KUWAYAMA Kenji 桑山健次

… Alternative Names

桑山健次クワヤマケンジ

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Researcher Number	40356233
Other IDs
Affiliation (Current)	2025: 科学警察研究所, 法科学第三部, 主任研究官
Affiliation (based on the past Project Information) *help	2014 – 2024: 科学警察研究所, 法科学第三部, 主任研究官 2010 – 2013: 科学警察研究所, 法科学第三部, 研究員 2009: National Research Institute of Police Science, 附属鑑定所, 研究員 2006 – 2007: 科学警察研究所, 附属鑑定所, 研究員
Review Section/Research Field	Principal Investigator Legal medicine / Basic Section 58040:Forensics medicine-related
Keywords	Principal Investigator 質量分析 / 毛髪 / 分析科学 / 薬学 / 社会医学 / 食品 / 薬 / 尿 / 質量分析計 / 睡眠薬 … More / 大量尿 / 薬物 / 指紋 / 薬物鑑定学 / 法医鑑定学 / MDMA / メタンフェタミン / 毒性 / 体内分布 / 乱用薬物 / イメージング質量分析 / 法中毒学 Less

食品成分を指標とした毛髪のマイクロ分画分析による薬物摂取履歴・人物像解析の高度化Principal Investigator
- Principal Investigator
  
  桑山健次
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58040:Forensics medicine-related
- Research Institution
  National Research Institute of Police Science
Development of advanced analytical method for detection of hypnotics in urine and hairPrincipal Investigator
- Principal Investigator
  
  桑山健次
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58040:Forensics medicine-related
- Research Institution
  National Research Institute of Police Science
Determination of drug intake day by micro-segmental hair analysisPrincipal Investigator
- Principal Investigator
  
  Kuwayama Kenji
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  National Research Institute of Police Science
Detection of drugs in fingerprints using highly sensitive mass spectrometers and elucidation of relationship between drug concentrations in body fluidsPrincipal Investigator
- Principal Investigator
  
  KUWAYAMA Kenji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Legal medicine
- Research Institution
  National Research Institute of Police Science
Evaluation of toxicity of drugs based on drug distributions in organs by imaging mass spectrometryPrincipal Investigator
- Principal Investigator
  
  KUWAYAMA Kenji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Legal medicine
- Research Institution
  National Research Institute of Police Science
MDMA等錠剤型乱用薬物中の含有成分の相互作用による代謝及び排泄への影響Principal Investigator
- Principal Investigator
  
  桑山健次
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Legal medicine
- Research Institution
  National Research Institute of Police Science

[Journal Article] Development of a method to evaluate the effects of external environments on drug stability in nails using micro‐segmental analysis2024
- Author(s)
  Kuwayama Kenji、Miyaguchi Hajime、Kanamori Tatsuyuki、Tsujikawa Kenji、Yamamuro Tadashi、Segawa Hiroki、Okada Yuki、Iwata Yuko T.
- Journal Title
  
  Drug Testing and Analysis
  
  Volume: - Issue: 2 Pages: 188-197
- DOI
  10.1002/dta.3698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10700
[Journal Article] Effects of temperature, humidity, light, and soil on drug stability in hair: a preliminary study for estimating personal profiles using micro-segmental analysis of corpse hair2023
- Author(s)
  Kuwayama Kenji、Miyaguchi Hajime、Kanamori Tatsuyuki、Tsujikawa Kenji、Yamamuro Tadashi、Segawa Hiroki、Okada Yuki、Iwata Yuko T.
- Journal Title
  
  Forensic Toxicology
  
  Volume: 42 Issue: 1 Pages: 60-70
- DOI
  10.1007/s11419-023-00675-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10700
[Journal Article] Evaluation of applicability of micro-segmental analysis to hair treated with heat and haircare products2023
- Author(s)
  Kuwayama Kenji、Miyaguchi Hajime、Kanamori Tatsuyuki、Tsujikawa Kenji、Yamamuro Tadashi、Segawa Hiroki、Okada Yuki、Iwata Yuko T.
- Journal Title
  
  Forensic Toxicology
  
  Volume: - Issue: 2 Pages: 260-271
- DOI
  10.1007/s11419-023-00663-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10700
[Journal Article] Micro-segmental hair analysis: detailed procedures and applications in forensic toxicology2022
- Author(s)
  Kuwayama Kenji、Miyaguchi Hajime、Kanamori Tatsuyuki、Tsujikawa Kenji、Yamamuro Tadashi、Segawa Hiroki、Okada Yuki、Iwata Yuko T.
- Journal Title
  
