Yamaoka Toshimitsu 山岡利光

… Alternative Names

山岡利光ヤマオカトシミツ

YAMAOKA Toshimitsu 山岡利光

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Researcher Number	40384359
Other IDs
Affiliation (Current)	2025: 昭和大学, 大学共同利用機関等の部局等, 准教授
Affiliation (based on the past Project Information) *help	2023: 昭和大学, 大学共同利用機関等の部局等, 准教授 2018: 昭和大学, 先端がん治療研究所, 准教授 2018: 昭和大学, 大学共同利用機関等の部局等, 准教授 2017: 昭和大学, 腫瘍分子生物学研究所, 准教授 2011 – 2016: 昭和大学, 腫瘍分子生物学研究所, 講師 … More 2013: 昭和大学, 腫場分子生物学研究所, 講師 2012: 昭和大学, 医学部, 講師 2012: 昭和大学, 大学共同利用機関等の部局等, 講師 2009 – 2011: Showa University, 医学部, 助教 Less
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Tumor biology Except Principal Investigator Basic Section 90130:Medical systems-related / Applied pharmacology / General pharmacology / Clinical oncology
Keywords	Principal Investigator 腫瘍壊死因子 / 上皮成長因子受容体 / EGFR / 肺障害 / 肺癌 / 慢性閉塞性肺疾患 / COPD / 発癌 / TNF / ヒト上皮成長因子受容体 … More / 上皮成長因子受容体阻害剤 / 肺線維症 / アポトーシス / TACE / apoptosis / TNF-alpha / 急性肺障害 … More Except Principal Investigator 薬剤耐性 / EGFR / 非小細胞性肺癌 / リキッドバイオプシー / 末梢血循環癌細胞 / ファーマコゲノミクス / FADD / MET / c-MET / EGFR阻害剤 / crosstalk signal / EGFR-TKI / TRAIL / 扁平上皮癌 / 肺癌 / ADAM17 / 上皮成長因子受容体 / 喫煙 / 肺扁平上皮癌 / 扁平上皮肺癌 / 喫煙者肺癌 Less

Development of the new technique for capturing circulating tumor cells of non-small cell lung cancer.
- Principal Investigator
  
  長谷部友紀
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Showa University
Investigate the role of TNF and EGFR in the onset and progression of lung cancer complicated with COPDPrincipal Investigator
- Principal Investigator
  
  Yamaoka Toshimitsu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Showa University
The potential mechanisms of EGFR-TKI induced lung injury in mice modelPrincipal Investigator
- Principal Investigator
  
  Yamaoka Toshimitsu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Showa University
Elucidation of trans-activation mechanism from TRAIL receptor to EGFR
- Principal Investigator
  
  OHMORI Tohru
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Showa University
Association of pharmacokinetics or pharmacogenomics with toxicity of erlotinib in patients with advanced non-small cell lung cancer
- Principal Investigator
  
  HIROSE Takashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Tokyo National Hospital (Clinical research)
  Showa University
The role of ADAM17 in squamous cell lung cancer
- Principal Investigator
  
  SIRAI Takao
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical oncology
- Research Institution
  Showa University
TNF induced lung injury was protected by EGFR transactivationPrincipal Investigator
- Principal Investigator
  
  YAMAOKA Toshimitsu
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Showa University

