Watashi Koichi 渡士幸一

… Alternative Names

WATASHI Koichi 渡士幸一

渡士幸一ワタシコウイチ

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Researcher Number	40378948
Other IDs
External Links
Affiliation (Current)	2025: 国立感染症研究所, 治療薬・ワクチン開発研究センター, 総括研究官
Affiliation (based on the past Project Information) *help	2021 – 2024: 国立感染症研究所, 治療薬・ワクチン開発研究センター, 総括研究官 2023: 国立感染症研究所, 治療薬・ワクチン開発研究センター, 治療薬開発総括研究官 2020: 国立感染症研究所, ウイルス第二部, 主任研究官 2019 – 2020: 国立感染症研究所, 治療薬・ワクチン開発研究センター, 治療薬開発総括研究官 2011 – 2018: 国立感染症研究所, ウイルス第二部, 主任研究官 2005 – 2006: 京都大学, ウイルス研究所, 助手
Review Section/Research Field	Principal Investigator Virology / Basic Section 49060:Virology-related / Science and Engineering Except Principal Investigator Basic Section 49060:Virology-related / Basic Section 43040:Biophysics-related / Complex Systems Disease Theory
Keywords	Principal Investigator ウイルス / HBV / HCV / 複製 / 肝炎 / B型肝炎ウイルス / 肝炎ウイルス / 侵入 / 天然物 / 抗ウイルス … More / ウィルス / EGFR / NTCP / 感染 / 微小管 / 化合物 / 翻訳後修飾 / 転写 / LXR / 生理活性 / 抗ウイルス剤 / phospholipase / PLD / 感染症 / 薬学 / C型肝炎 / インターフェロン / シクロフィリン / シクロスポリン … More Except Principal Investigator 抗ウイルス薬 / 宿主ーウイルス相互作用 / クライオ電子顕微鏡単粒子解析 / 感染受容体 / B型肝炎ウイルス / 宿主因子 / クライオ電子顕微鏡 / エンベロープタンパク質 / ウイルス受容体 / 構造生物学研究 / Xタンパク質 / 構造生物学 / Nタンパク質 / 新型コロナウイルス / ウイルス学 / ウイルス感染症 / ウイルス / HIV / ヒト免疫不全ウイルス / C型肝炎ウイルス / エボラウイルス / 数理解析 Less

Regulation of hepatitis B virus entry by the receptor complex and its significance in determination of host tropismPrincipal Investigator
- Principal Investigator
  
  渡士幸一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  National Institute of Infectious Diseases
Structural biology of the hepatitis B virus entry and its inhibition
- Principal Investigator
  
  野村紀通
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Kyoto University
Structure and functional analysis of the SARS-CoV-2 Nucleocapsid Protein
- Principal Investigator
  
  Park Sam-Yong
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Yokohama City University
Molecular mechanism, dynamics, and interaction with environment in the hepatitis B virus entry systemPrincipal Investigator
- Principal Investigator
  
  Watashi Koichi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  National Institute of Infectious Diseases
Mechanistic analysis of hepatitis B virus entry and the host factors using new cell culture systemsPrincipal Investigator
- Principal Investigator
  
  Watashi Koichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
Systems Virology for understanding viral pathogenesis
- Principal Investigator
  
  Noda Takeshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Complex Systems Disease Theory
- Research Institution
  Kyoto University
ウイルス感染増殖系を基盤とした天然化合物新規生理機能の同定Principal Investigator
- Principal Investigator
  
  渡士幸一
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  National Institute of Infectious Diseases
Analysis of regulation mechanisms of hepatitis B virus life cycle by kinases and post-translational modificationsPrincipal Investigator
- Principal Investigator
  
  Watashi Koichi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
肝炎ウイルス感染増殖系を用いた天然物生理活性解析Principal Investigator
- Principal Investigator
  
  渡士幸一
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  National Institute of Infectious Diseases
Mechanistic analysis of hepatitis C virus life cycle using small moleculesPrincipal Investigator
- Principal Investigator
  
  WATASHI Koichi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
シクロスポリンを用いたC型肝炎ウイルスゲノム複製機構の解析Principal Investigator
- Principal Investigator
  
  渡士幸一
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  Kyoto University

[Book] Encyclopedia of Signaling Molecules, 2nd Edition2017
- Author(s)
  Tsukuda S, Iwamoto M, Watashi K
- Publisher
  Springer Nature
- Data Source
  KAKENHI-PROJECT-26460565
[Book] Encyclopedia of Signaling Molecules, 2nd Edition2017
- Author(s)
  Tsukuda S, Iwamoto M, Watashi K
- Publisher
  Springer Nature
- Data Source
  KAKENHI-PROJECT-17H04085
[Book] エッセンシャルウイルス学2014
- Author(s)
  渡士幸一
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-23790514
[Book] エッセンシャルウイルス学2014
- Author(s)
  渡士幸一
- Publisher
  南江堂
- Data Source
  KAKENHI-PUBLICLY-24102537
[Book] 肝疾患Review2014-20152014
- Author(s)
  渡士幸一
- Publisher
  日本メディカルセンター
- Data Source
  KAKENHI-PUBLICLY-24102537
[Book] 肝疾患Review2014-20152014
- Author(s)
  渡士幸一
- Publisher
  日本メディカルセンター
- Data Source
  KAKENHI-PROJECT-23790514
[Book] エッセンシャルウイルス学
- Author(s)
  渡士幸一
- Publisher
  南江堂(印刷中)
- Data Source
  KAKENHI-PROJECT-23790514
[Book] 肝疾患Review2014-2015
- Author(s)
  渡士幸一
- Publisher
  日本メディカルセンター(印刷中)
- Data Source
  KAKENHI-PROJECT-23790514
[Journal Article] Multiscale modeling of HBV infection integrating intra- and intercellular viral propagation to analyze extracellular viral markers2024
- Author(s)
  Kitagawa Kosaku、Kim Kwang Su、Iwamoto Masashi、Hayashi Sanae、Park Hyeongki、Nishiyama Takara、Nakamura Naotoshi、Fujita Yasuhisa、Nakaoka Shinji、Aihara Kazuyuki、Perelson Alan S.、Allweiss Lena、Dandri Maura、Watashi Koichi、Tanaka Yasuhito、Iwami Shingo
- Journal Title
  
  PLOS Computational Biology
  
  Volume: 20 Issue: 3 Pages: 1011238-1011238
- DOI
  10.1371/journal.pcbi.1011238
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07442, KAKENHI-PROJECT-21K19813, KAKENHI-PROJECT-23K27415
[Journal Article] Synthesis of the full-length hepatitis B virus core protein and its capsid formation2024
- Author(s)
  Aoki Keisuke、Tsuda Shugo、Ogata Naoko、Kataoka Michiyo、Sasaki Jumpei、Inuki Shinsuke、Ohno Hiroaki、Watashi Koichi、Yoshiya Taku、Oishi Shinya
- Journal Title
  
  Organic &; Biomolecular Chemistry
  
  Volume: 22 Issue: 11 Pages: 2218-2225
- DOI
  10.1039/d3ob02099a
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19366, KAKENHI-PROJECT-22KJ1661, KAKENHI-PROJECT-23K27415
[Journal Article] Harnessing a T1 Phage-Derived Spanin for Developing Phage-Based Antimicrobial Development2024
- Author(s)
  Yamashita Wakana、Ojima Shinjiro、Tamura Azumi、Azam Aa Haeruman、Kondo Kohei、Yuancheng Zhang、Cui Longzhu、Shintani Masaki、Suzuki Masato、Takahashi Yoshimasa、Watashi Koichi、Tsuneda Satoshi、Kiga Kotaro
- Journal Title
  
  BioDesign Research
  
  Volume: 6 Pages: 0028-0028
- DOI
  10.34133/bdr.0028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KJ1099, KAKENHI-PROJECT-23K06556, KAKENHI-PROJECT-22K20575, KAKENHI-PROJECT-23K27415
[Journal Article] Structural basis of hepatitis B virus receptor binding2024
- Author(s)
  Asami Jinta、Park Jae-Hyun、Nomura Yayoi、Kobayashi Chisa、Mifune Junki、Ishimoto Naito、Uemura Tomoko、Liu Kehong、Sato Yumi、Zhang Zhikuan、Muramatsu Masamichi、Wakita Takaji、Drew David、Iwata So、Shimizu Toshiyuki、Watashi Koichi、Park Sam-Yong、Nomura Norimichi、Ohto Umeharu
- Journal Title
  
  Nature Structural & Molecular Biology
  
  Volume: 31 Issue: 3 Pages: 447-454
- DOI
  10.1038/s41594-023-01191-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19447, KAKENHI-PROJECT-23K18211, KAKENHI-PROJECT-23K18239, KAKENHI-PROJECT-22K15046, KAKENHI-PLANNED-19H05777, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-23K23820, KAKENHI-PROJECT-23K24142, KAKENHI-PROJECT-23K27415
[Journal Article] An ACAT inhibitor regulates SARS-CoV-2 replication and antiviral T cell activity2023
- Author(s)
  Nathalie M Schmidt, Rory Peters, Rachel Brown, Hao Wang, Leo Swadling, COVIDsortium Investigators, Joseph Newman, Nazia Thakur, Kaho Shionoya, Sophie B Morgan, Timothy SC Hinks, Koichi Watashi, Dalan Bailey, Scott B Hansen, Mala K Maini, Jane A McKeating
- Journal Title
  
  PLoS Pathog
  
  Volume: 3 Issue: 5 Pages: e1011323-e1011323
- DOI
  10.1371/journal.ppat.1011323
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KJ2816, KAKENHI-PROJECT-23K27415
[Journal Article] A versatile method to profile hepatitis B virus DNA integration2023
- Author(s)
  Fukano Kento、Wakae Kousho、Nao Naganori、Saito Masumichi、Tsubota Akihito、Toyoshima Takae、Aizaki Hideki、Iijima Hiroko、Matsudaira Takahiro、Kimura Moto、Watashi Koichi、Sugiura Wataru、Muramatsu Masamichi
- Journal Title
  
  Hepatology Communications
  
  Volume: 7 Issue: 12
- DOI
  10.1097/hc9.0000000000000328
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19447, KAKENHI-PROJECT-22K15481, KAKENHI-PROJECT-22K08587, KAKENHI-PROJECT-23K24142, KAKENHI-PROJECT-23K27415
[Journal Article] Selective inhibition of hepatitis B virus internalization by oxysterol derivatives2023
- Author(s)
  Oshima Mizuki、Stappenbeck Frank、Ohashi Hirofumi、Iwamoto Masashi、Fukano Kento、Kusunoki Atsuto、Zheng Xin、Wang Feng、Morishita Ryo、Aizaki Hideki、Suzuki Ryosuke、Muramatsu Masamichi、Kuramochi Kouji、Sureau Camille、Parhami Farhad、Watashi Koichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 675 Pages: 139-145
- DOI
  10.1016/j.bbrc.2023.07.014
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19447, KAKENHI-PROJECT-22K15481, KAKENHI-PROJECT-23K24142, KAKENHI-PROJECT-23K27415
[Journal Article] Oxidative stress sensor Keap1 recognizes HBx protein to activate the Nrf2/ARE signaling pathway, thereby inhibiting hepatitis B virus replication2023
- Author(s)
  Ariffianto Adi、Deng Lin、Abe Takayuki、Matsui Chieko、Ito Masahiko、Ryo Akihide、Aly Hussein Hassan、Watashi Koichi、Suzuki Tetsuro、Mizokami Masashi、Matsuura Yoshiharu、Shoji Ikuo
- Journal Title
  
  Journal of Virology
  
  Volume: 97 Issue: 10 Pages: 1-35
- DOI
  10.1128/jvi.01287-23
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15470, KAKENHI-PROJECT-21K07040, KAKENHI-PROJECT-21K07051, KAKENHI-PROJECT-23K27415
[Journal Article] Structural insights into the HBV receptor and bile acid transporter NTCP2022
- Author(s)
  Park JH, Iwamoto M, Yun JH, Uchikubo-Kamo T, Son D, Jin Z, Yoshida H, Ohki M, Ishimoto N, Mizutani K, Oshima M, Muramatsu M, Wakita T, Shirouzu M, Liu K, Uemura T, Nomura N, Iwata S, Watashi K, Tame JRH, Nishizawa T, Lee W, Park SY.
- Journal Title
  
  Nature
  
  Volume: 606 Issue: 7916 Pages: 1027-1031
- DOI
  10.1038/s41586-022-04857-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15453, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-20H03216, KAKENHI-PROJECT-21H02449, KAKENHI-PROJECT-20K16264, KAKENHI-PLANNED-19H05779, KAKENHI-PLANNED-19H05777
[Journal Article] Engineering Cellular Biosensors with Customizable Antiviral Responses Targeting Hepatitis B Virus2020
- Author(s)
  Matsunaga Satoko、Jeremiah Sundararaj S.、Miyakawa Kei、Kurotaki Daisuke、Shizukuishi Sayaka、Watashi Koichi、Nishitsuji Hironori、Kimura Hirokazu、Tamura Tomohiko、Yamamoto Naoki、Shimotohno Kunitada、Wakita Takaji、Ryo Akihide
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 3 Pages: 100867-100867
- DOI
  10.1016/j.isci.2020.100867
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07161, KAKENHI-PROJECT-17H04085
[Journal Article] Prolyl Isomerase Pin1 Regulates the Stability of Hepatitis B Virus Core Protein.2020
- Author(s)
  Nishi M, Miyakawa K, Matsunaga S, Khatun H, Yamaoka Y, Watashi K, Sugiyama M, Kimura H, Wakita T, Ryo A.
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 8 Pages: 26-26
- DOI
  10.3389/fcell.2020.00026
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09000, KAKENHI-PROJECT-17H04085
[Journal Article] Anti‐viral effects of interferon‐λ3 on hepatitis B virus infection in cell culture2020
- Author(s)
  Yamada Norie、Murayama Asako、Shiina Masaaki、Aly Hussein Hassan、Iwamoto Masashi、Tsukuda Senko、Watashi Koichi、Tanaka Tomohisa、Moriishi Kohji、Nishitsuji Hironori、Sugiyama Masaya、Mizokami Masashi、Shimotohno Kunitada、Muramatsu Masamichi、Murata Kazumoto、Kato Takanobu
- Journal Title
  
  Hepatology Research
  
  Volume: 50 Issue: 3 Pages: 283-291
- DOI
  10.1111/hepr.13449
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07161, KAKENHI-PROJECT-19K16672, KAKENHI-PROJECT-18F18098, KAKENHI-PROJECT-17K09448, KAKENHI-PROJECT-19K07586, KAKENHI-PROJECT-17H04085
[Journal Article] N‐terminal PreS1 Sequence Regulates Efficient Infection of Cell Culture‐generated Hepatitis B Virus2020
- Author(s)
  Murayama A、Yamada N、Osaki 、Shiina 、Aly H H、Iwamoto M、Tsukuda S、Watashi K、Matsuda M、Suzuki R、Tanaka T、Moriishi K、Suzuki T、Nishitsuji H、Sugiyama M、Mizokami M、Shimotohno K、Wakita T、Muramatsu M、Liang T J、Kato T
- Journal Title
  
  Hepatology
  
  Volume: 「－」 Issue: 2 Pages: 520-532
- DOI
  10.1002/hep.31308
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18F18098, KAKENHI-PROJECT-19K07583, KAKENHI-PROJECT-19K07586, KAKENHI-PROJECT-20K08380, KAKENHI-PROJECT-17H04085, KAKENHI-PROJECT-18H02661, KAKENHI-PROJECT-18K07161
[Journal Article] Surfeit 4 contributes to the replication of hepatitis C virus using double membrane vesicles.2020
- Author(s)
  Kong L, Aoyagi H, Yang Z, Ouyang T, Matsuda M, Fujimoto A, Watashi K, Suzuki R, Arita M, Yamagoe S, Dohmae N, Suzuki T, Suzuki T, Muramatsu M, Wakita T, Aizaki H.
- Journal Title
  
  Journal of Virology
  
  Volume: 94 Issue: 2
- DOI
  10.1128/jvi.00858-19
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02661, KAKENHI-PROJECT-17K09447, KAKENHI-PROJECT-17H04085
[Journal Article] The machinery for endocytosis of epidermal growth factor receptor coordinates the transport of incoming hepatitis B virus to the endosomal network.2020
- Author(s)
  Iwamoto M, Saso W, Nishioka K, Ohashi H, Sugiyama R, Ryo A, Ohki M, Yun JH, Park SY, Ohshima T, Suzuki R, Aizaki H, Muramatsu M, Matano T, Iwami S, Sureau C, Wakita T, Watashi K
- Journal Title
  
  J Biol Chem
  
  Volume: 295 Issue: 3 Pages: 800-807
- DOI
  10.1074/jbc.ac119.010366
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16672, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-18H05103, KAKENHI-PUBLICLY-19H04839, KAKENHI-PROJECT-16H04845, KAKENHI-PROJECT-18H01139, KAKENHI-PROJECT-18J14277, KAKENHI-PROJECT-19J21455, KAKENHI-PROJECT-17H04085
[Journal Article] The Beginning of Ending Hepatitis C Virus: A Summary of the 26th International Symposium on Hepatitis C Virus and Related Viruses2020
- Author(s)
  Shin Eui-Cheol、Han Ji Won、Kang Wonseok、Kato Takanobu、Kim Seong-Jun、Zhong Jin、Kim Seungtaek、Park Su-Hyung、Sung Pil Soo、Watashi Koichi、Park Jun Yong、Windisch Marc P.、Oh Jong-Won、Wakita Takaji、Han Kwang-Hyub、Jang Sung Key
- Journal Title
  
  Viruses
  
  Volume: 12 Issue: 3 Pages: 302-302
- DOI
  10.3390/v12030302
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09447, KAKENHI-PROJECT-17H04085
[Journal Article] Troglitazone Impedes the Oligomerization of Sodium Taurocholate Cotransporting Polypeptide and Entry of Hepatitis B Virus Into Hepatocytes2019
- Author(s)
  Fukano Kento、Tsukuda Senko、Oshima Mizuki、Suzuki Ryosuke、Aizaki Hideki、Ohki Mio、Park Sam-Yong、Muramatsu Masamichi、Wakita Takaji、Sureau Camille、Ogasawara Yuki、Watashi Koichi
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 9 Pages: 3257-3257
- DOI
  10.3389/fmicb.2018.03257
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-16K08383, KAKENHI-PROJECT-16K19145, KAKENHI-PROJECT-17H04085
[Journal Article] Concept of Viral Inhibitors via NTCP.2019
- Author(s)
  1)Tsukuda S, Fukano K, Watashi K, Wakita T.
- Journal Title
  
  Semin Liver Dis.
  
  Volume: 39 Issue: 01 Pages: 78-95
- DOI
  10.1055/s-0038-1676804
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19145, KAKENHI-PROJECT-17H04085
[Journal Article] Pyrimidotriazine derivatives as selective inhibitors of HBV capsid assembly2019
- Author(s)
  Toyama M, Sakakibara N, Takeda M, Okamoto M, Watashi K, Wakita T, Sugiyama M, Mizokami M, Ikeda M, Baba M
- Journal Title
  
  Virus Res
  
  Volume: 271 Pages: 197677-197677
- DOI
  10.1016/j.virusres.2019.197677
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04085
[Journal Article] Mathematical analysis of a transformed ODE from a PDE multiscale model of hepatitis C virus infection2019
- Author(s)
  Kitagawa K., Kuniya T., Nakaoka S., Asai Y., Watashi K. and Iwami S.
- Journal Title
  
  Bulletin of Mathematical Biology
  
  Volume: 81(5) Issue: 5 Pages: 1427-1441
- DOI
  10.1007/s11538-018-00564-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0119, KAKENHI-PROJECT-18K17371, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-17H05819, KAKENHI-PROJECT-16H04845, KAKENHI-PROJECT-18H01139, KAKENHI-PROJECT-15KT0107, KAKENHI-PROJECT-16K05265, KAKENHI-PROJECT-16K13777, KAKENHI-PROJECT-17H04085
[Journal Article] Non-nucleoside hepatitis B virus polymerase inhibitors identified by an in vitro polymerase elongation assay2019
- Author(s)
  Nakajima Shogo、Watashi Koichi、Fukano Kento、Tsukuda Senko、Wakae Kousho、Aizaki Hideki、Muramatsu Masamichi、Wakita Takaji、Toyoda Tetsuya
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 55 Issue: 4 Pages: 441-452
- DOI
  10.1007/s00535-019-01643-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K23855, KAKENHI-PROJECT-19K07583, KAKENHI-PROJECT-17H04085
[Journal Article] Immunomodulatory mechanism of acyclic nucleoside phosphates in treatment of hepatitis B virus infection.2019
- Author(s)
  Murata K, Tsukuda S, Suizu F, Kimura A, Sugiyama M, Watashi K, Noguchi M, Mizokami M.
- Journal Title
  
  Hepatology
  
  Volume: 71 Issue: 5 Pages: 1533-1545
- DOI
  10.1002/hep.30956
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08896, KAKENHI-PROJECT-17K09448, KAKENHI-PROJECT-17H04085
[Journal Article] Development of an in vitro cholestatic drug-induced liver injury evaluation system using HepG2-hNTCP-C4 cells in sandwich configuration2019
- Author(s)
  Sakai Yoko、Okumura Hiroki、Iwao Takahiro、Watashi Koichi、Ito Kousei、Matsunaga Tamihide
- Journal Title
  
  Toxicology in Vitro
  
  Volume: 61 Pages: 104619-104619
- DOI
  10.1016/j.tiv.2019.104619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H01811, KAKENHI-PROJECT-17H04085
[Journal Article] Screening for inhibitor of episomal DNA identified dicumarol as a hepatitis B virus inhibitor2019
- Author(s)
  Takeuchi F, Ikeda S, Tsukamoto Y, Iwasawa Y, Qihao C, Otakaki Y, Ryota O, Yao WL, Narita R, Makoto H, Watashi K, Wakita T, Takeuchi K, Chayama K, Kogure A, Kato H, Fujita T
- Journal Title
  
  PLoS One
  
  Volume: 14 Issue: 2 Pages: e0212233-e0212233
- DOI
  10.1371/journal.pone.0212233
- NAID
  120006822498
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04085
[Journal Article] Activation of protein kinase R by hepatitis C virus RNA-dependent RNA polymerase.2019
- Author(s)
  Suzuki R, Matsuda M, Shimoike T, Watashi K, Aizaki H, Kato T, Suzuki T, Muramatsu M, Wakita T.
- Journal Title
  
  Virology
  
  Volume: 529 Pages: 226-233
- DOI
  10.1016/j.virol.2019.01.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02661, KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-17H04085
[Journal Article] Small Interfering RNA Screening for the Small GTPase Rab Proteins Identifies Rab5B as a Major Regulator of Hepatitis B Virus Production2019
- Author(s)
  Inoue Jun、Ninomiya Masashi、Umetsu Teruyuki、Nakamura Takuya、Kogure Takayuki、Kakazu Eiji、Iwata Tomoaki、Takai Satoshi、Sano Akitoshi、Fukuda Mitsunori、Watashi Koichi、Isogawa Masanori、Tanaka Yasuhito、Shimosegawa Tooru、McNiven Mark A.、Masamune Atsushi
- Journal Title
  
  Journal of Virology
  
  Volume: 93 Issue: 15
- DOI
  10.1128/jvi.00621-19
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08385, KAKENHI-PROJECT-17K09436, KAKENHI-PROJECT-17H04085
[Journal Article] From the Establishment of Hepatitis B Virus Cell Culture Systems to Drug Discovery2019
- Author(s)
  深野顕人、渡士幸一
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 139 Issue: 1 Pages: 81-87
- DOI
  10.1248/yakushi.18-00164-4
- NAID
  130007541645
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2019-01-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04085
[Journal Article] Synthesis of nucleotide analogues, EFdA, EdA and EdAP, and the effect of EdAP on hepatitis B virus replication2019
- Author(s)
  Kamata Mai、Takeuchi Toshifumi、Hayashi Ei、Nishioka Kazane、Oshima Mizuki、Iwamoto Masashi、Nishiuchi Kota、Kamo Shogo、Tomoshige Shusuke、Watashi Koichi、Kamisuki Shinji、Ohrui Hiroshi、Sugawara Fumio、Kuramochi Kouji
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 84 Issue: 2 Pages: 217-227
- DOI
  10.1080/09168451.2019.1673696
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05343, KAKENHI-PROJECT-19K16326, KAKENHI-PROJECT-19K16672, KAKENHI-PROJECT-19K05726, KAKENHI-PROJECT-17H04085
[Journal Article] Acidic polysaccharides isolated from marine algae inhibit the early step of viral infection2019
- Author(s)
  Ueno Mikinori、Nogawa Masato、Siddiqui Rokeya、Watashi Koichi、Wakita Takaji、Kato Nobuyuki、Ikeda Masanori、Okimura Takasi、Isaka Shogo、Oda Tatsuya、Ariumi Yasuo
- Journal Title
  
  International Journal of Biological Macromolecules
  
  Volume: 124 Pages: 282-290
- DOI
  10.1016/j.ijbiomac.2018.11.152
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05823, KAKENHI-PROJECT-18J00112, KAKENHI-PROJECT-18K08438, KAKENHI-PROJECT-17H04085
[Journal Article] Epidermal growth factor receptor is a host entry cofactor triggering hepatitis B virus internalization2019
- Author(s)
  M. Iwamoto, W. Saso, R. Sugiyama, K. Ishii, M. Ohki, S. Nagamori, R. Suzuki, H. Aizaki, A. Ryo, J-H Yun, S-Y Park, N. Ohtani, M. Muramatsu, S. Iwami, Y. Tanaka, C. Sureau, T. Wakita and K. Watashi
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 116 Issue: 17 Pages: 8487-8492
- DOI
  10.1073/pnas.1811064116
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-17H05819, KAKENHI-PROJECT-16H04845, KAKENHI-PROJECT-18H01139, KAKENHI-PROJECT-16KT0111, KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-15KT0107, KAKENHI-PROJECT-16K08825, KAKENHI-PROJECT-16K13777, KAKENHI-PROJECT-19K16672, KAKENHI-PROJECT-18H02413, KAKENHI-PROJECT-19J21455, KAKENHI-PROJECT-17H04085, KAKENHI-PROJECT-16H04699
[Journal Article] Retrotransposon elements among initial sites of hepatitis B virus integration into human genome in the HepG2-NTCP cell infection model2019
- Author(s)
  Chauhan R, Shimizu Y, Watashi K, Wakita T, Fukasawa M, Michalak TI
- Journal Title
  
  Cancer Genet
  
  Volume: 235-236 Pages: 39-56
- DOI
  10.1016/j.cancergen.2019.04.060
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Journal Article] Peroxiredoxin 1, a novel HBx-interacting protein, interacts with exsome component 5 and negatively regulates hepatitis B virus (HBV) propagation through degradation of HBV RNA.2019
- Author(s)
  Lin Deng, Xiang Gan, Masahiko Ito, Ming Chen, Hussein H. Aly, Chieko Matsui, Takayuki Abe, Koichi Watashi,Takaji Wakita, Tetsuro Suzuki, Toru Okamoto, Yoshiharu Matsuura, Masashi Mizokami, Ikuo Shoji, and Hak Hotta.
- Journal Title
  
  J. Virol
  
  Volume: 93 Issue: 6
- DOI
  10.1128/jvi.02203-18
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08857, KAKENHI-PROJECT-18K08004, KAKENHI-PROJECT-18F18098, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PROJECT-17H04085, KAKENHI-PROJECT-18K08001
[Journal Article] An interferon-like small chemical compound CDM-3008 suppresses hepatitis B virus through induction of interferon-stimulated genes2019
- Author(s)
  Furutani Yutaka、Toguchi Mariko、Shiozaki-Sato Yumi、Qin Xian-Yang、Ebisui Etsuko、Higuchi Shoko、Sudoh Masayuki、Suzuki Harukazu、Takahashi Nobuaki、Watashi Koichi、Wakita Takaji、Kakeya Hideaki、Kojima Soichi
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 6 Pages: e0216139-e0216139
- DOI
  10.1371/journal.pone.0216139
- NAID
  120006644069
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15833, KAKENHI-PROJECT-17H04085
[Journal Article] Bardoxolone methyl as a novel potent antiviral agent against hepatitis B and C viruses in human hepatocyte cell culture systems.2019
- Author(s)
  Nio Yasunori、Sasai Machiko、Akahori Yuichi、Okamura Hitomi、Hasegawa Hikari、Oshima Mizuki、Watashi Koichi、Wakita Takaji、Ryo Akihide、Tanaka Yasuhito、Hijikata Makoto
- Journal Title
  
  Antiviral Research
  
  Volume: 169 Pages: 104537-104537
- DOI
  10.1016/j.antiviral.2019.104537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09447, KAKENHI-PROJECT-17H04085
[Journal Article] Screening of microRNAs for a repressor of hepatitis B virus replication2018
- Author(s)
  Naito Y, Hamada-Tsutsumi S, Yamamoto Y, Kogure A, Yoshioka Y, Watashi K, Ochiya T, Tanaka Y
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 52 Pages: 29857-29868
- DOI
  10.18632/oncotarget.25557
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04085
[Journal Article] A Single Adaptive Mutation in Sodium Taurocholate Cotransporting Polypeptide Induced by Hepadnaviruses Determines Virus Species Specificity2018
- Author(s)
  Takeuchi Junko S.、Fukano Kento、Iwamoto Masashi、Tsukuda Senko、Suzuki Ryosuke、Aizaki Hideki、Muramatsu Masamichi、Wakita Takaji、Sureau Camille、Watashi Koichi
- Journal Title
  
  Journal of Virology
  
  Volume: 93 Issue: 5 Pages: 04132-18
- DOI
  10.1128/jvi.01432-18
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-16K19145, KAKENHI-PROJECT-16J40232, KAKENHI-PROJECT-17H04085, KAKENHI-PROJECT-17K15708
[Journal Article] Cell and Animal Models for Studying Hepatitis B Virus Infection and Drug Development2018
- Author(s)
  Hu J, Lin YY, Chen PJ, Watashi K, Wakita T
- Journal Title
  
  Gastroenterology
  
  Volume: 156 Issue: 2 Pages: 338-354
- DOI
  10.1053/j.gastro.2018.06.093
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Journal Article] Inhibitory effect of fasiglifam on hepatitis B virus infections through suppression of the sodium taurocholate cotransporting polypeptide2018
- Author(s)
  Nio Y, Akahori Y, Okamura H, Watashi K, Wakita T, Hijikata M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 501 Issue: 3 Pages: 820-825
- DOI
  10.1016/j.bbrc.2018.04.199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04085
[Journal Article] The aryl hydrocarbon receptor?cytochrome P450 1A1 pathway controls lipid accumulation and enhances the permissiveness for hepatitis C virus assembly2018
- Author(s)
  Ohashi Hirofumi、Nishioka Kazane、Nakajima Syo、Kim Sulyi、Suzuki Ryosuke、Aizaki Hideki、Fukasawa Masayoshi、Kamisuki Shinji、Sugawara Fumio、Ohtani Naoko、Muramatsu Masamichi、Wakita Takaji、Watashi Koichi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 293 Issue: 51 Pages: 19559-19571
- DOI
  10.1074/jbc.ra118.005033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09447, KAKENHI-PROJECT-18K05343, KAKENHI-PROJECT-18J14277, KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-17H04085, KAKENHI-PROJECT-16H04699
[Journal Article] A PDE multiscale model of hepatitis C virus infection can be transformed to a system of ODEs2018
- Author(s)
  K. Kitagawa, S. Nakaoka, Y. Asai, K. Watashi, S. Iwami
- Journal Title
  
  Journal of Theoretical Biology
  
  Volume: 48 Pages: 80-85
- DOI
  10.1016/j.jtbi.2018.04.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15KT0107, KAKENHI-PROJECT-26287025, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-17H05819, KAKENHI-PROJECT-16H04845, KAKENHI-PROJECT-18H01139, KAKENHI-PROJECT-16K05265, KAKENHI-PROJECT-16K13777, KAKENHI-PROJECT-17H04085
[Journal Article] Flap endonuclease 1 is involved in cccDNA formation in the hepatitis B virus2018
- Author(s)
  Kitamura Kouichi、Que Lusheng、Shimadu Miyuki、Koura Miki、Ishihara Yuuki、Wakae Kousho、Nakamura Takashi、Watashi Koichi、Wakita Takaji、Muramatsu Masamichi
- Journal Title
  
  PLOS Pathogens
  
  Volume: 14 Issue: 6 Pages: e1007124-e1007124
- DOI
  10.1371/journal.ppat.1007124
- NAID
  120006602144
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09412, KAKENHI-PROJECT-17K16839, KAKENHI-PROJECT-17H04085
[Journal Article] Novel stable HBV producing cell line systems for expression and screening antiviral inhibitor of hepatitis B virus in human hepatoma cell line2018
- Author(s)
  Ogura N, Ogawa K, Watashi K, Ito T, Wakita T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 498 Issue: 1 Pages: 64-71
- DOI
  10.1016/j.bbrc.2018.02.175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-17H04085
[Journal Article] Development of a cell-based assay to identify hepatitis B virus entry inhibitors targeting the sodium taurocholate cotransporting polypeptide2018
- Author(s)
  Miyakawa Kei、Matsunaga Satoko、Yamaoka Yutaro、Dairaku Mina、Fukano Kento、Kimura Hirokazu、Chimuro Tomoyuki、Nishitsuji Hironori、Watashi Koichi、Shimotohno Kunitada、Wakita Takaji、Ryo Akihide
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 34 Pages: 23681-23694
- DOI
  10.18632/oncotarget.25348
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07161, KAKENHI-PROJECT-16K08814, KAKENHI-PROJECT-17H04085
[Journal Article] 冠Award受賞者の声平成29年度第16回MSD Award2018
- Author(s)
  渡士幸一
- Journal Title
  
  肝臓
  
  Volume: 59 Pages: 71-71
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] De Novo Macrocyclic Peptide Inhibitors of Hepatitis B Virus Cellular Entry.2018
- Author(s)
  Passioura T, Watashi K, Fukano K, Shimura S, Saso W, Morishita R, Ogasawara Y, Tanaka Y, Mizokami M, Sureau C, Suga H, Wakita T.
- Journal Title
  
  Cell Chem Biol.
  