  Forensic Toxicology
  
  Volume: 40 Issue: 2 Pages: 215-233
- DOI
  10.1007/s11419-022-00619-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10700
[Journal Article] Distribution profiles of diphenhydramine and lidocaine in scalp, axillary, and pubic hairs measured by micro-segmental hair analysis: good indicator for discrimination between administration and external contamination of the drugs2022
- Author(s)
  Kuwayama Kenji、Miyaguchi Hajime、Kanamori Tatsuyuki、Tsujikawa Kenji、Yamamuro Tadashi、Segawa Hiroki、Okada Yuki、Iwata Yuko T.
- Journal Title
  
  Forensic Toxicology
  
  Volume: 40 Issue: 1 Pages: 64-74
- DOI
  10.1007/s11419-021-00590-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10700
[Journal Article] Possibility of drug-distribution measurement in the hair of drowned bodies: evaluation of drug stability in water-soaked hair using micro-segmental analysis2022
- Author(s)
  Kuwayama Kenji、Miyaguchi Hajime、Kanamori Tatsuyuki、Tsujikawa Kenji、Yamamuro Tadashi、Segawa Hiroki、Okada Yuki、Iwata Yuko T.
- Journal Title
  
  International Journal of Legal Medicine
  
  Volume: 137 Issue: 1 Pages: 89-98
- DOI
  10.1007/s00414-022-02900-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10700
[Journal Article] Development of an improved method to estimate the days of continuous drug ingestion, based on the micro‐segmental hair analysis2021
- Author(s)
  Kuwayama Kenji、Miyaguchi Hajime、Kanamori Tatsuyuki、Tsujikawa Kenji、Yamamuro Tadashi、Segawa Hiroki、Okada Yuki、Iwata Yuko T.
- Journal Title
  
  Drug Testing and Analysis
  
  Volume: 13 Issue: 7 Pages: 1295-1304
- DOI
  10.1002/dta.3025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10700
[Journal Article] 分析試料の正しい取り扱いかた　生体（毛髪）2020
- Author(s)
  桑山　健次
- Journal Title
  
  ぶんせき
  
  Volume: 2 Pages: 38-43
- NAID
  40022165101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10700
[Journal Article] Development of the “selective concentration” analytical method for drug-containing hair regions based on micro-segmental analysis to identify a trace amount of drug in hair: hair analysis following single-dose ingestion of midazolam2020
- Author(s)
  Kuwayama Kenji、Miyaguchi Hajime、Kanamori Tatsuyuki、Tsujikawa Kenji、Yamamuro Tadashi、Segawa Hiroki、Okada Yuki、Iwata Yuko T.
- Journal Title
  
  Forensic Toxicology
  
  Volume: 39 Issue: 1 Pages: 156-166
- DOI
  10.1007/s11419-020-00553-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10700
[Journal Article] Measurement of three-dimensional distributions of drugs in nails using liquid chromatography/tandem mass spectrometry after micro-segmentation to elucidate drug uptake routes2020
- Author(s)
  Kuwayama Kenji、Miyaguchi Hajime、Kanamori Tatsuyuki、Tsujikawa Kenji、Yamamuro Tadashi、Segawa Hiroki、Okada Yuki、Iwata Yuko T.
- Journal Title
  
  Analytica Chimica Acta
  
  Volume: 1108 Pages: 89-97
- DOI
  10.1016/j.aca.2020.02.050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10700, KAKENHI-PROJECT-15K08894
[Journal Article] Development of High-resolution Methods for the Analysis of Drug Distribution in Biological Tissue Samples and Their Applications2019
- Author(s)
  Kuwayama Kenji
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 139 Issue: 8 Pages: 1063-1070
- DOI
  10.1248/yakushi.19-00112
- NAID
  130007686243
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2019-08-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10700, KAKENHI-PROJECT-15K08894
[Journal Article] Strong evidence of drug-facilitated crimes by hair analysis using LC-MS/MS after micro-segmentation2019
- Author(s)
  Kuwayama Kenji、Miyaguchi Hajime、Iwata Yuko T.、Kanamori Tatsuyuki、Tsujikawa Kenji、Yamamuro Tadashi、Segawa Hiroki、Inoue Hiroyuki
- Journal Title
  
