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YOSHIZAWA TATSUYA  吉澤 達也

… Alternative Names

YOSHIZAWA Tatsuya  吉澤 達也

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Researcher Number 40313530
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-5728-1996
Affiliation (Current) 2022: 熊本大学, 大学院生命科学研究部(医), 准教授
Affiliation (based on the past Project Information) *help 2015 – 2022: 熊本大学, 大学院生命科学研究部(医), 准教授
2014 – 2015: 熊本大学, 大学院生命科学研究部, 准教授
2014: 熊本大学, 生命科学研究科, 准教授
2013: 熊本大学, 生命科学研究部, 講師
2011 – 2013: 熊本大学, 大学院生命科学研究部, 講師 … More
2007: 新潟大, 医歯学系, 助手
2005 – 2006: 新潟大学, 医歯学系, 助手
2001 – 2004: Graduate School of Medical and Dental Sciences, Niigata University, Assistant, 大学院・医歯学総合研究科, 助手
1999 – 2000: Faculty of Dentistry, Niigata University Assistant, 歯学部, 助手 Less
Review Section/Research Field
Principal Investigator
Functional basic dentistry / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Functional basic dentistry / Metabolomics / Pathological medical chemistry / Orthopaedic surgery / Biological Sciences / Basic Section 59040:Nutrition science and health science-related
Except Principal Investigator
Functional basic dentistry / Metabolomics … More / Social dentistry / Basic Section 54040:Metabolism and endocrinology-related / Prosthetic dentistry / Functional basic dentistry / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Basic Section 57050:Prosthodontics-related Less
Keywords
Principal Investigator
サーチュイン / 骨芽細胞 / アシル化 / 石灰化 / 細胞分化 / 歯根膜 / 靭帯 / シグナル伝達 / 骨 / インスリン … More / 糖代謝 / 腸管 / 骨組織 / 運動器 / 骨格筋 / 歯根膜細胞 / セメント芽細胞 / 硬組織 / 細胞生物学 / 分子生物学 / 後縦靭帯骨化症 / Runx2 / Msx2 / 靱帯 / 後縦靱帯骨化症 / 細胞・組織 / 機械的刺激 / 糖尿病 / インスリン受容体 / 骨粗鬆症 / SIRT7 / 老化 / ロコモティブシンドローム / Osterix / 骨代謝 / 間葉系幹細胞 / 幹細胞 / タンパク質翻訳後修飾 / 神経幹細胞 / 脂肪酸アシル化 / アシル化修飾 / ホルモン / 臓器連関 / グルココルチコイド / グルココルチコイドレセプター … More
Except Principal Investigator
メカニカルストレス / サーチュイン / SIRT7 / 糖尿病 / 骨芽細胞 / 骨芽細胞分化 / 破骨細胞 / 骨形成 / 遺伝子発現 / α-adaptin C / OPLL / Msx2 / 脂肪細胞 / 転写因子 / インスリン / 骨代謝 / スフィンゴミエリン合成酵素 / Mechanical stress / BMP-4 / Osteoblast differentiation / Osteogenesis / PIASxβ / 骨 / 褐色脂肪細胞 / 褐色脂肪組織 / ヒアルロン酸 / インスリン分泌 / MODY / HNF / グルコキナーゼ / 破骨細胞分化因子 / 糖代謝 / in situ hybridization / 遺伝子クローニング / osteogenesis / osteoblast differentiation / gene cloning / クローニング / α-adaptinC / sIL-1RAcP / 網羅的遺伝子クローニング / Tensile stress / BMP - 4 / Tetranectin / 歯根膜細胞 / 石灰化 / エンドサイトーシス / 歯芽細胞 / Periodontal ligament / Mineralization / 靭帯細胞 / 石灰化抑制機構 / インテグリン / Osterix / PIASXβ / mechanical stress / ligament cells / osteoblasts / mechanism of mineralization / integrins / osterix / スフィンゴ脂質 / スフィンゴミエリン / 細胞膜 / 細胞・組織 / 脂肪肝 / SIRT7 / 肝臓 / TR4 / ユビキチンリガーゼ複合体 / 褐色脂肪 / DDB1 / サーチュン / エネルギー代謝 / PPARγ / PPARg / PPARgamma / アセチル化 / アシル化 / アシル化修飾 / 炎症 / シクロデキストリン Less
  • Research Projects

