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KUMADA Maki  熊田 真樹

ORCIDConnect your ORCID iD *help
Researcher Number 40326830
External Links
Affiliation (based on the past Project Information) *help 2011: 自治医科大学, 医学部・医学科, 准教授
2009 – 2011: 自治医科大学, 医学部, 准教授
2006 – 2007: 自治医科大学, 医学部, 助教
2006: 自治医科大学, 医学部, 講師
2000 – 2005: Jichi Medical School, Dept. of Medicine, Assist. Professor, 医学部, 助手
Review Section/Research Field
Principal Investigator
Legal medicine
Except Principal Investigator
Legal medicine / Legal medicine / Hematology / Medical sociology / Anesthesiology/Resuscitation studies
Keywords
Principal Investigator
ノックアウトマウス / 分子遺伝学 / 血液型
Except Principal Investigator
Rh variant / linear peptide / mimotope / ラットABOオーソログ / ラットABHオーソログ / トランスジェニックラット / ラットABH抗原 … More / Molecular evolution / Recombination / Nucleotide substitution / Rh blood group system / 分子進化 / 組換え / Rh変異型 / Rh式血液型システム / 自己免疫性溶血性貧血 / Weak D / Rh血液型 / 変異型 / Rh式血液型 / 遺伝子多型 / type2 diabetes / association stud / retinol binding protein 4 / inflammation / Hypertension / genome bank / 間質性肺炎 / 本態性高血圧 / ゲノムバンク / 糖尿病 / 肥満 / 新生児死亡 / 炎症 / トランスジェニックマウス / molecular mimicry / band 3 / random peptide library / autoantibody / Rh blood groups / autoimmune hemolytic anemia / 交叉反応 / CD47 / Coombs陰性自己免疫性溶血性貧血 / ミモトープ / 分子相同性 / バンド3 / ランダムペプチドライブラリー / 抗赤血球自己抗体 / Chromosome mapping / Polymorphisms / Orthologous RH gene superfamily / RH superfamily / orthologous RH gene superfami1y / 染色体マッピング / 多型 / orthologous RH gene superfamily / 塩基置換 / rat ABO antigen / ABO evolution / transplantation / ABO transgenic rat / 移植抗原 / transgenic rat / ABH antigen expression / paralogous gene / rat ABO homologue / ABOオーソログ / single nucleotide polymorphisms / microsatellite / Rh genotyping / Gaps / Rhgenotyping法 / マイクロサテライト多型 / 一塩基多型 / Rh genotyping法 / 塩基置換・gap / Mouse genome / RHCE gene / RHD gene / Molecular genetics / Partial D / Rh blood group / Rhmod / エピトープ / weak D / マウスオーソログ / Rh30遺伝子 / マウスゲノム / RHCE遺伝子 / RHD遺伝子 / 分子遺伝学 / partial D / genetic analysis / variant / epitope / enhancer / promoter / RHAG gene / RH gene / Rh blood system / 遺伝子解析 / 抗原エピトープ / エンハンサー / プロモーター / RHAG遺伝子 / RH遺伝子 / 生活習慣 / GNB3 / 遺伝子検査 / 塩分摂取 / SNP / 遺伝子 / 高血圧 / 地域差 / 遺伝子頻度 / 健康教育 / 行動変容 / 生活習慣病 / 遺伝子情報 / 術後痛 / 癌 / 術後悪心・嘔吐 / 術後鎮痛 / オピオイド Less
  • Research Projects

    (11 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (18 People)
  •  Exploratory study of a usability of gene information on the health promotion and prevention of disease in the community setting

    • Principal Investigator
      OKAYAMA Masanobu
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical sociology
    • Research Institution
      Jichi Medical University
  •  オピオイド受容体関連遺伝子の遺伝子多型とオピオイドの鎮痛効果及び副作用との関連

    • Principal Investigator
      井上 荘一郎
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Jichi Medical University
  •  Molecularr epidemiology about unexpected sudden death

    • Principal Investigator
      IWAMOTO Sadahiko
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Legal medicine
    • Research Institution
      Jichi Medical University
  •  Development of model animal to reveal the antibody production for ABO blood group antigens.

