NISHIDA Noriyuki 西田教行

… Alternative Names

Nishida Noriyuki 西田教行

西田教之ニシダノリユキ

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Researcher Number	40333520
Other IDs
External Links
Affiliation (Current)	2025: 長崎大学, 医歯薬学総合研究科(医学系), 教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 長崎大学, 医歯薬学総合研究科(医学系), 教授 2014 – 2016: 長崎大学, 医歯薬学総合研究科(医学系), 教授 2011: 長崎大学, 大学院・医歯薬学総合研究科, 准教授 2009 – 2011: 長崎大学, 大学院・医歯薬学総合研究科, 教授 2010: 長崎大学, 医歯薬学総合研究科, 教授 … More 2008: 医歯薬学総合研究科, 准教授 2008: 長崎大学, 医歯薬学総合研究科, 准教授 2007 – 2008: 長崎大学, 大学院・医歯薬学総合研究科, 准教授 2006: 長崎大学, 大学院医歯薬学総合研究科, 准教授 2006: Nagasaki University, Graduate School of Biomedical Sciences, Department of Microbiology and Immunology, Assistant Professor, 大学院医歯薬学総合研究科, 助教授 2005: 岐阜大学, 人獣感染防御研究センター, 助教授 2003 – 2004: 長崎大学, 大学院・医歯薬学総合研究科, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related / Medium-sized Section 52:General internal medicine and related fields Except Principal Investigator Neurology / Basic Section 56010:Neurosurgery-related / Virology / General pharmacology / Neurosurgery / Neurochemistry/Neuropharmacology / Nerve anatomy/Neuropathology / Radiation science / Science and Engineering
Keywords	Principal Investigator プリオン病 / 神経変性 / FK506 / ミクログリア / 神経疾患 / プリオン / アミロイド / 液相分離 Except Principal Investigator プリオン病 / プリオン … More / NMR / 血液脳関門 / 再生医療 / 移植 / 幹細胞 / 脳梗塞 / アルツハイマー病 / 感染機構 / 脳 / 神経細胞 / 精製 / 神経変性疾患 / アミロイド / 神経幹細胞 / 動脈内投与 / 血管内手術 / 幹細胞移植 / BBB / low-molecular weight PPS / PPS / prion / 低分子化 / 治療法開発 / クロイツフェルト・ヤコブ病 / 低分子ペントサン / ペントサンポリ硫酸 / drug discovery / conformation / prion strain / prion diseases / 海綿状変性 / 遺伝子改変マウス / プリオン類似蛋白 / 創薬 / 立体構造 / プリオン蛋白 / conformation diseaase / Alzheimer disease / prion disease / heparin / pentosan polysulfate / blood-brain barrier(BBB) / コンフォメーション病 / ヘパリン誘導体 / ペントサン / 低酸素 / 予防・治療法 / FK506 / 髄液検査 / real-time QUIC法 / 異常型PrP / 遺伝性プリオン病 / カルコン / 分子イメージング / SPECT / 神経細胞死 / 培養細胞 / タンパク質 / 感染症 / PMCA 法 / 14-3-3蛋白 / 総タウ蛋白 / 脳脊髄液検査 / PMCA / タウ蛋白 / 髄液診断 / 疎水性クラスター / 構造変換 / 細菌毒性 / βシート / オリゴマー / 部分ペプチド / 赤外吸収 / ナノ秒分光 / 温度ジャンプ / フォールディング Less

プリオン病発症に関わるミクログリア制御機構の解明Principal Investigator
- Principal Investigator
  
  西田教行
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Nagasaki University
Replication of sCJD in vtroPrincipal Investigator
- Principal Investigator
  
  Nishida Noriyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Nagasaki University
Regulatory mechanism for the hemisphere after stem cell transplantation following ischemic stroke
- Principal Investigator
  
  HORIE Nobutaka
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagasaki University
Synergic effect of medical and stem cell therapy for stroke
- Principal Investigator
  
  HORIE Nobutaka
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Nagasaki University
Sensitive detection of abnormal prion protein in genetic human prion diseases
- Principal Investigator
  
