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Sato Taku  佐藤 卓

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Taku Sato  佐藤 卓

SATO Taku  佐藤 卓

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Researcher Number 40375259
Other IDs
Affiliation (Current) 2022: 東京医科歯科大学, 難治疾患研究所, 准教授
Affiliation (based on the past Project Information) *help 2020 – 2022: 東京医科歯科大学, 難治疾患研究所, 准教授
2018 – 2019: 東京医科歯科大学, 難治疾患研究所, 講師
2013 – 2015: 東京医科歯科大学, 難治疾患研究所, 非常勤講師
2011 – 2012: 東京医科歯科大学, 難治疾患研究所, 特任助教
2008: 東北大学, 医学部, 教授
2007 – 2008: Akita University, 医学部, 助教
2006: 秋田大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Immunology / Basic Section 49030:Experimental pathology-related / Biological Sciences / General medical chemistry / Biological pharmacy / Medium-sized Section 50:Oncology and related fields
Except Principal Investigator
Biological Sciences
Keywords
Principal Investigator
インターフェロン / 幹細胞性 / 組織幹細胞 / サイトカイン / 免疫学 / 細胞・組織 / 生体分子 / ウイルス / シダナル伝達 / シグナル伝達 … More / 抗原 / NOD1 / Cross-priming / dendritic cell / Cytotoxic T lymphocyte / Endotoxin shock / Nod1 / Dendritic cell / Cytotoxic T lymphocytes / 慢性骨髄性白血病 / 白血病幹細胞 / 細胞周期 / 造血幹細胞 / 表皮幹細胞 / 幹細胞 / 癌幹細胞 / 脳内炎症 / 炎症老化 / ミクログリア / 脳老化 / 遺伝子発現 / 全身老化 / 皮膚自己免疫疾患 / マクロファージ / 脂肪組織 / 間葉系幹細胞 / 皮膚エリテマトーデス / インタラクトーム / ヒトがんオルガノイド / 化学療法耐性 / がん幹細胞 / 自己分泌 / 治療抵抗性 / 腫瘍内癌不均一性 / ヒトがん … More
Except Principal Investigator
DC / poly I : C / I型IFN / NOD1 / NOD2 / クロスプライミング / 自然免疫 / TLR7 / TLR9 / TRAIL / DR5 / インフルエンザウィルス Less
  • Research Projects

    (9 results)
  • Research Products

    (26 results)
  • Co-Researchers

    (6 People)
  •  Elucidation of the changes in tissue stem cell-niche interactions that cause skin autoimmune disordersPrincipal Investigator

    • Principal Investigator
      佐藤 卓
    • Project Period (FY)
      2021 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Tokyo Medical and Dental University
  •  ヒト癌オルガノイドオライブラリーを利用した治療抵抗性癌の発生・維持機構解明Principal Investigator

    • Principal Investigator
      佐藤 卓
    • Project Period (FY)
      2021 – 2026
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      Tokyo Medical and Dental University
  •  Effect of interferon signals in the brain on the induction of systemic agingPrincipal Investigator

    • Principal Investigator
      Taku Sato
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Establishment of the eradication strategy for cancer stem cells by targeting IRF2Principal Investigator

    • Principal Investigator
      Sato Taku
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tokyo Medical and Dental University
  •  I型IFNの作用を利用した白血病幹細胞を標的とする白血病根治療法の創出Principal Investigator

    • Principal Investigator
      佐藤 卓
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  Significance of the interferon signal regulation in the maintenance of tissue stem cellsPrincipal Investigator

    • Principal Investigator
      SATO Taku
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Tokyo Medical and Dental University
  •  ウィルス抗原の提示における樹状細胞アポトーシスの免疫学的意義

    • Principal Investigator
      樗木 俊聡
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Akita University
  •  Nod1-mediated regulation of immunological homeostasisPrincipal Investigator

    • Principal Investigator
      SATO Taku, TADA Hiroyuki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Akita University
  •  転写因子IRF-3による抗原特異的メモリーT細胞維持の分子機構Principal Investigator

    • Principal Investigator
      佐藤 卓
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Immunology
    • Research Institution
      Akita University

All 2021 2020 2019 2018 2013 2012 2011 2009 2008 2007 2006

All Journal Article Presentation

  • [Journal Article] 腸管上皮幹細胞におけるインターフェロンの役割2021

    • Author(s)
      佐藤 卓, 樗木 俊聡
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 75 Pages: 759-764

    • NAID

      40022604527

    • Data Source
      KAKENHI-PROJECT-21H02712
  • [Journal Article] IRF2 maintains the stemness of colonic stem cells by limiting physiological stress from interferon.2020

    • Author(s)
      Minamide K*, Sato T*, Nakanishi Y, Ohno H, Kato T, Asano J, Ohteki T. (*: equal contribution)
    • Journal Title

      Sci Rep.