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] EGFR阻害剤の耐性とその克服(The mechanisms of resistance to EGFR-TKIs and challenges to overcome resistance in EGFR mutant Non-small cell lung cancer)(39巻6号)2012
- Author(s)
  山岡利光, 大森亨
- Publisher
  癌と化学療法
- Data Source
  KAKENHI-PROJECT-23590308
[Book] 癌と化学療法2012
- Author(s)
  山岡利光
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-21790788
[Book] 癌と化学療法2012
- Author(s)
  山岡利光
- Total Pages
  6
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-22501051
[Journal Article] KRAS and EGFR Amplifications Mediate Resistance to Rociletinib and Osimertinib in Acquired Afatinib-Resistant NSCLC Harboring Exon 19 Deletion/T790M in EGFR2018
- Author(s)
  Nakatani Kaori、Yamaoka Toshimitsu、Ohba Motoi、Fujita Ken-Ichi、Arata Satoru、Kusumoto Sojiro、Taki-Takemoto Iori、Kamei Daisuke、Iwai Shinichi、Tsurutani Junji、Ohmori Tohru
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 18 Issue: 1 Pages: 112-126
- DOI
  10.1158/1535-7163.mct-18-0591
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08413, KAKENHI-PROJECT-16K09590, KAKENHI-PROJECT-17K07226
[Journal Article] Receptor Tyrosine Kinase-Targeted Cancer Therapy2018
- Author(s)
  Yamaoka Toshimitsu、Kusumoto Sojiro、Ando Koichi、Ohba Motoi、Ohmori Tohru
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 11 Pages: 3491-3491
- DOI
  10.3390/ijms19113491
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09590, KAKENHI-PROJECT-17K07226
[Journal Article] Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure.2017
- Author(s)
  Yamaoka T, Ohba M, Arata S, Ohmori T.
- Journal Title
  
  J Vis Exp
  
  Volume: 126 Issue: 126 Pages: 1-10
- DOI
  10.3791/55967
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09590, KAKENHI-PROJECT-17K07226
[Journal Article] Distinct Afatinib Resistance Mechanisms Identified in Lung Adenocarcinoma Harboring an EGFR Mutation.2017
- Author(s)
  Yamaoka T, Ohmori T, Ohba M, Arata S, Murata Y, Kusumoto S, Ando K, Ishida H, Ohnishi T, Sasaki Y.
- Journal Title
  
  Mol Cancer Res.
  
  Volume: 7 Pages: 915-928
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09590
[Journal Article] Molecular-Targeted Therapies for Epidermal Growth Factor Receptor and Its Resistance Mechanisms.2017
- Author(s)
  Yamaoka T, Ohba M, Ohmori T.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 18 Issue: 11 Pages: 2420-2442
- DOI
  10.3390/ijms18112420
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09590, KAKENHI-PROJECT-17K07226
[Journal Article] The acquired resistant mechanisms for sequential treatment of EGFR-TKI to Met-TKI/EGFR-TKI in a Met amplified EGFR-TKI resistant lung adenocarcinoma cells, harboring EGFR activating mutation.2016
- Author(s)
  64.Yamaoka T., Ohmori T., Ohba M., Arata S., Kishino Y., Murata Y., Kusumoto S., Ishida H., Shirai T., Hirose T., Ohnishi T., and Sasaki Y.
- Journal Title
  
  Mol. Cancer Ther.
  
  Volume: 15 Issue: 12 Pages: 3040-3054
- DOI
  10.1158/1535-7163.mct-16-0313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460153, KAKENHI-PROJECT-16K09590
[Journal Article] Association of pharmacokinetics and pharmacogenomics with safety and efficacy of gefitinib in patients with EGFR mutation positive advanced non-small cell lung cancer2016
- Author(s)
  廣瀬敬、藤田健一、楠本壮二郎、大木康成、村田泰規、杉山智秀、石田博雄、白井崇生、中嶌賢尚、山岡利光、奥田健太郎、大森亨、佐々木康綱
- Journal Title
  
  Lung Cancer
  
  Volume: 93 Pages: 69-76
- DOI
  10.1016/j.lungcan.2016.01.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25870736
[Journal Article] Up-regulation of Syndecan-4 contributes to TGF-β1-induced epithelial to mesenchymal transition in lung adenocarcinoma A549 cells2016
- Author(s)
  市橋陽子、山岡利光、大森亨、大場基
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 5 Pages: 1-7
- DOI
  10.1016/j.bbrep.2015.11.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25870736, KAKENHI-PROJECT-25460153
[Journal Article] Phase 2 study of concurrent chemoradiotherapy with carboplatin and vinorelbin for locally advanced non-small-cell lung cancerr2014
- Author(s)
  Ishida, K, Kagami, Y. et al.
- Journal Title
  
