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KINOSHITA Ichiro  木下 一郎

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Researcher Number 40343008
Other IDs
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Affiliation (Current) 2019: 北海道大学, 医学研究院, 准教授
Affiliation (based on the past Project Information) *help 2017 – 2018: 北海道大学, 医学研究院, 准教授
2016: 北海道大学, 医学研究科, 准教授
2012 – 2015: 北海道大学, 医学(系)研究科(研究院), 准教授
2014: 北海道大学, 大学院医学研究科, 准教授
2012: 北海道大学, 大学院・医学研究科, 准教授 … More
2011: 北海道大学, 医学(系)研究科(研究院), 講師
2007 – 2010: 北海道大学, 大学院・医学研究科, 講師
2006: Hokkaido University, Graduate SChool of Medicine, Lecturer, 大学院医学研究科, 講師
2004 – 2005: 北海道大学, 大学院・医学研究科, 講師 Less
Review Section/Research Field
Principal Investigator
Respiratory organ internal medicine
Except Principal Investigator
Respiratory organ internal medicine / Tumor diagnosis / Basic Section 53030:Respiratory medicine-related
Keywords
Principal Investigator
肺癌 / AP-1 / c-jun / EZH2 / 転写因子 / cJun / 癌幹細胞 / 幹細胞 / HDAC / 分子標的薬 … More / ヒストン修飾 / 分子標的 / MCM4 / マイクロアレイ / 遺伝子 / 癌 / インテグリンα6 / 癌遺伝子 / mcm4 / cJun / エピジェネティクス / DZNep / SAHA / side population / ヒストン修飾酵素 / 非小細胞肺癌 / EGFR / 遺伝子治療 / 分子生物学 / トランスフォーメーション / lung cancer / gene therapy / molecular biology / transcription factor / transformation / JARID1 / 薬剤耐性 / 抗癌薬耐性 … More
Except Principal Investigator
肺癌 / 非小細胞肺癌 / 糖転移酵素 / α1,6-フコース転移酵素 / AKR1B10 / バイオマーカー / 糖鎖 / 糖転移酵素〓1-6fucosyltransferase / alfa 1-6フコース転移酵素 / alfa1,6-フコース転移酵素 / 併用治療効果 / Notch / Notch / Bim / Bcl2 family / Lung cancer / 国際情報交換 / EGFR-TKI / 薬剤耐性 / FRETバイオセンサー / バイオイメージング / フェルスター共鳴エネルギー移動 / 分子マーカー / EGF受容体遺伝子変異 / 喫煙 / 扁平上皮癌 / タバコ発癌 / lung cancer / biomarker / EGFR mutation Less
  • Research Projects

    (11 results)
  • Research Products

    (50 results)
  • Co-Researchers

    (28 People)
  •  肺癌組織系の違いによるNumbの肺癌増殖に対する機能についてOngoing

    • Principal Investigator
      榊原 純
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Hokkaido University
  •  非小細胞肺癌における抗癌薬耐性化の克服を目指したヒストン修飾酵素阻害療法の開発Principal InvestigatorOngoing

    • Principal Investigator
      木下 一郎
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Hokkaido University
  •  Combined inhibition of stem cell markers and histone modification enzymes in non-small cell lung cancerPrincipal Investigator

    • Principal Investigator
      Kinoshita Ichiro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Hokkaido University
  •  Study on EGFR-TKI resistance using FRET biosensor

    • Principal Investigator
      Akita Hirotoshi
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Hokkaido University
  •  Combined antitumor effec ot g-secretase inbitiro and ABT-737

    • Principal Investigator
      SAKAKIBARA Jun
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Hokkaido University
  •  Targeted therapy for cancer stem-like cells of non-small cell lung cancers with inhibition of the cJun transcription factorPrincipal Investigator

    • Principal Investigator
      KINOSHITA Ichiro
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Hokkaido University
  •  Alteration of fucosylation and biomarker development in lung cancer

    • Principal Investigator
      AKITA Hirotoshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor diagnosis
    • Research Institution
      Hokkaido University
  •  Identification of novel molecular targets for lung cancer based on different sensitivity to AP-1 blockadePrincipal Investigator

    • Principal Investigator
      KINOSHITA Ichiro
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Hokkaido University
  •  肺癌および随伴肺疾患における糖転移酵素の発現異常に関する研究

