Iizuka Takashi 飯塚崇

… Alternative Names

IIZUKA Takasi 飯塚崇

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Researcher Number	40372932
Affiliation (Current)	2025: 順天堂大学, 医学部, 非常勤助教
Affiliation (based on the past Project Information) *help	2015 – 2022: 順天堂大学, 医学部, 非常勤助教 2009 – 2015: Juntendo University, 医学部, 助教
Review Section/Research Field	Principal Investigator Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related Except Principal Investigator Otorhinolaryngology
Keywords	Principal Investigator 遺伝子治療 / 遺伝性難聴 / 難聴治療 / 遺伝子導入 / ウイルスベクター / 難聴モデルマウス / 蝸牛ギャップ結合 / アデノ随伴ウィルスベクター / 遺伝子難聴 / GJB2 / コネキシン / モデルマウス … More Except Principal Investigator … More 遺伝性難聴 / iPS細胞 / 蝸牛線維細胞 / 内耳有毛細胞 / 多能性幹細胞 / 内耳前駆細胞 / 再生医療 / GJB2 / 内耳 / アデノ随伴ウィルス / 遺伝子治療 / 幹細胞ホーミング / 遺伝子改変動物 / ゲノム編集 / ギャップ結合 / Gjb2 / 前庭機能 / トランスジェニックマウス / 前庭 / コネキシン26 / 細胞治療 / 分化誘導 / ラセン神経節細胞 / 有毛細胞 / 人工多能性幹細胞 / 聴覚障害 / アデノ随伴ウイルス / 耳科学 Less

Development of gene therapy for GJB2 related hearing loss targeting the mature mouse inner earPrincipal Investigator
- Principal Investigator
  
  Iizuka Takashi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Juntendo University
Restoration of inner ear gap junction with iPS derived model cell and genome editing
- Principal Investigator
  
  Ikeda Katsuhisa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University
Morphological analysis and gene therapy targeted the vestibular organ with Connexin 26 related hereditary deafness
- Principal Investigator
  
  OKADA Hiroko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University
Cell therapy and gene therapy targeting GJB2 associated hearing loss
- Principal Investigator
  
  Ikeda Katsuhisa
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University
Gjb2 gene transfer for Connexin26 associated hereditary deafnessPrincipal Investigator
- Principal Investigator
  
  Iizuka Takashi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University
Cell therapy using iPS derived cells for hearing loss against the degenerations of various cochlear cell types
- Principal Investigator
  
  IKEDA Katsuhisa
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University
Cell therapy for hereditary deafness using induced pluripotent stem cell
- Principal Investigator
  
  IKEDA Katsuhisa
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University
The strategy to gain hearing ability of the deaf model mouse by injecting into the cochleaPrincipal Investigator
- Principal Investigator
  
  IIZUKA Takashi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University
The strategy to gain hearing ability of the deaf model mousePrincipal Investigator
- Principal Investigator
  
  IIZUKA Takasi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Juntendo University

All 2016 2015 2014 2013 2012 2011 2010 2009

All Journal Article Presentation

[Journal Article] Surgical Management of Myringosclerosis over an Entire Perforated Tympanic Membrane by Simple Underlay Myringoplasty.2016
- Author(s)
  Furukawa M, Hayashi C, Narabayashi O, Kasai M, Okada H, Haruyama T, Minekawa A, Iizuka T, Ikeda K.
- Journal Title
  
  Int J Otolaryngol.
  
  Volume: 2016 Pages: 2894932-2894932
- DOI
  10.1155/2016/2894932
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462567
[Journal Article] Perinatal Gjb2 gene transfer rescues hearing in a mouse model of hereditary deafness.2015
- Author(s)
  Iizuka T, Kamiya K, Gotoh S, Sugitani Y, Suzuki M, Noda T, Minowa O, Ikeda K.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: epub
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670721
[Journal Article] Perinatal Gjb2 gene transfer rescues hearing in a mouse model of hereditary deafness.2015
- Author(s)
  Izuka T., Kamiya K., Gotoh S., Sugitani Y., Suzuki M., Noda T., Minowa O., Ikeda K.
- Journal Title
  
  Hum. Mol.Genet.
  
