Nakamoto Nobuhiro 中本伸宏

… Alternative Names

Researcher Number	40383749
Other IDs
Affiliation (Current)	2019: 慶應義塾大学, 医学部(信濃町), 講師
Affiliation (based on the past Project Information) *help	2016 – 2017: 慶應義塾大学, 医学部(信濃町), 講師 2015: 慶應義塾大学, 医学部(信濃町), 専任講師 2014 – 2015: 慶應義塾大学, 医学部, 講師 2010 – 2013: 慶應義塾大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Gastroenterology Except Principal Investigator Gastroenterology
Keywords	Principal Investigator 免疫学 / 腸内細菌 / 急性肝障害 / マクロファージ / 免疫寛容 / トランスレーショナルリサーチ / 原発性硬化性胆管炎 / 肝臓学 / 肝線維化 / 腸肝相関 … More Except Principal Investigator 免疫寛容 / T細胞疲弊 / NKT細胞 / 獲得免疫 / C型肝炎ウイルス / 腸肝相関 / CD8 T細胞 / NK細胞 / HCV特異的T細胞 / CD8T細胞 / T細胞の疲弊 / C型肝炎 / C型慢性肝炎 / exhaustion Less

腸肝指向性腸内細菌と肝臓内免疫応答を介した原発性硬化性胆管炎の進展機序の解明Principal InvestigatorOngoing
- Principal Investigator
  
  中本伸宏
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
The interaction between the intestinal microbiota and hepatic macrophages in the pathogenesis of liver fibrosisPrincipal Investigator
- Principal Investigator
  
  Nakamoto Nobuhiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Comprehensive analysis of dysfunctional HCV specific CD8 T cell during persistent HCV infection
- Principal Investigator
  
  Ishibashi Yuka
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Pathogenesis of autoimmune hepatic injury through the migration of immunocompetent cells into the liverPrincipal Investigator
- Principal Investigator
  
  NAKAMOTO Nobuhiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University

All 2017 2016 2015 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Does the Intestinal Microbiota Explain Differences in the Epidemiology of Liver Disease between East and West?2016
- Author(s)
  Nobuhiro Nakamoto and Bernd Schnabl
- Journal Title
  
  Inflammatory Intestinal Diseases
  
  Volume: 1 Pages: 3-8
- DOI
  10.1159/000443196
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860559
[Journal Article] CCR9(+) plasmacytoid dendritic cells in the small intestine suppress development of intestinal inflammation in mice.2012
- Author(s)
  Mizuno S, Kanai T, Mikami Y, Sujino T, Ono Y, Hayashi A, Handa T,Matsumoto A, Nakamoto N, Matsuoka K, Hisamatsu T, Takaishi H, Hibi T.
- Journal Title
  
  Immunol Lett
  
  Volume: 146 Pages: 64-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590744
[Journal Article] CCR9+ macrophages are required for acute liver inflammation in mouse models of hepatitis.2012
- Author(s)
  Nakamoto N, Ebinuma H, Kanai T, Chu PS, Ono Y, Mikami Y, Ojiro K, Lipp M, Love PE, Saito H, Hibi T.
- Journal Title
  