    (24 results)
  • Research Products

    (58 results)
  • Co-Researchers

    (45 People)
  •  Regulation of glucose metabolism by SIRT7

    • Principal Investigator
      山縣 和也
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Kumamoto University
  •  グルココルチコイド作用を分ける新規転写制御機構の解明および副作用軽減法の開発Principal Investigator

    • Principal Investigator
      吉澤 達也
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
    • Research Institution
      Kumamoto University
  •  骨結合性超分子による破骨細胞機能調節 -骨吸収抑制新規治療薬の開発-

    • Principal Investigator
      吉川 美弘
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57050:Prosthodontics-related
    • Research Institution
      Osaka Dental University
  •  New roles of bone tissue in the maintenance of homeostasis.Principal Investigator

    • Principal Investigator
      Yoshizawa Tatsuya
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
    • Research Institution
      Kumamoto University
  •  中鎖脂肪酸修飾タンパク質による新たな運動器恒常性維持機構の解明Principal Investigator

    • Principal Investigator
      吉澤 達也
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Kumamoto University
  •  Molecular mechanism of metabolic regulation through protein acylations

    • Principal Investigator
      Yamagata Kazuya
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
    • Research Institution
      Kumamoto University
  •  Identification of the metabolic roles of SIRT7 and the development of its regulation.

    • Principal Investigator
      Yamagata Kazuya
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Kumamoto University
  •  中長鎖脂肪酸アシル化修飾タンパク質による運動器を基軸とした代謝調節機構の解明Principal Investigator

    • Principal Investigator
      吉澤 達也
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      Kumamoto University
  •  Elucidation of egulatory mechanism of bone metabolism by lysine deacylase SIRT7.Principal Investigator

    • Principal Investigator
      Yoshizawa Tatsuya
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kumamoto University
  •  Study of the mechanism of sphingolipids on bone metabolism

    • Principal Investigator
      YOSHIKAWA YOSHIHIRO
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Social dentistry
    • Research Institution
      Osaka Dental University
  •  タンパク質リジンアシル化修飾の調節による幹細胞システムの制御とその加齢変化Principal Investigator

    • Principal Investigator
      吉澤 達也
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  Identification of the multifaceted metabolic roles of SIRT7

    • Principal Investigator
      Yamagata Kazuya
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Kumamoto University
  •  The new function of insulin in gut.Principal Investigator

    • Principal Investigator
      Yoshizawa Tatsuya
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kumamoto University
  •  Sphingomyelin regulates blood glucose levels by bone tissue

    • Principal Investigator
      YOSHIKAWA Yoshihiro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Social dentistry
    • Research Institution
      Osaka Dental University
  •  Molecular mechanism of diabetes mellitus based on beta-cell transcription factor network

    • Principal Investigator
      Yamagata Kazuya
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Kumamoto University
  •  Study of the new insulin action in the peripheral tissuesPrincipal Investigator

    • Principal Investigator
      YOSHIZAWA TATSUYA
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kumamoto University
  •  The availability of elderly-friendly macromolecule polysaccharide in periodontal tissue.

