Sato Taku 佐藤卓

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Taku Sato 佐藤卓

SATO Taku 佐藤卓

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Researcher Number	40375259
Other IDs
Affiliation (Current)	2022: 東京医科歯科大学, 難治疾患研究所, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2022: 東京医科歯科大学, 難治疾患研究所, 准教授 2018 – 2019: 東京医科歯科大学, 難治疾患研究所, 講師 2013 – 2015: 東京医科歯科大学, 難治疾患研究所, 非常勤講師 2011 – 2012: 東京医科歯科大学, 難治疾患研究所, 特任助教 2008: 東北大学, 医学部, 教授 2007 – 2008: Akita University, 医学部, 助教 2006: 秋田大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Immunology / Basic Section 49030:Experimental pathology-related / Biological Sciences / General medical chemistry / Biological pharmacy / Medium-sized Section 50:Oncology and related fields Except Principal Investigator Biological Sciences
Keywords	Principal Investigator インターフェロン / 幹細胞性 / 組織幹細胞 / サイトカイン / 免疫学 / 細胞・組織 / 生体分子 / ウイルス / シダナル伝達 / シグナル伝達 … More / 抗原 / NOD1 / Cross-priming / dendritic cell / Cytotoxic T lymphocyte / Endotoxin shock / Nod1 / Dendritic cell / Cytotoxic T lymphocytes / 慢性骨髄性白血病 / 白血病幹細胞 / 細胞周期 / 造血幹細胞 / 表皮幹細胞 / 幹細胞 / 癌幹細胞 / 脳内炎症 / 炎症老化 / ミクログリア / 脳老化 / 遺伝子発現 / 全身老化 / 皮膚自己免疫疾患 / マクロファージ / 脂肪組織 / 間葉系幹細胞 / 皮膚エリテマトーデス / インタラクトーム / ヒトがんオルガノイド / 化学療法耐性 / がん幹細胞 / 自己分泌 / 治療抵抗性 / 腫瘍内癌不均一性 / ヒトがん … More Except Principal Investigator DC / poly I : C / I型IFN / NOD1 / NOD2 / クロスプライミング / 自然免疫 / TLR7 / TLR9 / TRAIL / DR5 / インフルエンザウィルス Less

Elucidation of the changes in tissue stem cell-niche interactions that cause skin autoimmune disordersPrincipal Investigator
- Principal Investigator
  
  佐藤卓
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Tokyo Medical and Dental University
ヒト癌オルガノイドオライブラリーを利用した治療抵抗性癌の発生・維持機構解明Principal Investigator
- Principal Investigator
  
  佐藤卓
- Project Period (FY)
  2021 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Tokyo Medical and Dental University
Effect of interferon signals in the brain on the induction of systemic agingPrincipal Investigator
- Principal Investigator
  
  Taku Sato
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Tokyo Medical and Dental University
Establishment of the eradication strategy for cancer stem cells by targeting IRF2Principal Investigator
- Principal Investigator
  
  Sato Taku
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Medical and Dental University
Ｉ型ＩＦＮの作用を利用した白血病幹細胞を標的とする白血病根治療法の創出Principal Investigator
- Principal Investigator
  
  佐藤卓
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Significance of the interferon signal regulation in the maintenance of tissue stem cellsPrincipal Investigator
- Principal Investigator
  
  SATO Taku
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Medical and Dental University
ウィルス抗原の提示における樹状細胞アポトーシスの免疫学的意義
- Principal Investigator
  
  樗木俊聡
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Akita University
Nod1-mediated regulation of immunological homeostasisPrincipal Investigator
- Principal Investigator
  
  SATO Taku, TADA Hiroyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Akita University
転写因子IRF-3による抗原特異的メモリーT細胞維持の分子機構Principal Investigator
- Principal Investigator
  
  佐藤卓
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Akita University

All 2021 2020 2019 2018 2013 2012 2011 2009 2008 2007 2006

All Journal Article Presentation

[Journal Article] 腸管上皮幹細胞におけるインターフェロンの役割2021
- Author(s)
  佐藤　卓, 樗木　俊聡
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 75 Pages: 759-764
- NAID
  40022604527
- Data Source
  KAKENHI-PROJECT-21H02712
[Journal Article] IRF2 maintains the stemness of colonic stem cells by limiting physiological stress from interferon.2020
- Author(s)
  Minamide K*, Sato T*, Nakanishi Y, Ohno H, Kato T, Asano J, Ohteki T. (*: equal contribution)
- Journal Title
  
  Sci Rep.
  
