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Yoshiji Hitoshi  吉治 仁志

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YOSHIJI Hitoshi  吉治 仁志

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Researcher Number 40336855
Other IDs
Affiliation (Current) 2025: 奈良県立医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 奈良県立医科大学, 医学部, 教授
2015 – 2019: 奈良県立医科大学, 医学部, 教授
2012 – 2014: 奈良県立医科大学, 医学部, 准教授
2013: 奈良県立医科大学, 医学科, 准教授
2007 – 2011: 奈良県立医科大学, 医学部, 講師
2006 – 2007: 奈良県立医科大学, 医学部, 学内講師
2002 – 2006: 奈良県立医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Gastroenterology / Basic Section 53010:Gastroenterology-related / Gastroenterology
Except Principal Investigator
Gastroenterology / Basic Section 53010:Gastroenterology-related / Basic Section 57080:Social dentistry-related / Medical pharmacy / Gastroenterology
Keywords
Principal Investigator
Angiotensin-II / 肝線維化 / VEGF / 血管新生 / エンドトキシン / 肝癌 / 肝硬変 / 肝臓学 / ヒアルロン酸ミセル / Angiogenesis … More / アンジオテンシン受容体阻害薬 / Gut-Liver axis / 肝星細胞 / ARB / Leaky Gut / 新規マーカー / 腸内細菌 / Hepatocellular Carcinoma / VFGF / Tet system / Angiotensin II / 選択的NOTCH1阻害薬 / 肝前駆細胞 / 肝再生 / カクテル療法 / 慢性肝疾患 / レニンアンジオテンシン系 / インスリン抵抗性 / アンジオテンシン / 肝発癌 … More
Except Principal Investigator
肝線維化 / 非アルコール性脂肪肝炎 / 急性肝不全 / endocytic retrieval / multidrug export pump / canalicular export pump / crosslinker / radixin / 肝癌 / 血管新生 / NASH / ウルソデオキシコール酸 / エンドトキシン / TNF-α / Toll-like受容体 / サルコペニア / バイオマーカー / 急性腎障害 / ACLF / VWF / ADAMTS13 / 内毒素 / 肝硬変 / 残歯数 / 口腔状態 / 歯周病 / 腸肝相関 / equal / 腸内細菌 / equol / エクオール / farnesoid X receptor / FXR / OCT1 / 胆汁酸 / transporter protein / phosphorylation / cholestasis / multidrug resistance protein2 / 輸送蛋白 / リン酸化 / 胆汁うっ滞 / vascularization / tumor suppressor gene / cell cycle / immunity / retrovirus / adenovirus / hepatocellular carcinoma / gene therapy / レトロウイルス / アデノウイルス / 自殺遺伝子 / 癌抑制遺伝子 / 細胞周期 / 免疫 / レトロウィルス / アデノウィルス / 遺伝子治療 / DPPⅣ阻害剤 / DPPIV阻害剤 / PAI-1 / DPP4阻害剤 / PAI-1阻害剤 / SGLT-2阻害剤 / DPP-Ⅳ阻害剤 / ARB / 生活習慣病 / 難吸収性抗菌薬 / 腸管相関 / 自然免疫 / Kupffer 細胞 / Toll-like 受容体 / ガラクトサミン / TLR4アンタゴニスト / アルコール性肝障害 / Toll-like受容体(TLR)4 / Kupffer細胞 / 非アルコール性脂肪肝炎(NASH) / マクロファージ Less
  • Research Projects

    (18 results)
  • Research Products

    (272 results)
  • Co-Researchers

    (30 People)
  •  A new strategy for the treatment of cirrhotic sarcopenia using a combination of exercise therapy and ADAMTS13 replacement therapy.

    • Principal Investigator
      浪崎 正
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Nara Medical University
  •  Development of Simultaneous Control Therapy for Complications of Cirrhosis Using Enhanced Drug RepositioningPrincipal Investigator

    • Principal Investigator
      吉治 仁志
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Nara Medical University
  •  血液凝固制御因子ADAMTS13による急性肝不全新規治療法とバイオマーカーの開発

    • Principal Investigator
      高谷 広章
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Nara Medical University
  •  Novel Liver Cirrhosis Treatment by Drug Repositioning and Leaky Gut ControlPrincipal Investigator

    • Principal Investigator
      Yoshiji Hitoshi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Nara Medical University
  •  歯周病と慢性肝疾患病態の関連解明-新たな肝疾患進展予防施策の探索

    • Principal Investigator
      赤羽 たけみ
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      Nara Medical University
  •  Development of therapeutic method to suppress liver disease progression by drug repositioningPrincipal Investigator

    • Principal Investigator
      Yoshiji Hitoshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nara Medical University
  •  Therapeutic effect of Equol on gut microbiome - mediated NASH progression

    • Principal Investigator
      NOGUCHI RYUICHI
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nara Medical University
  •  Identification of novel treatment and biomarkers based on pharmacokinetics in patients with hepatocellular carcinoma

    • Principal Investigator
      Namisaki Tadashi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Nara Medical University
  •  Development of new therapeutic approaches against chronic liver diseases with combination of hepatic progenitor cells and clinical available agentsPrincipal Investigator

    • Principal Investigator
      Yoshiji Hitoshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nara Medical University
  •  Establishment of new treatment targeting lifestyle diseases and coagulation fibrinolytic system related to the development of NASH

    • Principal Investigator
      Noguchi Ryuichi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nara Medical University
  •  Establishment of new therapy for chronic liver diseases progressionPrincipal Investigator

    • Principal Investigator
      YOSHIJI Hitoshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nara Medical University
  •  Gut-liver axis mediated by endotoxin and innate immunity

    • Principal Investigator
      FUKUI HIROSHI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nara Medical University
  •  Crosstalk of renin-angiotensin system in the chronic liver diseases and therapeutic applicationsPrincipal Investigator

    • Principal Investigator
      YOSHIJI Hitoshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nara Medical University
  •  マクロファージと肝障害:Toll-like受容体制御による新規治療の探索

    • Principal Investigator
      FUKUI Hiroshi, 福井 博
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nara Medical University
  •  Establishment of order-made therapy for liver fibrosis and hepatocellular carcinoma via angiogenesis suppressionPrincipal Investigator

    • Principal Investigator
      YOSHIJI Hitoshi
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nara Medical University
  •  Role of radixin in cholestasis

    • Principal Investigator
      KOJIMA Hideyuki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nara Medical University
  •  Immunogene therapy for hepatocellular carcinoma : combination with local gene therapy

    • Principal Investigator
      KURIYAMA Shigeki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Kagawa University
      香川大学(医学部)
  •  Mechanistic Investigation and future clinical application of anti-angiogenic theraphy in hepatacellular carcinomaPrincipal Investigator

    • Principal Investigator
      YOSHIJI Hitoshi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nara Medical University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

  • [Book] The Evolving Landscape of Liver Cirrhosis Management2019

    • Author(s)
      Kawaratani H, Yoshiji H
    • Total Pages
      10
    • Publisher
      Springer
    • ISBN
      9789811376634
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Book] 今日の診断指針 第8版2019

    • Author(s)
      吉治仁志
    • Total Pages
      11
    • Publisher
      医学書院
    • ISBN
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Book] Annual Review 2016 消化器2016

    • Author(s)
      野口隆一、吉治仁志
    • Total Pages
      7
    • Publisher
      中外医学
    • Data Source
      KAKENHI-PROJECT-26461018
  • [Book] アルコール性肝障害と炎症性サイトカイン2013

    • Author(s)
      瓦谷英人,辻本達寛,守屋圭,高谷広章,堂原彰敏,美登路昭,吉治仁志,藤本正男,福井博
    • Publisher
      エンドトキシン・自然免疫研究
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Book] 肝硬変合併症の治療 耐糖能異常の病態と治療2013

    • Author(s)
      吉治仁志他
    • Total Pages
      3
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Book] 医学のあゆみ2013

    • Author(s)
      吉治仁志他
    • Total Pages
      6
    • Publisher
      医歯薬出版株式会社
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Book] 消化器病学の進歩-原点から未来への情報発信-(血管新生因子VEGFを標的とした肝癌再発抑制:ACE阻害剤、ビタミンK併用療法の臨床的検討)2009

    • Author(s)
      吉治仁志、野口隆一、福井博
    • Total Pages
      206
    • Publisher
      日本消化器病学会
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Book] 消化器疾患におけるエピゲノミクスとゲノミクス(血管新生因子VEGFに対する既存薬剤を用いた分子標的治療の試み:インスリン抵抗性条件下での肝発癌に対するBCAAの効果)2009

    • Author(s)
      吉治仁志、鍛治孝祐、北出光輝、池中康英、野口隆一、吉井純一、簗瀬公嗣、山崎正晴、浪崎正、福井博
    • Total Pages
      135
    • Publisher
      アークメディア
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Book] 肝胆膵(レニン・アンジオテンシン系阻害薬)2009

    • Author(s)
      吉治仁志、野口隆一、福井博
    • Total Pages
      313
    • Publisher
      アークメディア
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Book] 慢性肝疾患 日本臨床2009

    • Author(s)
      吉治仁志、野口隆一、福井博
    • Total Pages
      799
    • Publisher
      日本臨牀社
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Book] 肝胆膵(血管新生阻害剤の新しい展開「肝癌」)2009

    • Author(s)
      吉治仁志、野口隆一、福井博
    • Total Pages
      307
    • Publisher
      アークメディア
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Book] 肝胆膵(レニンアンジオテンシン系阻害薬による肝線維化抑制)2008

    • Author(s)
      吉治仁志, ほか
    • Total Pages
      313
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Book] New Research on Precancerous Conditions2007

    • Author(s)
      Yoshiji H, et. al.
    • Total Pages
      21
    • Publisher
      Nova Science Publishers Inc(New York)
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590668
  • [Book] 「研究成果報告書概要(和文)」より2007

    • Author(s)
      Yoshiji H, et. al.
    • Total Pages
      21
    • Publisher
      Nova Science Publishers Inc(New York)
    • Data Source
      KAKENHI-PROJECT-17590668
  • [Book] Role of angiogenesis in the development of preneoplastic lesions in hepatocellular carcinoma2007

    • Author(s)
      Yoshiji H, et. al.
    • Total Pages
      640
    • Publisher
      Nova Science Publishers
    • Data Source
      KAKENHI-PROJECT-17590668
  • [Book] Liver Diseases2006

    • Author(s)
      Yoshiji H et al.
    • Total Pages
      540
    • Publisher
      Science Publishers
    • Data Source
      KAKENHI-PROJECT-17590668
  • [Book] New perspectives in Cancer Research and Therapy2005

    • Author(s)
      Yoshiji H et al.
    • Total Pages
      432
    • Publisher
      Research Signpost
    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Blockade of angiotensin II modulates insulin-like growth factor 1-mediated skeletal muscle homeostasis in experimental steatohepatitis2024

    • Author(s)
      Tanaka Misako、Kaji Kosuke、Nishimura Norihisa、Asada Shohei、Koizumi Aritoshi、Matsuda Takuya、Yorioka Nobuyuki、Tsuji Yuki、Fujinaga Yukihisa、Sato Shinya、Namisaki Tadashi、Akahane Takemi、Yoshiji Hitoshi
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

      Volume: 1871 Issue: 2 Pages: 119649-119649

    • DOI

      10.1016/j.bbamcr.2023.119649

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Journal Article] Tofogliflozin Delays Portal Hypertension and Hepatic Fibrosis by Inhibiting Sinusoidal Capillarization in Cirrhotic Rats2024

    • Author(s)
      Asada Shohei、Kaji Kosuke、Nishimura Norihisa、Koizumi Aritoshi、Matsuda Takuya、Tanaka Misako、Yorioka Nobuyuki、Sato Shinya、Kitagawa Koh、Namisaki Tadashi、Akahane Takemi、Yoshiji Hitoshi
    • Journal Title

      Cells

      Volume: 13 Issue: 6 Pages: 538-538

    • DOI

      10.3390/cells13060538

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Journal Article] The Ratio of von Willebrand Factor Antigen to ADAMTS13 Activity: Usefulness as a Prognostic Biomarker in Acute-on-Chronic Liver Failure2023

    • Author(s)
      Takaya Hiroaki、Namisaki Tadashi、Enomoto Masahide、Kubo Takahiro、Tsuji Yuki、Fujinaga Yukihisa、Nishimura Norihisa、Kaji Kosuke、Kawaratani Hideto、Moriya Kei、Akahane Takemi、Matsumoto Masanori、Yoshiji Hitoshi
    • Journal Title

      Biology

      Volume: 12 Issue: 2 Pages: 164-164

    • DOI

      10.3390/biology12020164

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08084
  • [Journal Article] A Combination of an Angiotensin II Receptor and a Neprilysin Inhibitor Attenuates Liver Fibrosis by Preventing Hepatic Stellate Cell Activation2023

    • Author(s)
      Suzuki Junya、Kaji Kosuke、Nishimura Norihisa、Kubo Takahiro、Tomooka Fumimasa、Shibamoto Akihiko、Iwai Satoshi、Tsuji Yuki、Fujinaga Yukihisa、Kitagawa Koh、Namisaki Tadashi、Akahane Takemi、Yoshiji Hitoshi
    • Journal Title

      Biomedicines

      Volume: 11 Issue: 5 Pages: 1295-1295

    • DOI

      10.3390/biomedicines11051295

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Journal Article] Rifaximin enhances the L carnitine mediated preventive effects on skeletal muscle atrophy in cirrhotic rats by modulating the gut liver muscle axis.2022

    • Author(s)
      Murata K, Kaji K, Nishimura N, Enomoto M, Fujimoto Y, Takeda S, Tsuji Y, Fujinaga Y, Takaya H, Kawaratani H, Namisaki T, Akahane T, Yoshiji H
    • Journal Title

      Int J Mol Med.

