Kishi Hiroko 岸博子

… Alternative Names

KISHI Hiroko 岸博子

Less

Researcher Number	40359899
Other IDs	https://orcid.org/0000-0003-2896-7355
External Links
Affiliation (Current)	2024: 島根大学, 学術研究院医学・看護学系, 教授
Affiliation (based on the past Project Information) *help	2024: 島根大学, 学術研究院医学・看護学系, 教授 2017 – 2023: 山口大学, 大学院医学系研究科, 准教授 2011 – 2016: 山口大学, 医学(系)研究科(研究院), 准教授 2014 – 2015: 山口大学, 大学院医学系研究科, 准教授 2011 – 2012: 山口大学, 大学院・医学系研究科, 准教授 … More 2006 – 2010: 山口大学, 大学院・医学系研究科, 講師 2009: 山口大学, 大学院・医学研究科, 講師 2008: 山口大学, 大学院・医学件研究科, 講師 2007: 山口大学, 大学院・医学研究科, 講師 2006: Yamaguchi University, Molecular and Physiology and Medical Bioregulation, Associate Professor, 大学院医学系研究科, 講師 2003 – 2005: 山口大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator General physiology / Basic Section 48020:Physiology-related / Neurophysiology and muscle physiology Except Principal Investigator Food science / General physiology / Basic Section 59040:Nutrition science and health science-related / Basic Section 48020:Physiology-related / General pharmacology / Cerebral neurosurgery / Basic Section 45060:Applied anthropology-related … More / Eating habits / Neurophysiology and muscle physiology / General physiology / Cerebral neurosurgery Less
Keywords	Principal Investigator 血管平滑筋 / 異常収縮 / Rhoキナーゼ / ビメンチン / カルパイン / 血管異常収縮 / 細胞骨格 / プロテオミクス / 生理学 / 機能プロテオミクス … More / 腫瘍細胞浸潤・転移 / 病的シグナル伝達系 / 細胞運動・遊走 / 細胞骨格関連分子 / 平滑筋収縮 / 平滑筋生理 / 質量分析 / 細胞遊走 / LC-MS / MS / MALDI-TOF-MS / チロシンリン酸化 / スフィンゴ脂質 … More Except Principal Investigator 血管病 / 血管攣縮 / シグナル伝達 / 血管異常収縮 / 血管平滑筋 / 質量分析 / エクソソーム / 膜ラフト / 病態生理 / マイクロRNA / 機能的プロテオミクス / スフィンゴ脂質 / 虚血性心疾患 / paxillin / 網羅的遺伝子解析 / ヒト血管平滑筋細胞 / 血管平滑筋細胞 / アテローム性動脈硬化症 / ニコチン / プロテオーム / 食品機能 / 機能性食品 / リン酸化 / 形質転換 / 細胞遊走 / 脱分化 / カルシウム非依存性収縮 / 脳血管 / Srcファミリーチロシンキナーゼ / 脳血管攣縮 / エイコサペンタエン酸 / Rhoキナーゼ / カルシウム / 三次元セルモデル / ヒト指紋筋細胞 / 熱中症 / 暑熱馴化 / 運動トレーニング / SPC / tyrosine phosphorylation / abnormal contraction / チロシンリン酸化 / 機能性プロテオーム / 疾患エクソソーム / 分化 / 増殖 / 収縮 / 心疾患 / 血管平滑筋細胞の形質転換 / アテローム動脈硬化疾患 / paxillin ノックアウトマウス / paxillin KO mouse / 血管平滑筋収縮 / 抗酸化物質 / プロテオーム解析 / タバコ煙 / 動脈硬化性疾患 / 細胞分化・脱分化 / ヒト疾患モデル細胞 / マイクロＲＮＡ / オミックス研究 / 喫煙 / recombinant / kinase / Phosphorylation / Myosin Light chain kinase / Contraction / Actin / Myosin / Smooth Muscle / アクトミオシン / キナーゼ / 収縮制御 / 平滑筋 / プロテインキナーゼ / 大腸菌発現系 / リコンビナント / アクチン / ミオシン / MLCK / 平滑筋収縮 / Functional Proteomics / Signal Transduction / Membrane Raft / Mass Spectrometry / Vascular Smooth Muscle / 血管 / Src family tyrosine kinase / RNA interference / intracellular signal transduction / sphingolipid / Rho-kinase / calcium-independent contraction / mass spectrometry / abnormal contraction of vascular smooth muscle / Ca^<2+>非依存性収縮 / 細胞内シグナル伝達 / RNA干渉 / 細胞内カルシウム濃度 / 血管平滑筋の異常収縮 / 病的シグナル伝達 / ダイナミクス / 分子間相互作用 / 電子顕微鏡 / Fyn / コレステロール / ミクロドメイン / 活性酸素 / 酸化ストレス / 天然成分 / リポソーム / モデル膜 / 治療薬 / 脳血管障害 / 1分子 / プロテオミクス / 分化・脱分化 / マクロRNA / 細胞分化 / 血管緊張 / スフィンゴシルホスホリルコリン Less

運動による暑熱馴化の神経基盤の解明－熱中症予防に向けた基礎研究－
- Principal Investigator
  
  松崎健太郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 45060:Applied anthropology-related
- Research Institution
  Shimane University
ビメンチン断片化が起こす血管平滑筋の異常収縮機構の解明と予防治療法の研究Principal Investigator
- Principal Investigator
  
  岸博子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Shimane University
疾患エクソソームを標的とした虚血性心疾患予防のための食品機能成分の探索と先制医療
- Principal Investigator
  
  中村彰男
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Jissen Women's University
Elucidation of the mechanism by which paxillin controls vascular abnormal contraction
- Principal Investigator
  
  張影
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Yamaguchi University
Elucidation of the novel signaling pathway of vimentin-mediated abnormal vascular smooth muscle contractionPrincipal Investigator
- Principal Investigator
  
  Kishi Hiroko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Yamaguchi University
疾患エクソソームを新規バイオマーカーとして心疾患の予防・先制医療に挑む
- Principal Investigator
  
  中村彰男
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Jissen Women's University
Elucidation of the mechanism by which paxillin controls vascular abnormal contraction
- Principal Investigator
  
  Zhang Ying
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Yamaguchi University
Elucidation of the involvement of calpain and cytoskeletal proteins in the signal transduction of abnormal vascular smooth muscle contractionPrincipal Investigator
- Principal Investigator
  
  KISHI Hiroko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
New Development of Foods for Preventing Vascular Diseases-Search for Biomarkers for Disease Prevention on the plasma Exosomes-
- Principal Investigator
  
  Nakamura Akio
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Jissen Women's University
  Gunma University
The elucidation of preventive mechanism of vasospasm using food factors via membrane microdomain dynamics
- Principal Investigator
  
  KAJIYA Katsuko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Kagoshima University
Elucidation of the shared signaling pathways for intractable diseases in terms of cytoskeletal rearrangementsPrincipal Investigator
- Principal Investigator
  
  KISHI Hiroko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
Research for novel signaling molecule involving vascular smooth muscle abnormal contraction
- Principal Investigator
  
  ZHANG Ying
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
Identification of food component which selectively inhibits abnormal vascular contraction
- Principal Investigator
  
  KOBAYASHI Sei
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Food science
- Research Institution
  Yamaguchi University
Elucidation of mechanism for production of causal factor of vasospasm
- Principal Investigator
  
  KOBAYASHI Sei
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
The elucidation of the relationship between vascular smooth muscle contraction and cytoskeletal rearrangement by proteomics and functional analysisPrincipal Investigator
- Principal Investigator
  
  KISHI Hiroko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Yamaguchi University
The elucidation of molecular mechanism of vasospasm and the development of the prophylactic treatment with innovative natural ingredient.
- Principal Investigator
  
  KAJIYA Katsuko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Yamaguchi University
Clarification of molecular mechanisms of abnormal vascular contraction by functional proteomics and a single molecular analysis of signal transduction
- Principal Investigator
  
  KOBAYASHI Sei
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
脳血管攣縮の原因シグナル分子の機能解析とその選択的阻害薬の探索
- Principal Investigator
  
  小林誠
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Yamaguchi University
Mechanism of transformation of vascular smooth muscle cell-MicroRNA as regulating factor
- Principal Investigator
  
  NAKAMURA Akio
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Gunma University
機能的プロテオミクスによる脳血管攣縮の原因分子の網羅的探索と創薬への応用
- Principal Investigator
  
  小林誠
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Yamaguchi University
Functional roles of membrane domain and its localized component proteins in abnormal vascular contraction
- Principal Investigator
  
  KOBAYASHI Sei
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Yamaguchi University
New Frontier of molecular mechanism of vascular smooth muscle contraction.
- Principal Investigator
  
  NAKAMURA Akio
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Gunma University
リン酸化プロテオミクスを用いた新規血管新生因子の同定Principal Investigator
- Principal Investigator
  
  岸博子
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
脳血管の異常収縮を特異的に阻害する新規の細胞膜脂質分子の同定とシグナル伝達の解明
- Principal Investigator
  
  KOBAYASHI Sei
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Yamaguchi University
Identification of novel intracellular signaling molecules and clarification of their signal transduction mechanism which regulate abnormal vascular contraction.
- Principal Investigator
  
  KOBAYASHI Sei
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University

[Book] Chapter 13, The pivotal role of cholesterol and membrane lipid rafts in the Ca2+-sensitization of vascular smooth muscle contraction leading to vasospasm, Muscle Contraction and Cell Motility: Fundamentals and Developments, edited by Haruo Sugi2016
- Author(s)
  Ying Zhang, Hiroko Kishi, Katsuko Kajiya, Tomoka Morita, Sei Kobayashi
- Total Pages
  454
- Publisher
  Pan Stanford
- Data Source
  KAKENHI-PROJECT-16K08496
[Journal Article] High-efficient CRISPR/Cas9-mediated gene targeting to establish cell models of ciliopathies2023
- Author(s)
  Hosoba Kosuke、Morita Tomoka、Zhang Ying、Kishi Hiroko、Yamamoto Takashi、Miyamoto Tatsuo
- Journal Title
  
  Methods in Cell Biology
  
  Volume: 175 Pages: 85-95
- DOI
  10.1016/bs.mcb.2022.07.020
- ISBN
  9780443185861
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02718, KAKENHI-PROJECT-20K07261, KAKENHI-PROJECT-20K21845, KAKENHI-PROJECT-21K06782
[Journal Article] Direct active Fyn-paxillin interaction regulates vascular smooth muscle cell migration2023
- Author(s)
  Zhang Ying、Kishi Hiroko、Kobayashi Sei
- Journal Title
  
