ISHII Takahiro 石井孝広

Researcher Number	40303812
Other IDs
Affiliation (based on the past Project Information) *help	2011: 京都大学, 医学研究科, 研究員 2011: 京都大学, 大学院・医学研究科, 研究員 2010: 京都大学, 医学研究科, 客員研究員 2009: Kyoto University, 医学研究科, 研究員 2007 – 2009: Kyoto University, 医学研究科, 准教授 … More 2005 – 2006: Kyoto University, Graduate School of Medicine, Associate Professor, 医学研究科, 助教授 2000 – 2004: 京都大学, 医学研究科, 助手 1999: 京都大学, 大学院・医学研究科, 助手 Less
Review Section/Research Field	Principal Investigator General physiology / General physiology / 神経・脳内生理学 Except Principal Investigator Biological Sciences / Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies
Keywords	Principal Investigator HCN / Ih / チャネル / 過分極 / システイン残基 / 点変異 / 電位センサー / 活性化速度 / キメラ / tetracycline … More / homologous recombination / channel / hyperpolarization / 相同組換え / 相同組替 / テトラサイクリン / 相同組換 / ペースメーカー / 変異体 / cAMP / ジスルフィド結合 / ゲート機構 / 多量体 / イオンチャネル / 分子生理学 / パッチクランプ / cDNA / カルシウムチャネル / カリウムチャネル / Ihチャネル / 聴覚 / 蝸牛神経核 … More Except Principal Investigator HCN / SK / IK / 揮発性麻酔薬 / 大細胞核 / 蝸牛神経核 / シナプス / 層状核 / 特徴抽出 / H電流 / 同時検出 / 音源定位 / 聴覚 / volatile anesthetics / Ca-activated K channel / hyperpolarization-activated / Ca依存性Kチャネル / 過分極誘発型チャネル / calpain / FRET / K電流 / 両耳間時間差 / 音圧 / 上オリーブ核 / 角状核 / 方位選択性 / 位相差 / 両耳間音圧差 / 外側毛帯核 / 両耳間時差 / 表面プラズモン共鳴 / ATP / ルシフェラーゼ / 位相応答特性 / シナプス伝達 / 角状角 / lh電流 / MNTB / 低闘値K電流 / 低閾値K電流 / 神経回路 / 低閾地K電流 Less

Structure-function studies of voltage-sensors and cAMP-dependent activation in HCN channelsPrincipal Investigator
- Principal Investigator
  
  ISHII Takahiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kyoto University
Studies of voltage sensor and ion permeability in HCN channelsPrincipal Investigator
- Principal Investigator
  
  ISHII Takahiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kyoto University
Auditory Feature Extraction and Processing
- Principal Investigator
  
  OHMORI Harunori
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
表面プラズモン共鳴を利用した揮発性麻酔薬とタンパク質との特異的結合定数の測定
- Principal Investigator
  
  NAMBA Tsunehisa
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kyoto University
Studies on physiological significance of hyperpolarization-activated cation channelsPrincipal Investigator
- Principal Investigator
  
  ISHII Takahiro
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Graduate School of Medicine, Kyoto University
過分極で活性化される陽イオンチャネルの構造と機能に関する研究Principal Investigator
- Principal Investigator
  
  石井孝広
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Kyoto University
Action and mechanism of general anesthtics on subtypes of K channels
- Principal Investigator
  
  NAMBA Tsunehisa
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  KYOTO UNIVERSITY
聴神経核における特徴抽出回路の形成と機能
- Principal Investigator
  
  OHMORI Harunori
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
ニワトリ聴覚伝導路における特徴抽出機構の電気生理学的及び分子生物学的解析Principal Investigator
- Principal Investigator
  
  石井孝広
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  神経・脳内生理学
- Research Institution
  Kyoto University

All 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation Patent

[Journal Article] Controlled Release of Matrix Metalloproteinase-1 Plasmid DNA Prevents Left Ventricular Remodeling in Chronic Myocardial Infarction of Rats2011
- Author(s)
  Xue Lin, Hikari Jo, Takahiro M Ishii, Masatoshi Fujita, Michael Fu, Keiichi Tambara, Masaya Yamamoto, Yasuhiko Tabata, Masashi Komeda, and Satoshi Matsuoka
- Journal Title
  
