Minami Itsunari 南一成

… Alternative Names

Researcher Number	40362537
Other IDs
Affiliation (based on the past Project Information) *help	2019 – 2020: 大阪大学, 医学系研究科, 特任准教授(常勤) 2017: 大阪大学, 医学系研究科, 特任准教授(常勤) 2016 – 2017: 京都大学, 物質－細胞統合システム拠点, 特定拠点助教 2016: 大阪大学, 医学研究科, 特任准教授 2016: 大阪大学, 医学研究科, 特任准教授(常勤) … More
Review Section/Research Field	Principal Investigator Chemical biology / 睡眠学 / General medical chemistry / Basic Section 90120:Biomaterials-related Except Principal Investigator Intelligent mechanics/Mechanical systems / Medium-sized Section 20:Mechanical dynamics, robotics, and related fields / Basic Section 90120:Biomaterials-related
Keywords	Principal Investigator 低分子化合物 / 再生医療 / iPS細胞 / 心筋分化 / ケミカルスクリーニング / 臨床グレード / ヒトES/iPS細胞 / ケミカルバイオロジー / ムスカリニックアセチルコリン受 / 睡眠 … More Except Principal Investigator 幹細胞 / ナノファイバー / pluripotent stem cells / cardiomyocytes / maturation / マイクロ加工 / 組織 / 細胞純化 / マイクロ流体デバイス / 細胞分離精製 / 心筋組織化 / 再生医学 / tissue engineering / cardiomyocyte maturation / organ on chip / iPS cell / Cardiomyocyte / Maturation / Traveling wave / pluripotent stem cell / 心筋梗塞治療 / 成熟心筋 / 自発進行波 Less

組織-臓器凍結保存を目指した生理活性材料のスクリーニングPrincipal Investigator
- Principal Investigator
  
  南一成
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Osaka University
マイクロ・ナノファイバー融合型デバイスを用いた「心神融合」新規培養法の開発
- Principal Investigator
  
  藤本七恵
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 20:Mechanical dynamics, robotics, and related fields
- Research Institution
  Osaka University
Novel method for treating myocardium infarction by using cardiac tissue ring matured by spontaneous traveling wave
- Principal Investigator
  
  李俊君
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Osaka University
Circulating traveling wave enhances the maturation of cardiomyocytes in self-organized tissue
- Principal Investigator
  
  LI Junjun
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Intelligent mechanics/Mechanical systems
- Research Institution
  Osaka University
Development of the efficient cardiac differentiation method of pluri-poteint stem cells by using novel chemicalsPrincipal Investigator
- Principal Investigator
  
  Minami Itsunari
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University
  Kyoto University
On Chip Purifyication of hiPSC-derived Cells Using a Fishnet-like Mircofluidics
- Principal Investigator
  
  Liu Li
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Intelligent mechanics/Mechanical systems
- Research Institution
  Osaka University
  Kyoto University
安全・配向・成熟心筋移植片の開発
- Principal Investigator
  
  陳勇
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Intelligent mechanics/Mechanical systems
- Research Institution
  Kyoto University
Discovery and characterization of ES/iPSCs-cardiac differentiation promoting molecules by using chemical screening systemPrincipal Investigator
- Principal Investigator
  
  MINAMI Itsunari
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical biology
- Research Institution
  Kyoto University
Sleep pattern of muscarinic acetylcholine receptors deficient micePrincipal Investigator
- Principal Investigator
  
  MINAMI Itsunari
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  睡眠学
- Research Institution
  Kyoto University

All 2020 2019 2017 2016 2015 2013 2012 2011 2005

All Journal Article Presentation Patent

[Journal Article] Circulating re-entrant waves promote maturation of hiPSC-derived cardiomyocytes in self-organized tissue ring2020
- Author(s)
  Li Junjun、Zhang Lu、Yu Leqian、Minami Itsunari、Miyagawa Shigeru、H?rning Marcel、Dong Ji、Qiao Jing、Qu Xiang、Hua Ying、Fujimoto Nanae、Shiba Yuji、Zhao Yang、Tang Fuchou、Chen Yong、Sawa Yoshiki、Tang Chao、Liu Li
- Journal Title
  
  Communications Biology
  
  Volume: 3
- DOI
  10.1038/s42003-020-0853-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12801
[Journal Article] Clonal Isolation of Human Pluripotent Stem Cells on Nanofibrous Substrates Reveals an Advanced Sub-clone for Cardiomyocyte Differentiation2019
- Author(s)
  Yu, L. ; Li, J. ; , Minami, I.; Qu X.; Miyagawa S.; Fujimoto, N.; Hasegawa K.; Chen, Y.; Sawa, Y.; Kotera, H.; Liu, L.,
- Journal Title
  
