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Horishita Takafumi  堀下 貴文

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HORISHITA Takafumi  堀下 貴文

HORISHITA Takahumi  堀下 貴文

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Researcher Number 40369070
Affiliation (Current) 2025: 産業医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2020 – 2024: 産業医科大学, 医学部, 教授
2015 – 2019: 産業医科大学, 医学部, 准教授
2009 – 2014: University of Occupational and Environmental Health, Japan, 医学部, 講師
2006: 産業医大, 医学部, 助手
2003 – 2005: 産業医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Basic Section 55050:Anesthesiology-related / Anesthesiology/Resuscitation studies / Anesthesiology
Except Principal Investigator
Anesthesiology/Resuscitation studies / Basic Section 55050:Anesthesiology-related / Anesthesiology/Resuscitation studies / Anesthesiology
Keywords
Principal Investigator
新たな鎮痛薬開発 / 慢性疼痛 / 先天性無痛症 / 電位依存性ナトリウムチャネル / 神経障害性疼痛 / 内因性カンナビノイド / アロプレグナノロン / アフリカツメガエル卵母細胞発現系 / ニューロステロイド / 電気生理学的解析 … More / 機能獲得型Nav1.9 / 新規鎮痛薬・鎮痛法の開発 / 病態機序解明 / Nav1.7機能喪失 / Nav1.7と痛み受容体の相互関係 / 先天性無痛症の病態解明 / 局所麻酔作用 / 機能喪失型Nav1.7 / 選択的Nav1.9阻害薬 / Nav1.9抑制機序 / 新たな鎮痛薬 / Nav1.9 / 抗うつ薬 / TRPA1受容体 / TRPM8受容体 / 温度感受性受容体 / 冷感アロディニア / 疼痛抑制機序の解明 / アナンダマイド / 疼痛機構 / PS / 麻酔作用 / ニユーロステロイド / プレグナノロン / 作用機序 / 疼痛機序 / 鎮痛作用 / ニューステロイド / ナトリウムチャネル / 疼痛管理学 / 細胞内カルシウム上昇抑制 / サブスタンスP受容体 / Gタンパク結合受容体 / 細胞内カルシウム濃度測定 / ラット培養DRG細胞 / 脊髄 / 抗侵害作用 / プレグネノロン / Na_v1.4 / Na_v1.2 / Naチャネル … More
Except Principal Investigator
アフリカツメガエル卵母細胞発現系 / 麻酔薬 / 神経障害性疼痛 / 慢性疼痛 / Anesthetics / Xenopus oocyte / Protein Kinase C (PKC) / ハロセン / エンフルラン / イソフルラン / 鎮痛薬 / 新たな鎮痛薬開発 / 細胞内リン酸化酵素 / 電気生理学的解析 / ASIC機能抑制機序 / 酸感受性イオンチャネル(ASIC) / 新規鎮痛薬開発 / α9AChRの抑制機序解明 / α9AChR / ニコチン性アセチルコリン受容体(nAChR) / アフリカツメガエル卵母細胞 / 脊椎後根神経節細胞 / オピオイド / ナトリウム チャンネル / 培養脊髄後根神経節細胞 / TRP / 培養脊椎後根神経節細胞 / アフリカツメガエル卵母細胞発現 / G蛋白共役型受容体 / オピドイド受容体 / 電位依存性Na+チャネル / ロピバカイン / メピバカイン / リドカイン / TRPV3 / オピオイド受容体 / 電位依存性Naチャネル(Nav) / カルバクロール / バニロイド受容体サブタイプ3 / オピオイド受容体(OR) / Nav1.7 / 局所麻酔薬 / Phosphorylation / Dexmedetomidine / Xenopus oocytes expression systems / Metabotropic glutamte receptors / Dorsal root ganglia cells / G protein couples receptors / Pain mechanism / メタボトロピックグルタミン酸受容体(cGluR) / 脊髄後根神経節(Dorsal Root Gnglia, DRG)細胞 / 脊髄後根神経節(DRG)細胞 / G蛋白結合受容体(GPCR) / デクスメデトミジン / アフリカツメガエル卵母細胞系 / メタボトロピックグルタミン酸受容体(mGluR) / 脊髄後根神経節(Dorsal Root Ganglia, DRG)細胞 / G蛋白共役型受容体(GPCR) / 疼痛メカニズム / orexin A / Tramadol / substance P / G-protein coupled receptor (GPCR) / ion channels / dorsal root ganglia cells / G蛋白結合受容体 / イオンチャンネル / 疼痛発生メカニズム / エーテル / 静脈麻酔薬 / ステロイド系静脈麻酔薬アルファキサロン / 電位依存性Naチャネル / オレキシンA / トラマドール / サブスタンスP / G蛋白共役型受容体 / イオンチャネル / 脊髄後根神経節 / 吸入麻酔薬 / Halothane / Enflurane / Isoflurane / Protein G / Cannabinoid Receptor / Gq蛋白 / Gi / Ca^<2+>依存性Cl^-チャネル / G蛋白質共役型受容体 / Protein Kinase C(PKC) / G蛋白 / カナビノイド受容体 / Nav1.3選択的阻害薬 / Nav1.3サブユニット / 電位依存性ナトリウムチャネル / P2X受容体 / 全身麻酔薬 / 癌性疼痛 / P2X_7受容体 / P2X_4受容体 / 疼痛発現機構 / サブユニット選択的作用 / P2X7受容体 / ATP受容体 / 疹痛管理学 / ^3H-thymidine / 静脈性麻酔ケタミン / 動脈平滑筋 / 生活習慣病 / 動脈硬化 / 血管障害性動脈硬化 / [^3H]-thymidine / 細胞内cAMP / 静脈性麻酔薬ケタミン / 血管平滑筋増殖 / Alphaxalone / 副腎髄質細胞 / ニコチン受容体 / ムスカリン受容体 / ニューロステロイド Less
  • Research Projects

