ARAHORI Hitomi 荒堀仁美

… Alternative Names

Researcher Number	40379186
Other IDs
Affiliation (Current)	2021: 大阪大学, 医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2017 – 2020: 大阪大学, 医学系研究科, 助教 2011 – 2015: 大阪大学, 医学(系)研究科(研究院), 助教 2010: 大阪大学, 医学系研究科, 助教 2007: Osaka Univetsty, Faculty of medicine, assistant professor 2006: 大阪大学, 医学部附属病院, 医員(研究職) 2006: Osaka University Hospital, Perinatal center, Part-time Residfent, 医学部附属病院, 非常勤医員 2005: 大阪大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Embryonic/Neonatal medicine / Pediatrics Except Principal Investigator Pediatrics / Embryonic/Neonatal medicine
Keywords	Principal Investigator ダウン症候群 / iPS細胞 / ゲノム編集 / 未熟児くる病 / 新生児 / 骨代謝 / Klotho / FGF23 / FGF23 (fibroblast growth factor) / 成長障害 … More Except Principal Investigator プロスタグランジンD2 / 脱随 / 神経炎症 / ミクログリア / アストロサイト / プロスタグランジンD合成酵素 / 神経病理 / アポトーシス / 脱髄 / Demyelination / Prostaglandin D2 / Neuroinflammation / Microglia / Astrocyte / Prostaglandin D synthase / Neuropathology / Apoptois / 新生児低酸素性虚血性脳症 / 脳浮腫 / hypoxic-ischemic injury / prostaglandin D2 / brain edema Less

Generation of disease-specific iPSC library for the identification of responsible genes in Down syndromePrincipal Investigator
- Principal Investigator
  
  荒堀仁美
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University
Analysis of disease mechanism of growth impairment in Down syndrome using human iPS cellsPrincipal Investigator
- Principal Investigator
  
  ARAHORI HITOMI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Osaka University
Analysis of Rickets in the premature baby using a new biomarker, FGF23 and KlothoPrincipal Investigator
- Principal Investigator
  
  ARAHORI Hitomi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Osaka University
The effect of prostaglandin D2 in neonatal hypoxic-ischemic injury
- Principal Investigator
  
  WADA Kazuko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Osaka University
Prostaglandin D_2 is a key molecule for neuroinflammation in the demyelinating diseases
- Principal Investigator
  
  TANIIKE Masako
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University

All 2016 2014 2012 2011 2007 2006 Other

All Journal Article Presentation

[Journal Article] 1.Systematic cellular disease models reveal synergistic interactions of trisomy 21 and GATA1 mutations in hematopoietic abnormalities2016
- Author(s)
  K. Banno, S. Omori, K. Hirata, N. Nawa, N. Nakagawa, K. Nishimura, M. Ohtaka, M. Nakanishi, T. Sakuma, T. Yamamoto, T. Toki, E. Ito, T. Yamamoto, C. Kokubu, J. Takeda, H. Taniguchi, H. Arahori, K. Wada, Y. Kitabatake and K. Ozono
- Journal Title
  
  Cell Rep.
  
  Volume: 15 Pages: 1228-1241
- DOI
  10.1016/j.celrep.2016.04.031
- NAID
  120005774745
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461583, KAKENHI-PROJECT-14J04075, KAKENHI-PROJECT-24591601, KAKENHI-PROJECT-25461546, KAKENHI-PROJECT-25461643, KAKENHI-PROJECT-26253061, KAKENHI-PROJECT-15K15384, KAKENHI-PROJECT-26860799, KAKENHI-PROJECT-16K10090, KAKENHI-PROJECT-16K18478
[Journal Article] Serum Concentrations of Bevacizumab (Avastin®) and Vascular Endothelial Growth Factor in Infants with Retinopathy of Prematurity2012
- Author(s)
  Sato T, Wada K, Arahori H, Kuno N, Imoto K, Iwahashi-Shima C, Kusaka S
- Journal Title
  
  Am J Ophthalmol
  
  Volume: 153 Pages: 327-333
- DOI
  10.1016/j.ajo.2011.07.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791028, KAKENHI-PROJECT-23592597
[Journal Article] Circulating levels of soluble alpha-Klotho are markedly elevated in human umbilical cord blood2011
- Author(s)
  Yasuhisa Ohata, Hitomi Arahori, Noriyuki Namba, Taichi Kitaoka, Haruhiko Hirai, Kazuko Wada, Masahiro Nakayama, Toshimi Michigami, Akihiro Imura, Yo-ichi Nabeshima, Yuji Yamazaki, and Keiichi Ozono
- Journal Title
  
  J Clin Endocrinol Metab
  
  Volume: 96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791028
[Journal Article] Sonographic femur length to trunk cross area ratio: prediction of fetal outcome in 30 cases in which micromelia was suspected.2007
- Author(s)
  Arahori H, Tamura A, Wasada K, Shimoya K, Wada K, Murata Y, Ozono K.
- Journal Title
  
  J Obstet Gynaecol Res. 33(3)
  
  Pages: 284-53
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591218
[Journal Article] Early induction of neuronal lipocalin-type prostaglandin D synthase after hypoxic-ischemic injury in developing brains2007
- Author(s)
  Taniguchi, H, Okabe-Arahori, H, Wada, K, et. al.
- Journal Title
  
  Neurosci lett 420(1)
  
  Pages: 39-44
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591218
[Journal Article] Prostaglandin D2 protects neonatal mouse brain from hypoxic ischemic injury.2007
- Author(s)
  Taniguchi H, Mohri I, Okabe-Arahori H, Aritake K, Wada K, Kanekiyo T, Narumiya S, Nakayama M, Ozono K, Urade Y, Taniike M.
- Journal Title
  
