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shimizu tatsuya  清水 達也

… Alternative Names

SHIMIZU Tatsuya  清水 達也

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Researcher Number 40318100
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-7601-4239
External Links
Affiliation (Current) 2025: 東京女子医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2015 – 2024: 東京女子医科大学, 医学部, 教授
2008: 東京女子医科大学, 医学部, 准教授
2003 – 2007: Tokyo Women's Medical University, Department of Medicine, Assistant Professor, 医学部, 講師
2006: Tokyo Women's Medical University, Department of Medicine, Assistant Professor, 医学部, 助教授
2001 – 2002: 東京女子医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Basic Section 90110:Biomedical engineering-related / Medium-sized Section 90:Biomedical engineering and related fields / Biomedical engineering/Biomaterial science and engineering / Biomedical engineering/Biological material science / Biomedical engineering/Biological material science
Except Principal Investigator
Biomedical engineering/Biological material science / Basic Section 90110:Biomedical engineering-related / Biomedical engineering/Biomaterial science and engineering / Science and Engineering / Neurophysiology and muscle physiology / Biomedical engineering/Biological material science / Thoracic surgery
Keywords
Principal Investigator
組織工学 / 細胞シート / 立体的組織 / 血管内皮網 / 立体組織 / 膵臓再生 / 血管床 / 灌流培養 / 温度変化 / 血管網 … More / 膵島β細胞 / 筋組織 / 筋細胞 / 光合成 / 藻類 / 3次元組織 / iPS細胞 / 生体外灌流培養 / ヒトiPS細胞 / 還流培養 / バイオメカニクス / 発生 / 灌流 / オルガノイド / 血流 / 気ー液界面 / 腎オルガノイド / 腎発生 / かん流培養 / 細胞・組織 / 生体材料 / 組織・細胞 / 再生医学 / 心筋細胞 / 配向性 / 心筋再生 / 微細加工 … More
Except Principal Investigator
細胞シート / 組織工学 / poly(N-isopropylacrylamide) / 細胞シートのマニピュレーション / 温度応答性表面 / ポリ(N-イソプロピルアクリルアミド) / 再生医療 / 肝細胞 / 温度応答性培養皿 / 細胞シート工学 / 温度応答性高分子 / 薬剤モデル / 風船様変性 / NASH / 非アルコール性脂肪肝炎 / 血管網付与 / 心筋細胞 / ヒト組織モデル / 組織モデル / フォトリソグラフィー / 肝様組織構造 / 微細加工 / 肝組織様構造 / 微細加工技術 / 肝小葉 / 成長因子 / 肝細胞シート / 軟組織 / 共培養 / 温度応答性細胞培養表面 / Connexin / Gap junction / Electrical coupling / Temperature-responsive dish / Cell sheet / 心筋細胞シート / コネキシン / ギャップ結合 / 電気的結合 / Cell growth factor / Temperature responsive cell culture dish / Serum free / Regenerative medicine / Tissue engineering / シナジー配列 / RGD / フィブロネクチン / インスリン / 細胞成長因子 / 無血清培養 / bioartificial kidney / urinary tubule / kidney epithelial cell / cell sheet manipulation / temperature-responsive surface / バイオ人工腎 / 尿細管 / 腎上皮細胞 / cell sheet engineering / regenerative medicine / tissue engineering / stem cell / cornea / thermoresponsive polymers / 基底膜 / 細胞間接着 / 移植 / ディスパーゼ / 角膜上皮細胞 / 幹細胞 / 角膜 / patterned domain sizes / urea synthesis / albumin production / endothelial cells / parenchymal cells / pattern co-culture / patterned thermoresponsive surfaces / 相転移挙動 / パターンサイズ / 尿素合成能 / アルブミン産生 / 血管内皮細胞 / 肝実質細胞 / パターン化共培養 / パターン化温度応答性表面 / 循環シミュレータ / 血圧測定 / リニアアレイセンサー / 人工臓器 Less
  • Research Projects

    (14 results)
  • Research Products

    (31 results)
  • Co-Researchers

    (28 People)
  •  Development of human NASH model with balloon degeneration

    • Principal Investigator
      坂口 勝久
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Tokyo City University
  •  低温灌流培養と血管網付膵島β細胞シートを用いた立体的膵島β細胞組織構築法の確立Principal Investigator

    • Principal Investigator
      清水 達也
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Tokyo Women's Medical University
  •  Development of engineered 3D tissue constructs having photosynthetic capacityPrincipal Investigator