  Forensic Toxicology
  
  Volume: 37 Issue: 2 Pages: 480-487
- DOI
  10.1007/s11419-019-00472-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10700, KAKENHI-PROJECT-15K08894
[Journal Article] Estimation of day of death using micro-segmental hair analysis based on drug use history: a case of lidocaine use as a marker2018
- Author(s)
  Kuwayama Kenji、Nariai Maika、Miyaguchi Hajime、Iwata Yuko T.、Kanamori Tatsuyuki、Tsujikawa Kenji、Yamamuro Tadashi、Segawa Hiroki、Abe Hiroko、Iwase Hirotaro、Inoue Hiroyuki
- Journal Title
  
  International Journal of Legal Medicine
  
  Volume: 133 Issue: 1 Pages: 117-122
- DOI
  10.1007/s00414-018-1939-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08894
[Journal Article] Micro-segmental hair analysis for proving drug-facilitated crimes: Evidence that a victim ingested a sleeping aid, diphenhydramine, on a specific day2018
- Author(s)
  Kuwayama Kenji、Nariai Maika、Miyaguchi Hajime、Iwata Yuko T.、Kanamori Tatsuyuki、Tsujikawa Kenji、Yamamuro Tadashi、Segawa Hiroki、Abe Hiroko、Iwase Hirotaro、Inoue Hiroyuki
- Journal Title
  
  Forensic Science International
  
  Volume: 288 Pages: 23-28
- DOI
  10.1016/j.forsciint.2018.04.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08894
[Journal Article] Accurate Estimation of Drug Intake Day by Microsegmental Analysis of a Strand of Hair by Use of Internal Temporal Markers2018
- Author(s)
  Kuwayama Kenji、Nariai Maika、Miyaguchi Hajime、Iwata Yuko T.、Kanamori Tatsuyuki、Tsujikawa Kenji、Yamamuro Tadashi、Segawa Hiroki、Abe Hiroko、Iwase Hirotaro、Inoue Hiroyuki
- Journal Title
  
  The Journal of Applied Laboratory Medicine
  
  Volume: 3 Issue: 1 Pages: 37-47
- DOI
  10.1373/jalm.2017.025346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08894
[Journal Article] Enantioselective determination of ( R )-zopiclone and ( S )-zopiclone (eszopiclone) in human hair by micropulverized extraction and chiral liquid chromatography/high resolution mass spectrometry2017
- Author(s)
  Miyaguchi Hajime、Kuwayama Kenji
- Journal Title
  
  Journal of Chromatography A
  
  Volume: 1519 Pages: 55-63
- DOI
  10.1016/j.chroma.2017.08.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08894
[Journal Article] Different localizations of drugs simultaneously administered in a strand of hair by micro-segmental analysis2017
- Author(s)
  Kuwayama Kenji、Miyaguchi Hajime、Iwata Yuko T.、Kanamori Tatsuyuki、Tsujikawa Kenji、Yamamuro Tadashi、Segawa Hiroki、Inoue Hiroyuki
- Journal Title
  
  Drug Testing and Analysis
  
  Volume: 10 Issue: 4 Pages: 750-760
- DOI
  10.1002/dta.2259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08894
[Journal Article] Time-course measurements of drug concentrations in hair and toenails after single administrations of pharmaceutical products2016
- Author(s)
  Kenji Kuwayama, Hajime Miyaguchi, Yuko T. Iwata, Tatsuyuki Kanamori, Kenji Tsujikawa, Tadashi Yamamuro, Hiroki Segawa, Hiroyuki Inoue
- Journal Title
  
  Drug Testing and Analysis
  
  Volume: 印刷中 Issue: 4 Pages: 571-577
- DOI
  10.1002/dta.1991
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08894
[Journal Article] Three-step drug extraction from a single sub-millimeter segment of hair and nail to determine the exact day of drug intake2016
- Author(s)
  Kenji Kuwayama, Hajime Miyaguchi, Yuko T. Iwata, Tatsuyuki Kanamori, Kenji Tsujikawa, Tadashi Yamamuro, Hiroki Segawa, Hiroyuki Inoue
- Journal Title
  