  Journal of Smooth Muscle Research
  
  Volume: 59 Issue: 0 Pages: 58-66
- DOI
  10.1540/jsmr.59.58
- ISSN
  0916-8737, 1884-8796
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06782
[Journal Article] Fyn-Mediated Paxillin Tyrosine 31 Phosphorylation Regulates Migration and Invasion of Breast Cancer Cells2023
- Author(s)
  Zhang Ying、Zheng Huanyu、Xu Ming、Maeda Noriko、Tsunedomi Ryouichi、Kishi Hiroko、Nagano Hiroaki、Kobayashi Sei
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 21 Pages: 15980-15980
- DOI
  10.3390/ijms242115980
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08850, KAKENHI-PROJECT-23K08027, KAKENHI-PROJECT-21K06782
[Journal Article] Inhibitory mechanism of tangeretin, a citrus flavone on the sphingosylphosphorylcholine (SPC)-induced vascular smooth muscle contraction.2022
- Author(s)
  Nan Li, Ying Zhang, Tomoka Morita, Hiroko Kishi, Sei Kobayashi.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 149 Issue: 4 Pages: 189-197
- DOI
  10.1016/j.jphs.2022.05.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06782, KAKENHI-PROJECT-20K07261
[Journal Article] Hesperetin Inhibits Sphingosylphosphorylcholine-Induced Vascular Smooth Muscle Contraction by Regulating the Fyn/Rho-Kinase Pathway2022
- Author(s)
  Lu Qian、Kishi Hiroko、Zhang Ying、Morita Tomoka、Kobayashi Sei
- Journal Title
  
  Journal of Cardiovascular Pharmacology
  
  Volume: 79 Issue: 4 Pages: 456-466
- DOI
  10.1097/fjc.0000000000001210
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07261, KAKENHI-PROJECT-21K06782
[Journal Article] Paxillin controls actin stress fiber formation and migration of vascular smooth muscle cells by directly binding to the active Fyn2021
- Author(s)
  Zhang Ying、Kishi Hiroko、Morita Tomoka、Kobayashi Sei
- Journal Title
  
  The FASEB Journal
  
  Volume: 35 Issue: 12
- DOI
  10.1096/fj.202101035rr
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07261, KAKENHI-PROJECT-21K06782
[Journal Article] Eicosapentaenoic acid ameliorates pulmonary hypertension via inhibition of tyrosine kinase Fyn2020
- Author(s)
  Kurahara Lin Hai、Hiraishi Keizo、Yamamura Aya、Zhang Ying、Abe Kohtaro、Yahiro Eiji、Aoki Mikiko、Koga Kaori、Yokomise Hiroyasu、Go Tetsuhiko、Ishikawa Kaori、Bo Zhang、Kishi Hiroko、Kobayashi Sei、Aoki-Shoi Narumi、Toru Satoh、Inoue Ryuji、Hirano Katsuya
- Journal Title
  
  Journal of Molecular and Cellular Cardiology
  
  Volume: 148 Pages: 50-62
- DOI
  10.1016/j.yjmcc.2020.08.013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07309, KAKENHI-PROJECT-20K07061, KAKENHI-PROJECT-20K07092, KAKENHI-PROJECT-20K07261, KAKENHI-PROJECT-20K07269, KAKENHI-PROJECT-17KK0179, KAKENHI-PROJECT-18K06875
[Journal Article] Add-on therapy with traditional Chinese medicine: An efficacious approach for lipid metabolism disorders2018
- Author(s)
  Ying Zhang, Hiroko Kishi, Sei Kobayashi
- Journal Title
  
  Pharmacological Research
  
  Volume: 134 Pages: 200-211
- DOI
  10.1016/j.phrs.2018.06.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06875, KAKENHI-PROJECT-16K08496
[Journal Article] The nutritional characteristics of the hypotensive WASHOKU-modified DASH diet: a sub-analysis of the DASH-JUMP study2018
- Author(s)
  Atsuko Kawamura, Katsuko Kajiya, Hiroko Kishi, Junko Inagaki,　Makoto Mitarai, Hiroshi Oda, Seiji Umemoto, Sei Kobayashi
- Journal Title
  
  Current Hypertension Reviews
  
  Volume: 14 Issue: 1 Pages: 1-10
- DOI
  10.2174/1573402114666180405100430
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07795, KAKENHI-PROJECT-15K09123, KAKENHI-PROJECT-16K08496
[Journal Article] Omega-3 and omega-6 DPA equally inhibit the sphingosylphosphorylcholine-induced Ca2+-sensitization of vascular smooth muscle contraction via inhibiting Rho-kinase activation and translocation.2017
- Author(s)
  Ying Zhang, Min Zhang, Bochao Lyu, Hiroko Kishi and Sei Kobayashi
- Journal Title
  
  Scientific Report
  
  Volume: 7 Issue: 1 Pages: 1-14
- DOI
  10.1038/srep36368
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08496, KAKENHI-PROJECT-15K18970
[Journal Article] Effects of the DASH-JUMP dietary intervention in Japanese participants with high-normal blood pressure and stage 1 hypertension: an open-label single-arm trial.2016
- Author(s)
  Kawamura A, Kajiya K, Kishi H, Inagaki J, Mitarai M, Oda H, Umemoto S, Kobayashi S.
- Journal Title
  
  Hypertens Res
  
  Volume: 39 Issue: 11 Pages: 777-785
- DOI
  10.1038/hr.2016.76
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09123, KAKENHI-PROJECT-16K08496
[Journal Article] Effects of the DASH-JUMP dietary intervention in Japanese participants with high-normal blood pressure and stage I hypertension: an open-label single-arm trial2016
- Author(s)
  Atsuko Kawamura, Katsuko Kajiya, Hiroko Kishi, Junko INagaki, Makoto Mitarai, Hiroshi Oda, Seiji Umemoto, Sei Kobayashi
- Journal Title
  
  Hypertension Research
  
  Volume: 0 Pages: 0-0
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25450171
[Journal Article] Fatty acid-binding protein 7 regulates function of caveolae in astrocytes through expression of caveolin-12015
- Author(s)
  Yoshiteru Kagawa, Yuki Yasumoto, Kazem Sharifi, Majid Ebrahimi, Ariful Islam, Hirofumi Miyazaki, Yui Yamamoto, Tomoo Sawada, Hiroko Kishi, Sei Kobayashi, Motoko Maekawa, Takeo Yoshikawa, Eiichi Takaki Akira Nakai, Hiroshi Kogo, Toyoshi Fujimoto, Yuji Owada
- Journal Title
  
  Glia
  
  Volume: 63 Pages: 780-794
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659113
[Journal Article] Fatty acid-binding protein 7 regulates function of caveolae in astrocytes through expression of caveolin-12015
- Author(s)
  Yoshiteru Kagawa, Yuki Yasumoto, Kazem Sharifi, Majid Ebrahimi, Ariful Islam, Hirofumi Miyazaki, Yui Yamamoto, Tomoo Sawada, Hiroko Kishi, Sei Kobayashi, Motoko Maekawa, Takeo Yoshikawa, Eiichi Takaki, Akira Nakai, Hiroshi Kogo, Toyoshi Fujimoto, Yuji Owada
- Journal Title
  
  Glia
  
  Volume: 63 Pages: 780-794
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460290
[Journal Article] Fatty acid-binding protein 7 regulates function of caveolae in astrocytes through expression of caveolin-12015
- Author(s)
  Yoshiteru Kagawa, Yuki Yasumoto, Kazem Sharifi, Majid Ebrahimi, Ariful Islam, Hirofumi Miyazaki, Yui Yamamoto, Tomoo Sawada, Hiroko Kishi, Sei Kobayashi, Motoko Maekawa, Takeo Yoshikawa, Eiichi Takaki Akira Nakai, Hiroshi Kogo, Toyoshi Fujimoto, Yuji Owada
- Journal Title
  
  Glia
  
  Volume: 63 Pages: 780-794
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380077
[Journal Article] 質量分析計による蛋白質同定～シグナル伝達研究への応用～2015
- Author(s)
  岸博子、張影、小林誠
- Journal Title
  
  山口医学
  
  Volume: 64 Pages: 77-181
- NAID
  130005239550
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460290
[Journal Article] Interaction of peptide-bound beads with lipopolysaccharide and lipoproteins.2014
- Author(s)
  Suzuki,M.M.,Matsumoto,M.,Omi,H.,Kobayashi,T.,Nakamura, A.,Kishi,H.,Kobayashi, S., and Takagi, T.
- Journal Title
  
  J Microbiol Methods.
  
  Volume: 100 Pages: 137-141
- DOI
  10.1016/j.mimet.2014.02.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590295, KAKENHI-PROJECT-25460290
[Journal Article] Phosphorylation of the Kinase Domain Regulates Autophosphorylation of Myosin IIIA and Its Translocation in Microvilli2014
- Author(s)
  Byung Chull An, Tsuyoshi Sakai, Shigeru Komaba, Hiroko Kishi, Sei Kobayashi, Jin Young Kim, Reiko Ikebe, Mistuo Ikebe
- Journal Title
  
  Biochemistry
  
  Volume: 53 Issue: 49 Pages: 7835-7845
- DOI
  10.1021/bi501247z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380077, KAKENHI-PROJECT-23659113, KAKENHI-PROJECT-25460290
[Journal Article] The interaction of Fyn and a cytoskeleton-related protein which is identified as a novel signaling molecule in SPC/Fyn/ROK pathway to mediate abnormal VSM contraction2013
- Author(s)
  Hiroko Kishi, Ying Zhang, Katsuko Kajiya, Tomohiko Kimura, Kenji Miyanari, Sei Kobayashi
- Journal Title
  
  Experimental & Clinical Cardiology
  
  Volume: 18 Pages: 173-174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25450171
[Journal Article] Structural and functional analysis of membrane microdomain as a platform for cell signaling pathway of Ca2+-sensitization of vascular smooth muscle contraction2013
- Author(s)
  Katsuko Kajiya, Kazutaka Nojimoto, Hiroko Kishi, Yuichi Takada, Ying Zhang, Sei Kobayashi
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 63 Pages: 116-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25450171
[Journal Article] New avenues to vascular disease prevention by food components2012
- Author(s)
  Katsuko Kajiya, Hiroko Kishi, Yuichi Takada, Ying Zhang, Tomohiko Kimura, Kenji Miyanari, Hiroshi Hagihara, Sei Kobayashi
- Journal Title
  
  Foods & Food Ingredients Journal of Japan
  
  Volume: 217(3) Pages: 284-289
- NAID
  40019419438
- URL
  http://www.ffcr.or.jp/zaidan/FFCRHOME.nsf/pages/ffij-e217(3)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500364
[Journal Article] New avenues to vascular disease prevention by food components, Foods2012
- Author(s)
  Katsuko Kajiya, Hiroko Kishi, Yuichi Takada, Ying Zhang, Tomohiko Kimura, Kenji Miyanari, Hiroshi Hagihara, Sei Kobayashi
- Journal Title
  