    • Principal Investigator
      SHIMIZU Tatsuya
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Tokyo Women's Medical University
  •  Elucidation of blood (liquid) flow effect on human renal development by renal organoid with perfusion culture systemPrincipal Investigator

    • Principal Investigator
      Shimizu Tatsuya
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Tokyo Women's Medical University
  •  In vitro fabrication of Human heart tissue model with perfusable blood vessels

    • Principal Investigator
      Sekine Hidekazu
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Tokyo Women's Medical University
  •  Fabrication of structually comlicated soft tissue such as liver-tissues and understanding its biological function of teh fabricated liver-tissue

    • Principal Investigator
      YAMATO MASAYUKI
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      Tokyo Women's Medical University
  •  Development of newly designed pressure sensor for regenerative medicine and artificial organs

    • Principal Investigator
      FUJIMOTO Tetsuo
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Shibaura Institute of Technology
  •  細胞シートと組織還流培養装置を用いた血管付き心筋組織の再生Principal Investigator

    • Principal Investigator
      清水 達也
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Tokyo Women's Medical University
  •  Development of novel intelligent tissue culture surfaces to accelerate cell proliferation and recover cell sheet under serum free conditions, using physiologically active peptides

    • Principal Investigator
      OKANO Teruo
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Tokyo Woman's Medical University
  •  The electrophysiological analyses of layered cardiomyocyte sheets

    • Principal Investigator
      HARAGUCHI Yuji
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Tokyo Women's Medical University
  •  微細加工技術による心筋細胞への配向性の付与と3次元培養法の確立Principal Investigator

    • Principal Investigator
      清水 達也
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Tokyo Women's Medical University
  •  Development of novel co-culture system of parenchymal cells and nonparenchymal cells on thermoresponsive polymer-grafted dish surfaces

    • Principal Investigator
      OKANO Teruo
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Tokyo Women's Medical University
  •  Development of Transplantable Corneal Epithelium Fabricated with Cell Sheet Engineering

    • Principal Investigator
      YAMATO Masayuki
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Tokyo Women's Medical University
  •  Development of Cultured Renal Tubules with Cell Sheet Engineering

    • Principal Investigator
      YAMATO Masayuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Tokyo Women's Medical University

All 2023 2019 2018 2017 2016 2015 2014 2013 2008 2006 2005 Other

All Journal Article Presentation Book Patent

  • [Book] Cardiovascular Regeneration Therapies Using Tissue Engineering Approaches2005

    • Author(s)
      T.Shimizu et al.
    • Total Pages
      238
    • Publisher
      Springer-Verlag Tokyo
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16500270
  • [Journal Article] Tricultured Cell Sheets Develop into Functional Pancreatic Islet Tissue with a Vascular Network2023

    • Author(s)
      Homma Jun、Sekine Hidekazu、Shimizu Tatsuya
    • Journal Title

      Tissue Engineering Part A

      Volume: 29 Issue: 7-8 Pages: 211-224

    • DOI

      10.1089/ten.tea.2022.0167

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K12654, KAKENHI-PROJECT-23K25198
  • [Journal Article] The bioengineering of perfusable endocrine tissue with anastomosable blood vessels2023

    • Author(s)
      Yago Hiroki、Homma Jun、Sekine Hidekazu、Higashi Yuhei、Sakurai Hiroyuki、Shimizu Tatsuya
    • Journal Title

      Biofabrication

      Volume: 15 Issue: 4 Pages: 045010-045010

    • DOI

      10.1088/1758-5090/ace9fc

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K12654, KAKENHI-PROJECT-23K25198
  • [Journal Article] Perfusion culture maintained with an air-liquid interface to stimulate epithelial cell organization in renal organoids in vitro2019

    • Author(s)
      Sekiya Sachiko、Kikuchi Tetsutaro、Shimizu Tatsuya
    • Journal Title

      BMC Biomedical Engineering

      Volume: 1 Issue: 1 Pages: 1-15

    • DOI

      10.1186/s42490-019-0017-9

    • NAID

      120006765059

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H02089
  • [Journal Article] Pathological Process of Prompt Connection between Host and Donor Tissue Vasculature Causing Rapid Perfusion of the Engineered Donor Tissue after Transplantation.2018

    • Author(s)
      Sekiya S, Morikawa S, Ezaki T, Shimizu T.
    • Journal Title

      Int J Mol Sci.

