Takahata Masahiko 高畑雅彦

… Alternative Names

TAKAHATA Masahiko 高畑雅彦

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Researcher Number	40374368
Other IDs	https://orcid.org/0000-0002-2436-2175
External Links
Affiliation (Current)	2024: 獨協医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2024: 獨協医科大学, 医学部, 准教授 2017 – 2023: 北海道大学, 医学研究院, 准教授 2017: 北海道大学, 大学病院, 准教授 2016 – 2017: 北海道大学, 大学病院, 講師 2016: 北海道大学, 医学研究科, 講師 … More 2015: 北海道大学, 医学(系)研究科(研究院), 講師 2012 – 2013: 北海道大学, 大学病院, 講師 2011 – 2013: 北海道大学, 北海道大学病院, 講師 2011: 北海道大学, 北海道大学病院, 助教 2011: 北海道大学, 大学病院, 助教 Less
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields Except Principal Investigator Basic Section 56020:Orthopedics-related / Orthopaedic surgery / Materials/Mechanics of materials
Keywords	Principal Investigator 破骨細胞 / シグレック１５ / ステロイド / 骨粗鬆症 / シグレック / Siglec-15 / 免疫グロブリン様受容体 / 糖鎖 / 骨吸収 / 統合ゲノミクス … More / 空間トランスクリプトーム解析 / 脊柱靱帯骨化症 / 便マイクロバイオーム / 腸管免疫 / 慢性炎症 / 慢性骨髄炎 / がん溶骨性骨転移 / 自己免疫性関節炎 / がん免疫 / 末梢性免疫寛容誘導 / 骨破壊 / 末梢性免疫寛容誘導機構 / 免疫チェックポイント / 骨吸収抑制薬 / 骨吸収抑制剤 / 骨破壊性疾患 / 免疫受容体 / 骨脆弱性 / 骨質 / 骨質異常 / 関節リウマチ / 糖鎖受容体 / シアル酸 / 細胞融合 / 細胞骨格 / シグレック 15 … More Except Principal Investigator 糖脂質 / 骨代謝 / 遺伝子 / 肥満 / OPLL / 変形性関節症 / ガングリオシド / 破骨細胞 / 骨粗鬆症 / 骨折 / 脊柱後縦靱帯骨化症 / レプチン / 脊柱靱帯骨化症 / 若年者由来歯髄幹細胞 / 骨再生 / 内臓脂肪 / シングルセル / 炎症回路（炎症アンプ） / 異栄養性石灰化 / 線維芽細胞 / 靭帯 / ピロリン酸代謝 / IL-6 / 炎症アンプ / 石灰化抑制機構 / 慢性炎症 / 異所性石灰化 / 次世代シーケンサー / 一塩基多型 (SNP) / アディポカイン / ビタミンB6 / ビタミンA / 異所性靭帯骨化 / 栄養素 / 異所性骨化 / 脊椎靭帯骨化 / 2型糖尿病 / ゲノムワイド相関解析 / 後縦靭帯骨化症 / obesity / gene / GWAS / 老化 / 細胞・組織 / 複合材料・物性 / 生体材料 / 生物・生体工学 / 機械材料・材料力学 / 分析科学 / マイクロCT / 力学特性 / 蛍光顕微鏡 / ステロイド性骨粗鬆症 / 赤外分光法 / 配向性 / 骨密度 / 赤外イメージング / 骨強度 / 骨質 / ステロイド / 関節病学 / 糖鎖認識分子 / 癌認識分子 / 骨巨細胞腫 / 転移性骨腫瘍 / 免疫受容体 / 糖認識分子 / 癌糖鎖抗原 / 骨・軟骨代謝 / 骨 / 軟骨 / 遺伝子改変マウス / スフィンゴ糖脂質 / 骨・軟骨代謝学 / 糖蛋白質 / シアリル糖鎖 / RANKL / 細胞融合 / レクチン / 糖鎖受容体 / 脂質ラフト / 糖鎖 / 骨吸収 / 構造解析 / 脊椎骨折 / 骨癒合過程 / 脊椎固定術 / 骨移植 / 骨代謝改善薬 / medication / vertebral fracture / osteoporosis Less