      Volume: 50 Issue: 2 Pages: 101-101

    • DOI

      10.3892/ijmm.2022.5157

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Journal Article] Leaky Gut and Severe Adverse Events in Advanced Hepatocellular Carcinoma Treated With Lenvatinib.2022

    • Author(s)
      Fujimoto Y, Namisaki T, Takeda S, Murata K, Enomoto M, Takaya H, Tsuji Y, Fujinaga Y, Sawada Y, Nishimura N, Kitagawa K, Kaji K, Inoue T, Kawaratani H, Moriya K, Akahane T, Mitoro A, Yoshiji H.
    • Journal Title

      Anticancer Res

      Volume: 42 Issue: 10 Pages: 4895-4905

    • DOI

      10.21873/anticanres.15995

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Journal Article] Effect of combined farnesoid X receptor agonist and angiotensin II type 1 receptor blocker on ongoing hepatic fibrosis.2022

    • Author(s)
      Namisaki T, Kaji K, Shimozato N, Kaya D, Ozutsumi T, Tsuji Y, Fujinaga Y, Kitagawa K, Furukawa M, Sato S, Sawada Y, Nishimura N, Takaya H, Okura Y, Seki K, Kawaratani H, Moriya K, Noguchi R, Asada K, Akahane T, Mitoro A, Yoshiji H
    • Journal Title

      Indian J Gastroenterol.

      Volume: 41 Issue: 2 Pages: 169-180

    • DOI

      10.1007/s12664-021-01220-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Journal Article] Rifaximin and lubiprostone mitigate liver fibrosis development by repairing gut barrier function in diet-induced rat steatohepatitis.2022

    • Author(s)
      Enomoto M, Kaji K, Nishimura N, Fujimoto Y, Murata K, Takeda S, Tsuji Y, Fujinaga Y, Takaya H, Kawaratani H, Namisaki T, Akahane T, Yoshiji H.
    • Journal Title

      Dig Liver Dis

      Volume: 54 Issue: 10 Pages: 1392-1402

    • DOI

      10.1016/j.dld.2022.04.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Journal Article] Dual therapy with zinc acetate and rifaximin prevents from ethanol-induced liver fibrosis by maintaining intestinal barrier integrity2021

    • Author(s)
      Fujimoto Y, Kaji K, Nishimura N, Enomoto M, Murata K, Takeda S, Takaya H, Kawaratani H, Moriya K, Namisaki T, Akahane T, Yoshiji H.
    • Journal Title

      World J Gastroenterol.

      Volume: 28 Issue: 48 Pages: 8323-8342

    • DOI

      10.3748/wjg.v27.i48.8323

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Journal Article] Sulforaphane ameliorates ethanol plus carbon tetrachloride-induced liver fibrosis in mice through the Nrf2-mediated antioxidant response and acetaldehyde metabolization with inhibition of the LPS/TLR4 signaling pathway2021

    • Author(s)
      Ishida K, Kaji K, Sato S, Ogawa H, Takagi H, Takaya H, Kawaratani H, Moriya K, Namisaki T, Akahane T, Yoshiji H
    • Journal Title

      J Nutr Biochem

      Volume: 89 Pages: 108573-108573

    • DOI

      10.1016/j.jnutbio.2020.108573

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Journal Article] Angiotensin Receptor Blockers Potentiate the Protective Effect of Branched-Chain Amino Acids on Skeletal Muscle Atrophy in Cirrhotic Rats2021

    • Author(s)
      Takeda S, Kaji K, Nishimura N, Enomoto M, Fujimoto Y, Murata K, Takaya H, Kawaratani H, Moriya K, Namisaki T, Akahane T, Yoshiji H
    • Journal Title

      Mol Nutr Food Res

      Volume: 65 Issue: 24

    • DOI

      10.1002/mnfr.202100526

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Journal Article] Rifaximin Alleviates Endotoxemia with Decreased Serum Levels of Soluble CD163 and Mannose Receptor and Partial Modification of Gut Microbiota in Cirrhotic Patients.2020

    • Author(s)
      Kaji K, Saikawa S, Takaya H, Fujinaga Y, Furukawa M, Kitagawa K, Ozutsumi T, Kaya D, Tsuji Y, Sawada Y, Kawaratani H, Moriya K, Namisaki T, Akahane T, Mitoro A, Yoshiji H.
    • Journal Title

      Antibiotics (Basel)

      Volume: 9 Issue: 4 Pages: 145-145

    • DOI

      10.3390/antibiotics9040145

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Journal Article] Gut dysbiosis associated with clinical prognosis of patients with primary biliary cholangitis.2020

    • Author(s)
      Furukawa M, Moriya K, Nakayama J, Inoue T, Momoda R, Kawaratani H, Namisaki T, Sato S, Douhara A, Kaji K, Kitade M, Shimozato N, Sawada Y, Saikawa S, Takaya H, Kitagawa K, Akahane T, Mitoro A, Yamao J, Tanaka Y, Yoshiji H.
    • Journal Title

      Hepatol Res.

      Volume: 4 Issue: 7 Pages: 840-852

    • DOI

      10.1111/hepr.13509

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Journal Article] TGR5 Activation Modulates an Inhibitory Effect on Liver Fibrosis Development Mediated by Anagliptin in Diabetic Rats2019

    • Author(s)
      Kaya Daisuke、Kaji Kosuke、Tsuji Yuki、Yamashita Satoko、Kitagawa Koh、Ozutsumi Takahiro、Fujinaga Yukihisa、Takaya Hiroaki、Kawaratani Hideto、Moriya Kei、Namisaki Tadashi、Akahane Takemi、Yoshiji Hitoshi
    • Journal Title

      Cells

      Volume: 8 Issue: 10 Pages: 1153-1153

    • DOI

      10.3390/cells8101153

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K15824, KAKENHI-PROJECT-17K09438
  • [Journal Article] Combining probiotics and an angiotensin-II type 1 receptor blocker has beneficial effects on hepatic fibrogenesis in a rat model of non-alcoholic steatohepatitis.2019

    • Author(s)
      Sawada Y, Kawaratani H, Kubo T, Fujinaga Y, Furukawa M, Saikawa S, Sato S, Seki K, Takaya H, Okura Y, Kaji K, Shimozato N, Mashitani T, Kitade M, Moriya K, Namisaki T, Akahane T, Mitoro A, Yamao J, Yoshiji H.
    • Journal Title

      Hepatol Res.

      Volume: 49 Issue: 3 Pages: 404-418

    • DOI

      10.1111/hepr.13281

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Journal Article] Late-Evening Snack with Branched-Chain Amino Acid-Enriched Nutrients Does Not Always Inhibit Overt Diabetes in Patients with Cirrhosis: A Pilot Study.2019

    • Author(s)
      Nakanishi K, Namisaki T, Mashitani T, Kaji K, Ozaki K, Saikawa S, Sato S, Inoue T, Sawada Y, Kitagawa K, Takaya H, Shimozato N, Kawaratani H, Moriya K, Akahane T, Mitoro A, Yoshiji H.
    • Journal Title

      Nutrients.

      Volume: 7 Issue: 9 Pages: 2140-2140

    • DOI

      10.3390/nu11092140

    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Journal Article] Sodium glucose cotransporter 2 inhibitor canagliflozin attenuates liver cancer cell growth and angiogenic activity by inhibiting glucose uptake.2018

    • Author(s)
      Kaji K, Nishimura N, Seki K, Sato S, Saikawa S, Nakanishi K, Furukawa M, Kawaratani H, Kitade M, Moriya K, Namisaki T, Yoshiji H.
    • Journal Title

      International Journal of Cancer

      Volume: 142 Issue: 8 Pages: 17121722-17121722

    • DOI

      10.1002/ijc.31193

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Journal Article] Oral administration of fructose exacerbates liver fibrosis and hepatocarcinogenesis via increased intestinal permeability in a rat steatohepatitis model2018

    • Author(s)
      Seki K, Kitade M, Nishimura N, Kaji K, Asada K, Namisaki T, Moriya K, Kawaratani H, Okura Y, Takaya H, Sawada Y, Sato S, Nakanishi K, Yoshiji H.
    • Journal Title

      Oncotarget.

      Volume: 9 Issue: 47 Pages: 28638-51

    • DOI

      10.18632/oncotarget.25587

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Journal Article] Angiotensin receptor blockade attenuates cholangiocarcinoma cell growth by inhibiting the oncogenic activity of Yes-associated protein.2018

    • Author(s)
      Saikawa S, Kaji K, Nishimura N, Seki K, Sato S, Nakanishi K, Kitagawa K, Kawaratani H, Kitade M, Moriya K, Namisaki T, Mitoro A, Yoshiji H.
    • Journal Title

      Cancer Letters

      Volume: 434 Pages: 120-129

    • DOI

      10.1016/j.canlet.2018.07.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Journal Article] von Willebrand factor is a useful biomarker for liver fibrosis and prediction of hepatocellular carcinoma development in patients with hepatitis B and C.2018

    • Author(s)
      Takaya H, Kawaratani H, Tsuji Y, Nakanishi K, Saikawa S, Sato S, Sawada Y, Kaji K, Okura Y, Shimozato N, Kitade M, Akahane T, Moriya K, Namisaki T, Mitoro A, Matsumoto M, Fukui H, Yoshiji H
    • Journal Title

      United European Gastroenterol J.

      Volume: 6 Issue: 9 Pages: 1401-1409

    • DOI

      10.1177/2050640618779660

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09438, KAKENHI-PROJECT-16K10580
  • [Journal Article] Acyclic retinoid and angiotensin-II receptor blocker exert a combined protective effect against diethylnitrosamine-induced hepatocarcinogenesis in diabetic OLETF rats.2018

    • Author(s)
      Nishimura N, Kaji K, Kitade M, Aihara Y, Sato S, Seki K, Sawada Y, Takaya H, Okura Y, Kawaratani H, Moriya K, Namisaki T, Mitoro A, Yoshiji H
    • Journal Title

      BMC Cancer.

      Volume: 18 Issue: 1 Pages: 164-171

    • DOI

      10.1186/s12885-018-5099-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Journal Article] Clinical significance of the Scheuer histological staging system for primary biliary cholangitis in Japanese patients.2017

    • Author(s)
      Namisaki T, Moriya K, Kitade M, Kawaratani H, Takeda K, Okura Y, Takaya H, Nishimura N, Seki K, Kaji K, Sato S, Sawada Y, Yamao J, Mitoro A, Uejima M, Mashitani T, Shimozato N, Nakanishi K, Furukawa M, Saikawa S, Kubo T, Yoshiji H.
    • Journal Title

      Eur J Gastroenterol Hepatol.

      Volume: 29 Pages: 23-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08077
  • [Journal Article] Effect of combined farnesoid X receptor agonist and angiotensin Ⅱtipe 1 receptor blocker on hepatic fibrosis.2017

    • Author(s)
      Namisaki T. Moriya K, Kitade M, Takeda K, Kaji K, Okura Y, Shimozato N. Sato S, Nishimura N, Seki K, Kawaratani H, Takaya H, Sawada Y, Akahane T, Saikawa S, Nakanishi K, Kubo T, Furukawa M, Noguchi R, Asada K, Kitagawa K, Ozutsumi T, Tsuji Y, Kaya H Yoshiji
    • Journal Title

      Hepatol commun.

      Volume: 1 Issue: 9 Pages: 928945-928945

    • DOI

      10.1002/hep4.1104

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09438, KAKENHI-PROJECT-15K08077
  • [Journal Article] Rifaximin ameliorates hepatic encephalopathy and endotoxemia without affecting the gut microbiome diversity.2017

    • Author(s)
      Kaji K, Takaya H, Saikawa S, Furukawa M, Sato S, Kawaratani H, Kitade M, Moriya K, Namisaki T, Akahane T, Mitoro A, Yoshiji H.
    • Journal Title

      World J Gastroenterol.

      Volume: 23 Issue: 47 Pages: 83358366-83358366

    • DOI

      10.3748/wjg.v23.i47.8355

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Journal Article] Clinical significance of the Scheuer histological staging system for primary biliary cholangitis in Japanese patients.2017

    • Author(s)
      Namisaki T, Yoshiji H
    • Journal Title

      Eur J Gastroenterol Hepatol.

      Volume: 29 Pages: 23-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461017
  • [Journal Article] Combined treatment with dipeptidyl peptidase-4 inhibitor (sitagliptin) and angiotensin-II type 1 receptor blocker (losartan) suppresses progression in a non-diabetic rat model of steatohepatitis.2016

    • Author(s)
      Okura Y,Yoshiji H.
    • Journal Title

      Hepatol Res

      Volume: Dec28 Issue: 12 Pages: 1317-1328

    • DOI

      10.1111/hepr.12860

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461017, KAKENHI-PROJECT-26461018, KAKENHI-PROJECT-15K08077
  • [Journal Article] DNA methylation of angiotensin II receptor gene in nonalcoholic steatohepatitis-related liver fibrosis.2016

    • Author(s)
      Asada K, Aihara Y, Takaya H, Noguchi R, Namisaki T, Moriya K, Uejima M, Kitade M, Mashitani T, Takeda K, Kawaratani H, Okura Y, Kaji K, Douhara A, Sawada Y, Nishimura N, Seki K, Mitoro A, Yamao J, Yoshiji H.
    • Journal Title

      World J Hepatol.

      Volume: 8 Issue: 28 Pages: 1194-1194

    • DOI

      10.4254/wjh.v8.i28.1194

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461018
  • [Journal Article] Efficacy of alogliptin in preventing non-alcoholic fatty liver disease progression in patients with type 2 diabetes.2016

    • Author(s)
      Mashitani T Yoshiji H.
    • Journal Title

      Biomed Rep.

      Volume: 4 Pages: 183-187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461017
  • [Journal Article] Beneficial effects of combined ursodeoxycholic acid and angiotensin-II type 1 receptor blocker on hepatic fibrogenesis in a rat model of nonalcoholic steatohepatitis.2016

    • Author(s)
      Namisaki T, Noguchi R, Moriya K, Kitade M, Aihara Y, Douhara A, Nishimura N, Takeda K, Okura Y, Kawaratani H, Takaya H, Seki K, Yoshiji H.
    • Journal Title

      J Gastroenterol.

