NAKAI Kozo 中井浩三

Researcher Number	40363204
Other IDs
Affiliation (Current)	2025: 高知大学, 教育研究部医療学系臨床医学部門, 教授
Affiliation (based on the past Project Information) *help	2024: 高知大学, 教育研究部医療学系臨床医学部門, 教授 2016 – 2019: 香川大学, 医学部附属病院, 講師 2015: 香川大学, 医学部, 助教 2011 – 2014: 香川大学, 医学部附属病院, 助教 2013: 香川大学, 医学部, 助教 … More 2010 – 2011: 香川大学, 医学部, 助教 2008 – 2009: 香川大学, 医学部附属病院, 助教 2007 – 2008: Kagawa University, 医学部・附属病院, 助教 2007: 香川大学, 医学部, 助教 2006: 香川大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Dermatology Except Principal Investigator Dermatology / Basic Section 53050:Dermatology-related
Keywords	Principal Investigator 活性酸素 / アトピー性皮膚炎 / マクロファージ細胞 / 自然免疫 / IL-17 / マクロファージ / 国際情報交流 / 国際研究者交流 / フリーラジカル / 治療 … More / 病態 / Klotho / ロリクリン / 酸化ストレス / フィラグリン / 皮膚バリア機能 / アンギオテンシンII / 表皮増殖因子受容体 / 血管内皮細胞増殖因子 / 細胞増殖 / 表皮角化細胞 … More Except Principal Investigator ロリクリン / 免疫チェックポイント阻害分子 / 乾癬 / 単球 / VISTA/PD-1H / 成長因子 / 核酸アナログ / 血管新生 / 結合組織成長因子 / 線維芽細胞 / TGF-β / COA-Cl / 全身性強皮症 / TGF / 強皮症 / コアクロル / CTGF / 線維化 / 皮膚 / GJB2 / コネキシン26 / 臨床薬理学 / 皮膚科学 / 分子遺伝学 / 掌蹠角化症 / 薬物治療学 / フィラグリン / フレーキーテールマウス / バリア / アトピー性皮膚炎 / 魚鱗癬 / ノックアウトマウス / 遺伝性皮膚角化異常症 / バリヤ / 角化 / 角化異常症 / 表皮 / 遺伝子皮膚角化異常症 / 遺伝性皮膚疾患 / シグナル伝達 Less

乾癬単球に発現する免疫チェックポイント分子PD-1H/VISTAは心血管合併症へ寄与するか?
- Principal Investigator
  
  大湖健太郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Kochi University
A novel angigenic agent COA-Cl prohibits fibrotic effect induced by CTGF in human fibroblasts.
- Principal Investigator
  
  KUBOTA YASUO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kagawa University
Clarification of the mechanism and treatment of down-regulated innate immunity in atopic dermatitisPrincipal Investigator
- Principal Investigator
  
  Nakai Kozo
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kagawa University
Study toward the complete therapy of palmoplantar keratoderma
- Principal Investigator
  
  Yoneda Kozo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Osaka Ohtani University
  Kagawa University
Oxidative stress in the skin of a model of atopic dermatitis caused by skin barrier disfunctionPrincipal Investigator
- Principal Investigator
  
  NAKAI Kozo
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Kagawa University
Creation of atopic dermatitis model mouse using double knock out mouse
- Principal Investigator
  
  YONEDA Kozo
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kagawa University
Elucidation of pathophysiology or loricrin keratoderma
- Principal Investigator
  
  YONEDA Kozo
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kagawa University
The effects of reactive oxygen species on proliferation and vascular endothelial growth factor of epidermal keratinocytesPrincipal Investigator
- Principal Investigator
  
  NAKAI Kozo
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Kagawa University

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book

[Book] Filaggrin Jacob P. Thyssen Howard I. Maibach Editors2014
- Author(s)
  Nakai K, Yoneda K, Kubota Y
- Total Pages
  373
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-23791271
[Journal Article] The Effect of Lipopolysaccharide-containing Moisturizing Cream on Skin Care in Patients With Mild Atopic Dermatitis.2019
- Author(s)
  Nakai K, Kubota Y, Soma GI, Kohchi C.
- Journal Title
  
