Tanabe Kazuhito 田邉一仁

… Alternative Names

田邊一仁タナベカズヒト

TANABE Kazuhito 田邉一仁

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Researcher Number	40346086
Other IDs
Affiliation (Current)	2025: 青山学院大学, 理工学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 青山学院大学, 理工学部, 教授 2015 – 2016: 青山学院大学, 理工学部, 教授 2014: 京都大学, 工学(系)研究科(研究院), 准教授 2012: 京都大学, 大学院・工学研究科, 准教授 2011 – 2012: 京都大学, 工学(系)研究科(研究院), 准教授 … More 2011: 京都大学, 工学研究科, 准教授 2009: 京都大学, 大学院・工学研究科, 准教授 2008 – 2009: Kyoto University, 工学研究科, 准教授 2007: Kyoto University, 工学研究科, 助教 2002 – 2006: Kyoto University, Energy and Hydrocarbon Chemistry, Instructor, 工学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 37010:Bio-related chemistry / Biological Sciences / Chemistry related to living body / Chemical biology / Bio-related chemistry / Physical pharmacy / Biological Sciences / Nanomaterials/Nanobioscience Except Principal Investigator Basic Section 37010:Bio-related chemistry / Radiation science / Physical chemistry
Keywords	Principal Investigator X線照射 / 低酸素細胞 / 人工核酸 / 放射線 / ジスルフィド結合 / ドラッグキャリア / ルテニウム錯体 / 低酸素環境 / 分子イメージング / 生物有機化学 … More / DNA / プロドラッグ / ニトロベンジル基 / 画像化 / 遺伝子制御 / 機能性薬剤 / 腫瘍低酸素 / セラノスティクス / 還元酵素 / 放射線照射 / ＤＮＡ会合体 / Ｘ線照射 / りん光 / 細胞核 / 放射線治療 / 酸素濃度 / 腫瘍イメージング / りん光発光 / 分子プローブ / 酸素濃度計測 / がん治療 / 両親媒性分子 / PEG / インドールキノン / クリック反応 / 会合体形成 / 両親媒性DNA / ドラッグデリバリー / 細胞内酸素濃度 / レシオ測定 / 虚血性疾患 / がん / DNA切断 / 光酸化反応 / ナフトキノン / 鎖切断 / 脱プロトン化 / 光反応 / メチル化シトシン / アンチセンス / 抗がん剤 / ケージド化合物 / ケージドペプチド / ケージドDNA / 放射線分解型置換基 / 光電流応答 / 金電極 / DNA三重鎖 / 機能性人工DNA / 光電流 / DNA固定化電極 / pH効果 / 三重鎖 / 電荷移動制御 / 機能性人口DNA / 光活性化 / 遺伝子配列識別 / 励起エネルギー移動 / ヘアピン型DNA / 光分子放出反応 / 光増感還元反応 / 光機能性核酸 / 遺伝子検出 … More Except Principal Investigator 1分子計測 / 核酸 / 反応速度 / 過渡構造 / ダイナミクス / 三重項ー三重項エネルギー移動 / ブリンキング / 蛍光 / １分子計測 / 光化学 / RNA / Structure-Activity Relationship / Radiosensitizing Effect / Cytotoxicity / Intercalation / DNA Strand Breaks / Hypoxic Tumor Cells / Nitroazole / Enediyne / エンジンプロドラッグ / 構造-活性相関 / 放射線増感効果 / 細胞毒性 / インターカレーション / DNA鎖切断 / 低酸素腫瘍細胞 / ニトロアゾール / エンジインプロドラッグ / アプタマー / 電子移動 / 核酸塩基損傷 / 時間分解分光測定 / 生物物理化学・DNA内電子移動 Less

蛍光ブリンキング制御による細胞内粘度・拡散速度の超解像計測
- Principal Investigator
  
  川井清彦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Tokyo Institute of Technology
Integrated understanding and manipulation of hypoxic cellular functions by artificial nucleic acids with hypoxia-accumulating propertiesPrincipal Investigator
- Principal Investigator
  
  田邉一仁
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Aoyama Gakuin University
Construction of RNA dynamics science and RNA-targeted drug assay systems
- Principal Investigator
  
  KAWAI KIYOHIKO
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Tokyo Institute of Technology
  Osaka University
Drug Design for Hypoxic TheranosticsPrincipal Investigator
- Principal Investigator
  
  Tanabe Kazuhito
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Aoyama Gakuin University
Evaluation of oxygen effect on radiolysis of tumor tissue on the basis of quantitative analysis of oxygen concentrationPrincipal Investigator
- Principal Investigator
  
  Tanabe Kazuhito
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Aoyama Gakuin University
  Kyoto University
Design of smart drugs that are activated upon X-irradiationPrincipal Investigator
- Principal Investigator
  
  Tanabe Kazuhito
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical biology
- Research Institution
  Aoyama Gakuin University
  Kyoto University
病的細胞の選択的可視化を指向した低酸素応答性蛍光プローブの開発Principal Investigator
- Principal Investigator
  
  田邊一仁
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Design of X-ray responsive drug carriers composed of oligodeoxynucleotidesPrincipal Investigator
- Principal Investigator
  
  TANABE Kazuhito
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Highly Efficient Excess Electron Transfer in Precisely Designed DNA Architectures
- Principal Investigator
  
  ITO Takeo
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical chemistry
- Research Institution
  Kyoto University
Detection of 5-methylcytosine in DNA by functionalized oligodeoxynucleotidesPrincipal Investigator
- Principal Investigator
  
  TANABE Kazuhito
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kyoto University
がんの放射線-化学併用療法を指向した放射線活性化型プロドラッグの開発Principal Investigator
- Principal Investigator
  
  田邊一仁
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
遺伝子配列識別能をもつ光活性化型ドラッグの開発Principal Investigator
- Principal Investigator
  
  田邉一仁
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
導電性のオン・オフ機能をもつDNAナノデバイスの開発Principal Investigator
- Principal Investigator
  
  田邉一仁
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  Kyoto University
二重鎮形成により機能性分子を放出する情報発信型核酸の開発Principal Investigator
- Principal Investigator
  
  田邉一仁
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kyoto University
Radiosensitizing Effect of Antitumor Enediyne Prodrugs Possessing DNA-Cleaving Activity under Hypoxic Conditions
- Principal Investigator
  
  NISHIMOTO Sei-ichi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  KYOTO UNIVERSITY

[Book] Drug Delivery System2015
- Author(s)
  田邉一仁（分担）
- Total Pages
  84
- Publisher
  じほうビジネスサービス
- Data Source
  KAKENHI-PROJECT-26560446
[Book] Drug Delivery System2015
- Author(s)
  田邉一仁（分担）
- Total Pages
  84
- Publisher
  じほうビジネスサービス
- Data Source
  KAKENHI-PROJECT-26288078
[Book] 実験医学２０１２年増刊号（疾患克服を目指した最新ケミカルバイオロジー）第2章―52012
- Author(s)
  田邉一仁
- Total Pages
  8
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-23113508
[Book] 化学フロンティアゲノム化学-医学、分子生物学への応用と展開 (齋藤烈, 杉山弘, 中谷和彦編)2007
- Author(s)
  田邉一仁
- Total Pages
  9
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-18015030
[Book] 化学フロンティアゲノム化学-医学、分子生物学への応心用と展開 (斎藤烈・杉山弘・中谷和彦編)2007
- Author(s)
  田邉一仁
- Total Pages
  9
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-17710099
[Book] 蛋白質核酸酵素 2007年10月号増刊ケミカルバイオロジー2007
- Author(s)
  田邊一仁・伊藤健雄・西本清一
- Total Pages
  6
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-18015030
[Journal Article] Hoechst‐Modification on Oligodeoxynucleotides for Efficient Transport to the Cell Nucleus and Gene Regulation2023
- Author(s)
  Makanai Hiroki、Nishihara Tatsuya、Nishikawa Makiya、Tanabe Kazuhito
- Journal Title
  
