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Minami Itsunari  南 一成

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MINAMI Itsunari  南 一成

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Researcher Number 40362537
Other IDs
Affiliation (based on the past Project Information) *help 2019 – 2020: 大阪大学, 医学系研究科, 特任准教授(常勤)
2017: 大阪大学, 医学系研究科, 特任准教授(常勤)
2016 – 2017: 京都大学, 物質-細胞統合システム拠点, 特定拠点助教
2016: 大阪大学, 医学研究科, 特任准教授
2016: 大阪大学, 医学研究科, 特任准教授(常勤) … More
2015: 京都大学, 物質-細胞統合システム拠点, 助教
2015: 京都大学, 物質-細胞統合システム拠点, 助教
2012: 京都大学, 物質-細胞統合システム拠点, 助教
2011: 京都大学, 物質-細胞統合システム拠点, 研究員
2004 – 2005: 京都大学, 医学研究科, 研究員(科学技術振興)(常勤形態) Less
Review Section/Research Field
Principal Investigator
Chemical biology / 睡眠学 / General medical chemistry / Basic Section 90120:Biomaterials-related
Except Principal Investigator
Intelligent mechanics/Mechanical systems / Medium-sized Section 20:Mechanical dynamics, robotics, and related fields / Basic Section 90120:Biomaterials-related
Keywords
Principal Investigator
低分子化合物 / 再生医療 / iPS細胞 / 心筋分化 / ケミカルスクリーニング / 臨床グレード / ヒトES/iPS細胞 / ケミカルバイオロジー / ムスカリニックアセチルコリン受 / 睡眠 … More / 概日リズム / ムスカリニックアセチルコリン受容体 / muscarinic acetylcholine receptor / sleep / circadian rhythm / 心筋分化誘導 / 多能性幹細胞 / 臨床応用 / 心筋細胞 / 細胞凍結法 / 細胞凍結保存 … More
Except Principal Investigator
幹細胞 / ナノファイバー / pluripotent stem cells / cardiomyocytes / maturation / マイクロ加工 / 組織 / 細胞純化 / マイクロ流体デバイス / 細胞分離精製 / 心筋組織化 / 再生医学 / tissue engineering / cardiomyocyte maturation / organ on chip / iPS cell / Cardiomyocyte / Maturation / Traveling wave / pluripotent stem cell / 心筋梗塞治療 / 成熟心筋 / 自発進行波 Less
  • Research Projects

    (9 results)
  • Research Products

    (26 results)
  • Co-Researchers

    (20 People)
  •  組織-臓器凍結保存を目指した生理活性材料のスクリーニングPrincipal Investigator

    • Principal Investigator
      南 一成
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90120:Biomaterials-related
    • Research Institution
      Osaka University
  •  マイクロ・ナノファイバー融合型デバイスを用いた「心神融合」新規培養法の開発

    • Principal Investigator
      藤本 七恵
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 20:Mechanical dynamics, robotics, and related fields
    • Research Institution
      Osaka University
  •  Novel method for treating myocardium infarction by using cardiac tissue ring matured by spontaneous traveling wave

    • Principal Investigator
      李 俊君
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90120:Biomaterials-related
    • Research Institution
      Osaka University
  •  Circulating traveling wave enhances the maturation of cardiomyocytes in self-organized tissue

    • Principal Investigator
      LI Junjun
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Intelligent mechanics/Mechanical systems
    • Research Institution
      Osaka University
  •  Development of the efficient cardiac differentiation method of pluri-poteint stem cells by using novel chemicalsPrincipal Investigator

    • Principal Investigator
      Minami Itsunari
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Osaka University
      Kyoto University
  •  On Chip Purifyication of hiPSC-derived Cells Using a Fishnet-like Mircofluidics

    • Principal Investigator
      Liu Li
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Intelligent mechanics/Mechanical systems
    • Research Institution
      Osaka University
      Kyoto University
  •  安全・配向・成熟心筋移植片の開発

    • Principal Investigator
      陳 勇
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Intelligent mechanics/Mechanical systems
    • Research Institution
      Kyoto University
  •  Discovery and characterization of ES/iPSCs-cardiac differentiation promoting molecules by using chemical screening systemPrincipal Investigator

    • Principal Investigator
      MINAMI Itsunari
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Chemical biology
    • Research Institution
      Kyoto University
  •  Sleep pattern of muscarinic acetylcholine receptors deficient micePrincipal Investigator