    • Principal Investigator
      KAWAMOTO Akiyo
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Prosthetic dentistry
    • Research Institution
      Osaka Dental University
  •  石灰化促進・抑制機構を骨芽細胞と靭帯線維芽細胞を用いて探るPrincipal Investigator

    • Principal Investigator
      吉澤 達也
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Niigata University
  •  Cell-specific response to mechanical stress and regulatory mechanism of differentiation : ligament/tendon cells versus osteoblasts

    • Principal Investigator
      KAWASHIMA Hiroyuki
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Niigata University
  •  歯根膜細胞の特性と分化制御機構の解析Principal Investigator

    • Principal Investigator
      吉澤 達也
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Niigata University
  •  Molecular mechanism of osteogenesis-induced osteogenesis

    • Principal Investigator
      KAWASHIMA Hiroyuki
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Niigata University
  •  歯根膜細胞から硬組織形成系細胞への分化制御機構の解析Principal Investigator

    • Principal Investigator
      吉澤 達也
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Niigata University
  •  On the analysis and regulatory mechanism of genes responsible for mechanical stress-induced osteoblast differentiation and osteogenesis

    • Principal Investigator
      KAWASHIMA Hiroyuki
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Niigata University
  •  Mechanism of mechanical stress-induced osteoblast differentiation and osteogenesis

    • Principal Investigator
      KAWASHIMA Hiroyuki
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Niigata University

All 2021 2020 2019 2018 2017 2016 2015 2014 2004 Other

All Journal Article Presentation

  • [Journal Article] SIRT7 regulates lipogenesis in adipocytes through deacetylation of PPARg2.2021

    • Author(s)
      Akter F, Tsuyama T, Yoshizawa T, Sobuz SU, Yamagata K
    • Journal Title

      J Diabetes Invest

      Volume: Unknown

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K22639
  • [Journal Article] Sirt7 deficiency attenuates neointimal formation following vascular injury by modulating vascular smooth muscle cells proliferation.2021

    • Author(s)
      Kimura Y, Izumiya Y, Araki S, Yamamura S, Hanatani S, Onoue Y, Ishida T, Arima Y, Nakamura T, Bober E, Braun T, Kaikita K, Yamagata K, Tsujita K
    • Journal Title

      Circulation Journal

      Volume: 85 Issue: 12 Pages: 2232-2240

    • DOI

      10.1253/circj.cj-20-0936

      10.1253/circj.CJ-20-0936

    • NAID

      130008119968

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15852, KAKENHI-PROJECT-19H03654, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-16H06276
  • [Journal Article] SIRT7 regulates lipogenesis in adipocytes through deacetylation of PPARg2.2021

    • Author(s)
      Akter F, Tsuyama T, Yoshizawa T, Sobuz SU, Yamagata K
    • Journal Title

      J Diabetes Investig

      Volume: 10 Pages: 1765-1774

    • DOI

      10.1111/jdi.13567

    • Description
      in press
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-20H04107, KAKENHI-PROJECT-16H06276
  • [Journal Article] SIRT7 regulates lipogenesis in adipocytes through deacetylation of PPARg2.2021

    • Author(s)
      Akter F, Tsuyama T, Yoshizawa T, Sobuz SU, Yamagata K
    • Journal Title

      J Diabetes Invest

      Volume: Unknown

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03711
  • [Journal Article] Cardiomyocyte Sirt (Sirt7)7 ameliorates stress-induced cardiac hypertrophy by interacting with and deacetylating GATA42020

    • Author(s)
      Yamamura S, Izumiya Y, Araki S, Nakagata N, Bober E, Braun T, Sakamoto K, Kaikita K, Morimoto T, Yamagata K, Tsujita K
    • Journal Title

      Hypertension

      Volume: 75 Pages: 98-108

    • DOI

      10.1161/hypertensionaha.119.13357

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08110, KAKENHI-PROJECT-19K22639, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-17K08279, KAKENHI-PROJECT-16H06276
  • [Journal Article] HNFla controls glucagon secretion in pancreatic a-cells through modulation of SGLT12020

    • Author(s)
      Sato Y, Rahman MM, Haneda M, Tsuyama T, Mizumoto T, Yoshizawa T, Kitamura T, Gonzalez FJ, Yamamura K, Yamagata K
    • Journal Title

      BBA - Mol Basis Dis

      Volume: 1866 Pages: 165898-165898

    • DOI

      10.1016/j.bbadis.2020.165898

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09008, KAKENHI-PROJECT-20K17538, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-19K22639, KAKENHI-PROJECT-16H06276
  • [Journal Article] Brown adipocyte-derived miR-132-3p suppress hepatic Srebfl expression and thereby attenuate expression of lipogenic genes2020

