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TAKAHASHI Kohta  高橋 考太

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高橋 考太  タカハシ コウタ

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Researcher Number 40303804
External Links
Affiliation (Current) 2025: 北海学園大学, 工学部, 教授
Affiliation (based on the past Project Information) *help 2002 – 2008: 久留米大学, 分子生命科学研究所, 教授
2004: 久留米大学, 教授
2000 – 2001: 京都大学, 生命科学研究科, 助手
1999: 京都大学, 大学院・生命科学研究科, 助手
Review Section/Research Field
Principal Investigator
Biological Sciences / Cell biology / Cell biology
Except Principal Investigator
Biological Sciences
Keywords
Principal Investigator
分裂酵母 / セントロメア / CENP-A / 染色体 / ヌクレオソーム / チェックポイント / 染色体分配 / 異数体 / Nucleosome / Fission yeast … More / Centromere / Chromosome / siRNA / Mad2 / がん / ヘテロクロマチン / 細胞周期 / 分裂期 / 紡錘体 / 中心体 / 復帰変異株 / 薬剤耐性マーカー遺伝子 / ゲノム改変 / ネオセントロメア / GATA / キネトコア / クロマチン / 有糸分裂 / ヒストン … More
Except Principal Investigator
染色体 / Mis6 / Mad2 / スピンドル / M期チェックポイント / 動原体 / 分裂酵母 / 細胞応答 / クロマチン構造 / セントロメア / Kin-Iキネシン / Kin1キネシン / 紡錘体 / チェックポイント / 紡鐸体 / キネトコア Less
  • Research Projects

    (14 results)
  • Research Products

    (46 results)
  • Co-Researchers

    (3 People)
  •  セントロメア新生機構の分子解剖

    • Principal Investigator
      石井 浩二郎
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kurume University
  •  Kin-IキネシンによるM期チェックポイント・スピンドル形成制御機構の解明

    • Principal Investigator
      齋藤 成昭
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kurume University
  •  ヒトセントロソーム蛋白質Molのチェクポイント伝達経路における役割の解明Principal Investigator

    • Principal Investigator
      高橋 考太
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kurume University
  •  分裂酵母Mis6動原体複合体が果たすM期チェックポイント機能の解明

    • Principal Investigator
      齋藤 成昭
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kurume University
  •  Molecular Properties of Nuclear Architecture and Centromere Function for Faithful Chromosome SegregationPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Kohta
    • Project Period (FY)
      2004 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kurume University
  •  人為的ゲノム改変によるネオセントロメア創生の試みPrincipal Investigator

    • Principal Investigator
      高橋 考太
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cell biology
    • Research Institution
      Kurume University
  •  セントロメア機能制御系の構築を軸にしたゲノム伝達操作技術の開発Principal Investigator

    • Principal Investigator
      高橋 考太
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kurume University
  •  がん悪性化に関与する異数体生成の分子メカニズムの解明Principal Investigator

    • Principal Investigator
      高橋 考太
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kurume University
  •  スピンドルチェックポイントに感知されない異数体生成の分子メカニズムの解明Principal Investigator

    • Principal Investigator
      高橋 考太
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kurume University
  •  Molecular basis of centromeric chromatin required for equal chromosome segregationPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Kohta
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      Kurume University
  •  スピンドルチェックポイントに感知されない異数体生成の分子メカニズムの解明Principal Investigator

    • Principal Investigator
      高橋 考太
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  セントロメア機能制御系の構築を軸にしたゲノム伝達操作技術の開発Principal Investigator

    • Principal Investigator
      高橋 考太
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  がん悪性化に関与する異数体生成の分子メカニズムの解明Principal Investigator

    • Principal Investigator
      高橋 考太
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  進化的に保存された動原体特異的ヒストンCENP-Aの分裂酵母ホモログの機能解明Principal Investigator

    • Principal Investigator
      高橋 考太
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Cell biology
    • Research Institution
      Kyoto University

All 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation Book Patent

  • [Book] 動原体.酵母のすべて系統、細胞から分子まで(大隈良典・下田親編)2007

    • Author(s)
      高橋考太
    • Publisher
      シュプリンガー・ジャパン
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Book] 細胞核の世界(M 期染色体動態の制御機構、蛋白質核酸酵素増刊)2006

    • Author(s)
      高橋 考太
    • Total Pages
      9
    • Publisher
      共立出版株式会社
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Book] チェックポイント-細胞周期の監視点、細胞周期集中マスター(北側雅敏 編)2006

