IWANAMI AKIO 岩波明生

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IWANAMI Akio 岩波明生

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Researcher Number	40327557
Affiliation (based on the past Project Information) *help	2016 – 2018: 慶應義塾大学, 医学部(信濃町), 講師 2012 – 2015: 慶應義塾大学, 医学部, 助教 2008: Clinical research Center, National Hospital Organization Murayama Medical Center, 整形外科, 医員 2008: Clinical research Center, National Hospital Organization Murayama Medical Center 2007: Clinical research Center, National Hospital Organization Murayama Medical Center, 整形外科, 医員
Review Section/Research Field	Principal Investigator Orthopaedic surgery Except Principal Investigator Cardiovascular surgery
Keywords	Principal Investigator 脊髄損傷 / 腫瘍化 / 再生医療 / iPS細胞 / 神経幹細胞 / 脳・神経疾患 / Glioblastoma / 脳腫瘍 / 脊髄腫瘍 / PML … More / 分子標的療法 / グリオーマ / 慢性期治療 / GSK3β-inhibitor / 細胞移植療法 / 急性期治療 / 軸索再生 / 脳・神経 / 移植・再生医療 … More Except Principal Investigator 外科学 / 対麻痺 / 脊髄虚血 / 虚血性脊髄損傷 / HGF / 脊髄障害 / 胸腹部大動脈瘤 Less

Treatment for spinal cord ischemia by HGF
- Principal Investigator
  
  Yoshitake Akihiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Saitama Medical University
  Keio University
Assessment of tumorigenic potential of human induced pluripotent stem cell-derived neural stem/progenitor cells for spinal cord injuryPrincipal Investigator
- Principal Investigator
  
  IWANAMI AKIO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Keio University
Molecularly targeted therapy for GlioblastomaPrincipal Investigator
- Principal Investigator
  
  IWANAMI AKIO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Keio University
Enhancement of Axonal Regeneration by Administration of GSK3β-inhibitor Spinal Cord Injured MicePrincipal Investigator
- Principal Investigator
  
  IWANAMI Akio
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Clinical research Center, National Hospital Organization Murayama Medical Center

All 2017 2016 2015 2013 2012 Other

All Journal Article Presentation

[Journal Article] Low immunogenicity of mouse induced pluripotent stem cell-derived neural stem/progenitor cells.2017
- Author(s)
  Itakura G, Ozaki M, Nagoshi N, Kawabata S, Nishiyama Y, Sugai K, Iida T, Kashiwagi R, Ookubo T, Yastake K, Matsubayashi K, Kohyama J, Iwanami A, Matsumoto M, Nakamura M, Okano H.
- Journal Title
  
  Sci Rep.
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10422
[Journal Article] Whole-Genome DNA Methylation Analyses Revealed Epigenetic Instability in Tumorigenic Human iPS Cell-Derived Neural Stem/Progenitor Cells.2017
- Author(s)
  Iida T, Iwanami A, Sanosaka T, Kohyama J, Miyoshi H, Nagoshi N, Kashiwagi R, Toyama Y, Matsumoto M, Nakamura M, Okano H.
- Journal Title
  
  Stem Cells
  
  Volume: 35 Issue: 5 Pages: 1316-1327
- DOI
  10.1002/stem.2581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10422, KAKENHI-PROJECT-26713047
[Journal Article] Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives.2017
- Author(s)
  Itakura G, Kawabata S, Ando M, Nishiyama Y, Sugai K, Ozaki M, Iida T, Ookubo T, Kojima K, Kashiwagi R, Yasutake K, Nakauchi H, Miyoshi H, Nagoshi N, Kohyama J, Iwanami A, Matsumoto M, Nakamura M, Okano H.
- Journal Title
  
  Stem Cell Reports.
  
  Volume: 8 Issue: 3 Pages: 673-684
- DOI
  10.1016/j.stemcr.2017.02.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10422, KAKENHI-PROJECT-16K09842
[Journal Article] Safe and efficient method for cryopreservation of human induced pluripotent stem cell-derived neural stem and progenitor cells by a programmed freezer with a magnetic field.2016
- Author(s)
  Nishiyama Y, Iwanami A, Kohyama J, Itakura G, Kawabata S, Sugai K, Nishimura S, Kashiwagi R, Yasutake K, Isoda M, Matsumoto M, Nakamura M, Okano H.
- Journal Title
  
  Neurosci Res.
  
  Volume: 107 Pages: 20-29
- DOI
  10.1016/j.neures.2015.11.011
- Data Source
  KAKENHI-PROJECT-15K10422
[Journal Article] Pathological classification of human iPSC-derived neural stem/progenitor cells towards safety assessment of transplantation therapy for CNS diseases.2016
- Author(s)
  Sugai K, Fukuzawa R, Shofuda T, Fukusumi H, Kawabata S, Nishiyama Y, Higuchi Y, Kawai K, Isoda M, Kanematsu D, Hashimoto-Tamaoki T, Kohyama J, Iwanami A, Suemizu H, Ikeda E, Matsumoto M, Kanemura Y, Nakamura M, Okano H.
- Journal Title
  
  Mol Brain.
  
  Volume: 9 Issue: 1 Pages: 85-85
- DOI
  10.1186/s13041-016-0265-8
- Data Source
  KAKENHI-PROJECT-15K10422
[Journal Article] Pretreatment with a γ-Secretase Inhibitor Prevents Tumor-like Overgrowth in Human iPSC-Derived Transplants for Spinal Cord Injury.2016
- Author(s)
  Okubo T, Iwanami A, Kohyama J, Itakura G, Kawabata S, Nishiyama Y, Sugai K, Ozaki M, Iida T, Matsubayashi K, Matsumoto M, Nakamura M, Okano H.
- Journal Title
  
  Stem Cell Reports.
  
