YOSHIKAWA Yoshiro 吉川義朗

Researcher Number	40343420
Affiliation (based on the past Project Information) *help	2011 – 2013: 奈良県立医科大学, 医学部, 講師 2006 – 2009: Nara medical university, School of medicine, assistant professor, 医学部, 講師 2004 – 2005: 奈良県立医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Thoracic surgery Except Principal Investigator Thoracic surgery
Keywords	Principal Investigator カルパイン阻害剤 / NCX inhibitor / gene transfer / cross-circulation method / calpain inhibitor / failing heart / mechanoenergetics / コンダクタンスカテーテル / 心力学的・エネルギー学的評価 / NCX阻害剤 … More / 遺伝子導入 / 血液交差灌流 / 不全心 / 心力学的・エネルギー学的 / 心筋虚血再灌流 / カルパイン阻害薬 / 虚血再灌流障害 / 心保存 / 生理学 / 発現抑制 / 遺伝子 / 移植・再生医療 / 循環器・高血圧 / 心臓大血管外科学 … More Except Principal Investigator RNAi / Phospholamban / SERCA2a / failing heart / Gene transfer / 不全心 / 遺伝子導入 Less

カルパイン阻害剤による心保存後の虚血再灌流障害予防効果に関する研究Principal Investigator
- Principal Investigator
  
  吉川義朗
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Nara Medical University
Development of the novel gene transfer technique combining RNAi and ultrasonic intervention for the severe cardiac dysfunctionPrincipal Investigator
- Principal Investigator
  
  YOSHIKAWA Yoshiro, TSUJI Tsuyoshi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Nara Medical University
Development of new therapy that combines gene transfer into serious failing heart with RNAi
- Principal Investigator
  
  TSUJI Tsuyoshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Nara Medical University
Cross-circulation Method in mice: To investigate the efficacy of gene transfer to the failing mice heart.Principal Investigator
- Principal Investigator
  
  YOSHIKAWA Yoshiro
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Nara Medical University

All 2013 2012 2010 2009 2008 2007 2005 2004 Other

All Journal Article Presentation

[Journal Article] A new calpain inhibitor protects left ventricular dysfunction induced by mild ischemia-reperfusion in in situ rat hearts.2013
- Author(s)
  Takeshita D, Obata K, Takak M, 他6名
- Journal Title
  
  JPhysiol Sci
  
  Volume: 63 Issue: 2 Pages: 113-123
- DOI
  10.1007/s12576-012-0243-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500487, KAKENHI-PROJECT-22500489, KAKENHI-PROJECT-23592046, KAKENHI-PROJECT-25460283
[Journal Article] Aortic root replacement for Valsalva sinus aneurysm with lupus erythematosus.2012
- Author(s)
  Hirose T, Kameda Y, Yoshikawa Y, Abe T, Hayata Y, Taniguchi S.
- Journal Title
  
  Asian Cardiovasc Thorac Ann.
  
  Volume: 20(2) Issue: 2 Pages: 193-5
- DOI
  10.1177/0218492311422028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592046
[Journal Article] Isolated dissecting aneurysm of the brachiocephalic artery associated with contained rupture.2012
- Author(s)
  Hirose T, Tabayashi N, Yoshikawa Y, Abe T, Naito H, Hayata Y, Yamashita K, Taniguchi S.
- Journal Title
  
  Gen Thorac Cardiovasc Surg.
  
  Volume: 60 Issue: 4 Pages: 225-227
- DOI
  10.1007/s11748-011-0809-x
- NAID
  10031121086
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592046
[Journal Article] Cardioprotective effects of a novel calpain inhibitor SNJ-1945 for reperfusion injury after cardioplegic cardiac arrest.2010
- Author(s)
  Yoshikawa Y, Zhang GX, Obata K, Ohga Y, Matsuyoshi H, Taniguchi S, Takaki M
- Journal Title
  
  Am J Physiol Heart Circ Physiol 298(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591643
[Journal Article] Cardioprotective effects of a novel calpain inhibitor SNJ-1945 for reperfusion injury after cardioplegic cardiac arrest2010
- Author(s)
  Yoshikawa Y, Takaki M, ほか5名
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 298(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591643
[Journal Article] Rescue of Ca^<2+> overload-induced left ventricular dysfunction by targeted ablation of phospholan2009
- Author(s)
  Tsuji T, Yoshikawa Y, ほか7名
- Journal Title
  