  Circulation Journal
  
  Volume: 73 Pages: 2315-2321
- URL
  http://dx.doi.org/10.1016/j.bbadis.2011.07.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590232
[Journal Article] Controlled Release of Matrix Metalloproteinase-1 Plasmid DNA Prevents Left Ventricular Remodeling in Chronic Myocardial Infarction of Rats2009
- Author(s)
  Xue Lin, Hikari Jo, Takahiro M Ishii, Masatoshi Fujita, Michael Fu, Keiichi Tambara, Masaya Yamamoto, Yasuhiko Tabata, Masashi Komeda, Satoshi Matsuoka
- Journal Title
  
  Circulation Journal 73
  
  Pages: 2315-2321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590232
[Journal Article] Tryptophan scanning mutagenesis in the S1 domain of mammalian HCN channel reveals residues critical for voltage-gated activation2007
- Author(s)
  Takahiro M. Ishii, Noriyuki Nakashima, and Harunori Ohmori
- Journal Title
  
  J. Physiology 579.2
  
  Pages: 291-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590208
[Journal Article] Misexpression of Sox9 in mouse limb bud mesenchyme induces polydactyly and rescues hypodactyly mice2007
- Author(s)
  Haruhiko Akiyama, H. Scott Stadler, James F. Martin, Takahiro M. Ishii, Philip A. Beachy, Takashi Nakamura, and Benoit de Crombruggh
- Journal Title
  
  Matrix Biology 26
  
  Pages: 224-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590208
[Journal Article] Peripheral N- and C-terminal domains determine deactivation kinetics of HCN channels2007
- Author(s)
  Takahiro M Ishii, Noriyuki Nakashima, Kenji Takatsuka &
- Journal Title
  
  BBRC 359-3
  
  Pages: 592-598
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17023027
[Journal Article] HCN and Cav3 ion Channels Confer Automaticity of Embryonic Stem Cell-derived Cardiomyocytes"2007
- Author(s)
  Kentoku Yanagi, Makoto Takano, Genta Narazaki, Hideki Uosaki, Takuhiro Hoshino, Takahiro Ishii, Takurou Misaki, and Jun K Yamashita
- Journal Title
  
  Stem Cells 25
  
  Pages: 2712-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590208
[Journal Article] Mechanistic basis for the pathogenesis of long QT syndrome associated with a common splicing mutation in KCNQ1 gene2007
- Author(s)
  Keiko Tsuji, Masaharu Akao, Takahiro M. Ishii, Seiko Ohno, Takeru Makiyama, Kotoe Takenaka, Takahiro Doi, Yoshisumi Haruna, Hidetada Yoshida, Toshihiro Nakashima, Toru Kita, and Minoru Horie
- Journal Title
  
  Journal of Molecular and Cellular Cardiolog 42
  
  Pages: 662-669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590208
[Journal Article] HCN and Cav3 ion Channels Confer Automaticity of Embryonic Stem Cell-derived Cardiomyocytes2007
- Author(s)
  Kentoku Yanagi, Makoto Takano, Genta Narazaki, Hideki Uosakii, Takuhiro Hoshino, Takabiro Ishii, Takurou Misaki, and Jun K. Yamashita
- Journal Title
  
  Stem Cells 25
  
  Pages: 2712-2719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590208
[Journal Article] NRSF regulates the developmental and hypertrophic changes of HCN4 transcription in rat cardiac myocytes2007
- Author(s)
  Shinobu Kuratomi, Akiko Kuratomi, Koichiro Kuwahara, Takahiro M. Ishii, Kazuwa Nakao, Yoshihiko Saito, and Makoto Takano
- Journal Title
  
  Biochem. Biophys. Res. Comm. 353
  
  Pages: 67-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590208
[Journal Article] NRSF regulates the developmental and hypertrophic changes of HCN4 transcription in rat cardiac myocytes2007
- Author(s)
  Shinobu Kuratomi, Akiko Kuratomi, Koichiro Kuwahara, Takahiro M. Ishii, Kazuwa Nakao, Yoshihiko Saito, and Makoto Takano
- Journal Title
  
  Biochem. Biophys. Res. Comm 353
  
  Pages: 67-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590208
[Journal Article] Peripheral N-and C-terminal domains determine deactivation kinetics of HCN channels2007
- Author(s)
  Takahiro M. Ishii, Noriyuki Nakashima, Kenji Takatsuka, and Harunori Ohmori
- Journal Title
  