    • Principal Investigator
      MINAMI Itsunari
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      睡眠学
    • Research Institution
      Kyoto University

All 2020 2019 2017 2016 2015 2013 2012 2011 2005

All Journal Article Presentation Patent

  • [Journal Article] Circulating re-entrant waves promote maturation of hiPSC-derived cardiomyocytes in self-organized tissue ring2020

    • Author(s)
      Li Junjun、Zhang Lu、Yu Leqian、Minami Itsunari、Miyagawa Shigeru、H?rning Marcel、Dong Ji、Qiao Jing、Qu Xiang、Hua Ying、Fujimoto Nanae、Shiba Yuji、Zhao Yang、Tang Fuchou、Chen Yong、Sawa Yoshiki、Tang Chao、Liu Li
    • Journal Title

      Communications Biology

      Volume: 3

    • DOI

      10.1038/s42003-020-0853-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K12801
  • [Journal Article] Clonal Isolation of Human Pluripotent Stem Cells on Nanofibrous Substrates Reveals an Advanced Sub-clone for Cardiomyocyte Differentiation2019

    • Author(s)
      Yu, L. ; Li, J. ; , Minami, I.; Qu X.; Miyagawa S.; Fujimoto, N.; Hasegawa K.; Chen, Y.; Sawa, Y.; Kotera, H.; Liu, L.,
    • Journal Title

      Advanced Healthcare Materials

      Volume: In press

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K14624
  • [Journal Article] Two dimensional electrophysiological characterization of human pluripotent stem cell-derived cardiomyocyte system.2017

    • Author(s)
      Zhu H, Scharnhorst KS, Stieg AZ, Gimzewski JK, Minami I, Nakatsuji N, Nakano H, Nakano A.
    • Journal Title

      Scientific Reports

      Volume: 7;7 Pages: 43210-43210

    • DOI

      10.1038/srep43210

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08270
  • [Journal Article] Human Pluripotent Stem Cell-Derived Cardiac Tissue-like Constructs for Repairing the Infarcted Myocardium2017

    • Author(s)
      Li Junjun、Minami Itsunari、Shiozaki Motoko、Yu Leqian、Yajima Shin、Miyagawa Shigeru、Shiba Yuji、Morone Nobuhiro、Fukushima Satsuki、Yoshioka Momoko、Li Sisi、Qiao Jing、Li Xin、Wang Lin、Kotera Hidetoshi、Nakatsuji Norio、Sawa Yoshiki、Chen Yong、Liu Li
    • Journal Title

      Stem Cell Reports

      Volume: 9 Pages: 1546-1559

    • DOI

      10.1016/j.stemcr.2017.09.007

    • NAID

      120006358786

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26289065, KAKENHI-PROJECT-15K08270
  • [Journal Article] Impact of extracellular matrix on engraftment and maturation of pluripotent stem cell-derived cardiomyocytes in a rat myocardial infarct model2017

    • Author(s)
      Ogasawara T, Okano S, Ichimura H, Kadota S, Tanaka Y, Minami I, Uesugi M, Wada Y, Saito N, Okada K, Kuwahara K, Shiba Y
    • Journal Title

      Scientific Reports

      Volume: 7 Pages: 8630-8630

    • DOI

      10.1038/s41598-017-09217-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04174, KAKENHI-PROJECT-16K15442, KAKENHI-PROJECT-15K08270
  • [Journal Article] Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis2017

    • Author(s)
      Nakano Haruko、Minami Itsunari、et al.,
    • Journal Title

      eLife

      Volume: 6 Pages: 29330-29330

    • DOI

      10.7554/elife.29330

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08270
  • [Journal Article] Friedreich’s ataxia induced pluripotent stem cell-derived cardiomyocytes display electrophysiological abnormalities and calcium handling deficiency2017

    • Author(s)
      Crombie Duncan E.、Curl Claire L.、Raaijmakers Antonia JA、Sivakumaran Priyadharshini、Kulkarni Tejal、Wong Raymond CB、Minami Itsunari、et al.,
    • Journal Title

      Aging

      Volume: 9 Pages: 1440-1452

    • DOI

      10.18632/aging.101247

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08270
  • [Journal Article] A Synthetic Hybrid Molecule for the Selective Removal of Human Pluripotent Stem Cells from Cell Mixtures.2017