  ChemBioChem
  
  Volume: 25 Issue: 3
- DOI
  10.1002/cbic.202300645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K12691, KAKENHI-PROJECT-23K26779
[Journal Article] Encoding Thiol Metabolite Information into a DNA Sequence by Disulfide Exchange Reaction on Oligodeoxynucleotides for Parallel Analysis of the Metabolite and mRNA2023
- Author(s)
  Motohashi Yuto、Moritani Shuhei、Nishihara Tatsuya、Tanabe Kazuhito
- Journal Title
  
  ChemistrySelect
  
  Volume: 8 Issue: 29
- DOI
  10.1002/slct.202302662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K04966, KAKENHI-PROJECT-23K26779
[Journal Article] DNA Encoding Strategy for the Identification and Quantification of Poorly Reactive Target Metabolite Using Phenylboronic Acid-tethered Oligodeoxynucleotides2023
- Author(s)
  Motohashi Yuto、Nishihara Tatsuya、Tanabe Kazuhito
- Journal Title
  
  Chemistry Letters
  
  Volume: 52 Issue: 9 Pages: 732-735
- DOI
  10.1246/cl.230263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K04966, KAKENHI-PROJECT-23K26779
[Journal Article] Alkyne-tethered oligodeoxynucleotides that allow simultaneous detection of multiple DNA/RNA targets using Raman spectroscopy2023
- Author(s)
  Watanabe Hikaru、Maehara Daigo、Nishihara Tatsuya、Tanabe Kazuhito
- Journal Title
  
  RSC Advances
  
  Volume: 13 Issue: 30 Pages: 20756-20760
- DOI
  10.1039/d3ra03861k
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K26779
[Journal Article] Hypoxic X-irradiation as a trigger for reduction of metal ion and azide-alkyne cycloaddition on oligodeoxynucleotides2022
- Author(s)
  Akisawa Kento、Makanai Hiroki、Nishihara Tatsuya、Tanabe Kazuhito
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 92 Pages: 153658-153658
- DOI
  10.1016/j.tetlet.2022.153658
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02863
[Journal Article] Raman Signal Enhancement by DABCYL-Substitution on DNA Aptamer for Identification of Cellular ATP2022
- Author(s)
  Watanabe Hikaru、Maehara Daigo、Nishihara Tatsuya、Tanabe Kazuhito
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 33 Issue: 12 Pages: 2314-2319
- DOI
  10.1021/acs.bioconjchem.2c00541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02863
[Journal Article] Preparation of a multifunctional photoactivated prodrug on a streptavidin scaffold bearing a DNA aptamer.2022
- Author(s)
  Motohashi, Y.; Nishihara, T.; Tanabe, K.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 71 Pages: 128819-128819
- DOI
  10.1016/j.bmcl.2022.128819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02863
[Journal Article] Synthesis of Red‐Light‐Responsive Pheophorbide‐a Tryptamine Conjugated Photosensitizers for Photodynamic Therapy2022
- Author(s)
  Pandurang Taur Prakash、Kumar Bintu、Verma Narshimha、Dastidar Debabrata Ghosh、Yamada Risa、Nishihara Tatsuya、Tanabe Kazuhito、Kumar Dalip
- Journal Title
  
  ChemMedChem
  
  Volume: 18 Issue: 1
- DOI
  10.1002/cmdc.202200405
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02863
[Journal Article] Phosphonated mesoporous silica nanoparticles bearing ruthenium complexes used as molecular probes for tracking oxygen levels in cells and tissues2021
- Author(s)
  Umehara Yui、Kimura Yu、Kleitz Freddy、Nishihara Tatsuya、Kondo Teruyuki、Tanabe Kazuhito
- Journal Title
  
  RSC Advances
  
  Volume: 11 Issue: 10 Pages: 5865-5873
- DOI
  10.1039/d0ra08771h
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02863
[Journal Article] Changes of C≡C Triple Bond Vibration that Disclosed Non-Canonical Cytosine Protonation in i-Motif-Forming Oligodeoxynucleotides2021
- Author(s)
  Itaya, R.; Idei, W.; Nakamura, T.; Nishihara, T.; Kurihara, R.; Okamoto, A.; Tanabe, K.
- Journal Title
  
  ACS Omega
  
  Volume: 6 Issue: 47 Pages: 31595-31604
- DOI
  10.1021/acsomega.1c04074
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-21K19040, KAKENHI-PROJECT-20H02863
[Journal Article] [2] Raman spectra of acetylene-tagged anthraquinone derivatives in various solvents2021
- Author(s)
  Makanai, H.; Nishihara, T.; Tanabe, K.
- Journal Title
  
  Photomedicine and Photobiology
  
  Volume: 42 Pages: 17-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02863
[Journal Article] Monitoring intracellular metal ion complexation with acetylene-tagged ligand by Raman spectroscopy2020
- Author(s)
  Takemura, S.; Watanabe, H.; Nishihara, T.; Okamoto, A.; Tanabe, K.
- Journal Title
  
  RSC Adv.
  
  Volume: 10 Issue: 59 Pages: 36119-36123
- DOI
  10.1039/d0ra06329k
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-18H03931, KAKENHI-PROJECT-20H02863, KAKENHI-PROJECT-19K22245
[Journal Article] Modulation of cell membrane functionalization by aggregates of oligodeoxynucleotides containing alkyl chain-modified uridines.2020
- Author(s)
  Kainuma, R.; Motohashi, Y.; Nishihara, T.; Kurihara, R.; Tanabe, K.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 18 Issue: 28 Pages: 5406-5413
- DOI
  10.1039/d0ob00943a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02863
[Journal Article] Hybridizing Oligonucleotides with Hydrophobic Peptide Nucleic Acids Assists Their Cellular Uptake through Aggregate Formation.2020
- Author(s)
  Misu, S.; Kurihara, R.; Kaimuma, R.; Sato, R.; Nishihara, T.; Tanabe, K.
- Journal Title
  
  ChemBioChem.
  
  Volume: 21 Issue: 8 Pages: 1140-1143
- DOI
  10.1002/cbic.201900607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02863
[Journal Article] (71)Confined Singlet Oxygen in Mesoporous Silica Nanoparticles: Selective Photochemical Oxidation of Small Molecules in Living Cells.2016
- Author(s)
  Nakamura, T.; Son, A.; Umehara, Y.; Ito, T.; Kurihara, R.; Ikemura, Y.; Tanabe, K.
- Journal Title
  
  Bioconjugate Chem.
  
