obata koji 小畑孝二

… Alternative Names

Obata Koji 小畑孝二

OBATA Koji 小畑孝二

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Researcher Number	40378229
Other IDs
Affiliation (Current)	2025: 岐阜医療科学大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 岐阜医療科学大学, 薬学部, 准教授 2018 – 2019: 岐阜大学, 大学院医学系研究科, 助教 2012 – 2015: 岐阜大学, 医学(系)研究科(研究院), 助教 2012: 岐阜大学, 医学系研究科, 助教 2009 – 2011: Aichi Gakuin University, 医学部, 助教 … More 2010: 愛知学院大学, 歯学部, 助教 2007 – 2008: Aichi Gakuin University, School of Dentistry, Associate Professor 2006: 愛知学院大学, 歯学部, 助手 2005: 名古屋大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / General physiology / Functional basic dentistry / Experimental pathology Except Principal Investigator Functional basic dentistry / Biological Sciences / Hygiene / Rehabilitation science/Welfare engineering
Keywords	Principal Investigator 筋収縮 / エネルギー代謝 / 酸素消費 / 心臓 / エネルギー消費 / カルシウム / 心機能 / 心不全 / 収縮性 / 興奮収縮連関 … More / カルシウムイメージング / カルシニューリン / 食品成分 / 栄養 / カルシウムハンドリング / 基礎代謝 / 拡張能 / 脂肪酸 / メタボローム / 収縮 / メタボローム解析 / 収縮効率 / エネルギー効率 / 糖尿病 / 高血圧 / 脂質代謝 / 心収縮 / 遺伝子組換え / カルシウムトランジェント / 総機械的エネルギー / G-CaMP / GECIs / イメージング / カルシウムイオン / 心筋細胞 / 遺伝子組換え型蛍光カルシウムプローブ / トランスジェニックラット / 筋小胞体 / 心臓力学 / 可溶性RANKL / 遺伝子導入 / siRNA / RAW264.7 / NFAT / RCAN1 / RCAN / 骨吸収 / 破骨細胞 / シグナル伝達 / 骨代謝 / アンジヲテンシンII / 遺伝子組換えマウス / 内因性カルシニューリン抑制因子 / アンギオテンシンII / ZAKI-4β / 心筋線維化 / 心肥大 / 遺伝子組み換えマウス … More Except Principal Investigator 骨芽細胞 / 心筋梗塞 / カルシウムイオン / 神経 / 感覚神経 / 骨代謝 / 交感神経 / 連鎖解析 / 罹患同胞対 / Synapse / Scorpion venom / Calcium ion / Co-culture / Nerve / Osteoblast / calphostin C / p-ERK / PKA / cAMP / ヒト骨芽細胞 / フォルスコリン / RAW264.7 / RANKL / CGRP / 破骨細胞 / イソプレナリン / 細胞内カルシウム / 神経細胞 / シナプス / サソリ毒 / 共培養 / DNA Bank / Susceptibility Gene / Odds Ratio / Genome-Wide and Candidate Gene Association Study / Lifestyle Related-Disease / Cohort Study / King Study / Investigation of Genetic Risk of Cardiovascular Di / 症例-対照関連解 / KING study / DNAバンク / 疾患感受性遺伝子 / 遺伝子型頻度 / 症例-対照関連解析 / 生活習慣病 / コホート研究 / KING Study / 北名古屋ゲノム疫学研究 / サテライト細胞 / 伝達 / メカニカルストレス / 細胞 / 肝細胞増殖因子 / 自然発症高血圧ラット / グルココルチコイド / アドレナリン / 時計遺伝子 / 染色体連鎖領域 / 2番染色体連鎖領域 / 高密度SNPタイピング / 染色体連鎖解析 / マイクロサテライトマーカー / マイクロサテライト解析 / 大規模関連解析 / ポジショナル候補遺伝子アプローチ / ゲノム / 遺伝子 Less

Development of therapeutic agents for heart failure by altering energy metabolism using cardiac mechanoenergetics analysisPrincipal Investigator
- Principal Investigator
  
  小畑孝二
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Gihu University of Medical Science
Development of heart failure therapy by altering cardiac energy metabolismPrincipal Investigator
- Principal Investigator
  
  Obata Koji
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Gihu University of Medical Science
  Gifu University
Development of whole heart calcium imaging system with two different waves using modified G-CaMP-DsRed-coexpressed transgenic rat model in the blood-perfused excised heart preparationPrincipal Investigator
- Principal Investigator
  
  Obata Koji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Gifu University
The role of the sympathetic nervous system in physiologicalresponse to mechanical stress
- Principal Investigator
  
  ASADA Keiji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Suzuka University of Medical Science
Establishment of simultaneous real-time measurement system for myocardial mechanenergetics and calcium dynamics in rat whole hearts.Principal Investigator
- Principal Investigator
  
  OBATA Koji
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Nara Medical University
Pharmacological study on circadian gene expression induced by sympathetic nervous activity in osteoblastic cells.
- Principal Investigator
  
  TOGARI Akifumi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Aichi Gakuin University
Role of regulators of calcineurin 1, RCAN1 as an endogenous calcineur in inhibitor, on osteoolast differentiationPrincipal Investigator
- Principal Investigator
  
  OBATA Koji
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Aichi Gakuin University
全ゲノム罹患同胞対連鎖解析及び候補遺伝子関連解析による心筋梗塞感受性遺伝子の同定
- Principal Investigator
  
  横田充弘
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Aichi Gakuin University
内因性カルシニューリン抑制蛋白質ZAKI-4βの心筋肥大化制御分子としての役割Principal Investigator
- Principal Investigator
  
  小畑孝二
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Aichi Gakuin University
罹患同胞対連鎖解析及び候補遺伝子間連解析による心筋梗塞感受性遺伝子の同定
- Principal Investigator
  