  Food Ingredients Journal of Japan
  
  Volume: 217 Pages: 284-289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580131
[Journal Article] Sphingosylphosphorylcholine induces stress fiber formation via activation of Fyn-RhoA-ROCK signaling pathway in fibroblasts2012
- Author(s)
  Dan xu
- Journal Title
  
  Cellular Signaling
  
  Volume: 24 Issue: 1 Pages: 282-289
- DOI
  10.1016/j.cellsig.2011.09.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J04493, KAKENHI-PROJECT-22500364, KAKENHI-PROJECT-22580131, KAKENHI-PROJECT-23380077, KAKENHI-PROJECT-23659113
[Journal Article] 食品成分による血管病予防の新展開2012
- Author(s)
  加治屋勝子、岸博子、高田雄一、張影、木村友彦、宮成健司、萩原弘、小林誠
- Journal Title
  
  FFIジャーナル
  
  Volume: 217 Pages: 284-289
- NAID
  40019419438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380077
[Journal Article] 食品成分による血管病予防の新展開2012
- Author(s)
  加治屋勝子、岸博子、高田雄一、張影、木村友彦、宮成健司、萩原弘、小林誠
- Journal Title
  
  FFIジャーナル
  
  Volume: 217 Pages: 284-289
- NAID
  40019419438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659113
[Journal Article] Synchronous phosphorylation of CPI-17 and MYPT1 is essential for inducing Ca(2+) sensitization in intestinal smooth muscle2011
- Author(s)
  Mori D, Hori M, Murata T, Ohama T, Kishi H, Kobayashi S, Ozaki H
- Journal Title
  
  Neurogastroenterol Motil
  
  Volume: 23(12) Issue: 12 Pages: 1111-1122
- DOI
  10.1111/j.1365-2982.2011.01799.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20228005, KAKENHI-PROJECT-21380178, KAKENHI-PROJECT-22500364, KAKENHI-PROJECT-22658089
[Journal Article] Focused proteomic approach to identify novel signaling molecules for abnormal vascular smooth muscle contraction.2010
- Author(s)
  岸博子, et al.
- Journal Title
  
  J Physiol Sci 60 (Supp)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390059
[Journal Article] Focused proteomic approach to identify novel signaling molecules for abnormal vascular smooth muscle contraction2010
- Author(s)
  Hiroko Kishi, Shoko Nakajima, Hozumi Kawamichi, Katsuko Kajiya, Yuichi Takada, Daisuke Tokumori, Sei Kobayashi
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 60(Supplement 1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500364
[Journal Article] Focused proteomicsによる、血管平滑筋異常収縮の新規病的シグナル分子の探索2010
- Author(s)
  岸博子, ら
- Journal Title
  
  日本平滑筋学会雑誌 14巻
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390059
[Journal Article] Focused Proteomicsによる、血管平滑筋異常収縮の新規病的シグナル分子の探索2010
- Author(s)
  岸博子、中島彰子、川道穂津美、加治屋勝子、王晨、高田雄一、小林誠
- Journal Title
  
  日本平滑筋学会雑誌
  
  Volume: 14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500364
[Journal Article] Focused proteomic approach to identify novel signaling molecules for abnormal vascular smooth muscle contraction2010
- Author(s)
  Hiroko Kishi, et al.
- Journal Title
  
  The Journa of Physiological Sciences
  
  Volume: 60(Supplement 1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390059
[Journal Article] Focused Proteomicsによる、血管平滑筋異常収縮の新規病的シグナル分子の探索2010
- Author(s)
  岸博子, ら
- Journal Title
  
  日本平滑筋学会雑誌
  
  Volume: 14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390059
[Journal Article] Nifedipine activates PPARand exerts an antioxidative action through Cu/ZnSOD independent of blood-pressure lowering in SHRSP2010
- Author(s)
  Ryo Hashimoto, Seiji Umemoto、Fengling Guo, Kyoko Umeji, Shinichi Itoh, Hiroko Kishi, Sei Kobayashi, and Masunori Matsuzaki
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 17(8) Pages: 785-795
- URL
  https://www.jstage.jst.go.jp/browse/jat/17/8/_contents
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500364
[Journal Article] Elevated concentrations of sphingosylphosphorylcholine in cerebrospinal fluid after subarachnoid hemorrhage : A possible role as a spasmogen.2009
- Author(s)
  T.Kurokawa, Y.Yumiya, H.Fujisawa, S.Shirao, S.Kashiwagi, M.Sato, H.Kishi, S.Miwa, K.Mogami, S.Kato, T.Akimura, M.Soma, K.Ogasawara, A.Ogawa, S.Kobayashi, M.Suzuki
- Journal Title
  
  J Clin Nuerosci 16
  
  Pages: 1064-1068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390059
[Journal Article] Role of non-kinase activity of myosin light-chain kinase in regulating smooth muscle contraction, a review dedicated to Dr. Setsuro Ebashi.2008
- Author(s)
  Nakamura A, Xie C, Zhang Y, Gao Y, Wang HH, Ye LH, Kishi H, Okagaki T, Yoshiyama S, Hayakawa K, Ishikawa R, Kohama K.
- Journal Title
  
  Biochem Biophys Res Commun. 369
  
  Pages: 135-143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590240
[Journal Article] Role of non-kinase activity of myosin light- chain kinase in regulating smooth muscle contraction, a review dedicated to Dr. Setsuro Ebashi2008
- Author(s)
  Nakamura, A., Xie, C., Zhang, Y., Gao, Y., Wang, H-H., Ye, L-H., Kishi, H., Okagaki, T., Yoshiyama, S., Hayakawa, K., Ishikawa, R., Kohama, K.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 369
  
  Pages: 135-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590240
[Journal Article] 血管平滑筋Ca^<2+>感受性増強の細胞内シグナル伝達におけるFynチロシンキナーゼおよび細胞膜ラフトの重要性2007
- Author(s)
  岸博子, ら
- Journal Title
  
  日薬理雑誌 129
  
  Pages: 245-251
- NAID
  10019563243
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17300128
[Journal Article] Involvement of Fyn tyrosine kinase in actin stress fiber formation in fibroblasts2007
- Author(s)
  Xu, D., Kishi, H., Kawamichi, H., Kajiya, K., Takada, Y., Kobayashi, S
- Journal Title
  
  FEBS Lett 581(peer-reviewed)
  
  Pages: 5227-5233
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300128
[Journal Article] The Role of Protein Tyrosine Kinase Fyn in Ca^<2+> Sensitization of Vascular Smooth Muscle Contraction.2006
- Author(s)
  Hiroko Kishi
- Journal Title
  
  Circulation Journal 70 (suppl)
  
  Pages: 197-197
- Data Source
  KAKENHI-PROJECT-17300128
[Journal Article] The involvement of Fyn tyrosine kinase and membrane rafts in the signal transduction of abnormal vascular smooth muscle contraction.2006
- Author(s)
  Hiroko Kishi
- Journal Title
  
  The Journal of Physiological Sciences 56(suppl)
- NAID
  130005448081
- Data Source
  KAKENHI-PROJECT-17659447
[Journal Article] The inhibitory Mechanism of Eicosapentaenoic Acid on the Ca^<2+> Sensitization Mediated of SPC/Fyn/Rho-kinase pathway, in which Membrane Rafts Are Involved.2006
- Author(s)
  Hiroko Kishi
- Journal Title
  
  Circulation Journal 70 (suppl)
  
  Pages: 413-413
- Data Source
  KAKENHI-PROJECT-17300128
[Journal Article] The Role of Protein Tyrosine Kinase Fyn in Ca^<2+> Sensitization of Vascular Smooth Muscle Contraction.2006
- Author(s)
  Hiroko Kishi
- Journal Title
  
  Circulation Journal 70(suppl)
  
  Pages: 197-197
- Data Source
  KAKENHI-PROJECT-17659447
[Journal Article] The inhibitory Mechanism of Eicosapentaenoic Acid on the Ca^<2+> Sensitization Mediated of SPC/Fyn/Rho-kinase pathway, in which Membrane Rafts Are Involved.2006
- Author(s)
  Hiroko Kishi
- Journal Title
  
  Circulation Journal 70(suppl)
  
  Pages: 413-413
- Data Source
  KAKENHI-PROJECT-17659447
[Journal Article] The involvement of Fyn tyrosine kinase and membrane rafts in the signal transduction of abnormal vascular smooth muscle contraction.2006
- Author(s)
  Hiroko Kishi
- Journal Title
  
  The Journal of Physiological Sciences 56 (suppl)
- NAID
  130005448081
- Data Source
  KAKENHI-PROJECT-17300128
[Journal Article] Cholesterol primes vascular smooth muscle to induce Ca^<2+> sensitization mediated by a sphingosylphosphorylcholine-Rho-kinase pathway : possible role for membrane raft2006
- Author(s)
  Morikage, N., Kishi, H., Sato, M., Guo, F., Shirao, S., Yano, T., Soma, M., Hamano, K., Esato, K., Kobayashi, S
- Journal Title
  
  Circ Res 99(peer-reviewed)
  
  Pages: 299-306
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300128
[Journal Article] The inhibitory effects of eicosapentaenoic acid on the Ca^<2+> sensitization mediated by SPC/Fyn/Rho-kinase pathway, in which membrane lipid rafts is involved.2005
- Author(s)
  Hiroko Kishi
- Journal Title
  
  Experimental and Clinical Cardiology 10(2)
  
  Pages: 123-123
- Data Source
  KAKENHI-PROJECT-17300128
[Journal Article] Cholesterol primes vascular smooth muscle to induce Ca^<2+> sensitization mediated by a sphingosylphosphorylcholine/Src family tyrosine kinase-Rho-kinase pathway : possible involvement of membrane lipid rafts.2005
- Author(s)
  Hiroko Kishi
- Journal Title
  
  The Japanese Journal of Physiology 55 (suppl)
- NAID
  130007039321
- Data Source
  KAKENHI-PROJECT-17300128
[Journal Article] Sphingomyelinase causes endothelium-dependent vasorelaxation through endothelial nitric oxide production without cytosolic Ca^<1+> elevation2005
- Author(s)
  Mogami, K., Kishi, H., Kobayashi, S
- Journal Title
  
  FEBS Lett 579(peer-reviewed)
  
  Pages: 393-397
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300128
[Journal Article] Cholesterol primes vascular smooth muscle to induce Ca^<2+> sensitization mediated by a sphingosylphosphorylcholine/Src family tyrosine kinase-Rho-kinase pathway : possible involvement of membrane lipid rafts.2005
- Author(s)
  Hiroko Kishi
- Journal Title
  
  The Japanese Journal of Physiology 55(suppl)
- NAID
  130007039321
- Data Source
  KAKENHI-PROJECT-17659447
[Journal Article] The inhibitory effects of eicosapentaenoic acid on the Ca^<2+> sensitization mediated by SPC/Fyn/Rho-kinase pathway, in which membrane lipid rafts is involved.2005
- Author(s)
  Hiroko Kishi
- Journal Title
  
