Nemoto Takahiro 根本崇宏

… Alternative Names

NEMOTO Takahiro 根本崇宏

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Researcher Number	40366654
Other IDs	https://orcid.org/0000-0002-0100-8763
Affiliation (Current)	2024: 日本医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2017 – 2023: 日本医科大学, 医学部, 准教授 2012 – 2014: 日本医科大学, 医学部, 准教授 2009 – 2011: 日本医科大学, 医学部, 講師 2007 – 2008: Nippon Medical School, 医学部, Assistant Professor 2004 – 2006: 日本医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Embryonic/Neonatal medicine / Basic Section 59040:Nutrition science and health science-related / Obstetrics and gynecology / Psychiatric science Except Principal Investigator Endocrinology / Basic Section 58010:Medical management and medical sociology-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Obstetrics and gynecology
Keywords	Principal Investigator 低出生体重 / グルココルチコイド / 成長ホルモン / 下垂体 / 骨格筋 / 栄養 / 生理学 / エピゲノム / 先制医療 / 成長障害 … More / 低分子RNA / 追いつき成長 / DOHaD / マイクロRNA / ストレス応答 / 低栄養妊娠 / 低出生体重児 / CRF1型受容体 / 短体長低体重 / 出生時低体重児 / HPA軸 / microRNA / ストレス / 低栄養 / カロリー摂取制限 / 低体重児 / 母体 / 発育 / 母胎 / カロリー制限 / GH_3細胞 / 飢餓応答 / 中枢神経細胞死 / 絶食 / オートファジー / 中枢性摂食異常症 / LH, FSH / CRF / 神経性食欲不振症 … More Except Principal Investigator 機械学習 / エネルギー代謝 / グレリン受容体 / グレリン / チューター / Problem Based Learning / 生活習慣病 / 予後 / irisin / myostatin / 発達 / 脳容積 / 栄養管理 / 体組成 / 極低出生体重児 / チュータースキル / 討論議事録 / PBLチューター / 医学教育 / 議事録解析 / PBLチュートリアル / noradrenaline / brown adipose tissue / arcuate nucleus / paraventricular nucleus / vagal nerve / ghrelin receptor / ghrelin / 脂肪代謝 / 視床下部 / 迷走神経節 / ノルアドレナリン / 褐色脂肪組織 / 弓状核 / 視床下部室傍核 / 迷走神経 / 診断ツール / 発現調節 / 病態生理 / ウロコルチン２ / 子宮内膜症 / エクソソーム / マイクロRNA / DNAメチル化 / マイクロDNA / 低栄養 / 追いつき成長 / DNA メチル化 / マイクロ RNA / 成長ホルモン受容体 / 母胎低栄養 / 低出生体重 / 体脂肪 Less

AI advice for effective PBL assignment creation -Development of assignment writing support tools-
- Principal Investigator
  
  早坂明哲
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Nippon Medical School
グルココルチコイド誘導サルコペニア肥満は低出生体重児の疾患発症リスク因子か？Principal Investigator
- Principal Investigator
  
  根本崇宏
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Nippon Medical School
Nutritional management for very low birh weight infants to aimed to normalize body composition and improve neurodevelopmental outcome
- Principal Investigator
  
  中野有也
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Showa University
機械学習で議事録を分析：PBLチュートリアルチューター支援システムの開発
- Principal Investigator
  
  早坂明哲
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Nippon Medical School
Basic research on preemptive medicine for early intervention using the low birth weight modelPrincipal Investigator
- Principal Investigator
  
  Nemoto Takahiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Nippon Medical School
The role of Urocortin2 in the regulatory mechanisms of endometriosis
- Principal Investigator
  
  AKIRA Shigeo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nippon Medical School
The analysis of epigenetic changes in GH-IGF-1 axis of small for gestational age rats
- Principal Investigator
  
  SHIBASAKI Tamotsu
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Endocrinology
- Research Institution
  Nippon Medical School
Pituitary miR-449a modulates CRF type 1 receptor expression and thereby mediates hypothalamic-pituitary-adrenal axis abnormality in offspring from malnourished rat damsPrincipal Investigator
- Principal Investigator
  
  NEMOTO Takahiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Nippon Medical School
Study on energy storage mechanism of ghrelin using transgenic rats whose ghrelin receptor is suppressed
- Principal Investigator
  
  SHIBASAKI TAmotsu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Nippon Medical School
Involvement of intra utero growth retardation on fetal autophagy and infant growthPrincipal Investigator
- Principal Investigator
  