  In Vivo
  
  Volume: 33 Issue: 1 Pages: 109-114
- DOI
  10.21873/invivo.11446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09745
[Journal Article] COA-Cl prevented TGF-β1-induced CTGF expression by Akt dephosphorylation in normal human dermal fibroblasts, and it attenuated skin fibrosis in mice models of systemic sclerosis.2019
- Author(s)
  Nakai K, Karita S, Igarashi J, Tsukamoto I, Hirano K, and Kubota Y
- Journal Title
  
  J Dermatol Sci
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10210
[Journal Article] COA-Cl prevented TGF-β1-induced CTGF expression by Akt dephosphorylation in normal human dermal fibroblasts, and it attenuated skin fibrosis in mice models of systemic sclerosis.2019
- Author(s)
  Nakai K, Karita S, Igarashi J, Tsukamoto I, Hirano K, Kubota Y.
- Journal Title
  
  J Dermatol Sci
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09745
[Journal Article] アトピー性皮膚炎における自然免疫低下2018
- Author(s)
  中井浩三
- Journal Title
  
  月刊　細胞
  
  Volume: 50 Pages: 26-26
- Data Source
  KAKENHI-PROJECT-15K09745
[Journal Article] Localized nodular pemphigoid.2018
- Author(s)
  Yoneda K, Ishii N, Nakai K, Kubota Y and Hashimoto T
- Journal Title
  
  Int J Dermatol
  
  Volume: 57 Issue: 5 Pages: 587-589
- DOI
  10.1111/ijd.13889
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09768, KAKENHI-PROJECT-16K10180
[Journal Article] Macrophages excpress Klotho in skin lesions of psoriatic patients and the skin of imiquimod-treated mice.2018
- Author(s)
  Nakai K, Haba R, Kushida Y, and Kubota Y
- Journal Title
  
  J Dermatol.
  
  Volume: 45 Issue: 12 Pages: 1475-1477
- DOI
  10.1111/1346-8138.14671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09745
[Journal Article] Hypokeratosis of multiple Bowen’s disease of the palms.2017
- Author(s)
  Nakai K, Yoneda K, Moriue J, Moriue T and Kubota Y
- Journal Title
  
  Dermatol Sin
  
  Volume: 35 Issue: 2 Pages: 100-101
- DOI
  10.1016/j.dsi.2016.08.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09768
[Journal Article] IL-17A induces heterogeneous macrophages, and it does not alter the effects of lipopolysaccharides on macrophage activation in the skin of mice.2017
- Author(s)
  Nakai K, He YY, Nishiyama F, Naruse F, Haba R, Kushida Y, Katsuki N, Moriue T, Yoneda K, Kubota Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 29 Issue: 1 Pages: 12473-12473
- DOI
  10.1038/s41598-017-12756-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09745, KAKENHI-PROJECT-15K09768
[Journal Article] Case of a self-inflicted facial ulcer that improved after sepsis2016
- Author(s)
  Nakai K, Yoneda K, Moriue J, Moriue T and Kubota Y
- Journal Title
  
  J Dermatol
  
  Volume: 43 Issue: 5 Pages: 576-577
- DOI
  10.1111/1346-8138.13244
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09768
[Journal Article] betaKlotho expression is reduced in human non-melanoma skin cancer2015
- Author(s)
  Nakai K, Yoneda K, Moriue J, Moriue T, Koura A, Yokoi I, Ishikawa E, Yasuo K, Haba R, Kushida Y, Katsuki N, Inoue S
- Journal Title
  
  International Journal of Dermatology
  
  Volume: 0 Pages: 0-0
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23791271
[Journal Article] Phosphate-buffered saline induces filaggrin expression in a human epidermal keratinocyte cell line (HaCaT cells)2015
- Author(s)
  Nakai K, Yoneda K, Nakagawa T, Moriue T, Kubota Y.
- Journal Title
  