  Volume: 24)13) Issue: 13 Pages: 3651-3661
- DOI
  10.1093/hmg/ddv109
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06726, KAKENHI-PROJECT-26462567, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25462653, KAKENHI-PROJECT-25462654, KAKENHI-PROJECT-25293351
[Journal Article] Postnatal Development and Maturation of the Vestibular Organ in Dominant-Negative Connexin 26 Transgenic Mouse.2015
- Author(s)
  Hiroko Okada, Kazusaku Kamiya., Takashi Iizuka and Katsuhisa Ikeda.
- Journal Title
  
  J Otol Rhinol
  
  Volume: S1 Pages: 37-40
- DOI
  10.4172/2324-8785.s1-009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462567, KAKENHI-PROJECT-25462653, KAKENHI-PROJECT-25462654, KAKENHI-PROJECT-25293351
[Journal Article] Perinatal Gjb2 gene transfer rescues hearing in a mouse model of hereditary deafness.2015
- Author(s)
  Iizuka T, Kamiya K, Gotoh S, Sugitani Y, Suzuki M, Noda T, Minowa O, Ikeda K.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: epub
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293351
[Journal Article] Assembly of the cochlear gap junction macromolecular complex requires connexin 26.2014
- Author(s)
  Kamiya K, Yum SW, Kurebayashi N, Muraki M, Ogawa K, Karasawa K, Miwa A, Guo X, Gotoh S, Sugitani Y, Yamanaka H, Ito-Kawashima S, Iizuka T, Sakurai T, Noda T, Minowa O, Ikeda K.
- Journal Title
  
  J Clin Invest,
  
  Volume: 124 Issue: 4 Pages: 1598-1607
- DOI
  10.1172/jci67621
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22110007, KAKENHI-PROJECT-24501325, KAKENHI-PROJECT-24590331, KAKENHI-PUBLICLY-25136718, KAKENHI-PROJECT-25293351, KAKENHI-PROJECT-25462653, KAKENHI-PROJECT-25670721, KAKENHI-PROJECT-221S0001
[Journal Article] Mumps virus infection with laryngeal edema and thoracic wall phlegmonous inflammation in an adult2013
- Author(s)
  Iizuka T, Kusuniki T, Ono N, Ikeda K
- Journal Title
  
  BMJ Case Rep
  
  Volume: 2013 Pages: bcr2012007829-bcr2012007829
- DOI
  10.1136/bcr-2012-007829
- Data Source
  KAKENHI-PROJECT-23791938
[Journal Article] Gene transfer targeting mouse vestibule using adenovirus and adeno-associated virus vectors2012
- Author(s)
  Hiroko Okada, Takashi Iizuka, Hideki Mochizuki, Tomoko Nihira, Kazusaku Kamiya, Ayako Inoshita, Hiromi Kasagi, Misato Kasai, Katsuhisa Ikeda
- Journal Title
  
  Otology & Neurotology
  
  Volume: 33(4) Pages: 655-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659799
[Journal Article] Atypical Lemierre syndrome, thrombophlelitis of the facial vein2012
- Author(s)
  Iizuka T, Nagaya K, Sasaki D, Haruyama T, Kojima M, Isogai H, Yoshikawa H, Ikeda K
- Journal Title
  
  Am J Em Med
  
  Volume: S0735-6757(12)[Epub ahead of print] Issue: 2 Pages: 400-7
- DOI
  10.1016/j.ajem.2012.08.006
- Data Source
  KAKENHI-PROJECT-23791938
[Journal Article] Giant cell tumor of the temporal bone with direct invasion into the middle ear and skull base: a case report2012
- Author(s)
  Iizuka T, Furukawa M, Ishii H, Kasai M, Hayashi C, Arai H, Ikeda K
- Journal Title
  