      Volume: 51 Pages: 162-172

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461018
  • [Journal Article] DNA methylation of angiotensin II receptor gene in nonalcoholic steatohepatitis-related liver fibrosis2016

    • Author(s)
      Asada K, Yoshiji H
    • Journal Title

      World J Hepatol

      Volume: 8 Pages: 1194-1197

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461017
  • [Journal Article] Ipragliflozin, a sodium-glucose cotransporter 2 inhibitor, ameliorates the development of liver fibrosis in diabetic Otsuka Long-Evans Tokushima fatty rats.2016

    • Author(s)
      Nishimura N, Yoshiji H.
    • Journal Title

      J Gastroenterol

      Volume: 12 Pages: 1141-1149

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461017
  • [Journal Article] Ipragliflozin, a sodium-glucose cotransporter 2 inhibitor, ameliorates the development of liver fibrosis in diabetic Otsuka Long-Evans Tokushima fatty rats2016

    • Author(s)
      Nishimura N, Kitade M, Noguchi R, Namisaki T, Moriya K, Takeda K, Okura Y, Aihara Y, Douhara A, Kawaratani H, Asada K, Yoshiji H
    • Journal Title

      J Gastroenterol.

      Volume: Mar 29 Issue: 12 Pages: 1141-1149

    • DOI

      10.1007/s00535-016-1200-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461017
  • [Journal Article] Efficacy of alogliptin in preventing non-alcoholic fatty liver disease progression in patients with type 2 diabetes.2016

    • Author(s)
      Mashitani T, Noguchi R, Okura Y, Namisaki T, Mitoro A, Ishii H, Nakatani T, Kikuchi E, Moriyasu H, Matsumoto M, Sato S, An T, Morita H, Aizawa S, Tokuoka Y, Ishikawa M, Matsumura Y, Ohira H, Kogure A, Noguchi K, Yoshiji H.
    • Journal Title

      Biomed Rep.

      Volume: 4 Pages: 183-187

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461018
  • [Journal Article] Beneficial effects of combined ursodeoxycholic acid and angiotensin-II type 1 receptor blocker on hepatic fibrogenesis in a rat model of nonalcoholic steatohepatitis.2016

    • Author(s)
      Namisaki T, Noguchi R, Moriya K, Kitade M, Aihara Y, Douhara A, Nishimura N, Takeda K, Okura Y, Kawaratani H, Takaya H, Seki K, Yoshiji H
    • Journal Title

      Jounal of Gastroenterology

      Volume: 51 Issue: 2 Pages: 162-72

    • DOI

      10.1007/s00535-015-1104-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08077, KAKENHI-PROJECT-26461017
  • [Journal Article] Ipragliflozin, a sodium-glucose cotransporter 2 inhibitor, ameliorates the development of liver fibrosis in diabetic Otsuka Long-Evans Tokushima fatty rats.2016

    • Author(s)
      Nishimura N, Kitade M, Noguchi R, Namisaki T, Moriya K, Takeda K, Okura Y, Aihara Y, Douhara A, Kawaratani H, Asada K, Yoshiji H.
    • Journal Title

      J Gastroenterol.

      Volume: 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461018
  • [Journal Article] The relationship between hepatic progenitor cell-mediated liver regeneration and non-parenchymal cells.2016

    • Author(s)
      Kitade M, Kaji K, Yoshiji H
    • Journal Title

      Hepatol Res.

      Volume: Feb 19 Issue: 12 Pages: 1187-1193

    • DOI

      10.1111/hepr.12682

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461017, KAKENHI-PROJECT-26860523
  • [Journal Article] Reduction of endotoxin attenuates liver fibrosis through suppression of hepatic stellate cell activation and remission of intestinal permeability in a rat non-alcoholic steatohepatitis model.2015

    • Author(s)
      Douhara A, Moriya K, Yoshiji H, Noguchi R, Namisaki T, Kitade M, Kaji K, Aihara Y, Nishimura N, Takeda K, Okura Y, Kawaratani H, Fukui H.
    • Journal Title

      Mol Med Rep.

      Volume: 11 Pages: 1693-1700

    • NAID

      40020982272

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461018
  • [Journal Article] Combination of sorafenib and angiotensin-II receptor blocker attenuates preneoplastic lesion development in a non-diabetic rat model of steatohepatitis.2014

    • Author(s)
      Yoshiji H, Noguchi R, Namisaki T, Moriya K, Kitade M, Aihara Y, Douhara A, Kawaratani H, Nishimura N, Fukui H
    • Journal Title

      J Gastroenterol.

      Volume: 49 Issue: 10 Pages: 1421-1429

    • DOI

      10.1007/s00535-013-0906-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461017
  • [Journal Article] Simultaneous blockade of programmed death 1 and vascular endothelial growth factor receptor 2(VEGFR2) induces synergistic anti-tumour effect in vivo2013

    • Author(s)
      Yasuda S, Sho M, Yamato H, Yoshiji H, Wakatsuki K, Nishiwada S, Yagita H, Nakajima Y
    • Journal Title

      Clnical and Exprtimental Immunology

      Volume: 172 Pages: 500-506

    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Direct renin inhibitor, aliskiren, attenuates the progression of non-alcoholic steatohepatitis in the rat model.2013

    • Author(s)
      Aihara Y, Yoshiji H et al
    • Journal Title

      Hepatol Res.

      Volume: 43 Issue: 11 Pages: 1241-1250

    • DOI

      10.1111/hepr.12081

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Direct renin inhibitor, aliskiren, attenuates the progression of non-alcoholic steatohepatitis in the rat model.2013

    • Author(s)
      Aihara Y, Yoshiji H, et al.
    • Journal Title

      Hepatol Res.

      Volume: Jan 29

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Dual blockade of angiotensin-IIand aldosterone suppresses the progression of a non-diabetic rat model of steatohepatitis2013

    • Author(s)
      Noguchi R, Yoshiji H, Ikenaka Y, Kaji K, Aihara Y, Shirai Y, Namisaki T, Kitade M, Douhara A, Moriya K, Fukui H
    • Journal Title

      Hepatology Research

      Volume: 43(7) Pages: 765-774

    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Cross talk between toll-like receptor-4 signaling and angiotensin-II in liver fibrosis development in the rat model of non-alcoholic steatohepatitis2013

    • Author(s)
      Shirai Y, Yoshiji H, Noguchi R, Kaji K, Aihara Y, Douhara A, Moriya K, Namisaki T, Kawaratani H, Fukui H.
    • Journal Title

      J Gastroenterol Hepatol

      Volume: 28 Pages: 723-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Journal Article] High hemoglobin level predicts non-alcoholic fatty liver disease in japanese women2013

    • Author(s)
      Akahane T, Fukui K, Shirai Y, Yoshiji H, Uemura M, Fukui H
    • Journal Title

      Journal of Gastroenterology and Hepatology Research

      Volume: 2(6 Pages: 623-627

    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Dual blockade of angiotensin-IIand aldosterone suppresses the progression of a non-diabetic rat model of steatohepatitis2013

    • Author(s)
      Noguchi R, Yoshiji H et al
    • Journal Title

      Hepatology Research

      Volume: 43 Issue: 7 Pages: 765-774

    • DOI

      10.1111/hepr.12008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] The effect of inflammatory cytokines in alcoholic liver disease. Mediators2013

    • Author(s)
      Kawaratani, H. Tsujimoto, T. Douhara, A. Takaya, H. Moriya, K. Namisaki, T. Noguchi, R. Yoshiji, H. Fujimoto, M. Fukui, H.
    • Journal Title

      Mediators Inflamm

      Volume: 2013 Pages: 495156-495156

    • DOI

      10.1155/2013/495156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Journal Article] アルコール性肝障害と炎症性サイトカイン2013

    • Author(s)
      瓦谷 英人, 辻本 達寛, 守屋 圭, 高谷 広章, 堂原 彰敏, 美登路 昭, 吉治 仁志, 藤本 正男, 福井 博
    • Journal Title

      エンドトキシン・自然免疫研究

      Volume: 16 Pages: 12-15

    • Data Source
      KAKENHI-PROJECT-23590987
  • [Journal Article] Branched-chain amino acids suppress the cumulative recurrence of hepatocellular carcinoma under conditions of insulin-resistance2013

    • Author(s)
      Yoshiji H, Noguchi R, Namisaki T, Moriya K, Kitade M, Aihara Y, Douhara A, Yamao J, Fujimoto M, Toyohara M, Mitoro A, Sawai M, Yoshida M, Morioka C, Uejima M, Uemura M, Fukui H
    • Journal Title

      Oncology Reports

      Volume: 30 Pages: 545-552

    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Cross talk between toll-like receptor-4 signaling and angiotensin-IIin liver fibrosis development in the rat model of non-alcoholic steatohepatitis2013

    • Author(s)
      Shirai Y, Yoshiji H, Noguchi R, Kaji K, Aihara Y, Douhara A, Moriya K, Namisaki T, Kawaratani H, Fukui H
    • Journal Title

      J Gastroenterol Hepatol

      Volume: 28(4) Pages: 723-30

    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] The effect of inflammatory cytokines in alcoholic liver disease2013

    • Author(s)
      Kawaratani H, Tsujimoto T, Douhara A, Takaya H, Moriya K, Namisaki T, Noguchi R, Yoshiji H, Fujimoto M, Fukui H.
    • Journal Title

      Mediators Inflamm.

      Volume: 2013 Pages: 495156-495156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Journal Article] Dipeptidyl peptidase-4 inhibitor attenuates hepatic fibrosis via suppression of activated hepatic stellate cell in rats2013

    • Author(s)
      Kaji K, Yoshiji H et al
    • Journal Title

      J Gastroenterol.

      Volume: 49 Issue: 3 Pages: 481-491

    • DOI

      10.1007/s00535-013-0783-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Combination of branched-chain amino acid and angiotensin-converting enzyme inhibitor improves liver fibrosis progression in patients with cirrhosis.2012

    • Author(s)
      Yoshiji H, et al
    • Journal Title

      Mol Med Report

      Volume: 5 Pages: 539-544

    • DOI

      10.3892/mmr.2011.676

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Dual blockade of angiotensin-II and aldosterone suppresses the progression of a non-diabetic rat model of steatohepatitis.2012

    • Author(s)
      Noguchi R, Yoshiji H, et al.
    • Journal Title

      Hepatol Res.

      Volume: Nov 20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Possible involvement of angiogenesis in chronic liver diseases : Interaction among renin-angiotensin-aldosterone system, Insulin resistance and oxidative stress2012

    • Author(s)
      Yoshiji H, Ikenaka Y, Noguchi R, Aihara Y, Shirai Y, Douhara A, Fukui H, Kaji K
    • Journal Title

      Current Medicinal Chemistry

      Volume: 19(12) Pages: 1889-1898

    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Combination of branched-chain amino acid and angiotensin-converting enzyme inhibitor improves liver fibrosis progression in patients with cirrhosis.2012

    • Author(s)
      Yoshiji H, et al.
    • Journal Title

      Molecular Medicine Reports

      Volume: 5 Pages: 539-544

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Combination of branched-chain amino acid and angiotensin-converting enzyme inhibitor improves liver fibrosis progression in patients with cirrhosis2012

    • Author(s)
      Yoshiji H, Noguchi R, Ikenaka Y, Kaji K, Aihara Y, Douhara A, Yamao J, Toyohara M, Mitoro A, Sawai M, Yoshida M, Morioka C, Fujimoto M, Uemura M, Fukui H
    • Journal Title

      Molecular Medicine Reports

      Volume: 5 Pages: 539-544

    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Impact of Renin-angiotensin system in hepatocellular carcinoma2011

    • Author(s)
      Yoshiji H, Noguchi R, Ikenaka Y, Kaji K, Aihara Y, Fukui H
    • Journal Title

      Current Cancer Drug Targets

      Volume: 11(4) Pages: 431-441

    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Combination treatment of angiotensinIItypeIreceptor blocker and new oral iron chelator attenuates progression of nonalcoholic steatohepatitis in rats2011

    • Author(s)
      Kaji K, Yoshiji H, Kitade M, Ikenaka Y, Noguchi R, Shirai Y, Aihara Y, Namisaki T, Yoshii J, Yanase K, Tsujimoto T, Kawaratani H, Fukui H
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol

      Volume: 300 Pages: 1094-1104

    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Cocktail therapy with a combination of interferon, ribavirin and angiotensin-II type 1 receptor blocker attenuates murine liver fibrosis development.2011

    • Author(s)
      Yoshiji H, Noguchi R, Ikenaka Y, Kaji K, Aihara Y, Shirai Y, Yoshii J, Yanase K, Fukui H.
    • Journal Title

      Int J Mol Med.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Combination of branched-chain amino acids and angiotensin-converting enzyme inhibitor suppresses the cumulative recurrence of hepatocellular carcinoma: a randomized control trial.2011

    • Author(s)
      Yoshiji H, et al
    • Journal Title

      Oncol Rep

      Volume: 26 Pages: 1547-1553

    • DOI

      10.3892/or.2011.1433

    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Cocktail therapy with a combination of interferon, ribavirin and angiotensin-II type 1 receptor blocker attenuates murine liver fibrosis development.2011

    • Author(s)
      Yoshiji H, et al
    • Journal Title

      Int J Mol Med

      Volume: 28 Pages: 81-88

    • DOI

      10.3892/ijmm.2011.658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Soluble VEGF receptor-2 may be a predictive marker of anti-angiogenic therapy with clinically available safe agents2011

    • Author(s)
      Yoshiji H, Noguchi R, Ikenaka Y, Kaji K, Shirai Y, Aihara Y, Yamao J, Toyohara M, Mitoro A, Sawai M, Yoshida M, Morioka C, Fujimoto M, Uemura M, Kawaratani H, Tsujimoto T, Fukui H
    • Journal Title

      Oncology Letters

      Volume: 2 Pages: 69-73

    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Soluble VEGF receptor-2 may be a predictive marker of anti-angiogenic therapy with clinically available safe agents2011

    • Author(s)
      Yoshiji, H., et al
    • Journal Title

      Oncology Lett

      Volume: 2 Pages: 69-73

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Combination Treatment of Angiotensin-II Type I Receptor Blocker and New Oral Iron Chelator Attenuates Progression of Non-alcoholic Steatohepatitis in Rats.2011

    • Author(s)
      Kaji K, Yoshiji H, et al
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol.