  Dermatologica Sinica
  
  Volume: 0 Pages: 0-0
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23791271
[Journal Article] Effects of topical N-acetylcysteine on skin hydration/transepidermal water loss in healthy volunteers and atopic dermatitis patients2015
- Author(s)
  Kozo Nakai, Kozo Yoneda, Yumi Murakami, Ayako Koura, Reiko Maeda, Asuka Tamai, Emiko Ishikawa, Ikumi Yokoi, Junko Moriue, Tetsuya Moriue, Yasuo Kubota
- Journal Title
  
  Annals of Dermatology
  
  Volume: 0 Pages: 0-0
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23791271
[Journal Article] Multi-branched acquired periungual fibrokeratoma2014
- Author(s)
  Moriue T, Yoneda K, Moriue J, Nakai K and Kubota Y
- Journal Title
  
  JAMA Dermatol
  
  Volume: (Epub ahead of print) Issue: 4 Pages: 456-456
- DOI
  10.1001/jamadermatol.2013.6631
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Detection of apoptotic keratinocytes in a case of bullous pemphigoid developed after graft-versus-host disease2014
- Author(s)
  Yoneda K, Demitsu T, Kakurai M, Narita T, Nakai K, Kubota Y, Ishii N and Hashimoto T
- Journal Title
  
  Acta Derm Venereol
  
  Volume: 94 Pages: 231-232
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Two cases of nevus sebaceous accompanying secondary tumors with βKlotho expression.2014
- Author(s)
  Nakai K, Yoneda K, Haba R, Kushida Y, Katsuki N, Moriue J, Moriue T, Ishikawa E, Inoue S, Kubota Y
- Journal Title
  
  J Dermatol
  
  Volume: 41 Pages: 171-172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791271
[Journal Article] Two cases of nevus sebaceous accompanying secondary tumors with Klothov expression2014
- Author(s)
  Nakai K, Yoneda K, Haba R, Kushida Y, Katsuki N, Moriue J, Moriue T, Ishikawa E, Inoue S and Kubota Y
- Journal Title
  
  J Dermatol
  
  Volume: 41 Issue: 2 Pages: 171-172
- DOI
  10.1111/1346-8138.12371
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] A survey of the factors associated with concerns about oral antihistamine use in Japanese pruritic 30. Hosokawa Y, Yoneda K, Nakai K, Moriue J and Kubota Y: Completely thrombosed venous aneurysm in great saphenous vein2013
- Author(s)
  Moriue J, Yoneda K, Nakai K, Hosokawa Y, Moriue T, and Kubota Y
- Journal Title
  
  Ann Dermatol
  
  Volume: 25 Pages: 268-270
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Successful treatment of primary cutenous anaplastic large cell lymphoma with intralesional methotrexate therapy2013
- Author(s)
  Yokoi I, Ishikawa E, Koura A, Hosokawa Y, Tamai A, Nakai K, Moriue J, Moriue T, Yoneda K and Kubota Y
- Journal Title
  
  Acta Derm Venereol
  
  Volume: (Epub ahead of print) Issue: 3 Pages: 319-320
- DOI
  10.2340/00015555-1692
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Deranged epidermal differentiation in kl/kl mouse and the effects of Klotho siRNA on the differentiation of HaCaT cells2013
- Author(s)
  Nakai K, Yoneda K, Haba R, Kushida Y, Katsuki N, Moriue T, Kosaka H, Kubota Y and Inoue S
- Journal Title
  
  Exp Dermatol
  
  Volume: (Epub ahead of print) Issue: 11 Pages: 772-774
- DOI
  10.1111/exd.12258
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Primary dermal melanoma latent for more than 10 years2013
- Author(s)
  Moriue J, Yoneda K, Moriue T, Nakai K, Katsuki N, Haba R, Ikeda M and Kubota Y
- Journal Title
  