    • Author(s)
      Mao, D., Ando, S., Sato, S., Qin, Y., Hirata, N., Katsuda, Y., Kawase, E., Kuo, T.F., Minami, I., Shiba, Y., Ueda, K., Nakatsuji, N., Uesugi, M.
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 56 Pages: 1765-1770

    • DOI

      10.1002/anie.201610284

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220206, KAKENHI-PROJECT-26440005, KAKENHI-PROJECT-15K17883, KAKENHI-PROJECT-15K08270
  • [Journal Article] Extracellular Recordings of Patterned Human Pluripotent Stem Cell-Derived Cardiomyocytes on Aligned Fibers.2016

    • Author(s)
      Li, J.; Minami, I.; Yu, L.; Tsuji, K.; Nakajima, M.; Qiao, J.; Suzuki, M.; Shimono, K.; Nakatsuji, N.; Kotera, H.; Liu, L*.; Chen, Y*.
    • Journal Title

      Stem Cells Int

      Volume: 2634013 Pages: 2634013-2634013

    • DOI

      10.1155/2016/2634013

    • NAID

      120005829439

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03948, KAKENHI-PROJECT-26289065, KAKENHI-PROJECT-15K08270
  • [Journal Article] Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts2016

    • Author(s)
      Shiba Y, Gomibuchi T, Seto T, Wada Y, Ichimura H, Tanaka Y, Ogasawara T, Okada K, Shiba N, Sakamoto K, Ido D, Shiina T, Ohkura M, Nakai J, Uno N, Kazuki Y, Oshimura M, Minami I, Ikeda U
    • Journal Title

      Natuer

      Volume: 538 Pages: 388-391

    • DOI

      10.1038/nature19815

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01275, KAKENHI-PUBLICLY-16H01378, KAKENHI-PLANNED-16H06502, KAKENHI-PROJECT-26282217, KAKENHI-PROJECT-26461062, KAKENHI-PROJECT-16K14552, KAKENHI-PROJECT-15K08270, KAKENHI-PROJECT-15H05723
  • [Journal Article] On chip purification of hiPSC-derived cardiomyocytes using a fishnet-like microstructure.2016

    • Author(s)
      Xin Li, Leqian Yu, Junjun Li, Itsunari Minami, Minako Nakajima, Yuichiro Noda, Hidetoshi Kotera, Li Liu*, Yong Chen*
    • Journal Title

      Biofabrication

      Volume: 8 Pages: 035017-035017

    • DOI

      10.1088/1758-5090/8/3/035017

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K13911, KAKENHI-PROJECT-15K08270
  • [Journal Article] Development of a reentrant arrhythmia model in human pluripotent stem cell-derived cardiac cell sheets2013

    • Author(s)
      Kadota S, et al.
    • Journal Title

      Eur Heart J.

      Volume: VOL.34 Pages: 1147-1156

    • DOI

      10.1093/eurheartj/ehs418

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J07076, KAKENHI-PROJECT-21340120, KAKENHI-PROJECT-23310087, KAKENHI-PROJECT-23710269
  • [Journal Article] A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine- and xeno-free conditions2012

    • Author(s)
      Minami I, Yamada K, Otsuji TG, Yamamoto T, Shen Y, Otsuka S, Kadota S, Morone N, Barve M, Asai Y, Heuser TT, Heuser JE, Uesugi M, Aiba K, Nakatsuji N
    • Journal Title

      Cell Reports

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23710269
  • [Journal Article] A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine- and xeno-free conditions.2012

    • Author(s)
      Minami I, Yamada K, Otsuji TG, Yamamoto T, Shen Y, Otsuka S, Kadota S, Morone N, Barve M, Asai Y, Tenkova-Heuser T, Heuser JE, Uesugi M, Aiba K, Nakatsuji N
    • Journal Title

      Cell Reports

      Volume: 2(5) Pages: 1448-1460

    • DOI

      10.1016/j.celrep.2012.09.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23310087, KAKENHI-PROJECT-23500446, KAKENHI-PROJECT-23710269, KAKENHI-PROJECT-24790755
  • [Journal Article] Resetting of peripheral circadian clock by prostaglandin E22005

    • Author(s)
      Y Tsuchiya, I Minami, H Kadotani, E Nishida
    • Journal Title

      EMBO Report 6・3

      Pages: 256-261

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16614006
  • [Journal Article] Resetting of peripheral circadian clock by prostaglandin E22005

    • Author(s)
      Y Tsuchiya, I Minami, H Kadotani, E Nishida
    • Journal Title

