Horie Shintaro 堀江真太郎

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HORIE Shintarou 堀江真太郎

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Researcher Number	40376744
Other IDs
Affiliation (Current)	2025: 東京科学大学, 大学院医歯学総合研究科, 講師
Affiliation (based on the past Project Information) *help	2015 – 2016: 東京医科歯科大学, 医学部附属病院, 助教 2014: 東京医科歯科大学, 医歯(薬)学総合研究科, 助教 2010: Tokyo Medical and Dental University, 医学部附属病院, 医員 2009: Tokyo Medical and Dental University, 医学部・附属病院, 医員
Review Section/Research Field	Principal Investigator Ophthalmology
Keywords	Principal Investigator 眼内環境 / 糖尿病網膜症 / 網膜色素上皮細胞 / マクロファージ / ミエロイド細胞 / ヒト細胞 / 活性化T細胞抑制 / 眼色素上皮細胞 / 細胞治療 / 制御性T細胞 / 眼炎症

Research Projects
(2 results)
Research Products
(22 results)

Acquired phenotype of myeloid cells under retinal pigment epithelium mediated ocular conditionPrincipal Investigator
- Principal Investigator
  
  Horie Shintaro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Tokyo Medical and Dental University
The regulatory phenotype in human PE-induced Treg cellsPrincipal Investigator
- Principal Investigator
  
  HORIE Shintarou
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Tokyo Medical and Dental University

All 2016 2015 2010 2009

All Journal Article Presentation

[Journal Article] 最近の糖尿病黄斑浮腫の診療2016
- Author(s)
  堀江真太郎、大野京子
- Journal Title
  
  週刊日本医事新報
  
  Volume: 4786 Pages: 54-54
- Data Source
  KAKENHI-PROJECT-26861438
[Journal Article] Bilateral hearing impairment as the initial symptom of sympathetic ophthalmia2015
- Author(s)
  Yoshiyuki Kawashima, Yoshihiro Noguchi,Hiroshi Takase,Masatoki Takahashi, Shintaro Horie
- Journal Title
  
  American Journal of Otolaryngology
  
  Volume: In Press Issue: 4 Pages: 606-610
- DOI
  10.1016/j.amjoto.2015.02.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26861438, KAKENHI-PROJECT-25462630
[Journal Article] Suppression of bystander T helper 1 cells by iris pigment epithelium-inducing regulatory T cells via negative costimulatory signals2010
- Author(s)
  Sugita S, Horie S, et al
- Journal Title
  
  Investigative Opthalmology and Visual Sciences
  
  Volume: 51 Pages: 2529-2536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791672
[Journal Article] Human retinal pigment epithelium-inducded CD4+CD25+regulatory T cells suppress activation of intraocular effector T cells2010
- Author(s)
  Horie S, et al
- Journal Title
  
  Clinical Immunology
  
  Volume: 136 Pages: 83-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791672
[Journal Article] Inhibition of B-Cell Activation by Retinal Pigment Epithelium.2010
- Author(s)
  Sugita S, Horie S, et al.
- Journal Title
  
  Invest Ophthalmol Vis Sci vol.51(11)
  
  Pages: 5783-5788
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791672
[Journal Article] Inhibition of B-cell activation by retinal pigment epithelium2010
- Author(s)
  Sugita S, Horie S, et al
- Journal Title
  
  Investigative Opthalmology and Visual Sciences
  
  Volume: 51 Pages: 5783-5788
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791672
[Journal Article] Suppression of bystander T helper 1 cells by iris pigment epithelium-inducing regulatory T cells via negative costimulatory signals.2010
- Author(s)
  Sugita S, Horie S, et al.
- Journal Title
  
  Invest Ophthalmol Vis Sci vol.51(5)
  
  Pages: 2529-2536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791672
[Journal Article] Human retinal pigment epithelium-inducded CD4+CD25+regulatory T cells suppress activation of intraocular effector T cells.2010
- Author(s)
  Horie S, Sugita S, et al.
- Journal Title
  
  Clinical Immunology vol.136(1)
  
  Pages: 83-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791672
[Journal Article] Mechanisms of immune suppression for CD8+ T cells by human corneal endothelial cells via membrane-bound TGFbeta.2010
- Author(s)
  Yamada Y, Sugita S, Horie S, et al.
- Journal Title
  
  Invest Ophthalmol Vis Sci vol.51(5)
  
  Pages: 2548-2557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791672
[Journal Article] Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye derived CTLA-2 alpha during inflammatory conditions2009
- Author(s)
  Sugita S, Horie S, et al.
- Journal Title
  
  Journal of Immunology 183
  
  Pages: 5013-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791672
[Journal Article] Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye-derived CTLA-2alpha during inflammatory conditions.2009
- Author(s)
  Sugita S, Horie S, et al.
- Journal Title
  
  J Immunol vol.183(8)
  
  Pages: 5013-5022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791672
[Journal Article] Human iris pigment epithelium suppress activation of bystandar T cells via TGF beta-TGF beta receptor interaction2009
- Author(s)
  Horie S, et al.
- Journal Title
  
  Experimental Eye Research 88
  
  Pages: 1033-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791672
[Journal Article] Iris pigment epithelium-inducing regulatory T cells suppress bystander T helper1 cells via negative costimulatory signals2009
- Author(s)
  Sugita S, Horie S, et al.
- Journal Title
  
  Investigative Opthalmology and Visual Sciences (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791672
[Journal Article] Human iris pigment epithelium suppresses activation of bystander T cells via TGFbeta-TGFbeta receptor interaction.2009
- Author(s)
  Horie S, Sugita S, et al.
- Journal Title
  