    • Principal Investigator
      AKITA Hirotoshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Hokkaido University
  •  Research on Molecular Therapeutic Targets and Biomarkers for the Diagnosis and Stratification in Lung Cancer

    • Principal Investigator
      AKITA Hirotoshi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Hokkaido University
  •  Growth inhibition of non-small cell lung cancer cells by AP-1 blockade using a cJun dominant negative mutant, TAM67Principal Investigator

    • Principal Investigator
      KINOSHITA Ichiro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      HOKKAIDO UNIVERSITY

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2004 Other

All Journal Article Presentation

  • [Journal Article] Updated survival outcomes of NEJ005/TCOG0902: a randomised phase II study of concurrent versus sequential alternating gefitinib and chemotherapy in previously untreated non-small cell lung cancer with sensitive EGFR mutations2018

    • Author(s)
      Oizumi S, Sugawara S, Minato K, Harada T, Inoue A, Fujita Y, Maemondo M, Watanabe S, Ito K, Gemma A, Demura Y, Fukumoto S, Isobe H, Kinoshita I, Morita S, Kobayashi K, Hagiwara K, Aiba K, Nukiwa T.
    • Journal Title

      ESMO Open

      Volume: 3(2)

    • DOI
      10.1136/esmoopen-2017-000313
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09562, KAKENHI-PROJECT-17K09639, KAKENHI-PROJECT-15K09164, KAKENHI-PROJECT-15K09168, KAKENHI-PROJECT-15K09237
  • [Journal Article] Combined antitumor effect of γ-secretase inhibitor and ABT-737 in Notch-expressing non-small cell lung cancer2017

    • Author(s)
      Sakakibara-Konishi J, Ikezawa Y, Oizumi S, Kikuchi J, Kikuchi E, Mizugaki H, Kinoshita I, Dosaka-Akita H, Nishimura M
    • Journal Title

      Int J Clin Oncol

      Volume: 22 Pages: 481-487

    • DOI
      10.1007/s10147-016-1060-3
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461175
  • [Journal Article] A randomized phase II trial of erlotinib vs. S-1 as a third- or fourth-line therapy for patients with wild-type EGFR non-small cell lung cancer (HOT1002)2017

    • Author(s)
      Ikezawa Y, Asahina H, Oizumi S, Watanabe M, Takamura K, Kawai Y, Yamada N, Harada T, Kinoshita I, Fujita Y, Miyauchi E, Ogi T, Amano T, Furuta M, Sakakibara-Konishi J, Nishihara H, Dosaka-Akita H, Isobe H, Nishimura M; Hokkaido Lung Cancer Clinical Study Group
    • Journal Title

      Cancer Chemother Pharmacol

      Volume: 80 Pages: 955-963

    • DOI
      10.1007/s00280-017-3432-4
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09639, KAKENHI-PROJECT-15K09164
  • [Journal Article] A phase II study of bevacizumab with carboplatin-pemetrexed in non-squamous non-small cell lung carcinoma patients with malignant pleural effusions: North East Japan Study Group Trial NEJ013A2016

    • Author(s)
      Usui K, Sugawara S, Nishitsuji M, Fujita Y, Inoue A, Mouri A, Watanabe H, Sakai H, Kinoshita I, Ohhara Y, Maemondo M, Kagamu H, Hagiwara K, Kobayashi K
    • Journal Title

      Lung Cancer

      Volume: 99 Pages: 131-136

    • DOI
      10.1016/j.lungcan.2016.07.003
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293196, KAKENHI-PROJECT-26461175
  • [Journal Article] Combined inhibition of EZH2 and HDACs as a potential epigenetic therapy for non-small cell lung cancer cells2016

    • Author(s)
      Takashina T, Kinoshita I, Kikuchi J, Shimizu Y, Sakakibara-Konishi J, Oizumi S, Nishimura M, and Dosaka-Akita H
    • Journal Title

      Cancer Sci

      Volume: (in press)

    • Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461175
  • [Journal Article] Novel signaling collaboration between TGF-β and adaptor protein Crk facilitates EMT in human lung cancer2016

    • Author(s)
      Elmansuri AZ, Tanino MA, Mahabir R, Wang L, Kimura T, Nishihara H, Kinoshita I, Dosaka-Akita H, Tsuda M and Tanaka S
    • Journal Title

