SAWADA Naoki 澤田直樹

… Alternative Names

澤田直樹サワダナオキ

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Researcher Number	40343751
Affiliation (based on the past Project Information) *help	2012: 東京医科歯科大学, 歯と骨のＧＣＯＥ拠点, ＧＣＯＥ拠点形成特任教員 2010 – 2012: 東京医科歯科大学, 歯と骨のGCOE拠点, GCOE拠点形成特任教員 2003: 生産開発科学研, 研究員 2002: 財団法人生産開発科学研究所, その他部局等, 研究員
Review Section/Research Field	Principal Investigator Biological Sciences / Circulatory organs internal medicine / Circulatory organs internal medicine
Keywords	Principal Investigator 内皮由来神経栄養活性 / 神経再生 / 神経幹細胞ニッチ / 転写コアクチベータ / 血管新生 / 分子血管病態学 / ノックアウトマウス / トランスジェニックマウス / Rhoキナーゼ / Rho … More / 低分子量G蛋白 / Gキナーゼ / cGMP / ナトリウム利尿ペプチド Less

血管内皮による神経再生作用の賦活化におけるＲａｃ１　ＧＴＰａｓｅの意義の検討Principal Investigator
- Principal Investigator
  
  澤田直樹
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
The regulation of endothelial migration and angiogenesis by transcriptiona l coact I vator PGC-1aIphaPrincipal Investigator
- Principal Investigator
  
  SAWADA Naoki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokyo Medical and Dental University
GキナーゼによるRho/Rhoキナーゼ系抑制の血管統御・病態における意義の解析Principal Investigator
- Principal Investigator
  
  澤田直樹
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Research Institute for Production Development

All 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Glucose-independent persistence of PAl-1 gene expression and H3K4 tri-methylation in type 1 diabetic mouse endothelium; lmplication in metabolic memory2013
- Author(s)
  Takizawa F, Mizutani S, Ogawa Y Sawada N
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 433(1) Pages: 66-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590825
[Journal Article] Glucose-independent persistence of PAI-1 gene expression and H3K4 tri-methylation in type 1 diabetic mouse endothelium: implication in metabolic memory.2013
- Author(s)
  Takizawa F, Mizutani S, Ogawa Y, Sawada N.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 433(1) Issue: 1 Pages: 66-72
- DOI
  10.1016/j.bbrc.2013.02.064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590825, KAKENHI-PROJECT-23390240, KAKENHI-PUBLICLY-23122505
[Journal Article] Rho/Rho-Associated Coiled-Coil Forming Kinase Pathway as Therapeutic Targets for Statins in Atherosclerosis2013
- Author(s)
  Sawada N, Liao JK
- Journal Title
  
  Antioxid Redox Signal
  
  Volume: (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590825
[Journal Article] Role of transient receptor potential vanilloid 2 in LPS-induced cytokine production in macrophages2010
- Author(s)
  Yamashiro K, Sasano T, Tbjo K, Namekata l, Kurokawa J, Sawada N, Suganami T, Kamei Y Tanaka H,Tajima N, Utsunomiya K, Ogawa Y Furukawa T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 398(2) Pages: 284-289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590825
[Journal Article] Endothelial PGC-1α mediates vascular dysfunction in diabetes
- Author(s)
  Sawada N, Jiang A, Takizawa F, Safdar A, Manika A, Tesmenitsky Y, Kang K-T, Bischoff J, Kalwa H, Sartoretto J, Kamei Y, Benjamin LE, Watada H, Ogawa Y, Higashikuni Y, Kessinger CW, Jaffer FA, Michel T, Sata M, Croce K, Tanaka R, Arany Z
- Journal Title
  