  Volume: 27 Issue: 4 Pages: 1058-1066
- DOI
  10.1021/acs.bioconjchem.6b00061
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26288078, KAKENHI-PROJECT-26860103
[Journal Article] (72)Preparation of alkyne-labeled 2-nitroimidazoles　for identification of tumor hypoxia by Raman spectroscopy.2016
- Author(s)
  Kurihara, R.; Ikemura, Y.; Tanabe, K.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 26 Issue: 20 Pages: 4892-4894
- DOI
  10.1016/j.bmcl.2016.09.024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26288078, KAKENHI-PROJECT-26860103
[Journal Article] Controlling Localization and Excretion of Nanoparticles by Click Modification of the Surface Chemical Structures inside Living Cells2015
- Author(s)
  Takeo Ito, Takuma Nakamura, Eriko Kusaka, Ryohsuke Kurihara, Kazuhito Tanabe
- Journal Title
  
  ChemPlusChem
  
  Volume: 80 Issue: 5 Pages: 796-799
- DOI
  10.1002/cplu.201402436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860103, KAKENHI-PROJECT-26288078
[Journal Article] Water-soluble phosphorescent ruthenium complex with a fluorescent coumarin unit for ratiometric sensing of oxygen levels in living cells.2015
- Author(s)
  Hara, D.; Komatsu, H.; Son, A.; Nishimoto, S.; Tanabe, K.
- Journal Title
  
  Bioconjugate Chem.
  
  Volume: 26 Pages: 645-649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26560446
[Journal Article] Phosphorescent Ruthenium Complexes with Nitroimidazole Unit that Image Oxygen Fluctuation in Tumor Tissue2015
- Author(s)
  Son, A.; Kawasaki, A.; Hara, D.; Ito, T.; Tanabe, K.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 21 Issue: 6 Pages: 2527-2536
- DOI
  10.1002/chem.201404979
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26560446, KAKENHI-PROJECT-26288078
[Journal Article] Water-soluble phosphorescent ruthenium complex with a fluorescent coumarin unit for ratiometric sensing of oxygen levels in living cells.2015
- Author(s)
  Hara, D.; Komatsu, H.; Son, A.; Nishimoto, S.; Tanabe, K.
- Journal Title
  
  Bioconjugate Chem.
  
  Volume: 26 Issue: 4 Pages: 645-649
- DOI
  10.1021/acs.bioconjchem.5b00093
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26288078
[Journal Article] Hypoxic X-irradiation as an external stimulus for conformational change of oligodeoxynucleotides that possess disulfide bond and regulation of DNAzyme function.2015
- Author(s)
  Tanabe, K.; Okada, K.; Sugiura, M.; Ito, T.; Nishimoto, S.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 25 Issue: 2 Pages: 310-312
- DOI
  10.1016/j.bmcl.2014.11.043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26560446, KAKENHI-PROJECT-26288078
[Journal Article] (64)Oligonucleotides with consecutive alkylated phosphate units: Aggregation characteristics and drug transport into living cells2014
- Author(s)
  Tanabe, K.; Ando, Y.; Hara, D.; Ito, T.; Nishimoto, S.
- Journal Title
  
  RSC advances
  
  Volume: 4 Pages: 13367-13370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26560446
[Journal Article] (64)Oligonucleotides with consecutive alkylated phosphate units: Aggregation characteristics and drug transport into living cells2014
- Author(s)
  Tanabe, K.; Ando, Y.; Hara, D.; Ito, T.; Nishimoto, S.
- Journal Title
  
  RSC advances
  
  Volume: 4 Pages: 13367-13370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26288078
[Journal Article] Ruthenium complexes with hydrophobic ligands that are key factors for optical imaging of physiological hypoxia2013
- Author(s)
  Komatsu, H.; Yoshihara, K.; Yamada, H.; Kimura, Y.; Son, A.; Nishimoto, S.; Tanabe, K.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 19
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23113508
[Journal Article] Radiolytic reduction characteristics of drug-encapsulating DNA aggregates possessing disulfide bond2012
- Author(s)
  Tanabe, K.; Asada, T.; Ito, T.; Nishimoto, S.
- Journal Title
  
  Bioconjugate Chem.
  
  Volume: 23 Pages: 1909-1914
- Data Source
  KAKENHI-PROJECT-23659020
[Journal Article] Reductive activation of 5-fluorodeoxyuridine prodrug possessing azide methyl group by hypoxic X-irradiation2012
- Author(s)
  Tanabe, K.; Ishizaki, J.; Ando, Y.; Ito, T.; Nishimoto, S.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 22
- NAID
  120003874273
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23113508
[Journal Article] Synthesis and One-Electron Reduction Characteristics of Radiation-Activated Prodrugs Possessing Two 5-Fluorodeoxyuridine Units2012
- Author(s)
  Tanabe, K.; Sugiura, M.; Ito, T.; Nishimoto, S.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 20
- NAID
  120004873607
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23113508
[Journal Article] Aggregate formation and radiolytic degradation of amphiphilic DNA block copolymer possessing disulfide bond2012
- Author(s)
  Tanabe, K.; Asada, T.; Nishimoto, S.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 22 Pages: 7045-7047
- NAID
  120004996208
- Data Source
  KAKENHI-PROJECT-23659020
[Journal Article] 13C-labeled indolequinone-DTPA-Gd conjugate for NMR probing cytochrome : P450 reductase-mediated one-electron reduction2011
- Author(s)
  Komatsu, H.; Tanabe, K.; Nishimoto, S.
- Journal Title
  
  Bioorg.Med.Chem.Lett.
  
  Volume: 21 Issue: 2 Pages: 790-793
- DOI
  10.1016/j.bmcl.2010.11.105
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23113508
[Journal Article] Radiolytic Reduction Characteristics of Artificial Oligodeoxynucleotides Possessing 2-Oxoalkyl Group or Disulfide Bonds2011
- Author(s)
  Tanabe, K.; Ito, T.; Nishimoto, S.
- Journal Title
  
  J. Nucleic Acids
- Data Source
  KAKENHI-PROJECT-23659020
[Journal Article] Fluorescent labeling of oligodeoxynucleotides at phosphate group by click reaction2011
- Author(s)
  Tanabe, K.; Ando, Y.; Nishimoto, S.
- Journal Title
  
  Photomedicine and Photobiology
  
  Volume: 33 Pages: 48-49
- Data Source
  KAKENHI-PUBLICLY-23113508
[Journal Article] Preparation and Fluorescence Properties of Fluorophore-labeled Avidin-biotin System Immobilized on Fe_3O_4 Nanoparticles through Functional Indolequinone Linker2009
- Author(s)
  Hirata, N.; Tanabe, K.; Narita, A.; Tanaka, K.; Naka, K.; Chujo, Y.; Nishimoto, S.
- Journal Title
  
  Bioorg. Med. Chem. 17
  
  Pages: 3775-3781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750134
[Journal Article] Monitoring of biological one-electron reduction by ^<19>F-NMR using hypoxia selective activation of a ^<19>F-labeled indolequinone derivative2009
- Author(s)
  Tanabe, K.; Harada, H.; Narazaki, M.; Tanaka, K.; Inafuku, K.; Komatsu, H.; Ito, T.; Yamada, H.; Chujo, Y.; Matsuda, T.; Hiraoka, M.; Nishimoto, S.
- Journal Title
  
  J. Am. Chem. Soc. 131
  
  Pages: 15982-15983
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750134
[Journal Article] Radiolytic activation of cytarabine prodrug possessing 2-oxoalkyl group : one-electron reduction and2009
- Author(s)
  Hirata, N.; Fujisawa, Y.; Tanabe, K.; Harada, H.; Hiraoka, M.;
- Journal Title
  
  Org.Biomol.Chem 7
  
  Pages: 651-654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750134
[Journal Article] Monitoring of biological one-electron reduction by 19F-NMR using hypoxia selective activation of a 19F-labeled2009
- Author(s)
  Tanabe, K.; Harada, H.; Narazaki, M.; Tanaka, K.; Inafuku, K.;
- Journal Title
  