      Volume: Mar 3(In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Cocktail therapy with a combination of interferon, ribavirin and angiotensin-IItype 1 receptor blocker attenuates murine liver fibrosis development2011

    • Author(s)
      Yoshiji H, Noguchi R, Ikenaka Y, Kaji K, Aihara Y, Shirai Y, Yoshiji H, Yanase K, Fukui H
    • Journal Title

      International Journal of Molecular Medicine

      Volume: 28 Pages: 81-88

    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Combination Treatment of Angiotensin-II Type I Receptor Blocker and New Oral Iron Chelator Attenuates Progression of Non-alcoholic Steatohepatitis in Rats.2011

    • Author(s)
      Kaji K, Yoshiji H, Kitade M, Ikenaka Y, Noguchi R, Shirai Y, Aihara Y, Namisaki T, Yoshii J, Yanase K, Tsujimoto T, Kawaratani H, Fukui H.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Impact of Renin-Angiotensin System in Hepatocellular Carcinoma.2011

    • Author(s)
      Yoshiji H, Noguchi R, Ikenaka Y, Kaji K, Aihara Y, Fukui H.
    • Journal Title

      Curr Cancer Drug Targets.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Rapid detection of spotaneous bacterial peritonitis by granulocyte elastase latex immunoassay and reagent strip2011

    • Author(s)
      Yamazaki M, Sano R, Kuramoto C, Yoshiji H, Uemura M, Fukui H, Kamiya M, Okamoto Y
    • Journal Title

      Rinsho Byori

      Volume: 59(6) Pages: 549-558

    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Therapeutic effects of cytokine modulator Y-40138 in the rat alcoholic liver disease model2011

    • Author(s)
      Kawaratani H, Tsujimoto T, Kitazawa T, Yoshiji H, Uemura M, Fukui H
    • Journal Title

      Journal of Gastroenterology and Hepatology

      Volume: 26 Pages: 775-783

    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Combination of branched-chain amino acids and angiotensin-converting enzyme inhibitor suppresses the cumulative recurrence of hepatocellular carcinoma : A randomized control trial2011

    • Author(s)
      Yoshiji H, Noguchi R, Ikenaka Y, Kaji K, Aihara Y, Shirai Y, Yoshiji H, Yanase K, Fukui H
    • Journal Title

      Oncology Reports

      Volume: 26 Pages: 1547-1553

    • Data Source
      KAKENHI-PROJECT-23590986
  • [Journal Article] Attenuation of insulin-resistance-based hepatocarcinogenesis and angiogenesis by combined treatment with branched-chain amino acids and angiotensin-converting enzyme inhibitor in obese diabetic rats.2010

    • Author(s)
      Yoshiji H, Noguchi R, Kaji K, Ikenaka Y, Shirai Y, Namisaki T, Kitade M, Tsujimoto T, Kawaratani H, Fukui H.
    • Journal Title

      J Gastroenterol. 45(4)

      Pages: 443-450

    • NAID

      10027215751

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] J Angiogenes Res.2010

    • Author(s)
      Namisaki T, Yoshiji H, Noguchi R, Ikenaka Y, Kitade M, Kaji K, Shirai Y, Aihara Y, Yoshii J, Yanase K, Tsujimoto T, Kawaratani H, Fukui H.
    • Journal Title

      2 16

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Selective aldosterone blocker ameliorates the progression of non-alcoholic steatohepatitis in rats.2010

    • Author(s)
      Noguchi R, Yoshiji H, Ikenaka Y, Kaji K, Shirai Y, Aihara Y, Yamazaki M, Namisaki T, Kitade M, Yoshii J, Yanase K, Kawaratani H, Tsujimoto T, Fukui H.
    • Journal Title

      Int J Mol Med. 26(3)

      Pages: 407-413

    • NAID

      120006669562

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Selective aldosterone blocker, eplerenone, attenuates hepatocellular carcinoma growth and angiogenesis in mice.2010

    • Author(s)
      Kaji K, Yoshiji H, Kitade M, Ikenaka Y, Noguchi R, Shirai Y, Yoshii J, Yanase K, Namisaki T, Yamazaki M, Tsujimoto T, Kawaratani H, Fukui H.
    • Journal Title

      Hepatol Res. 40(5)

      Pages: 540-549

    • NAID

      10026392261

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Attenuation of insulin-resistance-based hepatocarcinogenesis and angiogenesis by combined treatment with branched-chain amino acids and angiotensin-converting enzyme inhibitor in obese diabetic rats.2010

    • Author(s)
      Yoshiji, H., et al
    • Journal Title

      J Gastroenterol

      Volume: 45 Pages: 443-450

    • NAID

      10027215751

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Attenuation of insulin-resistance-based hepatocarcinogenesis and angiogenesis by combined treatment with branched-chain amino acids and angioten sin-converting enzyme inhibitor in obese diabetic rats2010

    • Author(s)
      Yoshiji, H., et al
    • Journal Title

      J Gastroenterol (In press)

    • NAID

      10027215751

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Combination of vitamin K2 and angiotensin-converting enzyme inhibitor ameliorates cumulative recurrence of hepatocellular carcinoma2009

    • Author(s)
      Yoshiji, H., et al
    • Journal Title

      J Hepatol 51

      Pages: 315-321

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Immunotherapy for nonalcoholic steatohepatitis using the multiple cytokine production modulator Y-40138.2009

    • Author(s)
      Tsujimoto T, Kawaratani H, Kitazawa T, Yoshiji H, Fujimoto M, Uemura M, Fukui H.
    • Journal Title

      World J Gastroenterol 15

      Pages: 5533-40

    • Data Source
      KAKENHI-PROJECT-19590784
  • [Journal Article] Combination of vitamin K2 and angiotensin-converting enzyme inhibitor ameliorates cumulative recurrence of hepatocellular carcinoma.2009

    • Author(s)
      Yoshiji H, Noguchi R, Toyohara M, Ikenaka Y, Kitade M, Kaji K, Yamazaki M, Yamao J, Mitoro A, Sawai M, Yoshida M, Fujimoto M, Tsujimoto T, Kawaratani H, Uemura M, Fukui H.
    • Journal Title

      J Hepatol. 51(2)

      Pages: 315-321

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Crosstalk between angiogenesis, cytokeratin-18, and insulin resistance in the progression of non-alcoholic steatohepatitis.2009

    • Author(s)
      Kitade M, Yoshiji H, Noguchi R, Ikenaka Y, Kaji K, Shirai Y, Yamazaki M, Uemura M, Yamao J, Fujimoto M, Mitoro A, Toyohara M, Sawai M, Yoshida M, Morioka C, Tsujimoto T, Kawaratani H, Fukui H.
    • Journal Title

      World J Gastroenterol. 15(41)

      Pages: 5193-5199

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Branched-chain amino acids suppress insulin-resistance-based hepatocarcin ogenesis in obese diabetic rats2009

    • Author(s)
      Yoshiji, H., et al
    • Journal Title

      J Gastroenterol 44

      Pages: 483-491

    • NAID

      10025175098

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Synergistic inhibitory effect of gemcitabine and angiotensin typel receptor blocker, losartan, on murine pancreatic tumor growth via anti-angiogenic activities2009

    • Author(s)
      Yoshiji H, et al
    • Journal Title

      International Journal of Oncology. (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Branched-chain amino acids suppress insulin-resistance-based hepatocarcinogenesis in obese diabetic rats.2009

    • Author(s)
      Yoshiji H, Noguchi R, Kitade M, Kaji K, Ikenaka Y, Namisaki T, Yoshii J, Yanase K, Yamazaki M, Tsujimoto T, Akahane T, Kawaratani H, Uemura M, Fukui H.
    • Journal Title

      J Gastroenterol. 44(5)

      Pages: 483-491

    • NAID

      10025175098

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Losartan, an angiotensin-II type 1 receptor blocker, attenuates the liver fibrosis development of non-alcoholic steatohepatitis in the rat.2009

    • Author(s)
      Yoshiji H, Noguchi R, Ikenaka Y, Namisaki T, Kitade M, Kaji K, Shirai Y, Yoshii J, Yanase K, Yamazaki M, Tsujimoto T, Kawaratani H, Akahane T, Aihara Y, Fukui H.
    • Journal Title

      BMC Res Notes. 2

      Pages: 70-70

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Synergistic inhibitory effect of gemcitabine and angiotensin type-1 receptor blocker, losartan, on murine pancreatic tumor growth via anti-angiogenic activities.2009

    • Author(s)
      Noguchi R, Yoshiji H, Ikenaka Y, Namisaki T, Kitade M, Kaji K, Yoshii J, Yanase K, Yamazaki M, Tsujimoto T, Kawaratani H, Fukui H.
    • Journal Title

      Oncol Rep. 22(2)

      Pages: 355-360

    • NAID

      120006669561

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Anti-fibrotic therapy: Are matrix metalloproteinases friends or foes?2009

    • Author(s)
      Yoshiji H.
    • Journal Title

      Hepatol Res. 39(8)

      Pages: 748-750

    • NAID

      10025326969

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Combination of vitamin K2 and angiotensin-converting enzyme inhibitor ameliorates cummlative recurrence of hepatocellular carcinoma2009

    • Author(s)
      Yoshiji H, et al
    • Journal Title

      Journal of Hepatology (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Decreased phagocytic activity of Kupffer cells in a rat nonalcoholic steatohepatitis model.2008

    • Author(s)
      Tsujimoto T, Kawaratani H, Kitazawa T, Hirai T, Ohishi H, Kitade M, Yoshiji H, Uemura M, Fukui H
    • Journal Title

      World J Gastroenterol 14

      Pages: 6036-43

    • Data Source
      KAKENHI-PROJECT-19590784
  • [Journal Article] Impact of insulin resistance on the progression of chronic liver diseases.2008

    • Author(s)
      Kaji K, Yoshiji H, Kitade M, Ikenaka Y, Noguchi R, Yoshii J, Yanase K, Namisaki T, Yamazaki M, Moriya K, Tsujimoto T, Kawaratani H, Akahane T, Uemura M, Fukui H.
    • Journal Title

      Int J Mol Med. (6)

      Pages: 801-808

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Different tumoricidal effects of interferon subclasses and p53 status on hepatocellular carcinoma development and neovascularization.2008

    • Author(s)
      Noguchi R, Yoshiji H, et. al.
    • Journal Title

      Int J Oncol 32

      Pages: 193-199

    • NAID

      120004973986

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Innate immune reactivity of the liver in rats fed a choline-deficient L-amino-acid-defined diet.2008

    • Author(s)
      Kawaratani H, Tsujimoto T, Kitazawa T, Kitade M, Yoshiji H, Uemura M, Fukui H
    • Journal Title

      World J Gastroenterol 14

      Pages: 6655-61

    • Data Source
      KAKENHI-PROJECT-19590784
  • [Journal Article] Impact of insulin resistance on the progression of chronic liver diseases.2008

    • Author(s)
      Kaji K, Yoshiji H, et al
    • Journal Title

      Int J Mol Med 193

      Pages: 193-99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Journal Article] Crosstalk between high-molecular-weight adiponectin and T-cadherin during liver fibrosis development in rats.2007

    • Author(s)
      Asada K, Yoshiji H, et. al.
    • Journal Title

      Int J Mol Med 20

      Pages: 725-729

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Renin-angiotensin system inhibitors as therapeutic alternatives in the treatment of chronic liver diseases.2007

    • Author(s)
      Yoshiji H, et. al.
    • Journal Title

      Curr Med Chem 14

      Pages: 2749-2754

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Synergistic inhibition of hepatocellular carcinoma growth and hepatocarcinogenesis by combination of 5-fluorouracil and angiotensin-converting enzyme inhibitor via anti-angiogenic activities.2007

    • Author(s)
      Yanase K, Yoshiji H, et. al.
    • Journal Title

      Oncol Rep 17

      Pages: 441-446

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Combined treatment of vitamin K2 and angiotensin-converting enzymeinhibitor ameliorates hepatic dysplastic nodule in a patient with liver cirrhosis.2007

    • Author(s)
      Yoshiji H, et. al.
    • Journal Title

      World J Gastroenterol 13

      Pages: 3259-3261

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Blockade of renin-angiotensin system in antifibrotic therapy.2007

    • Author(s)
      Yoshiji H, et. al.
    • Journal Title

      J Gastroenterol Hepatol 22

      Pages: 93-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Leptin-mediated neovascularization is a prerequisite for progression of nonalcoholic steatohepatitis2006

    • Author(s)
      Kitade M, Yoshiji H et al.
    • Journal Title

      Hepatology 44

      Pages: 983-991

    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Angiotensin-II and vascular endothelial growth factor interaction plays an important role in rat liver fibrosis development2006

    • Author(s)
      Yoshiji H et al.
    • Journal Title

      Hepatology Research 36

      Pages: 124-129

    • NAID

      10018640620

    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Amelioration of carcinogenesis and tumor growth in the rat liver by combination of vitamin K2 and angiotensin-converting enzyme inhibitor via anti-angiogenic activities2006

    • Author(s)
      Yoshiji H et al.
    • Journal Title

      Oncology Reports 15

      Pages: 155-159

    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Salvage effect of the vascular endothelial growth factor on chemically induced acute severe liver injury in rats2006

    • Author(s)
      Namisaki T, Yoshiji H et al.
    • Journal Title

      Journal of Hepatology 44

      Pages: 568-575

    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Amelioration of liver fibrogenesis by dual inhibition of PDGF and TGF-beta with a combination of imatinib mesylate and ACE inhibitor in rats2006

    • Author(s)
      Yoshiji H et al.
    • Journal Title

      International Molecular Medicine 17

      Pages: 899-904

    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Leptin mediated neovascularization is a prerequisite for progression of nonalcoholic steatohepatitis in rats2006

