KOMAI Norio 駒井則夫

Researcher Number	40368626
Affiliation (based on the past Project Information) *help	2012 – 2013: 川崎医科大学, 医学部, 准教授 2011: 川崎医科大学, 医学部, 講師 2005 – 2008: 川崎医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Kidney internal medicine Except Principal Investigator Kidney internal medicine
Keywords	Principal Investigator 血管透過性 / 糸球体 / 内皮細胞 / 活性酸素種 / 酸化ストレス / 慢性腎臓病 / 一酸化窒素 / 内皮障害 / アルブミン尿 / NO不均衡 … More / ROS / NADPH oxidase / NADPH / NOS / NO / 活性酸素 / 心臓足首血管指数 / 80HDG / NOx / 微量アルブミン尿 / 内皮機能 / アディポネクチン … More Except Principal Investigator 酸化ストレス / 一酸化窒素 / 高血圧 / chronic kidney disease / nitric oxide / oxidative stress / reactive oxygen species / endothelial cell / 糖尿病 / 腎障害 / 進行性腎障害 / 慢性腎臟病 / 内皮細胞障害 / 内皮機能 / 活性酸素 / 糖尿病性腎症 / 内皮機能障害 / 2光子レーザー顕微鏡 / アルブミン尿 / 虚血 / アンジオテンシンII / 慢性腎臓病 / 血管内皮障害 / レニン・アンジオテシン系 / 肥満 / メタボリックシンドローム / 心血管病 / 生活習慣病 / 慢性腎臓病(CKD) Less

Investigation of pathogenesis of albuminuria in chronic kidney disease and its association with cardiovascular complicationsPrincipal Investigator
- Principal Investigator
  
  KOMAI Norio
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kawasaki Medical School
Chronic kidney disease (CKD) as a risk factor for cardiovascular diseases: investigation on pathogenesis and development of therapeutic strategy
- Principal Investigator
  
  KASHIHARA Naoki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kawasaki Medical School
メタボリックシンドロームに関連する腎障害の新しいターゲットの確立Principal Investigator
- Principal Investigator
  
  駒井則夫
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kawasaki Medical School
Implication of reactive oxygen species, nitric oxide, and their imbalance in the pathogenesis of chronic kidney disease
- Principal Investigator
  
  KASHIHARA Naoki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kawasaki Medical School

All 2013 2009 2008 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] Blockade of serotonin 2A receptor improves glomerular endothelial function in rats with streptozotocin-induced diabetic nephropathy2008
- Author(s)
  kobayashi S, Satoh M, Namikoshi T, Haruna Y, Fujimoto S, Arakawa S, Komai N, Tomita N, Sasaki T, Kashihara N
- Journal Title
  
  Clin Exp Nephrol.Clin Exp Nephrol 12
  
  Pages: 119-125
- NAID
  10025352144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590969
[Journal Article] Pioglitazone enhances the antihypertensive and renoprotective effects of candesartan in Zucker obese rats fed a high-protein diet2008
- Author(s)
  Namikoshi T, TomitaN, Satoh M,Haruna Y, Kobayashi S, Komai N,Sasaki T, Kashihara N
- Journal Title
  
  Hypertens Res 31
  
  Pages: 745-755
- NAID
  10021934851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590969
[Journal Article] Pioglitazone enhances the antihypertensive and renoprotective effects of candesartan in Zucker obese rats fed a high-protein diet.2008
- Author(s)
  Namikoshi T, Tomita N, Satoh M, Haruna Y, Kobayashi S, Komai N, Sasaki T, Kashihara N
- Journal Title
  
  Hypertens Res 31
  
  Pages: 745-755
- NAID
  10021934851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590969
[Journal Article] Blockade of serotonin 2A receptor improves glomerular endothelial function in rats with streptozotocin-induced diabetic nephropathy. Clin Exp Nephrol.2008
- Author(s)
  Kobayashi S, Satoh M, Na mikoshi T, Haruna Y, Fujimoto S, Arakawa S, Komai N, Tomita N, Sasaki T, Kashihara N
- Journal Title
  
  Clin Exp Nephrol 12
  
  Pages: 119-125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590969
[Journal Article] Isohumulones Derived from Hops Ameliorate Renal Injury via an Anti-Oxidative Effect in Dahl Salt-Sensitive Rats.2007
- Author(s)
  Tamehachi Namikoshi, Naruya Tomita, Sohachi Fujimoto, Yoshisuke Haruna, Masahito Ohzeki, Norio Komai, Tamaki Sasaki, Aruto Yoshida, Naoki Kashihara
- Journal Title
  