統合ゲノミクスによる脊柱靭帯骨化症の発症機構の解明Principal Investigator
- Principal Investigator
  
  高畑雅彦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Dokkyo Medical University
レプチンシグナルを介した肥満による脊柱靱帯骨化進展機構の解明
- Principal Investigator
  
  種市洋
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Dokkyo Medical University
遺伝学的アプローチによる脊柱後縦靭帯骨化症に対する治療/予防法の開発
- Principal Investigator
  
  小池良直
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Hokkaido University
脊椎靭帯組織における異所性骨化に関連する遺伝的要因の網羅的探索
- Principal Investigator
  
  遠藤努
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Hokkaido University
Gut microbiome-Osteal macrophages axis as a new therapeutic target for prevention of osteoporosisPrincipal Investigator
- Principal Investigator
  
  高畑雅彦
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Hokkaido University
若年者歯髄由来幹細胞を用いた高齢者難治骨折治療法の開発
- Principal Investigator
  
  藤田諒
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Hokkaido University
破骨細胞に発現する免疫チェックポイント分子シグレック-15の機能と治療応用Principal Investigator
- Principal Investigator
  
  高畑雅彦
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Hokkaido University
Disruption of biomineralization suppression mechanisms by chronic inflammation
- Principal Investigator
  
  Ota Masahiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Hokkaido University
Genetic predisposition and environmental factors associated with obesity/glucose intolerance in posterior longitudinal ligament ossification
- Principal Investigator
  
  ENDO TSUTOMU
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Hokkaido University
Development of antiresorptive therapy targeting immunoglobulin-like receptorsPrincipal Investigator
- Principal Investigator
  
  Takahata Masahiko
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Hokkaido University
Elucidation of pathophysiology of joint disease based on analysis of glycosphingolipid function and development of novel treatment
- Principal Investigator
  
  Iwasaki Norimasa
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Hokkaido University
Research for in vivo assessment of bone quality in glucocorticoid-induced osteoporosis
- Principal Investigator
  
  Suda (Kimura-Suda) Hiromi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Chitose Institute of Science and Technology
Investigation of the mechanism of osteolytic bone destruction in bone metastasis via tumor-associated carbohydrate antigen
- Principal Investigator
  
  Arai Ryuta
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Hokkaido University
Bone Tissue Mechanics under Deformation with Interaction between Molecla and Crystal of HAP and Micro Structure
- Principal Investigator
  
  TADANO SHIGERU
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Materials/Mechanics of materials
- Research Institution
  Hakodate National College of Technology
  Hokkaido University
Mechanisms of bone fragility in patients with rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  Takahata Masahiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Hokkaido University
Functional analysis of glycosphingolipids in osteochondral homeostasis using knockout mice
- Principal Investigator
  
  IWASAKI Norimasa
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Hokkaido University
Sialic acid binding immunoglobulin like lectin regulates osteoclast differentiation and function in destructive bone diseasesPrincipal Investigator
- Principal Investigator
  
  TAKAHATA Masahiko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Hokkaido University
Experimental Study for Appropriate Medication for Osteoporotic Fragile Vertebral Fracture
- Principal Investigator
  
  ABUMI Kuniyoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Hokkaido University
Elucidating the bone resorption mechanism using a glycobiological approach
- Principal Investigator
  
  IWASAKI Norimasa
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Hokkaido University

All 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Association Between Vitamin A Intake and Disease Severity in Early-Onset Heterotopic Ossification of the Posterior Longitudinal Ligament of the Spine2021
- Author(s)
  Endo Tsutomu、Imagama Shiro、Kato Satoshi、Kaito Takashi、Sakai Hiroaki、Ikegawa Shiro、Kawaguchi Yoshiharu、Kanayama Masahiro、Hisada Yuichiro、Koike Yoshinao、Ando Kei、Kobayashi Kazuyoshi、Oda Itaru、Okada Kazufumi、Takagi Ryo、Iwasaki Norimasa、Takahata Masahiko
- Journal Title
  