  Advanced Healthcare Materials
  
  Volume: In press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K14624
[Journal Article] Two dimensional electrophysiological characterization of human pluripotent stem cell-derived cardiomyocyte system.2017
- Author(s)
  Zhu H, Scharnhorst KS, Stieg AZ, Gimzewski JK, Minami I, Nakatsuji N, Nakano H, Nakano A.
- Journal Title
  
  Scientific Reports
  
  Volume: 7;7 Pages: 43210-43210
- DOI
  10.1038/srep43210
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08270
[Journal Article] Human Pluripotent Stem Cell-Derived Cardiac Tissue-like Constructs for Repairing the Infarcted Myocardium2017
- Author(s)
  Li Junjun、Minami Itsunari、Shiozaki Motoko、Yu Leqian、Yajima Shin、Miyagawa Shigeru、Shiba Yuji、Morone Nobuhiro、Fukushima Satsuki、Yoshioka Momoko、Li Sisi、Qiao Jing、Li Xin、Wang Lin、Kotera Hidetoshi、Nakatsuji Norio、Sawa Yoshiki、Chen Yong、Liu Li
- Journal Title
  
  Stem Cell Reports
  
  Volume: 9 Pages: 1546-1559
- DOI
  10.1016/j.stemcr.2017.09.007
- NAID
  120006358786
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26289065, KAKENHI-PROJECT-15K08270
[Journal Article] Impact of extracellular matrix on engraftment and maturation of pluripotent stem cell-derived cardiomyocytes in a rat myocardial infarct model2017
- Author(s)
  Ogasawara T, Okano S, Ichimura H, Kadota S, Tanaka Y, Minami I, Uesugi M, Wada Y, Saito N, Okada K, Kuwahara K, Shiba Y
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Pages: 8630-8630
- DOI
  10.1038/s41598-017-09217-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04174, KAKENHI-PROJECT-16K15442, KAKENHI-PROJECT-15K08270
[Journal Article] Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis2017
- Author(s)
  Nakano Haruko、Minami Itsunari、et al.,
- Journal Title
  
  eLife
  
  Volume: 6 Pages: 29330-29330
- DOI
  10.7554/elife.29330
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08270
[Journal Article] Friedreich’s ataxia induced pluripotent stem cell-derived cardiomyocytes display electrophysiological abnormalities and calcium handling deficiency2017
- Author(s)
  Crombie Duncan E.、Curl Claire L.、Raaijmakers Antonia JA、Sivakumaran Priyadharshini、Kulkarni Tejal、Wong Raymond CB、Minami Itsunari、et al.,
- Journal Title
  
  Aging
  
  Volume: 9 Pages: 1440-1452
- DOI
  10.18632/aging.101247
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08270
[Journal Article] A Synthetic Hybrid Molecule for the Selective Removal of Human Pluripotent Stem Cells from Cell Mixtures.2017
- Author(s)
  Mao, D., Ando, S., Sato, S., Qin, Y., Hirata, N., Katsuda, Y., Kawase, E., Kuo, T.F., Minami, I., Shiba, Y., Ueda, K., Nakatsuji, N., Uesugi, M.
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 56 Pages: 1765-1770
- DOI
  10.1002/anie.201610284
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220206, KAKENHI-PROJECT-26440005, KAKENHI-PROJECT-15K17883, KAKENHI-PROJECT-15K08270
[Journal Article] Extracellular Recordings of Patterned Human Pluripotent Stem Cell-Derived Cardiomyocytes on Aligned Fibers.2016
- Author(s)
  Li, J.; Minami, I.; Yu, L.; Tsuji, K.; Nakajima, M.; Qiao, J.; Suzuki, M.; Shimono, K.; Nakatsuji, N.; Kotera, H.; Liu, L*.; Chen, Y*.
- Journal Title
  
  Stem Cells Int
  
  Volume: 2634013 Pages: 2634013-2634013
- DOI
  10.1155/2016/2634013
- NAID
  120005829439
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03948, KAKENHI-PROJECT-26289065, KAKENHI-PROJECT-15K08270
[Journal Article] Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts2016
- Author(s)
  Shiba Y, Gomibuchi T, Seto T, Wada Y, Ichimura H, Tanaka Y, Ogasawara T, Okada K, Shiba N, Sakamoto K, Ido D, Shiina T, Ohkura M, Nakai J, Uno N, Kazuki Y, Oshimura M, Minami I, Ikeda U
- Journal Title
  