  Biochem. Biophys. Res. Comm. 359
  
  Pages: 592-598
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590208
[Journal Article] Peripheral Nand C-terminal domains determine deactivation kinetics of HCN channels2007
- Author(s)
  Takahiro M. Ishii, Noriyuki Nakashima, Kenji Takatsuka, and Harunori Ohmori
- Journal Title
  
  Biochem. Biophys. Res. Comm 359
  
  Pages: 592-598
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590208
[Journal Article] Mechanistic basis for the pathogenesis of long QT syndrome associated with a common splicing mutation in KCNQ1 gene2007
- Author(s)
  Keiko Tsuji, Masaharu Akao, Takahiro M. Ishii, Seiko Ohno, Takeru Makiyama, Kotoe Takenaka, Takahiro Doi, Yoshisumi Haruna, Hidetada Yoshida, Toshihiro Nakashima, Toru Kita, and Minoru Horie
- Journal Title
  
  Journal of Molecular and Cellular Cardiology 42
  
  Pages: 662-669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590208
[Journal Article] Tytophan-scanning mutagenesis in the Sl domain of mammalian HCN channel reveals residues critical for2007
- Author(s)
  Ishii, M. T., Nakashima, N. & Ohmori, H
- Journal Title
  
  J. Physiology 579.2
  
  Pages: 291-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17023027
[Journal Article] Tryptophan scanning mutagenesis in the S1 domain of mammalian HCN channel reveals residues critical for voltage-gated activation2007
- Author(s)
  Takahiro M. Ishii, Noriyuki Nakashima, and Harunori Ohmori
- Journal Title
  
  J. Physiology 579
  
  Pages: 291-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590208
[Journal Article] Axonal site of spike initiation enhances auditory coincidence detection2006
- Author(s)
  Kuba, H., Ishii, M.T., Ohmori, H
- Journal Title
  
  Nature 444
  
  Pages: 1069-1072
- Data Source
  KAKENHI-PROJECT-17023027
[Journal Article] Effects of perfluorooctane sulfate on action potentials and currents in cultured rat cerebellar Purkinje cells2006
- Author(s)
  Harada KH, Ishii TM, Takatsuka K, Koizumi A, Ohmori H
- Journal Title
  
  BBRC 351.1
  
  Pages: 240-245
- Data Source
  KAKENHI-PROJECT-17023027
[Journal Article] Axonal site of spike initiation enhances auditory coincidence detection.2006
- Author(s)
  Kuba, H.Ishii, M.T., Ohmori, H
- Journal Title
  
  Nature 444
  
  Pages: 1069-1072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17023027
[Journal Article] Hyperpolarization-Activated Cyclic Nucleotide-Gated Cation Channels Regulate Auditory Coincidence Detection in Nucleus Laminaris of the Chick2005
- Author(s)
  Rei Yamada, Hiroshi Kuba, Takahiro M.Ishii, Harunori Ohmori
- Journal Title
  
  J. Neuroscience 25
  
  Pages: 8867-8877
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590185
[Journal Article] Hyperpolarization-activated cyclicnucleotide gated cation channels regulate auditory coincidence detection in nucleus laminaris of the chick.2005
- Author(s)
  Rei Yamada, Hiroshi Kuba, Takahiro M. Ishii, Harunori Ohmori
- Journal Title
  
  Journal of Neuroscience 25
  
  Pages: 8867-8877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17023027
[Journal Article] A novel Ca2+ indicator protein using FRET and calpain-sensitive2005
- Author(s)
  Kenji Takatsuka, Takahiro M.Ishii, Harunori Ohmori
- Journal Title
  
  Biochemical and Biophysical Research Communications 336
  
  Pages: 316-323
- Data Source
  KAKENHI-PROJECT-17023027
[Journal Article] Hyperpolarization-activated cyclic-nucleotide gated cation channels regulate auditory coincidence detection in nucleus laminaris of the chick2005
- Author(s)
  Rei Yamada, Hiroshi Kuba, Takahiro M.Ishii, Harunori Ohmori
- Journal Title
  
  Journal of Neuroscience 25.39
  
  Pages: 8867-8877
- Data Source
  KAKENHI-PROJECT-17023027
[Journal Article] A novel Ca2+ indicator protein using FRET and calpain-sensitive linker2005
- Author(s)
  Kenji Takatsuka, Takahiro M.Ishii, Harunori Ohmori
- Journal Title
  