      Volume: 19 Issue: 12 Pages: 4102-4102

    • DOI

      10.3390/ijms19124102

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H02089
  • [Journal Article] Induction of vasculature in engineered three-dimensional tissue2017

    • Author(s)
      Sekiya Sachiko, Shimizu Tatsuya
    • Journal Title

      Inflammation and Regeneration

      Volume: 37 Issue: 1

    • DOI

      10.1186/s41232-017-0055-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H02089
  • [Journal Article] Anisotropic cellular network formation in engineered muscle tissue through the self-organization of neurons and endothelial cells2015

    • Author(s)
      Hironobu Takahashi, Tatsuya Shimizu, Masamichi Nakayama, Masayuki Yamato, Teruo Okano
    • Journal Title

      Advanced Healthcare Materials

      Volume: 4 Issue: 3 Pages: 356-360

    • DOI

      10.1002/adhm.201400297

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26702018, KAKENHI-PLANNED-23106009
  • [Journal Article] The use of anisotropic cell sheets to control orientation during the self-organization of 3D muscle tissue2013

    • Author(s)
      Takahashi H, Shimizu T, Nakayama M, Yamato M, Okano T
    • Journal Title

      Biomaterials

      Volume: 34 Issue: 30 Pages: 7372-7380

    • DOI

      10.1016/j.biomaterials.2013.06.033

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106009
  • [Journal Article] Development of a simple device for transfer/transplantation of living cell sheets rapidly and completely without cell damage2013

    • Author(s)
      K. Tadakuma, N. Tanaka, Y. Haraguchi, M. Higashimori, M. Kaneko, T. Shimizu, M. Yamato, and T. Okano
    • Journal Title

      Biomaterials

      Volume: 34 Pages: 9018-25

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106009
  • [Journal Article] 心筋に対する再生医療2006

    • Author(s)
      清水達也
    • Journal Title

      臨床看護 32・8

      Pages: 1136-1143

    • Data Source
      KAKENHI-PROJECT-17700404
  • [Journal Article] Polysurgery of cell sheet grafts overcomes diffusion limits to produce thick, vascularized myocardial tissues2006

    • Author(s)
      Tatsuya Shimizu
    • Journal Title

      Faseb J in press

    • Data Source
      KAKENHI-PROJECT-17700404
  • [Journal Article] 心筋再生の現状と今後の展望2005

    • Author(s)
      清水達也
    • Journal Title

      再生医療 4・3

      Pages: 383-390

    • Data Source
      KAKENHI-PROJECT-17700404
  • [Journal Article] Cell sheet technology for myocardial tissue engineering2005

    • Author(s)
      T.Shimizu et al.
    • Journal Title

      Cardiovascular Regeneration Therapies Using Tissue Engineering Approaches

      Pages: 45-52

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16500270
  • [Journal Article] Long-term survial and growth of pulsataile myocardial tissue grafts engineered by the layering of ccardiomyocyte sheets

    • Author(s)
      T.Shimizu et al.
    • Journal Title

      Tissue Engineering (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16500270
  • [Journal Article] Long-term survival and growth of pulsataile myocardial tissue grafts engineered by the layering of cardiomyocyte sheets

    • Author(s)
      T.Shimizu et al.
    • Journal Title

      Tissue Engineering (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16500270
  • [Journal Article] Long-term survival and growth of pulsataile myocardial tissue grafts engineered by the layering of cardiomyocyte sheets

    • Author(s)
      T.Shimizu et al.
    • Journal Title

      Tissue Engineering (in press)

    • Data Source
      KAKENHI-PROJECT-16500270
  • [Patent] オルガノイドの培養方法、並びにオルガノイド培養デバイス及びシステム2018

    • Inventor(s)
      関谷佐智子、菊地鉄太郎、清水達也
    • Industrial Property Rights Holder
      関谷佐智子、菊地鉄太郎、清水達也
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-17H02089
  • [Presentation] 32℃環境灌流培養における栄養および機能血管を有する内分泌組織構築と移植2023

    • Author(s)
      矢後博基, 本間順, 関根秀一, 東祐平, 清水達也
    • Organizer
      第22回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-23K25198
  • [Presentation] 膵島様組織構築のための血管内皮共培養膵β細胞シートにおける内皮細胞の役割2023

    • Author(s)
      本間順, 矢後博基, 関根秀一, 清水達也
    • Organizer
      第22回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-23K25198
  • [Presentation] 間欠的加圧による血管内皮共培養系での血管網付与効果の検討2023

    • Author(s)
      勝浦美沙子, 本間 順, 東 祐平, 関根秀一, 清水達也
    • Organizer
      第22回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-23K25198
  • [Presentation] 高細胞密度の立体組織への灌流可能な栄養血管網導入を実現する灌流培養技術の開発2023