    • Author(s)
      Kariba Y, Yoshizawa T, Sato Y, Tsuyama T, Araki E, Yamagata K
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 530 Pages: 500-507

    • DOI

      10.1016/j.bbrc.2020.05.090

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09008, KAKENHI-PROJECT-20K17538, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-18K08482, KAKENHI-PROJECT-19K22639, KAKENHI-PROJECT-16H06276
  • [Journal Article] Knockdown of sphingomyelin synthase 2 inhibits osteoclastogenesis by decreasing RANKL expression in mouse primary osteoblasts2019

    • Author(s)
      YOSHIKAWA Yoshihiro、YOSHIZAWA Tatsuya、DOMAE Eisuke、HIRAI Yuya、KAMADA Aiko、OKAZAKI Toshiro、IKEO Takashi
    • Journal Title

      Biomedical Research

      Volume: 40 Issue: 5 Pages: 189-196

    • DOI

      10.2220/biomedres.40.189

    • NAID

      130007724777

    • ISSN
      0388-6107, 1880-313X
    • Language
      English
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K12068
  • [Journal Article] SIRT7 regulates the nuclear export of NF-kB p65 by deacetylating Ran.2019

    • Author(s)
      Sobuz SU, Sato Y, Yoshizawa T, Karim MF, Ono K, Sawa T, Miyamoto Y, Oka Y, Yamagata K
    • Journal Title

      BBA-Mol Cell Res

      Volume: 1866 Pages: 1355-1367

    • DOI

      10.1016/j.bbamcr.2019.05.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09008, KAKENHI-PROJECT-19K22639, KAKENHI-PROJECT-17H03679, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-16H06276
  • [Journal Article] Angiopoietin-like protein 2 promotes chondrogenic differentiation during bone growth as a cartilage matrix factor.2018

    • Author(s)
      Tanoue H, Morinaga J, Yoshizawa T, Yugami M, Itoh H, Nakamura T, Uehara Y, Masuda T, Odagiri H, Sugizaki T, Kadomatsu T, Miyata K, Endo M, Terada K, Ochi H, Takeda S, Yamagata K, Fukuda T, Mizuta H, Oike Y.
    • Journal Title

      Osteoarthr Cartilage

      Volume: 26 Pages: 108-117

    • DOI

      10.1016/j.joca.2017.10.011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08663, KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-15K06836
  • [Journal Article] Age-dependent increase in angiopoietin-like protein 2 accelerates skeletal muscle loss in mice2018

    • Author(s)
      Zhao J, Tian Z, Kadomatsu T, Xie P, Miyata K, Sugizaki T, Endo M, Zhu S, Fan H, Horiguchi H, Morinaga J, Terada K, Yoshizawa T, Yamagata K, Oike Y.
    • Journal Title

      J Biol Chem.

      Volume: 293 Pages: 1596-1609

    • DOI

      10.1074/jbc.m117.814996

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08663, KAKENHI-PUBLICLY-17H05652, KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-17F17121, KAKENHI-PROJECT-16K09504, KAKENHI-PROJECT-15K06836, KAKENHI-PROJECT-16K15445, KAKENHI-PROJECT-18K19519
  • [Journal Article] Sirtuin 7 is involved in the consolidation of fear memory in mice2018

    • Author(s)
      Islam Md Safiqul、Wei Fan-Yan、Ohta Kunimasa、Shigematsu Naoki、Fukuda Takaichi、Tomizawa Kazuhito、Yoshizawa Tatsuya、Yamagata Kazuya
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 495 Pages: 261-266

    • DOI

      10.1016/j.bbrc.2017.10.159

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-17H05650, KAKENHI-PROJECT-16H05328
  • [Journal Article] Sirtuin 7 deficiency ameliorates cisplatin-induced acute kidney injury through regulation of the inflammatory response.2018