    • Author(s)
      Kitade M., Yoshiji H, et. al.
    • Journal Title

      Hepatology 44

      Pages: 983-991

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Leptin-mediated neovascularization is a prerequisite for progression of nonalcoholic steatohepatitis in rats2006

    • Author(s)
      Kitade, M., Yoshiji H, et. al.
    • Journal Title

      Hepatology 44

      Pages: 983-991

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Interferon augments the anti-fibrotic activity of an angiotensin-converting enzyme inhibitor in patients with refractory chronic hepatitis C2006

    • Author(s)
      Yoshiji H et al.
    • Journal Title

      World Journal of Gastroenterology 12

      Pages: 6786-6791

    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Combined effect of an ACE inhibitor, perindopril, and interferon on liver fibrosis markers in patients with chronic hepatitis C2005

    • Author(s)
      Yoshiji H et al.
    • Journal Title

      Journal of Gastroenterology 40

      Pages: 215-216

    • NAID

      10014513843

    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Angiopoietin 2 displays a vascular endothelial growth factor dependent synergistic effect in hepatocellular carcinoma development in mice2005

    • Author(s)
      Yoshiji H, et. al.
    • Journal Title

      GUT 54

      Pages: 1768-1775

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Suppression of rennin-angiotensin system attenuates hepatocarcinogenesis via angiogenesis suppression2005

    • Author(s)
      Yoshiji H et al.
    • Journal Title

      Anti Cancer Research 25

      Pages: 3335-3340

    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Adenovirus-mediated gene transfer into rat livers : Comparative study of retrograde intrabiliary and antegrade intraportal administration.2005

    • Author(s)
      Kuriyama S, Yoshiji H
    • Journal Title

      Oncol Rep 13

      Pages: 69-74

    • Data Source
      KAKENHI-PROJECT-14370185
  • [Journal Article] Combination of vitamin K2 and the angiotensin-converting enzyme inhibitor, perindopril, attenuates the liver enzyme-altered preneoplastic lesions in rats via angiogenesis suppression2005

    • Author(s)
      Yoshiji H, et. al.
    • Journal Title

      Journal of Hepatology 42

      Pages: 687-693

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Combination of interferon and angiotensin-converting enzymeinhibitor ; perindopril, suppresses liver carcinogenesis and angiogenesis in mice2005

    • Author(s)
      Yoshiji H et al.
    • Journal Title

      Oncology Reports 13

      Pages: 491-495

    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Adenovirus-mediated gene transfer into rat livers : Comparative study of retrograde intrabiliary and antegrade intraportal administration.2005

    • Author(s)
      Kuriyama S, Yoshiji H, 11 others
    • Journal Title

      Oncol Rep 13

      Pages: 69-74

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370185
  • [Journal Article] Different cascades in the signaling pathway of two vascular endothelial growth factor (VEGF) receptors for the VEGF-mediated murine2005

    • Author(s)
      Yoshiji H et al.
    • Journal Title

      Oncology Reports 13

      Pages: 853-857

    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Adenovirus-mediated gene transfer into rat livers : Comparative study of retrograde intrabiliary and antegrade intraportal administration.2005

    • Author(s)
      Kuriyama S, Yoshiji H, 11others
    • Journal Title

      Oncol Rep 13

      Pages: 69-74

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370185
  • [Journal Article] Angiopoietin-2 displays a vascular endothelial growth factor dependent synergistic effect in hepatocellular carcinoma development in mice2005

    • Author(s)
      Yoshiji H et al.
    • Journal Title

      GUT 54

      Pages: 1768-1775

    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Combination of vitamin K2 and the angiotensin converting enzyme inhibitor,perindopril,attenuates the liver enzyme altered preneoplastic lesions in rats via angiogenesis suppression2005

    • Author(s)
      Yoshiji H, et. al.
    • Journal Title

      J Hepatol 42

      Pages: 687-693

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Combination of vitamin K2 and angiotension-vonverting enzyme inhibitor ; perindopril, attenuates the liver enzyme-altered preneoplastic lesions2005

    • Author(s)
      Yoshiji H et al.
    • Journal Title

      Journal of Hepatology 42

      Pages: 687-693

    • Data Source
      KAKENHI-PROJECT-17590668
  • [Journal Article] Halting the interaction between vascular endothelial growth factor and its receptors attenuates liver carcinogenesis in mice.2004

    • Author(s)
      Yoshiji H, Kuriyama S, 12 others
    • Journal Title

      Hepatology 39

      Pages: 1517-1524

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370185
  • [Journal Article] Involvement of the vascular endothelial growth factor receptor-1 in murine hepatocellular carcinoma development.2004

    • Author(s)
      Yoshiji H, Kuriyama S, 10 others
    • Journal Title

      J Hepatol 41

      Pages: 97-103

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370185
  • [Journal Article] Angiotensin-I converting enzyme inhibitors as potential anti-angiogenic agents for cancer therapy.2004

    • Author(s)
      Yoshiji H, Kuriyama S, 2 others
    • Journal Title

      Current Cancer Drug Targets 4

      Pages: 555-567

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370185
  • [Journal Article] Role of radixin in altered localization of canalicular conjugate export pump mrp2 in cholestatic rat liver

    • Author(s)
      Kojima H, Sakurai S, Yoshiji H, Uemura M, Yoshikawa M, Fukui H.
    • Journal Title

      Hepatol Res. (in print)

    • NAID

      10020170150

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590669
  • [Journal Article] Role of radixin in altered localization of canalicular conjugate export pump mrp2 in cholestatic rat liver.

    • Author(s)
      Kojima H, Sakurai S, Yoshiji H, Uemura M, Yoshikawa M, Fukui H.
    • Journal Title

      Hepatol Res. (in print)

    • NAID

      10020170150

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590669
  • [Patent] [台 湾出願] 1061101802017

    • Inventor(s)
      浪崎 正、吉治 仁志
    • Industrial Property Rights Holder
      大日本住友製薬株式会社
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017-03-27
    • Overseas
    • Data Source
      KAKENHI-PROJECT-15K08077
  • [Patent] [PCT出願] PCT/JP2017/0124482017

    • Inventor(s)
      浪崎 正、吉治 仁志
    • Industrial Property Rights Holder
      大日本住友製薬株式会社
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017-03-27
    • Overseas
    • Data Source
      KAKENHI-PROJECT-15K08077
  • [Presentation] Glucagon-like Peptide-1 Receptor Agonist, Semaglutide Attenuates Chronic Liver Disease-induced Skeletal Muscle Atrophy in Diabetic Mice2023

    • Author(s)
      Iwai S, Kaji K, Nishimura N, Kubo T, Tomooka F, Shibamoto A, Suzuki J, Tsuji Y, Fujinaga Y, Kitagawa K, Namisaki T, Akahane T, Yoshiji H
    • Organizer
      APASL
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Presentation] Vitamin D Deficiency Exacerbates Alcohol-related Liver Injury via Gut Barrier Disruptionand Hepatic Overload of Endotoxin2023

    • Author(s)
      Shibamoto A, Kaji K, Yoshiji H
    • Organizer
      APASL
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Presentation] Dual Angiotensin II Receptor and Neprilysin Inhibitor Attenuates Liver Fibrosis by Preventing Hepatic Stellate Cell Activation2023

    • Author(s)
      Suzuki J, Kaji K, Nishimura N, Kubo T, Tomooka F, Shibamoto A, Iwai S, Tsuji Y, Fujinaga Y, Kitagawa K, Namisaki T, Akahane T, Yoshiji H
    • Organizer
      APASL
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Presentation] ARB potentiate the Protective Effect of BCAA on Skeletal Muscle Atrophy in Cirrhotic Rats2022

    • Author(s)
      Takeda S, Kaji K, Yoshiji H
    • Organizer
      日本肝臓学会大会 JDDW2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Presentation] アルコール性肝障害モデルマウスを用いた、酢酸亜鉛とリファキシミン併用療法による肝繊維化予防効果の検討2022

    • Author(s)
      藤本優樹、鍛治孝祐、吉治仁志
    • Organizer
      日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Presentation] Rifaximin/L-carnitine 併用による肝硬変ラット骨格筋委縮に対する予防効果2022

    • Author(s)
      村田晃児、鍛治孝祐、高谷広章、瓦谷英人、守屋圭、浪崎正、赤羽たけみ、美登路昭、吉治仁志
    • Organizer
      日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Presentation] ACLFにおけるADAMTS13の動態2022

    • Author(s)
      高谷広章, 浪崎正, 鍛治孝祐, 西村典久, 吉治仁志
    • Organizer
      第48回日本急性肝不全研究会
    • Data Source
      KAKENHI-PROJECT-22K08084
  • [Presentation] アルコール肝障害モデルマウスを用いた酢酸亜鉛とリファキシミン併用療法による肝繊維化予防効果の検討2022

    • Author(s)
      藤本優樹、鍛治孝祐、、吉治仁志
    • Organizer
      日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Presentation] 肝硬変ラット骨格筋委縮に対するRifaximin/L/carnitine 併用療法の効果2022

    • Author(s)
      村田晃児、鍛治孝祐、吉治仁志
    • Organizer
      日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Presentation] Lubiprosone と Rifaximin 併用による gut-liver axis 制御とNASH肝繊維化抑制効果2022

    • Author(s)
      榎本壮秀、鍛治孝祐、吉治仁志
    • Organizer
      日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Presentation] Rifaximin および L-carnitine併用による肝硬変ラット骨格筋委縮に対する予防効果の検討2022

    • Author(s)
      村田晃児、鍛治孝祐、吉治仁志
    • Organizer
      日本門脈圧亢進症学会総会
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Presentation] LPSにより肝星細胞から産生される epiregulin の肝癌進展における役割とその作用機序2022

    • Author(s)
      久保貴裕、鍛治孝祐、吉治仁志
    • Organizer
      日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-21K08013
  • [Presentation] ACLFにおけるADAMTS13の動態2022

    • Author(s)
      高谷広章, 浪﨑正, 吉治仁志
    • Organizer
      JDDW2022
    • Data Source
      KAKENHI-PROJECT-22K08084
  • [Presentation] Effect of ARB and Rifaximin combination therapy on hepatic fibrosis in nonalcoholic steatohepatitis model rats2019

    • Author(s)
      Fujinaga Y, Kawaratani H, Namisaki T, Moriya K, kaji K, Takaya H, Sawada Y, Akahane T, Sato S, Shimozato N, Saikawa S, Nakanishi K, Kubo T, Furukawa M, Yoshiji H
    • Organizer
      AASLD
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Presentation] The potential effect of combination therapies with a farnesoid X receptor(FXR)agonist on hepatic fibrogenesis in rat nash model2019

    • Author(s)
      Shimozato N, Namisaki T, Kaji K, Takaya H, Saikawa S, Sawada Y, Nakanishi K, Furukawa M, Fujinaga Y, Kaya D, Tsuji Y, Kawaratani H, Akahane T, Yoshiji H
    • Organizer
      AASLD
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Presentation] Exogenous administration of low-dose lipopolysaccharide potentiates the development of liver fibrosis in a choline-deficient L-amino-acide-defined diet-induced murine steatohepatitis model2019

    • Author(s)
      Nakanishi K, Kaya D, Tsuji Y, Saikawa S, Kaji K, Akahane T, Namisaki T, Yoshiji H
    • Organizer
      AASLD
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Presentation] Gut-Liver axis を標的としたNASH治療戦略2019

    • Author(s)
      中西啓祐、鍛治 孝祐、吉治 仁志
    • Organizer
      日本肝臓学会大会
    • Data Source
      KAKENHI-PROJECT-17K09439
  • [Presentation] Rifaximin ameliorates hepatic encephalopathy and endotoxemia without affecting the gut microbiome diversity2019

    • Author(s)
      Takaya H, Kaji K, Saikawa S, Furukawa M, Sato S, Sawada Y, Kawaratani H, Kitade M, Moriya K, Namisaki T, Akahane T, Mitoro A, Yoshiji H
    • Organizer
      EASL
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Presentation] Combined treatment with anti-diabetic agents:dipeptidyl peptidase-4 inhibitor(DPP4-1) and sodiumglucose co-transporter-2 inhibitor(SGLT2-1) suppresses progression in nash rat model2019

    • Author(s)
      Namisaki T, Ozutsumi T, Kaji K, Shimozato N, Saikawa S, Takaya H, Nakanishi K, Tsuji Y, Sawada Y, Furukawa M, Fujinaga Y, Kaya D, Kawaratani H, Akahane T, Yoshiji H
    • Organizer
      AASLD
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Presentation] Biochemical response to ursodeoxycholic acid predicts histologic primary biliary cholangitis progression2018

    • Author(s)
      Fujinaga Y, Namisaki T, Moriya K, Kitade M, Kawaratani H, Kaji K, Okura Y, Seki K, Takaya H, Sawada Y, Akahane T, Nishimura N, Sato S, Shimozato N, Saikawa S, Nakanishi K, Kubo T, Furukawa M, Yoshiji H
    • Organizer
      AASLD
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08077
  • [Presentation] Rifaximin ameliorates hepatic encephalopathy and endotoxemia without affecting the gut microbiome diversity2018

    • Author(s)
      Takaya H, Kaji K, Saikawa S, Furukawa M, Sato S, Sawada Y, Kawaratani H, Kitade M, Moriya K, Namisaki T, Akahane T, Mitoro A, Yoshiji H
    • Organizer
      EASL
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Presentation] Moderate alcohol consumption protects against fatty liver in males2018

    • Author(s)
      Akahane T, Namisaki T, Kitade M, Kaji K, Takaya H, Shimozato N, Sato S, Yoshiji H
    • Organizer
      EASL
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Presentation] Identification of von willebrand factor-to-ADAMTS13 ratio as a potential biomarker for early detection of hepatocellular carcinoma in patients with liver cirrhosis2018

    • Author(s)
      Takaya H, Namisaki T, Kaji K, Kitade M, Tsuji Y, Fujinaga Y, Furukawa M, Nakanishi K, Seki K, Sato S, Sawada Y, Saikawa S, Shimozato N, Kawaratani H, Asada K, Moriya K, Akahane T, Yoshiji H
    • Organizer
      AASLD
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Presentation] Effect of nalfurafine hydrochloride for refractory pruritus in patients with primary biliary cholangitis: a multicenter, postmarketing single-arm, prospective study2018