  Volume: 25 Issue: 7 Pages: 906-915
- DOI
  10.1016/j.chembiol.2018.04.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-17H04085
[Journal Article] Rosmarinic acid is a novel inhibitor for Hepatitis B virus replication targeting viral epsilon RNA-polymerase interaction2018
- Author(s)
  Tsukamoto Yuta、Ikeda Sotaro、Uwai Koji、Taguchi Riho、Chayama Kazuaki、Sakaguchi Takemasa、Narita Ryo、Yao Wan-Ling、Takeuchi Fumihiko、Otakaki Yukie、Watashi Koichi、Wakita Takaji、Kato Hiroki、Fujita Takashi
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 5 Pages: e0197664-e0197664
- DOI
  10.1371/journal.pone.0197664
- NAID
  120006649572
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H03288, KAKENHI-PROJECT-16K01909, KAKENHI-PROJECT-17H04085
[Journal Article] IL-1β/ATF3-mediated induction of Ski2 expression enhances hepatitis B virus x mRNA degradation2018
- Author(s)
  Shiromoto Fumihiro、Aly Hussein H.、Kudo Haruka、Watashi Koichi、Murayama Asako、Watanabe Noriyuki、Zheng Xin、Kato Takanobu、Chayama Kazuaki、Muramatsu Masamichi、Wakita Takaji
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 503 Issue: 3 Pages: 1854-1860
- DOI
  10.1016/j.bbrc.2018.07.126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18F18098, KAKENHI-PROJECT-17H04085
[Journal Article] High-throughput neutralization assay for multiple flaviviruses based on single-round infectious particles using dengue virus type 1 reporter replicon.2018
- Author(s)
  Matsuda M, Yamanaka A, Yato K, Yoshii K, Watashi K, Aizaki H, Konishi E, Takasaki T, Kato T, Muramatsu M, Wakita T, Suzuki R
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 16624-16624
- DOI
  10.1038/s41598-018-34865-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03910, KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-17H04085
[Journal Article] A new strategy to identify hepatitis B virus entry inhibitors by AlphaScreen technology targeting the envelope-receptor interaction.2018
- Author(s)
  Saso W, Tsukuda S, Ohashi H, Fukano K, Morishita R, Matsunaga S, Ohki M, Ryo A, Park SY, Suzuki R, Aizaki H, Muramatsu M, Sureau C, Wakita T, Matano T, Watashi K.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 印刷中 Issue: 2 Pages: 374-379
- DOI
  10.1016/j.bbrc.2018.04.187
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19145, KAKENHI-PROJECT-18J14277, KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-17K15076, KAKENHI-PROJECT-17H04085
[Journal Article] Chemical array system, a platform to identify novel hepatitis B virus entry inhibitors targeting sodium taurocholate cotransporting polypeptide2018
- Author(s)
  Kaneko M, Futamura Y, Tsukuda S, Kondoh Y, Sekine T, Hirano H, Fukano K, Ohashi H, Saso W, Morishita R, Matsunaga S, Kawai F, Ryo A, Park S-Y, Suzuki R, Aizaki H, Ohtani N, Sureau C, Wakita T, Osada H, Watashi K
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 2769-2769
- DOI
  10.1038/s41598-018-20987-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05366, KAKENHI-PLANNED-18H05503, KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-16K19145, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-17H04085, KAKENHI-PROJECT-16H04699
[Journal Article] A new class of hepatitis B and D virus entry inhibitors, proanthocyanidin and its analogs, that directly act on the viral large surface proteins.2017
- Author(s)
  Tsukuda S, Watashi K, Hojima T, Isogawa M, Iwamoto M, Omagari K, Suzuki R, Aizaki H, Kojima S, Sugiyama M, Saito A, Tanaka Y, Mizokami M, Sureau C, Wakita T
- Journal Title
  
  Hepatology
  
  Volume: 65 Issue: 4 Pages: 1104-1116
- DOI
  10.1002/hep.28952
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15J03185, KAKENHI-PROJECT-26461015, KAKENHI-PROJECT-16K19145, KAKENHI-PROJECT-26460565
[Journal Article] 抗B型肝炎ウイルス薬の現状と新規薬剤開発のアプローチ2017
- Author(s)
  九十田千子、渡士幸一
- Journal Title
  
  化学療法の領域
  
  Volume: 33 Pages: 73-78
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] Hepatitis B virus X protein impairs α-interferon signaling via up-regulation of suppressor of cytokine signaling 3 and protein phosphatase 2A.2017
- Author(s)
  Tsunematsu S, Suda G, Yamasaki K, Kimura M, Izumi T, Umemura M, Ito J, Sato F, Nakai M, Sho T, Morikawa K, Ogawa K, Tanaka Y, Watashi K, Wakita T, Sakamoto N
- Journal Title
  
  J Med Virol
  
  Volume: 89 Issue: 2 Pages: 267-275
- DOI
  10.1002/jmv.24643
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-26461021, KAKENHI-PROJECT-16K09334, KAKENHI-PROJECT-16K15420, KAKENHI-PROJECT-26460565
[Journal Article] 抗B型肝炎ウイルス薬の現状と新規薬剤開発のアプローチ2017
- Author(s)
  九十田千子、渡士幸一
- Journal Title
  
  化学療法の領域
  
  Volume: 33 Pages: 73-78
- Data Source
  KAKENHI-PROJECT-17H04085
[Journal Article] Cyclosporin derivatives inhibit hepatitis B virus entry without interfering with NTCP transporter activity.2017
- Author(s)
  Shimura S, Watashi K, Fukano K, Peel M, Sluder A, Kawai F, Iwamoto M, Tsukuda S, Takeuchi S J, Miyake T, Sugiyama M, Ogasawara Y, Park SY, Tanaka Y, Kusuhara H, Mizokami M, Sureau C, Wakita T
- Journal Title
  
  J Hepatol
  
  Volume: 66 Issue: 4 Pages: 685-692
- DOI
  10.1016/j.jhep.2016.11.009
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15J03185, KAKENHI-PROJECT-16K19145, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-16J40232, KAKENHI-PROJECT-17K15708
[Journal Article] Revealing the characteristics of antiviral agents2017
- Author(s)
  大橋啓史、渡士幸一
- Journal Title
  
  Uirusu
  
  Volume: 67 Issue: 2 Pages: 133-142
- DOI
  10.2222/jsv.67.133
- ISSN
  0042-6857, 1884-3433
- Year and Date
  2017-12-25
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-17H04085
[Journal Article] 目覚ましいC型肝炎治療の進歩2017
- Author(s)
  渡士幸一
- Journal Title
  
  感染・炎症・免疫
  
  Volume: 47 Pages: 71-72
- Data Source
  KAKENHI-PROJECT-17H04085
[Journal Article] 目覚ましいC型肝炎治療の進歩2017
- Author(s)
  渡士幸一
- Journal Title
  
  感染炎症免疫
  
  Volume: 47 Pages: 71-72
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] Gut microbiota promotes obesity-associated liver cancer through PGE2-mediated suppression of antitumor immunity.2017
- Author(s)
  Loo TM, Kamachi F, Watanabe Y, Yoshimoto S, Kanda H, Arai Y, Nakajima-Takagi Y, Iwama A, Koga T, Sugimoto Y, Ozawa T, Nakamura M, Kumagai M, Watashi K, Taketo M, Aoki T, Narumiya S, Oshima M, Arita M, Hara E, Ohtani N.
- Journal Title
  
  Cancer Discov
  
  Volume: in press Issue: 5 Pages: 522-538
- DOI
  10.1158/2159-8290.cd-16-0932
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PLANNED-15H05905, KAKENHI-PROJECT-26250028, KAKENHI-PROJECT-14J06998, KAKENHI-PROJECT-15K12709, KAKENHI-PROJECT-15K19032, KAKENHI-PROJECT-26670030, KAKENHI-PROJECT-15K19031, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-15H04648, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-16H04699
[Journal Article] Involvement of PUF60 in Transcriptional and Post-transcriptional Regulation of Hepatitis B Virus Pregenomic RNA Expression2017
- Author(s)
  Sun Suofeng、Nakashima Kenji、Ito Masahiko、Li Yuan、Chida Takeshi、Takahashi Hirotaka、Watashi Koichi、Sawasaki Tatsuya、Wakita Takaji、Suzuki Tetsuro
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 12874-12874
- DOI
  10.1038/s41598-017-12497-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07261, KAKENHI-PROJECT-17K09447, KAKENHI-PROJECT-16K19137, KAKENHI-PLANNED-16H06579, KAKENHI-PROJECT-16H04729, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-17H04085
[Journal Article] Host factor PRPF31 is involved in cccDNA production in HBV-replicating cells2017
- Author(s)
  Kinoshita W, Ogura N, Watashi K, Wakita T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 482 Issue: 4 Pages: 638-644
- DOI
  10.1016/j.bbrc.2016.11.085
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] Quantifying antiviral activity optimizes drug combinations against hepatitis C virus infection2017
- Author(s)
  Koizumi Y, Ohashi H, Nakajima S, Tanaka Y, Wakita T, Perelson AS, Iwami S, Watashi K
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 114(8) Issue: 8 Pages: 1922-1927
- DOI
  10.1073/pnas.1610197114
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24115003, KAKENHI-PROJECT-16KT0111, KAKENHI-PROJECT-26460565
[Journal Article] 抗ウイルス薬の個性を知る～ウイルス学と数学の融合研究によるC型肝炎治療薬併用の薬効評価と最適化～2017
- Author(s)
  大橋啓史、渡士幸一
- Journal Title
  
  ウイルス
  
  Volume: 67 Pages: 133-142
- NAID
  40021454099
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] Hepatitis B virus prevents excessive viral production via reduction of cell-death inducing DFF45-like effectors2017
- Author(s)
  Yasumoto J, Kasai H, Yoshimura K, Otoguro T, Watashi K, Wakita T, Yamashita A, Tanaka T, Takeda S, Moriishi K
- Journal Title
  
  J Gen Virol
  
  Volume: NA
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] Reply to Padmanabhan and Dixit: Hepatitis C virus entry inhibitors for optimally boosting direct-acting antiviral-based treatments.2017
- Author(s)
  Ohashi HK, Koizumi Y, Fukano K, Wakita T, Perelson AS, Iwami S, Watashi K
- Journal Title
  
  Proc Acad Natl Acad USA
  
  Volume: 114 Issue: 23
- DOI
  10.1073/pnas.1705234114
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0111, KAKENHI-PROJECT-15KT0107, KAKENHI-PROJECT-17K09447, KAKENHI-PROJECT-16K13777, KAKENHI-PROJECT-16H04845, KAKENHI-PROJECT-26287025, KAKENHI-ORGANIZER-16H06429, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-17H04085
[Journal Article] ssAAVs containing cassettes encoding SaCas9 and guides targeting hepatitis B virus inactivate replication of the virus in cultured cells2017
- Author(s)
  Scott T, Moyo B, Nicholson S, Maepa MB, Watashi K, Ely A, Weinberg MS, Arbuthnot P
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 7401-7401
- DOI
  10.1038/s41598-017-07642-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-17H04085
[Journal Article] Stereo-controlled synthesis of functionalized tetrahydropyridines based on the cyanomethylation of 1,6-dihydropyridines and generation of anti-hepatitis C virus agents2017
- Author(s)
  Watanabe R, Mizoguchi H, Oikawa H, Ohashi H, Watashi K, Oguri H
- Journal Title
  
  Bioorg Med Chem
  
  Volume: NA Issue: 11 Pages: 2851-2855
- DOI
  10.1016/j.bmc.2017.03.011
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-15H03117
[Journal Article] Functional association of cellular microtubules with viral capsid assembly supports efficient hepatitis B virus replication2017
- Author(s)
  Iwamoto M、Cai D、Sugiyama M、Suzuki R、Aizaki H、Ryo A、Ohtani N、Tanaka Y、Mizokami M、Wakita T、Guo H、Watashi K
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 10620-10620
- DOI
  10.1038/s41598-017-11015-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15J03185, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-17H04085, KAKENHI-PROJECT-16H04699
[Journal Article] 抗Ｂ型肝炎ウイルス薬の現状と新規薬剤開発のアプローチ2017
- Author(s)
  九十田千子, 渡士幸一
- Journal Title
  
  化学療法の領域
  
  Volume: 33 Pages: 73-78
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] Establishment of a human hepatocellular cell line capable of maintaining long-term replication of hepatitis B virus2017
- Author(s)
  Yao WL, Ikeda S, Tsukamoto Y, Shindo K, Otakaki Y, Qin M, Iwasawa Y, Takeuchi F, Kaname Y, Chou YC, Chang C, Watashi K, Wakita T, Noda T, Kato H, Fujita T
- Journal Title
  
  Int Immunol
  
  Volume: NA Issue: 3 Pages: 109-120
- DOI
  10.1093/intimm/dxx012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] Reply to Padmanabhan and Dixit: Hepatitis C virus entry inhibitors for optimally boosting direct-acting antiviral-based treatments2017
- Author(s)
  Ohashi H, Koizumi Y, Fukano K, Wakita T, Perelson AS, Iwami S, Watashi K*
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: NA
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] Human induced-pluripotent stem cell-derived hepatocyte-like cells as an in vitro model of human hepatitis B virus infection.2017
- Author(s)
  Sakurai F, Mitani S, Yamamoto T, Takayama K, Tachibana M, Watashi K, Wakita T, Iijima S, Tanaka Y, Mizuguchi H
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 45698-45698
- DOI
  10.1038/srep45698
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17J04585, KAKENHI-PROJECT-26460565
[Journal Article] Closing the door on hepatitis B and D virus entry: what are our therapeutic options?2016
- Author(s)
  Iwamoto M and Watashi K
- Journal Title
  
  Future Virology
  
  Volume: 11 Issue: 11 Pages: 715-718
- DOI
  10.2217/fvl-2016-0097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15J03185, KAKENHI-PROJECT-26460565
[Journal Article] Hepatocyte Factor JMJD5 Regulates Hepatitis B Virus Replication through Interaction with HBx2016
- Author(s)
  Kouwaki T, Okamoto T, Ito A, Sugiyama Y, Yamashita K, Suzuki T, Kusakabe S, Hirano J, Fukuhara T, Yamashita A, Saito K, Okuzaki D, Watashi K, Sugiyama M, Yoshio S, Standley DM, Kanto T, Mizokami M, Moriishi K, Matsuura Y
- Journal Title
  
  J Virol
  
  Volume: 90 Issue: 7 Pages: 3530-3542
- DOI
  10.1128/jvi.02776-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460565, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-15K08493
[Journal Article] RNA exosome complex regulates stability of Hepatitis B Virus's X-mRNA transcript in a Non-Stop mediated (NSD) RNA quality control mechanism.2016
- Author(s)
  Hussein H. Aly, Junya Suzuki, Koichi Watashi, Kazuaki Chayama, Shin-ichi Hoshino, Makoto Hijikata, Takanobu Kato, and Takaji Wakita
- Journal Title
  
  J Biol Chem
  
  Volume: 291 Issue: 31 Pages: 15958-15974
- DOI
  10.1074/jbc.m116.724641
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25291004, KAKENHI-PROJECT-15K15293, KAKENHI-PROJECT-26460565
[Journal Article] Interferon-stimulated gene of 20KDa protein (ISG20) degrades RNA of hepatitis B virus to impede the replication of HBV in vitro and in vivo2016
- Author(s)
  Leong CR, Funami K, Oshiumi H, Mengao D, Takaki H, Matsumoto M, Ali HH, Watashi K, Chayama K, Seya T
- Journal Title
  
  Oncotarget
  
  Volume: 7 Pages: 68179-681193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] Isolation and characterization of hepatitis C virus resistant to a novel phenanthridinone derivative2016
- Author(s)
  Ito W, Toyama M, Okamoto M, Ikeda M, Watashi K, Wakita T, Hashimoto Y, Baba M
- Journal Title
  
  Antivir Chem Chemother
  
  Volume: 24 Issue: 5-6 Pages: 148-154
- DOI
  10.1177/2040206616663956
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] Human induced pluripotent stem cell-derived hepatic cell line as a new model for host interaction with hepatitis B virus.2016
- Author(s)
  Kaneko S, Kakinuma S, Asahina Y, Kamiya A, Miyoshi M, Tsunoda T, Nitta S, Asano Y, Nagata H, Otani S, Kitahata F, Murakawa M, Itsui Y, Nakagawa M, Azuma S, Nakauchi H, Iwamoto M, Watashi K, Wakita T, Sugiyama M, Mizokami M, Shimotohno K, Watanabe M.
- Journal Title
  
  Sci Rep
  
  Volume: ６ Issue: 1 Pages: 29358-29358
- DOI
  10.1038/srep29358
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05285, KAKENHI-PROJECT-26293178, KAKENHI-PROJECT-16K09345, KAKENHI-PROJECT-26460987, KAKENHI-PROJECT-15K15285, KAKENHI-PROJECT-15K19316, KAKENHI-PROJECT-15K08988, KAKENHI-PROJECT-15K08989, KAKENHI-PROJECT-26460565
[Journal Article] Prolactin Regulatory Element Binding Protein Is Involved in Hepatitis C Virus Replication by Interaction with NS4B2016
- Author(s)
  Kong L, Fujimoto A, Nakamura M, Aoyagi H, Matsuda M, Watashi K, Suzuki R, Arita M, Yamagoe S, Dohmae N, Suzuki T, Sakamaki Y, Ichinose S, Suzuki T, Wakita T, Aizaki H
- Journal Title
  
  J Virol
  
  Volume: 90 Issue: 6 Pages: 3093-3111
- DOI
  10.1128/jvi.01540-15
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-15H04735, KAKENHI-PROJECT-26670224, KAKENHI-PLANNED-24115003
[Journal Article] HBV slow maturation process leading to infection2016
- Author(s)
  Watashi K*
- Journal Title
  
  Trends Microbiol
  
  Volume: 24 Issue: 8 Pages: 597-599
- DOI
  10.1016/j.tim.2016.06.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] Anti-hepatitis C Virus Natural Product from a Fungus, Penicillium herquei2016
- Author(s)
  Nishikori S, Takemoto K, Kamisuki S, Nakajima S, Kuramochi K, Tsukuda S, Iwamoto M, Katayama Y, Suzuki T, Kobayashi S, Watashi K, Sugawara F
- Journal Title
  
  J Nat Prod
  
  Volume: 79 Issue: 2 Pages: 442-446
- DOI
  10.1021/acs.jnatprod.5b00555
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-15J03185, KAKENHI-PROJECT-15K07419
[Journal Article] B型肝炎ウイルス研究の進歩2016
- Author(s)
  渡士幸一、脇田隆字
- Journal Title
  
  Pharma Medica
  
  Volume: 34 Pages: 15-18
- Data Source
  KAKENHI-PUBLICLY-26102747
[Journal Article] B型肝炎ウイルス研究の進歩2016
- Author(s)
  渡士幸一、脇田隆字
- Journal Title
  
  Pharma Medica
  
  Volume: 34 Pages: 15-18
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] Inhibition of preS1-hepatocyte interaction by an array of recombinant human antibodies from naturally recovered individuals2016
- Author(s)
  Sankhyan A, Sharma C, Dutta D, Sharma T, Chosdol K, Wakita T, Watashi K, Awasthi A, Acharya SK, Khanna N, Tiwari A, Sinha S
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 21240-21240
- DOI
  10.1038/srep21240
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565, KAKENHI-PUBLICLY-26102747
[Journal Article] Ｂ型肝炎ウイルス研究のトピックス2016
- Author(s)
  渡士幸一, 相崎英樹
- Journal Title
  
  小児科
  
  Volume: 57 Pages: 1107-1111
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] Bivalent vaccine platform based on Japanese encephalitis virus (JEV) elicit neutralizing antibodies against JEV and hepatitis C virus2016
- Author(s)
  Saga R, Fujimoto A, Watanabe N, Matsuda M, Hasegawa M, Watashi K, Aizaki H, Nakamura N, Tajima S, Takasaki T, Konishi E, Kato T, Kohara M, Takeyama H, Wakita T, Suzuki R
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 28688-28688
- DOI
  10.1038/srep28688
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] Fatty acid biosynthesis is involved in the production of hepatitis B virus particles2016
- Author(s)
  Okamura H, Nio Y, Akahori Y, Kim S, Watashi K, Wakita T, Hijikata M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 475 Issue: 1 Pages: 87-92
- DOI
  10.1016/j.bbrc.2016.05.043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] Fungus-Derived Neoechinulin B as a Novel Antagonist of Liver X Receptor, Identified by Chemical Genetics Using a Hepatitis C Virus Cell Culture System2016
- Author(s)
  Nakajima S, Watashi K, Ohashi H, Kamisuki S, Izaguirre-Carbonell J, Kwon AT, Suzuki H, Kataoka M, Tsukuda S, Okada M, Moi ML, Takeuchi T, Arita M, Suzuki R, Aizaki H, Kato T, Suzuki T, Hasegawa H, Takasaki T, Sugawara F, Wakita T
- Journal Title
  
  J Virol
  
  Volume: 90(20) Issue: 20 Pages: 9058-74
- DOI
  10.1128/jvi.00856-16
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24115003, KAKENHI-PROJECT-16K19145, KAKENHI-PROJECT-26460565
[Journal Article] Single-domain Intrabodies against HCV Core Inhibit Viral Propagation and Core-induced NF-κB Activation2016
- Author(s)
  Suzuki R, Saito K, Matsuda M, Sato M, Kanegae Y, Shi G, Watashi K, Aizaki H, Chiba J, Saito I, Wakita T, Suzuki T
- Journal Title
  
  J Gen Virol
  
  Volume: 印刷中 Issue: 4 Pages: 887-892
- DOI
  10.1099/jgv.0.000423
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24115003, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-15H04735, KAKENHI-PROJECT-26670221, KAKENHI-PROJECT-26670224, KAKENHI-PROJECT-25293134, KAKENHI-PROJECT-26460565
[Journal Article] HBVの細胞内侵入機構とこれを標的とした創薬2015
- Author(s)
  渡士幸一
- Journal Title
  
  日本臨床
  
  Volume: 73増刊号9 Pages: 372-376
- Data Source
  KAKENHI-PUBLICLY-26102747
[Journal Article] HBV/HDV entry, species specificity and tissue tropism2015
- Author(s)
  Watashi K, Wakita T
- Journal Title
  
  Cold Spring Harb Perspect Med
  
  Volume: N/A
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26102747
[Journal Article] B型肝炎ウイルスエントリーについて：メカニズムとその阻害2015
- Author(s)
  渡士幸一、脇田隆字
- Journal Title
  
  肝胆膵
  
  Volume: 71 Pages: 1053-1058
- Data Source
  KAKENHI-PUBLICLY-26102747
[Journal Article] HBV/HDV entry, species specificity and tissue tropism2015
- Author(s)
  Watashi K, Wakita T
- Journal Title
  
  Cold Spring Harb Perspect Med
  
  Volume: N/A
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] Hepatitis B Virus and Hepatitis D Virus Entry, Species Specificity, and Tissue Tropism2015
- Author(s)
  Watashi K, Wakita T
- Journal Title
  
  Cold Spring Harb Perspect Med
  
  Volume: 5 Issue: 8 Pages: a021378-a021378
- DOI
  10.1101/cshperspect.a021378
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460565, KAKENHI-PUBLICLY-26102747
[Journal Article] Isolation and structure of vanitaracin A, a novel anti-hepatitis B virus compound from Talaromyces sp2015
- Author(s)
  Matsunaga H, Kamisuki S, Kaneko M, Yamaguchi Y, Takeuchi T, Watashi K, Sugawara F
- Journal Title
  
  Bioorg Med Chem Lett
  
  Volume: 25 Issue: 19 Pages: 4325-4328
- DOI
  10.1016/j.bmcl.2015.07.067
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460565, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-15K07419
[Journal Article] Molecular dissection of HBV evasion from restriction factor tetherin: A new perspective for antiviral cell therapy2015
- Author(s)
  Miyakawa K, Matsunaga S, Watashi K, Sugiyama M, Kimura H, Yamamoto N, Mizokami M, Wakita T, Ryo A
- Journal Title
  
  Oncotarget
  
  Volume: 6 Pages: 21840-21852
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-26102747
[Journal Article] HBVの細胞内侵入機構とこれを標的とした創薬2015
- Author(s)
  渡士幸一
- Journal Title
  
  日本臨床
  
  Volume: 73増刊号9 Pages: 372-376
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] B型肝炎ウイルスエントリーについて：メカニズムとその阻害2015
- Author(s)
  渡士幸一、脇田隆字
- Journal Title
  
  肝胆膵
  
  Volume: 71 Pages: 1053-1058
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] A Novel Tricyclic Polyketide, Vanitaracin A, Specifically Inhibits the Entry of Hepatitis B and D Viruses by Targeting Sodium Taurocholate Cotransporting Polypeptide2015
- Author(s)
  Kaneko M, Watashi K, Kamisuki S, Matsunaga H, Iwamoto M, Kawai F, Ohashi H, Tsukuda S, Shimura S, Suzuki R, Aizaki H, Sugiyama M, Park SY, Ito T, Ohtani N, Sugawara F, Tanaka Y, Mizokami M, Sureau C, Wakita T
- Journal Title
  
  J Virol
  
  Volume: 89 Issue: 23 Pages: 11945-11953
- DOI
  10.1128/jvi.01855-15
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565, KAKENHI-ORGANIZER-24115001, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-15J03185, KAKENHI-PROJECT-15K07419, KAKENHI-PROJECT-25291016
[Journal Article] 新規B型肝炎抗ウイルス薬開発の現状2015
- Author(s)
  渡士幸一、脇田隆字
- Journal Title
  
  カレントテラピー
  
  Volume: 33 Pages: 903-907
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] Disparity of basal and therapeutically activated interferon signalling in constraining hepatitis E virus infection2015
- Author(s)
  Zhou X, Xu L, Wang W, Watashi K, Wang Y, Sprengers D, de Ruiter PE, van der Laan LJ, Metselaar HJ, Kamar N, Peppelenbosch MP, Pan Q
- Journal Title
  
  J Viral Hepat
  
  Volume: 23 Issue: 4 Pages: 294-304
- DOI
  10.1111/jvh.12491
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-26460565
[Journal Article] Molecular dissection of HBV evasion from restriction factor tetherin: A new perspective for antiviral cell therapy2015
- Author(s)
  Miyakawa K, Matsunaga S, Watashi K, Sugiyama M, Kimura H, Yamamoto N, Mizokami M, Wakita T, Ryo A
- Journal Title
  
  Oncotarget
  
  Volume: 6 Pages: 21840-21852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] Hepatitis B virus efficiently infects non-adherent hepatoma cells via human sodium taurocholate cotransporting polypeptide.2015
- Author(s)
  Okuyama-Dobashi K, Kasai H, Tanaka T, Yamashita A, Yasumoto J, Chen W, Okamoto T, Maekawa S, Watashi K, Wakita T, Ryo A, Suzuki T, Matsuura Y, Enomoto N, Moriishi K.
- Journal Title
  
  Scientific reports
  
  Volume: 5 Issue: 1 Pages: 17047-17047
- DOI
  10.1038/srep17047
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08493, KAKENHI-PROJECT-26460565, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-15H04735, KAKENHI-PROJECT-25460985
[Journal Article] Identification of antiviral agents targeting hepatitis B virus promoter from extracts of Indonesian marine organisms by a novel cell-based screening assay.2015
- Author(s)
  Yamashita A, Fujimoto Y, Tamaki M, Setiawan A, Tanaka T, Okuyama-Dobashi K, Kasai H, Watashi K, Wakita T, Toyama M, Baba M, de Voogd NJ, Maekawa S, Enomoto N, Tanaka J, Moriishi K
- Journal Title
  
  Marine Drug
  
  Volume: 13 Issue: 11 Pages: 6759-6773
- DOI
  10.3390/md13116759
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08493, KAKENHI-PROJECT-26350973, KAKENHI-PROJECT-26460565, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-25460985
[Journal Article] Amino acid polymorphisms in hepatitis C virus core affect infectious virus production and major histocompatibility complex class I molecule expression2015
- Author(s)
  Tasaka-Fujita M, Sugiyama N, Kang W, Masaki T, Murayama A, Yamada N, Sugiyama R, Tsukuda S, Watashi K, Asahina Y, Sakamoto N, Wakita T, Shin EC, Kato T
- Journal Title
  
  Sci Rep
  
  Volume: 5 Issue: 1 Pages: 13994-14002
- DOI
  10.1038/srep13994
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09035, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-15K15285, KAKENHI-PROJECT-26860309, KAKENHI-PLANNED-24115003, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-26670375, KAKENHI-PROJECT-25293169
[Journal Article] 新規B型肝炎抗ウイルス薬開発の現状2015
- Author(s)
  渡士幸一、脇田隆字
- Journal Title
  
  カレントテラピー
  
  Volume: 33 Pages: 903-907
- Data Source
  KAKENHI-PUBLICLY-26102747
[Journal Article] 第6章　抗ウイルス薬2015
- Author(s)
  渡士幸一
- Journal Title
  
  生命科学のためのウイルス学
  
  Volume: N/A Pages: 143-176
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] The RNA Sensor RIG-I Dually Functions as an Innate Sensor and Direct Antiviral Factor for Hepatitis B Virus2015
- Author(s)
  Sato S, Li K, Kameyama T, Hayashi T, Ishida Y, Murakami S, Watanabe T, Iijima S, Sakurai Y, Watashi K, Tsutsumi S, Sato Y, Akita H, Wakita T, Rice CM, Harashima H, Kohara M, Tanaka Y, Takaoka A
- Journal Title
  
  Immunity
  
  Volume: 42 Issue: 1 Pages: 123-132
- DOI
  10.1016/j.immuni.2014.12.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390117, KAKENHI-PUBLICLY-25114712, KAKENHI-PROJECT-25253030, KAKENHI-PROJECT-25870015, KAKENHI-PROJECT-25893001, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-26893001
[Journal Article] Novel Robust in Vitro Hepatitis B Virus Infection Model Using Fresh Human Hepatocytes Isolated from Humanized Mice.2015
- Author(s)
  Ishida Y, Yamasaki C, Yanagi A, Yoshizane Y, Fujikawa K, Watashi K, Abe H, Wakita T, Hayes CN, Chayama K, Tateno C.
- Journal Title
  
  Am J Pathol.
  