    • Author(s)
      Miyasato Y, Yoshizawa T, et al.
    • Journal Title

      Sci. Rep

      Volume: 8 Pages: 5927-5927

    • DOI

      10.1038/s41598-018-24257-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09268, KAKENHI-PROJECT-26461234, KAKENHI-PROJECT-17K09705, KAKENHI-PROJECT-17K09706, KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-16K09758, KAKENHI-PROJECT-16H06276
  • [Journal Article] SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix2018

    • Author(s)
      Fukuda M, Yoshizawa T, et al.
    • Journal Title

      Nat Commun

      Volume: 9 Pages: 1-14

    • DOI

      10.1038/s41467-018-05187-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06600, KAKENHI-PUBLICLY-17H05650, KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-17H04105, KAKENHI-PROJECT-15K11027, KAKENHI-PROJECT-16K09758, KAKENHI-PROJECT-17K11014, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H05440
  • [Journal Article] SIRT7 is an important regulator of cartilage homeostasis and osteoarthritis development2018

    • Author(s)
      Korogi W, Yoshizawa T, Karim MF, Tanoue H, Yugami M, Sobuz SU, Hinoi E, Sato Y, Oike Y, Mizuta H, Yamagata K
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 印刷中 Pages: 891-897

    • DOI

      10.1016/j.bbrc.2018.01.129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-16K09758
  • [Journal Article] Transcriptional regulation of metabolism by SIRT1 and SIRT72017

    • Author(s)
      Yamagata K, Yoshizawa T
    • Journal Title

      Int. Rev. Cel. Mol. Bio.

      Volume: 335 Pages: 143-166

    • DOI

      10.1016/bs.ircmb.2017.07.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05328
  • [Journal Article] SIRT7-dependent deacetylation of DDB1 regulates the expression of nuclear receptor TR42017

    • Author(s)
      Karim MF, Yoshizawa T, Sobuz SU, Sato Y, Yamagata K
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 490 Pages: 423-428

    • DOI

      10.1016/j.bbrc.2017.06.057

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05328
  • [Journal Article] Hypoxia reduces HNF4α/MODY1 protein expression in pancreatic β-cells by activating AMP-activated protein kinase2017

    • Author(s)
      Sato Y, Karim MF et al.
    • Journal Title

      J Biol. Chem.

      Volume: 印刷中 Pages: 8716-8728

    • DOI

      10.1074/jbc.m116.767574

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K21238, KAKENHI-PROJECT-16K09758, KAKENHI-PROJECT-16H05328
  • [Journal Article] RNA interference-mediated knockdown of Smad1 inhibits receptor activator of nuclear factor B ligand expression induced by BMP-2 in primary osteoblasts2015

    • Author(s)
      Yoshikawa Y, Yoshizawa T, Domae E, Hieda Y, Takeyama A, Hirota S, Kawamoto A, Goda S, Tamura I, Kamada A, Komasa Y, Morita S, Yamagata K, Ikeo T.
    • Journal Title

      Arch Oral Biol.

      Volume: 60 Pages: 1319-1326

    • DOI

      10.1016/j.archoralbio.2015.06.001

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26463202, KAKENHI-PROJECT-25293212
  • [Journal Article] SIRT7 controls hepatic lipid metabolism by regulating the ubiquitin- proteasome pathway.2014

    • Author(s)
      Yoshizawa T, Karim Md. F, Sato Y, Senokuchi T, Miyata K, Fukuda T, Go C, Tasaki M, Uchimura K, Kadomatsu T, Tian Z, Smolka C, Sawa T, Kakeya M, Tomizawa K, Ando Y, Araki E, Akaike T, Braun T, Oike Y, Bober E, Yamagata K.
    • Journal Title