  Experimental and Clinical Cardiology 10(2)
  
  Pages: 123-123
- Data Source
  KAKENHI-PROJECT-17659447
[Journal Article] A proteomic approach to identify novel signaling molecules mediating Ca^<2+> sensitization of vascular smooth muscle contraction2004
- Author(s)
  Hiroko Kishi
- Journal Title
  
  Circulation Journal 68(Suppl.I)
  
  Pages: 419-419
- Data Source
  KAKENHI-PROJECT-15790118
[Journal Article] A proteomic approach to identify the downstream signaling molecules of Src family tyrosine kinase which mediates Cat^<2+>-sensitization of vascular smooth muscle contraction2004
- Author(s)
  Hiroko Kishi
- Journal Title
  
  The Japanese Journal of Physiology 54
- Data Source
  KAKENHI-PROJECT-15790118
[Journal Article] エイコサペンタエン酸(EPA)による血管攣縮の予防効果2003
- Author(s)
  岸博子
- Journal Title
  
  月刊バイオインダストリー 20
  
  Pages: 5-13
- Data Source
  KAKENHI-PROJECT-15790118
[Journal Article] Sphingosylphosphorylcholine (SPC) and Src family tyrosine kinase are novel upstream messengers for Rho-kinase-mediated Ca^<2+> sensitization2003
- Author(s)
  Hiroko Kishi
- Journal Title
  
  The Japanese Journal of Physiology 53
- Data Source
  KAKENHI-PROJECT-15790118
[Journal Article] スフィンゴシルポスホリルコリン(SPC)によるカルシウム感受性増強のシグナル伝達におけるSrc familyチロシンキナーゼの下流分子の検索2003
- Author(s)
  岸博子
- Journal Title
  