    • Principal Investigator
      IWAMOTO Sadahiko
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Jichi Medical School
  •  The analysis of Rh antigen (polypeptide) function and the molecular evolution of orthologous RH genes in various species.

    • Principal Investigator
      OKUDA Hiroshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Jichi Medical School
  •  The study on the mechanism of production of autoantibodies in autoimmune hemolytic anemia.

    • Principal Investigator
      KAMESAKI Toyomi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  Rh蛋白複合体関連遺伝子ノックアウトマウスの作成とその遺伝学・生物学的解析Principal Investigator

    • Principal Investigator
      熊田 真樹
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Legal medicine
    • Research Institution
      Jichi Medical University
  •  Further investigation on the Rh blood group system for the expression of the RH gene and the epitopes of the Rh antigens

    • Principal Investigator
      KAJII Eiji
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Legal medicine
    • Research Institution
      Jichi Medical School
  •  The molecular genetic analysis and its application of single nucleotide polymorphisms and microsatellite in both RH genes.

    • Principal Investigator
      OKUDA Hiroshi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Jichi Medical School
  •  Establishment of transgenic rat expressing human A or B Transferase gene and cloning of rat paralogous genes equivalent of human histo-blood group ABO gene.

    • Principal Investigator
      IWAMOTO Sadahiko
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Jichi Medical School
  •  Molecular genetical analysis of the epitopes on Rh blood group antigen and establishment of genetic examination system in RH genes.

    • Principal Investigator
      KAJII Eiji
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Legal medicine
    • Research Institution
      Jichi Medical School

All 2010 2007 2006 2005 2004 2003 Other

All Journal Article Presentation

  • [Journal Article] Regulatory SNP in the RBP4 gene modified the expression in adipocytes and associated with BMI2010

    • Author(s)
      熊田真樹, 他
    • Journal Title

      Obesity 18

      Pages: 1006-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390168
  • [Journal Article] Regulatory SNP in the RBP4 gene modified the expression in adipocytes and associated with BMI2010

    • Author(s)
      Munkhtulga L, Kumada M(8番目), et al(18名)
    • Journal Title

      Obesity

      Volume: 18 Pages: 1006-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390168
  • [Journal Article] Identification of a regulatory SNP in the retinol binding protein 4 gene associated with type 2 diabetes in Mongolia.2007

    • Author(s)
      Munkhtulga L, Nakayama K, Utsumi N, Yanagisawa Y, Gotoh T, Omi T, Kumada M, Erdenebulgan B, Zolzaya K, Lkhagvasuren T, Iwamoto S.
    • Journal Title

      Hum Genet. 120

      Pages: 879-888

    • Data Source
      KAKENHI-PROJECT-17390205
  • [Journal Article] An intronic variable number of tandem repeat polymotphisms of the cold-induced autoinflammatory syndrome 1(CIAS1) gene modifies gene expression and is associated with essential hypertension.2006

    • Author(s)
      Omi T, Kumada M, Kamesaki T, Okuda H, Munkhtulga L, Yanagisawa Y, Utsumi N, Gotoh T, Hata A, Soma M, Umemura S, Ogihara T, Takahashi N, Tabara Y, Shimada K, Mano H, Kajii E, Miki T, Iwamoto S.
    • Journal Title

      Eur J Hum Genet. 14

      Pages: 1295-305

    • Data Source
      KAKENHI-PROJECT-17390205
  • [Journal Article] CATERPILLER遺伝子群のSNPタイピングによる本態性高血圧との関連解析2006

    • Author(s)
      北村歌奈子, 近江俊徳, 熊田真樹, 後藤孝也, 宇津見七海, ウハグワスレンムンフトルガ, 坂本敦司, 岩本禎彦
    • Journal Title

      DNA多型 14

      Pages: 264-266

    • Data Source
      KAKENHI-PROJECT-17390205
  • [Journal Article] Genetic heterogeneity in a susceptible region for essential hypertension among demographically different local populations in Japan2005