  Ann Dermatol
  
  Volume: 25 Pages: 385-386
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Deranged epidermal differentiation in kl/kl mouse and the effects of βKlotho siRNA on the differentiation of HaCaT cells.2013
- Author(s)
  Nakai K, Yoneda K, Haba R, Kushida Y, Katsuki N, Moriue T, Kosaka H, Kubota Y, Inoue S
- Journal Title
  
  Exp Dermatol
  
  Volume: 22 Pages: 772-774
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791271
[Journal Article] Sphingosine 1-phosphate attenuates peroxide-induced apoptosis in HaCaT cells cultured in vitro2013
- Author(s)
  Moriue T, Igarashi J, Yoneda K, Hashimoto T, Nakai K, Kosaka H and Kubota Y
- Journal Title
  
  Clin Exp Dermatol
  
  Volume: 38 Pages: 638-645
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Primary cutaneous cryptococcosis in a patient with CREST syndrome2012
- Author(s)
  Ishikawa E, Yoneda K, Nakai K, Moriue J, Yokoi I, Munehiro A and Kubota Y
- Journal Title
  
  Eur J Dermatol
  
  Volume: 22 Pages: 421-422
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Reduced expression of epidermal growth factor receptor, E-cadherin, and occludin in the skin of flaky tail mice is due to filaggrin and loricrin deficiencies.2012
- Author(s)
  Nakai K, Yoneda K, Hosokawa Y, Moriue T, Presland RB, Fallon PG, Kabashima K, Kosaka H, Kubota Y.
- Journal Title
  
  American Journal of Pathology
  
  Volume: 181(3) Pages: 969-977
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791271
[Journal Article] Effect of sequential application of topical adapalene and clindamycin phosphate in the treatment of Japanese patients with acne vulgaris2012
- Author(s)
  Kubota Y, Munehiro A, Shirahige Y, Nakai K, Katsuura J, Moriue T, Murakami Y, Matsunaka H and Yoneda K
- Journal Title
  
  J Dermatol Treat
  
  Volume: 23 Pages: 37-45
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Pinch and ligation method: a new non-surgical approach to viral warts2012
- Author(s)
  Moriue T, Yoneda K, Moriue J, Nakai K, Yokoi I, Fujita N, Munehiro A, Maeda R and Kubota Y
- Journal Title
  
  J Dermatol
  
  Volume: 39 Pages: 1108-1109
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Combination effects of cosmetic moisturisers in the topical treatment of acne vulgaris2012
- Author(s)
  Munehiro A, Murakami Y, Shirahige Y, Nakai K, Moriue T, Matsunaka H, Yoneda K and Kubota Y
- Journal Title
  
  J Dermatol Treat
  
  Volume: 23 Pages: 172-176
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Reduced expression of epidermal growth factor receptor, E-cadherin, and occludin in the skin of flaky tail mice is due to filaggrin and loricrin deficiencies2012
- Author(s)
  Nakai K, Yoneda K, Hosokawa Y, Moriue T, Presland RB, Fallon PG, Kabashima K, Kosaka H and Kubota Y
- Journal Title
  
  Am J Pathol
  
  Volume: 181 Pages: 969-977
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Numerous mucin nodules in a patient with seropositive wide spread discoid lupus erythematosus2012
- Author(s)
  Yoneda K, Moriue J, Nakai K, Demitsu T, Moriue T, Yokoi I, Munehiro A, Dobashi H and Kubota Y
- Journal Title
  
  Ann Dermatol
  
  Volume: 24 Pages: 112-114
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Scedosporium apiospermum skin infection mimicking tuberous xanthoma2012
- Author(s)
  Yoneda K, Nakai K, Moriue T, Ishikawa E, Demitsu T, Ohkusu K and Kubota Y
- Journal Title
  
  J Dermatol
  
  Volume: 39 Pages: 316-318
- NAID
  10031184898
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Reduced expression of epidermal growth factor receptor, E-cadherin, and occludin in the skin of flaky tail mice is due to filaggrin and loricrin deficiencies.2012
- Author(s)
  Nakai K
- Journal Title
  