  Global Spine Journal
  
  Volume: Online ahead of print Issue: 8 Pages: 1-11
- DOI
  10.1177/2192568221989300
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09545, KAKENHI-PROJECT-19K09566
[Journal Article] Relationships among Collagen Fiber Orientation, Mineralization, Mineral Maturity, and Crystallinity2020
- Author(s)
  Hiromi Kimura-Suda, Fumiya Nakamura, Ryota Oseto, Yuya Kanehira, Dai Sato, Ryo Fujita, Masahiro Ota, Masahiko Takahata
- Journal Title
  
  Molecular Crystals and Liquid Crystals
  
  Volume: － Issue: 1 Pages: 154-160
- DOI
  10.1080/15421406.2020.1743467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10916
[Journal Article] Clinical characteristics of patients with thoracic myelopathy caused by ossification of the posterior longitudinal ligament.2020
- Author(s)
  Endo T, Takahata M, Koike Y, Iwasaki N
- Journal Title
  
  J Bone Miner Metab.
  
  Volume: 38 Issue: 1 Pages: 63-69
- DOI
  10.1007/s00774-019-01026-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09566
[Journal Article] Siglec-15-targeting therapy protects against glucocorticoid-induced osteoporosis of growing skeleton in juvenile rats.2020
- Author(s)
  Sato D, Takahata M, Ota M, Fukuda C, Hasegawa T, Yamamoto T, Amizuka N, Tsuda E, Okada A, Hiruma Y, Fujita R, Iwasaki N.
- Journal Title
  
  Bone
  
  Volume: 135 Pages: 115331-115331
- DOI
  10.1016/j.bone.2020.115331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04309
[Journal Article] Magnetic resonance imaging T1 and T2 mapping provide complementary information on the bone mineral density regarding cancellous bone strength in the femoral head of postmenopausal women with osteoarthritis2019
- Author(s)
  Kaori Endo, Masahiko Takahata, Hiroyuki Sugimori, Satoshi Yamada, Shigeru Tadano, Jeffrey Wang, Masahiro Todoh, Yoichi M. Ito, Daisuke Takahashi, Kohsuke Kudo, Norimasa Iwasaki
- Journal Title
  
  Clinical Biomechanics
  
  Volume: 65 Pages: 13-18
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02207
[Journal Article] Quick and easy sample preparation without resin embedding for the bone quality assessment of fresh calcified bone using fourier transform infrared imaging2018
- Author(s)
  Hiromi Kimura-Suda, Masahiko Takahata, Teppei Ito, Tomohiro Shimizu, Kyosuke Kanazawa, Masahiro Ota, Norimasa Iwasaki
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 2 Pages: e0189650-e0189650
- DOI
  10.1371/journal.pone.0189650
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10916
[Journal Article] Efficacy and safety of osteoporosis medications in a rat model of late-stage chronic kidney disease accompanied by secondary hyperparathyroidism and hyperphosphatemia.2017
- Author(s)
  Ota M, Takahata M, Shimizu T, Kanehira Y, Kimura-Suda H, Kameda Y, Hamano H, Hiratsuka S, Sato D, Iwasaki N.
- Journal Title
  
  Osteoporosis International
  
  Volume: 28 Issue: 4 Pages: 1481-1490
- DOI
  10.1007/s00198-016-3861-7
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16670, KAKENHI-PROJECT-15H02207
[Journal Article] Autoimmune arthritis deteriorates bone quantity and quality of periarticular bone in a mouse model of rheumatoid arthritis2016
- Author(s)
  Shimizu T.、Takahata M.、Kimura-Suda H.、Kameda Y.、Endo K.、Hamano H.、Hiratsuka S.、Ota M.、Sato D.、Ito T.、Todoh M.、Tadano S.、Iwasaki N.
- Journal Title
  
  Osteoporosis International
  
  Volume: 28 Issue: 2 Pages: 709-718
- DOI
  10.1007/s00198-016-3781-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02207
[Journal Article] Structural strength of cancellous cubic specimens under cyclic compression2016
- Author(s)
  Kaori Endo, Satoshi Yamada, Masahiro Todoh, Masahiko Takahata, Norimasa Iwasaki, Shigeru Tadano
- Journal Title
  