    • Author(s)
      Kumada M.
    • Journal Title

      Community Genet 11

      Pages: 150-9

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390205
  • [Journal Article] Aly/REF, a factor for mRNA transport, activates RH gene promoter function.2005

    • Author(s)
      Suganuma H, Kumada M, Omi T, Gotoh T, Lkhagvasuren M, Okuda H, Kamesaki T, Kajii E, Iwamoto S.
    • Journal Title

      FEBS J. 272

      Pages: 2696-2704

    • Data Source
      KAKENHI-PROJECT-17390205
  • [Journal Article] cDNA cloning, mapping and polymorphism of the porcine Rhesus(RH) gene.2004

    • Author(s)
      Omi T, Kumada M, Kamesaki T, Okuda H, Kajii E, Iwamoto S, Vogeli P, Schelling C, Stranzinger G
    • Journal Title

      DNA Polymorphism 12

      Pages: 12-15

    • NAID

      10013660627

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591018
  • [Journal Article] ブタRhesus(RH)遺伝子のcDNAクローニング、マッピング、多型解析2004

    • Author(s)
      近江俊徳, 熊田真樹, 亀崎豊実, 奥田浩, 梶井英治, 岩本禎彦
    • Journal Title

      DNA多型 12

      Pages: 12-15

    • Data Source
      KAKENHI-PROJECT-15591018
  • [Journal Article] cDNA cloning, mapping and polymorphism of the porcine Rhesus (RH) gene.2004

    • Author(s)
      Omi T, Kumada M, Kamesaki T, Okuda H, Kajii E, Iwamoto S, Voegeli P, Stranzinger G, Neuenshwander S
    • Journal Title

      DNA polymorphism 12

      Pages: 262-263

    • NAID

      10013660627

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590587
  • [Journal Article] A novel mutation in the RHD gene in Japanese individuals with weak D, encoding an amino acid change in the 11th transmembranous domain of the RhD protein transmembranous portion of the RhD protein.2003

    • Author(s)
      Kamesaki T, Kumada M, Omi T, Okuda H, Iwamoto S, Takahashi J, Kimura K, Hirayama F, Kamata H, Obara K, Taniguchi M, Tani Y, Kajii E.
    • Journal Title

      Vox Sang. 84

      Pages: 141-141

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591018
  • [Journal Article] A novel mutation in the RHD gene in Japanese individuals with weak D, encoding an amino acid change in the 11th transmembranous domain of the RhD protein.2003

    • Author(s)
      Kamesaki T, Kumada M, Omi T, Okuda H, Iwamoto S, Takahashi J, Kimura K, Hirayama F. Kamata H, Obara K, Taniguchi M, Tani Y, Kajii E.
    • Journal Title

      Vox Sang 84

      Pages: 141-141

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590586
  • [Journal Article] Gene duplication and polymorphism of rat ABO homologue.2003

    • Author(s)
      S.Iwamoto, M.Kumada.T.Kamesaki, H.Okuda, E.Kajii.
    • Journal Title

      DNA polymorphism 11

      Pages: 38-41

    • NAID

      10013995330

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590586
  • [Journal Article] A novel mutation in the RHD gene in Japanese individuals with weak D, encoding an amino acid change in the 11th transmembranous domain of the RhD protein transmembranous portion of the RhD protein.2003

    • Author(s)
      Kamesaki T, Kumada M, Omi T, Okuda H, Iwamoto S, Takahashi J, Kimura K, Hirayama F, Kamata H, Obara K, Taniguchi M, Tani Y, Kajii E
    • Journal Title

      Vox Sang 84

      Pages: 141-141

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590587
  • [Journal Article] Gene duplication and polymorphism of rat ABO homologue.2003

    • Author(s)
      Iwamoto S, Kumada M, Kamesaki T, Okuda H, Kajii E.
    • Journal Title

      DNA Polymorphism 11

      Pages: 38-41

    • NAID

      10013995330

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591018
  • [Journal Article] DNA-based identification resolved suspected misdiagnosis due to contaminated cytological specimens.2003