  YOKOTA Mitsuhiro
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Population based study of genetic risk and gene-environment interaction in lifestyle-related diseases including coronary artery diseases(KING Study)
- Principal Investigator
  
  YOKOTA Mitsuhiro
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hygiene
- Research Institution
  Aichi Gakuin University
  Nagoya University
Pharmacological study on bone metabolism by nervous activity
- Principal Investigator
  
  TOGARI Akifumi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Aichi Gakuin University

[Journal Article] 心臓病治療薬開発に向けた左心室メカノエナジェティクス解析の重要性2022
- Author(s)
  小畑孝二
- Journal Title
  
  Precision Medicine誌
  
  Volume: 5 Pages: 87-89
- Data Source
  KAKENHI-PROJECT-18K11125
[Journal Article] 心臓病治療に向けた左心室メカノエナジェティクス解析による収縮効率の重要性2021
- Author(s)
  小畑孝二、高木　都
- Journal Title
  
  Medical Science Digest
  
  Volume: 47(1) Pages: 40-42
- Data Source
  KAKENHI-PROJECT-18K11125
[Journal Article] 左心室メカノエナジェティクス解析による心臓病治療に向けた収縮効率の重要性2020
- Author(s)
  小畑孝二、高木　都
- Journal Title
  
  BIO Clinica
  
  Volume: 35(9) Pages: 59-62
- Data Source
  KAKENHI-PROJECT-18K11125
[Journal Article] Mechanism underlying the negative inotropic effect in rat left ventricle in hyperthermia: the role of TRPV12020
- Author(s)
  Obata Koji、Morita Hironobu、Takaki Miyako
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 70 Issue: 1 Pages: 4-4
- DOI
  10.1186/s12576-020-00734-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11125, KAKENHI-PROJECT-18K06850
[Journal Article] The energy-saving effect of a new myosin activator, omecamtiv mecarbil, on LV mechanoenergetics in rat hearts with blood-perfused isovolumic contraction model2019
- Author(s)
  Obata Koji、Morita Hironobu、Takaki Miyako
- Journal Title
  
  Naunyn-Schmiedeberg's Archives of Pharmacology
  
  Volume: 392 Issue: 9 Pages: 1065-1070
- DOI
  10.1007/s00210-019-01685-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11125
[Journal Article] Left ventricular mechanoenergetics in excised, cross-circulated rat hearts under hypo-, normo-, and hyperthermic conditions2018
- Author(s)
  Obata Koji、Takeshita Daisuke、Morita Hironobu、Takaki Miyako
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 16246-16246
- DOI
  10.1038/s41598-018-34666-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11125
[Journal Article] Methods for the Preparation of an Excised, Cross-Circulated Rat Heart2018
- Author(s)
  Obata Koji、Takaki Miyako
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1816 Pages: 117-132
- DOI
  10.1007/978-1-4939-8597-5_9
- ISBN
  9781493985968, 9781493985975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K11125
[Journal Article] Feasibility of a short-arm centrifuge for mouse hypergravity experiments2015
- Author(s)
  Morita H, et al.
- Journal Title
  
  PLOS ONE
  
  Volume: 10(7): e133981 Issue: 7 Pages: 1-14
- DOI
  10.1371/journal.pone.0133981
- NAID
  120007136296
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K11916, KAKENHI-INTERNATIONAL-15K21745, KAKENHI-ORGANIZER-15H05935, KAKENHI-PLANNED-15H05940, KAKENHI-PROJECT-25460283
[Journal Article] Hypergravity provokes a temporary reduction in CD4+CD8+ thymocyte number and a persistent decrease in medullary thymic epithelial cell frequency in mice.2015
- Author(s)
  Tateishi R, Akiyama N, Miyauchi M, Yoshinaga R, Sasanuma H, Kudo T, Shimbo M, Shinohara M, Obata K, Inoue J, Shirakawa M, Shiba D, Asahara H, Yoshida N, Takahashi S, Morita H, Akiyama T
- Journal Title
  
  PLOS ONE
  
  Volume: 10 Issue: 10 Pages: 1-17
- DOI
  10.1371/journal.pone.0141650
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15540, KAKENHI-INTERNATIONAL-15K21745, KAKENHI-PUBLICLY-15H01150, KAKENHI-PUBLICLY-15H01176, KAKENHI-ORGANIZER-15H05935, KAKENHI-PLANNED-15H05940, KAKENHI-PROJECT-25460283, KAKENHI-PROJECT-26670234, KAKENHI-PROJECT-26290036
[Journal Article] Persistent overexpression of SERCA2a affects bladder functionsunder physiological conditions, but not in bladder outlet obstruction-induced sub-acute pathological conditions.2014
- Author(s)
  Yamada A, Torimoto K, Obata K, Hirayama A, Fujimoto K, Takaki M
- Journal Title
  
  J Physiol Sci
  
  Volume: 64 Issue: 1 Pages: 21-30
- DOI
  10.1007/s12576-013-0286-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390330, KAKENHI-PROJECT-25460283
[Journal Article] Possible peripheral mechanism for taste disorder in S-1 administered rats.2014
- Author(s)
  Aoki K, Obata K, Kurihara M, Kuniyasu H, Kirita T, Takaki M
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 19 Issue: 3 Pages: 549-556
- DOI
  10.1007/s10147-013-0572-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390330, KAKENHI-PROJECT-25460283, KAKENHI-PROJECT-25670177, KAKENHI-PROJECT-25861968
[Journal Article] A new calpain inhibitor protects left ventricular dysfunction induced by mild ischemia-reperfusion in in situ rat hearts.2013
- Author(s)
  Takeshita D, Obata K, Takak M, 他6名
- Journal Title
  