  Peer J
  
  Volume: 4 Pages: 1-15
- DOI
  10.7717/peerj.1562
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02207
[Journal Article] Sialic acid-binding immunoglobulin-like lectin 15 (Siglec-15) mediates periarticular bone loss, but not joint destruction, in murine antigen-induced arthritis.2015
- Author(s)
  Shimizu T, Takahata M, Kameda Y, Endo T, Hamano H, Hiratsuka S, Ota M, Iwasaki N
- Journal Title
  
  Bone
  
  Volume: 79 Pages: 65-70
- DOI
  10.1016/j.bone.2015.05.029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462357
[Journal Article] Siglec-15 regulates osteoclast differentiation by modulating RANKL-induced phosphatidylinositol 3-kinase/Akt and Erk pathways in association with signaling adaptor DAP122013
- Author(s)
  Kameda Y, Takahata M, Komatsu M, et al
- Journal Title
  
  J Bone Miner Res
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890008
[Presentation] 成人期早・中期の肥満による脊柱後縦靭帯骨化症重症化と脂肪由来生理活性分子アディポカインの特徴的分泌パターン2021
- Author(s)
  小池良直、高畑雅彦、遠藤努，今釜史郎，加藤仁志，坂井宏旭，海渡貴司，金山雅弘，川口善治，岩崎倫政
- Organizer
  第140回北海道整形災害外科学会
- Data Source
  KAKENHI-PROJECT-19K09566
[Presentation] ステロイド性骨粗鬆症モデルラットにおける骨強度・骨密度・骨質の関係2020
- Author(s)
  中村郁哉, 佐藤大, 藤田諒, 長谷川智香, 堀内秀与, 枡谷朋美, 太田昌博, 高畑雅彦, 居城邦治, 網塚憲生, 木村-須田廣美
- Organizer
  第32回北海道骨粗鬆症研究会学術集会
- Data Source
  KAKENHI-PROJECT-16K10916
[Presentation] 胸椎後縦靭帯骨化症の骨化進展に関与する補酵素（ビタミン）の血清学的評価2020
- Author(s)
  遠藤努，高畑雅彦，小池良直，久田雄一郎，岩崎倫政、今釜史郎，安藤圭，小林和克，加藤仁志，海渡貴司，金山雅弘，川口善治，坂井宏旭，池川志郎
- Organizer
  日本脊椎脊髄病学会
- Data Source
  KAKENHI-PROJECT-19K09566
[Presentation] ステロイド性骨粗鬆症ラットの腰椎の骨質は，大腿骨の骨質に比べて緩やかに変化する2020
- Author(s)
  中村郁哉, 兼平裕也, 佐藤大, 藤田諒, 長谷川智香, 堀内秀与，枡谷朋美, 太田昌博, 高畑雅彦, 居城邦治, 網塚憲生, 木村-須田廣
- Organizer
  第38回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10916
[Presentation] 胸椎後縦靭帯骨化症の重症化に関与する補酵素（ビタミン）の血清学的評価2020
- Author(s)
  遠藤努，高畑雅彦，小池良直，岩崎倫政、今釜史郎，安藤圭，小林和克，加藤仁志，海渡貴司，金山雅弘，川口善治，坂井宏旭，池川志郎
- Organizer
  日本整形外科学会
- Data Source
  KAKENHI-PROJECT-19K09566
[Presentation] ステロイド性骨粗鬆症モデルラットにおける骨強度と骨密度および骨質の関係2020
- Author(s)
  中村郁哉, 佐藤大, 藤田諒, 長谷川智香, 堀内秀与, 枡谷朋美, 太田昌博, 高畑雅彦, 居城邦治, 網塚憲生, 木村-須田廣美
- Organizer
  第40回日本骨形態計測学会
- Data Source
  KAKENHI-PROJECT-16K10916
[Presentation] ステロイド性骨粗鬆症ラット大腿骨の３次元的骨質解析2019
- Author(s)
  中村郁哉、大瀬戸椋大、鎌田賢、兼平裕也、藤田諒、佐藤大、太田昌博、高畑雅彦、木村-須田廣美
- Organizer
  第53回高分子学会北海道支部研究発表会
- Data Source
  KAKENHI-PROJECT-16K10916
[Presentation] 赤外イメージングによるステロイド性骨粗鬆症の骨質解析2019
- Author(s)
  中村郁哉、大瀬戸椋大、鎌田賢、兼平裕也、佐藤大、藤田諒、太田昌博、高畑雅彦、木村-須田廣美
- Organizer
  第31回北海道骨粗鬆症研究会学術集会
- Data Source
  KAKENHI-PROJECT-16K10916
[Presentation] ステロイド性骨粗鬆症ラット大腿骨の骨質解析2019
- Author(s)
  中村郁哉, 大瀬戸椋大, 兼平裕也, 佐藤大, 藤田諒, 太田昌博, 小林大二, 高畑雅彦, 木村-須田廣美
- Organizer
  第39回日本骨形態計測学会
- Data Source
  KAKENHI-PROJECT-16K10916
[Presentation] ステロイド性骨粗鬆症を発症したラット大腿骨では皮質骨幅の減少と二次海綿骨の骨吸収を認めたが，一次海綿骨と皮質骨骨内膜・骨膜側では骨形成を確認した2019
- Author(s)
  中村郁哉, 大瀬戸椋大, 兼平裕也, 佐藤大, 藤田諒, 堀内秀与, 枡谷朋美, 古川翔太, 高畑雅彦, 木村-須田廣美
- Organizer
  第37回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10916
[Presentation] Relationships between Collagen Fiber Orientation, Mineralization, Mineral Maturity, and Crystallinity2019
- Author(s)
  Fumiya Nakamura, Ryota Oseto, Yuya Kanehira, Dai Sato, Ryo Fujita, Masahiro Ota, Masahiko Takahata, Hiromi Kimura-Suda
- Organizer