  Journal of Smooth Muscle Research 7・1
- Data Source
  KAKENHI-PROJECT-15790118
[Patent] 安息香酸誘導体を含む血管攣縮抑制剤、食品及び食品添加剤2017
- Inventor(s)
  小林　誠、岸　博子、高松日出子、石川敦子
- Industrial Property Rights Holder
  山口大学、株式会社タカマ
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-237056
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16K08496
[Patent] SPC/Fyn/Rhoキナーゼシグナル伝達経路の阻害剤2015
- Inventor(s)
  岸博子、張影、小林誠
- Industrial Property Rights Holder
  山口大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015-05-07
- Data Source
  KAKENHI-PROJECT-25460290
[Patent] 血管攣縮抑制剤2014
- Inventor(s)
  高松日出子、小林誠、宮成健司、岸　博子、他3名
- Industrial Property Rights Holder
  株式会社タカマ
- Industrial Property Rights Type
  特許
- Filing Date
  2014-09-10
- Data Source
  KAKENHI-PROJECT-25460290
[Patent] 血管攣縮抑制剤2014
- Inventor(s)
  小林　誠、高柿了大、岸　博子、張影、加治屋勝子、渡邉和晃
- Industrial Property Rights Holder
  国立大学法人山口大学、株式会社ラフィーネインターナショナル
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-14
- Data Source
  KAKENHI-PROJECT-23380077
[Patent] 血管攣縮抑制剤2014
- Inventor(s)
  高松日出子、小林誠、宮成健司、岸　博子、他3名
- Industrial Property Rights Holder
  株式会社タカマ
- Industrial Property Rights Type
  特許
- Filing Date
  2014-09-10
- Data Source
  KAKENHI-PROJECT-23659113
[Patent] 血管攣縮抑制剤2014
- Inventor(s)
  小林誠、高柿了大、岸博子、張影、加治屋勝子、渡邉和晃
- Industrial Property Rights Holder
  山口大学、株式会社ラフィ‐ネインタ‐ナショナル
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-210258
- Filing Date
  2014-10-14
- Data Source
  KAKENHI-PROJECT-25893150
[Patent] 血管攣縮抑制剤2014
- Inventor(s)
  小林　誠、高柿了大、岸　博子、張　影、加治屋勝子、渡邉和晃
- Industrial Property Rights Holder
  国立大学法人山口大学、株式会社ラフィーネインターナショナル
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-14
- Data Source
  KAKENHI-PROJECT-25460290
[Patent] 血管攣縮抑制剤2014
- Inventor(s)
  高松日出子、小林誠、宮成健司、岸　博子、他3名
- Industrial Property Rights Holder
  株式会社タカマ
- Industrial Property Rights Type
  特許
- Filing Date
  2014-09-10
- Data Source
  KAKENHI-PROJECT-23380077
[Patent] 血管攣縮抑制剤2014
- Inventor(s)
  小林　誠、高柿了大、岸　博子、張影、加治屋勝子、渡邉和晃
- Industrial Property Rights Holder
  国立大学法人山口大学、株式会社ラフィーネインターナショナル
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-14
- Data Source
  KAKENHI-PROJECT-23659113
[Patent] 血管弛緩作用を有するペプチド及び血管弛緩剤2013
- Inventor(s)
  小林誠、木村友彦、岸博子、加治屋勝子、高田雄一、白土絵理
- Industrial Property Rights Holder
  小林誠、木村友彦、岸博子、加治屋勝子、高田雄一、白土絵理
- Industrial Property Rights Type
  特許
- Filing Date
  2013-09-09
- Data Source
  KAKENHI-PROJECT-25450171
[Patent] 血管弛緩作用を有するペプチド及び血管弛緩剤2013
- Inventor(s)
  小林誠、木村友彦、岸博子、加治屋勝子、高田雄一、白土絵里
- Industrial Property Rights Holder
  山口大学、林兼産業株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2013-09-09
- Data Source
  KAKENHI-PROJECT-23659113
[Patent] 血管弛緩作用を有するペプチドおよび血管弛緩剤2013
- Inventor(s)
  小林　誠、木村友彦、岸　博子、加治屋勝子、高田雄一、白土絵里
- Industrial Property Rights Holder
  国立大学法人山口大学、林兼産業株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2013-09-09
- Data Source
  KAKENHI-PROJECT-25460290
[Patent] 血管病予防に効果を有する食品組成物2013
- Inventor(s)
  小林誠、岸博子
- Industrial Property Rights Holder
  国立大学法人山口大学
- Acquisition Date
  2013-02-01
- Data Source
  KAKENHI-PROJECT-22500364
[Patent] 平滑筋収縮抑制剤2012
- Inventor(s)
  小林誠、岸博子、横地俊弘、中原東郎
- Industrial Property Rights Holder
  国立大学法人山口大学
- Acquisition Date
  2012-11-09
- Data Source
  KAKENHI-PROJECT-22500364
[Patent] 血管異常収縮の抑制剤2012
- Inventor(s)
  小林誠、岸博子、中島幹夫、前田祥範
- Industrial Property Rights Holder
  国立大学法人山口大学、国立大学法人佐賀大学
- Acquisition Date
  2012-10-12
- Data Source
  KAKENHI-PROJECT-22500364
[Patent] 平滑筋収縮抑制剤2012
- Inventor(s)
  扇谷悟、森田直樹、花田啓子、小林利克、小林誠、岸博子、宮下和夫、細川雅史
- Industrial Property Rights Holder
  国立大学法人山口大学
- Acquisition Date
  2012-12-21
- Data Source
  KAKENHI-PROJECT-22500364
[Presentation] The role of vimentin cleavage in the signal transduction of abnormal vascular smooth muscle contraction2023
- Author(s)
  Hiroko Kishi, Keisuke Shigenobu, Tatsuo Miyamoto
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] 血管平滑筋異常収縮のシグナル伝達におけるカルパイン活性化および中間径フィラメントビメンチン断片化の役割の解明2022
- Author(s)
  岸博子、路倩、森田知佳、張影、李楠、小林誠
- Organizer
  第64回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] 血管平滑筋異常収縮のシグナル伝達におけるカルパイン活性化およびビメンチン断片化の役割の解明2022
- Author(s)
  岸博子、森田知佳、張影、李楠、宮本達雄
- Organizer
  第74回日本生理学会中国四国地方会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] 血管平滑筋異常収縮のシグナル伝達における中間径フィラメントビメンチン断片化の役割の解明2022
- Author(s)
  岸博子、路倩、森田知佳、張影、李楠、小林誠
- Organizer
  第６４回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-21K06782
[Presentation] Paxillinは活性型Fynに直接結合することにより血管平滑筋細胞のストレスファイバー形成と細胞遊走を制御する2022
- Author(s)
  張影、森田知佳、小林誠、岸博子、宮本達雄
- Organizer
  第６４回日本平滑筋学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06782
[Presentation] The role of vimentin cleavage and calpain in the Ca2+-sensitization of vascular smooth muscle contraction2022
- Author(s)
  Hiroko Kishi, Qian Lu, Tomoka Morita, Ying Zhang, Nan Li, Sei Kobayashi
- Organizer
  第99回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Paxillin は活性型Fyn に直接結合することにより血管平滑筋細胞のストレスファイバー形成と細胞遊走を制御する2022
- Author(s)
  張影、森田知佳、小林誠、岸博子、宮本達雄
- Organizer
  第64回日本平滑筋学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] 血管平滑筋異常収縮の分子機構におけるカルパイン活性化およびビメンチン断片化の役割2022
- Author(s)
  岸博子
- Organizer
  筋生理の集い
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Madagascine induces vasodilatation via AMPK-mediated eNOS activation and ROCK inhibition2021
- Author(s)
  Bochao Lyu, Dapeng Chen, Yuan Lin, Ying Zhang, Tomoka Morita, Hiroko Kishi, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] 血管平滑筋異常収縮のシグナル伝達におけるカルパインの役割の解明2021
- Author(s)
  岸博子、路倩、森田知佳、張影、呂博超、李楠、小林誠
- Organizer
  第63回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Madagascine induces vasodilatation via AMPK-mediated eNOS activation and ROCK inhibition2021
- Author(s)
  Bochao Lyu, Dapeng Chen, Yuan Lin, Ying Zhang, Tomoka Morita, Hiroko Kishi, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Paxillin is a novel signaling molecule which regulates abnormal vascular contraction mediated by an SPC/Fyn/Rho-kinase pathway2021
- Author(s)
  Ying Zhang, Tomoka Morita, Bochao Lyu, Dan Cui, Hiroko Kishi, Min Zhang, Qian Lu, Nan Li, Eiji Ikeda, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Fyn KOマウスの脳底動脈と前腸間膜動脈のスフィンゴシルホスホリルコリンに対する反応性について2021
- Author(s)
  森田知佳、張影、岸博子、小林誠
- Organizer
  第６3回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-21K06782
[Presentation] Compound B from traditional Chinese medicine inhibits the Rho-kinase (ROK)-mediated Ca2+-sensitization of vascular smooth muscle contraction induced by a spasmogen, sphingosylphosphorylcholine (SPC)2021
- Author(s)
  Minhui Xu, Min Zhang, Bochao Lyu, Qian Lu, Nan Li, Ying Zhang, Tomoka Morita, Hiroko Kishi, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Sphingosylphosphorylcholine induced contraction in basilar arteries of Fyn knockout mice2021
- Author(s)
  Tomoka Morita, Ying Zhang, Hiroko Kishi, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 異常収縮刺激時Fynの活性化によるpaxillinのチロシンリン酸化について2021
- Author(s)
  張　影、呂　博超、森田　知佳、岸　博子、路　倩、李　楠、小林　誠
- Organizer
  第６3回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-21K06782
[Presentation] 血管平滑筋異常収縮のシグナル伝達におけるカルパインの役割の解明2021
- Author(s)
  岸博子、路倩、森田知佳、張影、呂博超、李楠、小林誠
- Organizer
  第６3回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-21K06782
[Presentation] The role of calpain activation and vimentin cleavage in Ca2+-sensitization of vascular smooth muscle contraction2021
- Author(s)
  Hiroko Kishi, Qian Lu, Tomoka Morita, Ying Zhang, Bochao Lyu, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Molecular mechanism of component T inhibiting abnormal vascular contraction and migration of MDA-MB-231 cancer cells2021
- Author(s)
  Nan Li, Min Zhang, Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] The role of calpain activation and vimentin cleavage in Ca2+-sensitization of vascular smooth muscle contraction2021
- Author(s)
  Hiroko Kishi, Qian Lu, Tomoka Morita, Ying Zhang, Bochao Lyu, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Compound B from traditional Chinese medicine inhibits the Rho-kinase (ROK)-mediated Ca2+-sensitization of vascular smooth muscle contraction induced by a spasmogen, sphingosylphosphorylcholine (SPC)2021
- Author(s)
  Minhui Xu, Min Zhang, Bochao Lyu, Qian lu, Nan li, Ying Zhang, Tomoka Morita, Hiroko Kishi, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] The inhibitory effect and mechanism exploration of compound H on sphingosylphosphorylcholine (SPC)-induced contraction in vascular smooth muscle2021
- Author(s)
  Qian Lu, Bochao Lyu, Ying Zhang, Tomoka Morita, Hiroko Kishi, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] The inhibitory effect and mechanism exploration of compound H on sphingosylphosphorylcholine (SPC)-induced contraction in vascular smooth muscle2021
- Author(s)
  Qian Lu, Bochao Lyu, Ying Zhang, Tomoka Morita, Hiroko Kishi, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Molecular mechanism of component T inhibiting abnormal vascular contraction and migration of MDA-MB-231 cancer cells2021
- Author(s)
  Nan Li, Min Zhang, Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Deletion of Paxillin Attenuates Sphingosylphosphorylcholine (SPC)-Induced Abnormal Contraction of Vascular Smooth Muscle by Inhibiting Rho-kinase Activity2021
- Author(s)
  Ying Zhang, Tomoka Morita, Bochao Lyu, Dan Cui, Hiroko Kishi, Min Zhang, Qian Lu, Nan Li, Eiji Ikeda, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Sphingosylphosphorylcholine induced contraction in basilar arteries of Fyn knockout mice.2021
- Author(s)
  Tomoka Morita, Ying Zhang, Hiroko Kishi, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Specific inhibitory effects of compound T, upon pre- or post-treated, on the sphingosylphosphorylcholine (SPC)-induced Ca2+-sensitization of vascular smooth muscle contraction through suppressing the Fyn/Rho-kinase signaling pathway, without affecting Ca2+-dependent contraction2021
- Author(s)
  Nan Li, Ying Zhang, Hiroko Kishi, Tomoka Morita, Bochao Lyu, Sei Kobayashi.
- Organizer
  第６3回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-21K06782
[Presentation] SPC/Fyn/ROK系による血管平滑筋収縮のCa2+-sensitizationにおけるカルパインの活性化とビメンチン断片化の役割の解明2020
- Author(s)
  岸博子、路倩、森田知佳、張影、呂博超、張敏、李楠、徐敏慧、小林誠
- Organizer
  第62回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Madagascine induces vasodilatation via activation of AMPK2020
- Author(s)
  Bochao Lyu, Dapeng Chen, Yuan Lin, Ying Zhang, Tomoka Morita, Hiroko Kishi, Sei Kobayashi
- Organizer
  第62回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] SPC/Fyn/ROK系による血管平滑筋収縮のCa2+-sensitizationにおけるカルパインの活性化とビメンチン断片化の役割の解明2020
- Author(s)
  岸博子、路倩、森田知佳、張影、呂博超、張敏、李楠、徐敏慧、小林誠
- Organizer
  第６２回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] The inhibitory mechanism of T on MDA-MB-231 breast cancer cell migration and the mechanism of inhibiting the SPC-induced abnormal contraction.2020
- Author(s)
  Nan Li, Min Zhang, Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  第62回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Novel signaling molecules which can regulate both Ca2+-sensitization of vascular contraction and cancer cell migration2020
- Author(s)
  Sei Kobayashi, Bochao Lyu, Min Zhang, Ying Zhang, Hiroko Kishi, Tomoka Morita
- Organizer
  第97回日本生理学会　3月17日～19日　誌上開催
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Madagascine induces vasodilatation via activation of AMPK2020
- Author(s)
  Bochao Lyu, Dapeng Chen, Yuan Lin, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  第６２回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Compound H inhibits sphingosylphosphorylcholine（SPC）-induced contraction via suppressing Fyn/Rho-kinase pathway in vascular smooth muscle2020
- Author(s)
  Qian Lu, Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第６２回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Compound H inhibits sphingosylphosphorylcholine-induced contraction via suppressing Fyn/Rho-kinase pathway in vascular smooth muscle2020
- Author(s)
  Qian Lu, Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第62回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] スフィンゴシルホスホリルコリン（SPC）による血管平滑筋のCa2+感受性収縮におけるパキシリンの役割2020
- Author(s)
  張影、呂博超、森田知佳、崔丹、岸博子、張敏、路倩、李楠、池田栄二、小林誠
- Organizer
  第62回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] The role of calpain activation and vimentin cleavage in the signal transduction of abnormal vascular smooth muscle contraction mediated by SPC/Fyn/ROK pathway2020
- Author(s)
  Hiroko Kishi, Qian Lu, Tomoka Morita, Ying Zhang, Bochao Lyu, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第97回日本生理学会　3月17日～19日　誌上開催
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] The inhibitory mechanism of T on MDA-MB-231 breast cancer cell migration and the SPC-induced abnormal contraction leading to vasospasm2020
- Author(s)
  Nan Li, Min Zhang, Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  第６２回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Role of paxillin in sphingosylphosphorylcholine (SPC)-induced Ca2+-sensitization contraction of vascular smooth muscle2020
- Author(s)
  Ying Zhang, Bochao Lyu, Tomoka Morita, Dan Cui, Hiroko Kishi, Min Zhang, Qian Lu, Nan Li, Eiji Ikeda, Sei Kobayashi
- Organizer
  第97回日本生理学会　3月17日～19日　誌上開催
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] スフィンゴシルホスホリルコリン（SPC）による血管平滑筋のCa2+感受性収縮におけるパキシリンの役割2020
- Author(s)
  張影、呂博超、森田知佳、崔丹、岸博子、張敏、路倩、李楠、池田栄二、小林誠
- Organizer
  第６２回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 血管平滑筋異常収縮における新規分子パキシリンの関与について2019
- Author(s)
  張　影、呂　博超、森田　知佳、崔　丹、岸　博子、張　敏、路　倩、李　楠、池田　栄二、小林　誠
- Organizer