      Volume: 10 Pages: 14639-14639

    • DOI

      10.1038/s41598-020-71633-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07062
  • [Journal Article] Regulated IFN signalling preserves the stemness of intestinal stem cells by restricting differentiation into secretory-cell lineages.2020

    • Author(s)
      Sato T, Ishikawa S, Asano J, Yamamoto H, Fujii M, Sato T, Yamamoto K, Kitagaki K, Akashi T, Okamoto R, Ohteki T.
    • Journal Title

      Nat Cell Biol.

      Volume: 22 Pages: 919-919

    • DOI

      10.1038/s41556-020-0545-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H06176, KAKENHI-PROJECT-20H03757, KAKENHI-PROJECT-18K07062
  • [Journal Article] Autophagy Detection in Intestinal Stem Cells.2020

    • Author(s)
      Asano J*, Sato T*, Ohteki T. (*: equal contribution)
    • Journal Title

      Methods Mol Biol.

      Volume: 2171 Pages: 115-115

    • DOI

      10.1007/978-1-0716-0747-3_7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07062
  • [Journal Article] Characterization of radioresistant epithelial stem cell heterogeneity in the damaged mouse intestine2020

    • Author(s)
      Sato T, Sase M, Ishikawa S, Kajita M, Asano J, Sato T, Mori Y, and Ohteki T.
    • Journal Title

      Scientific Reports

      Volume: 10 Pages: 8308-8308

    • DOI

      10.1038/s41598-020-64987-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-18H05028, KAKENHI-PROJECT-19H01024, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-19J40198, KAKENHI-PROJECT-18K07062, KAKENHI-PROJECT-18K07258
  • [Journal Article] Novel interferon-based pre-transplantation conditioning in the treatment of a congenital metabolic disorder.2013

    • Author(s)
      Sato T, Ikeda M, Yotsumoto S, Shimada Y, Higuchi T, Kobayashi H, Fukuda T, Ohashi T, Suda T, Ohteki T.
    • Journal Title

      Blood.

      Volume: 121 Pages: 3267-73

    • Data Source
      KAKENHI-PROJECT-23790326
  • [Journal Article] Novel interferon-based pre-transplantation conditioning in the treatment of a congenital metabolic disorder.2013

    • Author(s)
      Sato T(他9名)
    • Journal Title

      Blood.

      Volume: 121 Pages: 3267-3273

    • DOI

      10.1182/blood-2012-07-443713

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23790326, KAKENHI-PROJECT-25460061
  • [Journal Article] IRF-2 protects quiescent HSCs from type-I interferondependent exhaustion2009

    • Author(s)
      Sato, T., Onai, N., Yoshihara, H., Arai, F., Suda, T., and Ohteki, T.
    • Journal Title

      Nat. Med. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590489
  • [Journal Article] IRF-2 protects quiescent HSCs from type-I interferon-dependent exhaustion2009

    • Author(s)
      Sato, T.
    • Journal Title

      Nature Medicine (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19041011
  • [Journal Article] 消化管免疫24.生体防御におけるIELおよび腸管DCの機能.2006

    • Author(s)
      佐藤 卓
    • Journal Title

      医学のあゆみ 別冊 消化器疾患states of arts I.消化管(食道・胃) 3

      Pages: 89-92

    • Data Source
      KAKENHI-PROJECT-18790332
  • [Journal Article] 樹状細胞のサイトカインを介する生体防御機構.2006

    • Author(s)
      佐藤 卓
    • Journal Title

      臨床免疫 45(2)

      Pages: 192-196

    • Data Source
      KAKENHI-PROJECT-18790332
  • [Presentation] Elucidation of transcriptional regulation mechanism of age-related microglia.2021

    • Author(s)
      Shun Isikawa, Taku Sato, Toshiaki Ohteki
    • Organizer
      The 27th International Symposium on Molecular Cell Biology of Macrophages.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02712
  • [Presentation] The 50th Annual Meeting of the Japanese Society for Immunology2021