  KJF-ICOMEP2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10916
[Presentation] ステロイド性骨粗鬆症ラット大腿骨におけるコラーゲン線維配向性と骨質パラメータの相関2019
- Author(s)
  中村郁哉, 大瀬戸椋大, 兼平裕也, 佐藤大, 藤田諒, 堀内秀与, 枡谷朋美, 古川翔太, 高畑雅彦, 木村-須田廣美
- Organizer
  第23回生体関連セラミックス討論会
- Data Source
  KAKENHI-PROJECT-16K10916
[Presentation] 赤外二色性イメージングによるステロイド性骨粗鬆症ラット大腿骨の評価2019
- Author(s)
  大瀬戸椋大、兼平裕也、中村郁哉、藤田諒、佐藤大、太田昌博、高畑雅彦、木村-須田廣美
- Organizer
  第53回高分子学会北海道支部研究発表会
- Data Source
  KAKENHI-PROJECT-16K10916
[Presentation] Femoral bone quality in rats with glucocorticoid-induced osteoporosis after implantation of prednisolone pellet2019
- Author(s)
  Fumiya Nakamura, Ryota Oseto, Yuya Kanehira, Dai Sato, Ryo Fujita, Hideyo Horiuchi, Tomomi Masuya, Syota Furukawa, Masahiko Takahata, Hiromi Kimura-Suda
- Organizer
  ASBMR 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10916
[Presentation] ラット大腿骨の骨質因子と骨構造の関係2019
- Author(s)
  中村郁哉, 大瀬戸椋大, 兼平裕也, 佐藤大, 藤田諒, 太田昌博, 高畑雅彦, 木村-須田廣美
- Organizer
  第68回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-16K10916
[Presentation] Methods for assessing bone quality using FTIR imaging2018
- Author(s)
  Yuya Kanehira, Teppei Ito, Ryota Hara, Yuki Imabata, Masahiro Ota, Masahiko Takahata, Tomohiro Shimizu, Hiromi Kimura-Suda
- Organizer
  CIF 19th
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10916
[Presentation] Assessment of femoral bone quality in rats with glucocorticoid-induced osteoporosis2018
- Author(s)
  Fumiya Nakamura, Ryota Oseto, Yuya Kanehira, Teppei Ito, Dai Sato, Ryo Fujita, Masahiro Ota, Masahiko Takahata, Hiromi Kimura-Suda
- Organizer
  CIF 19th
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10916
[Presentation] Breast cancer cells expressing cancer-associated Sialyl-Tn antigen have less capacity to develop metastatic bone lesion in a mice model of bone metastasis.2017
- Author(s)
  Hamano H, Takahata M, Kameda Y, Arai R, Sato D, Ota M, Hiratsuka S, Shimizu T, Iwasaki N.
- Organizer
  Orthopaedic Research Society (ORS) 2016 Annual Meeting, March 5-8, 2016, Orland, Florida, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10427
[Presentation] MRI T1, T2 mappingによる海綿骨強度予測－ヒト臨床骨検体サンプルを用いた検討－2017
- Author(s)
  遠藤香織, 高畑雅彦, 杉森博行, Wang Jeffrey, 山田悟史, 但野茂, 東藤正浩, 伊藤陽一, 高橋大介, 清水智弘, 工藤與亮, 岩崎倫政
- Organizer
  第29回北海道骨粗鬆症研究会学術集会
- Data Source
  KAKENHI-PROJECT-15H02207
[Presentation] 転移性骨腫瘍の骨破壊進展における癌関連糖鎖抗原Sialyl-Tnの役割2017
- Author(s)
  濵野博基、高畑雅彦、亀田裕亮、清水智弘、平塚重人、太田昌博、佐藤　大、岩崎倫政
- Organizer
  第35回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10427
[Presentation] Effects of fixing and embedding on bone quality assessed using Fourier transform infrared imaging2017
- Author(s)
  Teppei Ito, Masahiko Takahata, Tomohiro Shimizu, Kyosuke Kanazawa, Hiromi Kimura-Suda
- Organizer
  CIF 18th
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10916
[Presentation] Bone quality assessment of fresh bone using FTIR imaging2017
- Author(s)
  Teppei Ito, Masahiko Takahata, Tomohiro Shimizu, Kyosuke Kanazawa, Hiromi Kimura-Suda
- Organizer
  ASBMR 2017 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10916
[Presentation] MRI T1 map value can be a surrogate for bone strength of cancellous bone2016
- Author(s)