    • Author(s)
      齋藤 成昭, 高橋 考太
    • Total Pages
      11
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Book] Chromosome cohesion and segregation. The Molecular Biology in Fission Yeast (Egel R., Ed.)2004

    • Author(s)
      Takahashi K, Yanagida M.
    • Publisher
      Springer-Verlag Inc.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380334
  • [Book] Chromosome cohesion and segregation. In The Molecular Biology in Fission Yeast (Egel R., Ed.)2004

    • Author(s)
      Takahashi K
    • Total Pages
      450
    • Publisher
      Springer-Verlag Inc.
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380334
  • [Book] The Molecular Biology in Fission Yeast (Egel R., Ed.)2004

    • Author(s)
      Kohta Takahashi, and Mitsuhiro Yanagida. Chromosome cohesion and segregation
    • Publisher
      Springer-Verlag Inc.
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Book] Chromosome cohesion and segregation. in "The molecular biology in fission yeast"2003

    • Author(s)
      Kohta Takahashi
    • Total Pages
      450
    • Publisher
      Egel R.,Ed.,Springer-Verlag
    • Data Source
      KAKENHI-PROJECT-14380334
  • [Book] Chromosome cohesion and segregation. in "The molecular biology in fission yeast"2003

    • Author(s)
      Kohta Takahashi
    • Total Pages
      450
    • Publisher
      Egel R., Ed., Springer-Verlag
    • Data Source
      KAKENHI-PROJECT-15657048
  • [Book] Chromosome cohesion and segregation. in "The molecular biology in fission yeast"2003

    • Author(s)
      Kohta Takahashi
    • Total Pages
      450
    • Publisher
      Egel R., Ed., Springer-Verlag
    • Data Source
      KAKENHI-PROJECT-16021255
  • [Journal Article] Heterochromatin integrity affects chromosome reorganization after centromere dysfunction2008

    • Author(s)
      Kojiro Ishii, Yuki Ogiyama, Yuji Chikashige, Saeko Soejima, Fumie Masuda, Tatsuyuki Kakuma, Yasushi Hiraoka, and Kohta Takahashi
    • Journal Title

      Science 321

      Pages: 1088-1091

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Journal Article] Biphasic incorporation of centromeric histone CENP-A in fission yeast2008

    • Author(s)
      Yuko Takayama, Hiroshi Sato, Shigeaki Saitoh, Yuki Ogiyama, Fumie Masuda, Kohta Takahashi
    • Journal Title

      Molecular Biology of the Cell 19

      Pages: 682-690

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Journal Article] Dual regulation of Mad2 localization on kinetochores by Bub1 and Dam1/DASH that ensure proper spindle interaction2008

    • Author(s)
      Shigeaki Saitoh, Yasuyo Kobayashi, Yuki Ogiyama, and Kohta Takahashi
    • Journal Title

      Mol. Biol. Cell 19

      Pages: 3885-3897

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Journal Article] Biphasic incorporation of centromeric histone CENP-A in fission yeast2008

    • Author(s)
      Yuko Takayama, Hiroshi Sato, Shigeaki Saitoh, Yuki Ogiyama, Fumie Masuda, and Kohta Takahashi
    • Journal Title

      Mol. Biol. Cell 19

      Pages: 682-690

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Journal Article] Differential regulation of repeated histone genes during the fission yeast cell cycle2007

    • Author(s)
      Yuko Takayama, and Kohta Takahashi
    • Journal Title

      Nucleic Acids Res 35

      Pages: 3223-3237

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Journal Article] The fission yeast DASH complex is essential for satisfying the spindle assembly checkpoint induced by defects in the inner-kinetochore proteins2007

    • Author(s)
      小林妥世, 齋藤成昭, 荻山友貴, 副島朗子, 高橋考太
    • Journal Title

      Gene to Cells 12

      Pages: 311-328

    • Data Source
      KAKENHI-PROJECT-17049026
  • [Journal Article] Differential regulation of repeated histone genes during the fission yeast cell cycle2007

    • Author(s)
      Yuko Takayama, Kohta Takahashi
    • Journal Title

      Nucleic Acids Research 35

      Pages: 3223-3237

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Journal Article] The fission yeast DASH complex is essential for satisfying the spindle assembly checkpoint induced by defects in the inner-kinetochore proteins2007

    • Author(s)
      Yasuyo Kobayashi, Shigeaki Saitoh, Yuki Ogiyama, Saeko Soejima, and Kohta Takahashi
    • Journal Title