  ATARASHI Ryuichiro
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Nagasaki University
プリオン感染に関与する異常型プリオンタンパク質以外の因子解明
- Principal Investigator
  
  布施隆行
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Nagasaki University
Development of molecular probe for SPECT imaging of amyloid in the brain
- Principal Investigator
  
  NAKAYAMA Morio
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Nagasaki University
Identification of the novel factors relating to prion infection, and analysis of its molecular mechanisms
- Principal Investigator
  
  FUSE Takayuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Nagasaki University
Search of surrogate maker for diagnosis of CJD using CSFs collected by nationwide surveillance
- Principal Investigator
  
  SHIRABE Susumu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Nagasaki University
原子分解能かつナノ秒時間分解能でのプリオン・フォールディング反応の観測
- Principal Investigator
  
  KUWATA Kazuo
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Gifu University
Trial of development of therapeutic using PPS modified penetrating efficacy into brain.
- Principal Investigator
  
  SHIRABE Susumu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Nagasaki University
Structure-based drug designs for the treatment of prion disease
- Principal Investigator
  
  KATAMINE Shigeru
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Virology
- Research Institution
  Nagasaki University
Experimental-therapeutic potency of pentosan pofysulfate as an anti-prion and anti-dementia drug
- Principal Investigator
  
  NIWA Masami
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagasaki University

[Journal Article] Challenges Based on Antiplasmodial and Antiviral Activities of 7‐Chloro‐4‐aminoquinoline Derivatives2023
- Author(s)
  Mizuta Satoshi、Mosaddeque Farhana、Tun Mya Myat Ngwe、Teklemichael Awet Alem、Taniguchi Mayumi、Hosokawa Masashi、Yamaguchi Tomoko、Makau Juliann、Huy Nguyen Tien、Mizukami Shusaku、Nishida Noriyuki、Morita Kouichi、Hirayama Kenji
- Journal Title
  
  ChemMedChem
  
  Volume: 18 Issue: 7
- DOI
  10.1002/cmdc.202200586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H04285, KAKENHI-PROJECT-20H00620, KAKENHI-PROJECT-23K21396, KAKENHI-PROJECT-23K28190
[Journal Article] Stem Cell Therapy for Acute/Subacute Ischemic Stroke with a Focus on Intraarterial Stem Cell Transplantation: From Basic Research to Clinical Trials2022
- Author(s)
  Yamaguchi Susumu、Yoshida Michiharu、Horie Nobutaka、Satoh Katsuya、Fukuda Yuutaka、Ishizaka Shunsuke、Ogawa Koki、Morofuji Yoichi、Hiu Takeshi、Izumo Tsuyoshi、Kawakami Shigeru、Nishida Noriyuki、Matsuo Takayuki
- Journal Title
  
  Bioengineering
  
  Volume: 10 Issue: 1 Pages: 33-33
- DOI
  10.3390/bioengineering10010033
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09328, KAKENHI-PROJECT-20K09351, KAKENHI-PROJECT-20KK0254, KAKENHI-PROJECT-23K21396
[Journal Article] Detection of Prions in a Cadaver for Anatomical Practice2022
- Author(s)
  Nakagaki Takehiro、Kaneko Miho、Satoh Katsuya、Murai Kiyohito、Saiki Kazunobu、Matsumoto Gen、Ogami-Takamura Keiko、Ikematsu Kazuya、Akagi Akio、Iwasaki Yasushi、Tsurumoto Toshiyuki、Nishida Noriyuki
- Journal Title
  
  New England Journal of Medicine
  
  Volume: 386 Issue: 23 Pages: 2245-2246
- DOI
  10.1056/nejmc2204116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07276, KAKENHI-PROJECT-21K07417, KAKENHI-PROJECT-20K16183, KAKENHI-PLANNED-18H05414, KAKENHI-PUBLICLY-22H04651, KAKENHI-PROJECT-23K21396, KAKENHI-PROJECT-23K24214
[Journal Article] Conformation-Dependent Influences of Hydrophobic Amino Acids in Two In-Register Parallel β-Sheet Amyloids, an α-Synuclein Amyloid and a Local Structural Model of PrPSc2022
- Author(s)
  Otaki Hiroki、Taguchi Yuzuru、Nishida Noriyuki
- Journal Title
  
