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TOSHIMASA Yamazaki  山崎 俊正

ORCIDConnect your ORCID iD *help
… Alternative Names

YAMAZAKI Toshimasa  山崎 俊正

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Researcher Number 40360458
Other IDs
Affiliation (based on the past Project Information) *help 2021: 国立研究開発法人農業・食品産業技術総合研究機構, 高度分析研究センター, 所長・部門長
2019 – 2020: 国立研究開発法人農業・食品産業技術総合研究機構, 高度解析センター, 所長・部門長
2017: 国立研究開発法人農業・食品産業技術総合研究機構, 高度解析センター, センター長
2016 – 2017: 国立研究開発法人農業・食品産業技術総合研究機構, 高度解析センター, チーム長
2016: 国立研究開発法人農業・食品産業技術総合研究機構, 高度解析センター・生体高分子解析チーム, チーム長 … More
2016: 国立研究開発法人農業生物資源研究所, その他部局等, ユニット長
2015: 国立研究開発法人農業生物資源研究所, 生体分子研究ユニット, ユニット長
2014: 独立行政法人農業生物資源研究所, 先端ゲノム研究センター, 生体分子研究ユニット長
2013 – 2014: 独立行政法人農業生物資源研究所, 生体分子研究ユニット, ユニット長
2013: 独立法人農業生物資源研究所, 農業生物先端ゲノム研究センター, ユニット長
2013: 独立行政法人農業生物資源研究所, その他部局等, その他
2012: 独立行政法人農業生物資源研究所, その他部局等, ユニット長
2011 – 2012: 独立行政法人農業生物資源研究所, その他部局等, 研究員
2011: 独立行政法人農業生物資源研究所, 生体分子研究ユニット, ユニット長
2008 – 2009: National Institute of Agrobiological Sciences, タンパク質機能研究ユニット, ユニット長
2007: National Institute of Agrobiological Sciences, 植物科学研究領域・タンパク質機能研究ユニット, ユニット長
2006: Kyoto Pharmaceutical University, Team Leader
2004 – 2005: 独立行政法人農業生物資源研究所, 主任研究官 Less
Review Section/Research Field
Principal Investigator
Structural biochemistry / Food Cycle Research
Except Principal Investigator
Applied entomology / Basic Section 38060:Applied molecular and cellular biology-related / Plant protection science / Environmental impact assessment / Drug development chemistry / Insect science
Keywords
Principal Investigator
構造生物学 / SUMO化翻訳後修飾 / 分子認識 / 蛋白質 / 生物物理 / 分子標的硝化抑制剤 / 構造ベース創農薬 / 分子標的型硝化抑制剤 / 地球温暖化ガス排出削減 / 環境調和型農林水産 … More / SUMO化酵素 / 構造生理学 / ヒストン認識 / DNA結合 / SUMOリガーゼ … More
Except Principal Investigator
種子休眠 / アブシジン酸 / 植物 / プロテオーム / シグナル伝達 / 活性増強効果 / 植物ー昆虫相互作用 / 耐虫性タンパク質 / 相乗効果 / 植物耐虫効果 / 相乗 / ポトス / キチナーゼ / ヤマノイモ / 相乗的耐虫効果 / シュウ酸カルシウム針状結晶 / 酵素反応 / 脂質 / ハイスループットスクリーニング / 糖脂質合成酵素 / 膜貫通タンパク質 / 阻害剤 / シアノバクテリア / ガラクト脂質 / チラコイド膜 / HTLV-1 protease / adult T-cell leukemia / plasmepsin / β-secretase / Alzheimer's disease / aspartic protease / enzyme inhibitors / 難病治療薬 / ドラッグデザイン / 分子認識 / マラリア / HIVプロテアーゼ / セクレターゼ / HTLV-1プロテアーゼ / 成人T細胞白血病 / プラスメプシン / β-セクレターゼ / アルツハイマー病 / アスパラギン酸プロテアーゼ / 酵素阻害剤 / 核多角体病ウイルス / プロテアーゼ / スピンドル / 昆虫ポックスウイルス / 囲食膜 / フゾリン / 害虫 / 分解酵素 / フェロモン / 化学交信 / タンパク質 / カイコ蛾 / カイコ我 / フェロモン分解酵素 / アルコールデハイドロゲナーゼ / アルコールオキシダーゼ / フェロモン分解 / 大量精製 / 組換えタンパク質 / 塩基配列決定 / 組織局在性 / Niemann-Pick Type C-2 / クロオオアリ / 円偏光偏光二色性 / Niemann-Pick Type C2 / 情報伝達物質 / 結晶化学 / GC-EAD / 円偏光二色性 / 蛍光拮抗アッセイ / クロオオアリワーカー / ニーマンピック2型タンパク質 Less
  • Research Projects

    (10 results)
  • Research Products

    (26 results)
  • Co-Researchers

    (21 People)
  •  Elucidation of the functional molecular mechanisms of seed dormancy mediated by abscisic acid

    • Principal Investigator
      Nishimura Noriyuki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 38060:Applied molecular and cellular biology-related
    • Research Institution
      National Agriculture and Food Research Organization
  •  Development of a specific growth inhibitor for cyanobacteria, targeting the pathway for a photosynthetic membrane lipid.