  NEMOTO Takahiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nippon Medical School
Study on the role of ghrelin in the regulatory mechanism of adiposity using transgenic rats whose ghrelin receptor expression is attenuated
- Principal Investigator
  
  SHIBASAKI Tamotsu
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Nippon Medical School
神経性食欲不振症における中枢神経系機能異常への神経細胞オートファジー関与の解明Principal Investigator
- Principal Investigator
  
  根本崇宏
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Nippon Medical School

All 2020 2019 2018 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] Fetal malnutrition-induced catch up failure is caused by elevated levels of miR-322 in rats.2020
- Author(s)
  Nemoto T, Kakinuma Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 10 Issue: 1 Pages: 1339-1339
- DOI
  10.1038/s41598-020-58392-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10195
[Journal Article] Involvement of Noncoding RNAs in Stress-Related Neuropsychiatric Diseases Caused by DOHaD Theory2018
- Author(s)
  Nemoto Takahiro、Kakinuma Yoshihiko
- Journal Title
  
  Adv Exp Med Biol
  
  Volume: 1012 Pages: 49-59
- DOI
  10.1007/978-981-10-5526-3_6
- ISBN
  9789811055256, 9789811055263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10195, KAKENHI-PROJECT-16K08560
[Journal Article] miR-449a contributes to glucocorticoid-induced CRF-R1 downregulation in the pituitary during stress2013
- Author(s)
  Nemoto T, Mano A, Shibasaki T.
- Journal Title
  
  Mol Endocrinol
  
  Volume: 27 Pages: 1593-1602
- Data Source
  KAKENHI-PROJECT-23791238
[Journal Article] Estrogens downregulate urocortin 2 expression in rat uterus.2013
- Author(s)
  Watanabe K, Nemoto T, Akira S, Takeshita T, Shibasaki T.
- Journal Title
  
  Journal of Endocrinology
  
  Volume: 219 Issue: 3 Pages: 269-278
- DOI
  10.1530/joe-13-0228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592490
[Journal Article] miR-449a contributes to glucocorticoid-induced CRF-R1 downregulation in the pituitary during stress2013
- Author(s)
  Nemoto T, Mano A, Shibasaki T
- Journal Title
  
  MOlecular Endocrinology
  
  Volume: 27 Issue: 10 Pages: 1593-1602
- DOI
  10.1210/me.2012-1357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791238
[Journal Article] Genetic suppression of ghrelin receptors activates brown adipocyte function and decreases fat storage in rats.2010
- Author(s)
  Mano-Otagiri A, Iwasaki-Sekino A, Nemoto T, Ohata H, Shibasaki T.
- Journal Title
  
  Regulat Pept 160
  
  Pages: 81-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591103
[Journal Article] Ghrelin suppresses noradrenaline release in the brown a dipose tissue of rats2009
- Author(s)
  A Mano, H Ohata, A Iwasa ki, T Nemoto, T Shibasaki
- Journal Title
  
  Journal of Endocrinology (掲載予定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791173
[Journal Article] Novel action of pituitary urocortin 2 in the regulation of expression and secretion of gonadotropins.2009
- Author(s)
  Takahiro Nemoto, Naoko Yamauchi Tamotsu Shibasaki
- Journal Title
  
  Journal of Endocrinology 201(1)
  
  Pages: 105-114
- Data Source
  KAKENHI-PROJECT-19791173
[Journal Article] Novel action of pituitary urocortin 2 in the regulation of expression and secretion of gonadotropins2009
- Author(s)
  T Nemoto, N Yamauchi, T Shibasaki
- Journal Title
  
  Journal of Endocrinology 201
  
  Pages: 105-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791173
[Journal Article] Regulation of the expression and secretion of urocortin 2 in rat pituitary.2007
- Author(s)
  Nemoto T, Iwasaki-Sekino A, Yamauchi N, Shibasaki T
- Journal Title
  
  Journal of Endocrinology 192 (2)
  
  Pages: 443-452
- Data Source
  KAKENHI-PROJECT-16790703
[Journal Article] Ghrelin suppresses noradrenaline release in the brown adipose tissue of rats
- Author(s)
  Asuka Mano, Hisayuki Ohata, Azusa Iwasaki, Takahiro Nemoto, Tamotsu Shibasaki
- Journal Title
  