      Oncotarget

      Volume: (in press) Pages: 27094-107

    • DOI
      10.18632/oncotarget.8314
    • Peer Reviewed / Open Access / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461175, KAKENHI-PROJECT-15K15106, KAKENHI-PROJECT-25460471, KAKENHI-PROJECT-26670414, KAKENHI-PROJECT-15K08359, KAKENHI-PROJECT-16K08703
  • [Journal Article] The coordinated actions of TIM-3 on cancer and myeloid cells in the regulation of tumorigenicity and clinical prognosis in clear cell renal cell carcinomas2015

    • Author(s)
      Komohara Y, Morita T, Annan DA, Horlad H, Ohnishi K, Yamada S, Nakayama T, Kitada S, Suzu S, Kinoshita I, Dosaka-Akita H, Akashi K, Takeya M, Jinushi M
    • Journal Title

      Cancer Immunol Res

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461175
  • [Journal Article] Randomized phase II study of concurrent versus sequential alternating gefitinib and chemotherapy in previously untreated non-small cell lung cancer with sensitive EGFR mutations: NEJ005/TCOG09022015

    • Author(s)
      Sugawara S, Oizumi S, Minato K, Harada T, Inoue A, Fujita Y, Maemondo M, Yoshizawa H, Ito K, Gemma A, Nishitsuji M, Harada M, Isobe H, Kinoshita I, Morita S, Kobayashi K, Hagiwara K, Kurihara M, Nukiwa T; North East Japan Study Group and Tokyo Cooperative Oncology Group
    • Journal Title

      Ann Oncol

      Volume: 26(5) Pages: 888-94

    • DOI
      10.1093/annonc/mdv063
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461172, KAKENHI-PROJECT-26461175, KAKENHI-PROJECT-15K09164
  • [Journal Article] Factors associated with a poor response to gefitinib in the NEJ002 study: Smoking and the L858R mutation2015

    • Author(s)
      Fukuhara T, Yoshizawa H et al.
    • Journal Title

      Lung Cancer

      Volume: 88 Pages: 181-186

    • DOI
      10.1016/j.lungcan.2015.02.004
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24591156, KAKENHI-PROJECT-25461172, KAKENHI-PROJECT-26461175, KAKENHI-PROJECT-15K09164, KAKENHI-PROJECT-15K09237, KAKENHI-PROJECT-15K15320
  • [Journal Article] Expression of Fucosyltransferase 8 Is Associated with an Unfavorable Clinical Outcome in Non-Small Cell Lung Cancers2015

    • Author(s)
      Honma R, Kinoshita I, Miyoshi E, Tomaru U, Matsuno Y, Shimizu Y, Takeuchi S, Kobayashi Y, Kaga K, Taniguchi N, Dosaka-Akita H
    • Journal Title

      Oncology

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461175
  • [Journal Article] Immune regulation of therapy-resistant niches: emerging targets for improving anticancer drug responses.2014

    • Author(s)
      Yamashina T, Baghdadi M, Yoneda A, Kinoshita I, Suzu S, Dosaka-Akita H, Jinushi M.
    • Journal Title

      Cancer Metastasis Rev.

      Volume: 74 Pages: 2698-2709

    • DOI
      10.1158/0008-5472.can-13-2169
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23501283, KAKENHI-PROJECT-23591132, KAKENHI-PUBLICLY-25112701, KAKENHI-PUBLICLY-25130701, KAKENHI-PROJECT-26290050, KAKENHI-PROJECT-26461175, KAKENHI-PROJECT-26670183
  • [Journal Article] CD133 expression : a potential prognostic marker for non-small cell lung cancers2014

    • Author(s)
      Mizugaki H, Sakakibara-Konishi J, Kinoshita I, Dosaka-Akita H, (他7名)
    • Journal Title

      Int J Clin Oncol

      Volume: 19 Pages: 254-259

    • DOI
      10.1007/s10147-013-0541-x
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591132
  • [Journal Article] Updated overall survival results from a randomized phase III trial comparing gefitinib with carboplatin–paclitaxel for chemo-Naïve non-small cell lung cancer with sensitive EGFR gene mutations (NEJ002).2013

    • Author(s)
      Inoue A, Kobayashi K, Maemondo M, et al
    • Journal Title

      Ann Oncol.