  JPhysiol Sci
  
  Volume: 63 Issue: 2 Pages: 113-123
- DOI
  10.1007/s12576-012-0243-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500487, KAKENHI-PROJECT-22500489, KAKENHI-PROJECT-23592046, KAKENHI-PROJECT-25460283
[Journal Article] In vivo imaging of enteric neurogenesis in the deep tissue of mouse smallintestine. hearts of SERCA2a transgenic rats.2013
- Author(s)
  Goto K, Obata K, Takaki M, 他
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 1 Pages: e54814-e54814
- DOI
  10.1371/journal.pone.0054814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500487, KAKENHI-PROJECT-23591969, KAKENHI-PROJECT-23700480, KAKENHI-PROJECT-24650325, KAKENHI-PROJECT-25350645, KAKENHI-PROJECT-25460283, KAKENHI-PROJECT-25670177
[Journal Article] Left ventricular mechanical and energetic changes in long-term isoproterenol-induced hypertrophied.2013
- Author(s)
  Mitsuyama S, Obata K, Takaki M, 他2名
- Journal Title
  
  J Mol Cell Cardiol.
  
  Volume: 59 Pages: 95-106
- DOI
  10.1016/j.yjmcc.2013.02.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500487, KAKENHI-PROJECT-25460283
[Journal Article] Evaluation of left ventricular mechanical work and energetics of normal hearts in SERCA2a transgenic rats.2012
- Author(s)
  Zhang GX, Obata K, Takaki M, 他8名
- Journal Title
  
  J Physiol Sci
  
  Volume: 62 Issue: 3 Pages: 221-231
- DOI
  10.1007/s12576-012-0200-4
- NAID
  10030742386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500487, KAKENHI-PROJECT-22650068, KAKENHI-PROJECT-22790216
[Journal Article] NHE-1 blockade reversed changes in calcium transient in myocardial slices from isoproterenol-induced hypertrophied rat left ventricle2012
- Author(s)
  Hattori H, Obata K, Takaki M, 他
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 419 Issue: 2 Pages: 431-435
- DOI
  10.1016/j.bbrc.2012.02.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500487, KAKENHI-PROJECT-22790211, KAKENHI-PROJECT-22790216, KAKENHI-PROJECT-23390042, KAKENHI-PROJECT-23650258, KAKENHI-PROJECT-23689011
[Journal Article] Comparison of effects of a selective 5-HT reuptake inhibitor versus a 5-HT4 receptor agonist on in vivo neurogenesis at the rectal anasotomosis in rats.2012
- Author(s)
  Kawahara I. Obata K, Takaki M
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 302 Issue: 6 Pages: 588-597
- DOI
  10.1152/ajpgi.00284.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500487, KAKENHI-PROJECT-22591491, KAKENHI-PROJECT-22790216, KAKENHI-PROJECT-23390330, KAKENHI-PROJECT-23591969, KAKENHI-PROJECT-24650325
[Journal Article] Age-related changes in afferent responses in sensory neurons to mechanical stimulation of osteoblasts in coculture system2012
- Author(s)
  Asada K, Obata K, Horiguchi K, Takaki M
- Journal Title
  
  Am J Physiol Cell Physiol
  
  Volume: 302 Issue: 5 Pages: 757-765
- DOI
  10.1152/ajpcell.00362.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500487
[Journal Article] Invitro enhanced differentiation of neural networksin ES gut-like organ from mouse ES cells by a 5-HT4-receptor activation.2011
- Author(s)
  Takaki M, Misawa H, Matsuyoshi H, Kawahara I,Goto K, Zhang GX, Obata K, Kuniyasu H
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 406 Issue: 4 Pages: 529-533
- DOI
  10.1016/j.bbrc.2011.02.072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500487, KAKENHI-PROJECT-22790216, KAKENHI-PROJECT-23591969
[Journal Article] In vitro enhanced differentiation of neural networks in ES gut-like organ from mouse ES cells by a 5-HT4-receptor activation.2011
- Author(s)
  Takaki M, Misawa H, Matsuyoshi H, Kawahara, I GotoK, Zhang GX, Obata K, Kuniyasu H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 406 Pages: 529-533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500487
[Journal Article] NHE-1 participates in isoproterenol-induced down-regulation of SERCA2a and development of cardiac remodeling in rat hearts2011
- Author(s)
  Shibata M, Obata K, Takaki M, 他
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: 301 Issue: 5 Pages: 2154-2160
- DOI
  10.1152/ajpheart.00483.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500487, KAKENHI-PROJECT-22790216
[Journal Article] Effects of Angiotensin Type I Receptor Blockade on the Cardiac Raf/MEK/ERK Cascade Activated via Adrenergic Receptors2010
- Author(s)
  Zhang GX, Kimura S, Murao K, Yu X, Obata K, Matsuyoshi H, Takaki M
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 113 Issue: 3 Pages: 224-233
- DOI
  10.1254/jphs.09336FP
- NAID
  10029889243
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790216
[Journal Article] Inhibition of cytochrome c release by 10-N-nonyl acridine orange, a cardiolipin-specific dye, during myocardial ischemia-reperfusion in the rat2010
- Author(s)
  Zhang GX, Kimura S, Murao K, Obata K, Matsuyoshi H, Takaki M
- Journal Title
  
  Am J Physiol Heart Circ Physiol 298(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791366
[Journal Article] A cardioprotective agent of a novel calpain inhibitor, SNJ- 1945 exerts beta1-actions on left ventricular mechanical work and energetics.2010
- Author(s)
  Yoshiro Yoshikawa, Guo-Xing Zhang, Koji Obata, Hiroko Matsuyoshi, Keiji Asada, Shigeki Taniguchi, Miyako Takaki
- Journal Title
  
  Am J Physiol Heart Physiol
  
  Volume: 299 Pages: 396-401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500487
[Journal Article] A cardioprotective agent of a novel calpain inhibitor,SNJ- 1945 exerts beta1-actions on left ventricular mechanical work and energetics.2010
- Author(s)
  Yoshikawa Y, Obata K, Asada K, Takaki M, 他
- Journal Title
  
  Am J Physiol Heart Physiol.
  
