ISHIKAWA Yuko 石川祐子

Researcher Number	40353940
Other IDs
Affiliation (Current)	2025: 国立研究開発法人農業・食品産業技術総合研究機構, 食品研究部門, 主任研究員
Affiliation (based on the past Project Information) *help	2021 – 2022: 国立研究開発法人農業・食品産業技術総合研究機構, 食品研究部門, 主席研究員 2018 – 2020: 国立研究開発法人農業・食品産業技術総合研究機構, 食品研究部門, ユニット長 2016: 国立研究開発法人農業・食品産業技術総合研究機構, 食品研究部門食品健康機能研究領域, ユニット長 2016: 国立研究開発法人農業・食品産業技術総合研究機構, 食品研究部門, 主席研究員 2015: 国立研究開発法人農業・食品産業技術総合研究機構, 食品研究部門・食品健康機能研究領域, ユニット長 … More 2015: 国立研究開発法人農業・食品産業技術総合研究機構, 食品研究部門食品健康機能研究領域, ユニット長 2014: 独立行政法人農業・食品産業技術総合研究機構, 食品総合研究所食品機能研究領域, 上席研究員 2014: 独立行政法人農業・食品産業技術総合研究機構, 食品総合研究所食品機能研究領域, 上席研究員 2011: 独立行政法人農業・食品産業技術総合研究機構, 食品総合研究所・食品機能研究領域, 上席研究員 2009 – 2010: National Agricultural Research Organization, 食品総合研究所食品機能研究領域, ユニット長 2009: 独立行政法人農業・食品産業技術総合研究機構, 食品総合研究所・食品機能研究領域・機能性成分解析ユニット, ユニット長 Less
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Food science Except Principal Investigator Basic Section 38050:Food sciences-related / Applied biochemistry
Keywords	Principal Investigator 加齢 / 免疫老化 / 免疫応答性 / フレイル / 生体内酸化・糖化ストレス / 代謝 / 一重項酸素消去能 / 酸素ラジカル吸収能 / 抗酸化物質 / 酸化ストレス … More / 炭水化物 / 栄養過多 / 栄養過剰 / 終末糖化産物 / 生体内酸化ストレス / 脂質・熱量摂取 / 免疫応答 / 脂質・摂取熱量 / アレルギー発症 / 摂取熱量 / 高ショ糖食 / 高脂肪食 / 熱量 / regT細胞 / Tfh細胞 / 感作 / 皮膚アナフィラキシー反応 / T細胞 / IgE / 抗原感作 / 経口免疫寛容 / アレルギー … More Except Principal Investigator 食品 / 筋萎縮 / 終末糖化産物 / IgA / 腸管免疫 / 恒常性 / 抗原特異性 / 腸管IgA / 食品成分 / 細胞・組織 / ストレス / タンパク質 / 脂質 / シグナル伝達 / 細胞･組織 / LOX1 / 酸化LDL受容体 / 酸化LDL / 競合ELISA / ビオチン化 / サンドイッチELISA / オリゴマー化 / LOX-1 Less

終末糖化産物受容体の機能を抑制しうる食品成分の探索と効果検証
- Principal Investigator
  
  小堀俊郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  National Agriculture and Food Research Organization
加齢がもたらす生体内酸化・糖化ストレスを食により低減し、慢性炎症を予防するPrincipal Investigator
- Principal Investigator
  
  石川祐子
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  National Agriculture and Food Research Organization
The effects of diet on the production of T-dependent and T-independent secretory IgA
- Principal Investigator
  
  Goto Masao
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  National Agriculture and Food Research Organization
Elucidation of the effect of the oxidation stress on immunosenescence, exerting from nutritional metabolism or agingPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Yuko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  National Agriculture and Food Research Organization
血管内皮機能不全を誘導する細胞内代謝変動と遺伝子発現制御機構の解析
- Principal Investigator
  
  町田幸子
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied biochemistry
- Research Institution
  National Agriculture and Food Research Organization
Establishment of the next generation type Japanese food-style which considered calorie, fatty acid and PFC ratio, effective in immune-balance improvementPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Yuko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  National Agriculture and Food Research Organization
Oligomer forming mechanism of lectin-like oxidized LDL receptor-1(LOX-1), and its functional reconstitution.
- Principal Investigator
  