  2019年11月23～24日、第71回日本生理学会中国四国地方会、山口大学小串キャンパス（医学部）総合研究棟Ａ（医修館）
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 血管平滑筋収縮のCa2+-sensitizationおよびCa2+依存性収縮におけるカルパインの関与2019
- Author(s)
  岸博子、路倩、森田知佳、張影、呂博超、張敏、李楠、小林誠
- Organizer
  2019年8月1 ～3日、第61回日本平滑筋学会総会、名古屋大学　野依記念学術交流館
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Direct Fyn-paxillin binding controls migration of coronary artery smooth muscle cells2019
- Author(s)
  Ying Zhang, Min Zhang, Bochao Lyu, Hiroko Kishi, Tomoka Morita, Qian Lu, Nan Li, Sei Kobayashi
- Organizer
  9th Federation of the Asian and Oceanian Physiological Societies (FAOPS) Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] The involvement of calpain in abnormal vascular smooth muscle contraction induced by SPC and U466192019
- Author(s)
  Hiroko Kishi, Qian Lu, Tomoka Morita, Ying Zhang, Bochao Lyu, Min Zhang, Nan Li, Sei Kobayashi
- Organizer
  9th Federation of the Asian and Oceanian Physiological Societies (FAOPS) Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] The involvement of calpain in abnormal vascular smooth muscle contraction induced by SPC and U466192019
- Author(s)
  Hiroko Kishi, Qian Lu, Tomoka Morita, Ying Zhang, Bochao Lyu, Min Zhang, Nan Li, Sei Kobayashi
- Organizer
  2019年3月28 - 30日、第9回FAOPS大会　神戸コンベンションセンター
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] パキシリンは血管攣縮を制御する新規シグナル分子である2019
- Author(s)
  張　影、呂　博超、森田　知佳、崔　丹、岸　博子、張　敏、路　倩、李　楠、池田　栄二、小林　誠
- Organizer
  2019年8月1～3日、第61回日本平滑筋学会総会、名古屋大学　野依記念学術交流館
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Direct Fyn-paxillin binding controls migration of coronary artery smooth muscle cells.2019
- Author(s)
  Ying Zhang, Min Zhang, Bochao Lyu, Hiroko Kishi, Tomoka Morita, Qian Lu, Nan Li, Sei Kobayashi
- Organizer
  2019年3月28 - 30日、第9回FAOPS大会　神戸コンベンションセンター
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 肺動脈性肺高血圧症に対するエイコサペンタエン酸の改善効果2019
- Author(s)
  倉原琳、平石敬三、張影、山村彩、岸博子、小林誠、井上隆司、平野勝也
- Organizer
  2019年11月23～24日、第71回日本生理学会中国四国地方会、山口大学小串キャンパス（医学部）総合研究棟Ａ（医修館）
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 血管攣縮と癌細胞遊走の両方を阻止できる新規の水溶性食品成分の発見2018
- Author(s)
  浅田充夫、呂博超、張敏、張影、岸博子、森田知佳、小林誠
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] エイコサペンタエン酸（EPA）による肺動脈高血圧病態の改善効果2018
- Author(s)
  倉原琳、平石敬三、張影、山村彩、岸博子、小林誠、井上隆司
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] Compound A suppresses the Fyn/Rho-kinase mediated Ca2+-sensitization of vascular smooth muscle contraction2018
- Author(s)
  Bochao Lyu, Min Zhang, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] The involvement of membrane rafts in the signal transduction of abnormal vascular smooth muscle contraction mediated by SPC/Fyn/ROK pathway: Part II2018
- Author(s)
  Hiroko Kishi, Miki Kajima, Katsuko Kajiya, Ying Zhang, Tomoka Morita, Bochao Lyu, Min Zhang, Sei Kobayashi
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] ドコサペンタエン酸 (DPA)は、n-3とn-6の両系統とも同じ力価で、Rhoキナーゼの細胞内移動と活性化を抑制する事によって血管異常収縮を抑制する2018
- Author(s)
  張影、張　敏、呂　博超、岸博子、森田知佳、路　倩、小林誠
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Fyn-mediated tyrosine phosphorylation of a novel signaling molecule, paxillin controls stress fiber formation and migration of cancer cells2018
- Author(s)
  Shiori Yokobayashi, Ying Zhang, Takafumi Okamoto, Tomoka Morita, Hiroko Kishi, Takeshi Yamamoto, Sei Kobayashi
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] The novel compound from soybean strongly and selectively inhibits the Rho-kinase-mediated Ca2+-sensitization of vascular smooth muscle contraction2018
- Author(s)
  張敏、張影、呂博超、高柿了大、岸博子、加治屋勝子、森田知佳、小林誠
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] 活性型FynチロシンキナーゼのパキシリンN末端への直接結合は血管平滑筋細胞のストレスファイバー形成と細胞遊走を制御する2018
- Author(s)
  張影、岸博子、呂　博超、張　敏、森田知佳、路　倩、小林誠
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 活性型FynチロシンキナーゼのパキシリンN末端への直接結合は血管平滑筋細胞のストレスファイバー形成と細胞遊走を制御する2018
- Author(s)
  張影、岸博子、呂博超、張敏、森田知佳、路倩、小林誠
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] SPC/Fyn/ROK系による血管平滑筋収縮のCa2+-sensitizationにおける、カルパインの役割2018
- Author(s)
  岸博子、張影、森田知佳、呂博超、張敏、路倩、小林誠
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 血管平滑筋のCa2+非依存性収縮と細胞遊走を制御する新規シグナル分子の同定2018
- Author(s)
  張影、松永一真、岡本嵩史、呂博超、張敏、森田知佳、岸博子、小林誠
- Organizer
  筋生理の集い
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] Compound A suppresses the Fyn/Rho-kinase mediated Ca2+-sensitization of vascular smooth muscle contraction2018
- Author(s)
  呂博超、張敏、張影、岸博子、森田知佳、小林誠
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] The novel compound from soybean strongly and selectively inhibits the Rho-kinase-mediated Ca2+-sensitization of vascular smooth muscle contraction.2018
- Author(s)
  Min Zhang, Ying Zhang, Bochao Lyu, Ryodai Takagaki, Hiroko Kishi, Katsuko Kajiya, Tomoka Morita, Sei Kobayashi
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] エイコサペンタエン酸（EPA）による肺動脈高血圧病態の改善効果2018
- Author(s)
  倉原　琳、平石　敬三、張　影、山村　彩、岸　博子、小林　誠、井上　隆司
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Omega-3 and omega-6 docosapentaenoic acid (DPA) equally inhibit the Ca2+-sensitization of abnormal vascular contractions via inhibiting the Rho-kinase activation and translocation.2018
- Author(s)
  Ying Zhang, Min Zhang, Bochao Lyu, Hiroko Kishi, Tomoka Morita, and Sei Kobayashi
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] ドコサペンタ塩酸(DPA)は、n-3とn-6の両系統とも同じ力価で、Rhoキナーゼの細胞内移動と活性化を抑制する事によって血管異常収縮を抑制する2018
- Author(s)
  張影、張敏、呂博超、岸博子、森田知佳、路倩、小林誠
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] Discovery of novel compound from soybean which selectively inhibits the normal vascular contraction leading to vasospasm2018
- Author(s)
  Min Zhang, Ying Zhang, Bochao Lyu, Ryodai Takagaki, Hiroko Kishi, Katsuko Kajiya, Tomoka Morita, Sei Kobayashi
- Organizer
  2018年10月27 - 28日、第70回日本生理学会中国四国地方会、愛媛大学医学部　創立40周年記念講堂　(松山)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] SPC/Fyn/ROK系による血管平滑筋収縮のCa2+-sensitizationにおける、カルパインの役割2018
- Author(s)
  岸博子、張影、森田知佳、呂博超、張敏、路倩、小林誠
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] 血管攣縮と癌細胞遊走の両方を阻止できる新規の水溶性食品成分の発見2018
- Author(s)
  浅田　充夫、呂博超、張敏、張影、岸博子、森田知佳、小林誠
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Tyrosine phosphorylation of paxillin regulates migration and invasion of cancer cells2017
- Author(s)
  Takafumi Okamoto, Ying Zhang, Kazumasa Matsunaga, Shiori Yokobayashi, Tomoka Morita, Hiroko Kishi, Sei Kobayashi
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松 (浜松)
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] Paxillin as a novel signaling molecule regulates actin stress fiber formation and migration of vascular smooth muscle cells by its N-terminus binding to active Fyn2017
- Author(s)
  Ying Zhang, Hiroko Kishi, Katsuko Kajiya, Tomoka Morita, Sei Kobayashi
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松 (浜松)
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] パキシリンはN末端と活性型Fynとの相互作用により血管平滑筋細胞遊走を制御する2017
- Author(s)
  張影、岸博子、森田知佳、呂博超、張敏、横林志織、小林誠
- Organizer
  第59回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] The novel compound from soybean strongly and selectively inhibits the Rho-kinase-mediated Ca2+-sensitization of vascular smooth muscle contraction2017
- Author(s)
  張敏、張影、呂博超、岸博子、加治屋勝子、森田知佳、小林誠
- Organizer
  第59回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] The involvement of membrane rafts in the signal transduction of abnormal vascular smooth muscle contraction mediated by SPC/Fyn/ROK pathway2017
- Author(s)
  Hiroko Kishi, Ying Zhang, Katsuko Kajiya, Tomoka Morita, Bochao Lyu, Min Zhang, Xiaoyan Li, Sei Kobayashi
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松 (浜松)
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] スフィンゴシルホスホリルコリンが誘発する血管平滑筋異常収縮シグナル分子の細胞内局在の変化の検討2017
- Author(s)
  岸博子、張影、加治屋勝子、森田知佳、呂博超、張敏、小林誠
- Organizer
  第59回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] 酸化ストレスにより生じたヒト大動脈平滑筋細胞のカルボニル修飾タンパク質の機能プロテオーム解析2017
- Author(s)
  中村彰男、岸博子、河原田律子、小林誠、小濱一弘
- Organizer
  第59回日本平滑筋学会学術集会
- Data Source
  KAKENHI-PROJECT-15K00809
[Presentation] The novel compound from soybean has a strong inhibitory effect on the Rho-kinase-mediated Ca2+-sensitization of vascular smooth muscle contraction2016
- Author(s)
  張敏、張影、呂博超、岸博子、森田知佳、小林誠
- Organizer
  筋生理の集い
- Place of Presentation
  東京慈恵会医科大学 (東京)
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] Flippase mediates the transmembranous transport of sphingosylphosphorylcholine, a spasmogen of human coronary and cerebral arteries2016
- Author(s)
  Shoko Iwanaga, Hiroko Kishi, Sei Kobayashi
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター (札幌)
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] Analysis of Protein modification by the active ingredient from nicotine- and tar- free cigarette smoke extract.2016
- Author(s)
  Nakamura, A., Kishi, H., Kawaharada, R., Kobayashi, S. and Kohama, K.
- Organizer
  19th International Vascular Biology Meeting
- Place of Presentation
  Boston, U.S.A.
- Year and Date
  2016-10-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00809
[Presentation] Compound X inhibits the ROK-mediated Ca2+-sensitization of vascular smooth muscle contraction induced by a spasmogen, sphingosylphosphorylcholine2016
- Author(s)
  Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  第68回日本生理学会中国四国地方会
- Place of Presentation
  岡山大学Junko Fukutakeホール (岡山)
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] The MLC20 monophosphorylation-dependent and -independent Ca2+-sensitization, respectively at the early and late phase of vascular smooth muscle abnormal contraction2016
- Author(s)
  Hiroko Kishi, Ying Zhang, Tomoka Morita, Bochao Lyu, Min Zhang, Sei Kobayashi
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター (札幌)
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] 血管平滑筋異常収縮を特異的に抑制する食用植物由来成分の探索2015
- Author(s)
  吉井大智、張　影、岸　博子、小林　誠
- Organizer
  第57回日本平滑筋学会総会
- Place of Presentation
  山口大学小串キャンパス(医学部)総合研究棟 (宇部)
- Year and Date
  2015-08-25
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] SPC/Fyn/ROK経路による血管平滑筋収縮Ca2+感受性亢進のシグナル伝達における、ミオシン軽鎖リン酸化の検討2015
- Author(s)
  岸　博子、張　影、呂　博超、張　敏、小林　誠
- Organizer
  第57回日本平滑筋学会総会
- Place of Presentation
  山口大学小串キャンパス(医学部)総合研究棟 (宇部)
- Year and Date
  2015-08-25
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] WASHOKU-modified DASH diet reduces blood pressure and improves cardiovascular risk factors independently of body weight in subjects with untreated high blood pressure and stage 1 hypertension2015
- Author(s)
  A. Kawamura, S. Umemoto, J. Inagaki, H. Kishi, K. Kajiya, M. Mitarai, H. Oda, S. Kobayashi
- Organizer
  ESC Congress 2015
- Place of Presentation
  London (United Kingdom)
- Year and Date
  2015-08-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25450171
[Presentation] Effects of the WASHOKU-modified DASH diet on blood pressure and cardiovascular risk factors among subjects with high normal blood pressure and stage 1 hypertension2015
- Author(s)
  Katsuko Kajiya, Atsuko Kawamura, Hiroko Kishi, Makoto Mitarai, Hiroshi Oda, Seiji Umemoto, Sei Kobayashi
- Organizer
  The 6th International Conference on Food Factor
- Place of Presentation
  Seoul (Korea)
- Year and Date
  2015-11-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25450171
[Presentation] 活性化FynとパキシリンN末端との相互作用は血管平滑筋細胞のストレスファイバー形成と細胞遊走において重要な役割を担う2015
- Author(s)
  張　影、岸　博子、加治屋勝子、呂　博超、張　敏、森田　智佳、小林　誠
- Organizer
  第57回日本平滑筋学会総会
- Place of Presentation
  山口大学小串キャンパス(医学部)総合研究棟 (宇部)
- Year and Date
  2015-08-25
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] Docosapentaenoic acid (DPA) n-6 不飽和脂肪酸により新たな血管攣縮の抑制作用の発見とその分子機構の解明2015
- Author(s)
  張　影、張　敏、呂　博超、岸　博子、小林　誠
- Organizer
  第67回日本生理学会中国四国地方会
- Place of Presentation
  米子コンベンションセンター小ホール (米子)
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] Effects of the Washoku-modified DASH diet on blood pressure and cardiometabolic risk factors in subjects with untreated high normal blood pressure and stage 1 hypertension2015
- Author(s)
  S. Umemoto, A. Kawamura, J. Inagaki, H. Kishi, K. Kajiya, M. Mitarai, K. Oda, S. Kobayashi
- Organizer
  25th European Meeting on Hypertension and Cardiovascular Protection
- Place of Presentation
  Milan(Italy)
- Year and Date
  2015-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25450171
[Presentation] 血管平滑筋収縮のカルシウム感受性亢進における、タンパク質分解酵素の関与の可能性2014
- Author(s)
  岸　博子、張　影、宮成健司、木村友彦、高柿了大、呂　博超、小林　誠
- Organizer
  筋生理の集い
- Place of Presentation
  東京慈恵会医科大学 (東京都)
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] The time course of Fyn and ROK activation in the signal transduction of abnormal vascular smooth muscle contraction2014
- Author(s)
  Hiroko Kishi, Ying Zhang, Ryodai Takagaki, Kenji Miyanari, Tomohiko Kimura, Sei Kobayashi
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学郡元キャンパス(鹿児島)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] Important role of cell membrane microdomain for Ca2+-sensitization of vascular smooth muscle contraction2014
- Author(s)
  Katsuko Kajiya, Kazutaka Nojimoto, Hiroko Kishi, Yuichi Takada, Ying Zhang, Sei Kobayashi
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学郡元キャンパス(鹿児島)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] 血管異常収縮の新規シグナル分子として同定された細胞骨格関連因子のFynとの相互作用解析2013
- Author(s)
  岸博子（研究代表者は3番目）
- Organizer
  第55回日本平滑筋学会
- Place of Presentation
  大雪クリスタルホール(旭川）
- Data Source
  KAKENHI-PROJECT-25450171
[Presentation] The characterization of a cytoskeleton-related protein identified as the novel downstream target of Fyn in SPC/Fyn/ROK pathway mediating abnormal vascular smooth muscle contraction2013