      Cell metab

      Volume: 9 Pages: 712-21

    • DOI

      10.1016/j.cmet.2014.03.006

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-11F01105, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-24390082, KAKENHI-PROJECT-24790557, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25253020, KAKENHI-PROJECT-25293212, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461361, KAKENHI-PROJECT-25870543, KAKENHI-PLANNED-26111008, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26670207, KAKENHI-PROJECT-26670405, KAKENHI-PROJECT-26860697, KAKENHI-PROJECT-26861112
  • [Journal Article] Homeobox protein Msx2 acts as a molecular defense mechanism for preventing ossification in ligament fibroblasts.2004

    • Author(s)
      T.Yoshizawa et al.
    • Journal Title

      Molecular and Cellular Biology 24(8)

      Pages: 3460-3472

    • Data Source
      KAKENHI-PROJECT-15791056
  • [Journal Article] Homeobox protein Msx2 acts as a molecular-defense mechanism for preventing ossification in ligament fibroblasts2004

    • Author(s)
      吉澤 達也 他7名
    • Journal Title

      Mol.Cell.Biol. 24・8

      Pages: 3460-3472

    • Data Source
      KAKENHI-PROJECT-16390531
  • [Presentation] The diverse functions of NAD-dependent lysine deacylase SIRT7.2021

    • Author(s)
      Tatsuya Yoshizawa
    • Organizer
      KSBMB (Korean Society for Biochemistry and Molecular Biology) International Conference 2021 (Symposium)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H04107
  • [Presentation] HNF-1αによる膵α細胞機能制御メカニズムの解明2020

    • Author(s)
      佐藤叔史、Md Mostafizur Rahman、羽根田昌樹、水本智也、津山友徳、吉澤達也、北村忠弘、Frank J Gonzalez、山村研一、山縣和也
    • Organizer
      第63回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-19H03711
  • [Presentation] HNF-1αによる膵α細胞機能制御メカニズムの解明2020

    • Author(s)
      佐藤叔史、Md Mostafizur Rahman、羽根田昌樹、水本智也、津山友徳、吉澤達也、北村忠弘、Frank J Gonzalez、山村研一、山縣和也
    • Organizer
      第63回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-19K22639
  • [Presentation] 低酸素誘導性BHLHE40によるβ細胞機能低下機序の解明2019

    • Author(s)
      佐藤叔史、津山友徳、吉澤達也、松岡孝昭、山縣和也
    • Organizer
      第62回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-19K22639
  • [Presentation] 低酸素ストレスはBhlhe40-Mafa経路を介してインスリン分泌不全を誘導する2019

    • Author(s)
      津山友徳、佐藤叔史、吉澤達也、松岡孝昭、山縣和也
    • Organizer
      第42回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-19H03711
  • [Presentation] 脱アセチル化酵素SIRT7によるNF-kB p65の核外輸送制御メカニズムの解明2019

    • Author(s)
      佐藤叔史、Sobuz Shihab U.、吉澤達也、Fazlul Karim、小野勝彦、澤智裕、宮本洋一、岡正啓、山縣和也
    • Organizer
      第42回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-19K22639
  • [Presentation] 脱アセチル化酵素SIRT7によるNF-kB p65の核外輸送制御メカニズムの解明2019

    • Author(s)
      佐藤叔史、Sobuz Shihab U.、吉澤達也、Fazlul Karim、小野勝彦、澤智裕、宮本洋一、岡正啓、山縣和也
    • Organizer
      第42回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-19H03711
  • [Presentation] Role of NAD-dependent lysine deacylase in bone.2019

    • Author(s)
      吉澤達也
    • Organizer
      第16回 Bone Biology Forum
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04676
  • [Presentation] 低酸素ストレスはBhlhe40-Mafa経路を介してインスリン分泌不全を誘導する2019

    • Author(s)
      津山友徳、佐藤叔史、吉澤達也、松岡孝昭、山縣和也
    • Organizer
      第42回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-19K22639
  • [Presentation] 低酸素誘導性BHLHE40によるβ細胞機能低下機序の解明2019

    • Author(s)
      佐藤叔史、津山友徳、吉澤達也、松岡孝昭、山縣和也
    • Organizer
      第62回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-19H03711
  • [Presentation] サーチュインによる骨代謝制御2018