    • Author(s)
      Yagi M, Tanaka A, Namisaki T, Abe M, Takahashi A, Honda A, Matsuzaki Y, Ohira H, Yoshiji H, Takikawa H
    • Organizer
      EASL
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08077
  • [Presentation] Ratio of Von Willebrand Factor to ADAMTS13 is a Novel Potential Biomarker for Early Diagnosis of HCC2018

    • Author(s)
      Takaya H, Namisaki T, Kitade M, Kaji K, Shimozato N, Akahane T, Moriya K, Kawaratani H, Sawada Y, Seki K, Sato S, Nakanishi K, Yoshiji H
    • Organizer
      APASL
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Presentation] Rifaximin alleviates endotoxemia with improvement of intestinal hyperpermeability and minor changes in fecal microbiota in cirrohotic patients with hepatic encephalopathy2018

    • Author(s)
      Kaji K, Saikawa S, Takaya H, Sato S, Kitade M, Moriya K, Namisaki T, Akahane T, Yoshiji H
    • Organizer
      AASLD
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Presentation] Beneficial effects of combined farnesoid X receptor agonist(INT747) and dipeptidyl peptidase-4 inhibitor(sitagliptin) on hepatic fibrogenesis in a rat model of nonalcoholic steatohepatitis2017

    • Author(s)
      Shimozato N, Namisaki T, Moriya K, Kitade M, Takeda K, Kawaratani H, Kaji K, Okura Y, Takaya H, Sawada Y, Nishimura N, Sato S, Saikawa S, Seki K, Furukawa M, Nakanishi K, Kubo T, Yoshiji H
    • Organizer
      AASLD
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Presentation] ADAMTS13 deficiency exacerbates acute liver failure with enhanced VWF accumulation and hepatic inflammation in mice.2017

    • Author(s)
      Takaya H, Kaji K, Kitade M, Seki K, Saikawa S, Nishimura N, Sato S, Sawada Y, Okura Y, Kawaratani H, Akahane T, Moriya K, Namisaki T, Mitoro A, Yoshiji H
    • Organizer
      AASLD
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09438
  • [Presentation] Pruritus, dryness, fatigue and health-related quality of life in Japanese patients with primaty biliaty cholangitis2017

    • Author(s)
      Yagi M, Tanaka A, Abe M, Namisaki T, Yoshiji H, Takahashi A, Ohira H, Komori A, Yamagiwa S, and et al.
    • Organizer
      AASLD
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08077
  • [Presentation] Bezafibrate improves GLOBE and UK-PBC scores and long-term outcomes in patients with primary biliary cholangitis2017

    • Author(s)
      Honda A, Tanak A, Komori A, Abe M, Inao M, Moshida S, Namisaki T, Yoshiji H, Hashimoto N, Kawata K, Takahashi A, Ohira H, and et al.
    • Organizer
      AASLD
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08077
  • [Presentation] Beneficial effects of combined farnesoid X receptor agonist(INT747) and dipeptidyl peptidase-4 inhibitor(sitagliptin) on hepatic fibrogenesis in a rat model of nonalcoholic steatohepatitis2017

    • Author(s)
      Shimozato N, Namisaki T, Moriya K, Kitade M, Takeda K, Kawaratani H, Kaji K, Okura Y, Takaya H, Sawada Y, Nishimura N, Sato S, Saikawa S, Seki K, Furukawa M, Nakanishi K, Kubo T, Yoshiji H
    • Organizer
      AASLD
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08077
  • [Presentation] DNMT1-deleted hepatocytes cause promoted replicative senescence and induce liver fibrosis development with global DNA hypomethylation.2016

    • Author(s)
      Kaji K, Yoshiji H;
    • Organizer
      AASLD
    • Place of Presentation
      ボストン米国
    • Year and Date
      2016-11-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461017
  • [Presentation] Antifirotic effects of combined treatment with farnesoid X receptor agonist and angiotensin-Ⅱtype1 receptor blocker on hepatic fibrogenesis in the rat model of nonalcoholic steatohepatitis.2016

    • Author(s)
      Namisaki T, Yoshiji H
    • Organizer
      EASL
    • Place of Presentation
      バルセロナ スペイン
    • Year and Date
      2016-04-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461017
  • [Presentation] DPP4阻害薬及びアンギオテンシンⅡ受容体拮抗薬併用による肝病態進展抑制効果2016

    • Author(s)
      大倉康志、浪崎正、野口隆一、守屋圭、北出光輝、竹田幸祐、瓦谷英人、相原洋祐、西村典久、佐藤慎哉、澤田保彦、関建一郎、増谷剛、鍛治孝祐、吉治仁志
    • Organizer
      日本消化器病学会総会
    • Place of Presentation
      東京
    • Year and Date
      2016-04-21
    • Data Source
      KAKENHI-PROJECT-26461017
  • [Presentation] Impact of the combination of dipeptidyl peptidase IV inhibitor and angiotensin-Ⅱtype 1 receptor blocker on hepatocarcinogenesis in a rat model of nonalcoholic steatohepatitis.2016

    • Author(s)
      Okura Y, Yoshiji H;
    • Organizer
      EASL
    • Place of Presentation
      バルセロナ スペイン
    • Year and Date
      2016-04-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461017
  • [Presentation] DPP4阻害薬及びアンギオテンシンII受容体拮抗薬併用による肝病態進展抑制効2016

    • Author(s)
      大倉康志、浪崎正、野口隆一、守屋圭、北出光輝、竹田幸祐、瓦谷英人、相原洋祐、西村典久、佐藤慎哉、澤田保彦、関建一郎、増谷剛、鍛冶孝佑、吉治仁志
    • Organizer
      第102回日本消化器病学会総会
    • Place of Presentation
      京王プラザホテル
    • Year and Date
      2016-04-22
    • Data Source
      KAKENHI-PROJECT-26461018
  • [Presentation] Impact of the combination of dipeptidyl peptidase IV inhibitor and angiotensin-Ⅱtype 1 receptor blocker on hepatocarcinogenesis in a rat model of nonalcoholic steatohepatitis2016

    • Author(s)
      Okura Y, Namisaki T, Noguchi R, Takeda K, Moriya K, Kitade M, Nishimura N, Sato S, Sawada Y, Kawaratani H, Seki K, Kaji K, Yoshiji H
    • Organizer
      EASL
    • Place of Presentation
      Spain Barcelona
    • Year and Date
      2016-02-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461017
  • [Presentation] Antifirotic effects of combined treatment with farnesoid X receptor agonist and angiotensin-Ⅱtype1 receptor blocker on hepatic fibrogenesis in the rat model of nonalcoholic steatohepatitis2016

    • Author(s)
      Namisaki T, Okura Y, Sato S, Noguchi R, Moriya K, Kitade M, Takeda K, Nishimura N, Sawada Y, Seki K, Kawaratani H, Kaji K, Yoshiji H
    • Organizer
      EASL
    • Place of Presentation
      Spain Barcelona
    • Year and Date
      2016-02-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461017
  • [Presentation] NASH and general management2016

    • Author(s)
      Yoshiji H
    • Organizer
      EASL
    • Place of Presentation
      Spain Barcelona
    • Year and Date
      2016-02-23
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461017
  • [Presentation] Combination treatment of dipeptidyl peptidase Ⅳ inhibitor and angiotensin-Ⅱtype 1 receptor blocker attenuates progression of nonalcoholic steatohepatitis in rats.2016

    • Author(s)
      Sato S, Yoshiji H;
    • Organizer
      AASLD
    • Place of Presentation
      ボストン米国
    • Year and Date
      2016-11-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461017
  • [Presentation] 糖尿病ラットにおけるSGL T2阻害薬の肝線維化抑制効果と作用機序2016

    • Author(s)
      西村典久、北出光輝、吉治仁志
    • Organizer
      日本消化器病学会総会
    • Place of Presentation
      東京
    • Year and Date
      2016-04-21
    • Data Source
      KAKENHI-PROJECT-26461017
  • [Presentation] Antifibrotic effects of combined treatment with Farnesoid X receptor agonist and angiotensin-II type1 receptor blocker on hepatic fibrogenesis in the rat model of nonalcoholic steatohepatitis2016

    • Author(s)
      Tadashi Namisaki, Yasushi Okura, Shinya Sato, Ryuichi Noguchi, Kei Moriya, Mitsuteru Kitade, Kosuke Takeda, Yosuke Aihara, Norihisa Nishimura, Yasuhiko Sawada, Kenichiro Seki, Hideto Kawaratani, Kosuke Kaji, Hitoshi Yoshiji.
    • Organizer
      ヨーロッパ肝臓学会
    • Place of Presentation
      バルセロナ スペイン
    • Year and Date
      2016-04-13
    • Data Source
      KAKENHI-PROJECT-15K08077
  • [Presentation] mpact of the combination of Farnesoid Ⅹ receptor agonist and angiotensin-Ⅱtype1 receptor blocker on hepatic fibrogenesis in the rat model of nonalcoholic steatohepatitis.2016

    • Author(s)
      Namisaki T, Yoshiji H;
    • Organizer
      AASLD
    • Place of Presentation
      ボストン米国
    • Year and Date
      2016-11-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461017
  • [Presentation] Combination treatment of dipeptidyl peptidase IV inhibitor and angiotensin-II type 1 receptor blocker attenuates progression of nonalcoholic steatohepatitis in rats2016

    • Author(s)
      Shinya Sato, Tadashi Namisaki, Kosuke Kaji, Norihisa Nishimura, Yasushi Okura, Ryuichi Noguchi, Kosuke Takeda, Kei Moriya, Mitsuteru Kitade, Kenichiro Seki, Hiroaki Takaya, Hideto Kawaratani, Yasuhiko Sawada, Naotaka Shimozato, Keisuke Nakanishi, Hitoshi Yoshiji
    • Organizer
      アメリカ肝臓学会
    • Place of Presentation
      ボストン US
    • Year and Date
      2016-11-11
    • Data Source
      KAKENHI-PROJECT-15K08077
  • [Presentation] 糖尿病発症ラットにおける非環式レチノイドとアンギオテンシンII受容体拮抗薬の併用による肝発癌抑制効果2015

    • Author(s)
      西村典久 、北出光輝、野口隆一、吉治仁志
    • Organizer
      第24回日本がん転移学会学術集会総会
    • Place of Presentation
      シティプラザ大阪
    • Year and Date
      2015-07-23
    • Data Source
      KAKENHI-PROJECT-26461018
  • [Presentation] アンギオテンシンII・アルドステロンを標的とする肝癌治療:血管新生の観点から2015

    • Author(s)
      野口隆一、堂原彰敏 、西村典久 、吉治仁志
    • Organizer
      第24回日本がん転移学会学術集会総会
    • Place of Presentation
      シティプラザ大阪
    • Year and Date
      2015-07-23
    • Data Source
      KAKENHI-PROJECT-26461018
  • [Presentation] 非アルコール性脂肪性肝疾患(NAFLD)合併2型糖尿病患者に対するDPP-IV阻害薬による肝線維化抑制の試み2015

    • Author(s)
      増谷剛、野口隆一、吉治仁志
    • Organizer
      第2回肝臓と糖尿病・代謝研究会
    • Place of Presentation
      シーモールパレス
    • Year and Date
      2015-05-23
    • Data Source
      KAKENHI-PROJECT-26461018
  • [Presentation] インスリン抵抗性条件下における DPP4阻害薬とARB併用による新規肝線維化治療の試み2014

    • Author(s)
      野口隆一、吉治仁志、福井 博
    • Organizer
      第50回日本肝臓学会総会
    • Place of Presentation
      ホテルニューオータニ
    • Year and Date
      2014-05-29
    • Data Source
      KAKENHI-PROJECT-26461018
  • [Presentation] 自然免疫制御による肝線維化の抑制:小腸Tight Junction Proteinの役割2014

    • Author(s)
      堂原 彰敏, 吉治 仁志, 福井 博
    • Organizer
      第50回日本肝臓学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Presentation] 自然免疫制御による肝線維化の抑制:小腸Tight Junction Proteinの役割2014

    • Author(s)
      堂原彰敏,吉治仁志,福井博
    • Organizer
      第50回日本肝臓学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Presentation] Beneficial effects of combined treatment with ursodoxycholic acid (UDCA) and Angiotensin-IItype1 receptor blocker(ARB) on liver fibrosis development in the rat model of nonalcoholic steatohepatitis2013

    • Author(s)
      Namisaki T, Yoshiji H, Noguchi R, Moriya K, Kitade M, Aihara Y, Douhara A, Kawaratani H, Nishimura N, Fukui H
    • Organizer
      Annual Meeting of the Japanese Society for the Research of Hepatic Cells
    • Place of Presentation
      Osaka
    • Year and Date
      2013-09-26
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] 内因性エンドトキシン制御による肝線維化抑制作用機序の検討2013

    • Author(s)
      堂原彰敏,吉治仁志,守屋圭,野口隆一,浪崎正,相原洋祐,瓦谷英人,福井博
    • Organizer
      第49回日本肝臓学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Presentation] ウルソデオキシコール酸とアンジオテンシンII受容体阻害薬併用によるNASH線維化進展抑制の試み2013

    • Author(s)
      浪崎 正、吉治仁志、福井 博
    • Organizer
      第49回日本肝臓学会総会(ワークショップ5)
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Presentation] VEGF-targeted cancer therapy : Friends of Foes2013

    • Author(s)
      Yoshiji H
    • Organizer
      National Cancer Institute Special Seminar 2013
    • Place of Presentation
      Washington, DC.
    • Year and Date
      2013-04-10
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] Beneficial effects of combined treatment with ursodoxycholic acid (UDCA) and Angiotensin-IItype1 receptor blocker(ARB) on liver fibrosis development in the rat model of nonalcoholic steatohepatitis2013