  ACS Omega
  
  Volume: 7 Issue: 35 Pages: 31271-31288
- DOI
  10.1021/acsomega.2c03523
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16058, KAKENHI-PROJECT-23K21396
[Journal Article] Synthesis and Characterization of Hydroxyethylamino- and Pyridyl-Substituted 2-Vinyl Chromone Derivatives for Detection of Cerebral Abnormal Prion Protein Deposits2022
- Author(s)
  Nakaie Mari、Katayama Fumihiro、Nakagaki Takehiro、Kawasaki Masao、Yoshida Sakura、Toriba Akira、Ogawa Kazuma、Nishida Noriyuki、Nakayama Morio、Fuchigami Takeshi
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 70 Issue: 3 Pages: 211-219
- DOI
  10.1248/cpb.c21-00902
- NAID
  130008165517
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2022-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-21K07276, KAKENHI-PROJECT-21K19452
[Journal Article] Synthesis and Biological Evaluation of Novel 2-(Benzofuran-2-yl)-chromone Derivatives for In Vivo Imaging of Prion Deposits in the Brain2022
- Author(s)
  Nakaie Mari、Katayama Fumihiro、Nakagaki Takehiro、Yoshida Sakura、Kawasaki Masao、Nishi Kodai、Ogawa Kazuma、Toriba Akira、Nishida Noriyuki、Nakayama Morio、Fuchigami Takeshi
- Journal Title
  
  ACS Infectious Diseases
  
  Volume: 8 Issue: 9 Pages: 1869-1882
- DOI
  10.1021/acsinfecdis.2c00142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07276, KAKENHI-PROJECT-21K19452, KAKENHI-PROJECT-23K21396, KAKENHI-PROJECT-23K24276
[Journal Article] Development of α-Synuclein Real-Time Quaking-Induced Conversion as a Diagnostic Method for α-Synucleinopathies2021
- Author(s)
  Nakagaki Takehiro、Nishida Noriyuki、Satoh Katsuya
- Journal Title
  
  Frontiers in Aging Neuroscience
  
  Volume: 13 Pages: 703984-703984
- DOI
  10.3389/fnagi.2021.703984
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-21K07276, KAKENHI-PROJECT-23K21396
[Journal Article] Liquid-liquid phase separation of full-length prion protein initiates conformational conversion in vitro2021
- Author(s)
  Hiroya Tange, Daisuke Ishibashi, Takehiro Nakagaki, Yuzuru Taguchi, Yuji O Kamatari, Hiroki Ozawa, Noriyuki Nishida
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 296 Pages: 100367-100367
- DOI
  10.1016/j.jbc.2021.100367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-20K06390, KAKENHI-PROJECT-21K07276, KAKENHI-PROJECT-20H04285, KAKENHI-PROJECT-23K21396
[Journal Article] Formalin RT-QuIC assay detects prion-seeding activity in formalin-fixed brain samples from sporadic Creutzfeldt?Jakob disease patients2021
- Author(s)
  Dong Thi-Thu-Trang、Akagi Akio、Nonaka Toshiaki、Nakagaki Takehiro、Mihara Ban、Takao Masaki、Iwasaki Yasushi、Nishida Noriyuki、Satoh Katsuya
- Journal Title
  
  Neurobiology of Disease
  
  Volume: 159 Pages: 105504-105504
- DOI
  10.1016/j.nbd.2021.105504
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-18K06506, KAKENHI-PROJECT-21K07276, KAKENHI-PROJECT-21K07417, KAKENHI-PROJECT-20K16183, KAKENHI-PROJECT-23K21396
[Journal Article] Biomarkers and diagnostic guidelines for sporadic Creutzfeldt-Jakob disease2021
- Author(s)
  Hermann Peter、Appleby Brian、Brandel Jean-Philippe、Caughey Byron、Collins Steven、Geschwind Michael D、Green Alison、Haik Stephane、Kovacs Gabor G、Ladogana Anna、Llorens Franc、Mead Simon、Nishida Noriyuki、Pal Suvankar、Parchi Piero、Pocchiari Maurizio、Satoh Katsuya、Zanusso Gianluigi、Zerr Inga
- Journal Title
  