    • Principal Investigator
      Awai Koichiro
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Environmental impact assessment
    • Research Institution
      Shizuoka University
  •  Researches on synergistic defensive function of raphides and other defensive substances

    • Principal Investigator
      Konno Kotaro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Plant protection science
    • Research Institution
      National Agriculture and Food Research Organization
      国立研究開発法人農業生物資源研究所
  •  Structure-based design of nitrification inhibitor targeting hydroxylamine oxidoreductases of ammonia-oxidizing bacteriaPrincipal Investigator

    • Principal Investigator
      Toshimasa Yamazaki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Food Cycle Research
    • Research Institution
      National Agriculture and Food Research Organization
      National Institute of Agrobiological Sciences
  •  Study on the development of the efficient use of the protein fusolin targetting the insect peritophic matrix for pest control

    • Principal Investigator
      MITSUHASHI Wataru
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Insect science
    • Research Institution
      National Agriculture and Food Research Organization
      National Institute of Agrobiological Sciences
  •  PDE analysis

    • Principal Investigator
      MIYAZAWA mitsuhiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied entomology
    • Research Institution
      National Institute of Agrobiological Sciences
  •  Roles of Multiple-Binding Sites of Conjugating Enzyme E2 in SUMOylationPrincipal Investigator

    • Principal Investigator
      TOSHIMASA Yamazaki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      National Institute of Agrobiological Sciences
  •  Characterization of antenna-specific cholesterol-binding protein in the ant

    • Principal Investigator
      ISHIDA Yuko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied entomology
    • Research Institution
      Toyama Prefectural University
      Kobe University
  •  Structures and Functions of the N-terminal Domains of SUMO Ligase PIAS/Siz FamilyPrincipal Investigator

    • Principal Investigator
      YAMAZAKI Toshimasa
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      National Institute of Agrobiological Sciences
  •  Design and development of therapeutic drugs for intractable diseases based on molecular recognition of aspartic proteases

    • Principal Investigator
      KISO Yoshiaki
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Drug development chemistry
    • Research Institution
      Kyoto Pharmaceutical University

All 2022 2019 2017 2016 2014 2012 2011 2009 2007 Other

All Journal Article Presentation Patent

  • [Journal Article] New Mechanism of Abscisic Acid Signaling Cascade: Survival Strategy for Plants to Adapt to Growing Environmental Change2019

    • Author(s)
      西村宜之、土屋渉、平山隆志、山崎俊正
    • Journal Title

      KAGAKU TO SEIBUTSU

      Volume: 57 Issue: 12 Pages: 736-742

    • DOI

      10.1271/kagakutoseibutsu.57.736

    • NAID

      130007948472

    • ISSN
      0453-073X, 1883-6852
    • Year and Date
      2019-12-01
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-19H02925
  • [Journal Article] Optimized inhibition assays reveal different inhibitory responses of hydroxylamine oxidoreductases from beta- and gamma-proteobacterial ammonium-oxidizing bacteria2016

    • Author(s)
      Yuki Nishigaya, Zui Fujimoto, Toshimasa Yamazaki
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 476 Issue: 3 Pages: 127-133

    • DOI

      10.1016/j.bbrc.2016.05.041

    • NAID

      120006358564

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26310317
  • [Journal Article] Niemann-Pick type C2 protein mediating chemical communication in the worker ant2014

    • Author(s)
      Ishida, Y., Tsuchiya, W., Fujii, T., Fujimoto, Z., Miyazawa, M., Ishibashi, J., Matsuyama, S., Ishikawa, Y., and Yamazaki, T
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 111 Issue: 10 Pages: 3847-3852

    • DOI

      10.1073/pnas.1323928111

    • Data Source
      KAKENHI-PROJECT-23580070
  • [Journal Article] PHD finger of the SUMP ligase Siz/PIAS family in rice reveals specific binding for methylated histone H3 at lysine 4 and arginine 22012

    • Author(s)
      H. Shindo, R. Suzuki, W. Tsuchiya, M. Taichi, Y. Nishiuchi, T. Yamazaki
    • Journal Title

      FEBS Letters

      Volume: 586(13) Issue: 13 Pages: 1783-1789

    • DOI

      10.1016/j.febslet.2012.04.063

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570151
  • [Journal Article] PHD finger of the SUMO ligase Siz/PIAS family in rice reveals specific binding for methylated histone H3 at lysine 4 and arginine 22012

    • Author(s)
      Shindo H, Suzuki R, Tsuchiya W, Taichi M, Nishiuchi Y, Yamazaki T.
    • Journal Title

      FEBS Letters.