  Journal of Endocrinology (in press)
- Data Source
  KAKENHI-PROJECT-19791173
[Presentation] DOHaD学説と神経内分泌2019
- Author(s)
  根本崇宏
- Organizer
  第46回　日本神経内分泌学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10195
[Presentation] Investigation of intervention effect on thrifty phenotype of low birth weight rats2019
- Author(s)
  Takahiro Nemoto
- Organizer
  ENDO2019 (annual meeting of America endocrine society)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10195
[Presentation] Investigation of Intervention Effect on Thrifty Phenotype of Low Birth Weight Rat2019
- Author(s)
  Nemoto T, Kakinuma Y
- Organizer
  ENDO2019（アメリカ内分泌学会2019年年会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10195
[Presentation] 健康体質を規定するホルモンミリュー2019
- Author(s)
  根本崇宏
- Organizer
  日本プロテオーム学会2019年大会・第70回日本電気泳動学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10195
[Presentation] Effects of methyl donor supplementation on embryonic malnutrition-induced low birth weight rats2018
- Author(s)
  Nemoto T, Kakinuma Y
- Organizer
  Nutrition2018（アメリカ栄養学会2018年年会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10195
[Presentation] 低出生体重ラット仔でみられる内分泌学的異常2013
- Author(s)
  根本崇宏、芝﨑　保
- Organizer
  第86回　日本内分泌学会学術総会
- Place of Presentation
  宮城県仙台市
- Invited
- Data Source
  KAKENHI-PROJECT-23791238
[Presentation] 低出生体重ラット仔でみられる内分泌学的異常2013
- Author(s)
  根本崇宏、芝崎保
- Organizer
  第86回日本内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-23659480
[Presentation] 低出生体重ラット仔でみられる内分泌学的異常2013
- Author(s)
  根本崇宏、芝﨑保
- Organizer
  第86回日本内分泌学会総会
- Data Source
  KAKENHI-PROJECT-23791238
[Presentation] 妊娠中に摂取カロリー制限した母ラットより生まれた低出生体重仔の食行動とストレス反応の異常の解析2012
- Author(s)
  根本　崇宏、芝﨑　保
- Organizer
  第16回日本摂食障害学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791238
[Presentation] 低出生体重ラット仔のストレス時のHPA軸反応の異常：下垂体miR-449aのCRF 1型受容体下方制御への関与2012
- Author(s)
  根本　崇宏、芝崎　保
- Organizer
  間脳・下垂体・副腎系研究会（第23回）(招待講演)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791238
[Presentation] miR-449a is involved in glucocorticoid-induced downregulation of CRF type 1 receptor expression2012
- Author(s)
  Nemoto T, Shibasaki T.
- Organizer
  The Endocrine Society 94^<th> Annual Meeting
- Place of Presentation
  Houston, Texas, USA
- Data Source
  KAKENHI-PROJECT-23791238
[Presentation] 低出生体重ラット仔のストレス時のHPA軸反応の異常 : 下垂体miR-449aのCRF 1型受容体下方制御への関与2012
- Author(s)
  根本崇宏,芝﨑保
- Organizer
  第23回間脳・下垂体・副腎系研究会
- Data Source
  KAKENHI-PROJECT-23791238
[Presentation] Pituitary miR-449a is involved in the hypothalamic-pituitary-adrenal axis abnormality in offspring from malnourished dams via CRF type 1 receptor expression modulation2012
- Author(s)
  Nemoto T, Shibasaki T
- Organizer
  19th International Symposium on Regulatory Peptides
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-23791238
[Presentation] 離乳時までに追いつき成長を示さなかった妊娠中のカロリー制限母ラットからの出生仔における成長ホルモン受容体発現低下の機序2012
- Author(s)
  根本崇宏,芝﨑保
- Organizer
  第85回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-23791238
[Presentation] Pituitary miR-449a is involved in the hypothalamic-pituitary-adrenal axis abnormality in offspring from malnourished dams via CRF type 1 receptor expression modulation2012
- Author(s)
  Nemoto T, Shibasaki T.
- Organizer
  International Symposium on regulatory peptide
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-23791238
[Presentation] 離乳時までに追いつき成長を示さなかった妊娠中のカロリー制限母ラットからの出生仔における成長ホルモン受容体発現低下の機序2012
- Author(s)
  根本崇宏、芝﨑　保
- Organizer
  第85回日本内分泌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23659480
[Presentation] miR-449a is involved in glucocorticoid-induced downregulation of CRF type 1 receptor expression.2012
- Author(s)
  Nemoto T, Shibasaki T
- Organizer
  ENDO2012
- Place of Presentation
  Houston, TX, USA
- Data Source
  KAKENHI-PROJECT-23791238
[Presentation] 離乳時までに追いつき成長を示さなかった妊娠中のカロリー制限母ラットからの出生仔における成長ホルモン受容体発現低下の機序2012
- Author(s)
  根本崇宏,芝崎保
- Organizer
  第85回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-23659480
[Presentation] 出生児低体重ラット仔におけるストレスによるHPA軸活性化の異常の解析2011
- Author(s)
  根本　崇宏、芝崎　保
- Organizer
  日本神経内分泌学会（第38回）
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791238
[Presentation] 出生児低体重ラット仔におけるストレスによるHPA軸活性化の異常の解析2011
- Author(s)
  根本崇宏,芝﨑保
- Organizer
  第38回日本神経内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-23791238
[Presentation] Pituitary urocortin 2 is involved in the regulation of expression and secretion of gonadotropins2009
- Author(s)
  Takahiro Nemoto, Naoko Yamauchi, Tamotsu Shibasaki
- Organizer
  The Endocrine Society's Annual Meeting(90th ENDO)
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-19791173
[Presentation] 下垂体ウロコルチン2はゴナドトロピンの遺伝子発現と分泌を抑制している2008
- Author(s)
  根本崇宏、山内直子、芝崎保
- Organizer
  第81回日本内分泌学会
- Place of Presentation
  青森県青森市
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-19791173
[Presentation] 下垂体ウロコルチン2はゴナドトロピンの遺伝子発現と分泌を抑制制御している2008
- Author(s)
  根本崇宏、山内直子、芝崎保
- Organizer
  第81回日本内分泌学会学術総会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-19791173
[Presentation] 「研究成果報告書概要(欧文)」より2007
- Author(s)
  Mano A, Ohata H, Iwasaki A, Nemoto T, Shuto Y, Sugihara H, Oikawa S, Sibasaki T
- Organizer
  80th Japan Endocrine Society Meeting
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-17590969
[Presentation] Roles of ghrelin in the regulatory mechanism of energy metabolism2006
- Author(s)
  Mano A, Ohata H, Iwasaki A, Nemoto T, Shuto Y, Sugihara H, Oikawa S, Shibasaki T
- Organizer
  79th Japan Endocrine
- Place of Presentation
  Kobe
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590969
[Presentation] Actions of ghrelin/growth hormone Secretagogue (GHS) on brown adipose tissue2005
- Author(s)
  Mano A, Sekino A, Nemoto T, Inada S, Shuto Y, Sugihara H, Oikawa S, Shibasaki T
- Organizer
  78th Japan Endocrine Society Meeting
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590969