  Biochem.Biophys.Res.Comm. 336
  
  Pages: 316-323
- Data Source
  KAKENHI-PROJECT-15590185
[Journal Article] A novel Ca2+ indicator protein using FRET and calpain-sensitive linker2005
- Author(s)
  Kenji Takatsuka, Takahiro M. Ishii, Harunori Ohmori
- Journal Title
  
  Biochem.Biophys.Res.Comm. 336
  
  Pages: 316-323
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590185
[Journal Article] A novel Ca^<2+>indicator protein using FRET and calpain-sensitive linker2005
- Author(s)
  Kenji Takatsuka, Takahiro M.Ishii, Harunori Ohmori
- Journal Title
  
  Biochem. Biophys. Res. Comm. 336
  
  Pages: 316-323
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590185
[Journal Article] Hyperpolarization-Activated Cyclic Nucleotide-Gated Cation Channels Regulate Auditory Coincidence Detection in Nucleus Laminaris of the Chick2005
- Author(s)
  Rei Yamada, Hiroshi Kuba, Takahiro M.Ishii, Harunori Ohmori
- Journal Title
  
  J.Neuroscience 25
  
  Pages: 8867-8877
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590185
[Journal Article] Molecular Determinants of Deactivation Kinetics in Hyperpolarization-Activated Cation Channels2004
- Author(s)
  Ishii, Takahiro, Takano, Makoto, Ohmori, Harunori
- Journal Title
  
  The Japanese Journal of Physiology 54(Suppl.)
- NAID
  130005446947
- Data Source
  KAKENHI-PROJECT-15590185
[Journal Article] Roles of hyperpolarization-activated cation channels as a regulator of the EPSP time course in nucleus laminaris of the chick2004
- Author(s)
  Yamada, Rei, Kuba, Hiroshi, Ishii, Takahiro, Ohmori, Harunori
- Journal Title
  
  The Japanese Journal of Physiology 54(Suppl.)
- NAID
  130005447034
- Data Source
  KAKENHI-PROJECT-15590185
[Journal Article] Helical Structure of Si in the Hyperpolarization-Activated Cation Channel2004
- Author(s)
  Takahiro Ishii, Harunori Ohmori
- Journal Title
  
  Neuroscience Research 50 Suppl.1
- Data Source
  KAKENHI-PROJECT-15590185
[Journal Article] Halothane Inhibits an Intermediate Conductance Ca^<2+>-activated K+ Channel by Acting at the Extracellular Side of Ionic Pore2003
- Author(s)
  Mitsuko Hashiguchi-Ikeda, Tsunehisa Namba, Takahiro M.Ishii, Taizo Hisano, Kazuhirko Fukuda
- Journal Title
  
  Anesthesiology 99
  
  Pages: 1340-5
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590185
[Journal Article] 「研究成果報告書概要(欧文)」より2003
- Author(s)
  Mitsuko Hashiguchi-Ikeda, Tsunehisa Namba, Takahiro M.Ishii, Taizo Hisano, Kazuhiko Fukuda
- Journal Title
  