  Kaori Endo, Masahiko Takahata, Hiroyuki Sugimori, Jeffrey Wang, Satoshi Yamada, Daisuke Takahashi, Masahiro Todoh, Shigeru Tadano, Kohsuke Kudo, Norimasa Iwasaki
- Organizer
  ORS2016 Annual Meeting
- Place of Presentation
  Disney's Coronado Springs Resort, Orlando, FL, (US)
- Year and Date
  2016-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02207
[Presentation] 関節リウマチでは皮質骨の骨質劣化により早期から骨脆弱性が生じる2015
- Author(s)
  清水智弘, 高畑雅彦, 亀田裕亮, 遠藤香織, 濱野博基, 平塚重人, 太田昌博, 伊藤哲平, 木村須田廣美, 東藤正浩, 但野茂, 岩崎倫政
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場（富山県富山市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-15H02207
[Presentation] ウシ海綿骨立方体試験片の繰返し圧縮時における強度特性2015
- Author(s)
  遠藤香織, 山田悟史, 東藤正浩, 高畑雅彦, 岩崎倫政, 但野茂
- Organizer
  日本機械学会2015年度年次大会
- Place of Presentation
  北海道大学 (北海道札幌市)
- Year and Date
  2015-09-14
- Data Source
  KAKENHI-PROJECT-15H02207
[Presentation] 関節リウマチでは早期から関節近傍皮質骨の骨質異常と骨脆弱性が生じる2015
- Author(s)
  清水智弘, 高畑雅彦, 亀田裕亮, 遠藤香織, 濱野博基, 平塚重人, 太田昌博, 伊藤哲平, 木村須田廣美, 東藤正浩, 但野茂, 岩崎倫政
- Organizer
  第33回日本骨代謝学会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-15H02207
[Presentation] 脆弱性骨折後圧潰進行リスクの予測因子－ウシ海綿骨試験片を用いた繰返し圧縮破壊試験による検討－2015
- Author(s)
  遠藤香織, 山田悟史, 高畑雅彦, 東藤正浩, 但野茂, 岩崎倫政
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場 (富山県富山市)
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-15H02207
[Presentation] 関節リウマチでは早期から関節近傍皮質骨の骨質異常と骨脆弱性が生じる2015
- Author(s)
  清水智弘, 高畑雅彦
- Organizer
  第33回日本骨代謝学会
- Place of Presentation
  京王プラザホテル（東京都　新宿区）
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-25462357
[Presentation] Structural Strength of Bovine Cancellous Cubic Specimens under Cyclic Compression2015
- Author(s)
  Kaori Endo, Satoshi Yamada, Masahiro Todoh, Masahiko Takahata, Norimasa Iwasaki, Shigeru Tadano
- Organizer
  8th Asian-Pacific Conference on Biomechanics
- Place of Presentation
  Hokkaido Univ. (Sapporo)
- Year and Date
  2015-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02207
[Presentation] 関節リウマチでは皮質骨の骨質劣化により早期から骨脆弱性が生じる2015
- Author(s)
  清水智弘, 高畑雅彦
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場（富山県　富山市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-25462357
[Presentation] 免疫グロブリン様レクチンSiglec-15はDAP12を介した共刺激シグナルに関与し破骨細胞分化を制御する2012
- Author(s)
  小松幹, 高畑雅彦
- Organizer
  Orthopedic Research Society 2012 Annual Meeting
- Place of Presentation
  Moscone West Convention Center, San Francisco, USA
- Data Source
  KAKENHI-PROJECT-23890008
[Presentation] A Member of Sialic Acid-Binding Immunoglobulin-Like lectin 15(Siglec-15) Associates with DAP12-mediated Costimulatory Signal in Osteoclastogenesis2012
- Author(s)
  Miki Komatsu, Masahiko Takahata, Norimasa Iwasaki.
- Organizer
  The orthopaedic Research Society(ORS) annual meeting 2012
- Place of Presentation
  米国: Moscone West Convention Center
- Data Source
  KAKENHI-PROJECT-21659346
[Presentation] 免疫グロブリン様レクチンSiglec-15はDAP12を介した共刺激シグナルに関与し破骨細胞分化を制御する2011
- Author(s)
  小松幹, 高畑雅彦
- Organizer
  日本骨代謝学会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2011-07-30
- Data Source
  KAKENHI-PROJECT-23890008
[Presentation] 免疫グロブリン様レクチンSiglec-15はDAP12を介した共刺激シグナルに関与し破骨細胞分化を制御する
- Author(s)
  小松幹,高畑雅彦,岩崎倫政
- Organizer
  第29回日本骨代謝学会
- Place of Presentation
  大阪市:大阪国際会議場
- Data Source
  KAKENHI-PROJECT-21659346