1. SHIBASAKI TAmotsu (00147399)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
2. MANO Asuka (50343588)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. OHATA Hisayuki (80256924)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 早坂明哲 (50516094)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 藤倉輝道 (00238552)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 藤崎弘士 (60573243)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 三宅弘一 (90267211)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. AKIRA Shigeo (40231849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 井上千鹿子 (90453042)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 中野有也 (40465224)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 高久俊 (50445813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 小田切あすか

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

Nemoto Takahiro 根本 崇宏

NEMOTO Takahiro 根本 崇宏

Research Projects

Research Products

Co-Researchers

AI advice for effective PBL assignment creation -Development of assignment writing support tools-

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

グルココルチコイド誘導サルコペニア肥満は低出生体重児の疾患発症リスク因子か？Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Nutritional management for very low birh weight infants to aimed to normalize body composition and improve neurodevelopmental outcome

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

機械学習で議事録を分析：PBLチュートリアルチューター支援システムの開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basic research on preemptive medicine for early intervention using the low birth weight modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of Urocortin2 in the regulatory mechanisms of endometriosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The analysis of epigenetic changes in GH-IGF-1 axis of small for gestational age rats

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pituitary miR-449a modulates CRF type 1 receptor expression and thereby mediates hypothalamic-pituitary-adrenal axis abnormality in offspring from malnourished rat damsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on energy storage mechanism of ghrelin using transgenic rats whose ghrelin receptor is suppressed

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement of intra utero growth retardation on fetal autophagy and infant growthPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the role of ghrelin in the regulatory mechanism of adiposity using transgenic rats whose ghrelin receptor expression is attenuated

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

神経性食欲不振症における中枢神経系機能異常への神経細胞オートファジー関与の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Fetal malnutrition-induced catch up failure is caused by elevated levels of miR-322 in rats.2020

Author(s)

Journal Title

Nemoto Takahiro 根本崇宏

NEMOTO Takahiro 根本崇宏