      Volume: 24 Pages: 54-59

    • DOI
      10.1093/annonc/mds214
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790746, KAKENHI-PROJECT-23591132, KAKENHI-PROJECT-24240042, KAKENHI-PROJECT-24591156, KAKENHI-PROJECT-24591184, KAKENHI-PROJECT-24659396
  • [Journal Article] TIM-4 glycoprotein - mediated degradation of dying tumor cells by autophagy leads to reduced antigen presentation and increased immune tolerance2013

    • Author(s)
      Baghdadi M, Yoneda A, Yamashina T, Nagao H, Komohara Y, Nagai S, Akiba H, Foretz M, Yoshiyama H, Kinoshita I, Dosaka-Akita H, Takeya M, Viollet B, Yagita H, Jinushi M
    • Journal Title

      Immunity

      Volume: 39 Pages: 1070-1081

    • DOI
      10.1016/j.immuni.2013.09.014
    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23130501, KAKENHI-PROJECT-23501283, KAKENHI-PROJECT-23590534, KAKENHI-PROJECT-23591132, KAKENHI-PROJECT-24790479, KAKENHI-PUBLICLY-25112701, KAKENHI-PUBLICLY-25130701, KAKENHI-PROJECT-25293089, KAKENHI-PROJECT-25461503
  • [Journal Article] Epigenetic therapy with 3-deazaneplanocin A, an inhibitor of the histone methyltransferase EZH2,inhibits growth of non-small cell lung cancer cells2012

    • Author(s)
      Kikuchi J, Takashina T, Kinoshita I, Kikuchi E, Shimizu Y , (他5名)
    • Journal Title

      Lung Cancer

      Volume: 78 Pages: 138-143

    • DOI
      10.1016/j.lungcan.2012.08.003
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591132
  • [Journal Article] Expression of Bim, Noxa, and Puma in non-small cell lung cancer.2012

    • Author(s)
      Sakakibara-Konishi J, Oizumi S, Kikuchi J, Kikuchi E, Mizugaki H, Kinoshita I, Dosaka-Akita H, Nishimura M
    • Journal Title

      BMC Cancer.

      Volume: 12 Pages: 286-286

    • DOI
      10.1186/1471-2407-12-286
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591146
  • [Journal Article] ATM-Mediated DNA Damage Signals Mediate Immune Escape through Integrin-alphavbeta3-Dependent Mechanisms2012

    • Author(s)
      Jinushi M
    • Journal Title

      Cancer Research

      Volume: 72 Pages: 56-65

    • DOI
      10.1158/0008-5472.can-11-2028
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390113, KAKENHI-PROJECT-21689031, KAKENHI-PROJECT-22240089, KAKENHI-PUBLICLY-23130501, KAKENHI-PROJECT-23590534, KAKENHI-PROJECT-23591132
  • [Journal Article] Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between thereceptor TIM-3 and the alarmin HMGB12012

    • Author(s)
      Chiba, M. Baghdadi, H. Akiba, H. Yoshiyama, I. Kinoshita, H. Dosaka-Akita, Y. Fujioka, Y. Ohba, J. V. Gorman, J. D. Colgan, M. Hirashima, T. Uede, A. Takaoka, H. Yagita and M. Jinushi.
    • Journal Title

      Nature Immunology

      Volume: 13 Pages: 832-42

    • DOI
      10.1038/ni.2376
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J04616, KAKENHI-PROJECT-21390113, KAKENHI-PROJECT-22240089, KAKENHI-PROJECT-22590360, KAKENHI-PROJECT-22591098, KAKENHI-PROJECT-23390090, KAKENHI-PROJECT-23501283, KAKENHI-PROJECT-23590534, KAKENHI-PROJECT-23591132, KAKENHI-PROJECT-23659196, KAKENHI-PUBLICLY-23114501
  • [Journal Article] Minichromosome maintenance (MCM) protein 4 as a marker for proliferation and its clinical and clinicopathological significance in non-small cell lung cancer2011

    • Author(s)
      Kikuchi J, Kinoshita I, Shimizu Y, Kikuchi E, Takeda K, Aburatani H, Oizumi S, Konishi J, Kaga K, Matsuno Y, Birrer MJ, Nishimura M and Dosaka-Akita H
    • Journal Title

      Lung Cancer

      Volume: 72 Pages: 229-237

    • DOI
      10.1016/j.lungcan.2010.08.020
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591132
  • [Journal Article] Expression of LGR5, an intestinal stem cell marker, during each stage of colorectal tumorigenesis2011

    • Author(s)
      Takeda K, Kinoshita I, Shimizu Y, Matsuno Y, Shichinohe T and Dosaka-Akita H
    • Journal Title