  Analytica Chimica Acta
  
  Volume: 948 Pages: 40-47
- DOI
  10.1016/j.aca.2016.10.029
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08894
[Journal Article] Highly sensitive quantification of unconjugated 11-nor-9-carboxy-Δ9-tetrahydrocannabinol in a cannabis user’s hair using micropulverized extraction2016
- Author(s)
  Kenji Kuwayama, Hajime Miyaguchi, Tadashi Yamamuro, Kenji Tsujikawa, Tatsuyuki Kanamori, Yuko T. Iwata, Hiroyuki Inoue
- Journal Title
  
  Forensic Science International
  
  Volume: 262 Pages: e34-e36
- DOI
  10.1016/j.forsciint.2016.03.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08894
[Journal Article] Examination of rapid and simple sampling methods of blood and saliva for drug testing<br/>—To detect drugs in unchanged forms—2015
- Author(s)
  桑山健次、山室匡史、辻川健治、金森達之、岩田祐子、井上博之
- Journal Title
  
  Japanese Journal of Forensic Science and Technology
  
  Volume: 20 Issue: 1 Pages: 83-92
- DOI
  10.3408/jafst.688
- NAID
  130004942664
- ISSN
  1880-1323, 1881-4689
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24790649
[Journal Article] Comparison of sample preparation methods for zolpidem extraction from hair2015
- Author(s)
  Hajime Miyaguchi, Kenji Kuwayama
- Journal Title
  
  Forensic Toxicology
  
  Volume: 33 Issue: 1 Pages: 159-164
- DOI
  10.1007/s11419-014-0256-3
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24790649
[Journal Article] Micro-pulverized extraction pretreatment for highly sensitive analysis of 11-nor-9-carboxy-Δ9-tetrahydrocannabinol in hair by liquid chromatography/tandem mass spectrometry2015
- Author(s)
  Kenji Kuwayama, Hajime Miyaguchi, Tadashi Yamamuro, Kenji Tsujikawa, Tatsuyuki Kanamori, Yuko T. Iwata, Hiroyuki Inoue
- Journal Title
  
  Rapid Communications in Mass Spectrometry
  
  Volume: 29 Issue: 22 Pages: 2158-2166
- DOI
  10.1002/rcm.7363
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08894
[Journal Article] Time-course measurements of drugs and metabolites transferred from fingertips after drug administration: Usefulness of fingerprints for drug testing2014
- Author(s)
  Kenji Kuwayama, Tadashi Yamamuro, Kenji Tsujikawa, Hajime Miyaguchi, Tatsuyuki Kanamori, Yuko T. Iwata, Hiroyuki Inoue
- Journal Title
  
  Forensic Toxicology
  
  Volume: 32 Issue: 2 Pages: 235-242
- DOI
  10.1007/s11419-014-0228-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790649
[Journal Article] Utilization of matrix-assisted laser desorption/ionization imaging mass spectrometry to search for cannabis in herb mixtures2014
- Author(s)
  Kenji Kuwayama, Tadashi Yamamuro, Kenji Tsujikawa, Hajime Miyaguchi, Tatsuyuki Kanamori, Yuko T. Iwata, Hiroyuki Inoue
- Journal Title
  
  Analitical Bioanalytical Chemistry
  
  Volume: 406 Issue: 19 Pages: 4789-4794
- DOI
  10.1007/s00216-014-7881-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790649
[Journal Article] Time-course measurements of caffeine and its metabolites extracted from fingertips after coffee intake: a preliminary study for the detection of drugs from fingerprints2013
- Author(s)
  Kenji Kuwayama, Kenji Tsujikawa, Hajime Miyaguchi, Tatsuyuki Kanamori, Yuko T. Iwata, Hiroyuki Inoue
- Journal Title
  
  Analytical and Bioanalytical Chemistry
  
  Volume: 405 Issue: 12 Pages: 3945-3952
- DOI
  10.1007/s00216-012-6569-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790649
[Journal Article] Rapid, simple, and highly sensitive analysis of drugs in biological samples using thin-layer chromatography coupled with matrix-assisted laser desorption/ionization mass spectrometry2012
- Author(s)
  Kenji Kuwayama, Kenji Tsujikawa, Hajime Miyaguchi, Tatsuyuki Kanamori, Yuko T. Iwata, Hiroyuki Inoue
- Journal Title
  
