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hamabata takashi  濱端 崇

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… Alternative Names

濱端 崇  ハマバタ タカシ

Hamabata Takashi  濱端 崇

HAMABATA Takashi  浜端 崇

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Researcher Number 40311427
Affiliation (Current) 2025: 国立健康危機管理研究機構, 国立国際医療研究所, 室長
Affiliation (based on the past Project Information) *help 2020 – 2023: 国立研究開発法人国立国際医療研究センター, その他部局等, 細菌感染研究室長
2016: 国立研究開発法人国立国際医療研究センター, その他部局等, 細菌感染研究室長
2016: 国立研究開発法人国立国際医療研究センター, 感染症制御研究部, 細菌感染研究室長
2015: 国立研究開発法人国立国際医療研究センター, その他部局等, その他
2015: 国立研究開発法人国立国際医療研究センター, 感染症制御部, 細菌感染研究室長 … More
2014: 独立行政法人国立国際医療研究センター, その他部局等, 室長
2014: 独立行政法人国立国際医療研究センター, 感染症制御研究部, 室長
2004 – 2006: 国立国際医療センター研究所, 感染症制御研究部, 室長
2005: International Medical Center of Japan, Research Institute, Department of Infevtions Diseases, 感染症制御研究部, 室長
2000: Research Institute, International Medical Center of Japan, Division Director, 感染・熱帯病研究部, 室長
1999: 国立国際医療センター研究所, 室長
1998: 国立国際医療センター, 研究所, 室長
1996: International Medical Center of Japan, Research Institute, Division Chief, 研究所, 室長 Less
Review Section/Research Field
Principal Investigator
Basic Section 49050:Bacteriology-related / Bacteriology (including Mycology) / Bacteriology (including mycology)
Except Principal Investigator
Bacteriology (including Mycology) / Basic Section 49050:Bacteriology-related / Bacteriology (including Mycology) / Bacteriology (including mycology)
Keywords
Principal Investigator
O157:H7 / VBNC / カタラーゼ / コレラ菌 / ジフテリア菌 / 培養可能 / ウルセランス菌 / mouse infection model / infectious disease / vaccine … More / enteropaemorrhagic E.coli / マウス感染実験 / 感染症 / ワクチン / 腸管出血性大腸菌 / 培養可能状態 / RNAマイクロアレイ … More
Except Principal Investigator
腸管出血性大腸菌 / 病原性 / Gb3 / Enterohemorrhagic Escherichia coli / VT2vp1 / Aquaporin / NO還元酵素 / NO消去酵素 / 一酸化窒素(NO) / EHEC / 一酸化窒素 / O157 / プラスミド / NO抵抗性 / 生体防御機構抵抗因子 / Bacterial infection / Virulence / Secretion / Shiga toxins / 細菌感染症 / 分泌 / 志賀様毒素 / Vero toxin / Protective efficacy / Porcine edema disease / Vaccine strain / Non-toxic mutant / 無毒変異要素 / 無毒変異毒素 / 幼弱ブタ / 幼弱ウサギ / VT2 / 生菌ワクチン / Stx2 / ベロ毒素 / 感染防御能 / 豚浮腫病 / ワクチン株 / 無毒変異株 / IL-8 induction / O157 antigen synthesisi gene / Shiga toxin gene / cholera enterotoxin / enterohemorrhagic E.coli / Shigella dysenteriae / Vibrio cholerae / O抗原 / O22コレラ菌 / O139コレラ菌 / IL-8誘導 / O157抗原合成遺伝子 / 志賀毒素遺伝子 / 赤痢菌 / コレラ菌 / 水チャネル分子 / 下痢発症機構 / 腸管感染症菌 / cAMP / 水透過性 / 小腸上皮 / コレラ毒素 / 水チャネル / AQP / 薬剤耐性 / 嫌気性 / 動物実験 / 宿主防御機構 / 嫌気条件 / 抗菌薬 / 増殖性 / 活性酸素種 / 嫌気状態 / 志賀毒素 Less
  • Research Projects

    (8 results)
  • Research Products

    (10 results)
  • Co-Researchers

    (6 People)
  •  Research on the conversion mechanism from VBNC to culturable in pathogenic bacteriaPrincipal Investigator

    • Principal Investigator
      濱端 崇
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49050:Bacteriology-related
    • Research Institution
      National Center for Global Health and Medicine
  •  Identification and functional analysis of resistance factors for enterohemorrhagic Escherichia coli-specific defense mechanisms

    • Principal Investigator
      Shimizu Takeshi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49050:Bacteriology-related
    • Research Institution
      Chiba University
  •  Study on the conversion from VBNC to culturable state in Vibrio choleraePrincipal Investigator