      Anticancer Res

      Volume: 31 Pages: 263-270

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591132
  • [Journal Article] Minichromosome maintenance (MCM) protein 4 as a marker for proliferation and its clinical and clinicopathological significance in non-small cell lung cancer.2011

    • Author(s)
      Kikuchi J, Kinoshita I, Birrer MJ, Dosaka-Akita H
    • Journal Title

      Lung Cancer. 72

      Pages: 229-37

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590909
  • [Journal Article] Tumor-associated macrophages regulate tumorigenicity and anti-cancer drug responses of cancer stem/initiating cells.2011

    • Author(s)
      Jinushi M, Chiba S, Yoshiyama H, Masutomi K, Kinoshita I, Dosaka-Akita H, Yagita H, Takaoka A, Tahara H
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 108 Pages: 112425-12430

    • DOI
      10.1073/pnas.1106645108
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249069, KAKENHI-PROJECT-21689031, KAKENHI-PROJECT-22240089, KAKENHI-PUBLICLY-23130501, KAKENHI-PROJECT-23590534, KAKENHI-PROJECT-23591132
  • [Journal Article] Minichromosome maintenance (MCM) protein 4 as a marker for proliferation and its clinical and clinicopathological significance in non-small cell lung cancer.2010

    • Author(s)
      Kikuchi J, Kinoshita I, et.al.
    • Journal Title

      Lung Cancer

      Volume: 172(9月(Epub))

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590909
  • [Journal Article] Distinctive expression of the polycomb group proteins Bmi1 polycomb ring finger oncogene and enhancer of zeste homolog 2 in nonsmall cell lung cancers and their clinical and clinicopathologic significance.2010

    • Author(s)
      Kikuchi J, Kinoshita I, Dosaka-Akita H
    • Journal Title

      Cancer 116

      Pages: 3015-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590909
  • [Journal Article] Distinctive expression of the polycomb group proteins Bmil polycomb ring finger oncogene and enhancer of zeste homolog 2 in nonsmall cell lung cancers and their clinical and clinicopathologic significance.2010

    • Author(s)
      Kikuchi J, Kinoshita I, et.al.
    • Journal Title

      Cancer

      Volume: 116 Pages: 3015-3024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590909
  • [Journal Article] Simultaneous blockade of AP-1 and phosphatidylinositol 3-kinase pathway in non-small cell lung cancer cells.2008

    • Author(s)
      Kikuchi J, Kinoshita I, Birrer MJ, Dosaka-Akita H
    • Journal Title

      Br J Cancer 99(12)

      Pages: 2013-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590909
  • [Journal Article] 肺癌の遺伝子異常2004

    • Author(s)
      木下一郎, 他
    • Journal Title

      呼吸と循環 52・10

      Pages: 1059-1064

    • Data Source
      KAKENHI-PROJECT-16590729
  • [Presentation] JARIDファミリー阻害薬の非小細胞肺癌細胞株に対する効果2017

    • Author(s)
      有賀伸、木下一郎、菊地順子、清水康、秋田弘俊
    • Organizer
      第58回日本肺癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K09639
  • [Presentation] 非小細胞肺癌におけるヒストン修飾酵素阻害療法に関する研究2017

    • Author(s)
      木下一郎、秋田弘俊
    • Organizer
      第二回北大・部局横断シンポジウム
    • Place of Presentation
      北海道大学(北海道・札幌市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-26461175
  • [Presentation] EZH2阻害薬とヒストン脱アセチル化酵素(HDAC)阻害薬の併用療法の非小細胞肺癌(NSCLC)細胞に対する抗腫瘍効果2014

    • Author(s)
      木下一郎,高階太一、菊地順子、榊原純、大泉聡史、西村正治、秋田弘俊
    • Organizer
      第18回日本がん分子標的治療学会学術集会
    • Place of Presentation
      TKPガーデンシティ仙台(宮城県・仙台市)
    • Year and Date
      2014-06-26
    • Data Source
      KAKENHI-PROJECT-26461175
  • [Presentation] Prognostic significance of 〓1,6 fucosyltransferase (〓1,6 FT) in non-small cell lung cancers (NSCLCs).2013