  Cell Metab
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590825
[Presentation] Endothelial PGC-1alpha mediates vascular dysfunction in diabetes2013
- Author(s)
  Naoki Sawada, Aihua Jiang, Fumihiko Takizawa, Kevin Croce, Andre Manika, Yevgenia Tesmenitsky, Kyu Tae Kang, Joyce Bischoff, Hermann Kalwa, Thomas Michel, Yasutomi Kamei, Laura E. Benjamin, Masataka Sata, Shuki Mizutani, Yoshihiro Ogawa, Zolt Arany
- Organizer
  Gordon Research Conference, Vascular Cell Biology
- Place of Presentation
  Ventura, California, USA
- Data Source
  KAKENHI-PROJECT-22590825
[Presentation] Endothelial PGC-1alpha mediates vascular dysfunction in diabetes2013
- Author(s)
  Naoki Sawada, Aihua Jiang, Fumihiko Takizawa, Kevin Croce, Andre Manika, Yevgenia Tesmenitsky, Kyu Tae Kang, Joyce Bischoff, Hermann Kalwa, Thomas Michel,Yasutomi Kamei, Laura E. Benjamin, Masataka Sata, Yoshihiro Ogawa, Zolt Arany
- Organizer
  The American Society for Clinical lnvestigation/Association of American Physicians Joint Meeting
- Place of Presentation
  Chicago, lllinois, USA
- Data Source
  KAKENHI-PROJECT-22590825
[Presentation] Endothelial PGC-1alpha mediates vascular dysfunction in diabetes2013
- Author(s)
  Fumihiko Takizawa, Naoki Sawada, Aihua Jiang, Kevin Croce, Andre Manika, Yevgenia Tesmenitsky, Kyu Tae Kang, Joyce Bischoff, Hermann Kalwa, Thomas Michel, Laura E. Benjamin, Masataka Sata, Zolt Arany
- Organizer
  第77回日本循環器学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2013-03-16
- Data Source
  KAKENHI-PROJECT-22590825
[Presentation] Endothelial PGC-1alpha mediates vascular dysfunction in diabetes.2013
- Author(s)
  澤田直樹（代表者)
- Organizer
  The American Society for Clinical Investigation/Association of American Physicians Joint Meeting
- Place of Presentation
  Chicago, Illinois, USA
- Data Source
  KAKENHI-PROJECT-22590825
[Presentation] Endothelial PGC-1alpha mediates vascular dysfunction in diabetes.2013
- Author(s)
  澤田直樹（代表者)
- Organizer
  The American Society for Clinical Investigation/Association of American Physicians Joint Meeting
- Place of Presentation
  Chicago, Illinois, USA
- Year and Date
  2013-04-26
- Data Source
  KAKENHI-PUBLICLY-23122505
[Presentation] Endothelial PGC-1alpha mediates vascular dysfunction in diabetes2013
- Author(s)
  滝沢文彦、澤田直樹（代表者)
- Organizer
  第77回日本循環器学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2013-03-15
- Data Source
  KAKENHI-PUBLICLY-23122505
[Presentation] Endothelial PGC-1alpha mediates vascular dysfunction in diabetes.2013
- Author(s)
  澤田直樹（代表者)
- Organizer
  Gordon Research Conference, Vascular Cell Biology
- Place of Presentation
  Ventura, California, USA
- Data Source
  KAKENHI-PROJECT-22590825
[Presentation] Endothelial PGC-1alpha mediates vascular dysfunction in diabetes.2013
- Author(s)
  澤田直樹（代表者)
- Organizer
  Gordon Research Conference, Vascular Cell Biology
- Place of Presentation
  Ventura, California, USA
- Year and Date
  2013-01-27
- Data Source
  KAKENHI-PUBLICLY-23122505
[Presentation] Rac1 GTPase is a critical mediator of endothelium-derived neurotrophic activity.2012
- Author(s)
  Naoki Sawada, Yoshihiro Ogawa, James K. Liao.
- Organizer
  Neuro-Vascular Wiring Symposium 2012
- Place of Presentation
  奈良市
- Year and Date
  2012-11-12
- Data Source
  KAKENHI-PUBLICLY-23122505
[Presentation] Endothelial PGC-1alpha mediates vascular dysfunction in diabetes.2012
- Author(s)
  澤田直樹（代表者)
- Organizer
  ATVB Early Career Investigator Award competition, American Heart Association Scientific Sessions 2012
- Place of Presentation
  Los Angeles, California, USA
- Data Source
  KAKENHI-PROJECT-22590825
[Presentation] Rac1 GTPase is a critical mediator of endothelium-derived neurotrophic activity.2012
- Author(s)
  Naoki Sawada, Yoshihiro Ogawa, James K. Liao.
- Organizer
  Neuro-Vascular Wiring Symposium 2012
- Place of Presentation
  奈良市
- Data Source
  KAKENHI-PROJECT-22590825
[Presentation] Endothelial PGC-1alpha mediates vascular dysfunction in diabetes.2012
- Author(s)
  澤田直樹（代表者)
- Organizer
  ATVB Early Career Investigator Award competition, American Heart Association Scientific Sessions 2012
- Place of Presentation
  Los Angeles, California, USA
- Year and Date
  2012-11-03
- Data Source
  KAKENHI-PUBLICLY-23122505
[Presentation] Endothelial PGC-1alpha mediates vascular dysfunction in diabetes2012
- Author(s)
  Naoki Sawada, Aihua Jiang, Fumihiko Takizawa, Kevin Croce, Andre Manika, Yevgenia Tesmenitsky, Kyu Tae Kang, Joyce Bischoff, Hermann Kalwa, Thomas Michel, Yasutomi Kamei, Laura E. Benjamin, Masataka Sata, Shuki Mizutani, Yoshihiro Ogawa, Zolt Arany
- Organizer
  ATVB Early Career Investigator Award competition, American Heart Association Scientific Sessions 2012
- Place of Presentation
  Los Angeles, California, USA
- Data Source
  KAKENHI-PROJECT-22590825
[Presentation] Racl GTPase is a critical mediator of endothelium-derived neurotrophic activity2012
- Author(s)
  Naoki Sawada, Ybshihiro Ogawa, James K. Liao
- Organizer
  Neuro-Vascular Wiring Sym posium 2012
- Place of Presentation
  Nara, Japan
- Data Source
  KAKENHI-PROJECT-22590825
[Presentation] Endothelial PGC-1alpha is highly responsive to metabolic stress and serves as a key determinant of angiogenic response. Symposium' Young Scientist lnitiative Program2011
- Author(s)
  Naoki Sawada, Aihua Jiang, Fumihiko Takizawa, Kevin Croce, Andre Manika, Yevgenia Tesmenitsky, Kyu Tae Kang, Joyce Bischoff, Hermann Kalwa, Thomas Michel, Yasutomi Kamei, Laura E. Benjamin, Masataka Sata, Shuki Mizutani, Yoshihiro Ogawa, Zolt Arany
- Organizer
  The 19th Scientific session. Japanese Vascular Biology and Medical Organization
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-22590825