  Analytical and Bioanalytical Chemistry
  
  Volume: 402 Issue: 3 Pages: 1257-1267
- DOI
  10.1007/s00216-011-5576-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790616
[Journal Article] Distribution measurement of amphetamine-type stimulants in organs using micropulverized extraction and liquid chromatography/tandem mass spectrometry to complement drug distribution using mass spectrometry imaging2011
- Author(s)
  Kenji Kuwayama, Kenji Tsujikawa, Hajime Miyaguchi, Tatsuyuki Kanamori, Yuko T. Iwata, Hiroyuki Inoue
- Journal Title
  
  Rapid Communications in Mass Spectrometry
  
  Volume: 25 Issue: 17 Pages: 2397-2406
- DOI
  10.1002/rcm.5145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790616
[Journal Article] Interaction of 3, 4-methylenedioxymethamphetamine and methamphetamine during metabolism by in vitro human metabolic enzymes and in rats2011
- Author(s)
  Kenji Kuwayama, Kenji Tsujikawa, Hajime Miyaguchi, Tatsuyuki Kanamori, Yuko T. Iwata, Hiroyuki Inoue
- Journal Title
  
  Journal of Forensic Sciences
  
  Volume: (In press) Issue: 4 Pages: 1008-1013
- DOI
  10.1111/j.1556-4029.2011.02039.x
- Year and Date
  2011-12-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790616
[Journal Article] Analysis of amphetamine-type stimulants and their metabolites in plasma, urine and bile by liquid chromatography with a strong cation-exchange column-tandem mass spectrometry
- Author(s)
  Kenji Kuwayama
- Journal Title
  