  Volume: 185 Issue: 5 Pages: 1275-1285
- DOI
  10.1016/j.ajpath.2015.01.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26420796, KAKENHI-PROJECT-26460565, KAKENHI-PUBLICLY-26102747
[Journal Article] Dysregulation of retinoic acid receptor diminishes hepatocyte permissiveness to hepatitis B virus infection through modulation of sodium taurocholate cotransporting polypeptide (NTCP) expression.2015
- Author(s)
  Tsukuda S, Watashi K, Iwamoto M, Suzuki R, Aizaki H, Okada M, Sugiyama M, Kojima S, Tanaka Y, Mizokami M, Li J, Tong S, Wakita T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 290 Issue: 9 Pages: 5673-84
- DOI
  10.1074/jbc.m114.602540
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860574, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-26460565, KAKENHI-PUBLICLY-26102741, KAKENHI-PUBLICLY-26102742
[Journal Article] Formation of covalently closed circular DNA in Hep38.7-Tet cells, a tetracycline inducible hepatitis B virus expression cell line2014
- Author(s)
  Ogura N, Watashi K, Noguchi T, Wakita T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 452(3) Issue: 3 Pages: 315-321
- DOI
  10.1016/j.bbrc.2014.08.029
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-26460565
[Journal Article] Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter, sodium taurocholate cotransporting polypeptide (NTCP)2014
- Author(s)
  Watashi K, Sluder A, Daito T, Matsunaga S, Ryo A, Nagamori S, Iwamoto M, Nakajima S, Tsukuda S, Borroto-Esoda K, Sugiyama M, Tanaka Y, Kanai Y, Kusuhara H, Mizokami M, Wakita T
- Journal Title
  
  Hepatology
  
  Volume: 59 Issue: 5 Pages: 1726-1737
- DOI
  10.1002/hep.26982
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390117, KAKENHI-PUBLICLY-24102537, KAKENHI-ORGANIZER-24115001, KAKENHI-PROJECT-24390217, KAKENHI-PROJECT-24591198, KAKENHI-PUBLICLY-25136714, KAKENHI-PROJECT-25860574
[Journal Article] B型肝炎ウイルス感染を抑制するサイトカインの同定とその分子メカニズムの解析2014
- Author(s)
  渡士幸一
- Journal Title
  
  Liver Forum in Kyoto 第16回学術集会記録集
  
  Volume: N/A Pages: 13-17
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] Production of single-round infectious chimeric flaviviruses with DNA-based Japanese encephalitis virus replicon2014
- Author(s)
  Suzuki R, Ishikawa T, Konishi E, Matsuda M, Watashi K, Aizaki H, Takasaki T, Wakita T
- Journal Title
  
  J Gen Virol
  
  Volume: 95 Issue: 1 Pages: 60-65
- DOI
  10.1099/vir.0.058008-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-24102537, KAKENHI-PLANNED-24115003, KAKENHI-PROJECT-24590563, KAKENHI-PROJECT-24591001
[Journal Article] Alternative endocytosis pathway for productive entry of hepatitis C virus.2014
- Author(s)
  Matsuda M, Suzuki R, Kataoka C, Watashi K, Aizaki H, Kato N, Matsuura Y, Suzuki T, Wakita T
- Journal Title
  
  J Gen Virol.
  
  Volume: 95(Pt 12) Issue: 12 Pages: 2658-67
- DOI
  10.1099/vir.0.068528-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24115003, KAKENHI-PROJECT-24390111, KAKENHI-PROJECT-24591001, KAKENHI-PROJECT-25860832, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-26670224, KAKENHI-PROJECT-25293110, KAKENHI-PROJECT-25293134
[Journal Article] 肝炎の基礎　HBV感染生活環と培養系2014
- Author(s)
  渡士幸一
- Journal Title
  
  肝疾患review 2014-2015
  
  Volume: N/A Pages: 20-26
- Data Source
  KAKENHI-PROJECT-26460565
[Journal Article] Evaluation and identification of hepatitis B virus entry inhibitors using HepG2 cells overexpressing a membrane transporter NTCP2014
- Author(s)
  Iwamoto M, Watashi K, Tsukuda S, Aly HH, Fukasawa M, Fujimoto A, Suzuki R, Aizaki H, Ito T, Koiwai O, Kusuhara H, Wakita T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 443 Issue: 3 Pages: 808-813
- DOI
  10.1016/j.bbrc.2013.12.052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-24102537, KAKENHI-PROJECT-24591001
[Journal Article] NTCP and beyond : opening the door to unveil hepatitis B virus entry2014
- Author(s)
  Watashi K, Urban S, Li W, Wakita T.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 15 Pages: 2892-2905
- Data Source
  KAKENHI-PROJECT-23790514
[Journal Article] NTCP and beyond: opening the door to unveil hepatitis B virus entry2014
- Author(s)
  Watashi K, Urban S, Li W, Wakita T
- Journal Title
  
  Int J Mol Sci
  
  Volume: 15 Issue: 2 Pages: 2892-2905
- DOI
  10.3390/ijms15022892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790514, KAKENHI-PUBLICLY-24102537
[Journal Article] 肝炎の基礎　HBV感染生活環と培養系2014
- Author(s)
  渡士幸一
- Journal Title
  
  肝疾患review 2014-2015
  
  Volume: N/A Pages: 20-26
- Data Source
  KAKENHI-PUBLICLY-26102747
[Journal Article] Production of single-round infectious chimeric flaviviruses with DNA-based Japanese encephalitis virus replicon2014
- Author(s)
  Suzuki R, Ishikawa T, Konishi E, Matsuda M, Watashi K, Aizaki H, Takasaki T, Wakita T
- Journal Title
  
  J Gen Virol
  
  Volume: 95 Pt 1 Pages: 60-65
- Data Source
  KAKENHI-PROJECT-23790514
[Journal Article] NTCP transporter as novel target for anti-hepatitis B virus agents2014
- Author(s)
  Tsukuda S, Watashi K.
- Journal Title
  
  Clin Res Infect Dis
  
  Volume: 1
- Data Source
  KAKENHI-PROJECT-23790514
[Journal Article] Evaluation and identification of hepatitis B virus entry inhibitors using HepG2 cells overexpressing a membrane transporter NTCP2014
- Author(s)
  Iwamoto M, Watashi K, Tsukuda S, Aly HH, Fukasawa M, Fujimoto A, Suzuki R, Aizaki H, Ito T, Koiwai O, Kusuhara H, Wakita T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 443 Pages: 808-813
- Data Source
  KAKENHI-PROJECT-23790514
[Journal Article] Cyclophilin Inhibitors Reduce Phosphorylation of RNA-dependent Protein Kinase to Restore Expression of IFN-stimulated Genes in HCV-infected Cells.2014
- Author(s)
  Daito T, Watashi K, Sluder A, Ohashi H, Nakajima S, Borroto-Esoda K, Fujita T, Wakita T.
- Journal Title
  
  Gastroenterology
  
  Volume: 147(2) Issue: 2 Pages: 463-72
- DOI
  10.1053/j.gastro.2014.04.035
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24115003, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-26460565
[Journal Article] B型肝炎ウイルス感染を抑制するサイトカインの同定とその分子メカニズムの解析2014
- Author(s)
  渡士幸一
- Journal Title
  
  Liver Forum in Kyoto 第16回学術集会記録集
  
  Volume: N/A Pages: 13-17
- Data Source
  KAKENHI-PUBLICLY-26102747
[Journal Article] 第6章　抗ウイルス薬2014
- Author(s)
  渡士幸一
- Journal Title
  
  生命科学のためのウイルス学
  
  Volume: N/A Pages: 143-176
- Data Source
  KAKENHI-PUBLICLY-26102747
[Journal Article] Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter NTCP2014
- Author(s)
  Watashi K, Sluder A, Daito T, Matsunaga S, Ryo A, Nagamori S, Iwamoto M, Nakajima S, Tsukuda S, Borroto-Esoda K, Sugiyama M, Tanaka Y, Kanai Y, Kusuhara H, Mizokami M, Wakita T.
- Journal Title
  
  Hepatology
  
  Volume: 59 Pages: 1726-1737
- Data Source
  KAKENHI-PROJECT-23790514
[Journal Article] Specific inhibition of hepatitis C virus entry into host hepatocytes by fungi-derived sulochrin and its derivatives2013
- Author(s)
  Nakajima S, Watashi K, Kamisuki S, Tsukuda S, Takemoto K, Matsuda M, Suzuki R, Aizaki H, Sugawara F, Wakita T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 440(4) Issue: 4 Pages: 515-20
- DOI
  10.1016/j.bbrc.2013.09.100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659407, KAKENHI-PUBLICLY-24102537, KAKENHI-ORGANIZER-24115001, KAKENHI-PLANNED-24115003
[Journal Article] 薬学的視点からのウイルス学研究―肝炎ウイルス複製阻害化合物の同定とその作用機序2013
- Author(s)
  渡士幸一
- Journal Title
  
  薬学雑誌
  
  Volume: 133 Pages: 1169-1175
- NAID
  130003382269
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24102537
[Journal Article] Antiviral activity of glycyrrhizin against hepatitis C virus in vitro2013
- Author(s)
  Matsumoto Y, Matsuura T, Aoyagi H, Matsuda M, Hmwe SS, Date T, Watanabe N, Watashi K, Suzuki R, Ichinose S, Wake K, Suzuki T, Miyamura T, Wakita T, Aizaki H
- Journal Title
  
  PLoS One
  
  Volume: 8
- Data Source
  KAKENHI-PROJECT-23790514
[Journal Article] Specific inhibition of hepatitis C virus entry into host hepatocytes by fungi-derived sulochrin and its derivatives2013
- Author(s)
  Nakajima S, Watashi K, Kamisuki S, Tsukuda S, Takemoto K, Matsuda M, Suzuki R, Aizaki H, Sugawara F, Wakita T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 440 Pages: 515-520
- Data Source
  KAKENHI-PROJECT-23790514
[Journal Article] Total Synthesis and Anti-Hepatitis C Virus Activity of MA0262013
- Author(s)
  Shimura S, Ishima M, Nakajima S, Fujii T, Himeno N, Ikeda K, Izaguirre-Carbonell J, Murata H, Takeuchi T, Kamisuki S, Suzuki T, Kuramochi K, Watashi K, Kobayashi S, Sugawara F
- Journal Title
  
  J Am Chem Soc
  
  Volume: 135 Pages: 18949-18956
- Data Source
  KAKENHI-PROJECT-23790514
[Journal Article] Interleukin-1 and tumor necrosis factor-α trigger restriction of hepatitis B virus infection via a cytidine deaminase activation-induced cytidine deaminase (AID)2013
- Author(s)
  Watashi K, Liang G, Iwamoto M, Marusawa H, Uchida N, Daito T, Kitamura K, Muramatsu M, Ohashi H, Kiyohara T, Suzuki R, Li J, Tong S, Tanaka Y, Murata K, Aizaki H, Wakita T
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Issue: 44 Pages: 31715-31727
- DOI
  10.1074/jbc.m113.501122
- NAID
  120006602140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790514, KAKENHI-PROJECT-23790780, KAKENHI-PUBLICLY-24102537, KAKENHI-PLANNED-24115003, KAKENHI-PROJECT-24590563
[Journal Article] 薬学的視点からのウイルス学研究-肝炎ウイルス複製阻害化合物の同定とその作用機序-2013
- Author(s)
  渡士幸一
- Journal Title
  
  薬学雑誌
  
  Volume: 133 Pages: 1169-1175
- NAID
  130003382269
- Data Source
  KAKENHI-PROJECT-23790514
[Journal Article] 薬学的視点からのウイルス学研究―肝炎ウイルス複製阻害化合物の同定とその作用機序2013
- Author(s)
  渡士幸一
- Journal Title
  
  薬学雑誌
  
  Volume: 133 Pages: 1169-1175
- NAID
  130003382269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790514
[Journal Article] Antiviral activity of glycyrrhizin against hepatitis C virus in vitro2013
- Author(s)
  Matsumoto Y, Matsuura T, Aoyagi H, Matsuda M, Hmwe SS, Date T, Watanabe N, Watashi K, Suzuki R, Ichinose S, Wake K, Suzuki T, Miyamura T, Wakita T, Aizaki H
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 7 Pages: e68992-e68992
- DOI
  10.1371/journal.pone.0068992
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24102537, KAKENHI-PLANNED-24115003, KAKENHI-PROJECT-24390111
[Journal Article] Signal peptidase complex subunit 1 participates in the assembly of hepatitis C virus through an interaction with E2 and NS22013
- Author(s)
  Suzuki R, Matsuda M, Watashi K, Aizaki H, Matsuura Y, Wakita T, Suzuki T
- Journal Title
  
  PLoS Pathog
  
  Volume: 9 Issue: 8 Pages: 1-12
- DOI
  10.1371/journal.ppat.1003589
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24102537, KAKENHI-ORGANIZER-24115001, KAKENHI-PLANNED-24115003, KAKENHI-PROJECT-24390111, KAKENHI-PROJECT-24390113, KAKENHI-PROJECT-24590563, KAKENHI-PUBLICLY-25115511
[Journal Article] Interleukin-1 and tumor necrosis factor-αtrigger restriction of hepatitis B virus infection via a cytidine deaminase activation-induced cytidine deaminase (AID)2013
- Author(s)
  Watashi K, Liang G, Iwamoto M, Marusawa H, Uchida N, Daito T, Kitamura K, Muramatsu M, Ohashi H, Kiyohara T, Suzuki R, Li J, Tong S, Tanaka Y, Murata K, Aizaki H, Wakita T.
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Pages: 31715-31727
- NAID
  120006602140
- Data Source
  KAKENHI-PROJECT-23790514
[Journal Article] Signal peptidase complex subunit 1 participates in the assembly of hepatitis C virus through an interaction with E2 and NS22013
- Author(s)
  Suzuki R, Matsuda M, Watashi K, Aizaki H, Matsuura Y, Wakita T, Suzuki T
- Journal Title
  
  PLoS Pathog
  
  Volume: 9
- Data Source
  KAKENHI-PROJECT-23790514
[Journal Article] Total synthesis and anti-hepatitis C virus activity of MA0262013
- Author(s)
  Shimura S, Ishima M, Nakajima S, Fujii T, Himeno N, Ikeda K, Izaguirre-Carbonell J, Murata H, Takeuchi T, Kamisuki S, Suzuki T, Kuramochi K, Watashi K, Kobayashi S, Sugawara F
- Journal Title
  
  J Am Chem Soc
  
  Volume: 135 Issue: 50 Pages: 18949-18956
- DOI
  10.1021/ja410145x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790514, KAKENHI-PUBLICLY-24102537
[Journal Article] HBV培養細胞系による新規抗ウイルス化合物のスクリーニング2012
- Author(s)
  渡士幸一
- Journal Title
  
  肝胆膵
  
  Volume: 65 Pages: 611-617
- Data Source
  KAKENHI-PROJECT-23790514
[Journal Article] Different mechanisms of hepatitis C virus RNA polymerase activation by cyclophilin A and B in vitro2012
- Author(s)
  Weng L, Tian X, Gao Y, Watashi K, Shimotohno K, Wakita T, Kohara M, Toyoda T
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1820 Pages: 1886-1892
- Data Source
  KAKENHI-PROJECT-23790514
[Journal Article] Japanese reference panel of blood specimens for evaluation of hepatitis C virus RNA and core antigen quantitative assays2012
- Author(s)
  Murayama A, Sugiyama N, Watashi K, Masaki T, Suzuki R, Aizaki H, Mizuochi T, Wakita T, Kato T
- Journal Title
  
  J Clin Microbiol
  
  Volume: 50 Pages: 1943-1949
- Data Source
  KAKENHI-PROJECT-23790514
[Journal Article] Japanese reference panel of blood specimens for evaluation of hepatitis C virus RNA and core antigen quantitative assays.2012
- Author(s)
  Maruyama, A.
- Journal Title
  
  J. Clin. Microbiol.
  
  Volume: 50(6) Issue: 6 Pages: 1943-1949
- DOI
  10.1128/jcm.00487-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390202, KAKENHI-PROJECT-23790513, KAKENHI-PROJECT-23790514, KAKENHI-PUBLICLY-24102537
[Journal Article] Cyclosporin A associated helicase-like protein facilitates the association of hepatitis C virus RNA polymerase with its cellular cyclophilin B2011
- Author(s)
  Morohashi K+, Sahara H, Watashi K+, Iwabata K, Sunoki T, Kuramochi K, Takakusagi K, Miyashita H, Sato N, Tanabe A, Shimotohno K, Kobayashi S, Sakaguchi K, Sugawara F. (+equally contributed)
- Journal Title
  
  PLoS One
  
  Volume: 6
- Data Source
  KAKENHI-PROJECT-23790514
[Journal Article] Cyclosporin A Associated Helicase-Like Protein Facilitates the Association of Hepatitis C Virus RNA Polymerase with Its Cellular Cyclophilin B2011
- Author(s)
  諸橋謙吾、佐原広益、小林進、坂口謙吾、菅原二三男
- Journal Title
  
  PLoS ONE
  
  Volume: 6 Issue: 4 Pages: 18285-18285
- DOI
  10.1371/journal.pone.0018285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390004, KAKENHI-PROJECT-22710219, KAKENHI-PROJECT-23790514
[Journal Article] Potent and selective inhibition of hepatitis C virus replication by novel phenanthridinone derivatives2011
- Author(s)
  Salim MT, Aoyama H, Sugita K, Watashi K, Wakita T, Hamasaki T, Okamoto M, Urata Y, Hashimoto Y, Baba M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 415 Pages: 714-719
- Data Source
  KAKENHI-PROJECT-23790514
[Journal Article] Different mechanisms of hepatitis C virus RNA polymerase activation by cyclophilin A and B in vitro2011
- Author(s)
  Weng L, Tian X, shimotohno K, et al.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1820 Issue: 12 Pages: 1886-1892
- DOI
  10.1016/j.bbagen.2012.08.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249012, KAKENHI-PROJECT-23659238, KAKENHI-PROJECT-24390117, KAKENHI-PUBLICLY-23114511, KAKENHI-PUBLICLY-24102537
[Journal Article] Cyclophilin and viruses ; cyclophilin as a cofactor for viral infection and possible anti-viral target.2007
- Author(s)
  Watashi K. et al.
- Journal Title
  
  Drug Target Insights. 1
  
  Pages: 9-18
- Data Source
  KAKENHI-PROJECT-17790306
[Journal Article] 抗HCV剤候補探索の現状とそれを用いたHCV複製機構の解析2005
- Author(s)
  渡士幸一ら
- Journal Title
  
  ウイルス 55(1)
  
  Pages: 105-110
- NAID
  10016449680
- Data Source
  KAKENHI-PROJECT-17790306
[Journal Article] Cyclophilin B is a funetional regulator of hepatitis C virus RNA polymerase2005
- Author(s)
  Watashi K et al.
- Journal Title
  
  Mol.Cell 19(1)
  
  Pages: 111-122
- Data Source
  KAKENHI-PROJECT-17790306
[Journal Article] HCV増殖のメカニズムとその抑制2005
- Author(s)
  渡士幸一ら
- Journal Title
  
  C型肝炎ウイルスと生体肝移植
  
  Pages: 20-23
- Data Source
  KAKENHI-PROJECT-17790306
[Journal Article] Chemical genetics approach to hepatitis C virus replication : cyclophilin as a target for anti-hepatitis C virus strategy.
- Author(s)
  Watashi K. et al.
- Journal Title
  