    • Author(s)
      Honma R, Dosaka-Akita H, Kinoshita I
    • Organizer
      2013 Annual Meeting of American Society of Clinical Oncology (ASCO).
    • Place of Presentation
      McCormick Place (シカゴ、米国).
    • Year and Date
      2013-06-01
    • Data Source
      KAKENHI-PROJECT-22501029
  • [Presentation] Role of polycomb group protein EZH2 in lung cancer2012

    • Author(s)
      Kinoshita I
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      教育文化会館, 札幌市
    • Year and Date
      2012-09-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591132
  • [Presentation] Pharmacologic disruption of polycomb group protein EZH2 via 3-Deazaneplanocin A inhibits growth of non-small cell lung cancer cells2012

    • Author(s)
      Kinoshita I
    • Organizer
      5th Asia Pacific Lung Cancer Conference
    • Place of Presentation
      Hilton Fukuoka Sea Hawk, Fukuoka
    • Year and Date
      2012-11-26
    • Data Source
      KAKENHI-PROJECT-23591132
  • [Presentation] Decreased expression of GMDand GDP-fucose transporter is associated with squamous histology in NSCLCs.2011

    • Author(s)
      Honma R, Dosaka-Akita H, Kinoshita I
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場.
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-22501029
  • [Presentation] Decreased expression of GMD in non-small cell lung cancers (NSCLCs).2011

    • Author(s)
      Honma R, Dosaka-Akita H, Kinoshita I
    • Organizer
      102nd Annual Meeting of AmericanAssociation of Cancer Research (AACR).
    • Place of Presentation
      Orange CountyConvention Center(オーランド、米国)
    • Year and Date
      2011-04-05
    • Data Source
      KAKENHI-PROJECT-22501029
  • [Presentation] Growth inhibition of non-small cell lung cancer cells by the histone methyltransferase ezh2 inhibitor 3-deazaneplanocin2011

    • Author(s)
      Kinoshita I
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場, 名古屋市
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-23591132
  • [Presentation] Growth inhibition of non-small cell lung cancer cells by the histone methyltransferase ezh2 inhibitor 3-deazaneplanocin2011

    • Author(s)
      Kinoshita I
    • Organizer
      9th International Symposium for Future Drug Discovery and Medical Care
    • Place of Presentation
      Hokkaido University, Sapporo
    • Year and Date
      2011-09-30
    • Data Source
      KAKENHI-PROJECT-23591132
  • [Presentation] Growth inhibition of non-small cell lung cancer cells by the histone methyltransferase ezh2 inhibitor 3-deazaneplanocin2011

    • Author(s)
      Kinoshita I, Kikuchi J, Shimizu Y, Sakakibara-Konishi J, Oizumi S, Nishimura M, Dosaka-Akita H
    • Organizer
      9th International Symposium for Future Drug Discovery and Medical Care
    • Place of Presentation
      北海道大学(札幌市)
    • Data Source
      KAKENHI-PROJECT-23591132
  • [Presentation] GDP-mannose-4,6-dehydratase (GMD) and GDP-fucose transporter in non-small cell lung cancers (NSCLCs) : their decreased expression insquamous cell carcinomas by immunohistochemistry.2011

    • Author(s)
      Honma R, Dosaka-Akita H, Kinoshita I
    • Organizer
      14th World Conference on Lung Cancer of International Association for the Studyof Lung Cancer.
    • Place of Presentation
      Amsterdam RAI(アムステルダム、オラ ンダ)
    • Year and Date
      2011-07-05
    • Data Source
      KAKENHI-PROJECT-22501029
  • [Presentation] Growth inhibition of non-small cell lung cancer cells by the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin2011

    • Author(s)
      木下一郎,菊地順子,菊地英毅, 清水康, 榊原純, 大泉聡史, 西村正治, 秋田弘俊
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知)
    • Data Source
      KAKENHI-PROJECT-23591132
  • [Presentation] Distinctive expression of polycomb group proteins Bmil and EZH2 in nonsmall cell lung cancers and their clinical and clinicopathological significance.2010

    • Author(s)
      Kikuchi J, Kinoshita I, et.al.
    • Organizer
      101th Annual Meeting of the American Association for Cancer Research
    • Place of Presentation
      Washington Convention Center (Washington, DC, USA)
    • Year and Date
      2010-04-20
    • Data Source
      KAKENHI-PROJECT-20590909
  • [Presentation] 非小細胞肺癌におけるポリコーム蛋白質Bmi1とEZH2の発現の違いと臨床病理学的意義2010