  The Lancet Neurology
  
  Volume: 20 Issue: 3 Pages: 235-246
- DOI
  10.1016/s1474-4422(20)30477-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-17K09759, KAKENHI-PROJECT-21K07417, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-23K21396
[Journal Article] Lead Optimization of Influenza Virus RNA Polymerase Inhibitors Targeting PA-PB1 Interaction2021
- Author(s)
  Mizuta Satoshi、Otaki Hiroki、Ishikawa Takeshi、Makau Juliann Nzembi、Yamaguchi Tomoko、Fujimoto Takuya、Takakura Nobuyuki、Sakauchi Nobuki、Kitamura Shuji、Nono Hikaru、Nishi Ryota、Tanaka Yoshimasa、Takeda Kohsuke、Nishida Noriyuki、Watanabe Ken
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 65 Issue: 1 Pages: 369-385
- DOI
  10.1021/acs.jmedchem.1c01527
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-19K11769, KAKENHI-PROJECT-20K07032, KAKENHI-PROJECT-21K07704, KAKENHI-PROJECT-21K12129, KAKENHI-PROJECT-19K16058, KAKENHI-PROJECT-20H04285, KAKENHI-PROJECT-23K21396
[Journal Article] Dextran sulphate inhibits an association of prions with plasma membrane at the early phase of infection2021
- Author(s)
  Takayuki Fuse, Takehiro Nakagaki, Takujiro Homma, Hiroya Tange, Naohiro Yamaguchi, Ryuichiro Atarashi, Daisuke Ishibashi, Noriyuki Nishida
- Journal Title
  
  Neuroscience research
  
  Volume: S0168-0102(21) Pages: 00018-3
- DOI
  10.1016/j.neures.2021.01.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-21K07276, KAKENHI-PROJECT-20H04285, KAKENHI-PROJECT-23K21396
[Journal Article] Abnormal prion protein deposits with high seeding activities in the skeletal muscle, femoral nerve, and scalp of an autopsied case of sporadic Creutzfeldt?Jakob disease2021
- Author(s)
  Honda Hiroyuki、Mori Shinichiro、Watanabe Akihiro、Sasagasako Naokazu、Sadashima Shoko、??ng Trang、Satoh Katsuya、Nishida Noriyuki、Iwaki Toru
- Journal Title
  
  Neuropathology
  
  Volume: 41 Issue: 2 Pages: 152-158
- DOI
  10.1111/neup.12717
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-17K09759, KAKENHI-PROJECT-23K21396
[Journal Article] Novel Compounds Identified by Structure-Based Prion Disease Drug Discovery Using In Silico Screening Delay the Progression of an Illness in Prion-Infected Mice2020
- Author(s)
  Daisuke Ishibashi, Takeshi Ishikawa, Satoshi Mizuta, Hiroya Tange, Takehiro Nakagaki, Tsuyoshi Hamada, Noriyuki Nishida
- Journal Title
  
  Neurotherapeutics
  
  Volume: 17(4) Issue: 4 Pages: 1836-1849
- DOI
  10.1007/s13311-020-00903-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-18K11536, KAKENHI-PROJECT-20H04285
[Journal Article] Difference in driver gene expression patterns between perihilar and peripheral intrahepatic cholangiocarcinoma in an experimental mouse model2020
- Author(s)
  Adachi Toshiyuki、Adachi Tomohiko、Nakagaki Takehiro、Ono Shinichiro、Hidaka Masaaki、Ito Shinichiro、Kanetaka Kengo、Takatsuki Mitsuhisa、Nishida Noriyuki、Eguchi Susumu
- Journal Title
  