  Rev.Med.Virol. (in press)
- Data Source
  KAKENHI-PROJECT-17790306
[Patent] HBV感染阻害剤2019
- Inventor(s)
  渡士幸一、脇田隆字、村松正道
- Industrial Property Rights Holder
  渡士幸一、脇田隆字、村松正道
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-033601
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17H04085
[Patent] NTCPを標的とした抗B型肝炎ウイルス剤2018
- Inventor(s)
  菅裕明、トビーパシオウラ、脇田隆字、渡士幸一
- Industrial Property Rights Holder
  菅裕明、トビーパシオウラ、脇田隆字、渡士幸一
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-002814
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] 胆汁酸トランスポーターNTCPによるB型肝炎ウイルス認識の構造基盤2023
- Author(s)
  浅見仁太*、朴在鉉、野村弥生、石本直偉士*、小林ちさ*、御舩淳紀、植村智子、劉紅、佐藤有美、村松正道、脇田隆字、Drew David、渡士幸一、岩田想、清水敏之、朴三用、野村紀通、大戸梅治
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-23K27415
[Presentation] NTCP/SLC10A1 の胆汁酸取り込み機能に影響しない選択的B型肝炎ウイルス侵入阻害ペプチドの同定2019
- Author(s)
  深野顕人, Toby PASSIOURA, 志村聡美, 佐宗若奈, 森下了, 小笠原裕樹, 田中靖人, 溝上雅史, Camille SUREAU, 脇田隆字, 菅裕明, 渡士幸一
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] B型肝炎ウイルス培養系と薬剤開発への応用2019
- Author(s)
  渡士幸一
- Organizer
  京都大学ウイルス・再生医科学研究所再生医学・再生医療の先端融合的共同研究拠点ウイルス感染症・生命科学先端融合的共同研究拠点平成30年度共同研究合同報告会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] B型肝炎ウイルス侵入に関わる宿主因子の同定と作用機序解析2018
- Author(s)
  Wakana Saso, Masashi Iwamoto, Masamichi Muramatsu, Tetsuro Matano, Koichi Watashi
- Organizer
  第15回ウイルス学キャンプin湯河原
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] HBVエントリー阻害剤Tomatineの同定と抗HBV活性の解析2018
- Author(s)
  古谷裕, 戸口真理子, 佐藤裕美, 九十田千子, 渡士幸一, 湯川博, 石川哲也, 黒田俊一, 上田啓次, 田中靖人, 脇田隆字, 小嶋聡一
- Organizer
  第28回抗ウイルス療法学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] RNA granule components regulate HBV replication2018
- Author(s)
  Yasuo Ariumi, Koichi Watashi, Mikinori Ueno, Lin Deng, Hak Hotta, Takaji Wakita
- Organizer
  2018 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Identification of novel HBV entry inhibitors by in vitro technologies2018
- Author(s)
  Koichi Watashi
- Organizer
  6th Taiwan-Japan-Korea HBV Research Symposium 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Flavivirus subviral particles-based DNA vaccine induces neutralizing antibodies against HCV2018
- Author(s)
  Yato K, Matsuda M, Watanabe N, Nakajima S, Fujimoto A, Watashi K, Aizaki H, Kato T, Muramatsu M, Wakita T, Suzuki R
- Organizer
  25th International Symposium on Hepatitis C Virus and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Oligomerization of NTCP induces hepatitis B virus internalization2018
- Author(s)
  Kento Fukano, Senko Tsukuda, Mio Ohki, Sam-Yong Park, Ryosuke Suzuki, Hideki Aizaki, Masamichi Muramatsu, Takaji Wakita, Yuki Ogasawara, Koichi Watashi
- Organizer
  2018 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Isolation and structure determination of antiviral natural products from fungi2018
- Author(s)
  Kamisuki S, Matsunaga H, Nishikori S, Takemoto K, Kaneko M, Nakajima S, Murakami M, Murakami H, Kuramochi K, Watashi K, Sugawara F
- Organizer
  American Society of Pharmacognosy 2018 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Hepatitis C virus infection triggers the transactivation of aryl hydrocarbon receptor to rearrange hepatic lipid biosynthesis2018
- Author(s)
  Ohashi H, Nakajima S, Kim S, Suzuki R, Aizaki H, Fukasawa M, Kamisuki S, Sugawara F, Ohtani N, Muramatsu M, Wakita T, Watashi K
- Organizer
  The 66th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] HCV genome and abnomal oraganelles in the liver after elimination of hepatitis C virus by drug treatment2018
- Author(s)
  Aizaki H, Aoyagi H, Iijima H, Zheng X, Matsuda M, Watashi K, Suzuki R, Masaki T, Shimada N, Kato K, Tsubota A, Saito T, Hayashi K, Enomoto M, Mimata A, Sakamaki Y, Ichinose S, Wakae K, Muramatsu M, Wakita T
- Organizer
  The 66th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] IL-1b/ATF3 mediated regulation of HBx mRNA decay2018
- Author(s)
  Aly HH, Watashi K, Watanabe N, Wakita T
- Organizer
  The 66th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Bardoxolon methyl suppresses the prolifieration of both hepatitis B and C viruses in culture cells2018
- Author(s)
  Akahori Y, Okamura H, Sasaki M, Hasegawa H, Watashi K, Wakita T, Tanaka Y, Nio Y, Hijikata M
- Organizer
  The 66th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Establishment of a model for the quantification of hepatitis B virus cccDNA dynamics2018
- Author(s)
  Kakizoe Y, Iwamoto M, Davenport MP, Watashi K, Iwami S
- Organizer
  The 66th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Novel predictors of the treatment outcome of Hepatitis B patients treated with entecavir and lamivudine nucleos(t)ide analogues2018
- Author(s)
  Alexey Martyushev, Shingo Iwami, Koichi Watashi
- Organizer
  2018 Annual Meeting of the Society for Mathematical Biology & the Japanese Society for Mathematical Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Cell entry inhibition as an antiviral strategy2018
- Author(s)
  Koichi Watashi
- Organizer
  2018 APASL Single Topic Conference on Hepatitis B Virus (2018 APASL STC Taipei)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] B型肝炎ウイルス培養系の構築から創薬研究へ2018
- Author(s)
  渡士幸一
- Organizer
  日本薬学会第138年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Anti-HBV activity of novel pyrimidotriazinone derivatives through the inhibition of viral nucleocapsid assembly2018
- Author(s)
  Masaaki Toyama, Norikazu Sakakibara, Mika Okamoto, Masanori Ikeda, Koichi Watashi, Takaji Wakita, Masanori Baba
- Organizer
  2018 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Mechanistical study of antiviral activity of snake venom sPLA2 against HBV and HCV2018
- Author(s)
  Miyayama Y, Chen M, Aoki-Utsubo C, Deng L, Shindo K, Noda T, Kohara M, Watashi K, Wakita T, Hijikata M, Hotta H
- Organizer
  The 66th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Interaction of host and hepatitis viruses as a target for drug development2018
- Author(s)
  Koichi Watashi
- Organizer
  Taiwan Society of Virology, Symposium in Memory of Dr. Kuan-Teh Jeang: Human Retrovirus and Hepatitis virus
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Antiviral activity of phospholipase A2 group V (PLA2G5) against HCV2018
- Author(s)
  Puig-Basagoiti F, Fukasawa M, Suzuki R, Watashi K, Muramatsu M, Wakita T, Aizaki H
- Organizer
  25th International Symposium on Hepatitis C Virus and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Drug screening for suppression of lipogenesis through downregulation of C/EBPa2018
- Author(s)
  Satoh S, Onomura D, Watashi K, Ueda Y, Dansako H, Honda M, Kaneko S, Kato N
- Organizer
  The 66th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Acidic polysaccharides isolated from marine algae, ascophyllan and fucoidans, inhibit the early step of hepatitis B virus infection2018
- Author(s)
  Mikinori Ueno, Masato Nogawa, Rokeya Siddiqui, Koichi Watashi, Takaji Wakita, Takasi Okimura, Shogo Isaka, Tatsuya Oda, Yasuo Ariumi
- Organizer
  2018 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] AlphaScreen assay targeting the NTCP-large surface antigen interaction identified rapamycin and its derivatives as novel hepatitis B virus entry inhibitors2018
- Author(s)
  Wakana Saso, Senko Tsukuda, Hirofumi Ohashi, Kento Fukano, Ryo Morishita, Satoko Matsunaga, Mio Ohki, Akihide Ryo, Sam-Yong Park, Ryosuke Suzuki, Hideki Aizaki, Masamichi Muramatsu, Camille Sureau, Takaji Wakita, Tetsuro Matano, Koichi Watashi
- Organizer
  2018 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Generation of monocloneal antibodies against hepatitis B virus preS1 region from antigen-specific memory B cells2018
- Author(s)
  Yato K, Onodera T, Matsuda M, Fujimoto A, Watashi K, Aizaki H, Kato T, Moriishi K, Tamura K, Takahashi Y, Wakita T, Muramatsu M, Suzuki R
- Organizer
  The 66th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Comparative analysis of antiviral activity of sPLA2 against HBV and HCV2018
- Author(s)
  Hak Hotta, Ming Chen, Chie Aoki-Utsubo, Lin Deng, Yohei Miyayama, Makoto Hijikata, Keiko Shindo, Takeshi Noda, Michinori Kohara, Koichi Watashi, Takaji Wakita
- Organizer
  2018 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Ultrastructure of hepatocytes in chronic hepatitis B patients2018
- Author(s)
  Haruyo Aoyagi, Hiroki Iijima, Xin Zheng, Yu Ting Kao, Koichi Watashi, Ryosuke Suzuki, Noritomo Shimada, Keizo Kato, Akihito Tsubota, Ayako Mimata, Yuriko Sakamaki, Shizuko Ichinose, Kenjiro Wake, Masamichi Muramatsu, Takaji Wakita, Hideki Aizaki
- Organizer
  2018 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Abnormal hepatocellular organelles remain to be observed in sustained virological response (SVR) patients2018
- Author(s)
  Aoyagi H, Iijima H, Zheng X, Kao YT, Matsuda M, Watashi K, Suzuki R, Masaki T, Shimada N, Kato K, Tsubota A, Wake K, Wakita T, Aizaki H
- Organizer
  25th International Symposium on Hepatitis C Virus and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Identification of host kinases that regulate hepatitis B virus internalization2018
- Author(s)
  Iwamoto M, Saso W, Sugiyama M, Ishii K, Suzuki R, Aizaki H, Ryo A, Ohtani N, Muramatsu M, Iwami S, Tanaka Y, Wakita T, Watashi K
- Organizer
  The 66th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Acidic polysaccharides isolated from marine algae, ascophyllan and fucoidans, inhibit the early step pf hepatits B virus infection2018
- Author(s)
  Ueno M, Nogawa M, Siddiqui R, Watashi K, Wakita T, Okimura T, Isaka S, Oda T, Ariumi Y
- Organizer
  The 66th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] ウイルス-脂質相互作用に関わる核内受容体の解析2018
- Author(s)
  Kazane Nishioka, Hirofumi Ohashi, Ryosuke Suzuki, Hideki Aizaki, Masamichi Muramatsu, Takaji Wakita, Koichi Watashi
- Organizer
  第15回ウイルス学キャンプin湯河原
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] AlphaScreen technology targeting the viral envelope-receptor interaction identified a novel HBV entry inhibitor, rapamycin2018
- Author(s)
  Saso W, Tsukuda S, Ohashi H, Fukano K, Morishita R, Matsunaga S, Ohki M, Ryo A, Park S, Suzuki R, Aizaki H, Muramatsu M, Wakita T, Matano T, Watashi K
- Organizer
  The 66th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] SLC10A1/NTCPのトラフィッキング制御を標的とした新規B型肝炎ウイルス感染阻害戦略2018
- Author(s)
  深野顕人, 九十田千子, 鈴木亮介, 相崎英樹, 村松正道, 脇田隆字, 小笠原裕樹, 渡士幸一
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] D型肝炎ウイルス生存戦略の理解と意義について2018
- Author(s)
  岩本将士, 岩見真吾, 渡士幸一
- Organizer
  第15回ウイルス学キャンプin湯河原
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] B型肝炎ウイルス侵入阻害ペプチドの同定とその機序の解析2018
- Author(s)
  深野顕人、Passioura Toby、志村聡美、佐宗若奈、森下了、小笠原裕樹、田中靖人、溝上雅史、Sureau Camille、菅裕明、脇田隆字、渡士幸一
- Organizer
  第15回ウイルス学キャンプin湯河原
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Aryl hydrocarbon receptor-cytochrome p450 1a1 pathway regulates hepatic lipid biosynthesis to maximize Hepatitis C virus production2018
- Author(s)
  Ohashi H, Nakajima S, Kim S, Suzuki R, Aizaki H, Fukasawa M, Kamisuki S, Sugawara F, Ohtani N, Muramatsu M, Wakita T, Watashi K
- Organizer
  25th International Symposium on Hepatitis C Virus and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Oligomerization of NTCP is required for hepatitis B virus internalization2018
- Author(s)
  Fukano K, Tsukuda S, Ohki M, Park S, Suzuki R, Aizaki H, Muramatsu M, Wakita T, Ogasawara Y, Watashi K
- Organizer
  The 66th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Interaction between nuclear factor-erythroid 2 related factor 2 and hepatitis B virus2018
- Author(s)
  Yohei Miyayama, Hitomi Okamura, Machiko Sasai, Yuichi Akahori, Koichi Watashi, Takaji Wakita, Makoto Hijikata
- Organizer
  2018 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] B型肝炎ウイルスの創薬研究2018
- Author(s)
  脇田隆字, 渡士幸一
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Engineering of HBV-specific SynNotch receptor to estabilsh biosensor cells2018
- Author(s)
  Satoko Matsunaga, Kei Miyakawa, Sayaka Shizukuishi, Koichi Watashi, Takaji Wakita, Akihide Ryo
- Organizer
  2018 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Identification of aryl hydrocarbon receptor ligands inhibiting the lipid accumulation and hepatitis C virus production2018
- Author(s)
  Nishioka K, Ohashi H, Suzuki R, Aizaki H, Muramatsu M, Wakita T, Watashi K
- Organizer
  The 66th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Rosmarinic acid is a novel inhibitor for Hepatitis B virus replication targeting viral epsilon RNA-polymerase binding2018
- Author(s)
  Yuta Tsukamoto, Sotaro Ikeda, Koji Uwai, Riho Taguchi, Kazuaki Chayama, Takemasa Sakaguchi, Ryo Narita, Wan-Ling Yao, Fumihiko Takeuchi, Yukie Otakaki, Koichi Watashi, Takaji Wakita, Hiroki Kato, Takashi Fujita
- Organizer
  2018 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] 培養細胞系を利用した HBV cccDNA ダイナミクスの定量的検討2018
- Author(s)
  渡士幸一, 九十田千子, 脇田隆字
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Clinical and Virological Significance of NTCP Receptor in HBV2018
- Author(s)
  Koichi Watashi
- Organizer
  2018 APASL Single Topic Conference on Hepatitis B Virus (2018 APASL STC Taipei)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Retrotransposon elements are among initial sites of HBV integration into human genome in HBV-HepG2-NTCP cell infection model2018
- Author(s)
  Thomas Michalak, Ranjit Chauhan, Yoshimi Shimizu, Koichi Watashi, Takaji Wakita, Masayoshi Fukasawa
- Organizer
  2018 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Identification of Aryl hydrocarbon receptor ligands inhibiting the lipid accumulation and Hepatitis C virus production2018
- Author(s)
  Nishioka K, Ohashi H, Suzuki R, Aizaki H, Muramatsu M, Wakita T, Watashi K
- Organizer
  25th International Symposium on Hepatitis C Virus and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] A comparison between HCV JFH-1 and Jc1 strains by quantitative analysis of infection dynamics2018
- Author(s)
  Iwanani S, Ohashi H, Asai Y, Watashi K, Iwami S
- Organizer
  The 66th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] 核内受容体を利用した肝炎ウイルス増殖戦略2018
- Author(s)
  渡士幸一
- Organizer
  日本大学医学部セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] スフィンゴ脂質のC型肝炎ウイルス複製における役割の解析2018
- Author(s)
  相崎英樹, ホッサムゲワイド, 青柳東代, Zheng Xin, Fransec Puig-Basagoiti, 渡士幸一, 鈴木亮介, 熊谷圭悟, 山地俊之, 深澤征義, 酒巻有里子, 花田賢太郎, 村松正道, 脇田隆字
- Organizer
  第28回抗ウイルス療法学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Identification of HBV entry inhibitors without interfering with the NTCP transporter activity2017
- Author(s)
  Fukano K, Shimura S, Peel M, Sluder A, Kawai F, Tsukuda S, Suzuki R, Aizaki H, Park SY, Wakita T, Ogasawara Y, Watashi K
- Organizer
  5th JAPAN-TAIWAN-KOREA HBV Research Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Crosstalk of Xenobiotic Metabolism Pathway with Lipid Metabolism regulates the Host Permissiveness to Hepatitis C Virus Production2017
- Author(s)
  Hirofumi Ohashi, Syo Nakajima, Sulyi Kim, Ryosuke Suzuki, Hideki Aizaki, Masayoshi Fukasawa, Shinji Kamisuki, Fumio Sugawara, Naoko Ohtani, Takaji Wakita, Koichi Watashi
- Organizer
  第14回ウイルス学キャンプin湯河原
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] An Epidemiology Study of Acute Hepatitis B in Japan, April 1999 ~ December 20152017
- Author(s)
  Zheng X, Aoyagi H, Hossam G, Zaitsu T, Puig-Basagoiti F, Kao Y, Watashi K, Suzuki R, Takahashi T, Sunagawa T, Oishi K, Wakita T, Aizaki H
- Organizer
  2017 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Screening of FDA-approved drugs activating cyclic GMP-AMP synthase promoter2017
- Author(s)
  Imai H, Dansako H, Ueda Y, Satoh S, Watashi K, Wakita T, Kato N
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] B型肝炎ウイルスの培養系と創薬研究2017
- Author(s)
  渡士幸一
- Organizer
  第１９回仙台 Liver Meeting
- Invited
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] C型慢性肝炎のウイルス学的著効（SVR）後の肝実質細胞のオルガネラ異常の解析2017
- Author(s)
  青柳東代, 飯島尋子, Francesc Puig-Basagoiti, Zheng Xin, Yu Ting Kao, Gewaid E. Hossam, 在津拓馬, 松田麻未, 渡士幸一, 鈴木亮介, 政木隆博, 島田紀明, 加藤慶三, 坪田昭人, 三又絢子, 酒巻有里子, 市野瀬志津子, 和氣健二郎, 脇田隆字, 相崎英樹
- Organizer
  第27回抗ウイルス療法学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Membrane protein, embryonic lethal, abnormal vision, drosophila-like 1, interacts with NS5A and involves in hepatitis C virus replication2017
- Author(s)
  Kao YT, Goto K, Aoyagi H, Hossam GE, Zheng X, Puig-Basagoiti F, Watashi K, Suzuki R, Yamagoe S, Dohmae N, Suzuki T, Okushin K, Tsutsumi T, Yotsuyanagi H, Moriya K, Koike K, Suzuki T, Wakita T, Aizaki H
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 培養細胞を用いたB型肝炎ウイルス cccDNAノ動態解析2017
- Author(s)
  Masashi Iwamoto, Yusuke Kakizoe, Shingo Iwami, Koichi Watashi
- Organizer
  第14回ウイルス学キャンプin湯河原
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Analysis of HBV life cycle in the HepG2 expressing human NTCP cell line2017
- Author(s)
  Rahayu R, Ohsaki E, Honda T, Okamoto T, Watashi K, Ueda K
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] NTCPを利用したHBV創薬研究およびNTCPを介したHBV侵入機構の解析2017
- Author(s)
  九十田千子、渡士幸一、小嶋聡一、脇田隆字
- Organizer
  2017年度生命科学系合同年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] The integrity of cellular microtubule structure is important for an efficient HBV capsid formation2017
- Author(s)
  Iwamoto M, Cai D, Sugiyama M, Suzuki R, Aizaki H, Ryo A, Ohtani N, Tanaka Y, Mizokami M, Wakita T, Guo H, Watashi K
- Organizer
  2017 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] B型肝炎ウイルス培養系を用いた創薬研究2017
- Author(s)
  渡士幸一、九十田千子、脇田隆字
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Modulation of HBV life cycle by sulforaphane2017
- Author(s)
  Okamura H, Sasai M, Nio Y, Watashi K, Wakita T, Hijikata M
- Organizer
  2017 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Modulation of HBV life cycle by sulforaphane2017
- Author(s)
  Okamura H, Sasai M, Nio Y, Watashi K, Wakita T, Hijikata M
- Organizer
  2017 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] B型肝炎ウイルス培養系の構築から創薬研究へ2017
- Author(s)
  渡士幸一
- Organizer
  日本薬学会第138年会
- Invited
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Supporting evidence that HBV virions bud mainly through the ER/ERGIC membranes2017
- Author(s)
  Hotta H, Chen M, Aoki-Utsubo C, Deng L, Watashi K, Wakita T
- Organizer
  2017 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] トランスポーターと肝炎ウイルス2017
- Author(s)
  渡士幸一
- Organizer
  日本薬物動態学会第32回年会東京
- Invited
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Generation of hepatitis C virus vaccine antigen based on Japanese encephalitis virus subviral particles2017
- Author(s)
  Yato K, Matsuda M, Watanabe N, Nakajima S, Fujimoto A, Watashi K, Aizaki H, Kato T, Tamura K, Wakita T, Suzuki R
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] 1999年から2015年までの日本におけるB型急性肝炎4273症例の疫学解析2017
- Author(s)
  Zheng Xin, 青柳東代, Gewaid E. Hossam, 在津拓馬, Puig-Basagoiti Francesc, Yu Ting Kao, 渡士幸一, 鈴木亮介, 高橋琢理, 砂川富正, 大石和徳, 脇田隆字. 相崎英樹
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Involvement of cell-death inducing DFF45-like effectors in HBV replication2017
- Author(s)
  Yasumoto J, Kasai H, Yoshimura K, Otoguro T, Watashi K, Wakita T, Yamashita A, Tanaka T, Takeda S, Moriishi K
- Organizer
  5th JAPAN-TAIWAN-KOREA HBV Research Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Acute hepatitis C virus infection among HIV-infected men who have sex with men2017
- Author(s)
  Aoyagi H, Itoda I, Zheng X, Gewaid HE, Puig-Basagoiti F, Kao YT, Watashi K, Suzuki R, Wakita T, Aizaki H
- Organizer
  APASL Single Topic Conference 2017 Mongolia 6th HCV Conference on HCV and co-infections
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] B型肝炎ウイルスの内在化阻害剤の同定2017
- Author(s)
  Fukano K, Tsukuda S, Suzuki R, Aizaki H, Wakita T, Ogasawara Y, Watashi K
- Organizer
  第14回ウイルス学キャンプin湯河原
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Ultrastructure of hepatocytes in chronic hepatitis C patients who achieve a sustained virological response2017
- Author(s)
  Aoyagi H, Iijima H, Puig-Basagoiti F, Zheng X, Kao YT, Hossam GE, Zaitsu T, Matsuda M, Watashi K, Suzuki R, Masaki T, Shimada N, Kato K, Tsubota A, Mimata A, Sakamaki Y, Ichinose S, Wake K, Wakita T, Aizaki H
- Organizer
  The 26th of Conference of Asian Pacific Association for the Study of the Liver, ANNUAL MEETING 2017
- Place of Presentation
  上海
- Year and Date
  2017-02-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] NTCPを利用したHBV創薬研究およびNTCPを介したHBV侵入機構の解析2017
- Author(s)
  九十田千子, 渡士幸一, 小嶋聡一, 脇田隆字
- Organizer
  2017年度生命科学系合同年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 抗HBV効果を有するNeplanocin A誘導体の作用機序解析2017
- Author(s)
  外山政明, 濱崎隆之, 岡本実佳, 渡士幸一, 脇田隆字, Ashoke Sharon, 馬場昌範
- Organizer
  第27回抗ウイルス療法学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] B型肝炎ウイルスの培養系と創薬研究2017
- Author(s)
  渡士幸一
- Organizer
  第１９回仙台 Liver Meeting
- Invited
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Identification of a new class of HBV and HDV entry inhibitor, proanthocyanidin2017
- Author(s)
  Senko Tsukuda, Koichi Watashi, Soichi Kojima, Takaji Wakita
- Organizer
  AASLD The Liver Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Ｂ型肝炎ウイルス基礎研究・創薬研究の最近の知見2017
- Author(s)
  渡士幸一
- Organizer
  衛生微生物技術協議会第38回研究会
- Invited
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 抗肝炎ウイルス薬の薬効・変異頻度定量評価系の開発と多剤併用の意義2017
- Author(s)
  渡士幸一, 小泉吉輝, 大橋啓史, 中嶋翔, 田中靖人, 脇田隆字, Alan S. Perelson, 岩見真吾
- Organizer
  第27回抗ウイルス療法学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Targeting HBV-X by regulating Non-Stop mediated RNA decay2017
- Author(s)
  Hussein H. Aly, Fumihiro Shiromoto, Takanobu Kato, Koichi Watashi, Kazuaki Chayama, Takaji Wakita
- Organizer
  5th JAPAN-TAIWAN-KOREA HBV Research Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] HBV exploit Ski2/RNA complex to degrade cytokines and suppress inflammation2017
- Author(s)
  Aly HH, Shiromoto F, Watashi K, Kato T, Chayama K, Wakita T
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] B型肝炎ウイルス培養系を用いた創薬研究2017
- Author(s)
  渡士幸一、九十田千子、脇田隆字
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Interaction of hepatitis B virus core protein with microtubles is important for the efficient capsid formation2017
- Author(s)
  Iwamoto M, Cai D, Sugiyama M, Suzuki R, Aizaki H, Ryo A, Ohtani N, Tanaka Y, Mizokami M, Wakita T, Watashi K
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] HBV-X and the balance between degradation or inflammation2017
- Author(s)
  Aly HH, Shiromoto F, Watashi K, Hoshino S, Kato T, Chayama K, Wakita T
- Organizer
  2017 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Novel Crosstalk of Xenobiotic Response with Lipid Metabolism Regulates the Host Permissiveness to Hepatitis C Virus Production2017
- Author(s)
  Ohashi H, Nakajima S, Kim S, Suzuki R, Aizaki H, Fukasawa M, Kamisuki S, Sugawara F, Ohtani N, Wakita T, Watashi K
- Organizer
  24th International Symposium on Hepatitis C Virus and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Human hepatic stellate cells are permissive for hepatitis C virus infection/replication and play important roles in fibrosis2017
- Author(s)
  Zheng X, Zaitsu T, Aoyagi H, Matsuda M, Watanabe N, Fujimoto A, Watashi K, Suzuki R, Fukuhara T, Matsuura Y, Ichinose S, Wake K, Suzuki T, Iijima H, Yokoyama H, Masaki T, Matsuura T, Tamura K, Wakita T, Aizaki H
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Acute Hepatitis B in Japan, April 1999 ~ December 20152017
- Author(s)
  Zheng X, Aoyagi H, Hossam G, Zaitsu T, Puig-Basagoiti F, Kao Y, Watashi K, Suzuki R, Takahashi T, Sunagawa T, Oishi K, Wakita T, Aizaki H
- Organizer
  5th JAPAN-TAIWAN-KOREA HBV Research Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Structural Proteins of Hepatitis C virus Genotype 3a S310 Strain Permit Claudin-1- independent Entry2017
- Author(s)
  Suzuki R, Yato K, Tosaka T, Hmwe SS, Matsuda M, Watashi K, Aizaki H, Fukasawa M, Matsuura Y, Wakita T
- Organizer
  24th International Symposium on Hepatitis C Virus and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 生理活性化合物を利用した肝炎ウイルス生活環の解析2017
- Author(s)
  渡士幸一
- Organizer
  国立成育医療研究センターセミナ-
- Invited
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] 50.Fatty acids synthesized from cellular fatty acid synthesis pathway play roles in hepatitis B virus production2017
- Author(s)
  Okamura H, Nio Y, Watashi K, Wakita T, Hijikata M
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Sphingomyelin participates in the formation of Hepatitis C virus membrane replication vesicles2017
- Author(s)
  Hossam E. GEWAID, Haruyo AOYAGI, Minetaro ARITA, Koichi WATASHI, Ryosuke SUZUKI, Hussein ALY, Keigo KUMAJAI, Toshiyuki YAMAJI, Masayoshi FUKASAWA, Ayako MIMATA, Yuriko SAKAMAKI, Shizuko ICHINOSE, Kentaro HANADA, Takaji WAKITA, Hideki AIZAKI
- Organizer
  American Society for Virology - 2017 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Establishment of a neutralization assay for multiple flaviviruses based on single-round infectious particles2017
- Author(s)
  Matsuda M, Yamanaka A, Yoshii K, Watashi K, Aizaki H, Konishi E, Takasaki T, Wakita T, Suzuki R
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Interaction of hepatitis B virus core protein with microtubles is important for the efficient capsid formation2017
- Author(s)
  Iwamoto M, Cai D, Sugiyama M, Suzuki R, Aizaki H, Ryo A, Ohtani N, Tanaka Y, Mizokami M, Wakita T, Watashi K
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Broad antiviral activities of acidic polysaccharides isolated from marine algae2017
- Author(s)
  Ueno M, Nogawa M, Siddiqui R, Watashi K, Wakita T, Kato T, Oda T, Ariumi Y
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Identification of a hepatitis B virus internalization inhibitor with a novel mode of action2017
- Author(s)
  Fukano K, Tsukuda S, Suzuki R, Aizaki H, Wakita T, Ogasawara Y, Watashi K
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Abnormal hepatocellular organelles remain to be observed in sustained virological response patients2017
- Author(s)
  Aoyagi H, Iijima H, Puig-Basagoiti F, Zheng X, Kao YT, Hossam GE, Matsuda M, Watashi K, Suzuki R, Masaki T, Aizawa N, Shimada N, Kato K, Tsubota A, Mimata A, Sakamaki Y, Ichinose S, Wake K, Wakita T, Aizaki H
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] The integrity of cellular microtubule structure is important for an efficient HBV capsid formation2017
- Author(s)
  Iwamoto M, Cai D, Sugiyama M, Suzuki R, Aizaki H, Ryo A, Ohtani N, Tanaka Y, Mizokami M, Wakita T, Guo H, Watashi K
- Organizer
  2017 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Supporting evidence that HBV virions bud mainly through the ER/ERGIC membranes2017
- Author(s)
  Hotta H, Chen M, Aoki-Utsubo C, Deng L, Watashi K, Wakita T
- Organizer
  2017 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] ヒトiPS細胞由来肝細胞のB型肝炎ウイルス in vitro 感染評価系への応用2017
- Author(s)
  三谷成二, 櫻井文教, 山本達郎, 高山和雄, 立花雅史, 渡士幸一, 脇田隆字, 飯島沙幸, 田中靖人, 水口裕之
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Membrane protein, embryonic lethal, abnormal vision, drosophila-like 1, interacts with NS5A and involves in hepatitis C virus replication2017
- Author(s)
  Kao YT, Goto K, Aoyagi H, Hossam GE, Zheng X, Puig-Basagoiti F, Watashi K, Suzuki R, Yamagoe S, Dohmae N, Suzuki T, Okushin K, Tsutsumi T, Yotsuyanagi H, Moriya K, Koike K, Suzuki T, Wakita T, Aizaki H
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Structural Proteins of Hepatitis C virus Genotype 3a S310 Strain Permit Claudin-1- independent Entry2017
- Author(s)
  Suzuki R, Yato K, Tosaka T, Hmwe SS, Matsuda M, Watashi K, Aizaki H, Fukasawa M, Matsuura Y, Wakita T
- Organizer
  24th International Symposium on Hepatitis C Virus and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Abnormal organelles were continuously observed in sustained virological response (SVR) patients2017
- Author(s)
  Haruyo Aoyagi, Hiroko Iijima, Francesc Puig-Basagoiti, Zheng Xin, Yu　Ting Kao, Gewaid E. Hossam, Takuma Zaitsu, Mami Matsuda, Koichi Watashi, Ryosuke Suzuki, Takahiro Masaki, Noritomo Shimada, Keizo Kato, Akihito Tsubota, Ayako Mimata, Yuriko Sakamaki, Shizuko Ichinose, Kenjiro Wake, Takaji Wakita, Hideki Aizaki
- Organizer
  The Asian Pacific Associaton for the Study of the Liver - Single Topic Conference 2017 Nagasaki
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] HCVの肝星細胞への感染および肝星細胞活性化のメカニズム解析2017
- Author(s)
  相崎英樹、渡士幸一、鈴木哲朗、政木隆博、横山寛、脇田隆字
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] 抗肝炎ウイルス薬の薬効・変異頻度定量評価系の開発と多剤併用の意義2017
- Author(s)
  渡士幸一, 小泉吉輝, 大橋啓史, 中嶋翔, 田中靖人, 脇田隆字, Alan S. Perelson, 岩見真吾
- Organizer
  第27回抗ウイルス療法学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Phosphorylation of protein kinase R and translational suppression by NS5B protein of hepatitis C virus2017
- Author(s)
  Suzuki R, Matsuda M, Shimoike T, Watashi K, Aizaki H, Kato T, Suzuki T, Wakita T
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Identification of a hepatitis B virus internalization inhibitor with a novel mode of action2017
- Author(s)
  Fukano K, Tsukuda S, Suzuki R, Aizaki H, Wakita T, Ogasawara Y, Watashi K
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Hepatitis B virus capsid formation is regulated by microtubules and their posttranslational modification2017
- Author(s)
  Iwamoto M, Sugiyama M, Suzuki R, Aizaki H, Tanaka Y, Mizokami M, Ohtani N, Wakita T, Watashi K
- Organizer
  5th JAPAN-TAIWAN-KOREA HBV Research Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Identification of a new class of HBV and HDV entry inhibitor, proanthocyanidin2017
- Author(s)
  Tsukuda S, Watashi K, Kojima S, Wakita T
- Organizer
  AASLD The Liver Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Antiviral effect of bile acid derivatives on hepatitis B virus infection2017
- Author(s)
  Okumura A, Ito K, Watashi K, Takeuchi J, Inoue R, Suzuki S, Sakamoto K, Okutsu S, Umezawa K, Wakita T, Yoneda M
- Organizer
  2017 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Involvement of cell-death inducing DFF45-like effectors in HBV replication2017
- Author(s)
  Jun Yasumoto, Hirotake Kasai, Kentaro Yoshimura, Teruhime Otoguro, Koichi Watashi, Takaji Wakita, Atsuya Yamashita, Tomohisa Tanaka, Sen Takeda, Kohji Moriishi
- Organizer
  5th JAPAN-TAIWAN-KOREA HBV Research Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] B型肝炎ウイルスの内在化阻害剤の同定2017
- Author(s)
  Kento Fukano, Senko Tsukuda, Ryosuke Suzuki, Hideki Aizaki, Takaji Wakita, Yuki Ogasawara, Koichi Watashi
- Organizer
  第14回ウイルス学キャンプin湯河原
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] 培養細胞を用いたB型肝炎ウイルス cccDNAの動態解析2017
- Author(s)
  Iwamoto M, Kakizoe Y, Iwami S, Watashi K
- Organizer
  第14回ウイルス学キャンプin湯河原
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Hepatitis B virus capsid formation is regulated by microtubules and their posttranslational modification2017
- Author(s)
  Masashi Iwamoto, Masaya Sugiyama, Ryosuke Suzuki, Hideki Aizaki, Yasuhito Tanaka, Masashi Mizokami, Naoko Ohtani, Takaji Wakita, Koichi Watashi
- Organizer
  5th JAPAN-TAIWAN-KOREA HBV Research Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Fatty acids with certain carbon chain length can support hepatitis B virus production2017
- Author(s)
  Okamura H, Nio Y, Watashi K, Wakita T, Hijikata M
- Organizer
  2017 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Broad antiviral activities of acidic polysaccharides isolated from marine algae2017
- Author(s)
  Ueno M, Nogawa M, Siddiqui R, Watashi K, Wakita T, Kato T, Oda T, Ariumi Y
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Novel crosstalk of Xenobiotic Response with Lipid Biosynthesis Pathway regulates the Host Permissiveness to the Hepatitis C Virus Production2017
- Author(s)
  Ohashi H, Nakajima S, Kim S, Fukasawa M, Suzuki R, Aizaki H, Sugawara F, Ohtani N, Wakita T, Watashi K
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] B型肝炎ウイルスの侵入受容体の解析とその新規阻害剤の同定2017
- Author(s)
  深野顕人, 志村聡美, Michael PEEL, Ann SLUDER, 河合文啓, 九十田千子, 鈴木亮介, 相崎英樹, 朴三用, 脇田隆字, 小笠原裕樹, 渡士幸一
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] HCVの肝星細胞への感染および肝星細胞活性化のメカニズム解析2017
- Author(s)
  相崎英樹、渡士幸一、鈴木哲朗、政木隆博、横山寛、脇田隆字
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Acute Hepatitis B in Japan, April 1999 ~ December 20152017
- Author(s)
  Zheng X, Aoyagi H, Hossam GE, Zaitsu T, Puig-Basagoiti F, Kao YT, Watashi K, Suzuki R, Takahashi T, Sunagawa T, Oishi K, Wakita T, Aizaki H
- Organizer
  The 26th of Conference of Asian Pacific Association for the Study of the Liver, ANNUAL MEETING 2017
- Place of Presentation
  上海
- Year and Date
  2017-02-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] An Epidemiology Study of Acute Hepatitis B in Japan, April 1999 ~ December 20152017
- Author(s)
  Zheng X, Aoyagi H, Hossam G, Zaitsu T, Puig-Basagoiti F, Kao Y, Watashi K, Suzuki R, Takahashi T, Sunagawa T, Oishi K, Wakita T, Aizaki H
- Organizer
  2017 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 胆汁酸代謝調節機構を標的としたB型肝炎ウイルス制御の試み2017
- Author(s)
  伊藤清顕、渡士幸一、米田政志
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Chemical array system for identifying anti-hepatitis B virus entry inhibitors2017
- Author(s)
  九十田千子, 金子学, 渡士幸一, 小嶋聡一, 脇田隆字
- Organizer
  第14回ウイルス学キャンプin湯河原
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Establishment of quantification method for the efficacy of anti-hepatitis virus combination treatments2017
- Author(s)
  Watashi K, Koizumi Y, Ohashi H, Nakajima S, Tanaka Y, Wakita T, Perelson AS, Iwami S
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] SLC10A1/NTCPのトラフィッキング制御を標的とした新規B型肝炎ウイルス感染阻害戦略2017
- Author(s)
  深野顕人, 九十田千子, 鈴木亮介, 相崎英樹, 村松正道, 脇田隆字, 小笠原裕樹, 渡士幸一
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] NS5A-Associated Membrane Protein, Embryonic Lethal, Abnormal Vision, Drosophila-Like 1, Involves in Hepatitis C Replication2017
- Author(s)
  Kao YT, Goto K, Aoyagi H, Hossam GE, Zheng X, Puig-Basagoiti F, Watashi K, Suzuki R, Yamagoe S, Dohmae N, Suzuki T, Okushin K, Tsutsumi T, Yotsuyanagi H, Moriya K, Koike K, Suzuki T, Wakita T, Aizaki H
- Organizer
  24th International Symposium on Hepatitis C Virus and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Sphingomyelin participates in the formation of Hepatitis C virus membrane replication vesicles2017
- Author(s)
  Gewaid HE, Aoyagi H, Arita M, Watashi K, Suzuki R, Aly HH, Kumagai K, Yamaji T, Fukasawa M, Mimata A, Sakamaki Y, Ichinose S, Hanada K, Wakita T, Aizaki H
- Organizer
  American Society for Virology - 2017 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] C型慢性肝炎のウイルス学的著効（SVR）後の肝実質細胞のオルガネラ異常の解析2017
- Author(s)
  青柳東代, 飯島尋子, Francesc Puig-Basagoiti, Zheng Xin, Yu Ting Kao, Gewaid E. Hossam, 在津拓馬, 松田麻未, 渡士幸一, 鈴木亮介, 政木隆博, 島田紀明, 加藤慶三, 坪田昭人, 三又絢子, 酒巻有里子, 市野瀬志津子, 和氣健二郎, 脇田隆字, 相崎英樹
- Organizer
  第27回抗ウイルス療法学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Identification of HBV entry inhibitors without interfering with the NTCP transporter activity2017
- Author(s)
  Kento Fukano, Satomi Shimura, Michael Peel, Ann Sluder, Fumihiro Kawai, Senko Tsukuda, Ryosuke Suzuki, Hideki Aizaki, Sam-Yong Park, Takaji Wakita, Yuki Ogasawara, Koichi Watashi
- Organizer
  5th JAPAN-TAIWAN-KOREA HBV Research Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Fatty acids synthesized from cellular fatty acid synthesis pathway play roles in hepatitis B virus production2017
- Author(s)
  Okamura H, Nio Y, Watashi K, Wakita T, Hijikata M
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Fatty acids with certain carbon chain length can support hepatitis B virus production2017
- Author(s)
  Okamura H, Nio Y, Watashi K, Wakita T, Hijikata M
- Organizer
  2017 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Novel Crosstalk of Xenobiotic Response with Lipid Metabolism Regulates the Host Permissivenessto Hepatitis C Virus Production2017
- Author(s)