    • Author(s)
      Namisaki T, Yoshiji H, Noguchi R, Moriya K, Kitade M, Aihara Y, Douhara A, Kawaratani H, Nishimura N, Fukui H.
    • Organizer
      Annual Meeting of the Japanese Society for the Research of Hepatic Cells
    • Place of Presentation
      大阪
    • Year and Date
      2013-09-26
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Presentation] Response-guided anti-angiogenic therapy for hepatocellular carcinoma recurrence with clinically available safety agent2013

    • Author(s)
      Yoshiji H et al
    • Organizer
      AACR Annual Meeting 2013
    • Place of Presentation
      Washington, DC, USA
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] 肝障害をめぐる腸肝相関 DSS腸炎モデルとNASHモデルの対比2013

    • Author(s)
      瓦谷 英人, 守屋 圭, 高谷 広章, 堂原 彰敏, 辻本 達寛, 吉治 仁志, 藤本 正男, 植村 正人, 福井 博
    • Organizer
      第17回日本肝臓学会大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Presentation] Distinct role of EGFR and Met on adult hepatic progenitor cell differentiation in mice2013

    • Author(s)
      Kitade M, Yoshiji H, Snorri Thorgeirsson, Fukui H
    • Organizer
      Annual Meeting of the Japanese Society for the Research of Hepatic Cells
    • Place of Presentation
      Osaka
    • Year and Date
      2013-09-26
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] 内因性エンドトキシン制御による肝線維化抑制2013

    • Author(s)
      堂原彰敏,吉治仁志,福井博
    • Organizer
      第99回日本消化器病学会総会
    • Place of Presentation
      鹿児島
    • Year and Date
      2013-03-26
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Presentation] インターフェロン,リバビリン,Angiotensin-II受容体阻害薬(ARB)の3剤併用による肝線維化抑制効果:抗血管新生作用との関連2013

    • Author(s)
      吉治仁志他
    • Organizer
      日本消化器病学会総会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] Direct renin inhibitor attenuates rat hepatocarcinogenesisi via anti-angiogenic activity2013

    • Author(s)
      Aihara Y, Yoshiji H, Noguchi R, Kaji K, Namisaki T, Moriya K, Kitade M, Fukui H
    • Organizer
      AACR Annual Meeting 2013
    • Place of Presentation
      Washington, DC.
    • Year and Date
      2013-04-10
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] 内因性エンドトキシン制御による肝線維化抑制:作用機序の検討2013

    • Author(s)
      堂原彰敏、堂原 彰敏, 吉治 仁志, 守屋 圭, 野口 隆一, 浪崎 正, 相原 洋祐, 瓦谷 英人, 福井 博
    • Organizer
      第49回日本肝臓学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Presentation] 肝障害をめぐる腸肝相関DSS腸炎モデルとNASHモデルの対比2013

    • Author(s)
      瓦谷英人,守屋圭,高谷広章,堂原彰敏,辻本達寛,吉治仁志,藤本正男,植村正人,福井博
    • Organizer
      第17回日本肝臓学会大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Presentation] Combined treatment of sorafenib and angiotensin-IIreceptor blocker attenuates preneoplastic lesion development of non-alcoholic steatohepatitis in rats2013

    • Author(s)
      Yoshiji H, Noguchi,R, Namisaki T. Moriya K, Kitade M, Aihara Y, Douhara A, Kawaratani H, Nishimura N, Fukui H
    • Organizer
      International Society for Hepatic Sinusoidal Research
    • Place of Presentation
      Osaka
    • Year and Date
      2013-09-24
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] Response-guided anti-angiogenic therapy for hepatocellular carcinoma recurrence with clinically available safety agent2013

    • Author(s)
      Yoshiji H, Noguchi R, Kaji K, Aihara Y, Namisaki T, Moriya K, Douhara A, Kitade M, Fukui H
    • Organizer
      AACR Annual Meeting 2013
    • Place of Presentation
      Washington, DC.
    • Year and Date
      2013-04-10
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] Inhibition of endotoxin cascade with antibiotics attenuates the liver fibrosis development in rat model of nonalcoholic steatohepatitis2013

    • Author(s)
      Douhara A, Moriya K, Yoshiji H, Noguchi R, Namisaki T, Kitade M, Aihara Y, Kawaratani H, Nishimura N, Fukui H
    • Organizer
      International Society for Hepatic Sinusoidal Research
    • Place of Presentation
      Osaka
    • Year and Date
      2013-09-24
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] Inhibition of endotoxin cascade with antibiotics attenuates the liver fibrosis development in rat model of nonalcoholic steatohepatitis2013

    • Author(s)
      Douhara A, Moriya K, Yoshiji H, Noguchi R, Namisaki T, Kitade M, Aihara Y, Kawaratani H, Nishimura N, Fukui H.
    • Organizer
      International Society for Hepatic Sinusoidal Research
    • Place of Presentation
      大阪
    • Year and Date
      2013-09-24
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Presentation] ウルソデオキシコール酸とアンジオテンシンII受容体阻害薬併用によるNASH肝線維化進展抑制の試み2013

    • Author(s)
      浪崎正,吉治仁志,福井博
    • Organizer
      第49回日本肝臓学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Presentation] Combination of angiotensin-converting enzyme inhibitor and selective aldosterone blocker, suppresses the liver fibrosis carcinogenesis of nonalcoholic steatohepatitis in the rat2013

    • Author(s)
      Noguchi R, Yoshiji H, Namisaki T, Moriya K, Kitade M, Aihara Y, Douhara A, Kawaratani H, Nishimura N, Fukui H
    • Organizer
      International Society for Hepatic Sinusoidal Research
    • Place of Presentation
      Osaka
    • Year and Date
      2013-09-24
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] NASH肝線維化進展における腸管透過性亢進の役割2013

    • Author(s)
      堂原彰敏,吉治仁志,守屋圭,野口隆一,浪崎正,相原洋祐,瓦谷英人,北出光輝,福井博
    • Organizer
      第17回日本肝臓学会大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Presentation] NASH肝発癌に対するソラフェニブとangiotensin-II受容体阻害薬(ARB)の併用効果2013

    • Author(s)
      吉治仁志他
    • Organizer
      日本肝臓学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] Effect of sorafenib on HCV-related hepatocellular carcinoma (HCC)2012

    • Author(s)
      Douhara A, Moriya K, Yoshiji H, Noguchi R, Namisaki T, Kaji K, Aihara Y, Yamao J, Mitoro A, Fukui H
    • Organizer
      JSH Single Topic Conference
    • Place of Presentation
      Tokyo
    • Year and Date
      2012-11-21
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] Crosstalk between glucose intolerance and liver fibrosis development in patients with chronic hepatitis C2012

    • Author(s)
      Aihara Y, Yoshiji H, Noguchi R, Namisaki T, Moriya K, Kaji K, Douhara A, Fukui H
    • Organizer
      JSH Single Topic Conference
    • Place of Presentation
      Tokyo
    • Year and Date
      2012-11-21
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] Expression of TLR4 and TNF-a in the rat dextran sulfate sodium(DSS) induced colitis model2012

    • Author(s)
      K awaratani H, Moriya K, Takaya H, Douhara A, Yoshiji H, Fujimoto M, Uemura M, Fukui H.
    • Organizer
      IEIIS2012
    • Place of Presentation
      東京
    • Year and Date
      2012-10-23
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Presentation] Therapeutic effect of cytokine modulator Y-40138 in the rat alcoholic liver disease model2012

    • Author(s)
      Kawaratani H, Tsujimoto T, Moriya K, Douhara A, Takaya H, Mitoro A, Yoshiji H, Uemura M, Fukui H.
    • Organizer
      IEIIS2012
    • Place of Presentation
      東京
    • Year and Date
      2012-10-24
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Presentation] Chemoprevention of HCV-associated HCC by BCAA and ACE-inhibitor2012

    • Author(s)
      Yoshiji H
    • Organizer
      JSH Single Topic Conference
    • Place of Presentation
      Tokyo
    • Year and Date
      2012-11-22
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] Douhara A, Aihara Y, Yamao J, Mitoro A, Fukui H. Efficacy of combination therapy with peg-interferon alpha and ribavirin in elderly chronic hepatitis C2012

    • Author(s)
      Moriya K, Yoshiji H, Noguchi R, Namisaki T, Kaji K
    • Organizer
      JSH Single Topic Conference
    • Place of Presentation
      Tokyo
    • Year and Date
      2012-11-21
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] Sorafenibとangiotensin-II受容体阻害薬 (ARB)併用による肝発癌抑制2012

    • Author(s)
      吉治仁志
    • Organizer
      日本肝臓学会
    • Place of Presentation
      神戸国際会議場
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] Inhibitory effect of selective aldosterone blocker on hepatocellular carcinoma development via angiogenesis suppression2011

    • Author(s)
      Kaji K, Yoshiji H, Ikenaka Y, Noguchi R, Fukui H
    • Organizer
      ILCA
    • Place of Presentation
      Hong-Kong
    • Year and Date
      2011-09-03
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] Combination of branched-chain amino acid and angiotensin-converting enzyme inhibitor suppresses the cumulative recurrence of hepatocellular carcinoma under the condition of insulin resistance2011

    • Author(s)
      Yoshiji H, Ikenaka Y, Noguchi R, Kaji K, Aihara Y, Fukui H
    • Organizer
      ASIA-PACIFIC PRIMARY LIVER CANCER EXPERT MEETING
    • Place of Presentation
      Osaka
    • Year and Date
      2011-07-03
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] Combination of branched-amino acids and angiotensin-converting enzyme inhibitor attenuates the insulin resintance-based hepatocarcinogenesis via angiogenesis suppression2011

    • Author(s)
      Aihara Y, Yoshiji H, Ikenaka Y, Noguchi R, Kaji K, Fukui H
    • Organizer
      ASIA-PACIFIC PRIMARY LIVER CANCER EXPERT MEETING
    • Place of Presentation
      Osaka
    • Year and Date
      2011-07-03
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] 肝線維化に対する血管新生因子VEGFおよびインスリンをターゲットとした分子標的治療2011

    • Author(s)
      吉治仁志
    • Organizer
      日本肝臓学会
    • Place of Presentation
      福岡国際センター
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] Combination of branched-amino acids and angiotensin-converting enzyme inhibitor attenuates the insulin resistance -based hepatocarcinogenesis via angiogenesis suppression2011

    • Author(s)
      Aihara Y, Yoshiji H, Ikenaka Y, Noguchi R, Kaji K, Fukui H
    • Organizer
      ILCA
    • Place of Presentation
      Hong-Kong
    • Year and Date
      2011-09-03
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] Clinically available selective aldosterone blocker attenuates hepatocarcinogenesis via angiogenesis inhibition in rats2011

    • Author(s)
      Noguchi R, Yoshiji H, Ikenaka Y, Aihara Y, Fukui H
    • Organizer
      ILCA
    • Place of Presentation
      Hong-Kong
    • Year and Date
      2011-09-03
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] Soluble VEGF receptor-2 may be a predictive marker of anti-angiogenic chemopreventive therapy with clinically available safe agents2011

    • Author(s)
      Yoshiji H, Ikenaka Y, Noguchi R, Kaji K, Aihara Y, Fukui H
    • Organizer
      ILCA
    • Place of Presentation
      Hong-Kong
    • Year and Date
      2011-09-03
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] Clinically available selective aldosterone blocker attenuates hepatocarcinogenesis via angiogenesis inhibition in rats2011

    • Author(s)
      Noguchi R, Yoshiji H, Ikenaka Y, Kaji K, Shirai Y, Fukui H
    • Organizer
      ASIA-PACIFIC PRIMARY LIVER CANCER EXPERT MEETING
    • Place of Presentation
      Osaka
    • Year and Date
      2011-07-03
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] Inhibitory effect of selective aldosterone blocker on hepatocellular carcinoma development via angiogenesis suppression2011

    • Author(s)
      Kaji K, Yoshiji H, Ikenaka Y, Noguchi R, Aihara Y, Fukui H
    • Organizer
      ASIA-PACIFIC PRIMARY LIVER CANCER EXPERT MEETING
    • Place of Presentation
      Osaka
    • Year and Date
      2011-07-03
    • Data Source
      KAKENHI-PROJECT-23590986
  • [Presentation] An alternatice VEGF-targeted therapy and possible prediction against hepatocellular carcinoma(HCC) using combination of clinically available agents.2010

    • Author(s)
      吉治仁志
    • Organizer
      Choshu International Liver Symposium 2010.
    • Year and Date
      2010-02-06
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] Clinically used selective aldosterone blocker attenuates hepatocarcinogenesis via angiogenesis inhibition in rats.2010

    • Author(s)
      野口隆一, 吉治仁志, 池中康英, 鍛治孝祐, 白井勇作, 福井博
    • Organizer
      AACR.
    • Year and Date
      2010-04-20
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] An alternative VEGF-targeted therapy and possible prediction against hepatocellular carcinoma(HCC) using combination of clinically available agents.2010

    • Author(s)
      吉治仁志, 池中康英, 野口隆一, 鍛治孝祐, 白井勇作, 福井博
    • Organizer
      AACR.
    • Year and Date
      2010-04-20
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] インスリン抵抗性を示す肝硬変患者における肝癌再発予防2010

    • Author(s)
      吉治仁志, 他
    • Organizer
      日本肝臓学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2010-10-13
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] 選択的アルドステロン阻害薬による抗血管新生に基づく肝発癌抑制効果2010

    • Author(s)
      野口隆一、吉治仁志、池中康英、鍛治孝祐、白井勇作、相原洋祐、福井博
    • Organizer
      日本癌学会学術総会
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] Renin-angiotensin system in hepatic fibrogenesis.2010

    • Author(s)
      吉治仁志, 池中康英, 野口隆一, 鍛治孝祐, 白井勇作, 相原洋祐, 福井博
    • Organizer
      JSH Single Topic Conference.
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] インスリン抵抗性条件下肝癌再発に対する安全な既存薬剤を用いたVEGFを分子標的とした新規治療法2010