    • Author(s)
      吉澤達也
    • Organizer
      日本薬学会第138年会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-17H05650
  • [Presentation] SIRT7によるエネルギー代謝調節2018

    • Author(s)
      吉澤達也
    • Organizer
      日本筋学会第4回学術集会 シンポジウム
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04676
  • [Presentation] サーチュインによる骨代謝制御2018

    • Author(s)
      吉澤達也
    • Organizer
      日本薬学会第138年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K11014
  • [Presentation] 脱アシル化酵素SIRT7によるエネルギー代謝制御2018

    • Author(s)
      吉澤達也
    • Organizer
      第72回日本栄養・食糧学会大会 シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K11014
  • [Presentation] エクソソームを介した褐色脂肪組織から肝臓への新たな生理作用の解明2018

    • Author(s)
      狩場佑一、吉澤達也、山縣和也
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16H05328
  • [Presentation] 脱アシル化酵素SIRT7によるエネルギー代謝制御2018

    • Author(s)
      吉澤達也
    • Organizer
      第72回日本栄養・食糧学会大会 シンポジウム
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04676
  • [Presentation] Bhlhe40-Mafa経路を介した低酸素ストレスによるインスリン分泌抑制2018

    • Author(s)
      津山友徳、佐藤叔史、吉澤達也、松岡孝昭、山縣和也
    • Organizer
      第41回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-16H05328
  • [Presentation] 脱アシル化酵素SIRT7によるエネルギー代謝制御2018

    • Author(s)
      吉澤達也
    • Organizer
      第72回日本栄養・食糧学会大会 シンポジウム
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-17H05650
  • [Presentation] 膵β細胞低酸素によるHNF4蛋白低下メカニズムの解明2017

    • Author(s)
      佐藤叔史、津山友徳、佐藤ちなみ、Md. Fazlul Karim、吉澤達也、井上正宏、山縣和也
    • Organizer
      日本生化学学会九州支部例会
    • Data Source
      KAKENHI-PROJECT-16H05328
  • [Presentation] SIRT7による多様な代謝制御2017

    • Author(s)
      吉澤達也
    • Organizer
      ConBio2017 ワークショップ:核内受容体が制御する多彩な生命現象
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-17H05650
  • [Presentation] 脱アシル化酵素SIRT7によるOsterixの転写活性化は骨形成に重要である2017

    • Author(s)
      吉澤達也
    • Organizer
      第90回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PUBLICLY-17H05650
  • [Presentation] 脱アシル化酵素SIRT7によるOsterixの転写活性化は骨形成に重要である2017

    • Author(s)
      吉澤達也
    • Organizer
      第90回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K11014
  • [Presentation] 核内脱アシル化酵素SIRT7は軟骨細胞分化を制御し、変形性膝関節症の発症に関与する2017

    • Author(s)
      興梠 航、吉澤達也、山縣和也
    • Organizer
      第35回日本骨代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05328
  • [Presentation] 急性尿細管障害におけるSIRT7の機能解明2017

    • Author(s)
      宮里腎和、吉澤達也、中川輝政、柿添 豊、桒原孝成、安達政隆、向山政志、山縣和也
    • Organizer
      第21回日本心血管内分泌代謝学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H05328
  • [Presentation] SIRT7とアンチエイジング2017

    • Author(s)
      山縣和也、吉澤達也
    • Organizer
      脳心血管抗加齢研究会2017
    • Data Source
      KAKENHI-PROJECT-16H05328
  • [Presentation] SIRT7による多様な代謝制御2017

    • Author(s)
      吉澤達也
    • Organizer
      ConBio2017 ワークショップ:核内受容体が制御する多彩な生命現象
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K11014
  • [Presentation] SIRT7によるエネルギー代謝制御2017

    • Author(s)
      山縣和也、吉澤達也
    • Organizer
      第90回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H05328
  • [Presentation] 脱アシル化酵素SIRT7によるOsterixの転写活性化は骨形成に重要である2017