  Volume: 7 Issue: 4 Pages: 649-663
- DOI
  10.1016/j.stemcr.2016.08.015
- Data Source
  KAKENHI-PROJECT-15K10422
[Journal Article] Arsenic reverses glioblastoma resistance to mTOR-targeted therapies2013
- Author(s)
  Iwanami A, Cloughesy TF, Cavenee WK, Mischel PS
- Journal Title
  
  Cell Cycle
  
  Volume: 10 Pages: 1473-1474
- Data Source
  KAKENHI-PROJECT-24791563
[Journal Article] PML mediates glioblastoma2013
- Author(s)
  岩波　明生
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 110 Pages: 4339-4344
- Data Source
  KAKENHI-PROJECT-24791563
[Presentation] ヒトiPS細胞を用いた脊髄再生医療に向けた安全性の確立2015
- Author(s)
  岩波明生
- Organizer
  日本脊髄障害医学会
- Place of Presentation
  グランドプリンスホテル高輪（東京都品川区）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-15K10422
[Presentation] 腫瘍抑制因子ＰＭＬをtargetとした星細胞腫の分子標的療法の開発（第１報）ＰＭＬによる星細胞腫の薬剤治療抵抗性の検討2012
- Author(s)
  岩波　明生
- Organizer
  第41回日本脊椎脊髄病学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24791563
[Presentation] 腫瘍抑制因子ＰＭＬをtargetとした星細胞腫の分子標的療法の開発（第１報）ＰＭＬによる星細胞腫の薬剤治療抵抗性の検討2012
- Author(s)
  岩波　明生
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24791563
[Presentation] 腫瘍抑制因子PMLをtargetとした星細胞腫の分子標的療法の開発　（第二報）PML標的による星細胞腫の薬剤感受性効果の検討
- Author(s)
  岩波明生、Paul S. Mischel、岡野栄之、戸山芳昭、中村雅也
- Organizer
  日本整形外科学会基礎学術集会
- Place of Presentation
  沖縄那覇
- Data Source
  KAKENHI-PROJECT-24791563
[Presentation] 腫瘍抑制因子PMLをtargetとした星細胞腫の分子標的療法の開発　（第二報）PML標的による星細胞腫の薬剤感受性効果の検討
- Author(s)
  岩波明生、Paul S. Mischel 、岡野栄之、戸山芳昭、中村雅也
- Organizer
  日本整形外科学会基礎学術集会
- Place of Presentation
  千葉幕張
- Data Source
  KAKENHI-PROJECT-24791563

1. Yoshitake Akihiro (70327550)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 志水秀行 (50226247)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. OKANO Hideyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. NAKAMURA Masaya

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. KOHYAMA Jun

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. NISHIMURA Soraya

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. NISHIYAMA Yuichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. SUGAI Keiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. IIDA Tsuyoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. OKUBO Toshiki

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. Mischel Paul

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

IWANAMI AKIO 岩波 明生

IWANAMI Akio 岩波 明生

Research Projects

Research Products

Co-Researchers

Treatment for spinal cord ischemia by HGF

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Assessment of tumorigenic potential of human induced pluripotent stem cell-derived neural stem/progenitor cells for spinal cord injuryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecularly targeted therapy for GlioblastomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Enhancement of Axonal Regeneration by Administration of GSK3β-inhibitor Spinal Cord Injured MicePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Low immunogenicity of mouse induced pluripotent stem cell-derived neural stem/progenitor cells.2017

Author(s)

Journal Title

Data Source

[Journal Article] Whole-Genome DNA Methylation Analyses Revealed Epigenetic Instability in Tumorigenic Human iPS Cell-Derived Neural Stem/Progenitor Cells.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Safe and efficient method for cryopreservation of human induced pluripotent stem cell-derived neural stem and progenitor cells by a programmed freezer with a magnetic field.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pathological classification of human iPSC-derived neural stem/progenitor cells towards safety assessment of transplantation therapy for CNS diseases.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pretreatment with a γ-Secretase Inhibitor Prevents Tumor-like Overgrowth in Human iPSC-Derived Transplants for Spinal Cord Injury.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Arsenic reverses glioblastoma resistance to mTOR-targeted therapies2013

Author(s)

Journal Title

Data Source

[Journal Article] PML mediates glioblastoma2013

Author(s)

Journal Title

Data Source

[Presentation] ヒトiPS細胞を用いた脊髄再生医療に向けた安全性の確立2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 腫瘍抑制因子ＰＭＬをtargetとした星細胞腫の分子標的療法の開発（第１報）ＰＭＬによる星細胞腫の薬剤治療抵抗性の検討2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 腫瘍抑制因子ＰＭＬをtargetとした星細胞腫の分子標的療法の開発（第１報）ＰＭＬによる星細胞腫の薬剤治療抵抗性の検討2012

Author(s)

Organizer

IWANAMI AKIO 岩波明生

IWANAMI Akio 岩波明生

[Presentation] 腫瘍抑制因子PMLをtargetとした星細胞腫の分子標的療法の開発　（第二報）PML標的による星細胞腫の薬剤感受性効果の検討

[Presentation] 腫瘍抑制因子PMLをtargetとした星細胞腫の分子標的療法の開発　（第二報）PML標的による星細胞腫の薬剤感受性効果の検討