  Ohashi H, Nakajima S, Kim S, Suzuki R, Aizaki H, Fukasawa M, Kamisuki S, Sugawara F, Ohtani N, Wakita T, Watashi K
- Organizer
  24th International Symposium on Hepatitis C Virus and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Establishment of quantification method for the efficacy of anti-hepatitis virus combination treatments2017
- Author(s)
  Watashi K, Koizumi Y, Ohashi H, Nakajima S, Tanaka Y, Wakita T, Perelson AS, Iwami S
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Ｂ型肝炎ウイルス基礎研究・創薬研究の最近の知見2017
- Author(s)
  渡士幸一
- Organizer
  衛生微生物技術協議会第38回研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] HBV-X and the balance between degradation or inflammation2017
- Author(s)
  Aly H, Shiromoto F Watashi K, Hoshino S, Kato T, Chayama K, Wakita T
- Organizer
  2017 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Phosphorylation of protein kinase R and translational suppression by NS5B protein of hepatitis C virus2017
- Author(s)
  Suzuki R, Matsuda M, Shimoike T, Watashi K, Aizaki H, Kato T, Suzuki T, Wakita T
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Screening of FDA-approved drugs activating cyclic GMP-AMP synthase promoter2017
- Author(s)
  Imai H, Dansako H, Ueda Y, Satoh S, Watashi K, Wakita T, Kato N
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] トランスポーターと肝炎ウイルス2017
- Author(s)
  渡士幸一
- Organizer
  日本薬物動態学会第32回年会
- Invited
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Generation of hepatitis C virus vaccine antigen based on Japanese encephalitis virus subviral particles2017
- Author(s)
  Yato K, Matsuda M, Watanabe N, Nakajima S, Fujimoto A, Watashi K, Aizaki H, Kato T, Tamura K, Wakita T, Suzuki R
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Chemical array system for identifying anti-hepatitis B virus entry inhibitors2017
- Author(s)
  九十田千子、金子学、渡士幸一、小嶋聡一、脇田隆字
- Organizer
  第14回ウイルス学キャンプin湯河原
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Establishment of a neutralization assay for multiple flaviviruses based on single-round infectious particles2017
- Author(s)
  Matsuda M, Yamanaka A, Yoshii K, Watashi K, Aizaki H, Konishi E, Takasaki T, Wakita T, Suzuki R
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Abnormal organelles were continuously observed in sustained virological response (SVR) patients2017
- Author(s)
  Aoyagi H, Iijima H, Puig-Basagoiti F, Zheng X, Kao YT, Gewaid HE, Zaitsu T, Matsuda M, Watashi K, Suzuki R, Masaki T, Shimada N, Kato K, Tsubota A, Mimata A, Sakamaki Y, Ichinose S, Wake K, Wakita T, Aizaki H
- Organizer
  The Asian Pacific Associaton for the Study of the Liver - Single Topic Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 肝細胞内脂肪滴および脂質膜構造によるC型肝炎ウイルス増殖制御機構の解析2017
- Author(s)
  渡士幸一
- Organizer
  第２８回小野医学研究財団　研究成果発表会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] 抗HBV効果を有するNeplanocin A誘導体の作用機序解析2017
- Author(s)
  外山政明, 濱崎隆之, 岡本実佳, 渡士幸一, 脇田隆字, Ashoke Sharon, 馬場昌範
- Organizer
  第27回抗ウイルス療法学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Human hepatic stellate cells are permissive for hepatitis C virus infection/replication and play important roles in fibrosis2017
- Author(s)
  Zheng X, Zaitsu T, Aoyagi H, Matsuda M, Watanabe N, Fujimoto A, Watashi K, Suzuki R, Fukuhara T, Matsuura Y, Ichinose S, Wake K, Suzuki T, Iijima H, Yokoyama H, Masaki T, Matsuura T, Tamura K, Wakita T, Aizaki H
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] NS5A-Associated Membrane Protein, Embryonic Lethal, Abnormal Vision, Drosophila-Like 1, Involves in Hepatitis C Replication2017
- Author(s)
  Kao YT, Goto K, Aoyagi H, Hossam GE, Zheng X, Puig-Basagoiti F, Watashi K, Suzuki R, Yamagoe S, Dohmae N, Suzuki T, Okushin K, Tsutsumi T, Yotsuyanagi H, Moriya K, Koike K, Suzuki T, Wakita T, Aizaki H
- Organizer
  24th International Symposium on Hepatitis C Virus and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] The bidirectional interplay of hepatitis B virus and cell-death inducing DFF45-like effectors2017
- Author(s)
  Kasai H, Yasumoto J, Yamashita A, Tanaka T, Watashi K, Wakita T, Otoguro T, Moriishi K
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] 胆汁酸代謝調節機構を標的としたB型肝炎ウイルス制御の試み2017
- Author(s)
  伊藤清顕、渡士幸一、米田政志
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Antiviral effect of bile acid derivatives on hepatitis B virus infection2017
- Author(s)
  Okumura A, Ito K, Watashi K, Takeuchi J, Inoue R, Suzuki S, Sakamoto K, Okutsu S, Umezawa K, Wakita T, Yoneda M
- Organizer
  2017 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Abnormal hepatocellular organelles remain to be observed in sustained virological response patients2017
- Author(s)
  Aoyagi H, Iijima H, Puig-Basagoiti F, Zheng X, Kao YT, Hossam GE, Matsuda M, Watashi K, Suzuki R, Masaki T, Aizawa N, Shimada N, Kato K, Tsubota A, Mimata A, Sakamaki Y, Ichinose S, Wake K, Wakita T, Aizaki H
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] The bidirectional interplay of hepatitis B virus and cell-death inducing DFF45-like effectors2017
- Author(s)
  Kasai H, Yasumoto J, Yamashita A, Tanaka T, Watashi K, Wakita T, Otoguro T, Moriishi K
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Targeting HBV-X by regulating Non-Stop mediated RNA decay2017
- Author(s)
  Aly HH, Shiromoto F, Kato T, Watashi K, Chayama K, Wakita T
- Organizer
  5th JAPAN-TAIWAN-KOREA HBV Research Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] HBV exploit Ski2/RNA complex to degrade cytokines and suppress inflammation2017
- Author(s)
  Aly HH, Shiromoto F, Watashi K, Kato T, Chayama K, Wakita T
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Crosstalk of Xenobiotic Metabolism Pathway with Lipid Metabolism regulates the Host Permissiveness to Hepatitis C Virus Production2017
- Author(s)
  Ohashi H, Nakajima S, Kim S, Suzuki R, Aizaki H, Fukasawa M, Kamisuki S, Sugawara F, Ohtani N, Wakita T, Watashi K
- Organizer
  第14回ウイルス学キャンプin湯河原
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Novel crosstalk of Xenobiotic Response with Lipid Biosynthesis Pathway regulates the Host Permissiveness to the Hepatitis C Virus Production2017
- Author(s)
  Ohashi H, Nakajima S, Kim S, Fukasawa M, Suzuki R, Aizaki H, Sugawara F, Ohtani N, Wakita T, Watashi K
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Analysis of HBV life cycle in the HepG2 expressing human NTCP cell line2017
- Author(s)
  Rahayu R, Ohsaki E, Honda T, Okamoto T, Watashi K, Ueda K
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-17H04085
[Presentation] Sphingomyelin is a component in the membranous replication factories2016
- Author(s)
  Gewaid HE, Aoyagi H, Watashi K, Suzuki R, Aly HH, Kumajai K, Yamaji T, Fukasawa M, Mimata A, Sakamaki Y, Ichinose S, Hanada K, Wakita T, Aizaki H
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  京都
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] B型肝炎ウイルスを標的とした新規侵入阻害剤の同定と作用機序の解析2016
- Author(s)
  九十田千子、渡士幸一、小嶋聡一、脇田隆字
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  幕張
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] ISG20 inhibits HBV replication by accelerating decay of HBV genome2016
- Author(s)
  Funami K, Leong CR, Oshiumi H, Okamoto M, Takaki H, Matsumoto M, Chayama K, Watashi K, Seya T
- Organizer
  The 64th Annual Meeting of the Japanese Society for Virology
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] DDX3 and INI1/hSNF5 restrict HBV replication through alteration of subcellular localization of HBx2016
- Author(s)
  Ariumi Y, Watashi K, Wakita T
- Organizer
  2016 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  ソウル
- Year and Date
  2016-09-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Human hepatic stellate cells are permissive for hepatitis C virus infection/replication and play important roles in fibrosis2016
- Author(s)
  Zaitsu T, Aoyagi H, Matsuda M, Watanabe N, Fujimoto A, Watashi K, Suzuki R, Fukuhara T, Matsuura M, Wake K, Suzuki T, Matsuura T, Tamura K, Wakita T, Aizaki H
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  京都
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 脂肪酸生合成経路の阻害によるHBV粒子の産生抑制機構の解析2016
- Author(s)
  岡村瞳、赤堀祐一、金ソルイ、渡士幸一、脇田隆字、土方誠
- Organizer
  第26回抗ウイルス療法学会総会
- Place of Presentation
  名古屋
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 肝炎ウイルスの創薬研究2016
- Author(s)
  渡士幸一
- Organizer
  京都大学ウイルス研究所セミナー, ウイルス研究の潮流シリーズ
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Establishment of the method for evaluating molecular interaction between hepatitis B virus entry inhibitors and sodium taurocholate cotransporting polypeptide2016
- Author(s)
  Fukano K, Shimura S, Peel M, Sluder A, Kawai F, Tsukuda S, Suzuki R, Aizaki H, Park SY, Wakita T, Ogasawara Y, Watashi K
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  京都
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Mechanism of HBV entry and the role of NTCP2016
- Author(s)
  Watashi K
- Organizer
  APASL Single Topic Conference (STC) - 6th HBV Conference
- Place of Presentation
  北京
- Year and Date
  2016-12-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 肝炎ウイルスの基礎研究から創薬研究へ2016
- Author(s)
  渡士幸一
- Organizer
  明治薬科大学セミナー
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Multiple flaviviruses neutralization assay based on single-round infectious particles2016
- Author(s)
  Matsuda M, Yamanaka A, Yoshii K, Watashi K, Aizaki H, Konishi E, Takasaki T, Wakita T, Suzuki R
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  京都
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Characterization of origomeric flavonoids as a novel class of anti-HBV entry inhibitors that directly target viral envelope protein2016
- Author(s)
  Tsukuda S, Watashi K, Hojima T, Isogawa M, Suzuki R, Aizaki H, Kojima S, Sugiyama M, Saito A, Tanaka Y, Mizokami M, Wakita T
- Organizer
  The 64th Annual Meeting of the Japanese Society for Virology
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Activation of protein kinase R by hepatitis C virus RNA-dependent RNA polymerase2016
- Author(s)
  Suzuki R, Matsuda M, Shimoike T, Watashi K, Aizaki H, Kato T, Suzuki T, Wakita T
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  京都
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] B型肝炎ウイルス侵入過程を標的とした創薬研究2016
- Author(s)
  渡士幸一、九十田千子、脇田隆字
- Organizer
  第41回日本肝臓学会東部会
- Place of Presentation
  東京
- Year and Date
  2016-12-08
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 細胞培養系を用いた新規抗B型肝炎ウイルス化合物の同定2016
- Author(s)
  Kaneko M, Watashi K, Iwamoto M, Kamisuki S, Matsunaga H, Iwamoto M, Kawai F, Ohashi H, Tsukuda S, Shimura S, Suzuki R, Aizaki H, Sugiyama M, Park SY, Ito T, Ohtani N, Sugawara F, Tanaka Y, Mizokami M, Sureau C, Wakita T
- Organizer
  第13回ウイルス学キャンプ in 湯河原
- Place of Presentation
  湯河原
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Development of a neutralization assay for multiple flaviviruses based on single-round infectious particles2016
- Author(s)
  Matsuda M, Yamanaka A, Yoshii K, Watashi K, Aizaki H, Konishi E, Takasaki T, Wakita T, Suzuki R
- Organizer
  The 64th Annual Meeting of the Japanese Society for Virology
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] ピリミドトリアジノン誘導体の抗HBV効果について2016
- Author(s)
  外山政明、濱崎隆之、岡本実佳、渡士幸一、脇田隆字、馬場昌範
- Organizer
  第26回抗ウイルス療法学会総会
- Place of Presentation
  名古屋
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] B型肝炎ウイルスの適応進化メカニズム解析2016
- Author(s)
  竹内（柴田）潤子、岩本将士、渡士幸一
- Organizer
  第13回ウイルス学キャンプ in 湯河原
- Place of Presentation
  湯河原
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 新規作用機序を有するB型肝炎ウイルス創薬2016
- Author(s)
  渡士幸一、九十田千子、脇田隆字
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  幕張
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Precore stop codon regulates the stability of HBV X-mRNA2016
- Author(s)
  Aly HH, Suzuki J, Watashi K, Chayama K, Wakita T
- Organizer
  4th Taiwan-Korea-Japan Research Symposium on Hepatitis B Virus
- Place of Presentation
  台北
- Year and Date
  2016-04-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Development of novel hepatitis B virus culture system using immortalized human hepatocytes2016
- Author(s)
  Akahori Y, Kato H, Fujita T, Moriishi K, Watashi K, Wakita T, Hijikata M
- Organizer
  The 64th Annual Meeting of the Japanese Society for Virology
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Development of Novel Anti-viral Agents against Hepatitis B Virus by using an siRNA Screening Panel Targeting the Carbohydrate Synthesis System2016
- Author(s)
  Ito K, Yoneda M, Angata K, Watashi K, Wakita T, Tanaka Y, Mizokami M, Narimatsu H
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  京都
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Proanthocyanidin and its analogs are new class of HBV and HDV entry inhibitors that target the viral preS1 region2016
- Author(s)
  Tsukuda S, Watashi K, Hojima T, Isogawa M, Iwamoto M, Suzuki R, Aizaki H, Kojima S, Sugiyama M, Saito A, Tanaka Y, Mizokami M, Wakita T
- Organizer
  2016 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  ソウル
- Year and Date
  2016-09-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Strategy for hepatitis B and D virus entry inhibition without impairing NTCP-mediated bile acid uptake2016
- Author(s)
  Watashi K, Shimura S, Peel M, Sluder A, Kawai F, Iwamoto M, Tsukuda S, Suzuki R, Aizaki H, Sugiyama M, Park SY, Tanaka Y, Mizokami M, Wakita T
- Organizer
  The 64th Annual Meeting of the Japanese Society for Virology
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Role of lipid droplets in the emergence of drug resistant virus against direct acting antivirals2016
- Author(s)
  Ohashi H, Nakajima S, Kim S, Suzuki R, Aizaki H, Fukasawa F, Kamisuki S, Sugawara F, Ohtani N, Wakita T, Watashi K
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  京都
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Hepatitis B virus capsid formation is regulated by microtubules and their posttranslational modification2016
- Author(s)
  Iwamoto M, Sugiyama M, Suzuki R, Aizaki H, Tanaka Y, Mizokami M, Ohtani N, Wakita T, Watashi K
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  京都
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 低分子化合物を用いたB型肝炎ウイルスの感染感受性決定機構の解析2016
- Author(s)
  Tsukuda S, Watashi K, Iwamoto M, Suzuki R, Aizaki H, Kojima S, Wakita T
- Organizer
  第13回ウイルス学キャンプ in 湯河原
- Place of Presentation
  湯河原
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Aryl hydrocarbon receptor regulates the assembly of hepatitis C virus and affects the emergence of drug resistant virus against DAAs2016
- Author(s)
  Ohashi H, Syo Nakajima, Sulyi Kim, Suzuki R, Aizaki H, Fukasawa M, Kamisuki S, Sugawara F, Ohtani N, Wakita T, Watashi K
- Organizer
  The 64th Annual Meeting of the Japanese Society for Virology
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 立体培養したHBV受容体hNTCP発現不死化ヒト肝細胞による新たなHBV培養系を用いた抗HBV薬評価系の構築2016
- Author(s)
  赤堀祐一、加藤博己、藤田尚志、森石恆司、渡士幸一、脇田隆字、土方誠
- Organizer
  第26回抗ウイルス療法学会総会
- Place of Presentation
  名古屋
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Development of Novel Anti-viral Agents against Hepatitis B Virus by using an siRNA Screening Panel Targeting the Carbohydrate Synthesis2016
- Author(s)
  Ito K, Yoneda M, Angata K, Watashi K, Wakita T, Tanaka Y, Tong S, Mizokami M, Narimatsu H
- Organizer
  2016 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  ソウル
- Year and Date
  2016-09-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] A novel tricyclic polyketide, vanitaracin A, specifically inhibits the entry of hepatitis B and D viruses through targeting NTCP2016
- Author(s)
  Kaneko M, Watashi K, Kamisuki S, Matsunaga H, Iwamoto M, Kawai F, Ohashi H, Tsukuda S, Shimura S, Suzuki R, Aizaki H, Sugiyama M, Sam-Yong Park, Ito T, Ohtani N, Sugawara F, Tanaka Y, Mizokami M, Sureau C, Wakita T
- Organizer
  東京理科大学イメージングフロンティアセンターシンポジウム
- Place of Presentation
  野田
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Non-Stop mediated RNA decay mechanism targets HBV-X mRNA for degradation at the RNA exosome2016
- Author(s)
  Aly H, Watashi K, Chayama K, Hijikata M, Wakita T
- Organizer
  The 64th Annual Meeting of the Japanese Society for Virology
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] The HCV cell culture system identified fungal-derived neoechinulin B as a novel antagonist of liver X receptor2016
- Author(s)
  Watashi K, Nakajima S, Ohashi H, Kamisuki S, Kwon ATJ, Suzuki H, Tsukuda S, Suzuki R, Aizaki H, Kato T, Sugawara F, Wakita T
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  京都
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Aryl hydrocarbon receptorのC型肝炎ウイルス感染応答における役割・分子メカニズムの解析2016
- Author(s)
  Ohashi H, Nakajima S, Kim S, Suzuki R, Aizaki H, Fukasawa M, Kamisuki S, Sugawara F, Ohtani N, WakitaT, Watashi K
- Organizer
  第13回ウイルス学キャンプ in 湯河原
- Place of Presentation
  湯河原
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Protein kinase C triggers the internalization of hepatitis B and D viruses into hepatocytes2016
- Author(s)
  Iwamoto M, Kaneko M, Ohashi H, Kawai F, Suzuki R, Aizaki H, Park SY, Ryo A, Ohtani N, Wakita T, Watashi K
- Organizer
  The 64th Annual Meeting of the Japanese Society for Virology
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Inhibition of HBV entry process through targeting host and viral molecules2016
- Author(s)
  Tsukuda S, Watashi K, Hamada Y, Isogawa M, Iwamoto M, Suzuki R, Aizaki H, Kojima S, Sugiyama M, Saito A, Tanaka Y, Mizokami M, Wakita T
- Organizer
  4th Taiwan-Korea-Japan Research Symposium on Hepatitis B Virus
- Place of Presentation
  台北
- Year and Date
  2016-04-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Induction of NTCP expression in a human HCC cell line by retinoic acid and its possible effect on host susceptibility to HBV infection2016
- Author(s)
  Masaki T, Matsumoto Y, Aizaki H, Nagamori shushi, Watashi K, Park J, Kanai Y, Kojima S, Wakita T, Matsuura T
- Organizer
  2016 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  ソウル
- Year and Date
  2016-09-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 肝炎ウイルス研究の現状と、抗ウイルス創薬研究2016
- Author(s)
  渡士幸一
- Organizer
  Summer Retrovirus Conference (SRC) 2016
- Place of Presentation
  京都
- Year and Date
  2016-07-07
- Invited
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] B型肝炎ウイルスの侵入受容体阻害剤の同定とその機序の解析2016
- Author(s)
  Fukano K, Shimura S, Peel M, Sluder A, Kawai F, Tsukuda S, Suzuki R, Aizaki H, Park SY, Wakita T, Ogasawara Y, Watashi K
- Organizer
  第13回ウイルス学キャンプ in 湯河原
- Place of Presentation
  湯河原
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Non-Stop mediated RNA decay mechanism regulates Hepatitis B virus replication2016
- Author(s)
  Aly HH, Watashi K, Chayama K, Wakita T
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  京都
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] B型肝炎ウイルス粒子を直接標的とする侵入阻害剤proanthocyanidin2016
- Author(s)
  九十田千子、渡士幸一、濱田義知、齊藤安貴子、五十川正記、田中義正、鈴木亮介、相崎英樹、小嶋聡一、杉山真也、田中靖人、溝上雅史、脇田隆字
- Organizer
  第26回抗ウイルス療法学会総会
- Place of Presentation
  名古屋
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Non-Stop mediated RNA quality control decay regulates HBV X-mRNA2016
- Author(s)
  Aly HH, Suzuki J, Watashi K, Hijikata M, Kato T, Chayama K, Wakita T
- Organizer
  2016 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  ソウル
- Year and Date
  2016-09-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Vanitaracin A is a novel entry inhibitor of hepatitis B and D viruses through targeting NTCP2016
- Author(s)
  Kaneko M, Watashi K, Kamisuki S, Iwamoto M, Tsukuda S, Ohashi H, Kawai F, Mizokami M, Park SY, Tanaka Y, Suzuki R, Aizaki H, Sugawara F, Otani N, Wakita T
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  京都
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Fatty acid biosynthesis specifically regulates hepatitis B virus particle production2016
- Author(s)
  Okamura H, Akahori Y, Nio Y, Watashi K, Wakita T, Hijikata M
- Organizer
  The 64th Annual Meeting of the Japanese Society for Virology
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Retinoid inhibitors abolish the host permissiveness to hepatitis B virus infection by modulating the expression of NTCP2016
- Author(s)
  Tsukuda S, Watashi K, Iwamoto M, Suzuki R, Aizaki H, Kojima S, Sugiyama M, Tanaka Y, Mizokami M, Wakita T
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  京都
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] B型肝炎ウイルス感染を阻害する新規macrocyclesの同定と、NTCP依存性胆汁酸取り込み抑制能を欠失した選択的阻害剤の創出2016
- Author(s)
  渡士幸一、志村聡美、Michael Peel、Ann Sluder、河合文啓、岩本将士、杉山真也、朴三用、田中靖人、溝上雅史、脇田隆字
- Organizer
  第26回抗ウイルス療法学会総会
- Place of Presentation
  名古屋
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter, sodium taurocholate cotransporting polypeptide (NTCP)2016
- Author(s)
  渡士幸一
- Organizer
  第29回肝臓フォーラム（東部）
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Strategy for hepatitis B and D virus entry inhibition without affecting bile acid transport2016
- Author(s)
  Watashi K, Shimura S, Peel M, Sluder A, Kawai F, Iwamoto M, Tsukuda S, Suzuki R, Aizaki H, Sugiyama M, Park SY, Tanaka Y, Mizokami M, Wakita T
- Organizer
  2016 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  ソウル
- Year and Date
  2016-09-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Analysis of the HBV life cycle in a HepG2 expressing human NTCP2016
- Author(s)
  Rahayu R, Ohsaki E, Okamoto T, Watashi K, Ueda K
- Organizer
  The 64th Annual Meeting of the Japanese Society for Virology
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] The cell line derived from immortalized human hepatocytes was highly susceptible to blood-borne hepatitis B virus in the three-dimensional culture condition2016
- Author(s)
  Akahori Y, Kato H, Fujita T, Moriishi K, Watashi K, Wakita T, Hijikata M
- Organizer
  2016 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  ソウル
- Year and Date
  2016-09-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] HCVに対する抗ウイルス治療後、SVR後の肝細胞の超微細構造の変化2016
- Author(s)
  青柳東代、飯島尋子、松田麻未、渡士幸一、鈴木亮介、政木隆博、坂巻有里子、市野瀬志津子、坪田昭人、和氣健二郎、脇田隆字、相崎英樹
- Organizer
  第26回抗ウイルス療法学会総会
- Place of Presentation
  名古屋
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] A novel Neplanocin A derivatives selectively inhibit HBV replication2016
- Author(s)
  Toyama M, Hamasaki T, Okamoto M, Ikeda M, Watashi K, Wakita T, Yamashita A, Moriishi K, Sharon A, Baba M
- Organizer
  2016 International HBV Meeting The Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  ソウル
- Year and Date
  2016-09-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Protein kinase C triggers the internalization of hepatitis B and D viruses into hepatocytes2016
- Author(s)
  Iwamoto M, Kaneko M, Ohashi H, Kawai F, Suzuki R, Aizaki H, Park SY, Ryo A, Ohtani N, Wakita T, Watashi K
- Organizer
  第13回ウイルス学キャンプ in 湯河原
- Place of Presentation
  湯河原
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Neoechinulin Bのliver X receptor転写阻害効果の同定およびそれによるC型肝炎ウイルス複製制御機構の解析2015
- Author(s)
  渡士幸一, 中嶋翔, 紙透伸治, Izaguirre-Carbonell J, Kwon Atj, 鈴木治和, 九十田千子, 岡田麻衣子, 鈴木亮介, 相崎英樹, 菅原二三男, 脇田隆字
- Organizer
  第25回抗ウイルス療法学会総会
- Place of Presentation
  東京
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] SKIV2L-mediated RNA-exosome regulation of HBV replication2015
- Author(s)
  Aly HH, Watashi K, Chayama K, Kato T, Wakita T
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] B型肝炎ウイルスに対する直接標的薬proanthocyanidinおよび宿主標的薬vanitaracinの同定および感染阻害機構の解析2015
- Author(s)
  渡士幸一, 九十田千子, 金子学, 松永大輝, 紙透伸治, 齊藤安貴子, 鈴木亮介, 相崎英樹, 杉山真也, 溝上雅史, 菅原二三男, 田中靖人, 脇田隆字
- Organizer
  第25回抗ウイルス療法学会総会
- Place of Presentation
  東京
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] ウイルス感染増殖系を基盤とした天然化合物の新規生理機能の解析2015
- Author(s)
  渡士幸一
- Organizer
  天然物ケミカルバイオロジー分子標的と活性制御第7回公開シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2015-06-08
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Egression of hepatitis B virus particles is promoted by long chain saturated fatty acid2015
- Author(s)
  Okamura H, Akahori Y, Kim S, Nio Y, Watashi K, Wakita T, Hijikata M
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Quantifying activity optimizes drug combinations against hepatitis C virus infection2015
- Author(s)
  Iwami S, Tanaka Y, Wakita T, Watashi K
- Organizer
  22nd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Strasbourg (France)
- Year and Date
  2015-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Molecular dissection of HBV evasion from restriction factor tetherin2015
- Author(s)
  Miyakawa K, Matsunaga S, Watashi K, Sugiyama M, Mizokami M, Wakita T, Ryo A
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Surfeit 4 is involved in HCV replication by interacting with NS4B2015
- Author(s)
  Kong L, Aoyagi H, Matsuda M, Fujimoto A, Watashi K, Suzuki R, Yamagoe S, Dohmae N, Suzuki T, Sakamaki Y, Ichinose S, Suzuki T, Wakita T, Aizaki H
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Development of anti-HBs monoclonal antibody targeting HBs-NTCP interaction2015
- Author(s)
  Matsunaga S, Miyakawa K, Watashi K, Sugiyama M, Mizokami M, Wakita T, Ryo A
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Development of anti-HBs monoclonal antibody targeting HBs-NTCP interaction2015
- Author(s)
  Matsunaga S, Miyakawa K, Watashi K, Sugiyama M, Mizokami M, Wakita T, Ryo A
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Japanese encephalitis virus (JEV)-subviral particles harboring HCV neutralization epitopes elicit neutralizing antibodies against JEV and HCV2015
- Author(s)
  Saga R, Fujimoto A, Watanabe N, Matsuda M, Hasegawa M, Watashi K, Aizaki H, Nakamura N, Konishi E, Kato T, Takeyama H, Wakita T, Suzuki R
- Organizer
  22nd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Strasbourg (France)
- Year and Date
  2015-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Cilnidipine inhibits the early phase of HBV infection in a NTCP-independent mechanism2015
- Author(s)
  Tsukuda S, Watashi K, Iwamoto M, Suzuki R, Aizaki H, Kojima S, Tanaka Y, Wakita T
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] C型肝炎治療薬の個性を探る～多剤併用から費用対効果の考察まで～2015
- Author(s)
  渡士幸一
- Organizer
  ウイルス感染現象における宿主細胞コンピテンシーの分子基盤第2回若手研究会
- Place of Presentation
  三浦
- Year and Date
  2015-07-18
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Identification of novel pyrimidotriazinone derivatives as inhibitors of HBV replication2015
- Author(s)
  Toyama M, Hamasaki T, Okamoto M, Watashi K, Wakita T, Baba M
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Development ofa cell culture and infection system for hepatitis B virus using 3D cultured non-neoplasmic HuS-E/2 cells2015
- Author(s)
  Akahori Y, Kato H, Fujita T, Moriishi K, Watashi K, Wakita T, Hijikata M
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Bivalent vaccine platform based on Japanese encephalitis virus (JEV) elicit neutralizing antibodies against JEV and hepatitis C virus2015
- Author(s)
  Saga R, Fujimoto A, Watanabe N, Matsuda M, Hasegawa M, Watashi K, Aizaki H, Nakamura N, Konishi E, Kato T, Tajima S, Takasaki T, Takeyama H, Wakita T, Suzuki R
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] AAV-delivered engineered repressor transcription activator-like effectors (rTALEs) inactivate hepatitis B virus replication in hNTCP cells and in mice2015
- Author(s)
  Moyo B, Nicholson S, Roelofse I, Bloom K, Mussolino C, Cathomen T, Watashi K, Ely A, Arbuthnot P
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Investigation of the mechanism of interaction between host glycosylation system and hepatitis B virus replication system2015
- Author(s)
  Ito K, Yoneda M, Angata K, Watashi K, Wakita T, Iijima S, Tanaka Y, Tong S, Kuno A, Sugiyama M, Mizokami M, Narimatsu H
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Dual function of RIG-I as innate antiviral mediator against hepatitis B virus2015
- Author(s)
  Sato S, Li K, Kameyama T, Hayashi T, Ishida Y, Murakami S, Watanabe T, Iijima S, Sakurai Y, Watashi K, Tsutsumi S, Sato Y, Akita H, Wakita T, Rice Cm, Harashima H, Kohara M, Tanaka Y, Takaoka A
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Identification of flavonoid derivative that directly acts on hepatitis B virus surface protein and inhibits viral entry2015
- Author(s)
  Tsukuda S, Watashi K, Hamada Y, Isogawa M, Iwamoto M, Suzuki R, Aizaki H, Kojima S, Sugiyama M, Saito A, Tanaka Y, Mizokami M, Wakita T
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Metachromin A, sesquiterpene from marine sponge Dactylospongia metachromia, exerts anti-HBV activity via inhibition of HBV core promoter2015
- Author(s)
  Yamashita A, Tanaka T, Okuyama-Dobashi K, Kasai H, Watashi K, Wakita T, Toyama M, Baba M, Moriishi K
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Development of a cell culture and infection system for hepatitis B virus using 3D cultured immortalized human hepatocytes2015
- Author(s)
  Akahori Y, Kato H, Fujita T, Moriishi K, Watashi K, Wakita T, Hijikata M
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] NTCPを標的としたB型肝炎ウイルス感染阻害戦略2015
- Author(s)
  渡士幸一
- Organizer
  第31回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-07-02
- Invited
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Identification of NTCP-targeting small molecules that inhibit HBV entry by cell-based and in vitro technologies2015
- Author(s)
  Watashi K, Tsukuda S, Shimura S, Kaneko M, Sluder A, Peel M, Kamisuki S, Matsunaga S, Morishita R, Futamura Y, Kondoh Y, Suzuki R, Aizaki H, Sugiyama M, Borroto-Esoda K, Ryo A, Sugawara F, Osada H, Tanaka Y, Mizokami M, Wakita T
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Hepatitis B virus downregulates expression of CIDE-B and CIDE-C and impairs lipid droplet growth2015
- Author(s)
  Yasumoto J, Kasai H, Tanaka T, Watashi K, Wakita T, Yamashita A, Dobashi-Okuyama K, Moriishi K
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Egression of hepatitis B virus particles is promoted by long chain saturated fatty acid2015
- Author(s)
  Okamura H, Akahori Y, Kim S, Nio Y, Watashi K, Wakita T, Hijikata M
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Identification of a new tricyclic polyketide, vanitaracin A, which inhibits the entry of HBV, HDV, and nucleoside analog-resistant HBV though targeting NTCP2015
- Author(s)
  Kaneko M, Watashi K, Kamisuki S, Matsunaga H, Iwamoto M, Kawai F, Ohashi H, Tsukuda S, Shimura S, Suzuki R, Aizaki H, Sugiyama M, Park SY, Ohtani N, Sugawara F, Tanaka Y, Mizokami M, Sureau C, Wakita T
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Long chain saturated fatty acid contributes to efficient egression of hepatitis B virus particles2015
- Author(s)
  Okamura H, Akahori Y, Kim S, Nio Y, Watashi K, Wakita T, Hijikata M
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] NTCP as a drug target of anti-hepatitis B virus infection2015
- Author(s)
  Watashi K
- Organizer
  2015 American Association of Pharmaceutical Scientists (AAPS)/ International Transporter Consortium (ITC) Workshop on Drug Transporter in ADME: From the Bench to the Bedside
- Place of Presentation
  Baltimore (USA)
- Year and Date
  2015-04-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Multimerization of hepatitis B virus core protein regulated by microtubules2015
- Author(s)
  Iwamoto M, Watashi K, Sugiyama M, Suzuki R, Aizaki H, Tanaka Y, Mizokami M, Ohtani N, Koiwai O, Wakita T
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] ウイルス感染増殖系を基盤とした天然化合物の新規生理機能の解析2015
- Author(s)
  渡士幸一
- Organizer
  天然物ケミカルバイオロジー分子標的と活性制御第7回公開シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2015-06-08
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Flutamide-mediated disruption of lipid droplets impairs the host permisiveness to hepatitis C virus production2015
- Author(s)
  Ohashi H, Watashi K, Nakajima S, Kim S, Suzuki R, Aizaki H, Fukasawa M, Kamisuki S, Sugawara F, Ohtani N, Wakita T
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 海綿由来セキステルペン系化合物metachromin AのB型肝炎ウイルスコアプロモーター抑制活性を介した抗ウイルス活性2015
- Author(s)
  山下篤哉, 田中智久, 土橋香織, 葛西宏威, 渡士幸一, 脇田隆字, 外山正明, 馬場昌範, 前川伸哉, 榎本信幸, 玉城麻友美, 田中淳一, 森石恆司
- Organizer
  BMB 2015
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] 新規核酸誘導体7-deazaneplanocin A誘導体の抗HBV効果について2015
- Author(s)
  外山政明, 濱崎隆之, 岡本実佳, 渡士幸一, 脇田隆字, Ashoke Sharon, 馬場昌範
- Organizer
  第25回抗ウイルス療法学会総会
- Place of Presentation
  東京
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Flutamide-mediated disruption of lipid droplets impairs the host permisiveness to hepatitis C virus production2015
- Author(s)
  Ohashi H, Watashi K, Nakajima S, Kim S, Suzuki R, Aizaki H, Fukasawa M, Kamisuki S, Sugawara F, Ohtani N, Wakita T
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] A new fungi-derived vanitaracin A specifically inhibits the entry of hepatitis B and D viruses through interacting with NTCP2015
- Author(s)
  Kaneko M, Watashi K, Kamisuki S, Matsunaga H, Iwamoto M, Kawai F, Ohashi H, Tsukuda S, Shimura S, Suzuki R, Aizaki H, Sugiyama M, Park Sy, Ohtani N, Sugawara F, Tanaka Y, Mizokami M, Wakita T
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] NTCP as a drug target of anti-hepatitis B virus infection2015
- Author(s)
  Watashi K
- Organizer
  2015 American Association of Pharmaceutical Scientists (AAPS)/ International Transporter Consortium (ITC) Workshop on Drug Transporter in ADME: From the Bench to the Bedside
- Place of Presentation
  Baltimore (USA)
- Year and Date
  2015-04-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 創薬を指向した肝炎ウイルス感染増殖機構の解析2015
- Author(s)
  渡士幸一
- Organizer
  京都大学ウイルス研究所　ウイルス研究の潮流
- Place of Presentation
  京都
- Year and Date
  2015-07-15
- Invited
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 新規真菌二次代謝産物 SF177 の B 型肝炎ウイルス感染阻害活性および NTCP トランスポーター阻害活性の同定2015
- Author(s)
  金子学, 渡士幸一, 松永大輝, 紙透伸治, 岩本将士, 河合文啓, 鈴木亮介, 相崎英樹, 朴三用, 菅原二三男, 脇田隆字
- Organizer
  第25回抗ウイルス療法学会総会
- Place of Presentation
  東京
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] SKIV2L-dependent HBV-RNA degradation by the RNA-exosome, a new anti-HBV host mechanism2015
- Author(s)
  Aly HH, Watashi K, Chayama K, Kato T, Wakita T
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Development ofa cell culture and infection system for hepatitis B virus using 3D cultured non-neoplasmic HuS-E/2 cells2015
- Author(s)
  Akahori Y, Kato H, Fujita T, Moriishi K, Watashi K, Wakita T, Hijikata M
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Chemical genetics for virus research: Interface of drug development and basic virology2015
- Author(s)
  Watashi K
- Organizer
  The 63rd Annual Meeting of the Japanese Society for Virology
- Place of Presentation
  福岡
- Year and Date
  2015-11-22
- Invited
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Hepatitis C virus cell culture system identifies fungi-derived NeoB as a liver X receptor inhibitor2015
- Author(s)
  Watashi K
- Organizer
  Pacifichem 2015
- Place of Presentation
  Honolulu
- Year and Date
  2015-12-16
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Anti-HBV talens delivered by recombinant adeno-associated viral vectors (rAAV) efficiently inhibit HBV replication in vivo and in vitro2015
- Author(s)
  Nicholson S, Moyo B, Bloom K, Mussolino C, Cathomen T, Watashi K, Ely A, Arbuthnot P
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Anti-HBV talens delivered by recombinant adeno-associated viral vectors (rAAV) efficiently inhibit HBV replication in vivo and in vitro2015
- Author(s)
  Nicholson S, Moyo B, Bloom K, Mussolino C, Cathomen T, Watashi K, Ely A, Arbuthnot P
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Neoechinulin Bのliver X receptor転写阻害効果の同定およびそれによるC型肝炎ウイルス複製制御機構の解析2015
- Author(s)
  渡士幸一, 中嶋翔, 紙透伸治, Izaguirre-Carbonell J, Kwon Atj, 鈴木治和, 九十田千子, 岡田麻衣子, 鈴木亮介, 相崎英樹, 菅原二三男, 脇田隆字
- Organizer
  第25回抗ウイルス療法学会総会