  J.Am.Chem.Soc. 131
  
  Pages: 15982-15983
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750134
[Journal Article] Photoelectrochemical identification of 5-methylcytosine modification in DNA: combination of photosensitization and enzymatic cleavage2009
- Author(s)
  Tanabe, K.; Yamada, H.; Ito, T.; Nishimoto, S.
- Journal Title
  
  Nucleic Acids Symp. Ser. 53
  
  Pages: 205-206
- Data Source
  KAKENHI-PROJECT-20750134
[Journal Article] DNA Hairpins Containing a Diaminostilbene Derivative as a Photo-induced Electron Donor for Probing the Effects of Single-Base Mismatches on Excess Electron Transfer in DNA2009
- Author(s)
  Takeo Ito、Aiko Hayashi、Akiko Kondo、Tsukasa Uchida、Kazuhito Tanabe、Hisatsugu Yamada、Sei-ichi Nishimoto
- Journal Title
  
  Org. Lett. 11
  
  Pages: 927-930
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750009
[Journal Article] Radiolytic activation of cytarabine prodrug possessing 2-oxoalkyl group: one-electron reduction and cytotoxicity characteristics2009
- Author(s)
  Hirata, N.; Fujisawa, Y.; Tanabe, K.; Harada, H.; Hiraoka, M.; Nishimoto, S.
- Journal Title
  
  Org. Biomol. Chem. 7
  
  Pages: 651-654
- NAID
  120001624118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750134
[Journal Article] Photoelectrochemical identification of 5-methylcytosine modificationin DNA : combination of photosensitization and enzymatic-cleavage2009
- Author(s)
  Kazuhito Tanabe, et al.
- Journal Title
  
  Nucleic Acids Symposium Series VOL.53
  
  Pages: 205-206
- Data Source
  KAKENHI-PROJECT-20750009
[Journal Article] Efficient photooxidative strand cleavage at 5-methylcytosine in DNA by sensitization with 9, 10-anthraquinone-tethered oligonucleotides2009
- Author(s)
  Yamada, H.; Kitauchi, Y.; Tanabe, K.; Ito, T.; Nishimoto, S.
- Journal Title
  
  Nucleic Acids Symp. Ser. 53
  
  Pages: 209-210
- Data Source
  KAKENHI-PROJECT-20750134
[Journal Article] Preparation and Fluorescence Properties of Fluorophore-labeled Avidin-biotin System Immobilized on Fe3O42009
- Author(s)
  Hirata, N.; Tanabe, K.; Narita, A.; Tanaka, K.; Naka, K.; Chujo
- Journal Title
  
  Bioorg.Med.Chem. 17
  
  Pages: 3775-3781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750134
[Journal Article] Pathways of Excess Electron Transfer in Phenothiazine-tethered DNA Containing Single-base Mismatches2009
- Author(s)
  Takeo Ito、Akiko Kondo、Tomoyuki Kamashita、Kazuhito Tanabe、Hisatsugu Yamada、Sei-ichi Nishimoto
- Journal Title
  
  Org. Biomol. Chem. 7
  
  Pages: 2077-2081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750009
[Journal Article] Radiation-and photo-induced activation of 5-fluorouracil prodrugs as strategy for the selective2008
- Author(s)
  Ito, T.; Tanabe, K.; Yamada, H. Hatta, H.; Nishimoto, S.
- Journal Title
  
  molecules 13
  
  Pages: 2370-2384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750134
[Journal Article] Radiation- and photo-induced activation of 5-fluorouracil prodrugs as a strategy for the selective treatment of solid tumors2008
- Author(s)
  Ito, T.; Tanabe, K.; Yamada, H.; Hatta, H.; Nishimoto, S.
- Journal Title
  
  molecules 13
  
  Pages: 2370-2384
- NAID
  120001462592
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750134
[Journal Article] The pH effect on the naphthoquinone-photosensitized oxidation of 5-methylcytosine2008
- Author(s)
  Yamada, H.; Tanabe, K.; Ito, T.; Nishimoto, S.
- Journal Title
  
  Chem. Eur. J. 14
  
  Pages: 10453-10461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750134
[Journal Article] Fluorometric identification of 5-methylcytosine modification in DNA: combination of photosensitized oxidation and invasive cleavage2008
- Author(s)
  Yamada, H.; Tanabe, K.; Nishimoto, S.
- Journal Title
  
  Bioconjugate Chem. 19
  
  Pages: 20-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750134
[Journal Article] Radiolytic one-electron reduction characteristics of tyrosine derivative caged by 2-oxopropyl group2008
- Author(s)
  Tanabe, K.; Ebihara, M.; Hirata, N.; Nishimoto, S.
- Journal Title
  
  Bioorg. Med. Chem. Lett. 18
  
  Pages: 6126-6129
- NAID
  120001624120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750134
[Journal Article] Photoelectrochemical evaluation of pH effect on hole transport through triplex-forming DNA immobilized on a gold electrode2008
- Author(s)
  Haruna, K.; Iida, H.; Tanabe, K.; Nishimoto, S.
- Journal Title
  
  Org. Biomol. Chem. 6
  
  Pages: 1613-1617
- NAID
  120001624119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750134
[Journal Article] Photocurrent response after enzymatic treatment of DNA duplexes immobilized on gold electrodes: electrochemical2008
- Author(s)
  Yamada, H.; Tanabe, K.; Nishimoto, S.
- Journal Title
  
  Org. Biomol. Chem. 6
  
  Pages: 272-277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015030
[Journal Article] Emission in hypoxia: one-electron reduction and fluorescence characteristics of indolequinone-coumarin2008
- Author(s)
  Tanabe, K.; Hirata, N.; Harada, H.; Hiraoka, M.; Nishimoto, S.
- Journal Title
  
  Chem Bio Chem. 9
  
  Pages: 426-432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015030
[Journal Article] The pH effect on the naphthoquinone-photosensitized oxidation of 5-methylcytosine2008
- Author(s)
  Yamada, H.; Tanabe, K. Ito, T.; Nishimoto, S.
- Journal Title
  
  Chem. Eur. J. 14
  
  Pages: 10453-10461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750134
[Journal Article] One-Electron reductive template-directed ligation of oligodeoxynucleotides possessing disulfide bond2008
- Author(s)
  Tanabe, K.; Kuraseko, E.; Yamamoto, Y.; Nishimoto, S.
- Journal Title
  
  J. Am. Chem. Soc. 130
  
  Pages: 6302-6303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750134
[Journal Article] One-Electron reductive template-directed ligation of oligodeoxynucleotides possessing disulfide bond2008
- Author(s)
  Tanabe, K.; Kuraseko, Yamamoto, Y.; Nishimoto, S.
- Journal Title
  
  J. Am. Chem. Soc. 130
  
  Pages: 6302-6303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750134
[Journal Article] Site-selective strand cleavage at methylated cytosine: regional effect of naphthoquinone chromophore on the2007
- Author(s)
  Yamada, H.; Tanabe, K.; Nishimoto, S.
- Journal Title
  
  Nucleic Acids Symp. Ser. 51
  
  Pages: 219-220
- Data Source
  KAKENHI-PROJECT-18015030
[Journal Article] 2-Oxoalkyl caged oligonucleotides : one-electron reductive activation into emergence of ordinary hybridization2007
- Author(s)
  Tanabe, K., Kanezaki, H., Ishii, H., Nishimoto, S.
- Journal Title
  