  Journal of Hepato-Biliary-Pancreatic Sciences
  
  Volume: 27 Issue: 8 Pages: 477-486
- DOI
  10.1002/jhbp.772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22600
[Journal Article] Discrimination between L-type and C-type bovine spongiform encephalopathy by the strain-specific reactions of real-time quaking-induced conversion2020
- Author(s)
  Ubagai Kaori、Fukuda Shigeo、Mori Tsuyoshi、Takatsuki Hanae、Taguchi Yuzuru、Kageyama Soichi、Nishida Noriyuki、Atarashi Ryuichiro
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 526 Issue: 4 Pages: 1049-1053
- DOI
  10.1016/j.bbrc.2020.03.183
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10022, KAKENHI-PROJECT-20K07807, KAKENHI-PROJECT-19K22600
[Journal Article] Generation, optimization and characterization of novel anti-prion compounds2020
- Author(s)
  Andrea Altieri, Evgeny A Spiridonov, Semen I Sivtzev, Daisuke Ishibashi, Silvia Biggi, Noriyuki Nishida, Emiliano Biasini, Alexander V Kurkin
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 28(21) Issue: 21 Pages: 115717-115717
- DOI
  10.1016/j.bmc.2020.115717
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-20H04285
[Journal Article] Feasibility studies of radioiodinated pyridyl benzofuran derivatives as potential SPECT imaging agents for prion deposits in the brain2020
- Author(s)
  Fuchigami Takeshi、Kawasaki Masao、Watanabe Hiroyuki、Nakagaki Takehiro、Nishi Kodai、Sano Kazunori、Atarashi Ryuichiro、Nakaie Mari、Yoshida Sakura、Ono Masahiro、Nishida Noriyuki、Nakayama Morio
- Journal Title
  
  Nuclear Medicine and Biology
  
  Volume: 90-91 Pages: 41-48
- DOI
  10.1016/j.nucmedbio.2020.09.003
- NAID
  120006988511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-18K07756
[Journal Article] Administration of FK506 from Late Stage of Disease Prolongs Survival of Human Prion-Inoculated Mice2020
- Author(s)
  Takehiro Nakagaki, Daisuke Ishibashi, Tsuyoshi Mori, Yukiko Miyazaki, Hanae Takatsuki, Hiroya Tange, Yuzuru Taguchi, Katsuya Satoh, Ryuichiro Atarashi, Noriyuki Nishida
- Journal Title
  
  Neurotherapeutics
  
  Volume: 17(4) Issue: 4 Pages: 1850-1860
- DOI
  10.1007/s13311-020-00870-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07844, KAKENHI-PROJECT-20K07807, KAKENHI-PROJECT-19K22600, KAKENHI-PROJECT-17K09759, KAKENHI-PROJECT-20H04285
[Journal Article] Conformational properties of prion strains can be transmitted to recombinant prion protein fibrils in real-time quaking-induced conversion.2014
- Author(s)
  Sano K, Atarashi R, Ishibashi D, Nakagaki T, Satoh K, Nishida N.
- Journal Title
  
  J Virol
  
  Volume: 88(20) Issue: 20 Pages: 11791-11801
- DOI
  10.1128/jvi.00585-14
- NAID
  120006986372
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23300127, KAKENHI-PROJECT-24591268, KAKENHI-PROJECT-24591482, KAKENHI-PROJECT-25461514, KAKENHI-PROJECT-25640029, KAKENHI-PROJECT-26305030, KAKENHI-PROJECT-26860671
[Journal Article] Persistent prion infection disturbs the function of Oct-1, resulting in the down-regulation of murine interferon regulatory factor-3.2014
- Author(s)
  Homma T, Ishibashi D, Nakagaki T, Fuse T, Sano K, Satoh K, Atarashi R, Nishida N.
- Journal Title
  
  Sci Rep
  
  Volume: 4 Issue: 1 Pages: 6006-6006
- DOI
  10.1038/srep06006
- NAID
  120006986450
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23300127, KAKENHI-PROJECT-24591268, KAKENHI-PROJECT-24591482, KAKENHI-PROJECT-25461514, KAKENHI-PROJECT-25640029, KAKENHI-PROJECT-26305030, KAKENHI-PROJECT-26860671
[Journal Article] Increased expression of p62/SQSTM1 in prion diseases and its association with2014
- Author(s)
  Homma T, Ishibashi D, Nakagaki T, Satoh K, Sano K, Atarashi R, Nishida N.
- Journal Title
  
  Sci Rep.
  