  Case Reports of Otolaryngology
- Data Source
  KAKENHI-PROJECT-23791938
[Journal Article] 薬剤性肝障害にて死亡した急性浸潤型副鼻腔真菌症例2012
- Author(s)
  飯塚崇,岡田弘子,畠将晃,村田潤子,池田勝久
- Journal Title
  
  耳鼻臨床
  
  Volume: 105(5) Pages: 437-440
- NAID
  10030600936
- Data Source
  KAKENHI-PROJECT-23791938
[Journal Article] Gene transfer targeting mouse vestibule using adenovirus and adeno-associated virus vectors2012
- Author(s)
  Okada H, Iizuka T, Mochizuki H, Nihira T,Kamiya K, Inoshita A, Kasagi H, Kasai M, Ikeda K
- Journal Title
  
  Otol Neurotol
  
  Volume: 33(4) Pages: 655-9
- Data Source
  KAKENHI-PROJECT-23791938
[Journal Article] A case of retropharyngeal abscess with spondylitis causing tetraplegia2012
- Author(s)
  Kusunoki T, Ito S, Iizuka T, Ono N, Ikeda K
- Journal Title
  
  Clinics and Practice
  
  Volume: 52(2) Pages: 123-4
- Data Source
  KAKENHI-PROJECT-23791938
[Journal Article] 咽喉頭部に皮診を認め、両側顔面神経麻痺を呈した水痘帯状疱疹ヘルペス感染症の 1例2011
- Author(s)
  深野崇之, 深江治郎, 高梨雅史, 飯塚崇, 服部信孝
- Journal Title
  
  神経内科
  
  Volume: 74(4) Pages: 427-429
- Data Source
  KAKENHI-PROJECT-23791938
[Journal Article] Bacteriologic evaluation of sinus aspirates taken by balloon catheter devices in chronic rhinosinusitis: preliminary study2011
- Author(s)
  Ikeda K, Ono N, Iizuka T, Kase K, Minekawa A, Inoshita A, Kusunoki T
- Journal Title
  
  ORL
  
  Volume: 73(5) Pages: 271-4
- Data Source
  KAKENHI-PROJECT-23791938
[Journal Article] 頸静脈孔傍神経節腫と鑑別困難であった頸静脈孔髄膜腫例2011
- Author(s)
  林千江里, 古川正幸, 春山琢男, 奈良林修, 飯塚崇, 池田勝久
- Journal Title
  
  耳鼻臨床
  
  Volume: 104(8)
- NAID
  10029260321
- Data Source
  KAKENHI-PROJECT-23791938
[Journal Article] GJB2 遺伝性難聴者の平衡機能の解析2011
- Author(s)
  笠井美里, 林千江里, 飯塚崇, 井下綾子, 神谷和作, 岡田弘子, 中島幸則, 加我君孝, 池田勝久
- Journal Title
  
  頭頸部自律神経
  
  Volume: 25 Pages: 24-28
- Data Source
  KAKENHI-PROJECT-23791938
[Journal Article] 深頸部膿瘍より降下性壊死性縦隔炎に至った2例2010
- Author(s)
  藤巻充寿, 伊藤伸, 大峡慎一, 飯塚崇, 楠威志、池田勝久
- Journal Title
  
  耳鼻咽喉科臨床補126
  
  Pages: 73-79
- NAID
  10026217790
- Data Source
  KAKENHI-PROJECT-21791647
[Journal Article] 咽喉頭異常感症に対するPPI(Proton Pump Inhibitor)の臨床的評価2010
- Author(s)
  林千江里, 横井秀格, 一針幸子, 横井尚子, 飯塚崇, 古川正幸, 池田勝久
- Journal Title
  
