  Ｄｕｂａｉ, UAE
- Year and Date
  2015-09-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462531
[Presentation] HPV E6 and E7 inhibit apoptosis inducing factor 1 (AIFM1)-mediated apoptosis through different pathway.2015
- Author(s)
  Masaru Shimada, Akio Yamashita, Akiko Okayama, Hisashi Hirano, Kenji Okuda.
- Organizer
  第63回日本ウイルス学会
- Place of Presentation
  福岡 (福岡国際会議場）
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-26462531
[Presentation] Designed recombinant adenovirus type 5 vector induced cross-reactive neutralizing antibodies against HIV-1.2008
- Author(s)
  浦剛博, 八島さやか, 吉田篤司, 島田勝, 奥田研爾
- Organizer
  日本免疫学会学術集会・総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590481
[Presentation] using Ad5/35 and MVA vectors on SIV-infection of rhesus monkeys undergoing anti-retroviral therapy2008
- Author(s)
  島田勝, 浦剛博, 吉田篤司, 奥田研爾
- Organizer
  第38回日本免疫学会学術集会・総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590481
[Presentation] Designed recombinant adenovirus type 5 vector induced cross-reactive neutralizing antibodies against HIV-12008
- Author(s)
  浦剛博, 八島さやか, 吉田篤司, 島田勝, 奥田研爾
- Organizer
  第38回日本免疫学会学術集会・総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590481
[Presentation] 抗5型アデノウイルス抗体を有するスに対するヘキソン改変5型アデノウイルスベクターの有効性の検討2008
- Author(s)
  島田勝, 阿部晋也, 井野麻美, 吉田篤司, 浦剛博, 吉崎慎二, 水口裕之, 奥田研爾
- Organizer
  第56回日本ウイルス学会学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-19590481
[Presentation] HIV遺伝子搭載アデノウイルスベクターを基盤としたHIVワクチン最適化に向けた検討2008
- Author(s)
  庄司正樹, 井野麻美, 吉田篤司, 水口裕之, 島田勝, 奥田研爾
- Organizer
  第56回日本ウイルス学会学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-19590481
[Presentation] 抗5型アデノウイルス抗体を有するマウスに対するヘキソン改変5型アデノウイルスベクターの有効性2008
- Author(s)
  阿部晋也, 井野麻美, 吉田篤司, 島田勝
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590481
[Presentation] 抗5型アデノウイルス抗体を有するマウスに対するヘキソン改変5型アデノウイルスベクターの有効性の検討2008
- Author(s)
  島田勝, 阿部晋也, 井野麻美, 吉田篤司, 浦剛博, 吉崎慎二, 水口裕之, 奥田研爾
- Organizer
  第56回日本ウイルス学会学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-19590481
[Presentation] 抗アデノウイルス抗体誘導マウスにおけるヘキソン改変型アデノベクターによる免疫誘導能の解析2008
- Author(s)
  井野麻美, 阿部晋也, 浦剛博, 吉崎慎二, 吉田篤司, 島田勝, 奥田研爾
- Organizer
  第22回日本エイズ学会学術集会・総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590481
[Presentation] 抗5型アデノウイルス抗体を有するマウスに対するヘキソン改変5型アデノウイルスベクターの有効性。2008
- Author(s)
  阿部晋也, 井野麻美, 吉田篤司, 島田勝
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590481
[Presentation] HIV遺伝子搭載アデノウイルスベクターによる免疫誘導能の比較2008
- Author(s)
  庄司正樹, 浦剛博, 吉田篤司, 水口裕之, 島田勝, 奥田研爾
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590481
[Presentation] サルでのウイルスベクターワクチンを用いた治療効果の検討2007
- Author(s)
  島田勝, 井野麻美, 吉田篤司, 奥田研爾
- Organizer
  第55回日本ウイルス学会
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-19590481
[Presentation] サルでのウイルスベクターワクチンを用いた治療効果の検討2007
- Author(s)
  島田勝, 井野麻美, 吉田篤司, 奥田研爾
- Organizer
  第21回日本エイズ学会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-19590481
[Presentation] ヒトパピローマウイルスにおける発がん機構の解明
- Author(s)
  島田勝、山下暁朗、斎藤真奈美、岡山明子、平野久
- Organizer
  第73回日本癌学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26462531
[Presentation] The role of apoptosis inducing factor 1 (AIFM1) in HPV-inducing cancer
- Author(s)
  Masaru Shimada, Akio Yamashita, Manami Saito, Akiko Okayama, Hisashi Hirano.
- Organizer
  Keystone Symposia, Viruses and Human Cancer
- Place of Presentation
  Montana, USA
- Year and Date
  2015-03-26 – 2015-04-01
- Data Source
  KAKENHI-PROJECT-26462531
[Presentation] ヒトパピローマウイルスの感染による発がん機構の解明
- Author(s)
  島田勝、山下暁朗、斎藤真奈美、岡山明子、平野久
- Organizer
  第62回日本ウイルス学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-26462531

1. 山下暁朗 (20405020)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
2. HAMAJIMA Kenji (00114611)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
3. OKUDA Kenji (40124862)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
4. SHIRAKAWA Toshiro (70335446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KATAYAMA Tkakane (70346104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. AOKI Ichiro (00184028)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. FUKUSHIMA Jun (00181256)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KAWAI Kosei (20305452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OZAWA Keiya (30137707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SAITO Tomoyuki (30170517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAKESHITA Fumihiko (60333572)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 河合孝誠 (00264656)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 金城貴夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shimada Masaru 島田 勝

SHIMADA Masaru 島田 勝

XIN Ke Qin 忻 克勤

忻 克〓 キン カッキン

Research Projects

Research Products

Co-Researchers

ゲノム編集技術を使用したヒトパピローマウイルスの感染機構に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Elucidation of the cell infection mechanism of human papilloma virus using genome editing techniquePrincipal Investigator

Principal Investigator

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Review Section

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A study for human papillomavirus (HPV) infection mechanismPrincipal Investigator

Principal Investigator

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A global study for HPV-cell infection mechanismPrincipal Investigator

Principal Investigator

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Novel oral vaccine using genetically engineering bifidobacterium displaying antigen on its cell-surface

Principal Investigator

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Adeno-associate virus (AAV) induces apoptosis of HIV-infected cellsPrincipal Investigator

Principal Investigator

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Novel Vaccines against Pseudomonas aeruginosa and Other Microorganisms

Principal Investigator

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Developmental research of new generation DNA vaccine against microorganism using synthesized DNA

Principal Investigator

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Research Institution

The adjuvant effects of CpG motif and activated large number of activated-T lymphocytes on immunoresponses.

Principal Investigator

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Gene transfer to periosteum-derived cells for cartilage repair

Principal Investigator

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Research Institution

Enhancement of protection against various microbial infection by the modification of dominance of Thl or Th2 immune responses

Principal Investigator

Project Period (FY)

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Research Institution

肝のアポトーシスか、ネクローシスか:カドミウム腎障害発症機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Biodistribution and immunity of adenovirus 5/35 and modified vaccinia Ankara vector vaccines against human immunodeficiency virus 1 clade C2022

Shimada Masaru 島田勝

SHIMADA Masaru 島田勝

XIN Ke Qin 忻克勤

忻克〓キンカッキン