  Volume: 10 Pages: 14639-14639
- DOI
  10.1038/s41598-020-71633-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07062
[Journal Article] Regulated IFN signalling preserves the stemness of intestinal stem cells by restricting differentiation into secretory-cell lineages.2020
- Author(s)
  Sato T, Ishikawa S, Asano J, Yamamoto H, Fujii M, Sato T, Yamamoto K, Kitagaki K, Akashi T, Okamoto R, Ohteki T.
- Journal Title
  
  Nat Cell Biol.
  
  Volume: 22 Pages: 919-919
- DOI
  10.1038/s41556-020-0545-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06176, KAKENHI-PROJECT-20H03757, KAKENHI-PROJECT-18K07062
[Journal Article] Autophagy Detection in Intestinal Stem Cells.2020
- Author(s)
  Asano J*, Sato T*, Ohteki T. (*: equal contribution)
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 2171 Pages: 115-115
- DOI
  10.1007/978-1-0716-0747-3_7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07062
[Journal Article] Characterization of radioresistant epithelial stem cell heterogeneity in the damaged mouse intestine2020
- Author(s)
  Sato T, Sase M, Ishikawa S, Kajita M, Asano J, Sato T, Mori Y, and Ohteki T.
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Pages: 8308-8308
- DOI
  10.1038/s41598-020-64987-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H05028, KAKENHI-PROJECT-19H01024, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-19J40198, KAKENHI-PROJECT-18K07062, KAKENHI-PROJECT-18K07258
[Journal Article] Novel interferon-based pre-transplantation conditioning in the treatment of a congenital metabolic disorder.2013
- Author(s)
  Sato T, Ikeda M, Yotsumoto S, Shimada Y, Higuchi T, Kobayashi H, Fukuda T, Ohashi T, Suda T, Ohteki T.
- Journal Title
  
  Blood.
  
  Volume: 121 Pages: 3267-73
- Data Source
  KAKENHI-PROJECT-23790326
[Journal Article] Novel interferon-based pre-transplantation conditioning in the treatment of a congenital metabolic disorder.2013
- Author(s)
  Sato T(他9名)
- Journal Title
  
  Blood.
  
  Volume: 121 Pages: 3267-3273
- DOI
  10.1182/blood-2012-07-443713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23790326, KAKENHI-PROJECT-25460061
[Journal Article] IRF-2 protects quiescent HSCs from type-I interferondependent exhaustion2009
- Author(s)
  Sato, T., Onai, N., Yoshihara, H., Arai, F., Suda, T., and Ohteki, T.
- Journal Title
  
  Nat. Med. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590489
[Journal Article] IRF-2 protects quiescent HSCs from type-I interferon-dependent exhaustion2009
- Author(s)
  Sato, T.
- Journal Title
  
  Nature Medicine (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041011
[Journal Article] 消化管免疫24.生体防御におけるIELおよび腸管DCの機能.2006
- Author(s)
  佐藤卓
- Journal Title
  
  医学のあゆみ別冊消化器疾患states of arts I.消化管(食道・胃) 3
  
  Pages: 89-92
- Data Source
  KAKENHI-PROJECT-18790332
[Journal Article] 樹状細胞のサイトカインを介する生体防御機構.2006
- Author(s)
  佐藤卓
- Journal Title
  
  臨床免疫 45(2)
  