  Journal of Chromatography B (in press)
- NAID
  10028000428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790428
[Presentation] マイクロ分画分析を用いた毛髪内薬物分布測定における外部環境の影響2024
- Author(s)
  桑山健次，宮口一，金森達之，辻川健治，山室匡史，瀬川尋貴，岡田侑己，岩田祐子
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-19K10700
[Presentation] マイクロ分画分析による毛髪及び爪内の薬物分布測定2023
- Author(s)
  桑山健次
- Organizer
  第一回Spring-8法科学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19K10700
[Presentation] マイクロ分画分析を用いた毛髪内薬物分布測定における日常のヘアケアの影響2023
- Author(s)
  桑山健次，宮口一，金森達之，辻川健治，山室匡史，瀬川尋貴，岡田侑己，岩田祐子
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19K10700
[Presentation] Influences of temperature, humidity, light, and soil on drug stability in hair: applicability of drug-distribution measurement using micro-segmental analysis to the hair of dead bodies left in natural environments2023
- Author(s)
  Kuwayama, K., Miyaguchi, H., Kanamori, T., Tsujikawa, K., Yamamuro, T., Segawa, H., Okada, Y., Iwata, Y.T.
- Organizer
  TIAFT2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10700
[Presentation] 薬物投与経路間並びに頭毛、陰毛及び腋毛間でのマイクロ分画分析を用いた毛髪内薬物分布の違い2022
- Author(s)
  桑山健次，宮口一，金森達之，辻川健治，山室匡史，瀬川尋貴，岡田侑己，岩田祐子
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K10700
[Presentation] 水に浸された毛髪中薬物の安定性評価　-水死体の毛髪の薬物分布測定における水の影響-2022
- Author(s)
  桑山健次，宮口一，金森達之，辻川健治，山室匡史，瀬川尋貴，岡田侑己，岩田祐子
- Organizer
  日本法科学技術学会第28回学術集会
- Data Source
  KAKENHI-PROJECT-19K10700
[Presentation] 毛髪のマイクロ分画分析による連用した薬物の摂取時期推定法の開発2021
- Author(s)
  桑山健次，宮口一，金森達之，辻川健治，山室匡史，瀬川尋貴，岡田侑己，岩田祐子
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K10700
[Presentation] マイクロ分画分析を用いた毛髪及び爪内薬物分布に基づく薬物取込み経路の解析2020
- Author(s)
  桑山健次，宮口一，金森達之，辻川健治，山室匡史，瀬川尋貴，岩田祐子
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-15K08894
[Presentation] マイクロ分画分析を用いた毛髪及び爪内薬物分布に基づく薬物取込み経路の解析2020
- Author(s)
  桑山健次，宮口一，金森達之，辻川健治，山室匡史，瀬川尋貴，岩田祐子
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K10700
[Presentation] マイクロ分画分析により特定された毛髪内薬物含有領域の選択的濃縮による毛髪中の微量薬物の同定2020
- Author(s)
  桑山健次，宮口一，金森達之，辻川健治，山室匡史，瀬川尋貴，岡田侑己，岩田祐子
- Organizer
  日本法中毒学会第39年会
- Data Source
  KAKENHI-PROJECT-19K10700
[Presentation] 毛髪を用いた睡眠薬悪用犯罪の証明：高分解能質量分析による薬物スクリーニングとマイクロ分画分析による薬物摂取日の特定2019
- Author(s)
  桑山健次，宮口一，岩田祐子，金森達之，辻川健治，山室匡史，瀬川尋貴，井上博之
- Organizer
  日本法中毒学会第38年会
- Data Source
  KAKENHI-PROJECT-19K10700
[Presentation] 法科学における毛髪中薬物分析の有用性2019
- Author(s)
  桑山健次
- Organizer
  第46回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K10700
[Presentation] 毛髪及び爪を用いた薬物摂取日特定法の開発－毛髪及び爪の成長速度等のデータ収集－2019
- Author(s)
  桑山健次，宮口一，岩田祐子，金森達之，辻川健治，山室匡史，瀬川尋貴，井上博之
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-15K08894
[Presentation] 毛髪を用いた睡眠薬悪用犯罪の証明：高分解能質量分析による薬物スクリーニングとマイクロ分画分析による薬物摂取日の特定2019
- Author(s)
  桑山健次，宮口一，岩田祐子，金森達之，辻川健治，山室匡史，瀬川尋貴，井上博之
- Organizer
  日本法中毒学会第38年会
- Data Source
  KAKENHI-PROJECT-15K08894
[Presentation] 法科学における毛髪中薬物分析の有用性2019
- Author(s)
  桑山健次
- Organizer
  第46回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-15K08894
[Presentation] 単毛髪のマイクロ分画分析を利用した死亡日推定2018
- Author(s)
  桑山健次，成相舞花，宮口一，岩田祐子，金森達之，辻川健治，山室匡史，瀬川尋貴，安部寛子，岩瀬博太郎，井上博之
- Organizer
  日本法中毒学会第37年会
- Data Source
  KAKENHI-PROJECT-15K08894
[Presentation] 睡眠薬悪用犯罪の証明力強化－毛髪のマイクロ分画分析による薬物摂取日の特定－2018
- Author(s)
  桑山健次，宮口一，岩田祐子，金森達之，辻川健治，山室匡史，瀬川尋貴，井上博之
- Organizer
  日本法科学技術学会第24回学術集会
- Data Source
  KAKENHI-PROJECT-15K08894
[Presentation] 指標物質を用いた単毛髪のマイクロ分画分析による薬物摂取日推定法の実用化に向けた評価2018
- Author(s)
  桑山健次，成相舞花，宮口一，岩田祐子，金森達之，辻川健治，山室匡史，瀬川尋貴，安部寛子，岩瀬博太郎，井上博之
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K08894
[Presentation] 微小分画分析による体組織内の薬物の高解像度分布測定法の開発と応用2018
- Author(s)
  桑山健次
- Organizer
  第62回日本薬学会関東支部大会
- Invited
- Data Source
  KAKENHI-PROJECT-15K08894
[Presentation] ワンチューブマイクロ粉砕抽出法とキラル液体クロマトグラフィー/高分解能質量分析による毛髪中ゾピクロンの定量分析2017
- Author(s)
  宮口一，桑山健次
- Organizer
  日本法中毒学会第36年会
- Data Source
  KAKENHI-PROJECT-15K08894
[Presentation] 微小分画分析による毛髪及び爪内の薬物分布測定2017
- Author(s)
  桑山健次、宮口一、岩田祐子、金森達之、辻川健治、山室匡史、瀬川尋貴、井上博之
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台市
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K08894
[Presentation] 単毛髪のマイクロ分画分析による薬物摂取日の高精度推定法の開発2017
- Author(s)
  桑山健次，成相舞花，宮口一，岩田祐子，金森達之，辻川健治，山室匡史，瀬川尋貴，安部寛子，岩瀬博太郎，井上博之
- Organizer
  日本法科学技術学会第23回学術集会
- Data Source
  KAKENHI-PROJECT-15K08894
[Presentation] マイクロ分画分析による同時摂取した薬物間の毛髪内分布の違い2017
- Author(s)
  桑山健次，成相舞花，宮口一，岩田祐子，金森達之，辻川健治，山室匡史，瀬川尋貴，安部寛子，岩瀬博太郎，井上博之
- Organizer
  日本法中毒学会第36年会
- Data Source
  KAKENHI-PROJECT-15K08894
[Presentation] 毛髪中の非抱合型THC-COOH及び総THC-COOHの定量分析2016
- Author(s)
  桑山健次、阿久沢尚士、宮口　一、岩田祐子、金森達之、辻川健治、山室匡史、瀬川尋貴、井上博之
- Organizer
  日本法科学技術学会第22回学術集会
- Place of Presentation
  東京都中野区
- Year and Date
  2016-11-10
- Data Source