  Am J Pathol
  
  Volume: 181 Issue: 3 Pages: 969-77
- DOI
  10.1016/j.ajpath.2012.06.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Macular lymphocytic arteritis in a patient with rheumatoid arthritis2012
- Author(s)
  Munehiro A, Yoneda K, Koura A, Nakai K and Kubota Y
- Journal Title
  
  Eur J Dermatol
  
  Volume: 22 Pages: 427-42
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Lipid peroxidation-induced VEGF expression in the skin of KKAy obese mice2011
- Author(s)
  Nakai K, Yoneda K, Ishihara Y, Ohmori K, Moriue T, Igarashi J, Kohno M, Kosaka H and Kubota Y
- Journal Title
  
  Exp Dermatol
  
  Volume: 20 Pages: 388-393
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Skin infiltration of pelvic actinomycosis after total gastrectomy2011
- Author(s)
  Yoneda K, Nakai K, Hosokawa Y, Moriue T, Demitsu T and Kubota Y
- Journal Title
  
  Eur J Dermatol
  
  Volume: 21 Pages: 290-291
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Unilateral palm pompholyx in a patient with amyotrophic lateral sclerosis2011
- Author(s)
  Nakai K, Yoneda K, Moriue T, Hosokawa Y, Yokoi I and Kubota Y
- Journal Title
  
  Eur J Dermatol
  
  Volume: 21 Pages: 445-446
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Sarcoidosis presenting transepidermal elimination2011
- Author(s)
  Yoneda K, Kakurai M, Umemoto N, Nakai K, Kubota Y and Demitsu T
- Journal Title
  
  Eur J Dermatol
  
  Volume: 21 Pages: 616-617
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Late radiation dermatitis of the right arm after cardiac catheterization2010
- Author(s)
  Yoneda K, Nakai K, Demitsu T, Moriue T, Moriue J, Yokoi I, Munehiro A, Noma T, Kohno M and Kubota Y
- Journal Title
  
  Eur J Dermatol
  
  Volume: 20 Pages: 654-656
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Bevacizumab-induced hand-foot syndrome: circumscribed type2010
- Author(s)
  Munehiro A, Yoneda K, Nakai K, Demitsu T, Moriue T, Moriue J, Yokoi I, Fujita N, Matsuura N, Ishikawa S, Yokomise H and Kubota Y
- Journal Title
  
  Br J Dermatol
  
  Volume: 162 Pages: 1411-1413
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Seborrhoeic keratoses and acanthosis nigricans in a long-term survivor of thanatophoric dysplasia2010
- Author(s)
  Nakai K, Yoneda K, Moriue T, Munehiro A, Fujita N, Moriue J, Yokoi I, Haba R, Itoh S and Kubota Y
- Journal Title
  
  Br J Dermatol
  
  Volume: 163 Pages: 656-658
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Activation of vascular endothelial growth factor receptor 2 in a cellular model of loricrin keratoderma2010
- Author(s)
  Yoneda K, Demitsu T, Nakai K, Moriue T, Ogawa W, Igarashi J, Kosaka H and Kubota Y
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 16184-16194
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] Community-based epidemiological study of psychosocial effects of acne in Japanese adolescents2010
- Author(s)
  Kubota Y, Shirahige Y, Nakai K, Katsuura J, Moriue T and Yoneda K
- Journal Title
  
  J Dermatol
  
  Volume: 37 Pages: 617-622
- NAID
  10026637291
- Data Source
  KAKENHI-PROJECT-22591240
[Journal Article] HB-EGF-induced VEGF production and eNOS activation depend on both PI3 kinase and MAP kinase in HaCaT cells2009
- Author(s)
  Nakai K
- Journal Title
  
  J Dermatol Sci 55
  
  Pages: 170-178
- NAID
  10029371756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591250
[Journal Article] Narrow-band UVB decreases serum IL-2 receptor levels in patients with piokiloderma vasculare atrophocans2009
- Author(s)
  Nakai K
- Journal Title
  