  Hypertens Res 30・2
  
  Pages: 175-84
- NAID
  10018831107
- Data Source
  KAKENHI-PROJECT-17590852
[Journal Article] Endothelial dysfunction in rat adjuvant-induced arthritis : vascular superoxide production by NAD(P)H oxidase and uncoupled endothelial nitric oxide syntase.2006
- Author(s)
  Haruna Y, Morita Y, Komai N, Yada T, Sakuta T, Tomita N, et al
- Journal Title
  
  Arthritis Rheum 54・6
  
  Pages: 1847-55
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590852
[Journal Article] Endothelial dysfunction in rat adjuvant-induced arthritis : vascular superoxide production by NAD(P)H oxidase and uncoupled endothelial nitric oxide synthase.2006
- Author(s)
  Haruna Y, Morita Y, Komai N, Yada T, Sakuta T, Tomita N, Fox DA, Kashihara N
- Journal Title
  
  Arthritis Rheum 54・6
  
  Pages: 1847-55
- Data Source
  KAKENHI-PROJECT-17590852
[Journal Article] Endothelial dysfunction in rat adjuvant-induced arthritis : vascular superoxide production by NAD(P)H oxidase and uncoupled endothelial nitric oxide synthase2006
- Author(s)
  Haruna Y, Morita Y, Komai N, Yada T, Sakuta T, Tomita N, Fox DA, Kashihara N
- Journal Title
  
  Arthritis Rheum 54(6)
  
  Pages: 1847-55
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590852
[Journal Article] NAD(P)H oxidase and uncoupled nitric oxide synthase are major sources of glomerular superoxide in rats with experimental diabetic nephropathy.2005
- Author(s)
  Satoh M, Fujimoto S, Haruna Y, Arakawa S, Horike H, Komai N, Sasaki T, Tsujioka K, Makino H, Kashihara N.
- Journal Title
  
  Am J Physiol Renal Physiol 288・6
- Data Source
  KAKENHI-PROJECT-17590852
[Presentation] Rosuvastatin Maintain Glomerular Endothelial Surface layer Through Nrf2 Activation in Mouse Diabetic Nephropathy2013
- Author(s)
  Ihoriya C, Satoh M, Itano S, Kadoya H, Nishi Y, Kidokoro K, Komai N, Sasaki T, Kashihara N
- Organizer
  ISN World Congress of Nephrology 2013
- Place of Presentation
  Hong Kong Convention and Exhibirion Centre(Hong Kong)
- Year and Date
  2013-06-01
- Data Source
  KAKENHI-PROJECT-23591209
[Presentation] Implication of inflammasome in the development of renal interstitial fibrosis induced by aldsoterone2013
- Author(s)
  Kadoya H, Satoh M, Komai N, Sasaki T, Kashihara N
- Organizer
  The 6^<th> International Aldosterone Forum in Japan
- Place of Presentation
  The Grand Hall(Tokyo)
- Year and Date
  2013-04-21
- Data Source
  KAKENHI-PROJECT-23591209
[Presentation] Implications of Inflammasome-Activation in Macrophage on the Development of Renal Interstitial Inflammation and Fibrosis in Mice2013
- Author(s)
  Kadoya H, Satoh M, Itano S, Ihoriya C, Nishi Y, Kidokoro K, Komai N, Sasaki T, Kashihara N
- Organizer
  ISN World Congress of Nephrology 2013
- Place of Presentation
  Hong Kong Convention and Exhibirion Centre(Hong Kong)
- Year and Date
  2013-06-02
- Data Source
  KAKENHI-PROJECT-23591209
[Presentation] Development of Novel Technique to Visualize in vivo Renin Activity and Analysis of Reno-Protective Actions of Renin Inhibitor in Diabetic Nephropathy2013
- Author(s)
  Kidokoro K, Satoh M, Nishi Y, Ihoriya C, Kadoya H, Komai N, Sasaki T, Kashihara N
- Organizer
  ISN World Congress of Nephrology 2013
- Place of Presentation
  Hong Kong Convention and Exhibirion Centre(Hong Kong)
- Year and Date
  2013-06-01
- Data Source
  KAKENHI-PROJECT-23591209
[Presentation] Uremic Toxins and High Dietary Protein Intake Induce Endothelial Dysfunction in Rats with Chronic Kidney Didease.2009
- Author(s)
  Tamehachi Namikoshi, N aruya Tomita, Minoru Satoh, Takeo Sakuta, Atsunori Kuwabara, Hajime Nagasu, Daisuke Yorimitsu, Norio Komai, Naoki Kashihara
- Organizer
  第73回日本循環器学会総会・学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-03-20
- Data Source
  KAKENHI-PROJECT-19590969
[Presentation] Uremic Toxins and High Dietary Protein Intake Induce Endo thelial Dysfunction in Rats with Chronic Kidney Didease2009
- Author(s)
  Namikoshi T, Tomita N, Satoh M, Kuwabara A, Nagasu H, Yorimitsu D, Komai N,Kashihara N
- Organizer
  第73回日本循環器学会総会・学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-03-20
- Data Source
  KAKENHI-PROJECT-19590969
[Presentation] Implication of inflammasome in the development of renal interstitial fibrosis induced by aldsoterone.
- Author(s)
  Hiroyuki Kadoya, Minoru Satoh, Norio Komai, Tamaki Sasaki,Naoki Kashihara
- Organizer
  The 6th International Aldosterone Forum in Japan
- Place of Presentation
  The Grand Hall(Minato-ku,Tokyo)
- Data Source
  KAKENHI-PROJECT-23591209
[Presentation] Implications of Inflammasome-Activation in Macrophage on the Development of Renal Interstitial Inflammation and Fibrosis in Mice.
- Author(s)
  Kadoya H, Satoh M, Itano S, Ihoriya C, Nishi Y, Kidokoro K, Komai N, Sasaki T, Kashihara N
- Organizer
  ISN World Congress of Nephrology 2013
- Place of Presentation
  Hong Kong Convention and Exhibirion Centre（Hong Kong）
- Data Source
  KAKENHI-PROJECT-23591209