- Place of Presentation
  東京
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] AAV-delivered engineered repressor transcription activator-like effectors (rTALEs) inactivate hepatitis B virus replication in hNTCP cells and in mice2015
- Author(s)
  Moyo B, Nicholson S, Roelofse I, Bloom K, Mussolino C, Cathomen T, Watashi K, Ely A, Arbuthnot P
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Identification of novel pyrimidotriazinone derivatives as inhibitors of HBV replication2015
- Author(s)
  Toyama M, Hamasaki T, Okamoto M, Watashi K, Wakita T, Baba M
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] B型肝炎ウイルスに対する直接標的薬proanthocyanidinおよび宿主標的薬vanitaracinの同定および感染阻害機構の解析2015
- Author(s)
  渡士幸一, 九十田千子, 金子学, 松永大輝, 紙透伸治, 齊藤安貴子, 鈴木亮介, 相崎英樹, 杉山真也, 溝上雅史, 菅原二三男, 田中靖人, 脇田隆字
- Organizer
  第25回抗ウイルス療法学会総会
- Place of Presentation
  東京
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 新規核酸誘導体7-deazaneplanocin A誘導体の抗HBV効果について2015
- Author(s)
  外山政明, 濱崎隆之, 岡本実佳, 渡士幸一, 脇田隆字, Ashoke Sharon, 馬場昌範
- Organizer
  第25回抗ウイルス療法学会総会
- Place of Presentation
  東京
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] ヒト肝癌細胞 FLC4 における B 型肝炎ウイルスレセプター NTCP の発現と誘導に関する検討2015
- Author(s)
  松浦知和, 松本喜弘, 永森収志, 渡士幸一, 金井好克, 小嶋聡一, 脇田隆字, 相崎英樹
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  熊本
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Investigation of mechanisms of interaction between host glycosylation system and hepatitis B virus replication system2015
- Author(s)
  Okutsu S, Ito K, Yoneda M, Angata K, Watashi K, Wakita T, Iijima S, Tanaka Y, Tong S, Mizokami M, Narimatsu H
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Development of a cell culture and infection system for hepatitis B virus using 3D cultured immortalized human hepatocytes2015
- Author(s)
  Akahori Y, Kato H, Fujita T, Moriishi K, Watashi K, Wakita T, Hijikata M
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Transfer hepatitis C virus from human liver cells to hepatic stellate cells2015
- Author(s)
  Zaitsu T, Aoyagi H, Fujimoto A, Matsuda M, Watanabe N, Watashi K, Suzuki R, Fukuhara T, Matsuura Y, Sakamaki Y, Ichinose S, Wake K, Suzuki T, Iijima H, Matsuura T, Tamura K, Wakita T, Aizaki H
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 新規真菌二次代謝産物 SF177 の B 型肝炎ウイルス感染阻害活性および NTCP トランスポーター阻害活性の同定2015
- Author(s)
  金子学, 渡士幸一, 松永大輝, 紙透伸治, 岩本将士, 河合文啓, 鈴木亮介, 相崎英樹, 朴三用, 菅原二三男, 脇田隆字
- Organizer
  第25回抗ウイルス療法学会総会
- Place of Presentation
  東京
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] ヒト肝癌細胞 FLC4 における B 型肝炎ウイルスレセプター NTCP の発現と誘導に関する検討2015
- Author(s)
  松浦知和, 松本喜弘, 永森収志, 渡士幸一, 金井好克, 小嶋聡一, 脇田隆字, 相崎英樹
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  熊本
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Identification of NTCP-targeting small molecules that inhibit HBV entry by cell-based and in vitro technologies2015
- Author(s)
  Watashi K, Tsukuda S, Shimura S, Kaneko M, Sluder A, Peel M, Kamisuki S, Matsunaga S, Morishita R, Futamura Y, Kondoh Y, Suzuki R, Aizaki H, Sugiyama M, Borroto-Esoda K, Ryo A, Sugawara F, Osada H, Tanaka Y, Mizokami M, Wakita T
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Hepatitis C virus cell culture system identifies fungi-derived NeoB as a liver X receptor inhibitor2015
- Author(s)
  Watashi K
- Organizer
  Pacifichem 2015
- Place of Presentation
  Honolulu
- Year and Date
  2015-12-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Inhibition of hepatitis B virus infection by docosahexaenoic acid in cultured cells2015
- Author(s)
  Fukasawa M, Shimizu Y, Shirasago Y, Watashi K, Tanaka Y, Wakita T, Kondoh M, Yagi K, Hanada K
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Japanese encephalitis virus (JEV)-subviral particles harboring HCV neutralization epitopes elicit neutralizing antibodies against JEV and HCV2015
- Author(s)
  Saga R, Fujimoto A, Watanabe N, Matsuda M, Hasegawa M, Watashi K, Aizaki H, Nakamura N, Konishi E, Kato T, Takeyama H, Wakita T, Suzuki R
- Organizer
  22nd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Strasbourg (France)
- Year and Date
  2015-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Hepatitis B virus downregulates expression of CIDE-B and CIDE-C and impairs lipid droplet growth2015
- Author(s)
  Yasumoto J, Kasai H, Tanaka T, Watashi K, Wakita T, Yamashita A, Dobashi-Okuyama K, Moriishi K
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] B型肝炎ウイルスの感染に対するRIG-Iを介した自然免疫応答機構2015
- Author(s)
  佐藤精一, 李凱, 亀山武志, 林隆也, 石田雄二, 村上周子, 渡邊綱正, 飯島沙幸, 櫻井遊, 渡士幸一, 堤進, 佐藤悠介, 秋田英万, 脇田隆字, Rice Cm, 原島秀吉, 小原道法, 田中靖人, 高岡晃教
- Organizer
  第25回抗ウイルス療法学会総会
- Place of Presentation
  東京
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Human iPS-derived hepatocytes as an in vitro HBV infection model2015
- Author(s)
  Sakurai F, Yamamoto T, Mitani S, Takayama K, Tachibana M, Watashi K, Wakita T, Iijima S, Tanaka Y, Mizuguchi H
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Pyrimidotriazinone derivatives as novel inhibitors of hepatitis B virus core assembly2015
- Author(s)
  Toyama M, Hamasaki T, Okamoto M, Watashi K, Wakita T, Baba M
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Dual function of RIG-I as innate antiviral mediator against hepatitis B virus2015
- Author(s)
  Sato S, Li K, Kameyama T, Hayashi T, Ishida Y, Murakami S, Watanabe T, Iijima S, Sakurai Y, Watashi K, Tsutsumi S, Sato Y, Akita H, Wakita T, Rice Cm, Harashima H, Kohara M, Tanaka Y, Takaoka A
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Multimerization of hepatitis B virus core protein regulated by microtubules2015
- Author(s)
  Iwamoto M, Watashi K, Sugiyama M, Suzuki R, Aizaki H, Tanaka Y, Mizokami M, Ohtani N, Koiwai O, Wakita T
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Cilnidipine inhibits the early phase of HBV infection in a NTCP-independent mechanism2015
- Author(s)
  Tsukuda S, Watashi K, Iwamoto M, Suzuki R, Aizaki H, Kojima S, Tanaka Y, Wakita T
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] カイメン由来化合物metachromin A及びその類縁化合物の抗HBV活性の検討2015
- Author(s)
  山下篤哉, 田中智久, 葛西宏威, 渡士幸一, 脇田隆字, 外山政明, 馬場昌範, 前川伸哉, 榎本信幸, 玉城麻友美, 田中淳一, 森石恆司
- Organizer
  第25回抗ウイルス療法学会総会
- Place of Presentation
  東京
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 海綿由来セキステルペン系化合物metachromin AのB型肝炎ウイルスコアプロモーター抑制活性を介した抗ウイルス活性2015
- Author(s)
  山下篤哉, 田中智久, 土橋香織, 葛西宏威, 渡士幸一, 脇田隆字, 外山正明, 馬場昌範, 前川伸哉, 榎本信幸, 玉城麻友美, 田中淳一, 森石恆司
- Organizer
  BMB 2015
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Investigation of mechanisms of interaction between host glycosylation system and hepatitis B virus replication system2015
- Author(s)
  Okutsu S, Ito K, Yoneda M, Angata K, Watashi K, Wakita T, Iijima S, Tanaka Y, Tong S, Mizokami M, Narimatsu H
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 創薬を指向した肝炎ウイルス感染増殖機構の解析2015
- Author(s)
  渡士幸一
- Organizer
  京都大学ウイルス研究所　ウイルス研究の潮流
- Place of Presentation
  京都
- Year and Date
  2015-07-15
- Invited
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Inhibition of hepatitis B virus infection by docosahexaenoic acid in cultured cells2015
- Author(s)
  Fukasawa M, Shimizu Y, Shirasago Y, Watashi K, Tanaka Y, Wakita T, Kondoh M, Yagi K, Hanada K
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Pyrimidotriazinone derivatives as novel inhibitors of hepatitis B virus core assembly2015
- Author(s)
  Toyama M, Hamasaki T, Okamoto M, Watashi K, Wakita T, Baba M
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] SKIV2L-mediated RNA-exosome regulation of HBV replication2015
- Author(s)
  Aly HH, Watashi K, Chayama K, Kato T, Wakita T
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Bivalent vaccine platform based on Japanese encephalitis virus (JEV) elicit neutralizing antibodies against JEV and hepatitis C virus2015
- Author(s)
  Saga R, Fujimoto A, Watanabe N, Matsuda M, Hasegawa M, Watashi K, Aizaki H, Nakamura N, Konishi E, Kato T, Tajima S, Takasaki T, Takeyama H, Wakita T, Suzuki R
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Human iPS-derived hepatocytes as an in vitro HBV infection model2015
- Author(s)
  Sakurai F, Yamamoto T, Mitani S, Takayama K, Tachibana M, Watashi K, Wakita T, Iijima S, Tanaka Y, Mizuguchi H
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Identification of flavonoid derivative that directly acts on hepatitis B virus surface protein and inhibits viral entry2015
- Author(s)
  Tsukuda S, Watashi K, Hamada Y, Isogawa M, Iwamoto M, Suzuki R, Aizaki H, Kojima S, Sugiyama M, Saito A, Tanaka Y, Mizokami M, Wakita T
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Molecular dissection of HBV evasion from restriction factor tetherin2015
- Author(s)
  Miyakawa K, Matsunaga S, Watashi K, Sugiyama M, Mizokami M, Wakita T, Ryo A
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Development of a novel vaccine platform based on Japanese encephalitis viruses2015
- Author(s)
  Suzuki R, Saga R, Fujimoto A, Watanabe N, Matsuda M, Hasegawa M, Watashi K, Aizaki H, Nakamura N, Konishi E, Kato T, Tajima S, Takasaki T, Takeyama H, Wakita T
- Organizer
  BMB 2015
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Identification of HBV entry inhibitors, based on the cyclosporin structure2015
- Author(s)
  Shimura S, Watashi K, Sluder A, Peel M, Kawai F, Sugiyama M, Park SY, Tanaka Y, Mizokami M, Wakita T
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Development of a novel vaccine platform based on Japanese encephalitis viruses2015
- Author(s)
  Suzuki R, Saga R, Fujimoto A, Watanabe N, Matsuda M, Hasegawa M, Watashi K, Aizaki H, Nakamura N, Konishi E, Kato T, Tajima S, Takasaki T, Takeyama H, Wakita T
- Organizer
  BMB 2015
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] A new fungi-derived vanitaracin A specifically inhibits the entry of hepatitis B and D viruses through interacting with NTCP2015
- Author(s)
  Kaneko M, Watashi K, Kamisuki S, Matsunaga H, Iwamoto M, Kawai F, Ohashi H, Tsukuda S, Shimura S, Suzuki R, Aizaki H, Sugiyama M, Park Sy, Ohtani N, Sugawara F, Tanaka Y, Mizokami M, Wakita T
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Chemical genetics for virus research: Interface of drug development and basic virology2015
- Author(s)
  Watashi K
- Organizer
  The 63rd Annual Meeting of the Japanese Society for Virology
- Place of Presentation
  福岡
- Year and Date
  2015-11-22
- Invited
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Investigation of the mechanism of interaction between host glycosylation system and hepatitis B virus replication system2015
- Author(s)
  Ito K, Yoneda M, Angata K, Watashi K, Wakita T, Iijima S, Tanaka Y, Tong S, Kuno A, Sugiyama M, Mizokami M, Narimatsu H
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] B型肝炎ウイルスの感染に対するRIG-Iを介した自然免疫応答機構2015
- Author(s)
  佐藤精一, 李凱, 亀山武志, 林隆也, 石田雄二, 村上周子, 渡邊綱正, 飯島沙幸, 櫻井遊, 渡士幸一, 堤進, 佐藤悠介, 秋田英万, 脇田隆字, Rice Cm, 原島秀吉, 小原道法, 田中靖人, 高岡晃教
- Organizer
  第25回抗ウイルス療法学会総会
- Place of Presentation
  東京
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] カイメン由来化合物metachromin A及びその類縁化合物の抗HBV活性の検討2015
- Author(s)
  山下篤哉, 田中智久, 葛西宏威, 渡士幸一, 脇田隆字, 外山政明, 馬場昌範, 前川伸哉, 榎本信幸, 玉城麻友美, 田中淳一, 森石恆司
- Organizer
  第25回抗ウイルス療法学会総会
- Place of Presentation
  東京
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Surfeit 4 is involved in HCV replication by interacting with NS4B2015
- Author(s)
  Kong L, Aoyagi H, Matsuda M, Fujimoto A, Watashi K, Suzuki R, Yamagoe S, Dohmae N, Suzuki T, Sakamaki Y, Ichinose S, Suzuki T, Wakita T, Aizaki H
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] NTCPを標的としたB型肝炎ウイルス感染阻害戦略2015
- Author(s)
  渡士幸一
- Organizer
  第31回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-07-02
- Invited
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Quantifying activity optimizes drug combinations against hepatitis C virus infection2015
- Author(s)
  Iwami S, Tanaka Y, Wakita T, Watashi K
- Organizer
  22nd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Strasbourg (France)
- Year and Date
  2015-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] C型肝炎治療薬の個性を探る～多剤併用から費用対効果の考察まで～2015
- Author(s)
  渡士幸一
- Organizer
  ウイルス感染現象における宿主細胞コンピテンシーの分子基盤第2回若手研究会
- Place of Presentation
  三浦
- Year and Date
  2015-07-18
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Long chain saturated fatty acid contributes to efficient egression of hepatitis B virus particles2015
- Author(s)
  Okamura H, Akahori Y, Kim S, Nio Y, Watashi K, Wakita T, Hijikata M
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Identification of HBV entry inhibitors, based on the cyclosporin structure2015
- Author(s)
  Shimura S, Watashi K, Sluder A, Peel M, Kawai F, Sugiyama M, Park SY, Tanaka Y, Mizokami M, Wakita T
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Metachromin A, sesquiterpene from marine sponge Dactylospongia metachromia, exerts anti-HBV activity via inhibition of HBV core promoter2015
- Author(s)
  Yamashita A, Tanaka T, Okuyama-Dobashi K, Kasai H, Watashi K, Wakita T, Toyama M, Baba M, Moriishi K
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Transfer hepatitis C virus from human liver cells to hepatic stellate cells2015
- Author(s)
  Zaitsu T, Aoyagi H, Fujimoto A, Matsuda M, Watanabe N, Watashi K, Suzuki R, Fukuhara T, Matsuura Y, Sakamaki Y, Ichinose S, Wake K, Suzuki T, Iijima H, Matsuura T, Tamura K, Wakita T, Aizaki H
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Identification of a new tricyclic polyketide, vanitaracin A, which inhibits the entry of HBV, HDV, and nucleoside analog-resistant HBV though targeting NTCP2015
- Author(s)
  Kaneko M, Watashi K, Kamisuki S, Matsunaga H, Iwamoto M, Kawai F, Ohashi H, Tsukuda S, Shimura S, Suzuki R, Aizaki H, Sugiyama M, Park SY, Ohtani N, Sugawara F, Tanaka Y, Mizokami M, Sureau C, Wakita T
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] SKIV2L-dependent HBV-RNA degradation by the RNA-exosome, a new anti-HBV host mechanism2015
- Author(s)
  Aly HH, Watashi K, Chayama K, Kato T, Wakita T
- Organizer
  2015 International Meeting of Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Bad Nauheim(Germany)
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Identification of neoechinulin B that represses liver X receptor-mediated transcription and inhibits hepatitis C virus replication2014
- Author(s)
  Nakajima S, Watashi K
- Organizer
  The 3rd International Symposium on Chemical Biology of Natural Products: Target ID and Regulation of Bioactivity
- Place of Presentation
  Osaka (Japan)
- Year and Date
  2014-10-28
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Microtubule-dependent hepatitis B virus (HBV) replication revealed by chemical screening on an efficient HBV-replicating cell line2014
- Author(s)
  Iwamoto M, Watashi K, Sugiyama M, Suzuki R, Aizaki H, Tanaka Y, Mizokami M, Ohtani N, Koiwai O, Wakita T
- Organizer
  2014 International Meeting on the Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Los Angeles (USA)
- Year and Date
  2014-09-04
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] B型肝炎ウイルス(HBV) large Sタンパク質とNTCPの相互作用阻害による抗HBV戦略2014
- Author(s)
  渡士幸一、Ann Sluder、松永智子、梁明秀、森下了、岩本将士、九十田千子、鈴木亮介、相崎英樹、Katyna Borroto-Esoda、田中靖人、楠原洋之、杉山真也、溝上雅史、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-12
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Development of hepatitis B virus cell culture system using immortalized human hepatocytes pruducing exogenous Na+/taurocholate cotransporting polypeptide2014
- Author(s)
  Akahori Y, Kato H, Fujita T, Watashi K, Wakita T, Hijikata M
- Organizer
  2014 International Meeting on the Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Los Angeles (USA)
- Year and Date
  2014-09-04
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] 宿主細胞における肝炎ウイルス感染増殖機構とこれを標的とした創薬2014
- Author(s)
  渡士幸一
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-16
- Invited
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] HBV感染受容体NTCPの発現調節機構の解析およびこれを阻害する低分子化合物の抗HBV効果2014
- Author(s)
  九十田千子、渡士幸一、岩本将士、鈴木亮介、相崎英樹、小嶋聡一、脇田隆字
- Organizer
  第24回抗ウイルス療法研究会総会
- Place of Presentation
  富士急
- Year and Date
  2014-05-09
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Microtubule-dependent hepatitis B virus (HBV) replication revealed by chemical screening on an efficient HBV-replicating cell line2014
- Author(s)
  Iwamoto M, Watashi K, Sugiyama M, Suzuki R, Aizaki H, Tanaka Y, Mizokami M, Ohtani N, Koiwai O, Wakita T
- Organizer
  2014 International Meeting on the Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Los Angeles (USA)
- Year and Date
  2014-09-04
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 培養系を用いた抗B型肝炎ウイルス化合物の同定と作用機序解析2014
- Author(s)
  渡士幸一、相崎英樹、脇田隆字
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2014-05-29
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] HBV感染受容体NTCPの発現調節機構の解析およびこれを阻害する低分子化合物の抗HBV効果2014
- Author(s)
  九十田千子、渡士幸一、岩本将士、鈴木亮介、相崎英樹、小嶋聡一、脇田隆字
- Organizer
  第24回抗ウイルス療法研究会総会
- Place of Presentation
  富士急
- Year and Date
  2014-05-09
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Prolactin regulatory element binding protein is involved in hepatitis C virus replication by interacting with NS4B2014
- Author(s)
  Lingbao Kong、青柳春代、松田麻未、藤本陽、渡士幸一、鈴木亮介、山越智、堂前直、鈴木健裕、鈴木哲朗、脇田隆字、相崎英樹
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] B型肝炎ウイルス(HBV)Lタンパク質とNTCPの相互作用阻害による抗HBV戦略2014
- Author(s)
  渡士幸一、Ann Sluder、松永智子、梁明秀、森下了、岩本将士、九十田千子、鈴木亮介、相崎英樹、Katyna Borroto-Esoda、田中靖人、楠原洋之、杉山真也、溝上雅史、脇田隆字
- Organizer
  第24回抗ウイルス療法研究会総会
- Place of Presentation
  富士急
- Year and Date
  2014-05-08
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] C型肝炎ウイルス生活環全体を標的とした新規作用を有する抗ウイルス剤の探索2014
- Author(s)
  脇田隆字、相崎英樹、渡士幸一
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2014-05-29
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] ウイルス感染培養系を基盤とした天然化合物の生理活性同定2014
- Author(s)
  中嶋翔、渡士幸一
- Organizer
  天然物ケミカルバイオロジー分子標的と活性制御第6回公開シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2014-05-28
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] ヒトiPS細胞由来分化誘導肝細胞を用いたB型肝炎ウイルス感染評価系の開発2014
- Author(s)
  山本達郎、櫻井文教、高山和雄、立花雅史、渡士幸一、脇田隆字、飯島沙幸、田中靖人、水口裕之
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] NS5A-associated membrane protein, embryonic lethal, abnormal vision, drosophila-like 1, regulates hepatitis C virus RNA synthesis and translation2014
- Author(s)
  Goto K, Fujimoto A, Watashi K, Suzuki R, Yamagoe S, Moriya K, Yotsuyanagi H, Koike K, Suzuki T, Miyamura T, Wakita T, Aizaki H
- Organizer
  21th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff (Canada)
- Year and Date
  2014-09-09
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Ruglation of hepatitis C virus replication by liver X receptor is disrupted by a fungi-derived neoechinulin B2014
- Author(s)
  Nakajima S, Watashi K, Kamisuki S, Takemoto K, Izaguirre-Carbonell J, Suzuki R, Aizaki H, Sugawara F, Wakita T
- Organizer
  21th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff (Canada)
- Year and Date
  2014-09-09
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] ヒトNTCP恒常発現不死化ヒト肝細胞を用いたB型肝炎ウイルス培養細胞感染系の構築2014
- Author(s)
  赤堀祐一、加藤博己、藤田尚志、渡士幸一、脇田隆字、土方誠
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Wheat germ cell-free system-based production of hepatitis B virus X (HBx) protein for generation and characterization of monoclonal antibody2014
- Author(s)
  Matsunaga S, Miyakawa K, Watashi K, Wakita T, Ryo A
- Organizer
  2014 International Meeting on the Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Los Angeles (USA)
- Year and Date
  2014-09-04
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] 低分子化合物を通して理解する肝炎ウイルス生活環2014
- Author(s)
  渡士幸一
- Organizer
  ウイルス学キャンプ in 湯河原
- Place of Presentation
  湯河原
- Year and Date
  2014-09-17
- Invited
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Wheat germ cell-free system-based production of hepatitis B virus X (HBx) protein for generation and characterization of monoclonal antibody2014
- Author(s)
  Matsunaga S, Miyakawa K, Watashi K, Wakita T, Ryo A
- Organizer
  2014 International Meeting on the Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Los Angeles (USA)
- Year and Date
  2014-09-04
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] レチノイド阻害剤はNTCP発現修飾を介して宿主細胞のB型肝炎ウイルス感染感受性を消失させる2014
- Author(s)
  九十田千子、渡士幸一、岩本将士、鈴木亮介、相崎英樹、小嶋聡一、杉山真也、田中靖人、溝上雅史、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-12
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] B型肝炎ウイルス感染を抑制するサイトカインの同定とその分子メカニズムの解析2014
- Author(s)
  渡士幸一
- Organizer
  Liver Forum in Kyoto
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Aryl hydrocarbon receptor による脂肪滴形成及び C 型肝炎ウイルス粒子構築の制御2014
- Author(s)
  大橋啓史、渡士幸一、中嶋翔、金ソルイ、鈴木亮介、相崎英樹、紙透伸治、菅原二三男、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Efficient HBV infection system in cell cultured cells2014
- Author(s)
  Fukasawa M, Shimizu Y, Shirasago Y, Iwamoto M, Watashi K, Tanaka Y, Wakita T, Kondoh M, Yagi K, Hanada K
- Organizer
  2014 International Meeting on the Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Los Angeles (USA)
- Year and Date
  2014-09-04
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] 新規 7-deazaneplanocin A 及び 7-deaza-8-azaneplanocin A 誘導体の抗 HBV 効果2014
- Author(s)
  外山政明、濱崎隆之、岡本実佳、渡士幸一、脇田隆字、馬場昌範
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Prolactin regulatory element binding protein is involved in hepatitis C virus replication by interacting with NS4B2014
- Author(s)
  Lingbao Kong、青柳春代、松田麻未、藤本陽、渡士幸一、鈴木亮介、山越智、堂前直、鈴木健裕、鈴木哲朗、脇田隆字、相崎英樹
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] トリプシン・EDTA による NTCP 依存 HBV 感染の増強2014
- Author(s)
  土橋香織、葛西宏威、田中智久、陳文家、渡士幸一、脇田隆字、山下篤哉、梁明秀、岡本徹、松浦善治、森石恆司
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] HBV感染による細胞内脂肪滴形成への影響2014
- Author(s)
  安本順、葛西宏威、土橋香織、山下篤哉、渡士幸一、脇田隆字、田中智久、森石恆司
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] ラパトアセッション - +鎖RNAウイルス -2014
- Author(s)
  渡士幸一
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-12
- Invited
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 宿主防御因子 Tetherin-BST2 によるB型肝炎ウイルス感染抑制とその回避機構の解明2014
- Author(s)
  宮川敬、松永智子、渡士幸一、杉山真也、溝上雅史、脇田隆字、梁明秀
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-12
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] B型肝炎ウイルス(HBV)Lタンパク質とNTCPの相互作用阻害による抗HBV戦略2014
- Author(s)
  渡士幸一、Ann Sluder、松永智子、梁明秀、森下了、岩本将士、九十田千子、鈴木亮介、相崎英樹、Katyna Borroto-Esoda、田中靖人、楠原洋之、杉山真也、溝上雅史、脇田隆字
- Organizer
  第24回抗ウイルス療法研究会総会
- Place of Presentation
  富士急
- Year and Date
  2014-05-08
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Japanese Encephalitis Virus-subviral particles harboring HCV neutralization epitopes induce neutralizing antibodies against HCV2014
- Author(s)
  Saga R, Fujimoto A, Watanabe N, Matsuda M, Hasegawa M, Watashi K, Aizaki H, Nakamura N, Konishi E, Kato T, Takeyama H, Wakita T, Suzuki R
- Organizer
  21th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff (Canada)
- Year and Date
  2014-09-09
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Development of hepatitis B virus cell culture system using immortalized human hepatocytes pruducing exogenous Na+/taurocholate cotransporting polypeptide2014
- Author(s)
  Akahori Y, Kato H, Fujita T, Watashi K, Wakita T, Hijikata M
- Organizer
  2014 International Meeting on the Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Los Angeles (USA)
- Year and Date
  2014-09-04
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] トリプシン・EDTA による NTCP 依存 HBV 感染の増強2014
- Author(s)
  土橋香織、葛西宏威、田中智久、陳文家、渡士幸一、脇田隆字、山下篤哉、梁明秀、岡本徹、松浦善治、森石恆司
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Aryl hydrocarbon receptor による脂肪滴形成及び C 型肝炎ウイルス粒子構築の制御2014
- Author(s)
  大橋啓史、渡士幸一、中嶋翔、金ソルイ、鈴木亮介、相崎英樹、紙透伸治、菅原二三男、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 低分子化合物を通して理解する肝炎ウイルス生活環2014
- Author(s)
  渡士幸一
- Organizer
  ウイルス学キャンプ in 湯河原
- Place of Presentation
  湯河原
- Year and Date
  2014-09-17
- Invited
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] グリチルリチンによる抗C型肝炎ウイルス作用 - phospholipase A2およびAutophagyによるHCV分泌過程の制御 -2014
- Author(s)
  青柳東代、相崎英樹、松本喜弘、鈴木亮介、渡士幸一、市野瀬志津子、松浦知和、鈴木哲朗、和氣健二郎、脇田隆字
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2014-05-29
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] グリチルリチンによる抗HCV作用 - phospholipase A2およびAutophagyによるC型肝炎ウイルス(HCV)分泌過程に与える影響 -2014
- Author(s)
  青柳東代、相崎英樹、藤本陽、松本喜弘、松田麻未、Su Su Hmwe、渡邉則幸、渡士幸一、鈴木亮介、市野瀬志津子、松浦知和、鈴木哲朗、和氣健二郎、脇田隆字
- Organizer
  第24回抗ウイルス療法研究会総会
- Place of Presentation
  富士急
- Year and Date
  2014-05-08
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 日本脳炎ウイルスおよびC 型肝炎ウイルス2価ワクチン抗原の発現と中和抗体の誘導2014
- Author(s)
  嵯峨涼平、藤本陽、渡邉則幸、松田麻未、長谷川慎、渡士幸一、相崎英樹、中村紀子、小西英二、加藤孝宣、田島茂、高崎智彦、竹山春子、脇田隆字、鈴木亮介
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-12
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Flutamide inhibits hepatitis C virus assembly through disrupting lipid droplets2014
- Author(s)
  Ohashi H, Watashi K, Nakajima S, Kim S, Suzuki R, Aizaki H, Kamisuki S, Sugawara F, Wakita T
- Organizer
  21th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff (Canada)
- Year and Date
  2014-09-09
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] B型肝炎ウイルス感染を抑制するサイトカインの同定とその分子メカニズムの解析2014
- Author(s)
  渡士幸一
- Organizer
  Liver Forum in Kyoto
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] B型肝炎ウイルス(HBV) large Sタンパク質とNTCPの相互作用阻害による抗HBV戦略2014
- Author(s)
  渡士幸一、Ann Sluder、松永智子、梁明秀、森下了、岩本将士、九十田千子、鈴木亮介、相崎英樹、Katyna Borroto-Esoda、田中靖人、楠原洋之、杉山真也、溝上雅史、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-12
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Japanese Encephalitis Virus-subviral particles harboring HCV neutralization epitopes induce neutralizing antibodies against HCV2014
- Author(s)
  Saga R, Fujimoto A, Watanabe N, Matsuda M, Hasegawa M, Watashi K, Aizaki H, Nakamura N, Konishi E, Kato T, Takeyama H, Wakita T, Suzuki R
- Organizer
  21th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff (Canada)
- Year and Date
  2014-09-09
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Single domain intrabodies against HCV core inhibit viral propagation and core-induced NF-kB activation2014
- Author(s)
  Suzuki R, Saito K, Matsuda M, Sato M, Kanegae Y, Watashi K, Aizaki H, Chiba J, Saito I, Wakita T, Suzuki T
- Organizer
  21th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff (Canada)
- Year and Date
  2014-09-09
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Efficient HBV infection system in cell cultured cells2014
- Author(s)
  Fukasawa M, Shimizu Y, Shirasago Y, Iwamoto M, Watashi K, Tanaka Y, Wakita T, Kondoh M, Yagi K, Hanada K
- Organizer
  2014 International Meeting on the Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Los Angeles (USA)
- Year and Date
  2014-09-04
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] C型肝炎ウイルス粒子の構築を阻害するflutamideの作用機序の解析2014
- Author(s)
  大橋啓史、渡士幸一、中嶋翔、金ソルイ、鈴木亮介、相崎英樹、紙透伸治、菅原二三男、脇田隆字
- Organizer
  第24回抗ウイルス療法研究会総会
- Place of Presentation
  富士急
- Year and Date
  2014-05-08
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 肝炎ウイルス生活環を標的とした抗ウイルス剤探索と分子基盤解明2014
- Author(s)
  渡士幸一
- Organizer
  平成26年度遺伝子病制御研究所研究集会　感染・免疫・炎症・発癌
- Place of Presentation
  札幌
- Year and Date
  2014-07-03
- Invited
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Anti-HBV Approach by Interfering the Interaction between HBV large surface protein and NTCP2014
- Author(s)
  Watashi K
- Organizer
  2nd Japan-Taiwan Research Symposium on Hepatitis B virus
- Place of Presentation
  Taipei (Taiwan)
- Year and Date
  2014-04-19
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] 宿主防御因子 Tetherin-BST2 によるB型肝炎ウイルス感染抑制とその回避機構の解明2014
- Author(s)
  宮川敬、松永智子、渡士幸一、杉山真也、溝上雅史、脇田隆字、梁明秀
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-12
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] ウイルス感染培養系を基盤とした天然化合物の生理活性同定2014
- Author(s)
  中嶋翔、渡士幸一
- Organizer
  天然物ケミカルバイオロジー分子標的と活性制御第6回公開シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2014-05-28
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] 遺伝子組換え酵母由来B型肝炎ウイルス様粒子の細胞表面への結合に関与する宿主因子の解析2014
- Author(s)
  松田麻未、鈴木亮介、嵯峨涼平、藤本陽、渡士幸一、相崎英樹、森石恆司、岡本徹、松浦善治、黒田俊一、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-12
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 効率的なHBV感染培養細胞系の構築に関する研究2014
- Author(s)
  深澤征義、清水芳実、白砂圭崇、岩本将士、渡士幸一、田中靖人、脇田隆字、近藤昌夫、八木清仁、花田賢太郎
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Identification of neoechinulin B that represses liver X receptor-mediated transcription and inhibits hepatitis C virus replication2014
- Author(s)
  Nakajima S, Watashi K
- Organizer
  The 3rd International Symposium on Chemical Biology of Natural Products: Target ID and Regulation of Bioactivity
- Place of Presentation
  Osaka (Japan)
- Year and Date
  2014-10-28
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] 宿主細胞における肝炎ウイルス感染増殖機構とこれを標的とした創薬2014
- Author(s)
  渡士幸一
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-16
- Invited
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] グリチルリチンによる抗C型肝炎ウイルス作用 - phospholipase A2およびAutophagyによるHCV分泌過程の制御 -2014
- Author(s)
  青柳東代、相崎英樹、松本喜弘、鈴木亮介、渡士幸一、市野瀬志津子、松浦知和、鈴木哲朗、和氣健二郎、脇田隆字
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2014-05-29
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] C型肝炎ウイルス粒子の構築を阻害するflutamideの作用機序の解析2014
- Author(s)
  大橋啓史、渡士幸一、中嶋翔、金ソルイ、鈴木亮介、相崎英樹、紙透伸治、菅原二三男、脇田隆字
- Organizer
  第24回抗ウイルス療法研究会総会
- Place of Presentation
  富士急
- Year and Date
  2014-05-08
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] C型肝炎ウイルス生活環全体を標的とした新規作用を有する抗ウイルス剤の探索2014
- Author(s)
  脇田隆字、相崎英樹、渡士幸一
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2014-05-29
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Characterization of a culture system reproducing the NTCP-mediated HBV entry and its application to drug development2014
- Author(s)
  Watashi K, Iwamoto M, Sluder A, Matsunaga S, Ryo A, Morishita R, Kwon ATJ, Suzuki H, Tsukuda S, Suzuki R, Aizaki H, Borroto-Esoda K, Sugiyama M, Tanaka Y, Mizokami M, Wakita T
- Organizer
  2014 International Meeting on the Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Los Angeles (USA)
- Year and Date
  2014-09-03
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] グリチルリチンによる抗HCV作用 - phospholipase A2およびAutophagyによるC型肝炎ウイルス(HCV)分泌過程に与える影響 -2014
- Author(s)
  青柳東代、相崎英樹、藤本陽、松本喜弘、松田麻未、Su Su Hmwe、渡邉則幸、渡士幸一、鈴木亮介、市野瀬志津子、松浦知和、鈴木哲朗、和氣健二郎、脇田隆字
- Organizer
  第24回抗ウイルス療法研究会総会
- Place of Presentation
  富士急
- Year and Date
  2014-05-08
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Maintenance of HCV infectivity by down-regulating hepatic lipase expression2014
- Author(s)
  Fujimoto A, Aizaki H, Matsuda M, Watanabe N, Watashi K, Suzuki R, Suzuki T, Wakita T
- Organizer
  21th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff (Canada)
- Year and Date
  2014-09-09
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Flutamide inhibits hepatitis C virus assembly through disrupting lipid droplets2014
- Author(s)
  Ohashi H, Watashi K, Nakajima S, Kim S, Suzuki R, Aizaki H, Kamisuki S, Sugawara F, Wakita T
- Organizer
  21th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff (Canada)
- Year and Date
  2014-09-09
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 海洋生物抽出物ライブラリーソースからのB型肝炎ウイルス転写活性抑制化合物の探索2014
- Author(s)
  山下篤哉、藤本雄介、田中智久、葛西宏威、児玉栄一、渡士幸一、脇田隆字、前川伸哉、榎本信幸、田中淳一、森石恆司
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] NS5A-associated membrane protein, embryonic lethal, abnormal vision, drosophila-like 1, regulates hepatitis C virus RNA synthesis and translation2014
- Author(s)
  Goto K, Fujimoto A, Watashi K, Suzuki R, Yamagoe S, Moriya K, Yotsuyanagi H, Koike K, Suzuki T, Miyamura T, Wakita T, Aizaki H
- Organizer
  21th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff (Canada)
- Year and Date
  2014-09-09
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] 肝炎ウイルス生活環を標的とした抗ウイルス剤探索と分子基盤解明2014
- Author(s)
  渡士幸一
- Organizer
  平成26年度遺伝子病制御研究所研究集会　感染・免疫・炎症・発癌
- Place of Presentation
  札幌
- Year and Date
  2014-07-03
- Invited
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Ruglation of hepatitis C virus replication by liver X receptor is disrupted by a fungi-derived neoechinulin B2014
- Author(s)
  Nakajima S, Watashi K, Kamisuki S, Takemoto K, Izaguirre-Carbonell J, Suzuki R, Aizaki H, Sugawara F, Wakita T
- Organizer
  21th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff (Canada)
- Year and Date
  2014-09-09
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Characterization of a culture system reproducing the NTCP-mediated HBV entry and its application to drug development2014
- Author(s)
  Watashi K, Iwamoto M, Sluder A, Matsunaga S, Ryo A, Morishita R, Kwon ATJ, Suzuki H, Tsukuda S, Suzuki R, Aizaki H, Borroto-Esoda K, Sugiyama M, Tanaka Y, Mizokami M, Wakita T
- Organizer
  2014 International Meeting on the Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Los Angeles (USA)
- Year and Date
  2014-09-03
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 培養系を用いた抗B型肝炎ウイルス化合物の同定と作用機序解析2014
- Author(s)
  渡士幸一、相崎英樹、脇田隆字
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2014-05-29
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 天然有機化合物 Neoechinulin B を利用した liver X receptor による C 型肝炎ウイルス産生制御機構の解析2014
- Author(s)
  中嶋翔、渡士幸一、紙透伸治、竹本健二、Jesus Izaguirre-Carbonell、鈴木亮介、相崎英樹、菅原二三男、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] 遺伝子組換え酵母由来B型肝炎ウイルス様粒子の細胞表面への結合に関与する宿主因子の解析2014
- Author(s)
  松田麻未、鈴木亮介、嵯峨涼平、藤本陽、渡士幸一、相崎英樹、森石恆司、岡本徹、松浦善治、黒田俊一、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-12
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Maintenance of HCV infectivity by down-regulating hepatic lipase expression2014
- Author(s)
  Fujimoto A, Aizaki H, Matsuda M, Watanabe N, Watashi K, Suzuki R, Suzuki T, Wakita T
- Organizer
  21th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff (Canada)
- Year and Date
  2014-09-09
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] ラパトアセッション - +鎖RNAウイルス -2014
- Author(s)
  渡士幸一
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-12
- Invited
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] 海洋生物抽出物ライブラリーソースからのB型肝炎ウイルス転写活性抑制化合物の探索2014
- Author(s)
  山下篤哉、藤本雄介、田中智久、葛西宏威、児玉栄一、渡士幸一、脇田隆字、前川伸哉、榎本信幸、田中淳一、森石恆司
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] HBV感染による細胞内脂肪滴形成への影響2014
- Author(s)
  安本順、葛西宏威、土橋香織、山下篤哉、渡士幸一、脇田隆字、田中智久、森石恆司
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] HBVカプシドタンパク質を標的とした新規抗HBV薬の探索2014
- Author(s)
  外山政明、濱崎隆之、岡本実佳、渡士幸一、脇田隆字、馬場昌範
- Organizer
  第24回抗ウイルス療法研究会総会
- Place of Presentation
  富士急
- Year and Date
  2014-05-08
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] ヒトiPS細胞由来分化誘導肝細胞を用いたB型肝炎ウイルス感染評価系の開発2014
- Author(s)
  山本達郎、櫻井文教、高山和雄、立花雅史、渡士幸一、脇田隆字、飯島沙幸、田中靖人、水口裕之
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 日本脳炎ウイルスおよびC 型肝炎ウイルス2価ワクチン抗原の発現と中和抗体の誘導2014
- Author(s)
  嵯峨涼平、藤本陽、渡邉則幸、松田麻未、長谷川慎、渡士幸一、相崎英樹、中村紀子、小西英二、加藤孝宣、田島茂、高崎智彦、竹山春子、脇田隆字、鈴木亮介
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-12
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] 効率的な B 型肝炎ウイルス(HBV)複製評価系を用いた微小管依存的な HBV 複製機構の解析2014
- Author(s)
  岩本将士、渡士幸一、杉山真也、鈴木亮介、相崎英樹、田中靖人、溝上雅史、大谷直子、小祝修、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-12
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] 効率的なHBV感染培養細胞系の構築に関する研究2014
- Author(s)
  深澤征義、清水芳実、白砂圭崇、岩本将士、渡士幸一、田中靖人、脇田隆字、近藤昌夫、八木清仁、花田賢太郎
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] ヒトNTCP安定発現によるB型肝炎ウイルス(HBV)感染許容性の獲得とそれを用いたHBV侵入機構の解析2014
- Author(s)
  岩本将士、渡士幸一、九十田千子、Hussein Aly、藤本陽、鈴木亮介、相崎英樹、脇田隆字、深澤征義、小祝修、楠原洋之
- Organizer
  第22回肝病態生理研究会
- Place of Presentation
  東京
- Year and Date
  2014-05-31
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] 天然有機化合物 Neoechinulin B を利用した liver X receptor による C 型肝炎ウイルス産生制御機構の解析2014
- Author(s)