    (17 results)
  • Research Products

    (36 results)
  • Co-Researchers

    (15 People)
  •  難治性慢性疼痛に対する選択的ASIC阻害薬開発を目指したASIC抑制機構の解明

    • Principal Investigator
      濱田 高太郎
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  新規鎮痛薬開発を目指した、機能獲得型Nav1.9による先天性無痛症の病態解明Principal Investigator

    • Principal Investigator
      堀下 貴文
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  難治性慢性疼痛に対する新規鎮痛薬開発を目指したα9 nACh受容体抑制機序の解明

    • Principal Investigator
      緒方 裕一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Elucidation of pathological mechanism of congenital insensitivity to pain with loss of Nav1.7 function for the development of new analgesics and analgesic methodsPrincipal Investigator

    • Principal Investigator
      Horishita Takafumi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Functional analysis of voltage-gated sodium channel in anesthesia mechanism using dorsal root ganglion cells

    • Principal Investigator
      MINAMI KOUICHIRO
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Jichi Medical University
  •  Investigation of the mechanisms of Nav1.9 inhibition aimed at development of selective Nav1.9 inhibitor for chronic painPrincipal Investigator

    • Principal Investigator
      Horishita Takafumi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Elucidation of the mechanisms underlying inhibition of TRPM8 receptor aimed at development of novel analgesics to treat cold allodyniaPrincipal Investigator

    • Principal Investigator
      HORISHITA Takafumi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Analysis of the mechanisms underlying inhibition of voltage-gated sodium channel aimed at development of selective inhibitor on Nav1.3

    • Principal Investigator
      SATA Takeyoshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Analysis of the mechanisms of pain relief by endocannabinoids aimed at development of analgesics for neuropathic painPrincipal Investigator

    • Principal Investigator
      HORISHITA Takafumi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Investigations of painmechanism related to ATP receptors aiming at new analgesics for cancer pain

    • Principal Investigator
      SATA Takeyoshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Analysis of the action mechanisms of volatile anesthetics and analgesics aimed at development of selective sodium channel blockerPrincipal Investigator

    • Principal Investigator
      HORISHITA Takafumi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  The role of the metabotropic gultamete receptor in the pain mechanism

    • Principal Investigator
      SHIGA Yousuke
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  麻酔薬の動脈硬化予防作用の臨床応用を目指した研究-麻酔薬の新たなる作用の検討-

    • Principal Investigator
      SHIGEMATSU Akio
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  ニューロステロイドの鎮痛機序解明を目指した中枢-脊髄-末梢神経での総合的解析Principal Investigator

    • Principal Investigator
      堀下 貴文
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  The study of antinociceptive effects of anesthetics and analgesics using dorsal root ganglia cells.