  Pages: 192-196
- Data Source
  KAKENHI-PROJECT-18790332
[Presentation] Elucidation of transcriptional regulation mechanism of age-related microglia.2021
- Author(s)
  Shun Isikawa, Taku Sato, Toshiaki Ohteki
- Organizer
  The 27th International Symposium on Molecular Cell Biology of Macrophages.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02712
[Presentation] The 50th Annual Meeting of the Japanese Society for Immunology2021
- Author(s)
  Shun Ishikawa Taku Sato Toshiaki Ohteki
- Organizer
  Transcriptional mechanisms responsible for functional alteration of microglia in aging and Alzheimer's disease.
- Data Source
  KAKENHI-PROJECT-21H02712
[Presentation] Identification of a key dermal immune cell population that disrupt epidermal homeostasis in autoimmune alopecia.2021
- Author(s)
  Taku Sato, Toshiaki Ohteki.
- Organizer
  The 27th International Symposium on Molecular Cell Biology of Macrophages.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02712
[Presentation] Regulated IFN-signal preserves stemness of intestinal stem-cells.2019
- Author(s)
  Taku Sato, Toshiaki Ohteki.
- Organizer
  The 14th International Symposium of the Institute Network for Biomedical Sciences
- Data Source
  KAKENHI-PROJECT-18K07062
[Presentation] Regulated IFN-signal preserves stemness of intestinal stem-cells by restricting2018
- Author(s)
  Taku Sato, Toshiaki Ohteki
- Organizer
  第16回幹細胞シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18K07062
[Presentation] Combination effects of type-I IFNs and imatinib against Leukemia-initiating cells in mouse CML model.2012
- Author(s)
  Taku Sato
- Organizer
  2012 Annual Meeting of the Japanese Society of Immunology
- Place of Presentation
  神戸
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PUBLICLY-23130505
[Presentation] Combination effects of type-I IFNs and imatinib against Leukemia-initiating cells in mouse CML model.2012
- Author(s)
  Taku Sato
- Organizer
  The 10th Stem Cell Research Symposium
- Place of Presentation
  淡路島
- Year and Date
  2012-05-31
- Data Source
  KAKENHI-PUBLICLY-23130505
[Presentation] I型IFNの作用を利用した白血病幹細胞を標的とする白血病根治療法の創出2011
- Author(s)
  佐藤卓
- Organizer
  新学術領域研究「癌幹細胞を標的とする腫瘍根絶技術の新構築」第3回総括班会議
- Place of Presentation
  福岡
- Year and Date
  2011-09-10
- Data Source
  KAKENHI-PUBLICLY-23130505
[Presentation] Novel interferon (IFN)-based pre-transplantation conditioning in the treatment of congenital metabolic disorder2011
- Author(s)
  Taku Sato, Satoshi Yotsumoto, Toshiaki Ohteki
- Organizer
  第40回日本免疫学会総会・学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23790326
[Presentation] IRF-2 protects haematopoietic stem cells from type-I interferon-dependent replicative exhaustion2008
- Author(s)
  Sato, T.
- Organizer
  第38日本免疫学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590489
[Presentation] IRF-2 protects haematopoietic stem cells from type-I interferon-dependent renlicative exhaustion2008
- Author(s)
  Sato, T.
- Organizer
  第38日本免疫学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19041011
[Presentation] メモリーCD8T細胞の数的・機能的維持における樹状細胞の役割2007
- Author(s)
  佐藤卓
- Organizer
  第17回Kyoto T Cell Conference (KTCC) 2007
- Place of Presentation
  京都
- Year and Date
  2007-06-16
- Data Source
  KAKENHI-PROJECT-19590489
[Presentation] メモリーCD8T細胞の数的・機能的維持における樹状細胞の役割.2007
- Author(s)
  佐藤卓
- Organizer
  第17回Kyoto T Cell Conference
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19041011
[Presentation] Limited role of denderitic cells in the maintenance of memory CD8+T cells in lymphoreplete host.2007
- Author(s)
  Sato, T.
- Organizer
  第37回日本免疫学会
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19041011
[Presentation] Limited role of denderitic cells in the maintenance of memory CD8^+ Tcells in lymphoreplete host.2007
- Author(s)
  Sato, T.
- Organizer
  第37回日本免疫学会
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19590489

1. TADA Hiroyuki (70431632)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. ONAI N. Obuyuki (50323605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. TEZUKA Hiroyuki (30375258)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 樗木俊聡 (50233200)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. KAJITA Mihoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 佐藤俊朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sato Taku 佐藤 卓

Taku Sato 佐藤 卓

SATO Taku 佐藤 卓

Research Projects

Research Products

Co-Researchers

Elucidation of the changes in tissue stem cell-niche interactions that cause skin autoimmune disordersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヒト癌オルガノイドオライブラリーを利用した治療抵抗性癌の発生・維持機構解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effect of interferon signals in the brain on the induction of systemic agingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of the eradication strategy for cancer stem cells by targeting IRF2Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Ｉ型ＩＦＮの作用を利用した白血病幹細胞を標的とする白血病根治療法の創出Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Significance of the interferon signal regulation in the maintenance of tissue stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ウィルス抗原の提示における樹状細胞アポトーシスの免疫学的意義

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Nod1-mediated regulation of immunological homeostasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

転写因子IRF-3による抗原特異的メモリーT細胞維持の分子機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 腸管上皮幹細胞におけるインターフェロンの役割2021

Author(s)

Journal Title

NAID

Data Source

[Journal Article] IRF2 maintains the stemness of colonic stem cells by limiting physiological stress from interferon.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulated IFN signalling preserves the stemness of intestinal stem cells by restricting differentiation into secretory-cell lineages.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Autophagy Detection in Intestinal Stem Cells.2020

Author(s)

Journal Title

DOI

Data Source

Sato Taku 佐藤卓

Taku Sato 佐藤卓

SATO Taku 佐藤卓