  J Eur Acad Dermatol Venereol 23
  
  Pages: 844-846
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591250
[Journal Article] Striate palmoplantar keratoderma in patient with Rubinstein-Taybi syndrome2009
- Author(s)
  Nakai K
- Journal Title
  
  J Eur Acad Dermatol Venereol 23
  
  Pages: 333-335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591250
[Journal Article] Subcellular activation site of caspase 3 in apoptotic keratinocytes observed in lichenoid tissue reaction2008
- Author(s)
  Yoneda K, Demitsu T, Matsuoka Y, Moriue T, Nakai K, Kushida Y, Haba R, Kubota Y
- Journal Title
  
  Br J Dermatol 158
  
  Pages: 1166-1168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591250
[Journal Article] Angiotensin II enhances EGF receptor expression levels via ROS formation in HaCaT cells2008
- Author(s)
  Kozo Nakai
- Journal Title
  
  Journal of Dermatological Science 51
  
  Pages: 181-189
- NAID
  10024298430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790791
[Journal Article] Subcellular activation site of caspase 3 in apoptotic keratinocytes observed in lichenoid tissue reaction2008
- Author(s)
  Yoneda K, Demitsu T, Matsuoka Y, Moriue T, Nakai K, Kushida Y, Haba R and Kubota Y
- Journal Title
  
  Br J Dermatol 158
  
  Pages: 1166-1168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591250
[Journal Article] Angiotensin II. enhances EGF receptor expression levels via ROS formation in HaCaT cells2008
- Author(s)
  Kozo Nakai
- Journal Title
  
  Journal of Dermatological Science 51
  
  Pages: 181-189
- NAID
  10024298430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790791
[Journal Article] Angiotensin II enhances EGF receptor expression levels via ROS formation in HaCaT cells2008
- Author(s)
  Kozo Nakai
- Journal Title
  
  Journal of Dermatological Science (In press掲載確定済)
- NAID
  10024298430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790791
[Journal Article] Zosteriform cutaneous metastasis of lung adenocarcinoma
- Author(s)
  Kubota Y, Nakai K, Munehiro A, Moriue J and Yoneda K
- Journal Title
  