    • Author(s)
      吉澤達也、福田雅俊、竹田秀、山縣和也
    • Organizer
      第90回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H05328
  • [Presentation] SIRT7によるエネルギー代謝制御2016

    • Author(s)
      吉澤達也、山縣和也
    • Organizer
      第37回日本肥満学会
    • Data Source
      KAKENHI-PROJECT-16H05328
  • [Presentation] SIRT7による代謝制御作用2016

    • Author(s)
      山縣和也、吉澤達也
    • Organizer
      脳心血管抗加齢研究会2016
    • Data Source
      KAKENHI-PROJECT-16H05328
  • [Presentation] Deletion of Sirtuin 7 Ameliorates Cisplatin-Induced Acute Kidney Injury through Regulation of Inflammatory Response.2016

    • Author(s)
      Yoshikazu Miyasato, Tatsuya Yoshizawa, Terumasa Nakagawa, Yutaka Kakizoe, Yuichiro Izumi, Takashige Kuwabara, Masataka Adachi, Eva Bober, Masashi Mukoyama, Kazuya Yamagata
    • Organizer
      The American Society of Nephrology (ASN) Kidney Week 2016 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05328
  • [Presentation] ARNTはARNT/HIF-1αによる血管形成とは独立して直接骨芽細胞の分化を促進する2016

    • Author(s)
      福田雅俊、吉澤達也、池亀美華、竹田秀、山縣和也
    • Organizer
      第34回日本骨代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05328
  • [Presentation] 代謝制御におけるSIRT7の多様な役割2016

    • Author(s)
      吉澤達也、山縣和也
    • Organizer
      第89回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16H05328
  • [Presentation] 核内脱アセチル化酵素SIRT7はOsterixを介して骨形成を制御する2016

    • Author(s)
      吉澤達也、福田雅俊、興梠航、竹田秀、山縣和也
    • Organizer
      第34回日本骨代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05328
  • [Presentation] SIRT7による糖脂質代謝制御2015

    • Author(s)
      吉澤達也
    • Organizer
      第58回日本糖尿病学会年次学術集会
    • Place of Presentation
      山口市
    • Year and Date
      2015-05-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293212
  • [Presentation] Sirt7遺伝子欠損マウスは、高脂肪食負荷による糖尿病・脂肪肝・肥満に抵抗性である

    • Author(s)
      吉澤達也
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-05-22 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-25293212
  • 1.  Yamagata Kazuya (70324770)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 40 results
  • 2.  YOSHIKAWA Yoshihiro (70434793)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 3.  Sato Yoshifumi (90622598)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 16 results
  • 4.  KAWASHIMA Hiroyuki (40169719)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  ISHIBASHI Osamu (70293214)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  IKEGAME Mika (70282986)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  池尾 隆 (40159603)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 8.  MATSUDA Akio (10359705)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  岡崎 俊朗 (40233308)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 10.  KAWAMOTO Akiyo (50368156)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  OKAZAKI Joji (80169094)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  門松 毅 (90555757)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 13.  里方 一郎 (70170800)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  田村 篤志 (80631150)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  小野 悠介 (60601119)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  津山 友徳 (10845960)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 17.  Sawa Tomohiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 15 results
  • 18.  ENDO Motoyoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 19.  MORIMOTO Tatsuya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  LI Zhenghua
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  SENOKUCHI Takafumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  TIAN Zhe
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 23.  Inoue Masahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  Tasaki Masayoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 25.  NAKAMURA Hideo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  井本 正哉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  荒木 喜美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 28.  尾池 雄一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 29.  宮田 敬士
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 30.  赤池 孝章
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  荒木 正健
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  KARIM MD・FAZLUL
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  木村 優一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  佐田 政隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  中村 卓郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  桑原 孝成
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  柿添 豊
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  向山 政志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  荒木 栄一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  森岡 弘志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  小橋川 敬博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  佐藤 卓史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  中島 和久
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  荒木 令江
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 45.  岡 正啓
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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