  Am J Physiol Heart Circ Physiol 296(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591643
[Journal Article] Rescue of Ca2+ overload-induced left ventricular dysfunction by targeted ablation of phospholamban.2009
- Author(s)
  Tsuji T, Del Monte F, Yoshikawa Y, Abe T, Shimizu J, Nakajima-Takenaka C, Taniguchi S, Najjar RJ, Takaki M
- Journal Title
  
  Am J Physiol Heart Circ Physiol 296(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591643
[Journal Article] Calpain inhibitor-1 protects the rat heart from ischemia-reperfusion injury : analysis by mechanical work and energetics.2005
- Author(s)
  Yoshiro Yoshikawa, Hiroji Hagihara, Yoshimi Ohga, Chikako Nakajima-Takenaka, Ken-ya Murata, Shigeki Taniguchi, Miyako Takaki
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 288(4)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591404
[Journal Article] Calpain inhibitor-1 protects the rat heart from ischemic-reperfusion injury : analysis by mechanical work and energetics2005
- Author(s)
  Yoshikawa Yoshiro他6名の共著
- Journal Title
  
  American Journal of Physiology Heart and Circulatory Physiology 288
  
  Pages: 1690-1698
- Data Source
  KAKENHI-PROJECT-16591404
[Journal Article] Na+/Ca2+ exchange inhibition protects the rat heart from ischemia-reperfusion injury by blocking energy-wasting processes.2005
- Author(s)
  Hiroji Hagihara, Yoshiro Yoshikawa, Yoshimi Ohga, Chikako Takenaka, Ken-ya Murata, Shigeki Taniguchi, Miyako Takaki
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 288(4)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591404
[Journal Article] Calpain inhibitor-1 protects the rat heart from ischemia-reperfusion injury : analysis by mechanical work and energetics2005
- Author(s)
  Yoshiro Yoshikawa他6名の共著
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 288(4)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591404
[Journal Article] Rescue of Ca2+ overload-induced left ventricle dysfunction by targeted ablation of phospholamban.2004
- Author(s)
  Tsuyoshi Tsuji, Federica del Monte, Yoshiro Yoshikawa, Takehisa Abe, Shigeki Taniguchi, Miyako Takaki, Roger J. Hajjar
- Journal Title
  
  J Mol Cell Cardiol. 37(5)
  
  Pages: 1084-1084
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591404
[Journal Article] A cardioprotective agent of a novel calpain inhibitor, SNJ-1945 exerts β1-actions on left ventricular mechanical work and energetics
- Author(s)
  Yoshikawa Y, Zhang GX, Obata K, Matsuyoshi H, Asada K, Taniguchi S, Takaki M
- Journal Title
  
  Am J Physiol Heart Circ Physiol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591643
[Journal Article] Calpain inhibitor-1 protects the rat heart from ischemic-reperfusion injury : analysis by mechanical work and energetics
- Author(s)
  Yoshikawa Yoshiro他6名の共著
- Journal Title
  