  Volume: 4 Issue: 1 Pages: 4504-4504
- DOI
  10.1038/srep04504
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23300127, KAKENHI-PROJECT-24591268, KAKENHI-PROJECT-24591482, KAKENHI-PROJECT-25461514, KAKENHI-PROJECT-26305030
[Journal Article] Pressure-assisted dissociation and degradation of "proteinase K-resistant" fibrils prepared by seeding with scrapie-infected hamster prion protein.2014
- Author(s)
  Akasaka K, Maeno A, Murayama T, Tachibana H, Fujita Y, Yamanaka H, Nishida N, Atarashi R.
- Journal Title
  
  Prion
  
  Volume: 8(4) Issue: 4 Pages: 314-318
- DOI
  10.4161/pri.32081
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23300127, KAKENHI-PROJECT-24570180, KAKENHI-PROJECT-25450444, KAKENHI-PROJECT-25640029
[Journal Article] FK506reduces abnormal prion protein through the activation of autolysosomal degradation and prolongs survival in prion-infected mice.2013
- Author(s)
  Nakagaki T, Satoh K, Ishibashi D, Fuse T, Sano K, Kamatari YO, Kuwata K, Shigematsu K, Iwamaru Y, Takenouchi T, Kitani H, Nishida N, Atarashi R.
- Journal Title
  
  Autophagy.
  
  Volume: 9 Issue: 9 Pages: 1386-1394
- DOI
  10.4161/auto.25381
- NAID
  120006986076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300127, KAKENHI-PROJECT-23370068, KAKENHI-PROJECT-24570180, KAKENHI-PROJECT-24591482, KAKENHI-PROJECT-25461514
[Journal Article] Protective role of interferon regulatory factor3-mediated signaling against prion infection2012
- Author(s)
  Ishibashi D, Atarashi R, Fuse T, Nakagaki T, Yamaguchi N, Satoh K, Honda K, Nishida N
- Journal Title
  
  J Virol
  
  Volume: (Epub ahead of print)
- NAID
  120006985559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300127
[Journal Article] Protective role of MyD88 independent innate immune responses against prion infection.2012
- Author(s)
  Ishibashi D, Atarashi R, Nishida N
- Journal Title
  
  Prion
  
  Volume: 6(5) Issue: 5 Pages: 43-446
- DOI
  10.4161/pri.22579
- NAID
  120006985798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300127, KAKENHI-PROJECT-24591482
[Journal Article] Real-time quaking-induced conversion : A highly sensitive assay for prion detection2011
- Author(s)
  Atarashi R, Sano K, Satoh K, Nishida N
- Journal Title
  
  Prion
  
  Volume: 5(3) Pages: 150-153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300127
[Journal Article] Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion.2011
- Author(s)
  Atarashi R, Satoh K, Sano K, Fuse T, Yamaguchi N, Ishibashi D, Matsubara T, Nakagaki T, Yamanaka H, Shirabe S, Yamada M, Mizusawa H, Kitamoto T, Klug G, McGlade A, Collins SJ, Nishida N.
- Journal Title
  
  Nature medicine 17(2)
  
  Pages: 175-178
- NAID
  120006984771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591002
[Journal Article] High sensitivity of an ELISA kit for detection of the gamma-isoform of 14-3-3 proteins : usefulness in laboratory diagnosis of human prion disease2011
- Author(s)
  Matsui Y, Satoh K, Miyazaki T, Shirabe S, Atarashi R, Mutsukura K, Satoh A, Kataoka Y, Nishida N
- Journal Title
  
  BMC Neurol
  
  Volume: 11 Pages: 120-120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300127
[Journal Article] Transcytosis of murine-adapted bovine spongiform encephalopathy agents in an in vitro bovine M cell model.2010
- Author(s)
  Miyazawa K, Kanaya T, Takakura I, Tanaka S, Hondo T, Watanabe H, Rose MT, Kitazawa H, Yamaguchi T, Katamine S, Nishida N, Aso H.
- Journal Title
  
  J Virol 84(23)
  
  Pages: 12285-12291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591002
[Journal Article] Development of an Ultra-Rapid Diagnostic Method Based on Heart-Type Fatty Acid Binding Protein Levels in the CSF of CJD Patients.2010
- Author(s)
  Matsui Y, Satoh K, Mutsukura K, Watanabe T, Nishida N, Matsuda H, Sugino M, Shirabe S, Eguchi K, Kataoka Y
- Journal Title
  