      Genes Cells 12

      Pages: 311-28

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Journal Article] BAF53/Arp4 homolog Alp5 in fission yeast is required for histone H4 acetylation, kinetochore-spindle attachment, and gene silencing at centromere.2005

    • Author(s)
      Minoda A, Saitoh S, Takahashi K, Toda T.
    • Journal Title

      Molecular Biology of the Cell 16

      Pages: 316-327

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380334
  • [Journal Article] Two distinct pathways responsible for the loading of CENP-A to centromeres in the fission yeast cell cycle.2005

    • Author(s)
      Kohta Takahashi
    • Journal Title

      Philos. Trans. R. Soc. Lond. B. Biol. Sci. in press

    • Data Source
      KAKENHI-PROJECT-15657048
  • [Journal Article] Two distinct pathways responsible for the loading of CENP-A to centromeres in the fission yeast cell cycle.2005

    • Author(s)
      Takahashi K, Takayama Y, Masuda F, Kobayashi Y, Saitoh S
    • Journal Title

      Philosophical Transactions of the Royal Society B 360

      Pages: 595-607

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380334
  • [Journal Article] Two distinct pathways responsible for the loading of CENP-A to centxomeres in the fission yeast cell cycle.2005

    • Author(s)
      Kohta Takahashi
    • Journal Title

      Philos. Trans. R. Soc. Lond. B. Biol. Sci. in press

    • Data Source
      KAKENHI-PROJECT-16021255
  • [Journal Article] Spindle checkpoint signaling requires the Mis6 kinetochore subcomplex, which interacts with Mad2 and mitotic spindles2005

    • Author(s)
      Shigeaki Saitoh, Kojiro Ishii, Yasuyo Kobayashi, and Kohta Takahashi
    • Journal Title

      Mol. Biol. Cell 16

      Pages: 3666-3677

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Journal Article] Two distinct pathways responsible for the loading of CENP-A to centromeres in the fission yeast cell cycle.2005

    • Author(s)
      Takahashi K
    • Journal Title

      Philosophical Transactions of the Royal Society B 360

      Pages: 595-607

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380334
  • [Journal Article] Two distinct pathways responsible for the loading of CENP-A to centromeres in the fission yeast cell cycle.2005

    • Author(s)
      Kohta Takahashi
    • Journal Title

      Philos. Trans. R. Soc. Lond. B. Biol. Sci. in press

    • Data Source
      KAKENHI-PROJECT-16084207
  • [Journal Article] Two distinct pathways responsible for the loading of CENP-A to centromeres in the fission yeast cell cycle.2005

    • Author(s)
      Kohta Takahashi
    • Journal Title

      Philos.Trans.R.Soc.Lond.B.Biol.Sci. in press

    • Data Source
      KAKENHI-PROJECT-14380334
  • [Journal Article] Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres.2004

    • Author(s)
      Hayashi T, Fujita Y, Iwasaki O, Adachi Y, Takahashi K, Yanagida M.
    • Journal Title

      Cell 118

      Pages: 715-729

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380334
  • [Journal Article] An interactive gene network for securin-separase, condensin, cohesin, Dis1/Mtc1 and histones constructed by mass transformation.2004

    • Author(s)
      Yuasa T, Hayashi T, Ikai N, Katayama T, Aoki K, Obara T, Toyoda Y, Maruyama T, Kitagawa D, Takahashi K, Nagao K, Nakaseko Y, Yanagida M.
    • Journal Title

      Genes to Cells 9

      Pages: 1069-1082

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380334
  • [Journal Article] Does a GATA factor make a bed for centromeric nucleosomes?2003

    • Author(s)
      Chen ES, Yanagida M, Takahashi K.
    • Journal Title

      Cell Cycle 12

      Pages: 277-278

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380334
  • [Journal Article] A cell cycle-regulated GATA factor promotes centromeric localization of CENP-A in fission yeast.2003

    • Author(s)
      Chen ES, Saitoh S, Yanagida M, Takahashi K.
    • Journal Title

      Molecular Cell 11

      Pages: 175-187

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380334
  • [Journal Article] Requirement of chromatid cohesion proteins rad21/scc1 and mis4/scc2 for normal spindle-kinetochore interaction in fission yeast.2002

    • Author(s)
      Toyoda Y, Furuya K, Goshima G, Nagao K, Takahashi K, Yanagida M.
    • Journal Title

      Curr Biology 12

      Pages: 347-358

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380334
  • [Journal Article] Spindle checkpoint signaling requires the Mis6 kinetochore subcomplex, which interacts with Mad2 and mitotic spindles.