1. SATA Masataka (80345214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. ZOLT Arany

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results

SAWADA Naoki 澤田 直樹

澤田 直樹 サワダ ナオキ

Research Projects

Research Products

Co-Researchers

血管内皮による神経再生作用の賦活化におけるＲａｃ１ ＧＴＰａｓｅの意義の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The regulation of endothelial migration and angiogenesis by transcriptiona l coact I vator PGC-1aIphaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

GキナーゼによるRho/Rhoキナーゼ系抑制の血管統御・病態における意義の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Glucose-independent persistence of PAl-1 gene expression and H3K4 tri-methylation in type 1 diabetic mouse endothelium; lmplication in metabolic memory2013

Author(s)

Journal Title

Data Source

[Journal Article] Glucose-independent persistence of PAI-1 gene expression and H3K4 tri-methylation in type 1 diabetic mouse endothelium: implication in metabolic memory.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rho/Rho-Associated Coiled-Coil Forming Kinase Pathway as Therapeutic Targets for Statins in Atherosclerosis2013

Author(s)

Journal Title

Data Source

[Journal Article] Role of transient receptor potential vanilloid 2 in LPS-induced cytokine production in macrophages2010

Author(s)

Journal Title

Data Source

[Journal Article] Endothelial PGC-1α mediates vascular dysfunction in diabetes

Author(s)

Journal Title

Data Source

[Presentation] Endothelial PGC-1alpha mediates vascular dysfunction in diabetes2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Endothelial PGC-1alpha mediates vascular dysfunction in diabetes2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Endothelial PGC-1alpha mediates vascular dysfunction in diabetes2013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Endothelial PGC-1alpha mediates vascular dysfunction in diabetes.2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Endothelial PGC-1alpha mediates vascular dysfunction in diabetes.2013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Endothelial PGC-1alpha mediates vascular dysfunction in diabetes2013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Endothelial PGC-1alpha mediates vascular dysfunction in diabetes.2013

Author(s)

Organizer

SAWADA Naoki 澤田直樹

澤田直樹サワダナオキ

血管内皮による神経再生作用の賦活化におけるＲａｃ１　ＧＴＰａｓｅの意義の検討Principal Investigator