  Gastroenterology
  
  Volume: 142 Pages: 366-376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590744
[Presentation] 原発性硬化性胆管炎の病態における腸内細菌の関与2017
- Author(s)
  中本伸宏
- Organizer
  日本消化器病学会大会
- Data Source
  KAKENHI-PROJECT-16K09374
[Presentation] Collaboration of intestinal microbiota induces bacterial translocation and Th17 immune response in primary sclerosing cholangitis2017
- Author(s)
  中本伸宏
- Organizer
  米国肝臓学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09374
[Presentation] The gut-liver axis plays a crucial role in murine immune tolerance in the liver2016
- Author(s)
  中本伸宏
- Organizer
  The Ameriac association for immunologists 2016 annual meeting
- Place of Presentation
  Seattle, USA
- Year and Date
  2016-05-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09374
[Presentation] The gut-liver axis plays a crucial role in murine immune tolerance in the liver2015
- Author(s)
  Nobuhiro Nakamoto
- Organizer
  AASLD 2015 annual meeting
- Place of Presentation
  San Francisco, USA
- Year and Date
  2015-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860559
[Presentation] マウスCon A急性肝不全モデルでの病因性CCR9陽性マクロファージの発見から、肝臓各病態形成への関与2013
- Author(s)
  中本伸宏
- Organizer
  日本消化器病学会総会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-22590744
[Presentation] ケモカイン・ケモカイン受容体ＣＣＬ２５／ＣＣＲ９を介する肝線維化促進機序：マウス肝線維化モデルでの検討2013
- Author(s)
  楮柏松、中本伸宏
- Organizer
  第50回日本消化器免疫学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25860559
[Presentation] Newly identified TNF-α-producing CCR9^+ macrophages induce acute liver inflammation in mice2011
- Author(s)
  Nobuhiro Nakamoto, et.al.
- Organizer
  62^<nd> Annual Meeting of the AASLD
- Place of Presentation
  San Francisco, USA
- Year and Date
  2011-11-08
- Data Source
  KAKENHI-PROJECT-22590744
[Presentation] Newly identified TNF-α-producing CCR9+ macrophages induce acute liver inflammation in mice2011
- Author(s)
  Nobuhiro Nakamoto et.al
- Organizer
  62nd Annual Meeting of the AASLD
- Place of Presentation
  San Francisco,USA
- Year and Date
  2011-11-08
- Data Source
  KAKENHI-PROJECT-22590744
[Presentation] 自己免疫応答性急性肝障害の病態形成におけるCCR9 陽性マクロファージの役割2011
- Author(s)
  中本伸宏
- Organizer
  第97回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-22590744
[Presentation] マウスPlasmacytoid DCの肝臓免疫寛容への関与2010
- Author(s)
  中本伸宏
- Organizer
  第38回日本肝臓学会東部会
- Place of Presentation
  東京
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-22590744
[Presentation] マウス肝臓内免疫担当細胞の免疫寛容への関与2010
- Author(s)
  中本伸宏
- Organizer
  第38回日本肝臓学会東部会
- Place of Presentation
  東京・京王プラザホテル
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-22590744
[Presentation] A distinct role for the TLR9 pathway in immune activation and tolerance during acute liver injury in mice
- Author(s)
  中本伸宏
- Organizer
  米国肝臓学会
- Place of Presentation
  Boston, USA
- Year and Date
  2014-11-09 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-25860559
[Presentation] C型慢性肝炎難治例における抗ウイルス療法中の末梢血HCV特異的CD8 T細胞機能の経時的変化と補助シグナル阻害による機能修飾の検討
- Author(s)
  中本伸宏
- Organizer
  第17回日本肝臓学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790720

1. KANAI Takanori (40245478)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. Ishibashi Yuka (60528305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 須田亙 (20590847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 福田真嗣 (80435677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Nakamoto Nobuhiro 中本 伸宏

NAKAMOTO Nobuhiro 中本 伸宏

Research Projects

Research Products

Co-Researchers

腸肝指向性腸内細菌と肝臓内免疫応答を介した原発性硬化性胆管炎の進展機序の解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The interaction between the intestinal microbiota and hepatic macrophages in the pathogenesis of liver fibrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive analysis of dysfunctional HCV specific CD8 T cell during persistent HCV infection

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathogenesis of autoimmune hepatic injury through the migration of immunocompetent cells into the liverPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Does the Intestinal Microbiota Explain Differences in the Epidemiology of Liver Disease between East and West?2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CCR9(+) plasmacytoid dendritic cells in the small intestine suppress development of intestinal inflammation in mice.2012

Author(s)

Journal Title

Data Source

[Journal Article] CCR9+ macrophages are required for acute liver inflammation in mouse models of hepatitis.2012

Author(s)

Journal Title

Data Source

[Presentation] 原発性硬化性胆管炎の病態における腸内細菌の関与2017

Author(s)

Organizer

Data Source

[Presentation] Collaboration of intestinal microbiota induces bacterial translocation and Th17 immune response in primary sclerosing cholangitis2017

Author(s)

Organizer

Data Source

[Presentation] The gut-liver axis plays a crucial role in murine immune tolerance in the liver2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] The gut-liver axis plays a crucial role in murine immune tolerance in the liver2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] マウスCon A急性肝不全モデルでの病因性CCR9陽性マクロファージの発見から、肝臓各病態形成への関与2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] ケモカイン・ケモカイン受容体ＣＣＬ２５／ＣＣＲ９を介する肝線維化促進機序：マウス肝線維化モデルでの検討2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Newly identified TNF-α-producing CCR9^+ macrophages induce acute liver inflammation in mice2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Newly identified TNF-α-producing CCR9+ macrophages induce acute liver inflammation in mice2011

Author(s)

Nakamoto Nobuhiro 中本伸宏

NAKAMOTO Nobuhiro 中本伸宏