1. KASHIHARA Naoki (10233701)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
2. SATOH Minoru (70449891)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
3. MORITA Yoshitaka (50346441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

KOMAI Norio 駒井 則夫

Research Projects

Research Products

Co-Researchers

Investigation of pathogenesis of albuminuria in chronic kidney disease and its association with cardiovascular complicationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Chronic kidney disease (CKD) as a risk factor for cardiovascular diseases: investigation on pathogenesis and development of therapeutic strategy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

メタボリックシンドロームに関連する腎障害の新しいターゲットの確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Implication of reactive oxygen species, nitric oxide, and their imbalance in the pathogenesis of chronic kidney disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Blockade of serotonin 2A receptor improves glomerular endothelial function in rats with streptozotocin-induced diabetic nephropathy2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Pioglitazone enhances the antihypertensive and renoprotective effects of candesartan in Zucker obese rats fed a high-protein diet2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Pioglitazone enhances the antihypertensive and renoprotective effects of candesartan in Zucker obese rats fed a high-protein diet.2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Blockade of serotonin 2A receptor improves glomerular endothelial function in rats with streptozotocin-induced diabetic nephropathy. Clin Exp Nephrol.2008

Author(s)

Journal Title

Data Source

[Journal Article] Isohumulones Derived from Hops Ameliorate Renal Injury via an Anti-Oxidative Effect in Dahl Salt-Sensitive Rats.2007

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Endothelial dysfunction in rat adjuvant-induced arthritis : vascular superoxide production by NAD(P)H oxidase and uncoupled endothelial nitric oxide syntase.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Endothelial dysfunction in rat adjuvant-induced arthritis : vascular superoxide production by NAD(P)H oxidase and uncoupled endothelial nitric oxide synthase.2006

Author(s)

Journal Title

Data Source

[Journal Article] Endothelial dysfunction in rat adjuvant-induced arthritis : vascular superoxide production by NAD(P)H oxidase and uncoupled endothelial nitric oxide synthase2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] NAD(P)H oxidase and uncoupled nitric oxide synthase are major sources of glomerular superoxide in rats with experimental diabetic nephropathy.2005

Author(s)

Journal Title

Data Source

[Presentation] Rosuvastatin Maintain Glomerular Endothelial Surface layer Through Nrf2 Activation in Mouse Diabetic Nephropathy2013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Implication of inflammasome in the development of renal interstitial fibrosis induced by aldsoterone2013

Author(s)

Organizer

Place of Presentation

KOMAI Norio 駒井則夫