  Cell Mol Neurobiol 30(7)
  
  Pages: 991-999
- NAID
  120006984526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591002
[Journal Article] Establishment of a standard 14-3-3 protein assay of cerebrospinal fluid as a diagnostic tool for Creutzfeldt-Jakob disease.2010
- Author(s)
  Satoh K, Tobiume M, Matsui Y, Mutsukura K, Nishida N, Shiga Y, Eguhchi K, Shirabe S, Sata T.
- Journal Title
  
  Lab Invest 90(11)
  
  Pages: 1637-1644
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591002
[Journal Article] Hyperefficient PrP Sc amplification of mouse-adapted BSE and scrapie strain by protein misfolding cyclic amplification technique2009
- Author(s)
  Fujihara A, Atarashi R, Fuse T, Ubagai K, Nakagaki T, Yamaguchi N, Ishibashi D, Katamine S, Nishida N
- Journal Title
  
  FEBS J. 276(10)
  
  Pages: 2841-2848
- NAID
  120006984475
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591002
[Journal Article] Bone marrow stroma cells are susceptible to prion infection.2008
- Author(s)
  Takakura Y, Yamaguchi N, Nakagaki T, Satoh K, Kira J, Nishida N
- Journal Title
  
  Biochem Biophys Res Commun 377(3)
  
  Pages: 957-961
- NAID
  120006984617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591002
[Journal Article] Hot spots in prion protein for pathogenic conversion2007
- Author(s)
  KuwataK, NishidaN, MatsumotoT, KamatariO.Y, MutoH.J, Kodama K, Nakamura K.H.Kimura K, KawasakiM, TakakuraY, ShirabeS, TakataJ, KataokaY, KatamineS
- Journal Title
  
  ProcNatlAcadSci USA104(29)
  
  Pages: 11921-11926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590999
[Journal Article] プリオン株をめぐる謎「特集・プリオン病とBSE」2006
- Author(s)
  西田教行
- Journal Title
  
  化学療法の領域 22巻1号
  
  Pages: 71-80
- Data Source
  KAKENHI-PROJECT-16209017
[Journal Article] Prion strain-dependent differences in conversion of mutant prion proteins in cell culture.2006
- Author(s)
  Atarashi R, Sim VL, Nishida N, Caughey B, Katamine S
- Journal Title
  
  J Virol 80 (16)
  
  Pages: 7854-7862
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209017
[Journal Article] Reciprocal interference between specific CJD and scrapie agents in neural cell cultures.2005
- Author(s)
  Nishida N et al.
- Journal Title
  
  Science 21(5747)
  