  Volume: 299 Issue: 2 Pages: 396-401
- DOI
  10.1152/ajpheart.00153.2010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500487, KAKENHI-PROJECT-22790216
[Journal Article] Cardioprotective effects of a novel calpain inhibitor SNJ-1945 for reperfusion injury after cardioplegic cardiac arrest2010
- Author(s)
  Yoshikawa Y, Zhang GX, Obata K, Ohga Y, Matsuyoshi H, Taniguchi S, Takaki M
- Journal Title
  
  Am J Physiol Heart Circ Physiol 298(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791366
[Journal Article] A 5-HT(4)-receptor activation-induced neural plasticity enhances in vivo reconstructs of enteric nerve circuit insult2010
- Author(s)
  Matsuyoshi H, Kuniyasu H, Okumura M, Misawa H, Katsui R, Zhang GX, Obata K, Takaki M
- Journal Title
  
  Neurogastroenterol Motil (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791366
[Journal Article] Changes in contractile and electrical activity in the ileum of DSS-induced colitis model W/Wv mutant mice2010
- Author(s)
  Matsuyoshi H, Nakagawa T, Zhang GX, Obata K, Misawa H, Kawahara I, Takaki M
- Journal Title
  
  Journal of Smooth Muscle Research
  
  Volume: 46 Issue: 3 Pages: 143-156
- DOI
  10.1540/jsmr.46.143
- NAID
  130000860969
- ISSN
  0916-8737, 1884-8796
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790216
[Journal Article] Mechanism of diastolic stiffening of the failing myocardium and its prevention by angiotensin receptor and calcium channel blockers2009
- Author(s)
  Cheng XW, Okumura K, Kuzuya M, Jin Z, Nagata K, Obata K, Inoue A, Hirashiki A, Takeshita K, Unno K, Harada K, Shi GP, Yokota M, Murohara T
- Journal Title
  
  J Cardiovasc Pharmacol
  
  Pages: 47-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791366
[Journal Article] Left ventricular function of isoproterenol-induced hypertrophied rat hearts perfused with blood: mechanical work and energetics2009
- Author(s)
  Nakajima-Takenaka C, Zhang GX, Obata K, Tohne K, Matsuyoshi H, Nagai Y, Nishiyama A, Takaki M
- Journal Title
  
  Am J Physiol Heart Circ Physiol 297(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791366
[Journal Article] Long-term administration of nifedipine attenuates cardiac remodeling and diastolic heart failure in hypertensive rats2009
- Author(s)
  Yamada T, Nagata K, Cheng XW, Obata K, Saka M, Miyachi M, Naruse K, Nishizawa T, Noda A, Izawa H, Kuzuya M, Okumura K, Murohara T Yokota M
- Journal Title
  
  Eur J Pharmacol 615(1-3)
  
  Pages: 163-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791366
[Journal Article] Dobutamine stress testing as a diagnostic tool for evaluation of myocardial contractile reserve in asymptomatic or mildly symptomatic patients with dilated cardiomyopathy2008
- Author(s)
  Kobayashi M, Izawa H, Cheng XW, Asano H, Hirashiki A, Unno K, Ohshima S, Yamada T, Murate Y, Kato TS, Obata K, Noda A, Nishizawa T, lsobe S, Nagata K, Matsubara T, Murohara T, Yokota M
- Journal Title
  
  JACC Cardiovasc Imaging 1
  
  Pages: 718-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791366
[Journal Article] Superoxide-dependent cathepsin activation is associated with hypertensive myocardial remodeling and represents a target for angiotensin II type 1 receptor blocker treatment2008
- Author(s)
  Cheng XW, Murohara T, Kuzuya M, Izawa H, Sasaki T, Obata K, Nagata K, Nishizawa T, Kobayashi M, Yamada T, Kim W, Sato K, Shi GP, Okumura K, Yokota M
- Journal Title
  
  Am J Pathol 173(2)
  
  Pages: 358-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791366
[Journal Article] Xanthine oxidase inhibition improves left ventricular dysfunction in dilated cardiomyopathic hamsters2008
- Author(s)
  Hayashi K, Kimata H, Obata K, Matsushita A, Fukata A, Hashimoto K, Noda A, Iwase M, Koike Y, Yokota M, Nagata K
- Journal Title
  
  J Card Fail 14(3)
  
  Pages: 238-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791366
[Journal Article] Pioglitazone attenuates cardiac hypertrophy in rats with salt-sensitive hypertension: role of activation of AMP-activated protein kinase and inhibition of Akt2008
- Author(s)
  Kato MF, Shibata R, Obata K, Miyachi M, Yazawa H, Tsuboi K, Yamada T, Nishizawa T, Nada A, Cheng XW, Murate T, Koike Y, Murohara T, Yokota M, Nagata K
- Journal Title
  
  J Hypertens 26(8)
  
  Pages: 1669-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791366
[Journal Article] 骨関連細胞と神経細胞の共培養実験法の確立と細胞間相互作用の検討2008
- Author(s)
  小畑孝二, 戸苅彰史
- Journal Title
  
  口腔組織培養学会誌 17:
  
  Pages: 15-25
- Data Source
  KAKENHI-PROJECT-20791366
[Journal Article] Direct neurite-osteoblastic cell communication, as demonstrated by use of an in vitro co-culture system.2007
- Author(s)
  Obata, K., Furuno, T., Nakashini, M., Togari, A.
- Journal Title
  
  FEBS Letters 58
  
  Pages: 5917-5922
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Journal Article] Direct neurite-osteoblastic cell communication, as demonstrated by use of an in vitro co-culture system.2007
- Author(s)
  Obata, K., Furuno, T., Nakashini, M., Togari, A.
- Journal Title
  