      Volume: 586(13) Pages: 1783-1789

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570151
  • [Journal Article] NMR Assignments of Ubiquitin Fold Domain (UFD) in SUMO-activating Enzyme Subunit 2 from Rice2011

    • Author(s)
      R. Suzuki, W. Tsuchiya, H. Shindo, T. Yamazaki
    • Journal Title

      Biomolecular NMR Assignments

      Volume: 5(2) Pages: 245-248

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570151
  • [Journal Article] NMR assignments of ubiquitin fold domain (UFD) in SUMO-activating enzyme subunit 2 from rice2011

    • Author(s)
      Suzuki R, Tsuchiya W, Shindo H, Yamazaki T.
    • Journal Title

      Biomolecular NMR Assignments

      Volume: 5(2) Pages: 245-248

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570151
  • [Journal Article] Solution structures and DNA binding properties of the N-terminal SAP domains of SUMO E3 ligases from Saccharomyces cerecisiae and Oryza sativa2009

    • Author(s)
      Suzuki R, Shindo H, Tase A, Kikuchi Y, Shimizu M, Yamazaki T
    • Journal Title

      Proteins 75(2)

      Pages: 336-347

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570115
  • [Journal Article] Solution structures and DNA binding properties of the N-terminal SAP domains of SUMO E3 ligases from Saccharomyces cervisiae and Oryza sativa.2009

    • Author(s)
      Suzuki R, Shindo H, Tase A, Kikuchi Y, Shimizu M, Yamazaki T
    • Journal Title

      PROTEINS 75(2)

      Pages: 336-347

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570115
  • [Patent] 酸化還元酵素の活性測定方法2022

    • Inventor(s)
      山崎俊正, 西ヶ谷 有輝
    • Industrial Property Rights Holder
      国立研究開発法人農業・食品産業技術総合研究機構
    • Industrial Property Rights Type
      特許
    • Acquisition Date
      2022
    • Data Source
      KAKENHI-PROJECT-26310317
  • [Patent] 酸化還元酵素の活性測定方法2017

    • Inventor(s)
      山崎俊正, 西ヶ谷有輝
    • Industrial Property Rights Holder
      国立研究開発法人農業・食品産業技術総合研究機構
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017-01-18
    • Acquisition Date
      2018-01-12
    • Data Source
      KAKENHI-PROJECT-26310317
  • [Patent] 酸化還元酵素の活性測定方法2017

    • Inventor(s)
      山崎俊正、西ヶ谷有輝
    • Industrial Property Rights Holder
      山崎俊正、西ヶ谷有輝
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017-01-18
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26310317
  • [Patent] テトラゾリウム塩の存在下でヒドロキシルアミン酸化還元酵素と接触させることを含む、ヒドロキシルアミン酸化還元酵素の活性測定方法2016

    • Inventor(s)
      山崎俊正、西ヶ谷有輝
    • Industrial Property Rights Holder
      山崎俊正、西ヶ谷有輝
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-010983
    • Filing Date
      2016-01-22
    • Data Source
      KAKENHI-PROJECT-26310317
  • [Presentation] ヒドロキシルアミン酸化還元酵素を標的とした硝化抑制剤の構造ベース創農薬2017

    • Author(s)
      西ヶ谷有輝、土屋渉、藤本瑞、山崎俊正
    • Organizer
      日本農薬学会42回大会
    • Place of Presentation
      愛媛大学(愛媛県・松山市)
    • Year and Date
      2017-03-06
    • Data Source
      KAKENHI-PROJECT-26310317
  • [Presentation] Structure analysis of target proteins applied to BNI action mechanism research2016

    • Author(s)
      Yuki Nishigaya, Toshimasa Yamazaki
    • Organizer
      BNI International Symposium
    • Place of Presentation
      つくば国際会議場(茨城県・つくば市)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26310317
  • [Presentation] 持続的農業に貢献する硝化抑制剤の創農薬2016

    • Author(s)
      西ヶ谷有輝、藤本瑞、土屋渉、山崎俊正
    • Organizer
      第7回スクリーニング学研究会
    • Place of Presentation
      タワーホール船堀(東京都・江戸川区)
    • Data Source
      KAKENHI-PROJECT-26310317
  • [Presentation] クロオオアリワーカー触角特異的ヒトコレステロール結合タンパク質類似タンパク質の同定、発現、性状解析2012