  中嶋翔、渡士幸一、紙透伸治、竹本健二、Jesus Izaguirre-Carbonell、鈴木亮介、相崎英樹、菅原二三男、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 効率的な B 型肝炎ウイルス(HBV)複製評価系を用いた微小管依存的な HBV 複製機構の解析2014
- Author(s)
  岩本将士、渡士幸一、杉山真也、鈴木亮介、相崎英樹、田中靖人、溝上雅史、大谷直子、小祝修、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-12
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] The identification of a new interferon-independent host mechanism suppressing hepatitis B virus replication2014
- Author(s)
  Hussein Aly、渡士幸一、茶山一彰、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-12
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Single domain intrabodies against HCV core inhibit viral propagation and core-induced NF-kB activation2014
- Author(s)
  Suzuki R, Saito K, Matsuda M, Sato M, Kanegae Y, Watashi K, Aizaki H, Chiba J, Saito I, Wakita T, Suzuki T
- Organizer
  21th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff (Canada)
- Year and Date
  2014-09-09
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Retinoid inhibitors abolish the host permissiveness to HBV infection by modulating NTCP expression2014
- Author(s)
  Tsukuda S, Watashi K, Iwamoto M, Suzuki R, Aizaki H, Kojima S, Sugiyama M, Tanaka Y, Mizokami M, Wakita T
- Organizer
  2014 International Meeting on the Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Los Angeles (USA)
- Year and Date
  2014-09-04
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] HBVカプシドタンパク質を標的とした新規抗HBV薬の探索2014
- Author(s)
  外山政明、濱崎隆之、岡本実佳、渡士幸一、脇田隆字、馬場昌範
- Organizer
  第24回抗ウイルス療法研究会総会
- Place of Presentation
  富士急
- Year and Date
  2014-05-08
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] 新規 7-deazaneplanocin A 及び 7-deaza-8-azaneplanocin A 誘導体の抗 HBV 効果2014
- Author(s)
  外山政明、濱崎隆之、岡本実佳、渡士幸一、脇田隆字、馬場昌範
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] The identification of a new interferon-independent host mechanism suppressing hepatitis B virus replication2014
- Author(s)
  Hussein Aly、渡士幸一、茶山一彰、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-12
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] Retinoid inhibitors abolish the host permissiveness to HBV infection by modulating NTCP expression2014
- Author(s)
  Tsukuda S, Watashi K, Iwamoto M, Suzuki R, Aizaki H, Kojima S, Sugiyama M, Tanaka Y, Mizokami M, Wakita T
- Organizer
  2014 International Meeting on the Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Los Angeles (USA)
- Year and Date
  2014-09-04
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] Anti-HBV Approach by Interfering the Interaction between HBV large surface protein and NTCP2014
- Author(s)
  Watashi K
- Organizer
  2nd Japan-Taiwan Research Symposium on Hepatitis B virus
- Place of Presentation
  Taipei (Taiwan)
- Year and Date
  2014-04-19
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] ヒトNTCP恒常発現不死化ヒト肝細胞を用いたB型肝炎ウイルス培養細胞感染系の構築2014
- Author(s)
  赤堀祐一、加藤博己、藤田尚志、渡士幸一、脇田隆字、土方誠
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PUBLICLY-26102747
[Presentation] レチノイド阻害剤はNTCP発現修飾を介して宿主細胞のB型肝炎ウイルス感染感受性を消失させる2014
- Author(s)
  九十田千子、渡士幸一、岩本将士、鈴木亮介、相崎英樹、小嶋聡一、杉山真也、田中靖人、溝上雅史、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-12
- Data Source
  KAKENHI-PROJECT-26460565
[Presentation] PKR活性化制御を介するシクロフィリン阻害剤の新たな抗C型肝炎ウイルス作用機序2013
- Author(s)
  大東卓史、渡士幸一、Ann Sluder、中嶋翔、Katyna Borroto-Esoda、藤田尚志、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Cyclophilin inhibitors potentiate interferon signaling through diminished PKR phosphorylation in HCV-infected cells2013
- Author(s)
  K. Watashi, T. Daito, A. Sluder, K. Borroto-Esoda, T. Wakita
- Organizer
  European Association for the Study of the Liver 2013
- Place of Presentation
  Amsterdam(Netherlands)
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Cyclophilin inhibitors potentiate interferon signaling through diminished PKR phosphorylation in HCV-infected cells2013
- Author(s)
  K. Watashi, T. Daito, A. Sluder, K. Borroto-Esoda, T. Wakita
- Organizer
  European Association for the Study of the Liver 2013
- Place of Presentation
  Amsterdam(Netherlands)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] 肝炎ウイルス複製を阻害する低分子化合物／生理活性物質の同定とその作用機序2013
- Author(s)
  渡士幸一
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] B型肝炎ウイルス侵入阻害剤の同定およびそのNTCPを介した感染阻害機構の解明2013
- Author(s)
  九十田千子、渡士幸一、岩本将士、鈴木亮介、相崎英樹、小嶋聡一、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Tetherin/BST-2はHBV複製を負に制御する2013
- Author(s)
  古賀れい奈、宮川敬、松永智子、渡士幸一、脇田隆字、梁明秀
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Analysis of bioactivity of fungal-derived natural products based on a virus infection system2013
- Author(s)
  S. Nakajima, K. Watashi
- Organizer
  The 2nd International Symposium on Chemical Biology of Natural Products
- Place of Presentation
  Yokohama(Japan)
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] PhospholipaseA2およびAutophagyによるC型肝炎ウイルス(HCV)分泌過程の制御-グリチルリチンによる抗HCV作用-2013
- Author(s)
  青柳東代、相崎英樹、松本喜弘、松田麻未、SuSu Hmwe、渡邉則幸、渡士幸一、鈴木亮介、市野瀬志津子、松浦知和、鈴木哲朗、和気健二郎、宮村達男、脇田隆字
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] ウイルス感染系を基盤とした真菌由来天然化合物の生理活性探索2013
- Author(s)
  中嶋翔、渡士幸一
- Organizer
  天然物ケミカルバイオロジー第4回公開シンポジウム
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] C型肝炎ウイルスNS5A結合膜タンパク質ELAVL1のウイルス複製・翻訳スイッチング機構の解析2013
- Author(s)
  後藤耕司、相崎英樹、渡邉則幸、渡士幸一、鈴木亮介、山越智、四柳宏、森屋恭爾、小池和彦、鈴木哲朗、宮村達男、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] 細胞内発現抗体（イントラボディ）によるC型肝炎ウイルスの増殖抑制2013
- Author(s)
  松田麻未、斎藤憲司、鈴木亮介、佐藤充、鐘ヶ江裕美、渡士幸一、相崎英樹、千葉丈、斎藤泉、脇田隆字、鈴木哲朗
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] シチジンデアミナーゼAID誘導を介した抗B型肝炎ウイルス細胞内免疫応答機構の解明2013
- Author(s)
  渡士幸一、Guoxin Liang、岩本将士、丸澤宏之、喜多村晃一、村松正道、鈴木亮介、相崎英樹、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Liver X receptor転写活性および感染性C型肝炎ウイルス粒子産生を阻害する天然化合物の同定2013
- Author(s)
  中嶋翔、渡士幸一、紙透伸治、竹本健二、鈴木亮介、相崎英樹、菅原二三男、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Isolation of a natural product inhibiting the transcriptional activity of liver X receptor and reducing the production of infectious HCV2013
- Author(s)
  S. Nakajima, K. Watashi, S. Kamisuki, K. Takemoto, R. Suzuki, H. Aizaki, F. Sugawara, T. Wakita
- Organizer
  20th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Melbourne(Australia)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Mechanistic analysis on hepatitis B virus entry in an NTCP-overexpressing cell line2013
- Author(s)
  M. Iwamoto, K. Watashi, S. Tsukuda, H. Aly, R. Suzuki, H. Aizaki, O. Koiwai, H. Kusuhara, T. Wakita
- Organizer
  2013 International Meeting on Molecular Biology of Hepatitis B viruses
- Place of Presentation
  Shanghai(China)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Novel regulation mechanism of interferon signaling by cyclophilin through modulation of PKR in HCV-infected cells2013
- Author(s)
  K. Watashi, T. Daito, A. Sluder, K. Borroto-Esoda, T. Wakita
- Organizer
  20th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Melbourne(Australia)
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Dynamics of the cellular metabolome during hepatitis C virus infection – Regulation of the lipoprotein metabolisms by hepatic lipase -2013
- Author(s)
  A. Fujimoto, H. Aizaki, M. Matsuda, N. Watanabe, K. Watashi, R. Suzuki, T. Suzuki, T. Miyamura, T. Wakita
- Organizer
  20th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Melbourne(Australia)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Dynamics of the cellular metabolome during hepatitis C virus infection – Regulation of the lipoprotein metabolisms by hepatic lipase -2013
- Author(s)
  A. Fujimoto, H. Aizaki, M. Matsuda, N. Watanabe, K. Watashi, R. Suzuki, T. Suzuki, T. Miyamura, T. Wakita
- Organizer
  20th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Melbourne(Australia)
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Isolation of a natural product inhibiting the transcriptional activity of liver X receptor and reducing the production of infectious HCV2013
- Author(s)
  S. Nakajima, K. Watashi, S. Kamisuki, K. Takemoto, R. Suzuki, H. Aizaki, F. Sugawara, T. Wakita
- Organizer
  20th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Melbourne(Australia)
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] ヒトNTCP安定発現細胞株におけるB型肝炎ウイルス侵入機構の解析2013
- Author(s)
  岩本将士、渡士幸一、九十田千子、アリフセイン、鈴木亮介、相崎英樹、小祝修、楠原洋之、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] IL-1- and TNFalpha-triggered intracellular immune response against HBV2013
- Author(s)
  K. Watashi
- Organizer
  1st Japan-Taiwan Research Symposium on Hepatitis B virus
- Place of Presentation
  Tokyo(Japan)
- Invited
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] A retinoid derivative inhibits hepatitis B virus entry mediated by NTCP2013
- Author(s)
  S. Tsukuda, K. Watashi, M. Iwamoto, R. Suzuki, H. Aizaki, S. Kojima, T. Wakita
- Organizer
  2013 International Meeting on Molecular Biology of Hepatitis B viruses
- Place of Presentation
  Shanghai(China)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] 細胞内発現抗体（イントラボディ）によるC型肝炎ウイルスの増殖抑制2013
- Author(s)
  松田麻未、斎藤憲司、鈴木亮介、佐藤充、鐘ヶ江裕美、渡士幸一、相崎英樹、千葉丈、斎藤泉、脇田隆字、鈴木哲朗
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Tetherin/BST-2はHBV複製を負に制御する2013
- Author(s)
  古賀れい奈、宮川敬、松永智子、渡士幸一、脇田隆字、梁明秀
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Study of new virus/host interactions regulating HBV life cycle2013
- Author(s)
  フセインアリ、渡士幸一、茶山一彰、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] IL-1- and TNFalpha-triggered intracellular immune response against HBV2013
- Author(s)
  K. Watashi
- Organizer
  1st Japan-Taiwan Research Symposium on Hepatitis B virus
- Place of Presentation
  Tokyo(Japan)
- Invited
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting sodium taurocholate cotransporting polypeptide2013
- Author(s)
  K. Watashi, A. Sluder, S. Matsunaga, Ryo, S. Nakajima, M. Iwamoto, S. Tsukuda, K. Borroto-Esoda, M. Sugiyama, Y. Tanaka, M. Mizokami, T. Wakita
- Organizer
  2013 International Meeting on Molecular Biology of Hepatitis B viruses
- Place of Presentation
  Shanghai(China)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] C型肝炎ウイルス感染による宿主細胞の脂質代謝変化とHepatic Lipase発現制御2013
- Author(s)
  藤本陽、相崎英樹、松田麻未、渡邉則幸、渡士幸一、鈴木亮介、鈴木哲朗、宮村達男、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Interleukin-1 and tumor necrosis factor-alpha trigger restriction of hepatitis B virus infection via a cytidine deaminase AID2013
- Author(s)
  K. Watashi, G. Liang, M. Iwamoto, H. Marusawa, K. Kitamura, M. Muramatsu, R. Suzuki, J. Li, S. Tong, Y. Tanaka, K. Murata, H. Aizaki, T. Wakita
- Organizer
  2013 International Meeting on Molecular Biology of Hepatitis B viruses
- Place of Presentation
  Shanghai(China)
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] 数理モデルによる抗ウイルス薬の薬効評価系の確立2013
- Author(s)
  小泉吉輝、岩見真吾、内田奈々子、脇田隆字、渡士幸一
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Novel regulation mechanism of interferon signaling by cyclophilin through modulation of PKR in HCV-infected cells2013
- Author(s)
  Watashi, T. Daito, A. Sluder, K. Borroto-Esoda, T. Wakita
- Organizer
  20th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Melbourne(Australia)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] ウイルス感染系を基盤とした真菌由来天然化合物の生理活性探索2013
- Author(s)
  渡士幸一、中嶋翔
- Organizer
  天然物ケミカルバイオロジー第4回公開シンポジウム
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Interleukin-1 and tumor necrosis factor-alpha trigger restriction of hepatitis B virus infection via a cytidine deaminase AID2013
- Author(s)
  K. Watashi, G. Liang, M. Iwamoto, H. Marusawa, K. Kitamura, M. Muramatsu, R. Suzuki, J. Li, S. Tong, Y. Tanaka, K. Murata, H. Aizaki, T. Wakita
- Organizer
  2013 International Meeting on Molecular Biology of Hepatitis B viruses
- Place of Presentation
  Shanghai(China)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] 肝炎ウイルス複製を阻害する低分子化合物/生理活性物質の同定とその作用機序2013
- Author(s)
  渡士幸一
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] PKR活性化制御を介するシクロフィリン阻害剤の新たな抗C型肝炎ウイルス作用機序2013
- Author(s)
  大東卓史、渡士幸一、Ann Sluder、中嶋翔、Katyna Borroto-Esoda、藤田尚志、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] PhospholipaseA2およびAutophagyによるC型肝炎ウイルス(HCV)分泌過程の制御-グリチルリチンによる抗HCV作用-2013
- Author(s)
  青柳東代、相崎英樹、松本喜弘、松田麻未、SuSu Hmwe、渡邉則幸、渡士幸一、鈴木亮介、市野瀬志津子、松浦知和、鈴木哲朗、和気健二郎、宮村達男、脇田隆字
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] B型肝炎ウイルス侵入阻害剤の同定およびそのNTCPを介した感染阻害機構の解明2013
- Author(s)
  九十田千子、渡士幸一、岩本将士、鈴木亮介、相崎英樹、小嶋聡一、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] The discovery of a new virus/host interaction regulating HBV life cycle2013
- Author(s)
  H. Aly, K. Watashi, K. Chayama, T. Wakita
- Organizer
  2013 International Meeting on Molecular Biology of Hepatitis B viruses
- Place of Presentation
  Shanghai(China)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Formation of covalently closed circular (ccc)DNA tetracycline inducible HBV expression cell line2013
- Author(s)
  N. Ogura, K. Watashi, T. Wakita
- Organizer
  2013 International Meeting on Molecular Biology of Hepatitis B viruses
- Place of Presentation
  Shanghai(China)
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] ヒトNTCP安定発現細胞株におけるB型肝炎ウイルス侵入機構の解析2013
- Author(s)
  岩本将士、渡士幸一、九十田千子、アリフセイン、鈴木亮介、相崎英樹、小祝修、楠原洋之、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] A retinoid derivative inhibits hepatitis B virus entry mediated by NTCP2013
- Author(s)
  S. Tsukuda, K. Watashi, M. Iwamoto, R. Suzuki, H. Aizaki, S. Kojima, T. Wakita
- Organizer
  2013 International Meeting on Molecular Biology of Hepatitis B viruses
- Place of Presentation
  Shanghai(China)
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] 日本脳炎ウイルスレプリコンを用いたトランスパッケージング型1回感染性フラビウイルス粒子産生系の開発2013
- Author(s)
  鈴木亮介、石川知弘、小西英二、嵯峨涼平、松田麻未、渡士幸一、相崎英樹、高崎智彦、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] 新規ピラノンカルボキサミド誘導体の抗HCV効果とその構造活性相関2013
- Author(s)
  馬場昌範、外山政明、伊藤渉、岡本実佳、渡士幸一、脇田隆字、Sharon Ashoke
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Analysis of bioactivity of fungal-derived natural products based on a virus infection system2013
- Author(s)
  S. Nakajima, K. Watashi
- Organizer
  The 2nd International Symposium on Chemical Biology of Natural Products
- Place of Presentation
  Yokohama(Japan)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting sodium taurocholate cotransporting polypeptide2013
- Author(s)
  K. Watashi, A. Sluder, S. Matsunaga, A. Ryo, S. Nakajima, M. Iwamoto, S. Tsukuda, K. Borroto-Esoda, M. Sugiyama, Y. Tanaka, M. Mizokami, T. Wakita
- Organizer
  2013 International Meeting on Molecular Biology of Hepatitis B viruses
- Place of Presentation
  Shanghai(China)
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Liver X receptor転写活性および感染性C型肝炎ウイルス粒子産生を阻害する天然化合物の同定2013
- Author(s)
  中嶋翔、渡士幸一、紙透伸治、竹本健二、鈴木亮介、相崎英樹、菅原二三男、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] 日本脳炎ウイルスレプリコンを用いたトランスパッケージング型1回感染性フラビウイルス粒子産生系の開発2013
- Author(s)
  鈴木亮介、石川知弘、小西英二、嵯峨涼平、松田麻未、渡士幸一、相崎英樹、高崎智彦、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Mechanistic analysis on hepatitis B virus entry in an NTCP-overexpressing cell line2013
- Author(s)
  M. Iwamoto, K. Watashi, S. Tsukuda, H. Aly, R. Suzuki, H. Aizaki, O. Koiwai, H. Kusuhara, T. Wakita
- Organizer
  2013 International Meeting on Molecular Biology of Hepatitis B viruses
- Place of Presentation
  Shanghai(China)
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] プラスミドトランスフェクションによるトランスパッケージング型1回感染性フラビウイルス産生系の確立2013
- Author(s)
  鈴木亮介、石川知弘、小西英二、嵯峨涼平、松田麻未、渡士幸一、相崎英樹、高崎智彦、脇田隆字
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] C型肝炎ウイルスNS5A結合膜タンパク質ELAVL1のウイルス複製・翻訳スイッチング機構の解析2013
- Author(s)
  後藤耕司、相崎英樹、渡邉則幸、渡士幸一、鈴木亮介、山越智、四柳宏、森屋恭爾、小池和彦、鈴木哲朗、宮村達男、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] C型肝炎ウイルス分泌過程はphospholipase Dが関わる膜輸送により制御される2013
- Author(s)
  内田奈々子、渡士幸一、中嶋翔、岩本将士、鈴木亮介、相崎英樹、千葉丈、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Formation of covalently closed circular (ccc)DNA tetracycline inducible HBV expression cell line2013
- Author(s)
  N. Ogura, K. Watashi, T. Wakita
- Organizer
  2013 International Meeting on Molecular Biology of Hepatitis B viruses
- Place of Presentation
  Shanghai(China)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] PhospholipaseA2およびAutophagyによるC型肝炎ウイルス(HCV)分泌過程の制御-グリチルリチンによる抗HCV作用-2013
- Author(s)
  青柳東代、相崎英樹、松本喜弘、松田麻未、SuSu Hmwe、渡邉則幸、渡士幸一、鈴木亮介、市野瀬志津子、松浦知和、鈴木哲朗、和気健二郎、宮村達男、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] シチジンデアミナーゼAID誘導を介した抗B型肝炎ウイルス細胞内免疫応答機構の解明2013
- Author(s)
  渡士幸一、Guoxin Liang、岩本将士、丸澤宏之、喜多村晃一、村松正道、鈴木亮介、相崎英樹、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] 新規ピラノンカルボキサミド誘導体の抗HCV効果とその構造活性相関2013
- Author(s)
  馬場昌範、外山政明、伊藤渉、岡本実佳、渡士幸一、脇田隆字、Sharon Ashoke
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] PhospholipaseA2およびAutophagyによるC型肝炎ウイルス(HCV)分泌過程の制御-グリチルリチンによる抗HCV作用-2013
- Author(s)
  青柳東代、相崎英樹、松本喜弘、松田麻未、SuSu Hmwe、渡邉則幸、渡士幸一、鈴木亮介、市野瀬志津子、松浦知和、鈴木哲朗、和気健二郎、宮村達男、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] C型肝炎ウイルス分泌過程はphospholipase Dが関わる膜輸送により制御される2013
- Author(s)
  内田奈々子、渡士幸一、中嶋翔、岩本将士、鈴木亮介、相崎英樹、千葉丈、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] 数理モデルによる抗ウイルス薬の薬効評価系の確立2013
- Author(s)
  小泉吉輝、岩見真吾、内田奈々子、脇田隆字、渡士幸一
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] IL-1- and TNFalpha-triggered intracellular immune response against HBV2013
- Author(s)
  K. Watashi
- Organizer
  1^<st> Japan-Taiwan Research Symposium on Hepatitis B virus
- Place of Presentation
  Tokyo(Japan)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] 肝炎ウイルス複製を阻害する低分子化合物／生理活性物質の同定とその作用機序2013
- Author(s)
  渡士幸一
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] 細胞内発現抗体(イントラボディ)によるC型肝炎ウイルスの増殖抑制2013
- Author(s)
  松田麻未、斎藤憲司、鈴木亮介、佐藤充、鐘ヶ江裕美、渡士幸一、相崎英樹、千葉丈、斎藤泉、脇田隆字、鈴木哲朗
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] プラスミドトランスフェクションによるトランスパッケージング型1回感染性フラビウイルス産生系の確立2013
- Author(s)
  鈴木亮介、石川知弘、小西英二、嵯峨涼平、松田麻未、渡士幸一、相崎英樹、高崎智彦、脇田隆字
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Study of new virus/host interactions regulating HBV life cycle2013
- Author(s)
  フセインアリ、渡士幸一、茶山一彰、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Dynamics of the cellular metabolome during hepatitis C virus infection–Regulation of the lipoprotein metabolisms by hepatic lipase -2013
- Author(s)
  A. Fujimoto, H. Aizaki, M. Matsuda, N. Watanabe, K. Watashi, R. Suzuki, T. Suzuki, T. Miyamura, T. Wakita
- Organizer
  20th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Melbourne(Australia)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] The discovery of a new virus/host interaction regulating HBV life cycle2013
- Author(s)
  H. Aly, K. Watashi, K. Chayama, T. Wakita
- Organizer
  2013 International Meeting on Molecular Biology of Hepatitis B viruses
- Place of Presentation
  Shanghai(China)
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] C型肝炎ウイルス感染による宿主細胞の脂質代謝変化とHepatic Lipase発現制御2013
- Author(s)
  藤本陽、相崎英樹、松田麻未、渡邉則幸、渡士幸一、鈴木亮介、鈴木哲朗、宮村達男、脇田隆字
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Phospholipase D regulates membrane trafficking during hepatitis C virus egress2012
- Author(s)
  N. Uchida, K. Watashi, R. Suzuki, H. Aizaki, J. Chiba, T. Wakita
- Organizer
  19th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Venice(Italy)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] IL-1およびTNF-alphaのB型肝炎ウイルス感染阻害効果2012
- Author(s)
  渡士幸一、内田奈々子、大東卓史、清原知子、鈴木亮介、相崎英樹、脇田隆字
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Development of cell clones for analyzing anti-hepatitis B virus compounds2012
- Author(s)
  K. Watashi, M. Iwamoto, N. Uchida, T. Kiyohara, R. Suzuki, H. Aizaki, T. Wakita
- Organizer
  2012 International Meeting on Molecular Biology of Hepatitis B viruses
- Place of Presentation
  Oxford (England)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] 数理モデルを用いた肝炎ウイルスの解析2012
- Author(s)
  渡士幸一
- Organizer
  第22回数理生物学会
- Place of Presentation
  岡山
- Year and Date
  2012-09-10
- Invited
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Interleukin-1 and tumor necrosis factor-alpha suppressed hepatitis B virus infection through NF-kappaB signaling pathway2012
- Author(s)
  K. Watashi, N. Uchida, T. Daito, T. Kiyohara, R. Suzuki, H. Aizaki, T. Wakita
- Organizer
  2012 International Meeting on Molecular Biology of Hepatitis B viruses
- Place of Presentation
  Oxford(England)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Phospholipase D is a cellular regulator during hepatitis C virus egress and a possible target for antiviral strategy2012
- Author(s)
  K. Watashi, N. Uchida, R. Suzuki, H. Aizaki, T. Wakita
- Organizer
  Japan Society of Hepatology 10th Single Topic Conference
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] An alternative endocytosis pathway for the protective entry of hepatitis C virus2012
- Author(s)
  R. Suzuki, M. Matsuda, K. Watashi, H. Aizaki, Y. Matsuura, T. Suzuki, T. Wakita
- Organizer
  19th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Venice (Italy)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Identification of natural products inhibiting hepatitis C virus infection2012
- Author(s)
  S. Nakajima, K. Watashi
- Organizer
  The 1st International Symposium on Chemical Biology of Natural Products
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Construction of hepatitis C virus genotype 4a clone2012
- Author(s)
  H.H. Aly, K. Watashi, N. Watanabe, M. Mizokami, T. Kato, T. Wakita
- Organizer
  19th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Venice (Italy)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Interleukin-1 and tumor necrosis factor-alpha suppressed hepatitis B virus infection through NFkappaB signaling pathway2012
- Author(s)
  K. Watashi, N. Uchida, T. Daito, T. Kiyohara, R. Suzuki, H. Aizaki, T. Wakita
- Organizer
  2012 International Meeting on Molecular Biology of Hepatitis B viruses
- Place of Presentation
  Oxford (England)
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Synthetic studies of MA026, a novel antiviral lipocyclodepsipeptide2012
- Author(s)
  S. Shimura, M. Ishima, I. Ota, E. Tsutsui, S. kamisuki, H. Murata, T. Yamazaki, T. Suzuki, K. Kuramochi, T. Takeuchi, K. Watashi, S. Kobayashi, F. Sugawara
- Organizer
  International Congress on Natural Products Research 2012
- Place of Presentation
  New York (USA)
- Year and Date
  2012-07-28
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Identification of natural products inhibiting hepatitis C virus infection2012
- Author(s)
  S. Nakajima, K. Watashi
- Organizer
  The 1st International Symposium on Chemical Biology of Natural Products
- Place of Presentation
  Kyoto(Japan)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] An alternative endocytosis pathway for the protective entry of hepatitis C virus2012
- Author(s)
  R. Suzuki, M. Matsuda, K. Watashi, H. Aizaki, Y. Matsuura, T. Suzuki, T. Wakita
- Organizer
  19th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Venice(Italy)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Interleukin-1 and tumor necrosis factor-alpha suppressed hepatitis B virus infection through NF-kappaB signaling pathway2012
- Author(s)
  K. Watashi, N. Uchida, T. Daito, T. Kiyohara, R. Suzuki, H. Aizaki, T. Wakita
- Organizer
  2012 International Meeting on Molecular Biology of Hepatitis B viruses
- Place of Presentation
  Oxford (England)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Identification of natural products inhibiting hepatitis C virus infection2012
- Author(s)
  S. Nakajima, K. Watashi
- Organizer
  The 1st International Symposium on Chemical Biology of Natural Products
- Place of Presentation
  京都
- Year and Date
  2012-10-31
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] 数理モデルを用いた肝炎ウイルスの解析2012
- Author(s)
  渡士幸一
- Organizer
  第22回数理生物学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] IL-1およびTNF-alphaのB型肝炎ウイルス感染阻害効果2012
- Author(s)
  渡士幸一、内田奈々子、大東卓史、清原知子、鈴木亮介、相崎英樹、脇田隆字
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2012-11-13
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Phospholipase D regulates membrane trafficking during hepatitis C virus egress2012
- Author(s)
  N. Uchida, K. Watashi, R. Suzuki, H. Aizaki, J. Chiba, T. Wakita
- Organizer
  19th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Venice (Italy)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Development of cell clones for analyzing anti-hepatitis B virus compounds2012
- Author(s)
  K. Watashi, M. Iwamoto, N. Uchida, T. Kiyohara, R. Suzuki, H. Aizaki, T. Wakita
- Organizer
  2012 International Meeting on Molecular Biology of Hepatitis B viruses
- Place of Presentation
  Oxford (England)
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Construction of hepatitis C virus genotype 4a clone2012
- Author(s)
  H.H. Aly, K. Watashi, N. Watanabe, M. Mizokami, T. Kato, T. Wakita
- Organizer
  19th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Venice(Italy)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] 抗HBV剤探索とHBV感染増殖機構の解析2012
- Author(s)
  渡士幸一
- Organizer
  LIVER2012 第8回肝免疫ウイルスフロンティア　肝疾患研究の新潮流
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Synthetic studies of MA026, a novel antiviral lipocyclodepsipeptide2012
- Author(s)
  S. Shimura, M. Ishima, I. Ota, E. Tsutsui, S. kamisuki, H. Murata, T. Yamazaki, T. Suzuki, K. Kuramochi, T. Takeuchi, K. Watashi, S. Kobayashi, F. Sugawara
- Organizer
  International Congress on Natural Products Research 2012
- Place of Presentation
  New York (USA)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Development of cell clones for analyzing anti-hepatitis B virus compounds2012
- Author(s)
  K. Watashi, M. Iwamoto, N. Uchida, T. Kiyohara, R. Suzuki, H. Aizaki, T. Wakita
- Organizer
  2012 International Meeting on Molecular Biology of Hepatitis B viruses
- Place of Presentation
  Oxford(England)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Characterization of anti-HCV release inhibitors targeting phospholipase D2012
- Author(s)
  K. Watashi, N. Uchida, M. Saeed, R. Suzuki, H. Aizaki, T. Wakita
- Organizer
  19th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Venice(Italy)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Antiviral activity of glycyrrhizin against hepatitis C virus in vitro2012
- Author(s)
  Y. Matsumoto, N. Watanabe, K. Watashi, R. Suzuki, T. Matsuura, T. Suzuki, T. Miyamura, K. Wake, T. Wakita, H. Aizaki
- Organizer
  19th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Venice(Italy)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Phospholipase D regulates membrane trafficking during hepatitis C virus egress2012
- Author(s)
  N. Uchida, K. Watashi, R. Suzuki, H. Aizaki, J. Chiba, T. Wakita
- Organizer
  19th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Venice (Italy)
- Year and Date
  2012-10-05
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Antiviral activity of glycyrrhizin against hepatitis C virus in vitro2012
- Author(s)
  Y. Matsumoto, N. Watanabe, K. Watashi, R. Suzuki, T. Matsuura, T. Suzuki, T. Miyamura, K. Wake, T. Wakita, H. Aizaki
- Organizer
  19th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Venice (Italy)
- Year and Date
  2012-10-05
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] 抗HBV剤探索とHBV感染増殖機構の解析2012
- Author(s)
  渡士幸一
- Organizer
  LIVER2012第8回肝免疫・ウイルス・フロンティア肝疾患研究の新潮流
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Characterization of anti-HCV release inhibitors targeting phospholipase D2012
- Author(s)
  K. Watashi, N. Uchida, M. Saeed, R. Suzuki, H. Aizaki, T. Wakita
- Organizer
  19th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Venice (Italy)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Characterization of anti-HCV release inhibitors targeting phospholipase D2012
- Author(s)
  K. Watashi, N. Uchida, M. Saeed, R. Suzuki, H. Aizaki, T. Wakita
- Organizer
  19th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Venice (Italy)
- Year and Date
  2012-10-05
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Synthetic studies of MA026, a novel antiviral lipocyclodepsipeptide2012
- Author(s)
  S. Shimura, M. Ishima, I. Ota, E. Tsutsui, S. kamisuki, H. Murata, T. Yamazaki, T. Suzuki, K. Kuramochi, T. Takeuchi, K. Watashi, S. Kobayashi, F. Sugawara
- Organizer
  International Congress on Natural Products Research 2012
- Place of Presentation
  New York(USA)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] 抗HBV剤探索とHBV感染増殖機構の解析2012
- Author(s)
  渡士幸一
- Organizer
  LIVER2012 第8回肝免疫・ウイルス・フロンティア　肝疾患研究の新潮流
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] 低分子化合物を利用した肝炎ウイルス学解析2012
- Author(s)
  渡士幸一
- Organizer
  東京大学医科学研究所第一回感染症国際研究センターシンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Phospholipase D is a cellular regulator during hepatitis C virus egress and a possible target for antiviral strategy2012
- Author(s)
  K. Watashi, N. Uchida, R. Suzuki, H. Aizaki, T. Wakita
- Organizer
  Japan Society of Hepatology 10th Single Topic Conference
- Place of Presentation
  東京
- Year and Date
  2012-11-21
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Construction of hepatitis C virus genotype 4a clone2012
- Author(s)
  H.H. Aly, K. Watashi, N. Watanabe, M. Mizokami, T. Kato, T. Wakita
- Organizer
  19th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Venice (Italy)
- Year and Date
  2012-10-05
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] An alternative endocytosis pathway for the protective entry of hepatitis C virus2012
- Author(s)
  R. Suzuki, M. Matsuda, K. Watashi, H. Aizaki, Y. Matsuura, T. Suzuki, T. Wakita
- Organizer
  19th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Venice (Italy)
- Year and Date
  2012-10-05
- Data Source
  KAKENHI-PUBLICLY-24102537
[Presentation] Phospholipase D is a cellular regulator during hepatitis C virus egress and a possible target for antiviral strategy2012
- Author(s)
  K. Watashi, N. Uchida, R. Suzuki, H. Aizaki, T. Wakita
- Organizer
  Japan Society of Hepatology 10th Single Topic Conference
- Place of Presentation
  Tokyo(Japan)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Antiviral activity of glycyrrhizin against hepatitis C virus in vitro2012
- Author(s)
  Y. Matsumoto, N. Watanabe, K. Watashi, R. Suzuki, T. Matsuura, T. Suzuki, T. Miyamura, K. Wake, T. Wakita, H. Aizaki
- Organizer
  19th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Venice (Italy)
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Halopemide inhibited a post-assembly step in hepatitis C virus life cycle2011
- Author(s)
  N. Uchida, K. Watashi, R. Suzuki, H. Aizaki, J. Chiba, T. Wakita
- Organizer
  18th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Identification of small molecules affecting late steps of hepatitis C virus life cycle2011
- Author(s)
  Watashi K, Uchida N, Suzuki R, Aizaki H, Wakita T
- Organizer
  International Union of Microbiological Societies 2011 Congress
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Identification of a host factor that interacts with hepatitis C virus NS2 protein and is involved in the viral assembly2011
- Author(s)
  Suzuki R, Suzuki T, Saito K, Matsuda M, Watashi K, Matsuura Y, Wakita T, Aizaki H
- Organizer
  International Union of Microbiological Societies 2011 Congress
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] 低分子化合物を利用した肝炎ウイルス学解析2011
- Author(s)
  渡士幸一
- Organizer
  感染・免疫・炎症・発癌シンポジウム(招待講演)
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] 数理モデルと肝炎ウイルス解析2011
- Author(s)
  渡士幸一
- Organizer
  第8回生物数学の理論とその応用
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Identification of lipid droplet-associated membrane proteins that are involved in HCV production2011
- Author(s)
  H. Aizaki, Y. Matsumoto, K. Goto, K. Watashi, R. Suzuki, M. Fukasawa, K. Hanada, S. Sato, N. Takahashi, Y. Matsuura, K. Motojima, T. Miyamura, T. Suzuki, T. Wakita
- Organizer
  18th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Identification and functional analysis of small molecules inhibiting the late step of hepatitis C virus life cycle2011
- Author(s)
  K. Watashi, N. Uchida, R. Suzuki, H. Aizaki, T. Wakita
- Organizer
  18th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Identification of a novel cellular RNA helicase-like protein as a target for cyclosporin A that is involved in hepatitis C virus genome replication2011
- Author(s)
  K. Watashi, H. Sahara, K. Morohashi, K. Iwabata, T. Sunoki, K. Kuramochi, K. Takakusagi, H. Miyashita, N. Sato, A. Tanabe, K. Shimotohno, S. Kobayashi, K. Sakaguchi, F. Sugawara
- Organizer
  18th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] 数理モデルと肝炎ウイルス解析2011
- Author(s)
  渡士幸一
- Organizer
  第8回生物数学の理論とその応用(招待講演)
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Identification of novel NS5A-associated proteins in the host-cell membrane fraction and their role in HCV life cycle2011
- Author(s)
  Goto K, Kimura T, Watashi K, Suzuki R, Yamagoe S, Miyamura T, Moriya K, Yotsuyanagi H, Koike K, Suzuki T, Wakita T, Aizaki H
- Organizer
  18th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Identification of small molecules affecting late steps of hepatitis C virus life cycle2011
- Author(s)
  K. Watashi, N. Uchida, R. Suzuki, H. Aizaki, T. Wakita
- Organizer
  International Union of Microbiological Societies 2011 Congress
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Signal peptidase complex 1 participates in the assembly of hepatitis C virus through an interaction with NS22011
- Author(s)
  R. Suzuki, T. Suzuki, K. Saito, M. Matsuda, K. Watashi, Y. Matsuura, T. Wakita, H. Aizaki
- Organizer
  18th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] 低分子化合物を利用した肝炎ウイルス学解析2011
- Author(s)
  渡士幸一
- Organizer
  感染・免疫・炎症・発癌
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Antiviral activity of glycyrrhizin against hepatitis C virus in vitro2011
- Author(s)
  Matsumoto Y, Watashi K, Suzuki R, Matsuura T, Suzuki T, Miyamura T, Wake K, Wakita T, Aizaki H. Antiviral activity of glycyrrhizin against hepatitis C virus in vitro
- Organizer
  International Union of Microbiological Societies 2011 Congress
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Screening of small molecules affecting the production of hepatitis B virus2011
- Author(s)
  K. Watashi, N. Uchida, R. Suzuki, H. Aizaki, T. Wakita
- Organizer
  2011 International Meeting on Molecular Biology of Hepatitis B viruses
- Place of Presentation
  Lake Buena Vista, USA
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Identification of novel NS5A-associated proteins in the host-cell membrane fraction and their International Symposium on hepatitis C virus and related viruses2011
- Author(s)
  K. Goto, T. Kimura, K. Watashi, R. Suzuki, S. Yamagoe, T. Miyamura, K. Moriya, H. Yotsuyanagi, K. Koike, T. Suzuki, T. Wakita, H. Aizaki
- Organizer
  18th International Symposium on hepatitis C virus and related viruses
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Identification of a host factor that interacts with hepatitis C virus NS2 protein and is involved in the viral assembly2011
- Author(s)
  R. Suzuki, T. Suzuki, K. Saito, M. Matsuda, K. Watashi, Y. Matsuura, T. Wakita, H. Aizaki
- Organizer
  International Union of Microbiological Societies 2011 Congress
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] Antiviral activity of glycyrrhizin against hepatitis C virus in vitro2011
- Author(s)
  Y. Matsumoto, K. Watashi, R. Suzuki, T. Matsuura, T. Suzuki, T. Miyamura, K. Wake, T. Wakita, H. Aizaki
- Organizer
  International Union of Microbiological Societies 2011 Congres
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-23790514
[Presentation] ヒトNTCP安定発現によるB型肝炎ウイルス(HBV)感染許容性の獲得とそれを用いたHBV侵入機構の解析
- Author(s)
  岩本将士、渡士幸一、九十田千子、Hussein Aly、藤本陽、鈴木亮介、相崎英樹、脇田隆字、深澤征義、小祝修、楠原洋之
- Organizer
  第22回肝病態生理研究会
- Place of Presentation
  東京
- Year and Date
  2014-05-30 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-26460565
[]