  KAKENHI-PROJECT-15K08894
[Presentation] Time-course measurements of drug concentrations in hair and nails after single administrations of pharmaceutical products by LC/MS/MS2016
- Author(s)
  Kenji Kuwayama, Hajime Miyaguchi, Yuko T. Iwata, Tatsuyuki Kanamori, Kenji Tsujikawa, Tadashi Yamamuro, Hiroki Segawa, Hiroyuki Inoue
- Organizer
  Asia Pacific Mass Spectrometry 2016
- Place of Presentation
  Kuala lumpur, Malaysia
- Year and Date
  2016-10-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08894
[Presentation] 単回摂取された薬物の毛髪及び爪中濃度の経時変化2016
- Author(s)
  桑山　健次、瀬川　尋貴、山室　匡史、辻川　健治、金森　達之、岩田　祐子、井上　博之
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜市
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K08894
[Presentation] Comparison of extraction methods for highly accumulated zolpidem in Japanese black hair2016
- Author(s)
  Hajime Miyaguchi, Kenji Kuwayama
- Organizer
  TIAFT meeting 2016
- Place of Presentation
  Brisbane, Australia
- Year and Date
  2016-08-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08894
[Presentation] 尿や血液の代替資料からの薬物検査　―唾液、皮膚分泌物、毛髪、爪―2015
- Author(s)
  桑山　健次、山室　匡史、辻川　健治、宮口　一、金森　達之、岩田　祐子、井上　博之
- Organizer
  日本法中毒学会第34年会
- Place of Presentation
  福岡市
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15K08894
[Presentation] 尿及び血液の代替資料からの薬物検査の有用性評価－唾液及び皮膚分泌物からの摂取薬物の検出－2015
- Author(s)
  桑山健次、山室匡史、辻川健治、金森達之、岩田祐子、井上博之
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸サンボーホール
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-24790649
[Presentation] Comparison between urine, blood, saliva, and fingerprints in forensic drug testing2015
- Author(s)
  Kenji Kuwayama, Hajime Miyaguchi, Tadashi Yamamuro, Kenji Tsujikawa, Tatsuyuki Kanamori, Yuko T. Iwata, Hiroyuki Inoue
- Organizer
  TIAFT meeting 2015
- Place of Presentation
  Florence, Italy
- Year and Date
  2015-08-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08894
[Presentation] 毛髪中ゾルピデム分析における２つの落とし穴：蓄積挙動の人種差と前処理法の抽出能力について2015
- Author(s)
  宮口　一、桑山　健次
- Organizer
  日本法中毒学会第34年会
- Place of Presentation
  福岡市
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15K08894
[Presentation] Detection of drugs in fingerprints by liquid chromatography/mass spectrometry and correlation among drug concentrations in fingerprints, urine, blood and saliva2013
- Author(s)
  Kenji Kuwayama
- Organizer
  Asia Oceania Mass Spectrometry Conference
- Place of Presentation
  Taipei, Taiwan
- Data Source
  KAKENHI-PROJECT-24790649
[Presentation] Application of drug detection from fingertips and fingerprints to investigation of drug related crimes2013
- Author(s)
  Kenji Kuwayama
- Organizer
  Mass Spectrometry 2013
- Place of Presentation
  Singapore
- Data Source
  KAKENHI-PROJECT-24790649
[Presentation] マトリックス支援レーザー脱離イオン化/イメージング質量分析による乱用薬物の臓器内分布測定の最適化2012
- Author(s)
  桑山健次
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-21790616
[Presentation] Development of automatic matrix spraying system with an air brush and a turn table for drug distribution measurement in organs by matrix-assisted laser desorption/ionization imaging mass spectrometry2012
- Author(s)
  Kenji Kuwayama
- Organizer
  PITTCON 2012
- Place of Presentation
  オーランドオレンジカウンティコンベンションセンター(アメリカ)
- Year and Date
  2012-03-13
- Data Source
  KAKENHI-PROJECT-21790616
[Presentation] 薄層クロマトグラフィー/マトリックス支援レーザー脱離イオン化/イメージング質量分析による生体試料中の薬物の同定及び画像化2011
- Author(s)
  桑山健次
- Organizer
  日本薬学会第131年会
- Place of Presentation
  ツインメッセ静岡(静岡市)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21790616
[Presentation] Development of analytical method for distribution measurement of amphetamine-type stimulants in organs2010
- Author(s)
  Kenji Kuwayama
- Organizer
  PACIFICHEM 2010
- Place of Presentation
  ハワイコンベンションセンター(アメリカ)
- Year and Date
  2010-12-15
- Data Source
  KAKENHI-PROJECT-21790616
[Presentation] Development of analytical method for distribution measurement of amphetamine-type stimulants in organs2010
- Author(s)
  桑山健次
- Organizer
  Pacifichem2010
- Place of Presentation
  ハワイコンベンションセンター(アメリカ)
- Year and Date
  2010-12-15
- Data Source
  KAKENHI-PROJECT-21790616
[Presentation] MDMA等錠剤型乱用薬物のタンパク結合及び代謝における薬物間相互作用2008
- Author(s)
  桑山健次
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-18790428
[Presentation] Effects of co-administration of 3, 4-methylenedioxymethamphetamine, methamphetamine, ketamine and caffeine on plasma concentration and on urinary and biliary excretion in rats2007
- Author(s)
  桑山健次
- Organizer
  45th International Meeting-The International Association of Forensic Toxicologists
- Place of Presentation
  シアトル
- Year and Date
  2007-08-27
- Data Source
  KAKENHI-PROJECT-18790428

