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Cui Dan  崔 丹

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CUI Dan  崔 丹

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Researcher Number 40346549
Other IDs
Affiliation (Current) 2025: 山口大学, 大学院医学系研究科, 准教授
Affiliation (based on the past Project Information) *help 2019 – 2024: 山口大学, 大学院医学系研究科, 准教授
2017 – 2018: 山口大学, 大学院医学系研究科, 講師
2015 – 2016: 山口大学, 医学(系)研究科(研究院), 講師
2011 – 2013: 山口大学, 医学(系)研究科(研究院), 講師
Review Section/Research Field
Principal Investigator
Basic Section 56010:Neurosurgery-related / Experimental pathology
Except Principal Investigator
Basic Section 49030:Experimental pathology-related / Experimental pathology
Keywords
Principal Investigator
低酸素 / NFATc4 / 低栄養 / 壊死周囲ニッチ / 膠芽腫治療戦略 / 腫瘍幹細胞 / 膠芽腫 / タイト結結合 / グローディン5 / クローディン5 / タイト結合 / 血液網膜関門 / 血液脳関門 … More
Except Principal Investigator
… More 炎症 / 低酸素 / 血液脳関門 / Basigin / Claudin-5 / 糖尿病網膜症 / 高マンノース型糖鎖 / 難治性神経疾患 / 脳血管内皮細胞 / クローディン / タイト結合 / 血管内皮細胞 / 脳梗塞 / メタロプロテアーゼ / claudin-5 Less
  • Research Projects

    (7 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (5 People)
  •  Basiginに焦点を当てた血液脳関門の人為的制御に基づく新規神経疾患治療法の開発

    • Principal Investigator
      池田 栄二
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Yamaguchi University
  •  NFATc4を主軸とした壊死周囲微小環境の攪乱に基づく新規膠芽腫治療戦略の開発Principal Investigator

    • Principal Investigator
      崔 丹
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Yamaguchi University
  •  Establishment of the procedure to regulate artificially the neural vascular barrier function for overcoming the intractability of neural diseases

    • Principal Investigator
      Ikeda Eiji
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Yamaguchi University
  •  Analysis of Cancer Stem Cell Induction Ability in the Microenvironment of Glioblastoma Focused on NFATc4Principal Investigator

    • Principal Investigator
      Cui Dan
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Yamaguchi University
  •  Establishment of new therapies for intractable neural diseases based on the artificial regulation of neural vascular barrier

    • Principal Investigator
      Ikeda Eiji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Yamaguchi University
  •  Regulation of blood-brain barrier function by membrane-type metalloproteinases

    • Principal Investigator
      IKEDA EIJI
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Yamaguchi University
  •  Elucidation of the regulatory mechanism for claudin-5 expression in vascular endothelial cellsPrincipal Investigator

    • Principal Investigator
      CUI Dan
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Yamaguchi University

All 2024 2023 2022 2021 2020 2016 2013 2012

All Journal Article Presentation Patent

  • [Journal Article] High-mannose-type glycan of basigin in endothelial cells is essential for the opening of blood-brain barrier induced by hypoxia, cyclophilin A or TNF-α2024

    • Author(s)
      Cui D, Yamamoto K, Ikeda E
    • Journal Title

      American Journal of Pathology

      Volume: 194 Issue: 4 Pages: 612-625

    • DOI

      10.1016/j.ajpath.2023.11.007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06949
  • [Journal Article] Basigin can be a therapeutic target to restore the retinal vascular barrier function in the mouse model of diabetic retinopathy.2016

    • Author(s)
      Arima, M., Cui, D., Kimura, T., Sonoda, K.H., Ishibashi, T., Matsuda, S., and Ikeda, E.
    • Journal Title

      Sci. Rep.

      Volume: 6 Issue: 1 Pages: 38445-38445

    • DOI

      10.1038/srep38445

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01164, KAKENHI-PROJECT-15K15157, KAKENHI-PROJECT-15K08424
  • [Patent] 神経疾患治療剤2013

    • Inventor(s)
      池田栄二、崔 丹
    • Industrial Property Rights Holder
      山口大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013
    • Data Source
      KAKENHI-PROJECT-23590447
  • [Patent] 神経疾患治療剤2013

    • Inventor(s)
      池田栄二、崔丹
    • Industrial Property Rights Holder
      山口大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-04-25
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23590447
  • [Presentation] 血液脳関門の人為的制御手法確立に向けた基礎研究2024

    • Author(s)
      崔 丹、森重 拓士、池田 栄二
    • Organizer
      第113回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-21K06949
  • [Presentation] 膠芽腫における静止期腫瘍幹細胞の誘導機序について2023

    • Author(s)
      崔丹、吉冨千尋、田中瑛、池田栄二
    • Organizer
      第112回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-21K09152
  • [Presentation] 高マンノース型basigin は血液脳関門の開口に関与する2023

    • Author(s)
      崔 丹、森重拓士、池田栄二
    • Organizer
      第112回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-21K06949
  • [Presentation] NFATc4によるヒト神経膠芽腫の壊死周囲ニッチにおける静止期幹細胞様の腫瘍細胞の誘導2022

    • Author(s)
      吉冨千尋、崔丹、田中瑛、河野裕夫、池田栄二
    • Organizer
      111回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-21K09152
  • [Presentation] 中枢神経系疾患における高マンノース型basigin の役割について2022

    • Author(s)
      崔 丹、池田 栄二
    • Organizer
      第111回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-21K06949
  • [Presentation] Cyclophilin A による神経系血管バリアーの人為的開口2021

    • Author(s)
      崔 丹、仲田ー本田成美、松田達志、池田栄二
    • Organizer
      第110回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-18K07044
  • [Presentation] 神経系血管バリアー機能異常と疾患2020

    • Author(s)
      池田栄二、崔 丹、白濱つづり、仲田成美
    • Organizer
      第109回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-18K07044
  • [Presentation] ADAM12 and ADAM17 are essential molecules for hypoxia-induced impairment of neural vascular barrier function.2016

    • Author(s)
      Ikeda E, Cui D, Arima M
    • Organizer
      Gordon Research Conference‘Barriers of the CNS’
    • Place of Presentation
      Colby-Sawyer College, New London, NH, USA
    • Year and Date
      2016-06-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08424
  • [Presentation] 血液脳関門の酸素濃度依存性調節機構2013

    • Author(s)
      池田栄二、崔丹
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      ロイトン札幌,(北海道)
    • Data Source
      KAKENHI-PROJECT-23590447
  • [Presentation] Deferoxamine刺激下の脳血管内皮細胞におけるclaudin-5発現解析2012

    • Author(s)
      岩本沙也加、崔丹、高橋睦夫、河野裕夫、池田栄二
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      京王プラザホテル(東京)
    • Data Source
      KAKENHI-PROJECT-23590447
  • [Presentation] Deferroxamine刺激下の脳血管内皮細胞におけるclaudin-5発現解析2012

    • Author(s)
      岩本沙也加、崔丹、高橋睦夫、河野裕夫、池田栄二
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      東京、京王プラザホテル
    • Data Source
      KAKENHI-PROJECT-23590447
  • 1.  IKEDA Eiji (30232177)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 12 results
  • 2.  田中 瑛 (60913936)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 3.  吉冨 千尋 (50819323)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 4.  森重 拓士 (70967207)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  松田 達志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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