  J Neurosci 27
  
  Pages: 4303-4312
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591085
[Journal Article] Prostaglandin D2 protects neonatal mouse brain from hypoxic ischemic injury2007
- Author(s)
  Taniguchi, H, Okabe-Arahori, H, Wada, K, et. al.
- Journal Title
  
  J Neurosci 27(16)
  
  Pages: 4308-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591218
[Journal Article] Early induction of neuronal lipocalin-type prostaglandin D synthase after hypoxic-ischemic injury in developing brains.2007
- Author(s)
  Taniguchi H, Okabe-Arahori H, Wada K, et. al.
- Journal Title
  
  Neurosci Lett. 420(1)
  
  Pages: 39-44
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591218
[Journal Article] Prostaglandin D2 protects neonatal mouse brain from hypoxic ischemic in jury.2007
- Author(s)
  Taniguchi H, Okabe-Arahori H, Wada K, et. al.
- Journal Title
  
  J Neurosci. 27(16)
  
  Pages: 4303-12
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591218
[Journal Article] Sonographic femur length to trunk cross area ratio : prediction of fetal outcome in 30 cases in which micromelia was suspected2007
- Author(s)
  Arahori, H, Tamura, A, Wasada, K, Shimoya, K, Wada, K, Murata, Y, Ozono, K
- Journal Title
  
  J Obstet Gynaecol Res 33(3)
  
  Pages: 284-53
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591218
[Journal Article] Prostaglandin D2 protects neonatal mouse brain from hypoxic ischemic injury.2007
- Author(s)
  Taniguchi H, Okabe-Arahori H, Wada K, et. al.
- Journal Title
  
  J neurosci. 27(16)
  
  Pages: 4303-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591218
[Journal Article] CMV DNA detection in dried blood spots for diagnosing congenital CMV infection in Japan.2006
- Author(s)
  Yamagishi Y, Wada K, Arahori H, Tamura A, et al.
- Journal Title
  
  J Med Virol. 78(7)
  
  Pages: 923-925
- Data Source
  KAKENHI-PROJECT-18591218
[Journal Article] Early induction of neuronal lipocalin-type prostaglandin D synthase after hypoxic-ischemic injury in developing brains.
- Author(s)
  Taniguchi H, Mohri I, Okabe-Arahori H, Kanekiyo T, Kagitani- Shimono K, Wada K, Urade Y, Nakayama M, Ozono K, Taniike M.
- Journal Title
  
  Neurosci Lett (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591085
[Journal Article] Circulating Levels of Soluble α-Klotho Are Markedly Elevated in Human Umbilical Cord Blood
- Author(s)
  Yasuhisa Ohata, Hitomi Arahori, ら
- Journal Title
  
  The Journal of Clinical Endocrinology and Metabolism
  
  Volume: (掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791028
[Presentation] 疾患特異的ヒトiPS細胞をもちいたダウン症候群の病態解析2014
- Author(s)
  北畠康司、坂野公彦、大森早也佳、平田克弥、那波伸敏、和田和子、荒堀仁美、谷口英俊、大薗恵一
- Organizer
  第37回日本小児遺伝学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2014-04-10
- Data Source
  KAKENHI-PROJECT-25461643
[Presentation] ダウン症候群における病態発症メカニズムの解明2014
- Author(s)
  北畠康司、坂野公彦、平田克弥、大森早也佳、荒堀仁美、松浪桂、谷口英俊、和田和子、大薗恵一
- Organizer
  第117回日本小児科学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2014-04-11
- Data Source
  KAKENHI-PROJECT-25461643

1. TANIIKE Masako (30263289)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. WADA Kazuko (30294094)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
3. SAKAI Norio (30314313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 田村有広 (50379187)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 北畠康司 (80506494)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 谷口英俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 伊藤悦朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 土岐力

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 平田克弥

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 佐久間哲史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 日下俊次

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ARAHORI Hitomi 荒堀 仁美

荒堀 仁美 アラホリ ヒトミ

Research Projects

Research Products

Co-Researchers

Generation of disease-specific iPSC library for the identification of responsible genes in Down syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of disease mechanism of growth impairment in Down syndrome using human iPS cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of Rickets in the premature baby using a new biomarker, FGF23 and KlothoPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of prostaglandin D2 in neonatal hypoxic-ischemic injury

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Prostaglandin D_2 is a key molecule for neuroinflammation in the demyelinating diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 1.Systematic cellular disease models reveal synergistic interactions of trisomy 21 and GATA1 mutations in hematopoietic abnormalities2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Serum Concentrations of Bevacizumab (Avastin®) and Vascular Endothelial Growth Factor in Infants with Retinopathy of Prematurity2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Circulating levels of soluble alpha-Klotho are markedly elevated in human umbilical cord blood2011

Author(s)

Journal Title

Data Source

[Journal Article] Sonographic femur length to trunk cross area ratio: prediction of fetal outcome in 30 cases in which micromelia was suspected.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Early induction of neuronal lipocalin-type prostaglandin D synthase after hypoxic-ischemic injury in developing brains2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Prostaglandin D2 protects neonatal mouse brain from hypoxic ischemic injury.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Prostaglandin D2 protects neonatal mouse brain from hypoxic ischemic injury2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Early induction of neuronal lipocalin-type prostaglandin D synthase after hypoxic-ischemic injury in developing brains.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Prostaglandin D2 protects neonatal mouse brain from hypoxic ischemic in jury.2007

Author(s)

Journal Title

Description

Data Source

ARAHORI Hitomi 荒堀仁美

荒堀仁美アラホリヒトミ