    • Principal Investigator
      SHIGEMATSU Akio
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational Environmental Health(UOEH)
  •  ニューロステロイドのG蛋白結合受容体及びリガンド結合イオンチャンネルに及ぼす影響

    • Principal Investigator
      MINAMI Kouitiro
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  The effects of anesthetics and ethanol on cannabinoid receptor function.

    • Principal Investigator
      KAMOCHI Masayuki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan

All 2021 2020 2019 2017 2015 2014 2013 2012 2011 2010 2007 2005 2002 Other

All Journal Article Presentation Book

  • [Book] Basic and Systemic Mechanisms of Anesthesia (Volatile anesthetics, enflurane, isoflurane inhibit 5-hydroxytryptamine type 2C receptors expressed in Xenopus oocytes. pp277-278)2005

    • Author(s)
      Horishita T., et al.
    • Publisher
      ELSEVIER
    • Data Source
      KAKENHI-PROJECT-17591657
  • [Book] Basic an dSystemic Mechanisms of Anesthesia8Bolatile anesthetics, enflurane, isoflurane inhibit 5-hydroxytryptamine type 2C receptors expressed in Xenopus oocytes.pp277-278)2005

    • Author(s)
      Horishita T., et al.
    • Publisher
      ELSEVIER
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390479
  • [Book] Basic and Systemic Mechanisms of Anesthesia (Volatile anesthetics, enflurane, isoflurane inhibit 5-hydroxytryptamine type 2C receptors expressed in Xenopus oocytes.2005

    • Author(s)
      Horishita T., et al.
    • Total Pages
      342
    • Publisher
      ELSEVIER
    • Data Source
      KAKENHI-PROJECT-16659429
  • [Book] Basic and Systemic Mechanisms of Anesthesia (Volatile anesthetics, enflurane, isoflurane inhibit 5-hydroxytryptamine type 2C receptors expressed in Xenopus oocytes, pp277-278)2005

    • Author(s)
      Horishita T., et al.
    • Total Pages
      342
    • Publisher
      ELSEVIER
    • Data Source
      KAKENHI-PROJECT-16790905
  • [Book] Basic and Systemic Mechanisms of Anesthesia (Volatile anesthetics, enflurane, isoflurane inhibit 5-hydroxytryptamine type 2C receptors expressed in Xenopus oocytes. pp277-278)2005

    • Author(s)
      Horishita T., et al.
    • Publisher
      ELSEVIER
    • Data Source
      KAKENHI-PROJECT-15390479
  • [Journal Article] Local Anesthetics Inhibit Transient Receptor Potential Vanilloid Subtype 3 Channel Function in Xenopus Oocytes2021

    • Author(s)
      Reiko Horishita, Yuichi Ogata, Ryo Fukui, Ryo Yamazaki, Kuniaki Moriwaki, Susumu Ueno, Nobuyuki Yanagihara, Yasuhito Uezono, Yuka Yokoyama, Kouichiro Minami, Takafumi Horishita
    • Journal Title

      Anesth Analg

      Volume: 1756-1767 Issue: 6 Pages: 1756-1767

    • DOI

      10.1213/ane.0000000000005546

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09382, KAKENHI-PROJECT-21K06584
  • [Journal Article] Carvacrol inhibits the neuronal voltage-gated sodium channels Nav1.2, Nav1.6, Nav1.3, Nav1.7, and Nav1.8 expressed in Xenopus oocytes with different potencies2020