1. IWASAKI Norimasa (30322803)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
2. SUDA Hiromi (00574857)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
3. ENDO TSUTOMU (90805293)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
4. 寺尾知可史 (60610459)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. ABE Yuichiro (80547604)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. ONODERA Tomohiro (70547174)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. TODO Msahiro (10314402)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
8. 小池良直 (00992067)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. ABUMI Kuniyoshi (00159419)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HOJO Yoshihiro (60451423)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OSHIMA Shigeki (90547613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. AMIDUKA Norio (30242431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Arai Ryuta (40722509)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. TADANO SHIGERU (50175444)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
15. Ota Masahiro (70823334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 前田英次郎 (20581614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 横田秀夫 (00261206)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 藤崎和弘 (90435678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 山田悟史 (90730169)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
20. 古川潤一 (30374193)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 村上正晃 (00250514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 津田真寿美 (30431307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 照川アラー (00723074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 堀千明 (50722948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 藤田諒 (30908190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 鈴木穣 (40323646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 種市洋 (10261299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 川口善治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 清水智弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takahata Masahiko 高畑 雅彦

TAKAHATA Masahiko 高畑 雅彦

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統合ゲノミクスによる脊柱靭帯骨化症の発症機構の解明Principal Investigator

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Gut microbiome-Osteal macrophages axis as a new therapeutic target for prevention of osteoporosisPrincipal Investigator

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破骨細胞に発現する免疫チェックポイント分子シグレック-15の機能と治療応用Principal Investigator

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Development of antiresorptive therapy targeting immunoglobulin-like receptorsPrincipal Investigator

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Mechanisms of bone fragility in patients with rheumatoid arthritisPrincipal Investigator

Takahata Masahiko 高畑雅彦

TAKAHATA Masahiko 高畑雅彦