    • Author(s)
      Shun Ishikawa Taku Sato Toshiaki Ohteki
    • Organizer
      Transcriptional mechanisms responsible for functional alteration of microglia in aging and Alzheimer's disease.
    • Data Source
      KAKENHI-PROJECT-21H02712
  • [Presentation] Identification of a key dermal immune cell population that disrupt epidermal homeostasis in autoimmune alopecia.2021

    • Author(s)
      Taku Sato, Toshiaki Ohteki.
    • Organizer
      The 27th International Symposium on Molecular Cell Biology of Macrophages.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02712
  • [Presentation] Regulated IFN-signal preserves stemness of intestinal stem-cells.2019

    • Author(s)
      Taku Sato, Toshiaki Ohteki.
    • Organizer
      The 14th International Symposium of the Institute Network for Biomedical Sciences
    • Data Source
      KAKENHI-PROJECT-18K07062
  • [Presentation] Regulated IFN-signal preserves stemness of intestinal stem-cells by restricting2018

    • Author(s)
      Taku Sato, Toshiaki Ohteki
    • Organizer
      第16回幹細胞シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07062
  • [Presentation] Combination effects of type-I IFNs and imatinib against Leukemia-initiating cells in mouse CML model.2012

    • Author(s)
      Taku Sato
    • Organizer
      2012 Annual Meeting of the Japanese Society of Immunology
    • Place of Presentation
      神戸
    • Year and Date
      2012-12-05
    • Data Source
      KAKENHI-PUBLICLY-23130505
  • [Presentation] Combination effects of type-I IFNs and imatinib against Leukemia-initiating cells in mouse CML model.2012

    • Author(s)
      Taku Sato
    • Organizer
      The 10th Stem Cell Research Symposium
    • Place of Presentation
      淡路島
    • Year and Date
      2012-05-31
    • Data Source
      KAKENHI-PUBLICLY-23130505
  • [Presentation] I型IFNの作用を利用した白血病幹細胞を標的とする白血病根治療法の創出2011

    • Author(s)
      佐藤卓
    • Organizer
      新学術領域研究「癌幹細胞を標的とする腫瘍根絶技術の新構築」第3回総括班会議
    • Place of Presentation
      福岡
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PUBLICLY-23130505
  • [Presentation] Novel interferon (IFN)-based pre-transplantation conditioning in the treatment of congenital metabolic disorder2011

    • Author(s)
      Taku Sato, Satoshi Yotsumoto, Toshiaki Ohteki
    • Organizer
      第40回日本免疫学会総会・学術集会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-23790326
  • [Presentation] IRF-2 protects haematopoietic stem cells from type-I interferon-dependent replicative exhaustion2008

    • Author(s)
      Sato, T.
    • Organizer
      第38日本免疫学会学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19590489
  • [Presentation] IRF-2 protects haematopoietic stem cells from type-I interferon-dependent renlicative exhaustion2008

    • Author(s)
      Sato, T.
    • Organizer
      第38日本免疫学会学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19041011
  • [Presentation] メモリーCD8T細胞の数的・機能的維持における樹状細胞の役割2007

    • Author(s)
      佐藤 卓
    • Organizer
      第17回Kyoto T Cell Conference (KTCC) 2007
    • Place of Presentation
      京都
    • Year and Date
      2007-06-16
    • Data Source
      KAKENHI-PROJECT-19590489
  • [Presentation] メモリーCD8T細胞の数的・機能的維持における樹状細胞の役割.2007

    • Author(s)
      佐藤卓
    • Organizer
      第17回Kyoto T Cell Conference
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19041011
  • [Presentation] Limited role of denderitic cells in the maintenance of memory CD8+T cells in lymphoreplete host.2007

    • Author(s)
      Sato, T.
    • Organizer
      第37回日本免疫学会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-22
    • Data Source
      KAKENHI-PROJECT-19041011
  • [Presentation] Limited role of denderitic cells in the maintenance of memory CD8^+ Tcells in lymphoreplete host.2007

    • Author(s)
      Sato, T.
    • Organizer
      第37回日本免疫学会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-22
    • Data Source
      KAKENHI-PROJECT-19590489
  • 1.  TADA Hiroyuki (70431632)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  ONAI N. Obuyuki (50323605)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  TEZUKA Hiroyuki (30375258)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  樗木 俊聡 (50233200)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  KAJITA Mihoko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  佐藤 俊朗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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