  FEBS Letters 581
  
  Pages: 5917-5922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591956
[Journal Article] Direct neurite-osteoblastic cell communication,as demonstrated by use of an in vitro co-culture system2007
- Author(s)
  Obata, K., Furuno, T., Nakashini, M., Togari, A.
- Journal Title
  
  FEBS Letters 581
  
  Pages: 5917-5922
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591956
[Journal Article] Overexpression of calmodulin induces cardiac hypertrophy by a calcineurin-dependent pathway.2005
- Author(s)
  Koji Obata
- Journal Title
  
  Biochemical and Biophysical Research Communications 338
  
  Pages: 1299-1305
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209021
[Journal Article] Overexpression of calmodulin induces cardiac hypertrophy by a calcineurin-dependent pathway2005
- Author(s)
  Koji Obata
- Journal Title
  
  Biochemical and Biophysical Research Communications 338
  
  Pages: 1299-1305
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209021
[Journal Article] Overexpression of calmodulin induces cardiac hypertrophy by a calcineurin-dependent pathway.2005
- Author(s)
  Koji Obata
- Journal Title
  
  Biochemical and Biophysical Research Communications 338
  
  Pages: 1299-1305
- Data Source
  KAKENHI-PROJECT-17019028
[Presentation] ラット摘出心臓の血液交叉灌流実験系を用いた温度変化による左心室メカノエナジェティクス解析　―　TRPV1の役割　―2020
- Author(s)
  小畑孝二，森田啓之，高木　都
- Organizer
  第97回　日本生理学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K11125
[Presentation] 左心室力学的エネルギー学的性質への新規ミオシンアクチベーター, omecamtiv mecarbilの効果2016
- Author(s)
  小畑孝二、森田啓之、高木　都
- Organizer
  第93回日本生理学会
- Place of Presentation
  札幌
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-25460283
[Presentation] ラット摘出心臓の血液交叉灌流実験系を用いたメカノエナジェティクスとカルシウムイメージング解析法の開発2015
- Author(s)
  小畑孝二、森田啓之、高木　都
- Organizer
  第62回中部日本生理学会
- Place of Presentation
  富山
- Year and Date
  2015-11-13
- Data Source
  KAKENHI-PROJECT-25460283
[Presentation] 左心室力学的エネルギー学的性質へのミオシンアクチベーターとSERCAアクチベーターの効果の検討2015
- Author(s)
  小畑孝二、森田啓之、高木　都
- Organizer
  第25回日本病態生理学会
- Place of Presentation
  松山
- Year and Date
  2015-07-31
- Data Source
  KAKENHI-PROJECT-25460283
[Presentation] 液交叉灌流実験系を用いたラット摘出心臓のカプサイシン投与によるメカノエナジェティクス解析―高温との比較―2014
- Author(s)
  小畑孝二、その他
- Organizer
  第91回日本生理学会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-25460283
[Presentation] Positive and negative inotropic effects of left ventricular mechanical work and energetics in hypothermic and hyperthermic rat hearts.2013
- Author(s)
  Obata K, Takeshita D, Mitsuyama S, Abe C,Morita H, Takaki M
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-22500487
[Presentation] SERCA2a過剰発現ラットにおけるイソプロテレノール誘導肥大心の左心室メカノエナジェティクスに関する研究2013
- Author(s)
  小畑孝二、その他
- Organizer
  第23回日本病態生理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25460283
[Presentation] 血液交叉灌流実験系を用いたラット摘出心臓の高温条件下におけるメカノエナジェティクス解析2013
- Author(s)
  小畑孝二、その他
- Organizer
  第60回中部日本生理学会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-25460283
[Presentation] Interaction between osteoblast and neurons in co-culture system.2013
- Author(s)
  浅田啓嗣, 小泉宗久, 小畑孝二, 高木都,田中康仁
- Organizer
  第28回日本整形外科学会基礎学術集会.
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22500487
[Presentation] Left ventricular mechanoenergetics in isoproterenol-induced hypertrophied SERCA2a transgenic rats2012
- Author(s)
  Mitsuyama S, Obata K, Takeshita D, Ito H, Takaki M
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  長野県松本文化会館長野
- Data Source
  KAKENHI-PROJECT-22790216
[Presentation] Na^+/H^+exchanger-1 blocker treatment reversed changes in calcium transient in myocardial slices from isoproterenol-induced hypertrophied rat left ventricles2012
- Author(s)
  Takeshita D, Hattori H, Matsuoka S, Shibata M, Kimb B, Takeuchi A, Zhang GX, Obata K, Takaki M
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  長野県松本文化会館長野
- Data Source
  KAKENHI-PROJECT-22790216
[Presentation] Suppressed Ca^<2+> handling and cross-bridge cycling underlie negative inotropism in hyperthermic rat hearts2012
- Author(s)
  Obata K, Takeshita D, Mitsuyama S, Zhang G-X, Takaki M
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  長野県松本文化会館長野
- Data Source
  KAKENHI-PROJECT-22790216
[Presentation] SERCA2a過剰発現ラットにおけるイソプロテレノール持続投与による肥大心の左室力学的エネルギー学的性質2012
- Author(s)
  光山晋一、小畑孝二, その他
- Organizer
  第89回日本生理学会
- Place of Presentation
  松本(長野県松本文化会館)
- Data Source
  KAKENHI-PROJECT-22790216
[Presentation] SERCA2a過剰発現心臓の力学的エネルギー学的性質について2012
- Author(s)
  小畑孝二,竹下大輔,高木都
- Organizer
  第22回日本病態生理学会
- Place of Presentation
  大分
- Data Source
  KAKENHI-PROJECT-22500487
[Presentation] Na^+/H^+ exchanger-1阻害薬は、イソプロテレノール誘導肥大心の心筋スライスにおいてCa^<2+>トランジェントを正常化する2012
- Author(s)
  竹下大輔、小畑孝二, その他
- Organizer
  第89回日本生理学会
- Place of Presentation
  松本(長野県松本文化会館)
- Data Source
  KAKENHI-PROJECT-22790216
[Presentation] The role of satellite cells in afferent responses in sensory neurons to mechanical stimulation of osteoblasts in co-culture system2012
- Author(s)
  Asada K, Obata K, Horiguchi K, Takaki M
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  松本
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-22500487
[Presentation] 血液交叉灌流摘出ラット心臓において、高温条件下ではカルシウムハンドリングおよびクロスブリッジ機構の抑制によって収縮力が低下する2012
- Author(s)
  小畑孝二, その他