  Natuer
  
  Volume: 538 Pages: 388-391
- DOI
  10.1038/nature19815
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01275, KAKENHI-PUBLICLY-16H01378, KAKENHI-PLANNED-16H06502, KAKENHI-PROJECT-26282217, KAKENHI-PROJECT-26461062, KAKENHI-PROJECT-16K14552, KAKENHI-PROJECT-15K08270, KAKENHI-PROJECT-15H05723
[Journal Article] On chip purification of hiPSC-derived cardiomyocytes using a fishnet-like microstructure.2016
- Author(s)
  Xin Li, Leqian Yu, Junjun Li, Itsunari Minami, Minako Nakajima, Yuichiro Noda, Hidetoshi Kotera, Li Liu*, Yong Chen*
- Journal Title
  
  Biofabrication
  
  Volume: 8 Pages: 035017-035017
- DOI
  10.1088/1758-5090/8/3/035017
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K13911, KAKENHI-PROJECT-15K08270
[Journal Article] Development of a reentrant arrhythmia model in human pluripotent stem cell-derived cardiac cell sheets2013
- Author(s)
  Kadota S, et al.
- Journal Title
  
  Eur Heart J.
  
  Volume: VOL.34 Pages: 1147-1156
- DOI
  10.1093/eurheartj/ehs418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J07076, KAKENHI-PROJECT-21340120, KAKENHI-PROJECT-23310087, KAKENHI-PROJECT-23710269
[Journal Article] A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine- and xeno-free conditions2012
- Author(s)
  Minami I, Yamada K, Otsuji TG, Yamamoto T, Shen Y, Otsuka S, Kadota S, Morone N, Barve M, Asai Y, Heuser TT, Heuser JE, Uesugi M, Aiba K, Nakatsuji N
- Journal Title
  
  Cell Reports
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710269
[Journal Article] A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine- and xeno-free conditions.2012
- Author(s)
  Minami I, Yamada K, Otsuji TG, Yamamoto T, Shen Y, Otsuka S, Kadota S, Morone N, Barve M, Asai Y, Tenkova-Heuser T, Heuser JE, Uesugi M, Aiba K, Nakatsuji N
- Journal Title
  
  Cell Reports
  
  Volume: 2(5) Pages: 1448-1460
- DOI
  10.1016/j.celrep.2012.09.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310087, KAKENHI-PROJECT-23500446, KAKENHI-PROJECT-23710269, KAKENHI-PROJECT-24790755
[Journal Article] Resetting of peripheral circadian clock by prostaglandin E22005
- Author(s)
  Y Tsuchiya, I Minami, H Kadotani, E Nishida
- Journal Title
  
  EMBO Report 6・3
  
  Pages: 256-261
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16614006
[Journal Article] Resetting of peripheral circadian clock by prostaglandin E22005
- Author(s)
  Y Tsuchiya, I Minami, H Kadotani, E Nishida
- Journal Title
  