  Org.Biomol.Chem. 5
  
  Pages: 1242-1246
- Data Source
  KAKENHI-PROJECT-18015030
[Journal Article] Radiation-induced one-electron reduction of oligodeoxynucleotides possessing disulfide bond2007
- Author(s)
  Kuraseko E.; Tanabe, K.; Nishimoto, S.
- Journal Title
  
  Nucleic Acids Symp. Ser. 51
  
  Pages: 223-224
- Data Source
  KAKENHI-PROJECT-18015030
[Journal Article] 2-Oxoalkyl caged oligonucleotides : one-electron reductive activation into emergence of ordinary hybridization2007
- Author(s)
  Tanabe, K., Kanezaki, H., Ishii, H., Nishimoto, S.
- Journal Title
  
  Org.Biomol.Chem. 5
  
  Pages: 1242-1246
- Data Source
  KAKENHI-PROJECT-17710099
[Journal Article] One-electron photooxidation and site-selective strand cleavage at 5-methylcytosine in DNA by sensitization2007
- Author(s)
  Tanabe, K.; Yamada, H.; Nishimoto, S.
- Journal Title
  
  J. Am. Chem. Soc. 129
  
  Pages: 8034-8040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015030
[Journal Article] Current molecular design of intelligent drugs and imaging probes targeting tumor-specific microenvironment2007
- Author(s)
  Tanabe, K.; Zhang, Z.; Ito, T.; Hatta, H.; Nishimoto, S.
- Journal Title
  
  Org. Biomol. Chem. 5
  
  Pages: 3745-3757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015030
[Journal Article] Photo-induced release of fluorescent probe in the presence of target DNA : synergetic effect of two types of2006
- Author(s)
  Tanabe, K., Tachi, Y., Okazaki, A., Nishimoto, S.
- Journal Title
  
  Chem.Lett. 35
  
  Pages: 938-939
- Data Source
  KAKENHI-PROJECT-17710099
[Journal Article] Sensitive discrimination between cytosine and 5-methylcytosine in DNA by a modified invader method2006
- Author(s)
  Yamada, H., Tanabe, K., Nishimoto, S.
- Journal Title
  
  Nucleic Acids Symp.Ser. 50
  
  Pages: 163-164
- Data Source
  KAKENHI-PROJECT-18015030
[Journal Article] Effects of structural modification on the DNA binding properties and photo-induced cleavage reactivity of2006
- Author(s)
  Haruna, K., Kanezaki, H., Tanabe, K., Dai, W.-M., Nishimoto, S.
- Journal Title
  
  Bioorg.Med.Chem. 14
  
  Pages: 4427-4432
- Data Source
  KAKENHI-PROJECT-17710099
[Journal Article] Electrochemical evaluation of alternating duplex-triplex conversion effect on the anthraquinone-photoinjected hole transport through DNA duplex immobilized on a gold electrode2006
- Author(s)
  Tanabe, K., Iida, H., Haruna, K., Kamei, T., Okamoto, A., Nishimoto, S.
- Journal Title
  
  J.Am.Chem.Soc. 128
  
  Pages: 692-693
- Data Source
  KAKENHI-PROJECT-17019037
[Journal Article] Regulation of DNA duplex formation by hypoxic irradiation : one-electron reduction characteristics of2006
- Author(s)
  Tanabe, K., Kanezaki, H., Hirata, N., Goto, M., Nishimoto, S.
- Journal Title
  
  Nucleic Acids Symp.Ser. 50
  
  Pages: 83-84
- Data Source
  KAKENHI-PROJECT-18015030
[Journal Article] Regulation of DNA duplex formation by hypoxic irradiation : one-electron reduction'characteristics of2006
- Author(s)
  Tanabe, K., Kanezaki, H., Hirata, N., Goto, M., Nishimoto, S.
- Journal Title
  
  Nucleic Acids Symp.Ser. 50
  
  Pages: 83-84
- Data Source
  KAKENHI-PROJECT-17710099
[Journal Article] Sensitive discrimination between cytosine and 5-methylcytosine in DNA by a modified invader method2006
- Author(s)
  Yamada, H., Tanabe, K., Nishimoto, S.
- Journal Title
  
  Nucleic Acids Symp.Ser. 50
  
  Pages: 163-164
- Data Source
  KAKENHI-PROJECT-17710099
[Journal Article] Electrochemical evaluation of alternating duplex-triplex conversion effect on the anthraquinone-photoinjected hole transport through DNA duplex immobilized on a gold electrode2006
- Author(s)
  Tanabe, K., Iida, H., Haruna, K., Kamei, T., Okamoto, A., Nishimoto, S.
- Journal Title
  
  J.Am.Chem.Soc. 128
  
  Pages: 692-693
- Data Source
  KAKENHI-PROJECT-17710099
[Journal Article] Synthesis and DNA cleavage reaction characteristics of enediyne prodrugs activated via an allylic rearrangement2006
- Author(s)
  Tachi, Y., Dai, W.-M., Tanabe, K., Nishimoto, S.
- Journal Title
  
  Bioorg.Med.Chem 14
  
  Pages: 3199-3209
- Data Source
  KAKENHI-PROJECT-18015030
[Journal Article] Synthesis and DNA cleavage reaction characteristics of enediyne prodrugs activated via an allylic rearrangement2006
- Author(s)
  Tachi, Y., Dai, W.-M., Tanabe, K., Nishimoto, S.
- Journal Title
  
  Bioorg.Med.Chem 14
  
  Pages: 3199-3209
- Data Source
  KAKENHI-PROJECT-17710099
[Journal Article] Synthesis and DNA cleavage reaction characteristics of enediyne prodrugs activated via an allylic rearrangement by base or UV irradiation2006
- Author(s)
  Tachi, Y., Dai, W.-M., Tanabe, K., Nishimoto, S.
- Journal Title
  
  Bioorg.Med.Chem. (印刷中)
- Data Source
  KAKENHI-PROJECT-17019037
[Journal Article] Photo-induced release of fluorescent probe in the presence of target DNA : synergetic effect of two types of2006
- Author(s)
  Tanabe, K., Tachi, Y., Okazaki, A., Nishimoto, S.
- Journal Title
  
  Chem.Lett. 35
  
  Pages: 938-939
- Data Source
  KAKENHI-PROJECT-18015030
[Journal Article] Effects of structural modification on the DNA binding properties and photo-induced cleavage reactivity of2006
- Author(s)
  Haruna, K., Kanezaki, H., Tanabe, K., Dai, W.-M., Nishimoto, S.
- Journal Title
  
  Bioorg.Med.Chem. 14
  
  Pages: 4427-4432
- Data Source
  KAKENHI-PROJECT-18015030
[Journal Article] Synthesis and DNA cleavage reaction characteristics of enediyne prodrugs activated via an allylic rearrangement by base or UV irradiation2006
- Author(s)
  Tachi, Y., Dai, W.-M., Tanabe, K., Nishimoto, S.
- Journal Title
  
  Bioorg.Med.Chem. (印刷中)
- Data Source
  KAKENHI-PROJECT-17710099
[Journal Article] Switching of charge transport in DNA by regulated triplex formations at the dual sites2005
- Author(s)
  Haruna, K., Tanabe, K., Iida, H., Nishimoto, S.
- Journal Title
  
  Nucleic Acids Symp.Ser 49
  
  Pages: 147-148
- Data Source
  KAKENHI-PROJECT-17019037
[Journal Article] Switching of charge transport in DNA by regulated triplex formations at the dual sites2005
- Author(s)
  Haruna, K., Tanabe, K., Iida, H., Nishimoto, S.
- Journal Title
  