    • Author(s)
      石田裕幸・土屋渉・石橋純・宮澤光博・山崎俊正
    • Organizer
      日本蚕糸学会平成24年度蚕糸・昆虫機能利用学術講演会
    • Place of Presentation
      九州大学箱崎キャンパス文系地区
    • Data Source
      KAKENHI-PROJECT-23580070
  • [Presentation] クロオオアリワーカー触角特異的ヒトコレステロール結合タンパク質類似タンパク質の同定、発現、性状2012

    • Author(s)
      石田裕幸・土屋渉・石橋純・宮澤光博・山崎俊正
    • Organizer
      平成24年度蚕糸・昆虫機能利用学術講演会
    • Place of Presentation
      九州大学箱崎キャンパス文系地区
    • Data Source
      KAKENHI-PROJECT-23580070
  • [Presentation] SUMOリガーゼSiz/PIASファミリーの構造と機能に関する研究2009

    • Author(s)
      山崎俊正
    • Organizer
      第7回SUMO研究会
    • Place of Presentation
      兵庫県三田市
    • Year and Date
      2009-11-22
    • Data Source
      KAKENHI-PROJECT-19570115
  • [Presentation] NMR structures and self-sumoylation of the N-terminal SAP domains of SUMO ligase PIAS/Siz family2007

    • Author(s)
      Suzuki R, Shindo H, Tase A Yamazaki T
    • Organizer
      第47回NMR討論会
    • Place of Presentation
      札幌
    • Year and Date
      2007-09-13
    • Data Source
      KAKENHI-PROJECT-19570115
  • [Presentation] Structure and function of the N-terminal domains of SUMO ligase Siz/PIAS family2007

    • Author(s)
      Yamazaki T, Suzuki R, Tase A, Nishiuchi Y, Shindo H
    • Organizer
      The 4th International Peptide Symposium
    • Place of Presentation
      Cairns, Australia
    • Year and Date
      2007-10-24
    • Data Source
      KAKENHI-PROJECT-19570115
  • [Presentation] NMR structures and self-sumoylation of the N-terminal SAP domains of SUMO PIAS/Siz family2007

    • Author(s)
      Suzuki R, Shindo H, Tase A, Yamazaki T
    • Organizer
      第47回NMR討論会
    • Place of Presentation
      札幌
    • Year and Date
      2007-09-13
    • Data Source
      KAKENHI-PROJECT-19570115
  • [Presentation] N-terminal SAP and PHD-finger domains of SUMO ligase Siz1 from Oryza sativa are essential for recognition of methylated histone as well as DNA binding2007

    • Author(s)
      Yamazaki T, Suzuki R, Tase A, Nishiuchi Y, Shindo H
    • Organizer
      第47回NMR討論会
    • Place of Presentation
      札幌
    • Year and Date
      2007-09-12
    • Data Source
      KAKENHI-PROJECT-19570115
  • [Presentation] Structure and function of the N-terminal domains of SUMO ligase Siz/PIAS family2007

    • Author(s)
      Yamazaki T, Suzuki R, Tase A, Nishiuchi Y, Shindo H
    • Organizer
      The 4^<th> International Peptide Symposium
    • Place of Presentation
      Cairns,Australia
    • Year and Date
      2007-10-24
    • Data Source
      KAKENHI-PROJECT-19570115
  • [Presentation] Revealing inhibition mechanism against hydroxylamine oxidoreductase (HAO)

    • Author(s)
      Yuki Nishigaya, Toshimasa Yamazaki
    • Organizer
      International BNI workshop 2015
    • Place of Presentation
      Tsukuba
    • Year and Date
      2015-03-02 – 2015-03-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-26310317
  • [Presentation] 構造解析と新規阻害剤を利用したアンモニア酸化細菌由来ヒドロキシルアミン酸化還元酵素に対する硝化抑制剤ターゲットとしてのバリデーション

    • Author(s)
      西ヶ谷有輝、熊谷美穂、土屋渉、藤本瑞、藤原健智、山崎俊正
    • Organizer
      生化学会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-26310317
  • 1.  ISHIDA Yuko (90509861)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 2.  SHINDO Heisaburo (80138966)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 3.  FUJIMOTO Zui (20370679)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 4.  MIYAZAWA Mitsuhiro (90370684)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 5.  SUZUKI Rintaro (00399429)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 6.  ISHIBASHI Jun (20391576)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  MITSUHASHI Wataru (00414946)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KISO Yoshiaki (40089107)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  HAYASHI Yoshio (10322562)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KIMURA Tooru (70204980)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  Awai Koichiro (80431732)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  Konno Kotaro (00355744)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  ONO Hiroshi (90353995)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  MITSUHARA Ichiro (80370683)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  ABE Hiroshi (90360479)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  KAJIWARA Hideyuki (40370647)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  Nishimura Noriyuki (70405041)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  藤原 健智 (80209121)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 19.  平山 隆志 (10228819)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  MATSUMOTO Nobuhiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  YUKUHIRO Fumiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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