- Organizer
  第89回日本生理学会
- Place of Presentation
  松本(長野県松本文化会館)
- Data Source
  KAKENHI-PROJECT-22790216
[Presentation] 選択的セロトニン再取り込み阻害薬とセロトニン受容体作動薬が腸壁内神経損傷後のinvivo神経再建に与える効果の比較2012
- Author(s)
  川原勲,國安弘基,後藤桂,小畑孝二,藤井久男,高木都
- Organizer
  第5回J-FD研究会
- Place of Presentation
  東京
- Year and Date
  2012-11-10
- Data Source
  KAKENHI-PROJECT-22500487
[Presentation] Symposium 45 New approach of analysis for cardiac function using cross-circulation system with blood Cardiac mechanoenergetics in SERCA2a transgenic rats2011
- Author(s)
  Zhang G-X, Obata K, Takaki M
- Organizer
  第88回日本生理学会大会・第116回日本解剖学会総会・全国学術集会合同大会
- Place of Presentation
  パシフィコ横浜会議センター横浜
- Data Source
  KAKENHI-PROJECT-22790216
[Presentation] Comparison of afferent responses from osteoblasts to sensory neurons in neonatal, juvenile, and adult mice in co-culturesystem2011
- Author(s)
  Asada K, Obata K, Aoki K, Zhang GX, Matsuyoshi H, Takaki M
- Organizer
  第88回日本生理学会大会
- Place of Presentation
  横浜
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22500487
[Presentation] 血液交叉灌流摘出ラット心臓の高温条件下におけるメカノエナジェティクスの研究2011
- Author(s)
  小畑孝二, その他
- Organizer
  第21回日本病態生理学会
- Place of Presentation
  東京(日本大学医学部)
- Data Source
  KAKENHI-PROJECT-22790216
[Presentation] 血液交叉灌流摘出ラット心臓の高温条件下におけるメカノエナジェティクスの研究2011
- Author(s)
  小畑孝二, 竹下大輔, 光山晋一, 伊藤治男, 高木都
- Organizer
  第21回日本病態生理学会
- Place of Presentation
  日本大学医学部東京
- Data Source
  KAKENHI-PROJECT-22790216
[Presentation] A novel NHE-1 inhibitor ameliorates cardiac Ca^<2+> handling impairment and prevents the development of cardiac remodeling in isoproterenol-infused rats2011
- Author(s)
  Takeshita D, Zhang GX, Obata K, Misawa H, Matsuyoshi H, Takaki M
- Organizer
  第88回日本生理学会大会・第116回日本解剖学会総会・全国学術集会合同大会
- Place of Presentation
  パシフィコ横浜会議センター横浜
- Data Source
  KAKENHI-PROJECT-22790216
[Presentation] Comparison of afferent responses from osteoblasts to sensory neurons in neonatal, juvenile, and adult mice in co-culture system.2011
- Author(s)
  Asada K, Obata K, Aoki K,Zhang GX, Matsuyoshi H, Takaki M
- Organizer
  第88回日本生理学会大会
- Place of Presentation
  横浜
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22500487
[Presentation] 骨芽細胞から知覚神経への求心性経路におけるサテライト細胞の役割2010
- Author(s)
  浅田啓嗣,小畑孝二,青木久美子,張国興,松吉ひろ子,高木都
- Organizer
  第38回自律神経生理研究会
- Place of Presentation
  東京
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-22500487
[Presentation] 新しいカルパイン阻害剤SNJ-1945添加心筋保護液の虚血再灌流障害防止効果:ラット血液交叉灌流摘出心臓標本を用いて2010
- Author(s)
  吉川義朗, 張国興, 小畑孝二, 大賀好美, 松吉ひろ子, 谷口繁樹, 高木都
- Organizer
  第31回日本循環制御医学会総会
- Place of Presentation
  千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-22790216
[Presentation] イソプロテレノール誘導性肥大心におけるCa^<2+>トランジェントと経口Na+/H+交換体(NHE-1)阻害薬の肥大抑制作用2010
- Author(s)
  柴田宗孝, 張国興, 小畑孝二, 竹下大輔, 三澤裕美, 松吉ひろ子, 高木都
- Organizer
  第31回日本循環制御医学会総会
- Place of Presentation
  千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-22790216
[Presentation] 骨芽細胞から知覚神経への求心性経路におけるATPの関与を共培養実験系により解析する.2010
- Author(s)
  浅田啓嗣,小畑孝二,青木久美子,張国興,松吉ひろ子,高木都
- Organizer
  第63回自律神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-22500487
[Presentation] Afferent pathways from osteoblasts to sensory neurons activated by mechanical stimulation in co-culture system.2010
- Author(s)
  Asada K, Obata K, Aoki K, Zhang GX, Matsuyoshi H, Takaki M
- Organizer
  第87回日本生理学会大会.
- Place of Presentation
  盛岡
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-22500487
[Presentation] 骨芽細胞から知覚神経への求心性経路におけるATPの関与を共培養実験系により解析する2010
- Author(s)
  浅田啓嗣, 小畑孝二, 青木久美子, 張国興, 松吉ひろ子, 高木都
- Organizer
  第63回自律神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-22500487
[Presentation] ラット急性虚血モデルにおけるカルパイン阻害薬の作用-1心拍あたりの総機械エネルギー(PVA)解析から-2010
- Author(s)
  田中みどり, 張国興, 小畑孝二, 松吉ひろ子, 吉川義朗, 竹下大輔, 三澤裕美, 谷口繁樹, 高木都
- Organizer
  第103回近畿生理学談話会
- Place of Presentation
  大阪大学銀杏会館
- Year and Date
  2010-10-02
- Data Source
  KAKENHI-PROJECT-22790216
[Presentation] Na^+/H^+交換体阻害薬経口投与によるイソプロテレノール誘導性肥大心の肥大抑制作用とCa^<2+>トランジェントへの影響2010
- Author(s)
  竹下大輔, 柴田宗孝, 服部宇孜, 張国興, 小畑孝二, 松吉ひろ子, 三澤裕美, 高木都
- Organizer
  第103回近畿生理学談話会
- Place of Presentation
  大阪大学銀杏会館
- Year and Date
  2010-10-02
- Data Source
  KAKENHI-PROJECT-22790216
[Presentation] An experimental study in transgenic rat models.2010
- Author(s)
  Obata K
- Organizer
  BBSRC Japan Partnering Programme 2007-2011.CARDIAC ELECTRO-MECHANICAL FUNCTION Cell-Organ Cross-Talk Revealed via Integration of Experiments and Models.
- Place of Presentation
  Oxford.UK
- Data Source
  KAKENHI-PROJECT-22790216
[Presentation] Afferent pathways from osteoblasts to sensory neurons activated by mechanical stimulation in co-culture system.2010
- Author(s)
  Asada K, Obata K, Aoki K, Zhang GX, Matsuyoshi H, Takaki M
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-22500487
[Presentation] Overexpression of calmodulin in cardiomyocytes induces cardiachypertrophy by a calcineurin-dependent pathway.2009
- Author(s)
  Obata K, et al.
- Organizer
  第102回近畿生理学談話会
- Place of Presentation
  大阪
- Year and Date
  2009-12-13
- Data Source
  KAKENHI-PROJECT-20791366
[Presentation] Effects of HMG-CoA reductase inhibitor, pitavastatin on cardiac function and survival in a rat model of hypertensive heart failure. BBSRC Japan Partnering Programme 2007-20112009