  Nucleic Acids Symp.Ser. 49
  
  Pages: 147-148
- Data Source
  KAKENHI-PROJECT-17710099
[Journal Article] A new class of 5-fluorouridine prodrug conjugated with tumor homing cyclic peptide CNGRC by ester linkers : Synthesis, reactivity and tumor-cell selective cytotocicity2005
- Author(s)
  Z.Zhang, H.Hatta, K.Tanabe, S.Nishimoto
- Journal Title
  
  Pharmaceutical Research 3
  
  Pages: 381-389
- Data Source
  KAKENHI-PROJECT-15750142
[Journal Article] Modulated drug release from the stem-and-loop structured oligodeoxynucleotide upon UV -A irradiation in the presence of target DNA2005
- Author(s)
  Tanabe, K., Nakata, H., Mukai S., Nishimoto, S.
- Journal Title
  
  Org.Biomol.Chem. 3
  
  Pages: 3893-3897
- Data Source
  KAKENHI-PROJECT-17710099
[Journal Article] Modulated drug release from the stem-and-loop structured oligodeoxynucleotide upon UV-A irradiation in the presence of target DNA2005
- Author(s)
  Tanabe, K., Nakata, H., Mukai S., Nishimoto, S.
- Journal Title
  
  Org.Biomol.Chem. 3
  
  Pages: 3893-3897
- Data Source
  KAKENHI-PROJECT-17019037
[Journal Article] Bioreduction activated prodrugs of camptothecin : molecular design, synthesis, activation mechanism and hypoxia selective cytotoxicity2005
- Author(s)
  Zhang, Z., Tanabe, K., Hatta, H., Nishimoto, S.
- Journal Title
  
  Org.Biomol.Chem. 3
  
  Pages: 1905-1910
- Data Source
  KAKENHI-PROJECT-17710099
[Journal Article] Bioreduction activated prodrugs of camptothecin : molecular design, synthesis, activation mechanism and hypoxia selective cytotoxicity2005
- Author(s)
  Zhang, Z., Tanabe, K., Hatta, H., Nishimoto, S.
- Journal Title
  
  Org.Biomol.Chem. 3
  
  Pages: 1905-1910
- Data Source
  KAKENHI-PROJECT-17019037
[Journal Article] Detection of 5-methylcytosine in DNA by photo-functionalized oligodeoxynucleotides possessing 2-methyl-1,4-naphthoquinone chromophore2005
- Author(s)
  Yamada, H., Tanabe, K., Nishimoto, S.
- Journal Title
  
  Nucleic Acids Symp.Ser 49
  
  Pages: 149-150
- Data Source
  KAKENHI-PROJECT-17019037
[Journal Article] Detection of 5-methylcytosine in DNA by photo-functionalized oligodeoxynucleotides possessing 2-methyl-1,4-naphthoquinone chromophore2005
- Author(s)
  Yamada, H., Tanabe, K., Nishimoto, S.
- Journal Title
  
  Nucleic Acids Symp.Ser. 49
  
  Pages: 149-150
- Data Source
  KAKENHI-PROJECT-17710099
[Journal Article] Cleavage at 5-methylcytosine in DNA by photosensitized oxidation with 2-methyl-1,4-naphthoquinone tethered oligodeoxynucleotides2005
- Author(s)
  H.Yamada, K.Tanabe, S.Nishimoto
- Journal Title
  
  Bioorg.Med.Chem.Lett. 15
  
  Pages: 665-668
- Data Source
  KAKENHI-PROJECT-15750142
[Journal Article] Drug release from funcutionalized oligodeoxynucleotide by photo-induced electron transfer2004
- Author(s)
  Y.Tachi, A.Okazaki, K.Tanabe, H.Hatta, S.Nishimoto
- Journal Title
  
  Nucleic Acids Symp.Ser. 48
  
  Pages: 79-80
- Data Source
  KAKENHI-PROJECT-15750142
[Journal Article] Propargylic sulfones possessing a 2-nitroimidazole function : Novel hypoxic-cell radiosensitizers with intracellular non-protein thiol depletion ability2004
- Author(s)
  K.Tanabe, R.Kojima, H.Hatta, S.Nishimoto
- Journal Title
  
  Bioorg.Med.Chem.Lett. 14
  
  Pages: 2633-2635
- Data Source
  KAKENHI-PROJECT-15750142
[Journal Article] Aminopeptidase N/CD13 targeting fluorescent probes : synthesis and application to tumor cell imaging
- Author(s)
  Z.Zhang, H.Harada, K.Tanabe, H.Hatta, M.Hiraoka, S.Nishimoto
- Journal Title
  
  Peptides (印刷中)
- Data Source
  KAKENHI-PROJECT-15750142
[Journal Article] Hypoxia-Selective activation of 5-fluorodeoxyuridine prodrug possessing indolequinone structure : Radiolytic reduction and cytotoxicity characeristics
- Author(s)
  K.Tanabe, Y.Makimura, Y.Tachi, A.Imagawa-Sato, S.Nishimoto
- Journal Title
  