  Pages: 493-496
- Data Source
  KAKENHI-PROJECT-16209017
[Patent] 経皮吸収型貼付剤2022
- Inventor(s)
  中垣岳大、後藤雅宏、西田教行、佐藤克也、小坂秀斗
- Industrial Property Rights Holder
  中垣岳大、後藤雅宏、西田教行、佐藤克也、小坂秀斗
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-23K21396
[Presentation] 高感度プリオン検出系「RT-QuIC法」を用いた解剖ご遺体のスクリーニング2023
- Author(s)
  西田教行
- Organizer
  第128回日本解剖学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21396
[Presentation] 虚血性脳疾患(脳梗塞)の間葉系幹細胞移植治療2017
- Author(s)
  堀江信貴、西田教行、佐藤克也、松尾孝之
- Organizer
  第122回日本解剖学会総会
- Place of Presentation
  長崎大学医学部(長崎県・長崎市)
- Year and Date
  2017-03-29
- Invited
- Data Source
  KAKENHI-PROJECT-26462165
[Presentation] RT-QUIC法を用いたヒトプリオンサンプル中のSeeding Activityの測定2012
- Author(s)
  高月英恵、新竜一郎、佐野和憲、佐藤克也、西田教行
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23300127
[Presentation] アミロイドイメージングプローブとしてのクロモン誘導体の評価2012
- Author(s)
  山下有紀, 小川綾華, 祖母井香織, 淵上剛志, 原武衛, 小野正博, 佐野和憲, 新竜一郎, 西田教行, 中山守雄
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-21390348
[Presentation] アミロイドイメージングプローブとしてのスチリルクロモン誘導体の評価2011
- Author(s)
  小川綾華, 渡邊裕之, 小野正博, 新竜一郎, 西田教行, 小橋信弥, 瀧口徹, 淵上剛志, 原武衛, 中山守雄
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21390348
[Presentation] アミロイドイメージングプローブとしてのスチリルクロモン誘導体の評価2011
- Author(s)
  小川綾華, 渡邊裕之, 小野正博, 新竜一郎, 西田教行, 山下有紀, 淵上剛志, 原武衛, 中山守雄
- Organizer
  第51回日本核医学会学術総会
- Place of Presentation
  つくば
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-21390348
[Presentation] Establishment of Standardization of 14-3-3 protein assay as a Diagnostic Tool in Creutzfeldt-Jakob disease patients' CSF2008
- Author(s)
  Katsuya Satoh, Minoru Tobiume, Yuki Matsui, Kazuo Mutsukura Noriyuki Nishida, Yusei Shiga, Katsumi Eguhchi, Susunm Shirabe, Testutaro. Sata
- Organizer
  NeuroPrion
- Place of Presentation
  Spain
- Data Source
  KAKENHI-PROJECT-19590999
[Presentation] プリオン感染腎特異的遺伝子発現とヒトプリオン病での意義2007
- Author(s)
  佐藤克也重松和人,西田教行,調漸,江口勝美
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  愛知
- Data Source
  KAKENHI-PROJECT-19590999
[Presentation] Conformational properties of prion strains can be transmitted to recombinant prion protein fibrils in real-time quaking-induced conversion.
- Author(s)
  Sano K, Atarashi R, Nishida N
- Organizer
  Prion2014
- Place of Presentation
  Trieste, Italy
- Year and Date
  2014-05-27 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-23300127
[Presentation] 異常型プリオンタンパク試験管内増幅法（Real-time QUIC法）によるプリオン株鑑別診断法の開発と分子機構の解明
- Author(s)
  新竜一郎, 祖母井香織, 福田茂夫，西田教行
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜（パシフィコ横浜）
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-23300127
[Presentation] プリオン蛋白の構造安定性に対する金属イオンの影響
- Author(s)
  祖母井香織, 新竜一郎, 西田教行
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23300127

1. SATOH Katsuya (70398147)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
2. KATAMINE Shigeru (40161062)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. KUWATA Kazuo (00170142)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SHIRABE Susumu (40264220)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. FUSE Takayuki (30432975)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. HORIE Nobutaka (70380912)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. 日宇健 (00404260)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. 山口将 (70712131)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. NAKAYAMA Morio (60164373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. HARATAKE Mamoru (40325668)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. ARANO Yasushi (90151167)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. ISHIHARA Jyun (80250413)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. ATARASHI Ryuichiro (90452846)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
14. NIWA Masami (20136641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. YAMASHITA Yasuko (80291532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KATAAKA Yasufumi (70136513)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ITO Takasi (90306275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. FURUKAWA Hisako (80341452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 定方英作 (10772139)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 出雲剛 (40343347)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 諸藤陽一 (40437869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 石橋大輔 (10432973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
23. 中垣岳大 (80722917)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
24. 松尾孝之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 森剛志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 水田賢志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 大滝大樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NISHIDA Noriyuki 西田 教行

Nishida Noriyuki 西田 教行

西田 教之 ニシダ ノリユキ

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プリオン病発症に関わるミクログリア制御機構の解明Principal Investigator

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Replication of sCJD in vtroPrincipal Investigator

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[Journal Article] Challenges Based on Antiplasmodial and Antiviral Activities of 7‐Chloro‐4‐aminoquinoline Derivatives2023

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[Journal Article] Stem Cell Therapy for Acute/Subacute Ischemic Stroke with a Focus on Intraarterial Stem Cell Transplantation: From Basic Research to Clinical Trials2022

Author(s)

NISHIDA Noriyuki 西田教行

Nishida Noriyuki 西田教行

西田教之ニシダノリユキ