    • Principal Investigator
      Hamabata Takashi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including mycology)
    • Research Institution
      National Center for Global Health and Medicine
  •  Establishment of absolute anaerobic biology for pathogenic evaluation of EHEC

    • Principal Investigator
      Shimizu Takeshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Bacteriology (including mycology)
    • Research Institution
      Chiba University
  •  Study on the virulence factors of enterohemorrhagic Escherichia coli

    • Principal Investigator
      SHIMIZU Takeshi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Chiba University
      University of Tsukuba
  •  Development of live oral vaccine of enterohaemorrhagic Escherichia coli O157:H7Principal Investigator

    • Principal Investigator
      HAMABATA Takashi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Research Institute, International Medical Center of Japan
  •  Development of a vaccine against enterohemorrhagic Escherichia coli

    • Principal Investigator
      TAKEDA Yoshifumi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      National Institute of Infections Diseases
      Research Institute, International Medical Center of Japan
  •  Mechanism of development of diarrhea by enteric bacteria

    • Principal Investigator
      TAKEDA Yoshifumi
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Research Institute, International Medical Center of Japan

All 2023 2022 2021 2015

All Journal Article Presentation

  • [Journal Article] Gene expression analysis during the conversion from a viable but nonculturable to culturable state in Vibrio cholerae2023

    • Author(s)
      Ayibieke Alafate、Nishiyama Ayae、Senoh Mitsutoshi、Hamabata Takashi
    • Journal Title

      Gene

      Volume: 863 Pages: 147289-147289

    • DOI

      10.1016/j.gene.2023.147289

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07064, KAKENHI-PROJECT-22K15466
  • [Journal Article] Enhanced production of Shiga toxin 1 in enterohaemorrhagic Escherichia coli by oxygen2021

    • Author(s)
      Shimizu Takeshi、Onuki Manami、Suzuki Shin、Hirai Shinichiro、Yokoyama Eiji、Matsumoto Akio、Hamabata Takashi
    • Journal Title

      Microbiology

      Volume: 167 Issue: 12 Pages: 1-11

    • DOI

      10.1099/mic.0.001122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07474
  • [Journal Article] A factor converting viable but nonculturable Vibrio cholerae to a culturable state in eukaryotic cells is a human catalase2015

    • Author(s)
      Senoh M, Hamabata T, Takeda Y
    • Journal Title

      MicrobiologyOpen

      Volume: 4 Issue: 4 Pages: 589-596

    • DOI

      10.1002/mbo3.264

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460543
  • [Presentation] Enhanced resistance of enterohemorrhagic Escherichia coli to bactericidal substances by plasmid factor2023

    • Author(s)
      Takeshi Shimizu, Shin Suzuki and Takashi Hamabata
    • Organizer
      第96回 日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-20K07474
  • [Presentation] Gene expression analysis during the conversion from a VBNC to culturable state in Vibrio cholerae2023

    • Author(s)
      Alafate Ayibieke、西山紋惠、妹尾充敏、濱端崇
    • Organizer
      第57回日米医学協力委員会コレラ・細菌性腸管感染症部会日米合同会議
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07064
  • [Presentation] Gene expression analysis during the conversion from a VBNC to culturable state in Vibrio cholerae2023

    • Author(s)
      Alafate Ayibieke, 西山紋恵, 妹尾充敏, 濱端崇
    • Organizer
      第96回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-22K07064
  • [Presentation] 腸管出血性大腸菌のプラスミド因子による生態殺菌物質に対する抵抗性の増強2023

    • Author(s)
      清水健, 鈴木眞, 濱端崇
    • Organizer
      第96回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-22K07064
  • [Presentation] Enhanced production of Shiga toxin 2 in enterohemorrhagic Escherichia coli by oxygen2022

    • Author(s)
      Takeshi Shimizu, Manami Onuki, Shinichiro Hirai, Eiji Yokoyama, Akio Matsumoto and Takashi Hamabata
    • Organizer
      第95回 日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-20K07474
  • [Presentation] 腸管出血性大腸菌のプラスミド因子による生体殺菌物質に対する抵抗性の増強2022

    • Author(s)
      清水 健、鈴木 眞、濱端 崇
    • Organizer
      第24回腸管出血性大腸菌感染症研究会
    • Data Source
      KAKENHI-PROJECT-20K07474
  • [Presentation] 腸管出血性大腸菌の志賀毒素産生における酸素の影響2021

    • Author(s)
      清水 健、大貫真奈美、松本明郎、濱端 崇
    • Organizer
      第94回 日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-20K07474
  • 1.  Shimizu Takeshi (70312840)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 2.  Senoh Mitsutoshi (20646624)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 3.  TAKEDA Yoshifumi (30029772)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  YAMASAKI Shinji (70221653)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  MAKINO Sou-ichi (30181621)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  野田 公俊 (60164703)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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