    • Author(s)
      Horishita Takafumi、Ogata Yuichi、Horishita Reiko、Fukui Ryo、Moriwaki Kuniaki、Ueno Susumu、Yanagihara Nobuyuki、Uezono Yasuhito、Sudo Yuka、Minami Kouichiro
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 142 Issue: 4 Pages: 140-147

    • DOI

      10.1016/j.jphs.2019.12.009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09382, KAKENHI-PROJECT-18K07404
  • [Journal Article] The endocannabinoid anandamide inhibits voltage-gated sodium channels NaV1.2, NaV1.6, NaV1.7 and NaV1.8 in Xenopus Oocytes.2014

    • Author(s)
      Okura D, Horishita T, Ueno S, Yanagihara N, Sudo Y, Uezono Y, Sata T.
    • Journal Title

      Anesth Analg

      Volume: 118 Issue: 3 Pages: 554-562

    • DOI

      10.1213/ane.0000000000000070

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590740, KAKENHI-PROJECT-24592369, KAKENHI-PROJECT-25860200
  • [Journal Article] Effects of anesthetics on the function of orexiir 1 receptors expressed in Xen op us oocytes.2007

    • Author(s)
      Minami K, Uezono Y, Sakurai T, Horishita T, Shiraishi M, Ueta Y.
    • Journal Title

      Pharmacology. 79(4)

      Pages: 236-42

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591657
  • [Journal Article] Dexmedetomidine inhibits muscarinic type 3 receptors expressed in Xenop us oocytes and muscarine induced intracellular Ca^<2+> elevation in cultured rat dorsal root ganglia cells.2007

    • Author(s)
      Takizuka A, Minami K, Uezono Y, Horishita T, Yokoyama T, Shiraishi M, Sakurai T, Shigematsu A, Ueta Y.
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol. 375(5)

      Pages: 293-301

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591657
  • [Journal Article] The effects of the neurosteroids : Progesterone and Dehydroepiandrosterone on muscarinic receptor-induced responses in Xenopus oocytes expressing M_1 and M_3 receptors.2005

    • Author(s)
      Horishita T., et al.
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacil 371・3

      Pages: 221-228

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390479
  • [Journal Article] The effects of the neurosteroids : Pregnenolone, Progesterone and Dehydroepiandrosterone on muscarinic receptor-induced responses in Xenopus oocytes expressing M_1 and M_3 receptors.2005

    • Author(s)
      Horishita T., et al.
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol 371・3

      Pages: 221-228

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390479
  • [Journal Article] Alphaxalone, a neurosteroid anesthetic, inhibits norepinephrine transporter function in cultured bovine adrenal medullary cells.2002

    • Author(s)
      Horishita T., et al.
    • Journal Title

      Anesth Analg 95・6

      Pages: 1661-1666

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571479
  • [Journal Article] The Tramadol Metabolite, O-desmethyl Tramadol, Inhibits 5-Hydroxytryptamine Type 2C Recrptors Expressed in Xenopus Oocytes.

    • Author(s)
      Horishita T., et al.
    • Journal Title

      Pharmacology (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390479
  • [Journal Article] The effects of the neurosteroids : Pregnenolone, Progesterone and Dehydroepiandrosterone on muscarinic receptor-induced responses in Xenopus oocytes expressing M1 and M3 receptors.

    • Author(s)
      Horishita T., et al.
    • Journal Title

      Naunyn-Schmiedeberg's Archives of Pharmacology (In press)

    • Data Source
      KAKENHI-PROJECT-16790905
  • [Journal Article] The effects of the neurosteroids : Pregnenolone, Progesterone and Dehydroepiandrosterone on muscarinic receptor-induced responses in Xenopus oocytes expressing M1 and M3 receptors.