  EMBO Report 63
  
  Pages: 256-261
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16614006
[Patent] 多能性幹細胞由来心筋細胞の凝集体の凍結方法2017
- Inventor(s)
  南　一成
- Industrial Property Rights Holder
  南　一成
- Industrial Property Rights Type
  特許
- Filing Date
  2017-03-17
- Overseas
- Data Source
  KAKENHI-PROJECT-15K08270
[Patent] 組織片2015
- Inventor(s)
  劉莉、Junjun LI、南一成、陳勇、中辻憲夫
- Industrial Property Rights Holder
  劉莉、Junjun LI、南一成、陳勇、中辻憲夫
- Industrial Property Rights Type
  特許
- Filing Date
  2015-10-16
- Overseas
- Data Source
  KAKENHI-PROJECT-15H03948
[Patent] 多能性幹細胞の心筋分化誘導法2013
- Inventor(s)
  中辻憲夫、南一成、上杉志成、饗庭一博
- Industrial Property Rights Holder
  中辻憲夫、南一成、上杉志成、饗庭一博
- Filing Date
  2013-01-25
- Overseas
- Data Source
  KAKENHI-PROJECT-23710269
[Patent] 多能性幹細胞の心筋分化促進剤2011
- Inventor(s)
  中辻憲夫、南一成、上杉志成、山田耕平
- Industrial Property Rights Holder
  中辻憲夫、南一成、上杉志成、山田耕平
- Filing Date
  2011-08-24
- Overseas
- Data Source
  KAKENHI-PROJECT-23710269
[Presentation] iPS-心筋細胞の実用化研究について2017
- Author(s)
  南一成
- Organizer
  超異分野学会
- Place of Presentation
  東京都千代田区外神田
- Year and Date
  2017-03-02
- Invited
- Data Source
  KAKENHI-PROJECT-15K08270
[Presentation] Engineered functional anisotropic and 3-demensional hiPS-derived cardiac tissue-like construct for drug assessment and cardiac disease repairing2016
- Author(s)
  Li Junjun, Minami Itsunari, Yu, Leqian, Shiba Yuji, Nakatsuji Norio, Liu Li*, Yong Chen*,
- Organizer
  13th International Society for Stem Cell Research (ISSCR) Annual Meeting
- Place of Presentation
  San Francisco (USA)
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03948
[Presentation] iPS細胞由来心筋細胞の応用研究2016
- Author(s)
  南一成
- Organizer
  京都市ライフイノベーション創出支援センターシンポジウム
- Place of Presentation
  京都大学
- Year and Date
  2016-11-02
- Invited
- Data Source
  KAKENHI-PROJECT-15K08270
[Presentation] Human iPSCs-engineered anisotropic cardiac tissue-like construct for drug assessment and cardiac disease repairing.2016
- Author(s)
  Junjun Li, Liu Li*, Itsunari Minami, Leqian Yu, Motoko Shiozaki, Yuji Shiba, Noburio Morone, Momoko Yoshioka, Sisi Li, Shin Yajima, Satsuki Fukushima, Hitetoshi Kotera, Shigeru Miyagawa, Yoshiki Sawa, Norio Nakatsuji, Yong Chen*
- Organizer
  Cell Symposia: 10 Years of iPSCs
- Place of Presentation
  Berkeley (USA)
- Year and Date
  2016-09-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03948
[Presentation] The clinical-grade production of human PSC-derived cardiac cells by using chemical materials2016
- Author(s)
  南一成
- Organizer
  信州大学バイオメディカル研究所国際シンポジウム
- Place of Presentation
  信州大学バイオメディカル研究所
- Year and Date
  2016-01-19
- Invited
- Data Source
  KAKENHI-PROJECT-15K08270
[Presentation] NOVEL SMALL MOLECULES FACILITATE HIGH EFFICIENT CARDIAC DIFFERENTIATION FROM ES AND IPS CELLS2011
- Author(s)
  Itsunari Minami
- Organizer
  ISSCR 9th Annual Meeting
- Place of Presentation
  Canada, Toronto
- Data Source
  KAKENHI-PROJECT-23710269

1. Liu Li (50380093)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. LI Junjun (10723786)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. Uesugi Motonari (10402926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. KOTERA Hidetoshi (20252471)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 陳勇 (70512458)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. 柴祐司 (70613503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 藤本七恵 (00838691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MORONE Nobuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. HEUSER John

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. OHKURA Masamichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. SATO Shinichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 中辻憲夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 桑原宏一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. アグラゼコンスタンチン

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 椎名隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 中井淳一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 池田宇一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 饗庭一博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 尾辻智美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 勝田陽介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Minami Itsunari 南 一成

MINAMI Itsunari 南 一成

Research Projects

Research Products

Co-Researchers

組織-臓器凍結保存を目指した生理活性材料のスクリーニングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

マイクロ・ナノファイバー融合型デバイスを用いた「心神融合」新規培養法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel method for treating myocardium infarction by using cardiac tissue ring matured by spontaneous traveling wave

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Circulating traveling wave enhances the maturation of cardiomyocytes in self-organized tissue

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the efficient cardiac differentiation method of pluri-poteint stem cells by using novel chemicalsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

On Chip Purifyication of hiPSC-derived Cells Using a Fishnet-like Mircofluidics

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

安全・配向・成熟心筋移植片の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Discovery and characterization of ES/iPSCs-cardiac differentiation promoting molecules by using chemical screening systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Sleep pattern of muscarinic acetylcholine receptors deficient micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Circulating re-entrant waves promote maturation of hiPSC-derived cardiomyocytes in self-organized tissue ring2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clonal Isolation of Human Pluripotent Stem Cells on Nanofibrous Substrates Reveals an Advanced Sub-clone for Cardiomyocyte Differentiation2019

Author(s)

Journal Title

Data Source

[Journal Article] Two dimensional electrophysiological characterization of human pluripotent stem cell-derived cardiomyocyte system.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human Pluripotent Stem Cell-Derived Cardiac Tissue-like Constructs for Repairing the Infarcted Myocardium2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Impact of extracellular matrix on engraftment and maturation of pluripotent stem cell-derived cardiomyocytes in a rat myocardial infarct model2017

Minami Itsunari 南一成

MINAMI Itsunari 南一成