    • Author(s)
      Saitoh S, Ishii K, Kobayashi Y, Takahashi K
    • Journal Title

      Molecular Biology of the Cell (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380334
  • [Patent] RNA interference induction element and use thereof2006

    • Inventor(s)
      石井浩二郎, 高橋考太
    • Industrial Property Rights Holder
      久留米大学, 科学技術振興機構
    • Filing Date
      2006-05-15
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Patent] RNA interference induction element and use thereof2006

    • Inventor(s)
      石井浩二郎, 高橋考太
    • Industrial Property Rights Holder
      久留米大学, 科学技術振興機構
    • Filing Date
      2006-05-15
    • Data Source
      KAKENHI-PROJECT-18058022
  • [Patent] RNA干渉誘導エレメント及びその用途2005

    • Inventor(s)
      石井浩二郎、高橋考太
    • Industrial Property Rights Holder
      久留米大学、科学技術振興機構
    • Industrial Property Number
      2005-145876
    • Filing Date
      2005-05-18
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Presentation] Heterochromatin integrity affects chromosome reorganization after chentromere dysfunction2008

    • Author(s)
      Takahashi K
    • Organizer
      International Symposium on Chromosome Dynamics in Ise
    • Place of Presentation
      Ise
    • Year and Date
      2008-05-28
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Presentation] Molecular Mechanism on Chromosome Reorganization2008

    • Author(s)
      高橋考太
    • Organizer
      大阪大学蛋白質研究所シンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2008-10-31
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Presentation] Chromosome reorganization after centromere dysfunction2008

    • Author(s)
      Takahashi K
    • Organizer
      EMBO workshop "Chromosome Segregation : Centromere & Kinetochore"
    • Place of Presentation
      Bordeaux
    • Year and Date
      2008-09-29
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Presentation] Heterochromatin Integrity Affects Chromosome Reorganisation after Centromere Dysfunction2008

    • Author(s)
      Takahashi K
    • Organizer
      33rd FEBS Congress & 11th IUBMB Conference "Chromosome Structure, Movements and Insulators"
    • Place of Presentation
      Athens
    • Year and Date
      2008-06-29
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Presentation] カリオタイプ変動の分子機構2008

    • Author(s)
      高橋考太
    • Organizer
      大阪大学蛋白質研究所セミナー"染色体機能とその病態"
    • Place of Presentation
      大阪府吹田市
    • Year and Date
      2008-03-14
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Presentation] Chromosome reorganization after centromere dysfunction2008

    • Author(s)
      Kohta Takahashi
    • Organizer
      EMBO workshop, Chromosome Segregation: Centromere & Kinetochore
    • Place of Presentation
      Bordeaux
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Presentation] セントロメア破壊に起因するカリオタイプ変動の制御機構2008

    • Author(s)
      高橋考太
    • Organizer
      第25回染色体ワークショップ
    • Place of Presentation
      静岡県熱海市
    • Year and Date
      2008-01-31
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Presentation] 分裂酵母セントロメア破壊株の分離2007

    • Author(s)
      高橋考太
    • Organizer
      染色体学会・染色体コロキウム合同年会
    • Place of Presentation
      神奈川県葉山
    • Year and Date
      2007-11-27
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Presentation] Neocentromere formation and telomere fusion:Two modes of survivors from centromere disruption2007

    • Author(s)
      Kohta Takahashi
    • Organizer
      4th International Fission Yeast Meeting
    • Place of Presentation
      Copenhagen
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Presentation] Neocentromere formation and telomere fusion:two modes of survivors from centromere disruption2007

    • Author(s)
      高橋考太
    • Organizer
      International fission yeast meeting
    • Place of Presentation
      Copenhagen,Denmark
    • Year and Date
      2007-06-13
    • Data Source
      KAKENHI-PROJECT-18058022
  • [Presentation] Neocentromere formation and telomere fusion: Two modes of survivors from centromere disruption2007

    • Author(s)
      Kohta Takahashi
    • Organizer
      The 4th International Fission Yeast Meeting
    • Place of Presentation
      Copenhagen
    • Data Source
      KAKENHI-PROJECT-16084207
  • [Presentation] Two distinct cell cycle phases responsible for centromere localization of CENP-A in fission yeast2004

    • Author(s)
      Kohta Takahashi
    • Organizer
      The Royal Society discussion meeting on chromosome segregation
    • Place of Presentation
      London
    • Data Source
      KAKENHI-PROJECT-16084207
  • 1.  齋藤 成昭 (30352123)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 2.  ISHII Kojiro (40360276)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 3.  FUKAGAWA Tatsuo (60321600)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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