  Anesthesiology 99
  
  Pages: 1340-1345
- Data Source
  KAKENHI-PROJECT-15590185
[Patent] polypeptide having intracellular calcium ion indicator function2006
- Inventor(s)
  Ohmori H, Ishii T, Takatsuka K
- Industrial Property Rights Holder
  Kyoto University
- Filing Date
  2006-05-09
- Acquisition Date
  2010-01-12
- Overseas
- Data Source
  KAKENHI-PROJECT-17023027
[Patent] 細胞内カルシウムイオン指示機能を有するポリペプチド2005
- Inventor(s)
  大森治紀, 石井孝広, 高塚賢二
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2005-238034
- Filing Date
  2005-08-18
- Data Source
  KAKENHI-PROJECT-17023027
[Patent] 細胞内カルシウムイオン指示機能を有するポリペプチド2005
- Inventor(s)
  大森治紀、石井孝広、高塚賢二
- Industrial Property Rights Holder
  京都大学
- Filing Date
  2005-08-18
- Acquisition Date
  2007-03-01
- Data Source
  KAKENHI-PROJECT-17023027
[Presentation] アドレナリンβ2受容体の基底活性は、HCNチャネルを介してマウス嗅細胞の自発発火活動を維持する2012
- Author(s)
  中島則行、石井孝広、大森治紀
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-21590232
[Presentation] ラットモデルを用いた本態性振戦の遺伝要因の解明2011
- Author(s)
  庫本高志、大野行弘、今奥琢士、笹征史、石井孝広、芹川忠夫
- Organizer
  第34回神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590232
[Presentation] HCNチャネルは、マウス嗅細胞の自発発火活動を維持する2011
- Author(s)
  中島則行、石井孝広、大森治紀
- Organizer
  第34回神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590232
[Presentation] マウス嗅神経の自発発火におけるHCNチャネルの役割2010
- Author(s)
  中島則行、石井孝広、大森治紀
- Organizer
  第87回日本生理学会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-21590232
[Presentation] INTERACTION BETWEEN S1AND S4 IN THE VOLTAGE SENSOR OF HCNCHANNELS2009
- Author(s)
  Takahiro Ishii, Noriyuki Nakashima, and Harunori Ohmori
- Organizer
  The 36th Congress of the International Union of Physiological Sciences
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21590232
[Presentation] INTERACTION BETWEEN S1 AND S4 IN THE VOLTAGE SENSOR OF HCN CHANNELS2009
- Author(s)
  Takahiro Ishii, Noriyuki Nakashima, Harunori Ohmori
- Organizer
  The 36th Congress of the International Union of Physiological Sciences
- Place of Presentation
  Kyoto
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-21590232
[Presentation] HCNチャネルにおける電位センサーの機能と構造の関係2008
- Author(s)
  石井孝広、中島則行、大森治紀
- Organizer
  第85回日本生理学会大会
- Place of Presentation
  東京
- Year and Date
  2008-03-25
- Data Source
  KAKENHI-PROJECT-19590208
[Presentation] HCNチャネルの電位センサー領域の構造と機能に関する研究2008
- Author(s)
  石井孝広、中島則行、大森治紀
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590208
[Presentation] Structure-function relationship of voltage sensor in HCN channels2008
- Author(s)
  Takahiro Ishii, Noriyuki Nakashima, and Harunori Ohmori
- Organizer
  第85回日本生理学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590208
[Presentation] HCNチャネルの電位センサー領域の構造と機能に関する研究2008
- Author(s)
  石井孝広, 中島則行, 大森治紀
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590208

1. OHMORI Harunori (30126015)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. NAMBA Tsunehisa (30283609)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 古谷野好 (50183041)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KUBA Hirosi (10362469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 鷹野誠 (30236252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

ISHII Takahiro 石井 孝広

Research Projects

Research Products

Co-Researchers

Structure-function studies of voltage-sensors and cAMP-dependent activation in HCN channelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies of voltage sensor and ion permeability in HCN channelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Auditory Feature Extraction and Processing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

表面プラズモン共鳴を利用した揮発性麻酔薬とタンパク質との特異的結合定数の測定

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on physiological significance of hyperpolarization-activated cation channelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

過分極で活性化される陽イオンチャネルの構造と機能に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Action and mechanism of general anesthtics on subtypes of K channels

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

聴神経核における特徴抽出回路の形成と機能

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ニワトリ聴覚伝導路における特徴抽出機構の電気生理学的及び分子生物学的解析Principal Investigator

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[Journal Article] Controlled Release of Matrix Metalloproteinase-1 Plasmid DNA Prevents Left Ventricular Remodeling in Chronic Myocardial Infarction of Rats2011

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[Journal Article] Controlled Release of Matrix Metalloproteinase-1 Plasmid DNA Prevents Left Ventricular Remodeling in Chronic Myocardial Infarction of Rats2009

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[Journal Article] Tryptophan scanning mutagenesis in the S1 domain of mammalian HCN channel reveals residues critical for voltage-gated activation2007

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[Journal Article] Misexpression of Sox9 in mouse limb bud mesenchyme induces polydactyly and rescues hypodactyly mice2007

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[Journal Article] Peripheral N- and C-terminal domains determine deactivation kinetics of HCN channels2007

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[Journal Article] HCN and Cav3 ion Channels Confer Automaticity of Embryonic Stem Cell-derived Cardiomyocytes"2007

ISHII Takahiro 石井孝広