  Bioorg.Med.Chem.Lett. (印刷中)
- Data Source
  KAKENHI-PROJECT-15750142
[Presentation] 19F元素を導入したニトロイミダゾール誘導体による低酸素環境のNMRによる可視化2023
- Author(s)
  小笹達也・西原達哉・田邉一仁
- Organizer
  第17回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-23K26779
[Presentation] アセチル基による修飾とラマンスペクトルを用いた核酸構造解析2023
- Author(s)
  田邉一仁
- Organizer
  第４５回日本光医学・光生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K26779
[Presentation] Regulation of photochemical 1O2 generation by conformational change of artificial oligodeoxynucleotides2023
- Author(s)
  Sae Harada, Tatsuya Nishihara, Kazuhito Tanabe
- Organizer
  The 50th International Symposium on Nucleic Acids Chemistry (ISNAC2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K26779
[Presentation] Development of Method for Preparing Protein-DNA Complexes Using Electrostatic Interaction2022
- Author(s)
  日髙綾太、西原達哉、田邉一仁
- Organizer
  第44回日本光医学・光生物学会
- Data Source
  KAKENHI-PROJECT-20H02863
[Presentation] フェニルボロン酸含有人工核酸を用いた代謝物解析手法の開発2022
- Author(s)
  本橋優人、西原達哉、田邉一仁
- Organizer
  第16回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-20H02863
[Presentation] Molecular Design of Functional Ruthenium Complexes that Visualize Tumor Hypoxia2022
- Author(s)
  田邉一仁
- Organizer
  日本薬学会第142年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H02863
[Presentation] SERS-Based detection of intracellular oligonucleotides by using acetylene-tagged Hoechst molecules.2021
- Author(s)
  Makanai, H.; Nishihara, T.; Tanabe, K.
- Organizer
  The 48th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02863
[Presentation] ラマンスペクトルを活用した核酸構造解析2021
- Author(s)
  田邉一仁
- Organizer
  第42回日本光医学・光生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H02863
[Presentation] Selective uptake of oligodeoxynucleotides into hypoxic cells: molecular design of modified nucleobase that was activated by nitroreductase.2021
- Author(s)
  Kikuchi, T.; Nishihara, T.; Tanabe, K.
- Organizer
  The 48th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02863
[Presentation] 腫瘍内低酸素環境の可視化に資する機能性ナノ粒子の設計2020
- Author(s)
  田邉一仁
- Organizer
  第63回日本放射線影響学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H02863
[Presentation] Ratiometric Sensing of Oxygen Status in Living Cells by Phosphorescent Ruthenium Complexes2016
- Author(s)
  Tanabe, K.; Hara, D.; Son, A.
- Organizer
  IUPAC Photochemistry
- Place of Presentation
  大阪
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26288078
[Presentation] Optical Imaging of Oxygen Fluctuation in Tumor Tissue by Ruthenium Complex-Tethered Oligonucleotides2016
- Author(s)
  Tanabe, K.; Yoshihara, K.; Takagi, K.
- Organizer
  22nd International Round Tables (Nucleic Acids)
- Place of Presentation
  Paris, France
- Year and Date
  2016-07-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26288078
[Presentation] Monitoring of oxygen levels in tumor tissue by phosphorescent ruthenium complexes with hydrophobic ligands2015
- Author(s)
  Kazuhito Tanabe
- Organizer
  The 7th Asia nad Oceania Conference of Photobiology
- Place of Presentation
  台湾
- Year and Date
  2015-11-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26560446
[Presentation] 少ないことを可視化する：低酸素可視化プローブの設計2015
- Author(s)
  田邉一仁
- Organizer
  青山学院大学物理・数理学科コロキウム
- Place of Presentation
  相模原市
- Year and Date
  2015-07-02
- Invited
- Data Source
  KAKENHI-PROJECT-26560446
[Presentation] Monitoring of oxygen levels in tumor tissue by phosphorescent ruthenium complexes with hydrophobic ligands2015
- Author(s)
  Kazuhito Tanabe
- Organizer
  The 7th Asia and Oceania Conference for Photobiology
- Place of Presentation
  台湾
- Year and Date
  2015-11-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26288078
[Presentation] Ｘ線照射下で駆動する生体関連材料を設計する2015
- Author(s)
  田邉一仁
- Organizer
  第２７回生体機能関連化学部会サマースクール
- Place of Presentation
  神戸市
- Year and Date
  2015-07-17
- Invited
- Data Source
  KAKENHI-PROJECT-26560446
[Presentation] 少ないことを可視化する：低酸素可視化プローブの設計2015
- Author(s)
  田邉一仁
- Organizer
  青山学院大学物理・数理学科コロキウム
- Place of Presentation
  相模原市
- Year and Date
  2015-07-02
- Invited
- Data Source
  KAKENHI-PROJECT-26288078
[Presentation] Phosphorescent ruthenium complexes for visualization of oxygen fluctuation in tumor cells2015
- Author(s)
  Kazuhito Tanabe
- Organizer
  International Conference on Nascent Developments in Chemical Sciences: Opportunities for Academia-Industry Collaboration
- Place of Presentation
  India
- Year and Date
  2015-10-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26288078
[Presentation] Ｘ線照射下で駆動する生体関連材料を設計する2015
- Author(s)
  田邉一仁
- Organizer
  第２７回生体機能関連化学部会サマースクール
- Place of Presentation
  神戸市
- Year and Date
  2015-07-17
- Invited
- Data Source
  KAKENHI-PROJECT-26288078
[Presentation] 低酸素細胞の可視化に向けた機能性分子のデザイン2013
- Author(s)
  田邉一仁
- Organizer
  第１４回癌治療増感研究シンポジウム
- Place of Presentation
  奈良
- Invited
- Data Source
  KAKENHI-PUBLICLY-23113508
[Presentation] ルテニウム錯体のDNAオリゴマーへの導入と低酸素イメージングへの応用2013
- Author(s)
  田邉一仁
- Organizer
  第93日本化学会春季年会
- Place of Presentation
  草津
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PUBLICLY-23113508
[Presentation] リン酸部にアルキン部を導入した人工核酸の機能2013
- Author(s)
  安藤雄一郎・西本清一・田邉一仁
- Organizer
  第93 日本化学会春季年会
- Place of Presentation
  立命館大学
- Data Source
  KAKENHI-PROJECT-23659020
[Presentation] リン酸部にアルキン部を導入した人工核酸の機能2013
- Author(s)
  安藤雄一郎・西本清一・田邉一仁
- Organizer
  第93日本化学会春季年会
- Place of Presentation
  草津
- Data Source
  KAKENHI-PROJECT-23659020
[Presentation] リン酸部にアルキン部位を持つＤＮＡの特性評価及びクリック反応による機能化2012
- Author(s)
  安藤雄一郎・西本清一・田邉一仁
- Organizer
  第6回バイオ関連化学シンポジウム
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659020
[Presentation] リン酸部にアルキン部位を持つ DNA の特性評価及びクリック反応による機能化2012
- Author(s)
  安藤雄一郎・西本清一・田邉一仁
- Organizer
  第6回バイオ関連化学シンポジウム
- Place of Presentation
  北海道大学
- Data Source
  KAKENHI-PROJECT-23659020
[Presentation] 低酸素細胞のリアルタイムイメージングに向けたルテニウム錯体の合成と評価12012
- Author(s)
  小松広和・芳原和希・石崎仁・田邉一仁・西本清一
- Organizer
  日本化学会春季年会
- Place of Presentation
  横浜
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PUBLICLY-23113508
[Presentation] 修飾ルテニウム錯体を用いた低酸素細胞のリアルタイムイメージング2012
- Author(s)
  田邉一仁
- Organizer
  第６回バイオ関連化学シンポジウム
- Place of Presentation
  札幌
- Year and Date
  2012-09-06
- Data Source
  KAKENHI-PUBLICLY-23113508
[Presentation] クマリン分子を導入したルテニウム錯体による低酸素細胞のレシオメトリックイメージング2012
- Author(s)
  田邉一仁・小松広和・西本清一
- Organizer
  がん治療増感研究シンポジウム
- Place of Presentation
  奈良
- Year and Date
  2012-02-10
- Data Source
  KAKENHI-PUBLICLY-23113508
[Presentation] X-ray sensitive nanosize drug carrier composed of DNA amphiphiles2011
- Author(s)
  浅田拓海・田邉一仁・西本清一
- Organizer
  国際核酸化学シンポジウム
- Place of Presentation
  北海道大学
- Data Source
  KAKENHI-PROJECT-23659020
[Presentation] X-ray sensitive nanosize drug carrier composed of DNA amiphiphiles2011
- Author(s)
  浅田拓海、田邉一仁、西本清一
- Organizer
  国際核酸化学シンポジウム
- Place of Presentation
  北海道大学（札幌）
- Data Source
  KAKENHI-PROJECT-23659020
[Presentation] 酸素濃度に可逆的に応答する分子プローブ開発:ルテニウム錯体の合成と機能2011
- Author(s)
  小松広和・芳原和希・原田浩・伊藤健雄・田邉一仁・平岡眞寛・西本清一
- Organizer
  バイオ関連化学シンポジウム
- Place of Presentation
  つくば
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PUBLICLY-23113508
[Presentation] Photoinduced electro transfer reaction in diaminostilbene- tethered DNA duplexes2009
- Author(s)
  Takeo Ito、Aiko Hayashi、Tsukasa Uchida、Tanabe Kazuhito、Hisatsugu Yamada、Sei-ichi Nishimoto
- Organizer
  The 6th International symposium on Nucleic Acids Chemistry
- Place of Presentation
  akayama、Gifu
- Year and Date
  2009-09-29
- Data Source
  KAKENHI-PROJECT-20750009
[Presentation] Photoelectrochemical identification of 5-methylcytosine modification in DNA : combination of photosensitization2009
- Author(s)
  Tanabe, K.; Yamada, H.; Ito, T.; Nishimoto, S.
- Organizer
  第6回国際核酸化学シンポジウム
- Place of Presentation
  高山市
- Year and Date
  2009-09-29
- Data Source
  KAKENHI-PROJECT-20750134
[Presentation] Efficient photooxidative strand cleavage at 5-methylcytosine in DNA by sensitization with 9.10-anthraquinone-tethered oligonucleotides2009
- Author(s)
  Kazuhito Tanabe
- Organizer
  The 6th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  高山市民文化会館(岐阜県)
- Year and Date
  2009-09-29
- Data Source
  KAKENHI-PROJECT-20750009
[Presentation] ジアミノスチルベンを含むDNAにおける電子移動反応の塩基配列依存性2009
- Author(s)
  内田吏、伊藤健雄、林亜衣子、田邉一仁、山田久嗣、西本清一
- Organizer
  第24回生体機能関連化学シンポジウム
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20750009
[Presentation] DNA中メチル化シトシンの電気化学的検出2008
- Author(s)
  田邉一仁・山田久嗣・西本清一
- Organizer
  第30回光医学・光生物学会
- Place of Presentation
  松江
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-20750134
[Presentation] pH effect on the one-electron photooxidation of 5-methylcytosine with naphthoquinone sensitizer2008
- Author(s)
  Yamada, H.; Tanabe, K.; Ito, T.; Nishimoto, S.
- Organizer
  35th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2008-09-11
- Data Source
  KAKENHI-PROJECT-20750134
[Presentation] Photoinduced excess electron injection into DNA duplexes containing mismatched base pairs2008
- Author(s)
  Takeo Ito、Akiko Kondo、Aiko Hayashi、Tsukasa Uchida、Kazuhito Tanabe、Sei-ichi Nishimoto
- Organizer
  Joint Symposium of 18th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids and 35th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-20750009
[Presentation] pH effect on the one-electron photooxidation of 5-methylcytosine with naphthoquinone sensitizer2008
- Author(s)
  Yamada, H.; Tanabe, K.; Ito, T.; Nishimoto, S.
- Organizer
  第35回核酸化学シンポジウム
- Place of Presentation
  京都
- Year and Date
  2008-09-11
- Data Source
  KAKENHI-PROJECT-20750134
[Presentation] 低酸素細胞をイメージングする分子システムの開発2007
- Author(s)
  田邊一仁・平田直・原田浩・平岡真寛・西本清一
- Organizer
  第29回日本光医学・光生物学会
- Place of Presentation
  富山
- Year and Date
  2007-07-13
- Data Source
  KAKENHI-PROJECT-18015030
[Presentation] 低酸素条件下X線照射により機能一発現するプロドラッグシステムの開発2007
- Author(s)
  田邊一仁・金崎浩・海老原雅彦・藤沢祐輔・平田直・西本清一
- Organizer
  第22回生体機能関連化学シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2007-09-29
- Data Source
  KAKENHI-PROJECT-18015030
[Presentation] Radiation-induced one-electron reduction of oligodeoxynucleotides possessing disulfide bond2007
- Author(s)
  倉世古絵美・田邊一仁・西本清一
- Organizer
  第5回国際核酸化学シンポジウム
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-18015030
[Presentation] Site-selective strand cleavage at methylated cytosine: regional effect of naphthoquinone chromophore on the2007
- Author(s)
  山田久嗣・田邊一仁・西本清一
- Organizer
  第5回国際核酸化学シンポジウム
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-18015030
[Presentation] Oligodeoxynucleotides Possessing Phosphorescent Ruthenium Complex for Monitoring of Oxygen Fluctuation in Tumor Tissue
- Author(s)
  Kazuhito Tanabe
- Organizer
  2014 Korea-Japan Symposium on Frontier Photoscience
- Place of Presentation
  韓国、ソウル
- Year and Date
  2014-06-21 – 2014-06-23
- Invited
- Data Source
  KAKENHI-PROJECT-26288078
[Presentation] ルテニウム錯体のりん光発光を活用した腫瘍内酸素濃度変動の可視化
- Author(s)
  田邉一仁、孫安生、川崎惇、芳原和希
- Organizer
  日本光医学光生物学会
- Place of Presentation
  大阪大学
- Year and Date
  2014-07-25 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-26288078
[Presentation] RUTHENIUM COMPLEXES WITH HYDROPHOBIC LIGANDS
- Author(s)
  Kazuhito Tanabe, Aoi Son, Atsuhi Kawasaki
- Organizer
  XXVth IUPAC on Photochemistry
- Place of Presentation
  フランス、ボルドー
- Year and Date
  2014-07-13 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-26288078
[Presentation] 放射線照射下で薬効を発現させる：放射線照射によって崩壊するドラッグキャリアの提案
- Author(s)
  田邉一仁
- Organizer
  癌治療増感研究シンポジウム
- Place of Presentation
  奈良
- Year and Date
  2015-02-06 – 2015-02-07
- Data Source
  KAKENHI-PROJECT-26560446