  耳鼻咽喉科臨床補126
  
  Pages: 30-32
- Data Source
  KAKENHI-PROJECT-21791647
[Journal Article] Vestibular function of patients with profound deafness related to GJB2 mutation.2010
- Author(s)
  Kasai M, Hayashi C, Iizuka T, Inoshita A, Kamiya K, Okada H, Nakajima Y, Kaga K, Ikeda K.
- Journal Title
  
  Acta Otolaryngol. 130(9)
  
  Pages: 990-995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791647
[Journal Article] 味覚障害と中耳真珠腫の進展度分類についての検討2010
- Author(s)
  岡田弘子, 古川正幸, 飯塚崇, 池田勝久
- Journal Title
  
  Facial Nerve Research. 29巻
  
  Pages: 151-152
- NAID
  10026103491
- Data Source
  KAKENHI-PROJECT-21791647
[Journal Article] 栄養血管が同定できなかった鼓室型グロームス腫瘍例2010
- Author(s)
  古川正幸, 春山琢男, 林千江里, 奈良林修, 杉田玄, 飯塚崇, 笠井美里, 池田勝久
- Journal Title
  
  耳鼻咽喉科臨床補126
  
  Pages: 6-9
- NAID
  10026217614
- Data Source
  KAKENHI-PROJECT-21791647
[Journal Article] 真珠腫性中耳炎症例における乳突洞の細菌学的検討2010
- Author(s)
  飯塚崇, 古川正幸, 笠井美里, 池田勝久
- Journal Title
  
  日本耳鼻咽喉科感染症研究会会誌 28(1)
  
  Pages: 55-57
- Data Source
  KAKENHI-PROJECT-21791647
[Journal Article] 中耳奇形症例の顔面神経走行異常の検討2010
- Author(s)
  飯塚崇, 古川正幸, 岡田弘子, 池田勝久
- Journal Title
  
  Facial Nerve Research. 29巻
  
  Pages: 34-36
- NAID
  10026103199
- Data Source
  KAKENHI-PROJECT-21791647
[Journal Article] 幼弱期のGjb2変異マウスの歪耳音響放射(DPOAE)の測定及び外有毛細胞の機能評価2010
- Author(s)
  峯川明, 成井裕弥, 井下綾子, 飯塚崇, 安部尚央, 欠畑誠治, 木谷令, 新川秀一, 小池卓二, 池田勝久
- Journal Title
  
  頭頸部自律神経 24
  
  Pages: 10-14
- Data Source
  KAKENHI-PROJECT-21791647
[Journal Article] Lipo-PGE1の突発性難聴に対する有効性2010
- Author(s)
  飯塚崇, 笠井美里, 春山琢男, 峯川明, 齊藤達矢, 林千江里, 八尾亨, 酒井陽子, 一針幸子, 横井尚子, 横井秀格, 古川正幸, 関眞規子, 楠威志, 池田勝久
- Journal Title
  
  耳鼻咽喉科臨床補126
  
  Pages: 10-14
- NAID
  10021299777
- Data Source
  KAKENHI-PROJECT-21791647
[Journal Article] Deveropment of distortion product otoacoustic emissions in C57B1/6J mice.2009
- Author(s)
  Narui Y, Minekawa A, Iizuka T, Furukawa M, Kusunoki T, Koike T, Ikeda K
- Journal Title
  
  Int J Audiol. 48(8)
  
  Pages: 576-581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791647
[Journal Article] Cochlear outer hair cells in a dominant-negative connexin26 mutant mouse preserve non-linear capacitance in spite of impaired distortion product otoacoustic emission.2009
- Author(s)
  Minekawa A, Abe T, Inoshita A, Iizuka T, Kakehata S, Narui Y, Koike T, Kamiya K, Okamura HO, Shinkawa H, Ikeda K.
- Journal Title
  
  Neuroscience. 164(3)
  