- Author(s)
  Obata K
- Organizer
  The 36th International Congress of Physiological Science. Satellite Symposium #8
- Place of Presentation
  In Benesse Art Site Naoshima. Kagawa
- Data Source
  KAKENHI-PROJECT-20791366
[Presentation] 共培養実験系を用いた神経細胞と骨芽細胞の細胞間相互作用の検討2009
- Author(s)
  小畑孝二、浅田啓嗣、青木久美子、高木都
- Organizer
  第37回自律神経生理研究会
- Place of Presentation
  東京
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-20791366
[Presentation] 共培養実験系を用いた神経細胞と破骨細胞の細胞間相互作用の検討2009
- Author(s)
  小畑孝二、須賀智子、後藤滋巳、戸苅彰史
- Organizer
  第82回日本薬理学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20791366
[Presentation] 共培養実験系における骨芽細胞と神経細胞の機能的細胞間相互作用2008
- Author(s)
  小畑孝二, 古野忠秀, 中西守, 戸苅彰史
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] Direct neurite-osteoclastic cell communication in co-culture system.2008
- Author(s)
  Obata K, Suga S, Goto S, Togari A
- Organizer
  56 Annual Meeting of Japanese Association for Dental Research
- Place of Presentation
  Nagoya
- Year and Date
  2008-11-30
- Data Source
  KAKENHI-PROJECT-20592193
[Presentation] Adrenergic regulation of clock genes expression in osteoblast-like MC3T3-E1 cells2008
- Author(s)
  Koji Obata, Akifumi Togari
- Organizer
  The 81st Annual Meeting of The Japanese Pharmacological Society
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-03-18
- Data Source
  KAKENHI-PROJECT-20592193
[Presentation] 共培養実験系における骨芽細胞と神経細胞の機能的相互作用2008
- Author(s)
  小畑孝二、近藤久貴、新井通次、戸苅彰史
- Organizer
  第26回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20791366
[Presentation] 破骨細胞と神経細胞の共培養実験法の確立と細胞間相互作用の検討2008
- Author(s)
  小畑孝二、戸苅彰史
- Organizer
  第45回口腔組織培養学会
- Place of Presentation
  松本
- Year and Date
  2008-11-15
- Data Source
  KAKENHI-PROJECT-20791366
[Presentation] 骨芽細胞と神経細胞の共培養実験系におけるα-アドレナリン受容体を介した相互作用2008
- Author(s)
  小畑孝二, 戸苅彰史
- Organizer
  第50回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20791366
[Presentation] 共培養実験系における神経細胞と破骨細胞の相互作用2008
- Author(s)
  須賀智子、小畑孝二、古野忠秀、近藤久貴、新井通次、中西守、後藤滋巳、戸苅彰史
- Organizer
  第50回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20791366
[Presentation] 共培養系における神経細胞と破骨細胞の相互作用2008
- Author(s)
  須賀智子、小畑孝二、後藤滋巳、戸苅彰史
- Organizer
  第50回歯科基礎医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-23
- Data Source
  KAKENHI-PROJECT-20592193
[Presentation] 骨芽細胞におけるアドレナリン受容体刺激による時計遺伝子発現の制御2008
- Author(s)
  小畑孝二, 戸苅彰史
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] Direct Neurite-osteoclastic Cell Communication in Co-culture System2008
- Author(s)
  Koji. Obata, Satoko Suga, Shigemi Goto, Akifumi Togari
- Organizer
  第56回国際歯科研究学会日本部会学術大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20791366
[Presentation] Demonstration of direct neurite-osteoblastic cell communication in vitro co-culture system.2008
- Author(s)
  Obata, K., Furuno, T., Nakanishi, M., Togari, A.
- Organizer
  The 81th Annual Meeting of The Japanese Pharmacological Society.
- Place of Presentation
  Yokohama
- Year and Date
  2008-03-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] Adrenergic regulation of clock gene expression in osteoblast-like MC3T3-E1 cells.2008
- Author(s)
  Obata, K., Togari, A.
- Organizer
  The 81th Annual Meeting of The Japanese Pharmacological Society.
- Place of Presentation
  Yokohama
- Year and Date
  2008-03-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] 共培養実験系における骨芽細胞の機能的相互作用.2007
- Author(s)
  Obata, K., Kinpara, K., Suga, S., Furuno, T., Nakanishi, M., Goto S., Togari, A.
- Organizer
  The 111th Kinki Branch Meeting of The Japanese Pharmacological Society.
- Place of Presentation
  Nagoya
- Year and Date
  2007-06-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] 骨芽細胞と神経細胞の共培養実験法の確立と細胞間相互作用の検討.2007
- Author(s)
  Obata, K., Furuno, T., Nakanishi, M., Togari, A.
- Organizer
  The 44th Annual Meeting of Japan Tissue Culture Society for Dental Reseach.
- Place of Presentation
  Matsuyama
- Year and Date
  2007-12-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] 小畑孝二,古野忠秀,中西守,戸苅彰史2007
- Author(s)
  小畑孝二, 古野忠秀, 中西守, 戸苅彰史
- Organizer
  第44回日本口腔組織培養学会
- Place of Presentation
  松山
- Year and Date
  2007-12-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] 共培養実験系における骨芽細胞と神経細胞の機能的相互作用2007
- Author(s)
  小畑孝二, 金原享子, 須賀智子, 古野忠秀, 中西守, 後藤滋巳, 戸苅彰史
- Organizer
  第111回日本薬理学会近畿部会
- Place of Presentation
  名古屋
- Year and Date
  2007-06-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] ラット摘出心臓の血液交叉灌流実験系を用いた高温条件による陰性変力作用のメカニズムについて
- Author(s)
  小畑孝二、安部　力、森田　啓之、高木　都
- Organizer
  第24回日本病態生理学会
- Place of Presentation
  北九州国際会議場
- Year and Date
  2014-08-09 – 2014-08-10
- Data Source
  KAKENHI-PROJECT-25460283
[Presentation] Positive and negative inotropic effects of left ventricular mechanical work and energetics in hypothermic and hyperthermic rat hearts.
- Author(s)
  Obata Koji
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22500487
[Presentation] ラット摘出心臓における高温条件下での陰性変力作用について　― TRPV1の関与 ―
- Author(s)
  小畑孝二、森田　啓之、高木　都
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25460283
[Presentation] 病的心臓のメカノエナジェティクスにおけるSERCA2a過剰発現の影響
- Author(s)
  小畑孝二、光山　晋一、竹下　大輔、森田　啓之、高木　都
- Organizer
  第35回日本循環制御医学会
- Place of Presentation
  九州大学医学部　百年講堂
- Year and Date
  2014-07-04 – 2014-07-05
- Data Source
  KAKENHI-PROJECT-25460283