- Author(s)
  Hiroko Kishi
- Organizer
  The 90th Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  タワーホール船堀(東京)
- Data Source
  KAKENHI-PROJECT-22500364
[Presentation] 血管平滑筋アクチン・ストレスファイバーの形成を担う新規シグナル分子の同定とその機能解析2013
- Author(s)
  張　影、岸　博子、加治屋勝子、宮成健司、木村友彦、小林　誠
- Organizer
  第55回日本平滑筋学会総会
- Place of Presentation
  旭川市大雪クリスタルホール(旭川)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] The interaction of Fyn and a cytoskeleton-related protein which is identified as a novel signaling molecule in SPC/Fyn/ROK pathway to mediate abnormal VSM contraction2013
- Author(s)
  Hiroko Kishi, Ying Zhang, Katsuko Kajiya, Tomohiko Kimura, Kenji Miyanari, Sei Kobayashi
- Organizer
  第36回心筋代謝研究会
- Place of Presentation
  キヤノンマーケティングジャパン株式会社 3階ホール(東京)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] 血管異常収縮の新規シグナル分子として同定された細胞骨格関連分子の、Fynとの相互作用解析2013
- Author(s)
  岸　博子、張　影、加治屋勝子、高田雄一、宮成健司、木村友彦、野地本和孝、小林　誠
- Organizer
  第55回日本平滑筋学会総会
- Place of Presentation
  旭川市大雪クリスタルホール(旭川)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] 冠血管弛緩作用を有する新規ペプチドの探索: 続報2013
- Author(s)
  木村友彦、宮成健司、高柿了大、張影、岸博子、小林誠
- Organizer
  筋生理の集い
- Place of Presentation
  東京慈恵会医科大学(東京)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] 血管平滑筋異常収縮の病的シグナル伝達における細胞膜上マイクロドメインの新規機能2013
- Author(s)
  加治屋勝子、野地本和孝、岸　博子、張　影、高田雄一、木村友彦、宮成健司、小林　誠
- Organizer
  第55回日本平滑筋学会総会
- Place of Presentation
  旭川市大雪クリスタルホール(旭川)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] The characterization of a cytoskeleton-related protein identified as the novel downstream target of Fyn in SPC/Fyn/ROK pathway mediating abnormal vascular smooth muscle contraction2013
- Author(s)
  Hiroko Kishi
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  タワーホール船堀(東京)
- Data Source
  KAKENHI-PROJECT-22500364
[Presentation] The development of a high-throughput and objective screening system to validate candidate molecules for downstream target of Fyn in SPC/Fyn/ROK pathway which mediates abnormal vascular smooth muscle contraction2012
- Author(s)
  Hiroko Kishi
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  長野県松本文化会館(松本) ※ポスターアワード受賞
- Data Source
  KAKENHI-PROJECT-22500364
[Presentation] The development of a high-throughput and objective screening system to validate candidate molecules which mediate abnormal vascular smooth muscle contraction2012
- Author(s)
  Hiroko Kishi
- Organizer
  第35回心筋代謝研究会
- Place of Presentation
  キャノンマーケティングジャパン株式会社(東京)
- Data Source
  KAKENHI-PROJECT-22500364
[Presentation] The development of a high-throughput and objective screening system to validate candidate molecules for downstream target of Fyn in SPC/Fyn/ROK pathway which mediates abnormal vascular smooth muscle contraction2012
- Author(s)
  岸博子
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  長野県松本文化会館(松本市)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-22500364
[Presentation] 血管平滑筋異常収縮新規シグナル候補分子の絞込みのための、自動細胞イメージングシステムによる、ハイスループットかつ定量的なスクリーニング系の開発2012
- Author(s)
  岸　博子
- Organizer
  第54回日本平滑筋学会
- Place of Presentation
  東京慈恵会医科大学大学1号館講堂(東京)
- Data Source
  KAKENHI-PROJECT-22500364
[Presentation] 自動細胞イメージングシステムを用いた、血管平滑筋異常収縮の新規シグナル分子探索の客観的ハイスループット化2011
- Author(s)
  岸博子
- Organizer
  第53回日本平滑筋学会総会
- Place of Presentation
  ゆうぽうと(東京都)
- Year and Date
  2011-08-03
- Data Source
  KAKENHI-PROJECT-22500364
[Presentation] 自動細胞イメージングシステムを用いた、血管平滑筋異常収縮の新規シグナル分子探索の客観的ハイスループット化2011
- Author(s)
  岸博子
- Organizer
  第53回日本平滑筋学会
- Place of Presentation
  ゆうぽうと(東京)
- Data Source
  KAKENHI-PROJECT-22500364
[Presentation] Focused Proteomics による、血管平滑筋異常収縮の新規病的シグナル分子の探索2010
- Author(s)
  岸博子
- Organizer
  第52回日本平滑筋学会
- Place of Presentation
  仙台市情報・産業プラザ(仙台)
- Data Source
  KAKENHI-PROJECT-22500364
[Presentation] Focused Proteomicsによる、血管平滑筋異常収縮の新規病的シグナル分子の探索2010
- Author(s)
  岸博子
- Organizer
  第52回日本平滑筋学会総会
- Place of Presentation
  宮城県仙台市仙台市情報・産業プラザ
- Year and Date
  2010-07-02
- Data Source
  KAKENHI-PROJECT-22500364
[Presentation] Focused proteomic approach to identify novel signaling molecules for abnormal vascular smooth muscle contraction2010
- Author(s)
  Hiroko Kishi
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市民文化ホール等 (盛岡)
- Data Source
  KAKENHI-PROJECT-22500364
[Presentation] 血管平滑筋収縮のCa^<2+>-sensitizationを特異的に阻害する植物由来成分2010
- Author(s)
  宮成健司、野地本和孝、岸博子、加治屋勝子、高田雄一、小林誠
- Organizer
  筋生理の集い
- Place of Presentation
  東京, 東京慈恵会医科大学
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-22580131
[Presentation] 質量分析装置を用いたミオシン軽鎖キナーゼのリン酸化部位の決定2008
- Author(s)
  中村彰男, 岸博子, 松本篤, 石川良樹, 吉山伸司, 早川晃一, 小林誠, 小濱一弘
- Organizer
  第118回薬理学会関東部会・第10回応用薬理シンポジウム
- Place of Presentation
  東京(星薬科大)
- Data Source
  KAKENHI-PROJECT-19590240
[Presentation] 質量分析装置を用いたミオシン軽鎖キナーゼのリン酸化部位の決定2008
- Author(s)
  中村彰男、岸博子、松本篤、石川良樹、吉山伸司、早川晃一、小林誠、小濱一弘
- Organizer
  第118回薬理学会関東部会
- Place of Presentation
  東京(星薬科大)
- Data Source
  KAKENHI-PROJECT-19590240
[Presentation] セリン・スレオニンキナーゼによるコンビナントミオシン軽鎖キナーゼのリン酸化部位の決定2007
- Author(s)
  中村彰男, 岸博子, 松本篤, 小林誠, 小濱一弘
- Organizer
  15^<th> 日本血管生物医学会学術大会
- Place of Presentation
  Fukuoka
- Data Source
  KAKENHI-PROJECT-19590240
[Presentation] Determination of phosphorylation site of smooth muscle myosin light chain kinase by various Ser/Thr kinases2007
- Author(s)
  Nakamura, A., Kishi, H., Matsumoto, A., Ishikawa, R., Kobayashi, S., Kohama, K.
- Organizer
  Joint meeting of the 40th Japanese Society of Developmental Biologists & the 59th Japan Society for Cell Biology
- Place of Presentation
  Fukuoka
- Data Source
  KAKENHI-PROJECT-19590240
[Presentation] SPC/Fyn/ROK経路による血管平滑筋収縮Ca2+感受性亢進のシグナル伝達における、FynおよびROK活性化の経時的変化の検討
- Author(s)
  岸　博子、張　影、宮成健司、木村友彦、高柿了大、呂　博超、小林　誠
- Organizer
  第56回日本平滑筋学会総会
- Place of Presentation
  新横浜プリンスホテル (横浜市)
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] Discovery of novel Salacia-derived components which specifically inhibit the ROK-mediated Ca2+-sensitization of vascular smooth muscle contraction
- Author(s)
  Kenji Miyanari, Kazutaka Nojimoto, Katsuko Kajiya, Yuichi Takada, Tomohiko Kimura, Ying Zhang, Hiroko Kishi, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] パキシリンのN末端は活性型Fynチロシンキナーゼとの結合によりストレスファイバー形成を制御する
- Author(s)
  張影、岸博子、宮成健司、木村友彦、高柿了大、加治屋勝子、小林誠
- Organizer
  第120回日本解剖学会・第92回日本生理学会合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県、神戸市）
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25450171
[Presentation] 正常高値血圧及びⅠ度高血圧者のための日本人向けDASH食事療法「DASH-JUMP」の食生活における行動変容への影響
- Author(s)
  河村敦子、稲垣順子、加治屋勝子、岸博子、梅本誠治、御手洗誠、織田浩司、小林誠
- Organizer
  第37回日本高血圧学会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2014-10-17 – 2014-10-19
- Data Source
  KAKENHI-PROJECT-25450171
[Presentation] N-terminus of paxillin regulates actin stress fiber formation by binding to the active Fyn
- Author(s)
  Ying Zhang, Hiroko Kishi, Kenji Miyanari, Tomohiko Kimura, Ryodai Takagaki, Bochao Lyu, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-23659113
[Presentation] アクチン・ストレスファイバー形成における、新規シグナル分子パキシリンと活性型Fynチロシンキナーゼとの相互作用の重要性
- Author(s)
  張影、岸博子、宮成健司、木村友彦、高柿了大、呂博超、小林誠
- Organizer
  第５６回日本平滑筋学会
- Place of Presentation
  新横浜プリンスホテル（横浜市）
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-25893150
[Presentation] Novel fish-derived peptide fragments which induce endothelium-dependent and -independent vasorelaxation
- Author(s)
  Tomohiko Kimura, Yuichi Takada, Katsuko Kajiya, Ying Zhang, Kenji Miyanari, Hiroko Kishi, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] The novel role of calpain in SPC/Fyn/ROK pathway which mediates the signal transduction of abnormal vascular smooth muscle contraction
- Author(s)
  Hiroko Kishi, Ying Zhang, Kenji Miyanari, Tomohiko Kimura, Ryodai Takagaki, Bochao Lyu, Sei Kobayashi
- Organizer
  第１２０回日本解剖学会総会・全国学術集会/第９２回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場（神戸市）
- Year and Date
  2015-03-20 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25893150
[Presentation] アクチン・ストレスファイバー形成における、新規シグナル分子パキシリンと活性型Fynチロシンキナーゼとの相互作用の重要性
- Author(s)
  張　影、岸　博子、宮成健司、木村友彦、高柿了大、呂　博超、小林　誠
- Organizer
  第56回日本平滑筋学会総会
- Place of Presentation
  新横浜プリンスホテル (横浜市)
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-23659113
[Presentation] アクチン・ストレスファイバー形成における、新規シグナル分子パキシリンと活性型Fynチロシンキナーゼとの相互作用の重要性
- Author(s)
  張　影、岸　博子、宮成健司、木村友彦、高柿了大、呂　博超、小林　誠
- Organizer
  第56回日本平滑筋学会総会
- Place of Presentation
  新横浜プリンスホテル (横浜市)
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-23380077
[Presentation] Discovery of novel Salacia-derived components which specifically inhibit the ROK-mediated Ca2+- sensitization of vascular smooth muscle contraction
- Author(s)
  Kenji Miyanari, Kazutaka Nojimoto, Katsuko Kajiya, Yuichi Takada, Tomohiko Kimura, Ying Zhang, Hiroko Kishi, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-23659113
[Presentation] 血管平滑筋におけるRhoキナーゼを介在したカルシウム感受性亢進を特異的に阻害する新規のサラシア由来成分の探索
- Author(s)
  宮成健司、野地本和孝、加治屋勝子、高田雄一、木村友彦、張影、岸博子、小林誠
- Organizer
  第120回日本解剖学会・第92回日本生理学会合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県、神戸市）
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25450171
[Presentation] N-terminus of paxillin regulates actin stress fiber formation by binding to the active Fyn
- Author(s)
  Ying Zhang, Hiroko Kishi, Kenji Miyanari, Tomohiko Kimura, Ryodai Takagaki, Bochao Lyu, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] FABP7 is involved in epigenetic modification of mouse caveolin-1 gene promotor
- Author(s)
  Yoshiteru Kagawa, Hiroshi Kogo, Hiroko Kishi, Sei Kobayashi, Toyoshi Fujimoto
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] Novel fish-derived peptide fragments which induce endothelium-dependent and -independent vasorelaxation
- Author(s)
  Tomohiko Kimura, Yuichi Takada, Katsuko Kajiya, Ying Zhang, Kenji Miyanari, Hiroko Kishi, Sei Kobayashi
- Organizer
  第１２０回日本解剖学会総会・全国学術集会/第９２回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場（神戸市）
- Year and Date
  2015-03-20 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25893150
[Presentation] Discovery of novel Salacia-derived components which specifically inhibit the ROK-mediated Ca2+-sensitization of vascular smooth muscle contraction
- Author(s)
  Kenji Miyanari, Kazutaka Nojimoto, Katsuko Kajiya, Yuichi Takada, Tomohiko Kimura, Ying Zhang, Hiroko Kishi, Sei Kobayashi
- Organizer
  第１２０回日本解剖学会総会・全国学術集会/第９２回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場（神戸市）
- Year and Date
  2015-03-20 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25893150
[Presentation] N-terminus of paxillin regulates actin stress fiber formation by binding to the active Fyn
- Author(s)
  Ying Zhang, Hiroko Kishi, Kenji Miyanari, Tomohiko Kimura, Ryodai Takagaki, Bochao Lyu, Katsuko Kajiya, Sei Kobayashi
- Organizer
  第１２０回日本解剖学会総会・全国学術集会/第９２回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場（神戸市）
- Year and Date
  2015-03-20 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25893150
[Presentation] アクチン・ストレスファイバー形成における、新規シグナル分子パキシリンと活性型Fynチロシンキナーゼとの相互作用の重要性
- Author(s)
  張　影、岸　博子、宮成健司、木村友彦、高柿了大、呂　博超、小林　誠
- Organizer
  第56回日本平滑筋学会総会
- Place of Presentation
  新横浜プリンスホテル (横浜市)
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] SPC/Fyn/ROK経路による血管平滑筋収縮Ca2+感受性亢進のシグナル伝達における、FynおよびROK活性化の経時的変化の検討
- Author(s)
  岸博子、張影、宮成健司、木村友彦、高柿了大、呂博超、小林誠
- Organizer
  第５６回日本平滑筋学会
- Place of Presentation
  新横浜プリンスホテル（横浜市）
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-25893150
[Presentation] 内皮依存性、非依存性血管弛緩作用を有する魚類由来ペプチド
- Author(s)
  木村友彦、高田雄一、加治屋勝子、張影、宮成健司、岸博子、小林誠
- Organizer
  第120回日本解剖学会・第92回日本生理学会合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県、神戸市）
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25450171
[Presentation] Effects of the Washoku-modified DASH diet on blood pressure and cardiometabolic risk factors in subjects with untreated high normal blood pressure and stage 1 hypertension
- Author(s)
  S. Umemoto, A. Kawamura, J. Inagaki, H. Kishi, K. Kajiya, M. Mitarai, K. Oda, S. Kobayashi
- Organizer
  25th European Meeting on Hypertension and Cardiovascular Protection
- Place of Presentation
  Mico Milano Congressi (Milan, Italy)
- Year and Date
  2015-06-12 – 2015-06-15
- Data Source
  KAKENHI-PROJECT-25450171
[Presentation] WASHOKU-modified DASH diet reduces blood pressure and improves cardiometabolic risk factors independently of body weight in subjects with untreated high normal blood pressure and stage 1 hypertension
- Author(s)
  A. Kawamura, S. Umemoto, J. Inagaki, H. Kishi, K. Kajiya, M. Mitarai, K. Oda, S. Kobayashi
- Organizer
  ESC Congress 2015
- Place of Presentation
  ExCeL London (London, United Kingdom)
- Year and Date
  2015-08-29 – 2015-09-02
- Data Source
  KAKENHI-PROJECT-25450171
[Presentation] N-terminus of paxillin regulates actin stress fiber formation by binding to the active Fyn
- Author(s)
  Ying Zhang, Hiroko Kishi, Kenji Miyanari, Tomohiko Kimura, Ryodai Takagaki, Bochao Lyu, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-23380077
[Presentation] The novel role of calpain in SPC/Fyn/ROK pathway which mediates the signal transduction of abnormal vascular smooth muscle contraction
- Author(s)
  Hiroko Kishi, Ying Zhang, Kenji Miyanari, Tomohiko Kimura, Ryodai Takagaki, Bochao Lyu, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] Discovery of novel Salacia-derived components which specifically inhibit the ROK-mediated Ca2+- sensitization of vascular smooth muscle contraction
- Author(s)
  Kenji Miyanari, Kazutaka Nojimoto, Katsuko Kajiya, Yuichi Takada, Tomohiko Kimura, Ying Zhang, Hiroko Kishi, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-23380077