  J Clin Exp Dermatol Res
  
  Volume: 36 (in press)
- Data Source
  KAKENHI-PROJECT-22591240
[Presentation] IL-17Aはマウス皮膚のマクロファージ細胞活性化に関与する2018
- Author(s)
  中井浩三、森上徹也、窪田泰夫
- Organizer
  日本アレルギー学会総会
- Data Source
  KAKENHI-PROJECT-15K09745
[Presentation] IL-17A induces heterogeneous macrophages, and it does not alter the effects of lipopolysaccharides on macrophage activation in the skin of mice.2018
- Author(s)
  Kozo Nakai, Yu-Ying He, Reiji Haba, Yoshio Kushida, Naomi Katsuki, Tetsuya Moriue, Kozo Yoneda, and Yasuo Kubota
- Organizer
  IID 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09745
[Presentation] IL-17 is involved in the activation of macrophages in the skin of mouse2017
- Author(s)
  Kozo Nakai, Yu-Ying He, Fumiko Nishiyama, Fukiko Naruse, Tetsuya Moriue, Yasuo Kubota
- Organizer
  Society for Investigative Dermatology 2017 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09745
[Presentation] In vivo evidence of IL-17A induced heterogeneous activation of macrophages in the skin of mouse2017
- Author(s)
  Kozo Nakai, Yu-Ying He, Kozo Yoneda, Tetsuya Moriue, and Yasuo Kubota
- Organizer
  第42回日本研究皮膚科学会総会
- Data Source
  KAKENHI-PROJECT-15K09745
[Presentation] Klotho regulates the differentiation and tumorgenesis of epidermal keratinocytes2012
- Author(s)
  Nakai K, Inoue S, Haba R, Kushida Y, Katsuki N, Hosokawa Y, Moriue T, Yoneda K and Kubota Y
- Organizer
  The 37^<th> Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Okinawa
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PROJECT-22591240
[Presentation] Reduced expression of EGF receptor, E-cadherin and occludin is due to loricrin deficiency in the skin of flaky tail mice2011
- Author(s)
  Nakai K, Yoneda K, Hosokawa Y, Moriue T and Kubota Y
- Organizer
  The 36^<th> Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Kyoto
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-22591240
[Presentation] Direct effects of bevacizumab on cell proliferation and cell signaling pathways in HaCaT cells2011
- Author(s)
  Hosokawa Y, Yoneda K, Moriue T, Nakai K and Kubota Y
- Organizer
  The 36^<th> Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Kyoto
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-22591240
[Presentation] Reduced expression of EGF receptor, E-cadherin and occludin is due to loricrin deficiency in the skin of flaky tail mice2011
- Author(s)
  中井浩三
- Organizer
  日本研究皮膚科学会第３６会年次学術大会・総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23791271
[Presentation] Pitavastatin suppresses lipid peroxidation-induced VEGF expression in the skin of KKAy metabolic syndrome mice2010
- Author(s)
  Nakai K, Yoneda K, Ishihara Y, Ohmori K, Moriue T, Igarashi J, Kohno M, Kosaka H and Kubota Y
- Organizer
  17^<th> Annual Meeting of The Society for Free Radical Biology and Medicine
- Place of Presentation
  Orlando
- Year and Date
  2010-11-18
- Data Source
  KAKENHI-PROJECT-22591240
[Presentation] The effects of oxidized LDL on VEGF production in HaCaT cells: a possible mechanism for psoriasis in metablic syndrome2010
- Author(s)
  Nakai K, Yoneda K, Ishihara Y, Ohmori K, Moriue T, Igarashi J, Kohno M, Kosaka H and Kubota Y
- Organizer
  The 35^<th> Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Wakayama
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-22591240
[Presentation] Abnormally aggregated caveolin-1 in the cytoplasm of cellular model of classic Vohwinkel syndrome2010
- Author(s)
  Yoneda K, Nakai K, Moriue T, Demitsu T and Kubota Y
- Organizer
  The 35^<th> Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Wakayama
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-22591240
[Presentation] Angiotensin II enhances EGF receptor expression in HaCaT cells2008
- Author(s)
  Kozo Nakai
- Organizer
  International Investigative Dermatology 2008
- Place of Presentation
  Kyoto Japan
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-18790791
[Presentation] Angiotensin II enhances EGF receptor expression in HaCaT cells.2008
- Author(s)
  Kozo Nakai
- Organizer
  International Investigative Dermatology 2008
- Place of Presentation
  京都
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-18790791
[Presentation] Angiotensin II enhances EGF receptor expression in. HaCaT cells2008
- Author(s)
  Kozo Nakai
- Organizer
  International Investigative Dermatology 2008
- Place of Presentation
  京都
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-18790791
[Presentation] アンギオテンシンIIはHaCaT細胞の活性酸素産生を増やしてEGF受容体の発現を増加させる2008
- Author(s)
  中井浩三
- Organizer
  第15回四国四大学皮膚科研究会
- Place of Presentation
  高知日本
- Year and Date
  2008-06-21
- Data Source
  KAKENHI-PROJECT-18790791
[Presentation] Angiotensin II enhanced EGF receptor expression in HaCaT cells.2007
- Author(s)
  Kozo Nakai
- Organizer
  SFRBM 14^th annual meeting 2007年
- Place of Presentation
  ワシントンDC USA
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PROJECT-18790791
[Presentation] Angiotensin II enhances EGF receptor expression in HaCaT cells2007
- Author(s)
  Kozo Nakai
- Organizer
  SFRBM 14th annual meeting
- Place of Presentation
  Washington DC USA
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PROJECT-18790791
[Presentation] Free radical production in LPS-treated skin of atopic dermatitis mouse model
- Author(s)
  Kozo Nakai, Maria B Kadiiska, Jin-Jie Jiang, Ronald P. Mason, Tetsuya Moriue, Kozo Yoneda, and Yasuo Kubota
- Organizer
  日本研究皮膚科学会　第39回年次学術大会・総会
- Place of Presentation
  大阪
- Year and Date
  2014-12-12 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-23791271
[Presentation] Reduced expression of EGF receptor, E-cadherin and occludin is due to loricrin deficiency in the skin of flaky tail mice
- Author(s)
  Kozo Nakai, Kozo Yoneda, Yoichiro Hosokawa, Tetsuya Moriue, Yasuo Kubota
- Organizer
  第36回日本研究皮膚科学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23791271
[Presentation] 1. フリーラジカル・酸化ストレス制御によるアレルギー性皮膚疾患治療をめざして
- Author(s)
  中井浩三
- Organizer
  日本皮膚科学会西部支部学術大会
- Place of Presentation
  鹿児島
- Invited
- Data Source
  KAKENHI-PROJECT-23791271
[Presentation] Free radical production in LPS-treated skin of atopic dermatitis mouse model
- Author(s)
  Kozo Nakai, Maria B Kadiiska, Jin-Jie Jiang, Ronald P. Mason, Tetsuya Moriue, Kozo Yoneda, and Yasuo Kubota
- Organizer
  Gordon Research Conference
- Place of Presentation
  Ventura
- Data Source
  KAKENHI-PROJECT-23791271
[Presentation] betaKlotho is required for the epidermal differentiation, and its expression is suppressed in human nonmelanoma skin cancer
- Author(s)
  Kozo Nakai, Shigeaki Inoue, Reiji Haba, Yoshio Kushida, Nahomi Katsuki, Yoichiro Hosokawa, Tetsuya Moriue, Kozo Yoneda and Yasuo Kubota
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Edinbourgh
- Data Source
  KAKENHI-PROJECT-23791271