    • Author(s)
      木下一郎, 他
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Year and Date
      2010-09-23
    • Data Source
      KAKENHI-PROJECT-20590909
  • [Presentation] The role of minichromosome maintenance (MCM) protein 4 in proliferation and its clinicopathological significance in non-small cell lung cancers (NSCLCs).2009

    • Author(s)
      Kinoshita I.
    • Organizer
      13th World Conference of Lung Cancer
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2009-08-02
    • Data Source
      KAKENHI-PROJECT-20590909
  • [Presentation] The role of minichromosome maintenance(MCM)protein 4 in proliferation and its clinicopathological significance in non-small cell lung cancers(NSCLCs).2009

    • Author(s)
      Kinoshita I, et.al.
    • Organizer
      13th World Conference of Lung Cancer
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2009-08-03
    • Data Source
      KAKENHI-PROJECT-20590909
  • [Presentation] EZH2阻害薬とヒストン脱アセチル化酵素阻害薬の併用療法の非小細胞肺癌細胞に対する抗腫瘍効果の検討

    • Author(s)
      高階太一、木下一郎、菊地順子、池澤靖元、榊原純、大泉聡史、西村正治、秋田弘俊
    • Organizer
      第54回日本肺癌学会総会
    • Place of Presentation
      ホテルニューオータニ(東京)
    • Data Source
      KAKENHI-PROJECT-23591132
  • [Presentation] Effects of combined epigenetic therapy with EZH2 and HDAC inhibitors on NSCLC cells

    • Author(s)
      Takashina T, Kinoshita I, Kikuchi J, Kikuchi E, Shimizu Y, Sakakibara-Konishi J, Oizumi S, Nishimura M and Dosaka-Akita H
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Data Source
      KAKENHI-PROJECT-23591132
  • [Presentation] Role of polycomb group protein EZH2 in lung cancer

    • Author(s)
      Kinoshita I
    • Organizer
      第71会日本癌学会学術総会
    • Place of Presentation
      教育文化会館(札幌市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591132
  • [Presentation] Effects of combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin and the histone deacetylase inhibitor SAHA on non-small cell lung cancer cells

    • Author(s)
      Takashina T, Kinoshita I, Kikuchi J, Shimizu Y, Konishi JS, Oizumi S, Nishimura M and Dosaka-Akita H
    • Organizer
      the 105th Annual Meeting of the American Association for Cancer Research
    • Place of Presentation
      San Diego Conventon Center (San Diego)
    • Data Source
      KAKENHI-PROJECT-23591132
  • [Presentation] Pharmacologic disruption of polycomb group protein EZH2 via 3-Deazaneplanocin A inhibits growth of non-small cell lung cancer cells

    • Author(s)
      Kinoshita I
    • Organizer
      5th Asia Pacific Lung Cancer Conference
    • Place of Presentation
      Hilton Fukuoka Sea Hawk (Fukuoka)
    • Data Source
      KAKENHI-PROJECT-23591132
  • [Presentation] ヒストンメチル化酵素EZH2阻害剤3-deazaneplanocin Aによる非小細胞肺癌細胞株に対する増殖抑制効果の検討

    • Author(s)
      高階太一、木下一郎、菊地順子、菊地英毅、清水康、榊原純、大泉聡史、西村正治、秋田弘俊
    • Organizer
      第53回日本肺癌学会総会
    • Place of Presentation
      岡山コンベンションセンター(岡山市)
    • Data Source
      KAKENHI-PROJECT-23591132
  • 1.  AKITA Hirotoshi (70222528)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 16 results
  • 2.  SAKAKIBARA Jun (50374278)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  SHIMIZU Yasushi (10374513)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 4.  JINUSHI Masahisa (40318085)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 5.  Ohba Yusuke (30333503)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  YAMAZAKI Koichi (20312358)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  三善 英知 (20322183)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  GENMA Akihiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 9.  OIZUMI Satoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 10.  INOUE Kenich
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  WATANABE Satoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  TANINO Mishie
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  YOSHIZAWA Hirohisa
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 14.  KOMOHARA Yoshihiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  各務 博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  小林 国彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  前門戸 任
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 18.  田原 秀晃
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  八木田 秀雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 20.  吉山 裕規
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 21.  津田 真寿美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  田中 伸哉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  木村 太一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  西條 康夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 25.  井上 彰
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  秋葉 久弥
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 27.  永井 重徳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  竹屋 元裕
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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