  American Journal of Physiology Heart and Circulatory Physiology (in press)
- Data Source
  KAKENHI-PROJECT-16591404
[Presentation] 肺出血を来した超低出生体重児に対するPDA閉鎖術の工夫2012
- Author(s)
  吉川義朗、早田義宏、多林伸起、阿部毅寿、廣瀬友亮、山下慶悟、平賀俊、谷口繁樹
- Organizer
  第42回日本心臓血管外科学会学術総会
- Place of Presentation
  秋田
- Data Source
  KAKENHI-PROJECT-23592046
[Presentation] 新しいカルパイン阻害剤SNJ-1945添加心筋保護液の虚血再灌流障害防止効果:ラット血液交叉灌流摘出心臓標本を用いて2010
- Author(s)
  吉川義朗, 張国興, 小畑孝二, 大賀好美, 松吉ひろ子, 谷口繁樹, 高木都
- Organizer
  第31回日本循環制御医学会総会
- Place of Presentation
  大阪府豊中市
- Data Source
  KAKENHI-PROJECT-19591643
[Presentation] 大動脈遮断解除後の再灌流障害予防における水溶性カルパイン阻害剤の有用性2009
- Author(s)
  吉川義朗, 高木都, ほか5名
- Organizer
  第39回日本心臓血管外科学会総会
- Place of Presentation
  富山国際会議場
- Data Source
  KAKENHI-PROJECT-19591643
[Presentation] 大動脈遮断解除後の再灌流障害予防における水溶性カルパイン阻害剤の有用性2009
- Author(s)
  吉川義朗, 多林伸起, 張国興, 阿部毅寿, 清水寿一郎, 谷口繁樹, 高木都
- Organizer
  第39回日本心臓血管外科学会学術総会
- Place of Presentation
  富山県富山市
- Data Source
  KAKENHI-PROJECT-19591643
[Presentation] 大動脈遮断解除後の再灌流障害予防における水溶性カルパイン阻害剤の効果:ラット血液交叉灌流摘出心臓標本を用いて2008
- Author(s)
  吉川義朗, 藤根潔枝, 清水壽一郎, 大賀好美, 谷口繁樹, 高木都
- Organizer
  第13回病態と治療におけるプロテアーゼとインヒビター学会学術集会
- Place of Presentation
  大阪府豊中市
- Year and Date
  2008-08-22
- Data Source
  KAKENHI-PROJECT-19591643
[Presentation] 大動脈遮断解除後の再灌流障害予防における水溶性カルパイン阻害剤の効果 : ラット血液交叉灌流摘出心臓標本を用いて2008
- Author(s)
  吉川義朗, ほか6名
- Organizer
  第13回病態と治療におけるプロテアーゼとインヒビター学会
- Place of Presentation
  大阪
- Year and Date
  2008-08-22
- Data Source
  KAKENHI-PROJECT-19591643
[Presentation] 選択的β1ブロッカーランジオールの特性:血液交叉灌流摘出ラット心臓を用いるメカノエナジェティクスからのアプローチ2007
- Author(s)
  吉川義朗、辻毅嗣、高木都
- Organizer
  題60回日本胸部外科学会定期学術集会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-19591643
[Presentation] 選択的β1プロッカーランジオロールの特性;血液交叉灌流ラット心臓を用いるメカノエナジェティクスからのアプローチ2007
- Author(s)
  吉川義朗, 多林伸起, 辻毅嗣, 藤根潔枝, 清水寿一郎, 阿部毅寿, 谷口繁樹, 高木都
- Organizer
  第60回日本胸部外科学会定期学術集会
- Place of Presentation
  宮城県仙台市
- Data Source
  KAKENHI-PROJECT-19591643

1. TSUJI Tsuyoshi (50295804)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
2. TAKAKI Miyako (00033358)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. TAMURA Yamato (20382301)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. NAKAJIMA Chikako (50336848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 桑田俊之 (00398439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 小畑孝二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YOSHIKAWA Yoshiro 吉川 義朗

Research Projects

Research Products

Co-Researchers

カルパイン阻害剤による心保存後の虚血再灌流障害予防効果に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the novel gene transfer technique combining RNAi and ultrasonic intervention for the severe cardiac dysfunctionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new therapy that combines gene transfer into serious failing heart with RNAi

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cross-circulation Method in mice: To investigate the efficacy of gene transfer to the failing mice heart.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A new calpain inhibitor protects left ventricular dysfunction induced by mild ischemia-reperfusion in in situ rat hearts.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aortic root replacement for Valsalva sinus aneurysm with lupus erythematosus.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Isolated dissecting aneurysm of the brachiocephalic artery associated with contained rupture.2012

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Cardioprotective effects of a novel calpain inhibitor SNJ-1945 for reperfusion injury after cardioplegic cardiac arrest.2010

Author(s)

Journal Title

Data Source

[Journal Article] Cardioprotective effects of a novel calpain inhibitor SNJ-1945 for reperfusion injury after cardioplegic cardiac arrest2010

Author(s)

Journal Title

Data Source

[Journal Article] Rescue of Ca^<2+> overload-induced left ventricular dysfunction by targeted ablation of phospholan2009

Author(s)

Journal Title

Data Source

[Journal Article] Rescue of Ca2+ overload-induced left ventricular dysfunction by targeted ablation of phospholamban.2009

Author(s)

Journal Title

Data Source

[Journal Article] Calpain inhibitor-1 protects the rat heart from ischemia-reperfusion injury : analysis by mechanical work and energetics.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Calpain inhibitor-1 protects the rat heart from ischemic-reperfusion injury : analysis by mechanical work and energetics2005

Author(s)

Journal Title

Data Source

[Journal Article] Na+/Ca2+ exchange inhibition protects the rat heart from ischemia-reperfusion injury by blocking energy-wasting processes.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Calpain inhibitor-1 protects the rat heart from ischemia-reperfusion injury : analysis by mechanical work and energetics2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Rescue of Ca2+ overload-induced left ventricle dysfunction by targeted ablation of phospholamban.2004

YOSHIKAWA Yoshiro 吉川義朗