  Exp Eye Res vol.88(6)
  
  Pages: 1033-1042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791672
[Presentation] Evaluation of En-face OCT Images in Diabetic Macular Edema with Anti-VEGF Treatment2016
- Author(s)
  Shintaro Horie, Mitsunao Ide, Kei Morohoshi, Kyoko Ohno-Matsui
- Organizer
  ARVO2016(国際学会）
- Place of Presentation
  シアトル（米国）
- Year and Date
  2016-05-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861438
[Presentation] 糖尿病黄斑浮腫の抗VEGF治療におけるEn face OCTの有用性の比較検討2016
- Author(s)
  井出光直、堀江真太郎、諸星計、大野京子
- Organizer
  第１２０回日本眼科学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-04-08
- Data Source
  KAKENHI-PROJECT-26861438
[Presentation] Character of PMA-Stimulated THP-1 Cells under Ocular Diabetic Condition2015
- Author(s)
  Shintaro Horie
- Organizer
  ARVO2015
- Place of Presentation
  Denver (Colorado USA)
- Year and Date
  2015-05-05
- Data Source
  KAKENHI-PROJECT-26861438
[Presentation] Character of PMA-Stimulated THP-1 Cells under Ocular Diabetic Condition2015
- Author(s)
  Shintaro Horie, Koju Kamoi, Zaorong Guo, Kyoko Ohno-Matsui
- Organizer
  ARVO2015
- Place of Presentation
  デンバー（米国）
- Year and Date
  2015-05-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861438
[Presentation] Potential Effects of Toll-Like Receptor 4 Signaling on RPE Dedifferentiation by TGFb2010
- Author(s)
  Horie S, et al
- Organizer
  ARVO
- Place of Presentation
  Fort Lauderdale (Fl, USA)
- Year and Date
  2010-05-05
- Data Source
  KAKENHI-PROJECT-21791672
[Presentation] Potential Effects of Toll-Like Receptor 4 Signaling on RPE Dedifferentiation by TGFb.2010
- Author(s)
  Horie S, et al.
- Organizer
  ARVO
- Place of Presentation
  Fort Lauderdale (Fl, USA)
- Year and Date
  2010-05-05
- Data Source
  KAKENHI-PROJECT-21791672
[Presentation] Human retinal pigment epithelium-induced CD4^+CD25^+ regulatory T cells suppress activation of intraocular effector T cells2009
- Author(s)
  Horie S, et al.
- Organizer
  10th International Ocular Inflammation Society
- Place of Presentation
  Prague(Czech)
- Year and Date
  2009-05-30
- Data Source
  KAKENHI-PROJECT-21791672
[Presentation] Human retinal pigment epithelium-induced CD4^+CD25^+ regulatory T cells suppress activation of intraocular effector T cells.2009
- Author(s)
  Horie S, et al.
- Organizer
  10th International Ocular Inflammation Society.
- Place of Presentation
  Prague (Czech)
- Year and Date
  2009-05-30
- Data Source
  KAKENHI-PROJECT-21791672

Horie Shintaro 堀江 真太郎

HORIE Shintarou 堀江 真太郎

Research Projects

Research Products

Acquired phenotype of myeloid cells under retinal pigment epithelium mediated ocular conditionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The regulatory phenotype in human PE-induced Treg cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 最近の糖尿病黄斑浮腫の診療2016

Author(s)

Journal Title

Data Source

[Journal Article] Bilateral hearing impairment as the initial symptom of sympathetic ophthalmia2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Suppression of bystander T helper 1 cells by iris pigment epithelium-inducing regulatory T cells via negative costimulatory signals2010

Author(s)

Journal Title

Data Source

[Journal Article] Human retinal pigment epithelium-inducded CD4+CD25+regulatory T cells suppress activation of intraocular effector T cells2010

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of B-Cell Activation by Retinal Pigment Epithelium.2010

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of B-cell activation by retinal pigment epithelium2010

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of bystander T helper 1 cells by iris pigment epithelium-inducing regulatory T cells via negative costimulatory signals.2010

Author(s)

Journal Title

Data Source

[Journal Article] Human retinal pigment epithelium-inducded CD4+CD25+regulatory T cells suppress activation of intraocular effector T cells.2010

Author(s)

Journal Title

Data Source

[Journal Article] Mechanisms of immune suppression for CD8+ T cells by human corneal endothelial cells via membrane-bound TGFbeta.2010

Author(s)

Journal Title

Data Source

[Journal Article] Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye derived CTLA-2 alpha during inflammatory conditions2009

Author(s)

Journal Title

Data Source

[Journal Article] Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye-derived CTLA-2alpha during inflammatory conditions.2009

Author(s)

Journal Title

Data Source

[Journal Article] Human iris pigment epithelium suppress activation of bystandar T cells via TGF beta-TGF beta receptor interaction2009

Author(s)

Journal Title

Data Source

[Journal Article] Iris pigment epithelium-inducing regulatory T cells suppress bystander T helper1 cells via negative costimulatory signals2009

Author(s)

Journal Title

Data Source

[Journal Article] Human iris pigment epithelium suppresses activation of bystander T cells via TGFbeta-TGFbeta receptor interaction.2009

Author(s)

Journal Title

Data Source

[Presentation] Evaluation of En-face OCT Images in Diabetic Macular Edema with Anti-VEGF Treatment2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 糖尿病黄斑浮腫の抗VEGF治療におけるEn face OCTの有用性の比較検討2016

Horie Shintaro 堀江真太郎

HORIE Shintarou 堀江真太郎