1. KUBOTA Yasuo (10126047)

# of Collaborated Projects: 4 results

# of Collaborated Products: 38 results
2. YONEDA Kozo (60260626)

# of Collaborated Projects: 3 results

# of Collaborated Products: 37 results
3. ARAKI Nobukazu (10202748)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 塚本郁子 (10183477)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 五十嵐淳介 (20346638)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 大湖健太郎 (90595274)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 中島喜美子 (20403892)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAKAI Kozo 中井 浩三

Research Projects

Research Products

Co-Researchers

乾癬単球に発現する免疫チェックポイント分子PD-1H/VISTAは心血管合併症へ寄与するか?

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A novel angigenic agent COA-Cl prohibits fibrotic effect induced by CTGF in human fibroblasts.

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Clarification of the mechanism and treatment of down-regulated innate immunity in atopic dermatitisPrincipal Investigator

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Study toward the complete therapy of palmoplantar keratoderma

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Oxidative stress in the skin of a model of atopic dermatitis caused by skin barrier disfunctionPrincipal Investigator

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Creation of atopic dermatitis model mouse using double knock out mouse

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Elucidation of pathophysiology or loricrin keratoderma

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The effects of reactive oxygen species on proliferation and vascular endothelial growth factor of epidermal keratinocytesPrincipal Investigator

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[Book] Filaggrin Jacob P. Thyssen Howard I. Maibach Editors2014

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[Journal Article] The Effect of Lipopolysaccharide-containing Moisturizing Cream on Skin Care in Patients With Mild Atopic Dermatitis.2019

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[Journal Article] COA-Cl prevented TGF-β1-induced CTGF expression by Akt dephosphorylation in normal human dermal fibroblasts, and it attenuated skin fibrosis in mice models of systemic sclerosis.2019

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[Journal Article] COA-Cl prevented TGF-β1-induced CTGF expression by Akt dephosphorylation in normal human dermal fibroblasts, and it attenuated skin fibrosis in mice models of systemic sclerosis.2019

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[Journal Article] アトピー性皮膚炎における自然免疫低下2018

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[Journal Article] Localized nodular pemphigoid.2018

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[Journal Article] Macrophages excpress Klotho in skin lesions of psoriatic patients and the skin of imiquimod-treated mice.2018

NAKAI Kozo 中井浩三