    • Author(s)
      Iwamoto S, Kamesaki T, Kumada M, Omi T, Okuda H, Hasegawa T, Sakural S, Kajii E
    • Journal Title

      Legal Medicine 5

      Pages: 246-250

    • NAID

      50000002091

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590587
  • [Journal Article] DNA-based identification resolved suspected misdiagnosis due to contaminated cytological specimens.2003

    • Author(s)
      Iwamoto S, Kamesaki T, Kumada M, Omi T, Okuda H, Hasegawa T, Sakurai S, Kajii E.
    • Journal Title

      Leg Med 5

      Pages: 246-250

    • NAID

      50000002091

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590586
  • [Journal Article] DNA-based identification resolved suspected misdiagnosis due to contaminated cytological specimens.2003

    • Author(s)
      Iwamoto S, Kamesaki T, Kumada M, Omi T, Okuda H, Hasegawa T, Sakurai S, Kajii E.
    • Journal Title

      Leg Med 5

      Pages: 246-250

    • NAID

      50000002091

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591018
  • [Journal Article] Gene duplication and polymorphism of rat ABO homologue.2003

    • Author(s)
      Iwamoto S, Kumada M, Kamesaki T, Okuda H, Kajii E
    • Journal Title

      DNA polymorphism 11

      Pages: 38-41

    • NAID

      10013995330

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590587
  • [Journal Article] Aly/REF, a factor for mRNA transport, activates RH gene promoter function

    • Author(s)
      Hiroshi Suganuma, Maki Kumada, Toshinori Omi, Takaya Gotoh, Munkhtulga Lkhagvasuren, Hiroshi Okuda, Toyomi Kamesaki, Eiji Kajii, Sadahiko Iwamoto
    • Journal Title

      FEBS J (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590586
  • [Journal Article] Identification and characterization of novel peroxisome proliferators activated receptor gamma(PPARγ) transcriptional variants in pig and human.

    • Author(s)
      Omi T, Kumada M, Gotoh T, Kamesaki T, Okuda H, Kajii E, Iwamoto S.
    • Journal Title

      DNA polymorphism (in press)

    • NAID

      10015685709

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590586
  • [Presentation] Comparative study of polymorphisms on Genes associated with lifestyle related diseases in Asian and Pacific populations.2007

    • Author(s)
      Nakayama K, Munkhtulga L, Yanagisawa Y, Utsumi N, Kumada M, Gotoh T, jwamoto S, Kagawa Y
    • Organizer
      The 39th conference of Asia-Pacific academic consortium for public health.
    • Place of Presentation
      坂戸
    • Year and Date
      2007-11-24
    • Data Source
      KAKENHI-PROJECT-17390205
  • [Presentation] トルコ鞍部・下垂体出血によって受傷約2週間後に急変・死亡したと推定される1例2007

    • Author(s)
      坂本 敦司、小山 田隆、岩本 禎彦、熊田 真樹、後藤 孝也、村田 一素、奥田 浩、梶井 英治
    • Organizer
      第13回遺伝診療学会
    • Place of Presentation
      松山
    • Year and Date
      2007-07-28
    • Data Source
      KAKENHI-PROJECT-17390205
  • 1.  KJII Eiji (40204391)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 12 results
  • 2.  KAMESAKI Toyomi (90316513)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 14 results
  • 3.  IWAMOTO Sadahiko (10232711)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 19 results
  • 4.  OKUDA Hiroshi (50285772)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 14 results
  • 5.  OMI Toshnori (40296091)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 15 results
  • 6.  OKAYAMA Masanobu (10285801)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  KOMATSU Kenichi (70364510)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KANDA Takefumi (10528673)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  TAKESHIMA Tarou (50554565)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KENZAKA Tsuneaki (90437492)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  FUKUI Emiko (20208341)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  GOTOH Takaya (80284355)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 13.  SAKAMOTO Atsushi (80235168)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 14.  井上 荘一郎 (20322399)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  茂木 康一 (80344919)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  瀬尾 憲正 (40093257)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  堀田 訓久 (70322401)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  今野 和典 (40528676)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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