    • Author(s)
      戸部友輔, 本間順, 関根秀一, 坂口勝久, 岩崎清隆, 清水達也
    • Organizer
      第22回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-23K25198
  • [Presentation] 細胞シート工学を用いたBallooned hepatocyteの解明2023

    • Author(s)
      蓮井 宣宏 , 坂口 勝久 , 阪本 良弘 , 清水 達也
    • Organizer
      日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-23K11815
  • [Presentation] 間欠的加圧培養の細胞への影響検証と血管網豊富な移植組織の構築2023

    • Author(s)
      勝浦美沙子、本間順、東祐平、高木亮、関根秀一、永田智、清水達也
    • Organizer
      第23回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-23K25198
  • [Presentation] Analysis of metabolic activity using the engineered heart tissue model2017

    • Author(s)
      Hidekazu Sekine, Tatsuya Shimizu
    • Organizer
      Keystonesymposia Mitochondria Communication
    • Place of Presentation
      Taos, New Mexico, USA
    • Year and Date
      2017-01-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350517
  • [Presentation] Ex vivo engineering of vascularized heart tissue model2016

    • Author(s)
      Hidekazu Sekine, Tatsuya Shimizu
    • Organizer
      European Chapter Meeting of the Tissue Engineering and Regenerative Medicine International Society 2016
    • Place of Presentation
      Uppsala, Sweden
    • Year and Date
      2016-06-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350517
  • [Presentation] Ex vivo fabrication of heart tissue model with perfusable blood vessels using cell sheet2016

    • Author(s)
      Hidekazu Sekine, Tatsuya Shimizu
    • Organizer
      Basic Cardiovascular Sciences (BCVS) Scientific Sessions 2016
    • Place of Presentation
      Phoenix, Arizona, USA
    • Year and Date
      2016-07-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350517
  • [Presentation] Fabrication of vascularized 3-D heart tissue model for drug evaluation2015

    • Author(s)
      Hidekazu Sekine, Tatsuya Shimizu
    • Organizer
      World Conference on Regenerative Medicine
    • Place of Presentation
      Congress Center Leipzig
    • Year and Date
      2015-10-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350517
  • [Presentation] The Model of Vascularized Three Dimensional Heart Tissue for Drug Evaluation2015

    • Author(s)
      Hidekazu Sekine, Tatsuya Shimizu
    • Organizer
      2015 4th TERMIS World Congress
    • Place of Presentation
      The Boston Marriott Copley Place
    • Year and Date
      2015-09-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350517
  • [Presentation] Stem Cell Separation using Thermoresponsive Copolymer Brushes having Cationic Charge2015

    • Author(s)
      Nagase K., Hatakeyama Y., Shimizu T., Matsuura K., Yamato M., Takeda N., Okano T
    • Organizer
      2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)
    • Place of Presentation
      Noyori Memorial Hall, Nagoya University, Nagoya
    • Year and Date
      2015-11-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23106009
  • [Presentation] Construction of cell sheet-based 3D tissues with designed cell orientation using anisotropic cell sheets2014

    • Author(s)
      Hironobu Takahashi, Tatsuya Shimizu, Masamichi Nakayama, Masayuki Yamato, Teruo Okano
    • Organizer
      5th 2014 International Symposium on Micro-NanoMechatronics and Human Science
    • Place of Presentation
      Nagoya, Aichi
    • Year and Date
      2014-11-11
    • Data Source
      KAKENHI-PLANNED-23106009
  • [Presentation] 移植再生心筋組織における血管新生の経時的観察2008

    • Author(s)
      近藤広基、清水達也、藤本哲男、他
    • Organizer
      第7回日本再生医療学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-03-14
    • Data Source
      KAKENHI-PROJECT-18591561
  • 1.  YAMATO Masayuki (40267117)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 4 results
  • 2.  AKIYAMA Yoshikatsu (20349640)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  OKANO Teruo (00130237)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  KIKUCHI Akihiko (40266820)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  KUSHIDA Ai (10338981)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  NAKAYAMA Masamichi (00338980)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 7.  HARAGUCHI Yuji (80272251)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  SHIMIZU Tatsuya (70468867)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 9.  Sekine Hidekazu (60541737)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 12 results
  • 10.  青柳 隆夫 (40277132)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  FUJIMOTO Tetsuo (50267473)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  UMEZU Mitsuo (90132927)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  NISHIDA Hiroshi (50147427)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SHIRAISHI Yasuyuki (00329137)
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  • 15.  YOKOYAMA Masayuki (20220577)
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  • 18.  KOBAYASHI Jun (20385404)
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  • 19.  NAGASE Kenichi (10439838)
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