  MACHIDA Sachiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied biochemistry
- Research Institution
  National Agriculture and Food Research Organization
Analysis on mechanism of development of sensitization which decides symptom onset of allergic diseasePrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Yuko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  National Agriculture and Food Research Organization

All 2019 2012 2011 2010

All Journal Article Presentation Patent

[Journal Article] Effect of Lacto-N-biose I on the Antigen-specific Immune Responses of Splenocytes2012
- Author(s)
  Masao GOTO, Yuko TAKANO-ISHIKAWA, Mamoru NISHIMOTO and Motomitsu KITAOKA
- Journal Title
  
  Bioscience of Microbiota, Food and Health
  
  Volume: 31 Pages: 47-50
- NAID
  10030872794
- URL
  https://www.jstage.jst.go.jp/article/bmfh/31/2/31_2_47/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580167
[Journal Article] Identification of 4-hydroxy-2-nonenal-histidine adducts that serve as ligands for human lectin-like oxidized LDL receptor-12012
- Author(s)
  M. K. Kuramochi, Y. Shimozu, C. Wakita, M. O. Kameyama, T. Shibata, S. Matsunaga, Y. T. Ishikawa, J. Watanabe, M. Goto, Q. Xie, S. Komba, K. Uchida, S. Machida
- Journal Title
  
  The Biochemical Journal
  
  Volume: 442 Pages: 171-180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380068
[Journal Article] Effect of Lacto-N-biose 1 on the Antigen-specific Immnune Responses of Splenocytes2012
- Author(s)
  Masao GOTO, Yuko TAKANO-ISHIKAWA, Mamoru NISHIMOTO
- Journal Title
  
  Bioscience of Microbiota, Food and Health
  
  Volume: 31 Pages: 47-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580167
[Journal Article] Identification of 4-hydroxy-2-nonenal-histidine adducts that serve as ligands for human lectin-like oxidized LDL receptor-12012
- Author(s)
  Kumano-Kuramochi, M., Shimozu, Y., Wakita, C., Ohnishi-Kameyama, M., Shibata, T., Matsunaga, S., Takano-Ishikawa, Y., Watanabe, J., Goto, M., Xie, Q., Komba, S., Uchida, K., and Machida, S.
- Journal Title
  
  Biochem. J
  
  Volume: 442 Issue: 1 Pages: 171-180
- DOI
  10.1042/bj20111029
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117007, KAKENHI-PROJECT-21248016, KAKENHI-PROJECT-21380068, KAKENHI-PROJECT-22780107
[Journal Article] Effect of caffeine on antigen-specific immune responses of mouse splenocytes2011
- Author(s)
  Masao Goto, Yuko Takano-Ishikawa, Hiroshi Shinmoto
- Journal Title
  