  Pages: 1312-1319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791647
[Presentation] Hearing improvement by gene therapy in a mouse model created by a conditional knockout of Gjb2 gene, preliminary study2013
- Author(s)
  Takashi Iizuka
- Organizer
  Association for Research in Otolaryngology
- Place of Presentation
  Baltimore Marriott Waterfront Hotel
- Data Source
  KAKENHI-PROJECT-23791938
[Presentation] Ｇｊｂ２コンディショナルノックアウトマウスへの遺伝子導入による聴力獲得2012
- Author(s)
  飯塚崇
- Organizer
  日本耳科学会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23791938
[Presentation] Hearing improvement by gene therapy in a mouse model created by a conditional knockout of Gjb2 gene, preliminary study.2012
- Author(s)
  Takashi Iizuka
- Organizer
  Association for Research in Otolaryngology
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23791938
[Presentation] Ｇｊｂ２コンディショナルノックアウトマウスへの遺伝子導入による聴力獲得2012
- Author(s)
  飯塚崇
- Organizer
  日本耳鼻咽喉科学会
- Place of Presentation
  新潟コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23791938
[Presentation] Inner ear biology2010
- Author(s)
  飯塚崇
- Organizer
  Intracochlear injection of adeno-associate virus vector carrying Gjb2 gene to a mouse model created by a conditional knockout of Gjb2 gene
- Place of Presentation
  チェコ・プラハ
- Year and Date
  2010-03-31
- Data Source
  KAKENHI-PROJECT-21791647
[Presentation] Intracochlear injection of adeno-associate virus vector carrying Gjb2 gene to a mouse model created by a conditional knockout of Gjb2 gene2010
- Author(s)
  飯塚崇
- Organizer
  Inner ear biology
- Place of Presentation
  チェコ・プラハ
- Year and Date
  2010-08-31
- Data Source
  KAKENHI-PROJECT-21791647

1. KAMIYA Kazusaku (10374159)

# of Collaborated Projects: 9 results

# of Collaborated Products: 6 results
2. IKEDA Katsuhisa (70159614)

# of Collaborated Projects: 6 results

# of Collaborated Products: 12 results
3. MINOWA Osamu (00181967)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. OKADA Hiroko (20433774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 井下綾子 (00514762)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 安齋崇 (20624852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 赤松和土 (60338184)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 城所淑信 (60514487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SUGITANI Yoshinobu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 桜井正樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Iizuka Takashi 飯塚 崇

IIZUKA Takasi 飯塚 崇

Research Projects

Research Products

Co-Researchers

Development of gene therapy for GJB2 related hearing loss targeting the mature mouse inner earPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Restoration of inner ear gap junction with iPS derived model cell and genome editing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Morphological analysis and gene therapy targeted the vestibular organ with Connexin 26 related hereditary deafness

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cell therapy and gene therapy targeting GJB2 associated hearing loss

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gjb2 gene transfer for Connexin26 associated hereditary deafnessPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cell therapy using iPS derived cells for hearing loss against the degenerations of various cochlear cell types

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cell therapy for hereditary deafness using induced pluripotent stem cell

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The strategy to gain hearing ability of the deaf model mouse by injecting into the cochleaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The strategy to gain hearing ability of the deaf model mousePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Surgical Management of Myringosclerosis over an Entire Perforated Tympanic Membrane by Simple Underlay Myringoplasty.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Perinatal Gjb2 gene transfer rescues hearing in a mouse model of hereditary deafness.2015

Author(s)

Journal Title

Data Source

[Journal Article] Perinatal Gjb2 gene transfer rescues hearing in a mouse model of hereditary deafness.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Postnatal Development and Maturation of the Vestibular Organ in Dominant-Negative Connexin 26 Transgenic Mouse.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Perinatal Gjb2 gene transfer rescues hearing in a mouse model of hereditary deafness.2015

Author(s)

Iizuka Takashi 飯塚崇

IIZUKA Takasi 飯塚崇