    • Author(s)
      Horishita T., et al.
    • Journal Title

      Naunyn-Schmiedeberg's Archives of Pharmacology (In press)

    • Data Source
      KAKENHI-PROJECT-15390479
  • [Journal Article] The Tramadol Metabolite, O-desmethyl Tramadol, Inhibits 5-Hydroxytryptamine Type 2C Receptors Expressed in Xenopus Oocytes

    • Author(s)
      Horishita T., et al.
    • Journal Title

      Pharmacology (In press)

    • Data Source
      KAKENHI-PROJECT-15390479
  • [Journal Article] The effects of the neurosteroids : Pregnenolone, Progesterone and Dehydroepiandrosterone on muscarinic receptor-induced responses in Xenopus oocytes expressing M1 and M3 receptors.

    • Author(s)
      Horishita T., et al.
    • Journal Title

      Naunyn-Schmiedeberg's Archives of Pharmacology (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571479
  • [Journal Article] The Tramadol Metabolite, 0-desmethyl Tramadol, Inhibits 5-Hydroxytryptamine Type 2C Receptors Expressed in Xenopus Oocytes

    • Author(s)
      Horishita T., et al.
    • Journal Title

      Pharmacology (In press)

    • Data Source
      KAKENHI-PROJECT-16790905
  • [Journal Article] The Tramadol Metabolite, 0-desmethyl Tramadol, Inhibits 5-Hydroxytryptamine Type 2C Receptors Expressed in Xenopus Oocytes

    • Author(s)
      Horishita T., et al.
    • Journal Title

      Pharmacology (In press)

    • Data Source
      KAKENHI-PROJECT-16659429
  • [Journal Article] The effects of the neurosteroids : Pregnenolone, Progesterone and Dehydroepiandrosterone on muscarinic receptor-induced responses in Xenopus oocytes expressing M_1 and M_3 receptors

    • Author(s)
      Horishita T., et al.
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571479
  • [Journal Article] The effects of the neurosteroids : Pregnenolone, Progesterone and Dehydroepiandrosterone on muscarinic receptor-induced responses in Xenopus oocytes expressing M1 and M3 receptors.

    • Author(s)
      Horishita T., et al.
    • Journal Title

      Naunyn-Schmiedeberg's Archives of Pharmacology In press

    • Data Source
      KAKENHI-PROJECT-14571479
  • [Journal Article] The Tramadol Metabolite, O-desmethyl Tramadol, Inhibits 5-Hydroxytryptamine Type 2C Receptors Expressed in Xenopus Oocytes

    • Author(s)
      Horishita T., et al.
    • Journal Title

      Pharmacology (In press)

    • Data Source
      KAKENHI-PROJECT-17591657
  • [Journal Article] The Tramadol Metabolite, O-desmethyl Tramadol, Inhibits 5-Hydroxytryptamine Type 2C Receptors Expressed in Xenopus Oocytes.

    • Author(s)
      Horishita T., et al.
    • Journal Title

      Pharmacology (In press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390479
  • [Presentation] 止痢薬ロペラミドは温度感受性TRPチャネルファミリー,TRPM8機能を抑制する2020

    • Author(s)
      福井遼,緒方裕一,森脇邦明,堀下玲子,堀下貴文
    • Organizer
      日本麻酔科学会第67回学術集会
    • Data Source
      KAKENHI-PROJECT-19K09382
  • [Presentation] クロルプロマジンは電位依存性ナトリウムチャネルαサブユニット、Nav1.2、Nav1.3、Nav1.6、Nav1.7、Nav1.8機能を抑制する2019

    • Author(s)
      堀下貴文、堀下玲子、南智子、緒方裕一、川﨑貴士
    • Organizer
      日本麻酔科学会第66回学術集会
    • Data Source
      KAKENHI-PROJECT-18K08876
  • [Presentation] Lidocaine inhibits 2APB-induced currents of TRPV3 channels expressed in Xenopus oocytes2017

    • Author(s)
      Reiko Horishita, Takafumi Horishita, Dan Okura, Tomoko Minami, Yuichi Ogata, Takashi Kawasaki
    • Organizer
      2017 Annual meeting, American Society of Anesthesiologists
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10567
  • [Presentation] カルバクロールは、電位依存性ナトリウムチャネルαサブユニット、Nav1.2、Nav1.3、Nav1.6、Nav1.7、Nav1.8機能を抑制する2015