  食総研報
  
  Volume: 75 Pages: 17-23
- NAID
  120006773511
- URL
  http://www.naro.affrc.go.jp/publicity_report/publication/files/75_hokoku_p017-023.pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580167
[Patent] 免疫抑制剤2011
- Inventor(s)
  福留真一、田中啓子、石川祐子、後藤真生、渡辺純
- Industrial Property Rights Holder
  福留真一、田中啓子、石川祐子、後藤真生、渡辺純
- Filing Date
  2011-10-25
- Data Source
  KAKENHI-PROJECT-21580167
[Patent] 免疫抑制剤2011
- Inventor(s)
  福留真一、田中啓子、石川祐子、後藤真生、渡辺純
- Industrial Property Rights Holder
  福留真一、田中啓子、石川祐子、後藤真生、渡辺純
- Filing Date
  2011-10-25
- Data Source
  KAKENHI-PROJECT-21580167
[Patent] リガンド様活性を有する分子の検出法法2010
- Inventor(s)
  町田幸子、倉持みゆき、石川祐子、後藤真生、渡辺純
- Industrial Property Rights Holder
  独立行政法人農業・食品産業技術総合研究機構
- Industrial Property Number
  2010-025840
- Filing Date
  2010-11-18
- Data Source
  KAKENHI-PROJECT-21380068
[Patent] リガンド様活性を有する分子の検出方法2010
- Inventor(s)
  町田幸子、倉持みゆき、石川祐子、後藤真生、渡辺純
- Industrial Property Rights Holder
  農研機構
- Industrial Property Number
  2010-025840
- Filing Date
  2010-11-18
- Data Source
  KAKENHI-PROJECT-21380068
[Presentation] The effects of diet on the production of T-dependent and T-independent secretory IgA2019
- Author(s)
  M.Goto, M.Wakagi, Y. Takano-Ishikawa
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-19K05906
[Presentation] 腸管IgAが摂取食品から受ける影響は、その抗原特異性により異なる2019
- Author(s)
  後藤真生，若木学，石川（高野）祐子
- Organizer
  日本食品免疫学会
- Data Source
  KAKENHI-PROJECT-19K05906
[Presentation] 食物アレルギー状態における免疫細胞の細胞表面分子の解析2011
- Author(s)
  後藤真生・渡辺純・石川(高野)祐子
- Organizer
  日本食品免疫学会2011年度大会
- Place of Presentation
  東京大学安田講堂
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-21580167
[Presentation] 食物アレルギー状態における免疫細胞の表現系解析2011
- Author(s)
  後藤真生・渡辺純・石川(高野)祐子
- Organizer
  日本農芸化学会2010年度大会(要旨集)
- Place of Presentation
  京都女子大学
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-21580167
[Presentation] 経口抗原投与による血清中IgEの誘導には投与期間内に投与休止期が必要である2010
- Author(s)
  後藤真生・渡辺純・石川(高野)祐子
- Organizer
  日本食品免疫学会2010年度大会
- Place of Presentation
  東京大学安田講堂
- Year and Date
  2010-06-02
- Data Source
  KAKENHI-PROJECT-21580167

1. GOTO Masao (30302590)

# of Collaborated Projects: 5 results

# of Collaborated Products: 8 results
2. 若木学 (50710878)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
3. MACHIDA Sachiko (30353981)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. WATANABE Jun (10374729)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 小堀俊郎 (10353971)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. YAMAKI Kohji (70174597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SHIBATA Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 内田浩二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ISHIKAWA Yuko 石川 祐子

Research Projects

Research Products

Co-Researchers

終末糖化産物受容体の機能を抑制しうる食品成分の探索と効果検証

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

加齢がもたらす生体内酸化・糖化ストレスを食により低減し、慢性炎症を予防するPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The effects of diet on the production of T-dependent and T-independent secretory IgA

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the effect of the oxidation stress on immunosenescence, exerting from nutritional metabolism or agingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

血管内皮機能不全を誘導する細胞内代謝変動と遺伝子発現制御機構の解析

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of the next generation type Japanese food-style which considered calorie, fatty acid and PFC ratio, effective in immune-balance improvementPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Oligomer forming mechanism of lectin-like oxidized LDL receptor-1(LOX-1), and its functional reconstitution.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis on mechanism of development of sensitization which decides symptom onset of allergic diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Effect of Lacto-N-biose I on the Antigen-specific Immune Responses of Splenocytes2012

Author(s)

Journal Title

NAID

URL

Data Source

[Journal Article] Identification of 4-hydroxy-2-nonenal-histidine adducts that serve as ligands for human lectin-like oxidized LDL receptor-12012

Author(s)

Journal Title

Data Source

[Journal Article] Effect of Lacto-N-biose 1 on the Antigen-specific Immnune Responses of Splenocytes2012

Author(s)

Journal Title

Data Source

[Journal Article] Identification of 4-hydroxy-2-nonenal-histidine adducts that serve as ligands for human lectin-like oxidized LDL receptor-12012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of caffeine on antigen-specific immune responses of mouse splenocytes2011

Author(s)

Journal Title

NAID

URL

Data Source

[Patent] 免疫抑制剤2011

Inventor(s)

Industrial Property Rights Holder

ISHIKAWA Yuko 石川祐子