1. YOKOTA Mitsuhiro (50201851)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
2. TAKAKI Miyako (00033358)

# of Collaborated Projects: 4 results

# of Collaborated Products: 43 results
3. ARAI Michitugu (20097538)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. IZAWA Hideo (80402569)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TOGARI Akifumi (80126325)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
6. KONDO Hisataka (40469002)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ZHANG Guo-Xing (90444728)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ASADA Keiji (10440851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
9. Nakai Junichi (80237198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Ohkura Masamichi (70369172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAGATA Kohzo (20378227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HIRUKAWA Koji (60340147)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 松吉ひろ子 (10448772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. 茂木眞希雄 (00174334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 森田あや美 (70301629)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MORITA Hironobu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 張國興

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
18. 篠原正浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 国安弘基

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

obata koji 小畑 孝二

Obata Koji 小畑 孝二

OBATA Koji 小畑 孝二

Research Projects

Research Products

Co-Researchers

Development of therapeutic agents for heart failure by altering energy metabolism using cardiac mechanoenergetics analysisPrincipal Investigator

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Development of heart failure therapy by altering cardiac energy metabolismPrincipal Investigator

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Development of whole heart calcium imaging system with two different waves using modified G-CaMP-DsRed-coexpressed transgenic rat model in the blood-perfused excised heart preparationPrincipal Investigator

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The role of the sympathetic nervous system in physiologicalresponse to mechanical stress

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Establishment of simultaneous real-time measurement system for myocardial mechanenergetics and calcium dynamics in rat whole hearts.Principal Investigator

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Pharmacological study on circadian gene expression induced by sympathetic nervous activity in osteoblastic cells.

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Role of regulators of calcineurin 1, RCAN1 as an endogenous calcineur in inhibitor, on osteoolast differentiationPrincipal Investigator

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全ゲノム罹患同胞対連鎖解析及び候補遺伝子関連解析による心筋梗塞感受性遺伝子の同定

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内因性カルシニューリン抑制蛋白質ZAKI-4βの心筋肥大化制御分子としての役割Principal Investigator

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罹患同胞対連鎖解析及び候補遺伝子間連解析による心筋梗塞感受性遺伝子の同定

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Population based study of genetic risk and gene-environment interaction in lifestyle-related diseases including coronary artery diseases(KING Study)

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Pharmacological study on bone metabolism by nervous activity

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[Journal Article] 心臓病治療薬開発に向けた左心室メカノエナジェティクス解析の重要性2022

Author(s)

obata koji 小畑孝二

Obata Koji 小畑孝二

OBATA Koji 小畑孝二