    • Author(s)
      堀下貴文、大倉暖、土山玲子、南智子、熊倉美佳、佐多竹良
    • Organizer
      日本麻酔科学会第62回学術集会
    • Place of Presentation
      神戸ポートピアホテル(兵庫県神戸市)
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-25462462
  • [Presentation] 温度感受性TRPチャネルサブファミリー、TRPA1に対するガバペンチンの影響2015

    • Author(s)
      土山玲子、堀下貴文、大倉暖、南智子、佐多竹良
    • Organizer
      日本麻酔科学会第62回学術集会
    • Place of Presentation
      神戸国際展示場(兵庫県神戸市)
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-15K10567
  • [Presentation] リドカインはATP受容体サブタイプ、P2×_7受容体機能を抑制する2013

    • Author(s)
      大倉暖、堀下貴文、佐多竹良
    • Organizer
      日本麻酔科学会第60回学術集会
    • Place of Presentation
      札幌(ロイトン札幌)
    • Year and Date
      2013-05-23
    • Data Source
      KAKENHI-PROJECT-22591756
  • [Presentation] 電位依存性ナトリウムチャネルサブユニット、Nav1.3に対する抗うつ薬の影響2013

    • Author(s)
      堀下貴文
    • Organizer
      日本麻酔科学会第60回学術集会
    • Place of Presentation
      ロイトン札幌
    • Data Source
      KAKENHI-PROJECT-25462462
  • [Presentation] 抗うつ薬の電位依存性ナトリウムチャネルに対する影響2012

    • Author(s)
      堀下貴文
    • Organizer
      日本麻酔科学会第59回学術集会
    • Place of Presentation
      神戸市(神戸ポートピアホテル)
    • Data Source
      KAKENHI-PROJECT-24592369
  • [Presentation] 内因性カンナビノイド、アナンダマイドの電位依存性ナトリウムチャネルに対する影響2011

    • Author(s)
      堀下貴文
    • Organizer
      日本麻酔科学会第58回学術集会
    • Place of Presentation
      神戸国際展示場(神戸)
    • Year and Date
      2011-05-20
    • Data Source
      KAKENHI-PROJECT-21791480
  • [Presentation] 内因性カンナビノイド、アナンダマイドの電位依存性ナトリウムチャネルに対する影響2011

    • Author(s)
      堀下貴文
    • Organizer
      日本麻酔科学会第58回学術集会
    • Place of Presentation
      神戸国際会議場(神戸)
    • Year and Date
      2011-05-20
    • Data Source
      KAKENHI-PROJECT-21791480
  • [Presentation] ニューロステロイドの電位依存性ナトリウムチャネルNav1.2機能に対する影響2010

    • Author(s)
      堀下貴文
    • Organizer
      日本麻酔科学会第57回学術集会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Year and Date
      2010-06-03
    • Data Source
      KAKENHI-PROJECT-21791480
  • [Presentation] ニューロステロイドの電位依存性ナトリウムチャネルNa_v1.2機能に対する影響2010

    • Author(s)
      堀下貴文、佐多竹良
    • Organizer
      日本麻酔科学会第57回学術集会
    • Place of Presentation
      福岡(福岡国際会議場)
    • Year and Date
      2010-06-03
    • Data Source
      KAKENHI-PROJECT-21791480
  • 1.  MINAMI Kouitiro (70279347)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 4 results
  • 2.  OOKURA Dan (00596710)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 4 results
  • 3.  UEZONO Yasuhito (20213340)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 3 results
  • 4.  SATA Takeyoshi (60128030)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 3 results
  • 5.  SHIRAISHI Munehiro (40389458)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 6.  SHIGEMATSU Akio (30037428)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  尾方 純一 (50352331)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  KAMOCHI Masayuki (90204643)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  UETA Yoichi (10232745)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  SHIGA Yousuke (10399199)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  HORISHITA Reiko (40746658)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 12.  渋谷 泉 (50162649)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  松井 稔 (50282611)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  緒方 裕一 (80746660)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  濱田 高太郎 (70461580)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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