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Watashi Koichi 渡士 幸一

WATASHI Koichi 渡士 幸一

渡士 幸一 ワタシ コウイチ

Research Projects

Research Products

Co-Researchers

Regulation of hepatitis B virus entry by the receptor complex and its significance in determination of host tropismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural biology of the hepatitis B virus entry and its inhibition

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structure and functional analysis of the SARS-CoV-2 Nucleocapsid Protein

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism, dynamics, and interaction with environment in the hepatitis B virus entry systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanistic analysis of hepatitis B virus entry and the host factors using new cell culture systemsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Systems Virology for understanding viral pathogenesis

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

ウイルス感染増殖系を基盤とした天然化合物新規生理機能の同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of regulation mechanisms of hepatitis B virus life cycle by kinases and post-translational modificationsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

肝炎ウイルス感染増殖系を用いた天然物生理活性解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanistic analysis of hepatitis C virus life cycle using small moleculesPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

シクロスポリンを用いたC型肝炎ウイルスゲノム複製機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Encyclopedia of Signaling Molecules, 2nd Edition2017

Author(s)

Publisher

Data Source

[Book] Encyclopedia of Signaling Molecules, 2nd Edition2017

Author(s)

Publisher

Data Source

Watashi Koichi 渡士幸一

WATASHI Koichi 渡士幸一

渡士幸一ワタシコウイチ