1. KAWAI KIYOHIKO (50314422)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. NISHIMOTO Sei-ichi (10115909)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. ITO Takeo (80378801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. YAMADA Hisatsugi (80512764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. SHIBAMOTO Yuta (20144719)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 孫安生 (30447924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. 西原達哉 (00773201)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
8. 丸山厚 (40190566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 岡本晃充

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 西川元也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 栗原亮介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tanabe Kazuhito 田邉 一仁

田邊 一仁 タナベ カズヒト

TANABE Kazuhito 田邉 一仁

Research Projects

Research Products

Co-Researchers

蛍光ブリンキング制御による細胞内粘度・拡散速度の超解像計測

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Integrated understanding and manipulation of hypoxic cellular functions by artificial nucleic acids with hypoxia-accumulating propertiesPrincipal Investigator

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Construction of RNA dynamics science and RNA-targeted drug assay systems

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Drug Design for Hypoxic TheranosticsPrincipal Investigator

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Evaluation of oxygen effect on radiolysis of tumor tissue on the basis of quantitative analysis of oxygen concentrationPrincipal Investigator

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Design of smart drugs that are activated upon X-irradiationPrincipal Investigator

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病的細胞の選択的可視化を指向した低酸素応答性蛍光プローブの開発Principal Investigator

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Design of X-ray responsive drug carriers composed of oligodeoxynucleotidesPrincipal Investigator

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Highly Efficient Excess Electron Transfer in Precisely Designed DNA Architectures

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Detection of 5-methylcytosine in DNA by functionalized oligodeoxynucleotidesPrincipal Investigator

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がんの放射線-化学併用療法を指向した放射線活性化型プロドラッグの開発Principal Investigator

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遺伝子配列識別能をもつ光活性化型ドラッグの開発Principal Investigator

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導電性のオン・オフ機能をもつDNAナノデバイスの開発Principal Investigator

Principal Investigator

Tanabe Kazuhito 田邉一仁

田邊一仁タナベカズヒト

TANABE Kazuhito 田邉一仁

[Book] 化学フロンティアゲノム化学-医学、分子生物学への応用と展開 (齋藤烈, 杉山弘, 中谷和彦編)2007

[Book] 化学フロンティアゲノム化学-医学、分子生物学への応心用と展開 (斎藤烈・杉山弘・中谷和彦編)2007

[Book] 蛋白質核酸酵素 2007年10月号増刊ケミカルバイオロジー2007