    • Author(s)
      吉治仁志、野口隆一、北出光輝、鍛治孝祐、池中康英、白井勇作、相原洋祐、福井博
    • Organizer
      日本癌学会学術総会
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] インスリン抵抗性を示す肝硬変患者における肝癌再発予防:分枝鎖アミノ酸(BCAA)とACE阻害薬の併用は肝癌発生を抑制するか2010

    • Author(s)
      吉治仁志、鍛治孝祐、福井博
    • Organizer
      日本消化器病学会大会
    • Year and Date
      2010-10-15
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] アンジオテンシンIIとアルドステロンdual blockによるNASH肝線維化進展抑制の試み2010

    • Author(s)
      野口隆一、吉治仁志、福井博
    • Organizer
      日本消化器病学会大会
    • Year and Date
      2010-10-15
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] NASHにおける可溶性VEGF Receptor2サイトケラチン18、および細胞膜リン脂質成分変化の治療判定応用の可能性2010

    • Author(s)
      吉治仁志、鍛治孝祐、福井博
    • Organizer
      日本肝臓学会総会
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] NASH進展過程におけるアルドステロンの役割と選択的アルドステロン阻害薬による治療の試み2010

    • Author(s)
      野口隆一、吉治仁志、福井博
    • Organizer
      日本肝臓学会総会
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] 肝炎ウイルスによる肝癌に対する分子標的治療2010

    • Author(s)
      吉治仁志、野口隆一、福井博
    • Organizer
      日本感染症学会総会
    • Year and Date
      2010-04-05
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] Amelioration of the Non-alcoholic steatohepatitis by clinically available selective aldosterone blocker in rats.2010

    • Author(s)
      野口隆一, 吉治仁志, 鍛治孝祐, 相原洋祐, 福井博
    • Organizer
      JSH Single Topic Conference.
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] インスリン抵抗性条件下における分枝鎖アミノ酸(BCAA)とACE阻害薬併用による肝発癌予防2009

    • Author(s)
      吉治仁志、鍛治孝祐、福井博
    • Organizer
      日本消化器病学会総会
    • Year and Date
      2009-05-09
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] 血管新生阻害に基づくBCAAとACE阻害薬併用によるインシュリン抵抗性条件下肝発癌抑制効果2009

    • Author(s)
      吉治仁志、野口隆一、北出光輝、加治幸祐、池中康英、白井勇作、浪崎正、山崎正晴、福井博
    • Organizer
      日本癌学会学術総会
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] 選択的アルドステロンブロッカーによる肝線維化抑制効果の検討2009

    • Author(s)
      野口隆一、吉治仁志、池中康英、北出光輝、鍛治孝祐、浪崎正、吉井純一、簗瀬公嗣、福井博
    • Organizer
      日本消化器病学会総会
    • Year and Date
      2009-05-09
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] 肝線維化進展におけるアルドステロンの役割と作用機序2009

    • Author(s)
      野口隆一、吉治仁志、福井博
    • Organizer
      日本肝臓学会大会
    • Year and Date
      2009-10-15
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] 選択的アルドステロン阻害剤による血管新生阻害と肝癌発育抑制2009

    • Author(s)
      野口隆一、吉治仁志、北出光輝、鍛治孝祐、池中康英、白井勇作、浪崎正、山崎正晴、福井博
    • Organizer
      日本癌学会学術総会
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] Suppressive effect on the cumulative recurrence of hepatocellular carcinoma with combination treatment of clinically available vitamin K2 and angiotensin-converting enzyme inhibitor.2009

    • Author(s)
      野口隆一, 吉治仁志, 池中康英, 北出光輝, 鍛治孝祐, 浪崎正, 相原洋祐, 福井博
    • Organizer
      APASL
    • Year and Date
      2009-02-14
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] ACE阻害剤、ビタミンK杯用による肝癌の分子標的治療:VEGFの変動からみた肝癌再発抑制効果の予測2009

    • Author(s)
      吉治仁志, 他
    • Organizer
      日本肝臓学会総会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] NASH病態における血管新生とサイトケラチン18の意義2009

    • Author(s)
      吉治仁志、鍛治孝祐、福井博
    • Organizer
      日本肝臓学会西部会
    • Year and Date
      2009-12-05
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] ACE阻害剤、ビタミンK杯用による肝癌の分子標的治療:VEGFの変動からみた肝癌再発抑制効果の予測2009

    • Author(s)
      吉治仁志、野口隆一、福井博
    • Organizer
      日本肝臓学会大会
    • Year and Date
      2009-10-15
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] 非アルコール性脂肪性肝炎における自然免疫:クッパー細胞機能と新しい診断と治療への応用2009

    • Author(s)
      野口隆一、吉治仁志、池中康英、鍛治孝祐、浪崎正、吉井純一、簗瀬公嗣、福井博
    • Organizer
      日本肝臓学会総会
    • Year and Date
      2009-06-04
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] インスリン抵抗性条件下の肝癌発生における血管新生の関与:分枝鎖アミノ酸(BCAA)とACE阻害薬併用による予防の試み2009

    • Author(s)
      吉治仁志、池中康英、野口隆一、北出光輝、鍛治孝祐、白井勇作、浪崎正、吉井純一、簗瀬公嗣、山崎正晴、福井博
    • Organizer
      日本肝臓学会総会
    • Year and Date
      2009-06-04
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] 非アルコール性脂肪肝炎における造影超音波検査と肝病態との関連2009

    • Author(s)
      藤本正男, 植村正人, 山尾純一, 吉治仁志, 辻本達寛, 北澤利幸, 北出光輝, 瓦谷英人, 福井博
    • Organizer
      第45回日本肝臓学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2009-06-05
    • Data Source
      KAKENHI-PROJECT-19590784
  • [Presentation] VEGF-targeted therapy against insulin -resistance-based rat hepatocarcinogenesis with clinically available agent : branched-chain amino acid (BCAA) granules.2009

    • Author(s)
      吉治仁志, 野口隆一, 北出光輝, 鍛治孝祐, 池中康英, 浪崎正, 相原洋祐, 福井博
    • Organizer
      APASL
    • Year and Date
      2009-02-14
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] 非アルコール性脂肪性肝炎における自然免疫;クッパー細胞機能と新しい診断と治療への応用2009

    • Author(s)
      辻本達寛, 瓦谷英人, 北澤利幸, 吉治仁志, 藤本正男, 植村正人, 福井博
    • Organizer
      第45回日本肝臓学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2009-06-05
    • Data Source
      KAKENHI-PROJECT-19590784
  • [Presentation] 血管新生とインスリン抵抗性の肝線維化進展における役割:慢性C型肝炎患者における検討2009

    • Author(s)
      野口隆一、吉治仁志、池中康英、浪崎正、北出光輝、鍛治孝祐、白井勇作、福井博
    • Organizer
      日本肝臓学会西部会
    • Year and Date
      2009-12-05
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] ラットNASHモデルにおける造影超音波造影能とクッパー細胞機能2008

    • Author(s)
      辻本達寛, 瓦谷英人, 北澤利幸, 吉治仁志, 藤本正男, 平井都始子, 植村正人, 福井博
    • Organizer
      第44回日本肝臓学会総会
    • Place of Presentation
      松山
    • Year and Date
      2008-06-06
    • Data Source
      KAKENHI-PROJECT-19590784
  • [Presentation] 膵癌発育におけるGemcitabineとLosartan併用による相乗的抗腫瘍効果:血管新生の関与2008

    • Author(s)
      野口隆一、吉治仁志、池中康英、北出光輝、鍛治孝祐、浪崎正、吉井純一、簗瀬公嗣、山崎正晴、福井博
    • Organizer
      日本癌学会学術総会
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] インスリン抵抗性条件下での肝発癌におけるVEGFに対する分子標的治療の試み:BCAA製剤を用いた検討2008

    • Author(s)
      吉治仁志、鍛治孝祐、福井博
    • Organizer
      日本肝臓学会大会
    • Year and Date
      2008-10-01
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] インスリン抵抗性条件下におけるVEGFを標的としたBCAA製剤による肝発癌抑制効果2008

    • Author(s)
      吉治仁志、北出光輝、鍛治孝祐、池中康英、野口隆一、浪崎正、吉井純一、簗瀬公嗣、山崎正晴、福井博
    • Organizer
      日本癌学会学術総会
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] インスリン抵抗性条件下でのVEGFに対する分子標的治療の試み2008

    • Author(s)
      吉治仁志, ほか
    • Organizer
      日本肝臓学会総会
    • Place of Presentation
      東京
    • Year and Date
      2008-10-01
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] サイトカイン産生調節薬Y-40138のNASHモデルに対する効果:新しい免疫的治療法の可能性2008

    • Author(s)
      辻本達寛, 瓦谷英人, 北澤利幸, 山崎正晴, 吉治仁志, 藤本正男, 植村正人, 福井博
    • Organizer
      第50回日本消化器病学会大会
    • Place of Presentation
      東京
    • Year and Date
      2008-10-02
    • Data Source
      KAKENHI-PROJECT-19590784
  • [Presentation] Gemcitabin無効例に対するARB併用による膵癌発育抑制効果とその機序:血管新生因子VEGFの関与2008

    • Author(s)
      野口隆一、吉治仁志、鍛治孝祐、北出光輝、池中康英、山崎正晴、福井博
    • Organizer
      日本消化器病学会大会
    • Year and Date
      2008-10-03
    • Data Source
      KAKENHI-PROJECT-20590792
  • [Presentation] Kupffer cell dysfunction in the rat non-alcoholic steatohepatitis (NASH) model.2007

    • Author(s)
      Tsujimoto T, Kawaratani H, Kitazawa T, Yoshiji H, Fujimoto M, Hirai T, Uemura M, Fukui H
    • Organizer
      Asian Pacific Digestive Week
    • Place of Presentation
      Kobe
    • Year and Date
      2007-10-18
    • Data Source
      KAKENHI-PROJECT-19590784
  • [Presentation] Role of the TLR-4-based innate immune response in the rat non-alcoholic steatohepatitis (NASH).2007

    • Author(s)
      Kawaratani H, Tsujimoto T, Kitazawa T, Yoshiji H, Uemura M, Fukui H
    • Organizer
      Asian Pacific Digestive Week
    • Place of Presentation
      Kobe
    • Year and Date
      2007-10-18
    • Data Source
      KAKENHI-PROJECT-19590784
  • [Presentation] ラットNASHモデルにおける肝内TNF-α産生2007

    • Author(s)
      辻本達寛, 瓦谷英人, 北澤利幸, 吉治仁志, 藤本正男, 平井都始子, 植村正人, 福井博
    • Organizer
      第11回日本肝臓学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2007-10-19
    • Data Source
      KAKENHI-PROJECT-19590784
  • [Presentation] Mouse models of fibrosis2006

    • Author(s)
      Yoshiji, H
    • Organizer
      AASLD single topic conference "Hepatic fibrosis"
    • Place of Presentation
      USA, Virginia
    • Year and Date
      2006-05-10
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590668
  • [Presentation] インスリン抵抗性条件下におけるDPP4阻害薬とARB併用による新規肝線維化治療の試み.

    • Author(s)
      野口隆一、吉治仁志、福井博.
    • Organizer
      第50回日本肝臓学会総会
    • Place of Presentation
      東京
    • Year and Date
      2014-05-29 – 2014-05-30
    • Data Source
      KAKENHI-PROJECT-26461017
  • [Presentation] 内因性エンドトキシン抑制によるNASH肝線維化抑制効果

    • Author(s)
      堂原彰敏、吉治仁志、福井 博
    • Organizer
      第99回日本消化器病学会総会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Presentation] Therapeutic effect of cytokine modulator Y-40138 in the rat alcoholic liver disease model

    • Author(s)
      Kawaratani H, Tsujimoto T, Moriya K, Douhara A, Takaya H, Mitoro A, Yoshiji H, Uemura M, Fukui H
    • Organizer
      【IEIIS2012】Homeostatic Inflammation Symposium
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Presentation] Expression of TLR4 and TNF-α in the rat dextran sulfate sodium(DSS) induced colitis model

    • Author(s)
      Kawaratani H, Moriya K, Takaya H, Douhara A, Yoshiji H, Fujimoto M, Uemura M, Fukui H
    • Organizer
      【IEIIS2012】Homeostatic Inflammation Symposium
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-23590987
  • [Presentation] アンジオテンシンⅡ制御による肝線維化の抑制と肝再生の促進.

    • Author(s)
      北出光輝、吉治仁志、福井博
    • Organizer
      第50回日本肝臓学会総会
    • Place of Presentation
      東京
    • Year and Date
      2014-05-29 – 2014-05-30
    • Data Source
      KAKENHI-PROJECT-26461017
  • 1.  NAMISAKI Tadashi (20526850)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 40 results
  • 2.  鍛治 孝祐 (20623490)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 46 results
  • 3.  NOGUCHI Ryuuichi (30423908)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 83 results
  • 4.  KITADE MITSUTERU (40526795)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 37 results
  • 5.  KOJIMA Hideyuki (60326345)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 6.  FUKUI Hiroshi (80145838)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 37 results
  • 7.  FUJIMOTO Masao (60295805)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 15 results
  • 8.  MORIYA KEI (40526852)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 12 results
  • 9.  辻本 達寛 (00423921)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 15 results
  • 10.  高谷 広章 (40745460)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 11.  NISHIMURA NORIHISA
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 13 results
  • 12.  MATSUMOTO MASANORI (60316081)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  MASHITANI TSUYOSHI (20401929)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 14.  KURIYAMA Shigeki (50244710)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 15.  KUROKOHCHI Kazutaka (10294753)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  MASAKI Tsutomu (30335848)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  IMAZU Hiroo (60336857)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  TOYOHARA Masahisa (50336856)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  YAMAO Jun-ichi (10221649)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  福井 博 (80145383)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  美登路 昭 (10382285)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  赤羽 たけみ (70423910)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  仲川 洋介 (00714875)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  赤羽 学 (40326327)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  井上 隆 (00783044)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  芝本 彰彦 (20896724)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  佐藤 慎哉 (80790352)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  KITAZAWA Hiroyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 29.  KAWARATANI Hideto
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 30.  賀屋 大介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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