1. 宮口一 (10370884)

# of Collaborated Projects: 3 results

# of Collaborated Products: 44 results

KUWAYAMA Kenji 桑山 健次

桑山 健次 クワヤマ ケンジ

Research Projects

Research Products

Co-Researchers

食品成分を指標とした毛髪のマイクロ分画分析による薬物摂取履歴・人物像解析の高度化Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Development of advanced analytical method for detection of hypnotics in urine and hairPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Determination of drug intake day by micro-segmental hair analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Detection of drugs in fingerprints using highly sensitive mass spectrometers and elucidation of relationship between drug concentrations in body fluidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

Evaluation of toxicity of drugs based on drug distributions in organs by imaging mass spectrometryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MDMA等錠剤型乱用薬物中の含有成分の相互作用による代謝及び排泄への影響Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

[Journal Article] Development of a method to evaluate the effects of external environments on drug stability in nails using micro‐segmental analysis2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of temperature, humidity, light, and soil on drug stability in hair: a preliminary study for estimating personal profiles using micro-segmental analysis of corpse hair2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of applicability of micro-segmental analysis to hair treated with heat and haircare products2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Micro-segmental hair analysis: detailed procedures and applications in forensic toxicology2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distribution profiles of diphenhydramine and lidocaine in scalp, axillary, and pubic hairs measured by micro-segmental hair analysis: good indicator for discrimination between administration and external contamination of the drugs2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Possibility of drug-distribution measurement in the hair of drowned bodies: evaluation of drug stability in water-soaked hair using micro-segmental analysis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of an improved method to estimate the days of continuous drug ingestion, based on the micro‐segmental hair analysis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 分析試料の正しい取り扱いかた 生体（毛髪）2020

Author(s)

Journal Title

NAID

KUWAYAMA Kenji 桑山健次

桑山健次クワヤマケンジ

[Journal Article] 分析試料の正しい取り扱いかた　生体（毛髪）2020

[Journal Article] Examination of rapid and simple sampling methods of blood and saliva for drug testing<br/>—To detect drugs in unchanged forms—2015