      EMBO Report 63

      Pages: 256-261

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16614006
  • [Patent] 多能性幹細胞由来心筋細胞の凝集体の凍結方法2017

    • Inventor(s)
      南 一成
    • Industrial Property Rights Holder
      南 一成
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017-03-17
    • Overseas
    • Data Source
      KAKENHI-PROJECT-15K08270
  • [Patent] 組織片2015

    • Inventor(s)
      劉莉、Junjun LI、南一成、陳勇、中辻憲夫
    • Industrial Property Rights Holder
      劉莉、Junjun LI、南一成、陳勇、中辻憲夫
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-10-16
    • Overseas
    • Data Source
      KAKENHI-PROJECT-15H03948
  • [Patent] 多能性幹細胞の心筋分化誘導法2013

    • Inventor(s)
      中辻憲夫、南一成、上杉志成、饗庭一博
    • Industrial Property Rights Holder
      中辻憲夫、南一成、上杉志成、饗庭一博
    • Filing Date
      2013-01-25
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23710269
  • [Patent] 多能性幹細胞の心筋分化促進剤2011

    • Inventor(s)
      中辻憲夫、南一成、上杉志成、山田耕平
    • Industrial Property Rights Holder
      中辻憲夫、南一成、上杉志成、山田耕平
    • Filing Date
      2011-08-24
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23710269
  • [Presentation] iPS-心筋細胞の実用化研究について2017

    • Author(s)
      南一成
    • Organizer
      超異分野学会
    • Place of Presentation
      東京都千代田区外神田
    • Year and Date
      2017-03-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K08270
  • [Presentation] Engineered functional anisotropic and 3-demensional hiPS-derived cardiac tissue-like construct for drug assessment and cardiac disease repairing2016

    • Author(s)
      Li Junjun, Minami Itsunari, Yu, Leqian, Shiba Yuji, Nakatsuji Norio, Liu Li*, Yong Chen*,
    • Organizer
      13th International Society for Stem Cell Research (ISSCR) Annual Meeting
    • Place of Presentation
      San Francisco (USA)
    • Year and Date
      2016-06-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03948
  • [Presentation] iPS細胞由来心筋細胞の応用研究2016

    • Author(s)
      南一成
    • Organizer
      京都市ライフイノベーション創出支援センターシンポジウム
    • Place of Presentation
      京都大学
    • Year and Date
      2016-11-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K08270
  • [Presentation] Human iPSCs-engineered anisotropic cardiac tissue-like construct for drug assessment and cardiac disease repairing.2016

    • Author(s)
      Junjun Li, Liu Li*, Itsunari Minami, Leqian Yu, Motoko Shiozaki, Yuji Shiba, Noburio Morone, Momoko Yoshioka, Sisi Li, Shin Yajima, Satsuki Fukushima, Hitetoshi Kotera, Shigeru Miyagawa, Yoshiki Sawa, Norio Nakatsuji, Yong Chen*
    • Organizer
      Cell Symposia: 10 Years of iPSCs
    • Place of Presentation
      Berkeley (USA)
    • Year and Date
      2016-09-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03948
  • [Presentation] The clinical-grade production of human PSC-derived cardiac cells by using chemical materials2016

    • Author(s)
      南一成
    • Organizer
      信州大学バイオメディカル研究所国際シンポジウム
    • Place of Presentation
      信州大学バイオメディカル研究所
    • Year and Date
      2016-01-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K08270
  • [Presentation] NOVEL SMALL MOLECULES FACILITATE HIGH EFFICIENT CARDIAC DIFFERENTIATION FROM ES AND IPS CELLS2011

    • Author(s)
      Itsunari Minami
    • Organizer
      ISSCR 9th Annual Meeting
    • Place of Presentation
      Canada, Toronto
    • Data Source
      KAKENHI-PROJECT-23710269
  • 1.  Liu Li (50380093)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 2.  LI Junjun (10723786)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 3.  Uesugi Motonari (10402926)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 4.  KOTERA Hidetoshi (20252471)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 5.  陳 勇 (70512458)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 6.  柴 祐司 (70613503)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  藤本 七恵 (00838691)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  MORONE Nobuhiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 9.  HEUSER John
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 10.  OHKURA Masamichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  SATO Shinichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  中辻 憲夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 13.  桑原 宏一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  アグラゼ コンスタンチン
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  椎名 隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  中井 淳一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  池田 宇一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  饗庭 一博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  尾辻 智美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  勝田 陽介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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