1. KOBAYASHI Sei (80225515)

# of Collaborated Projects: 16 results

# of Collaborated Products: 138 results
2. KAJIYA Katsuko (00379942)

# of Collaborated Projects: 7 results

# of Collaborated Products: 29 results
3. ZHANG Ying (10711260)

# of Collaborated Projects: 7 results

# of Collaborated Products: 109 results
4. NAKAMURA Akio (30282388)

# of Collaborated Projects: 5 results

# of Collaborated Products: 9 results
5. 森田知佳 (70763796)

# of Collaborated Projects: 4 results

# of Collaborated Products: 74 results
6. KAWAMICHI Hozumo (80363042)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
7. KOHAMA Kazuhiro (30101116)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
8. MOGAMI Kimiko (80263771)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. ISHIKAWA Ryoki (20212863)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
10. 佐藤正史 (20346547)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 河原田律子 (60383147)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
12. 松崎健太郎 (90457185)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. OKAGAKI Tsuyoshi (80185412)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. 片倉賢紀 (40383179)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 杉本直俊 (80272954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 前嶋翔 (10773286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 宮本達雄 (40452627)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 大日方英 (50332557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. LYU Bochao

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
20. ZHANG Min

# of Collaborated Projects: 1 results

# of Collaborated Products: 23 results
21. LU Qian

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
22. LI Nan

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
23. KAWAMURA Atsuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. UMEMOTO Seiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. MITARAI Makoto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 佐藤元彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 山村彩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 永野浩昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 恒富亮一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 前田訓子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 堀正敏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 尾崎博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kishi Hiroko 岸 博子

KISHI Hiroko 岸 博子

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ビメンチン断片化が起こす血管平滑筋の異常収縮機構の解明と予防治療法の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the novel signaling pathway of vimentin-mediated abnormal vascular smooth muscle contractionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the involvement of calpain and cytoskeletal proteins in the signal transduction of abnormal vascular smooth muscle contractionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the shared signaling pathways for intractable diseases in terms of cytoskeletal rearrangementsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The elucidation of the relationship between vascular smooth muscle contraction and cytoskeletal rearrangement by proteomics and functional analysisPrincipal Investigator

Kishi Hiroko 岸博子

KISHI Hiroko 岸博子