  Molecular and clinical oncology
  
  Volume: 18(1) Issue: 3 Pages: 41-53
- DOI
  10.3892/mco.2014.252
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591851, KAKENHI-PROJECT-25870736
[Journal Article] EGFR阻害剤の耐性とその克服 (The mechanisms of resistance to EGFR-TKIs and challenges to overcome resistance in EGFR mutant Non-small cell lung cancer)2012
- Author(s)
  山岡利光, 大森　亨
- Journal Title
  
  癌と化学療法
  
  Volume: 39 Pages: 857-862
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] 進行再発非小細胞肺癌に対するセカンドライン化学療法の検討2012
- Author(s)
  白井崇生, 慶瀬敬, 村田泰規, 大木康成, 楠本壮三郎, 杉山智英, 石田博雄, 中属賢尚, 大西司, 山岡利光, 大森亨, 奥田健太郎
- Journal Title
  
  昭和医学会雑誌
  
  Volume: 72巻4号 Pages: 446-452
- NAID
  130003378205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501051
[Journal Article] EGFR阻害剤の耐性とその克服 (The mechanisms of resistance to EGFR-TKIs and challenges to overcome resistance in EGFR mutant Non-small cell lung cancer)2012
- Author(s)
  山岡利光, 大森亨
- Journal Title
  
  癌と化学療法
  
  Volume: 39巻6号 Pages: 857-862
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790788
[Journal Article] Relationship of circulating tumor cells to the effectiveness of cytotoxic chemotherapy in patients with metastatic non-small-cell lung cancer.2012
- Author(s)
  Hirose T, Murata Y, Oki Y, Sugiyama T, Kusumoto S, Ishida H, Shirai T, Nakashima M, Yamaoka T, Okuda K, Ohnishi T, Ohmori T.
- Journal Title
  
  Oncology Research
  
  Volume: 20 Pages: 131-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] Relationship of circulating tumor cells to the effectiveness of cytotoxic chemotherapy in patients with metastatic non-small-cell lung cancer2012
- Author(s)
  Hirose T, Yamaoka T, Ohmori T. et al
- Journal Title
  
  Oncol Res
  
  Volume: 20(2-3) Pages: 131-137
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] Evaluation of the safety and efficacy of combination chemotherapy with vinorelbine and platinum agents for patients with non-small cell lung cancer with interstitial lung disease2012
- Author(s)
  Okuda K, Hirose T, Yamaoka T, Ohmori T. et al
- Journal Title
  
  Anticancer Res
  
  Volume: 32(2) Pages: 5475-5480
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] Evaluation of the safety and efficacy of combination chemotherapy with vinorelbine and platinum agents for patients with non-small cell lung cancer with interstitial lung disease2012
- Author(s)
  Okuda K, Hirose T, Oki Y, Murata Y, Kusumoto S, Sugiyama T, Ishida H, Shirai T, Nakashima M, Yamaoka T, Ohnishi T, Ohmori T
- Journal Title
  
  Anticancer Res.
  
  Volume: 32(12) Pages: 5475-80
- URL
  http://ar.iiarjournals.org/content/32/12/5475.long
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501051
[Journal Article] Relationship of circulating tumor cells to the effectiveness of cytotoxic chemotherapy in patients with metastatic non-small-cell lung cancer2012
- Author(s)
  Hirose T, Murata Y, Oki Y, Sugiyama T, Kusumoto S, Ishida H, Shirai T, Nakashima M, Yamaoka T, Okuda K, Ohnishi T, Ohmori T
- Journal Title
  
  Oncol Res.
  
  Volume: 20(2-3) Pages: 131-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501051
[Journal Article] Evaluation of the safety and efficacy of combination chemotherapy with vinorelbine and platinum agents for patients with non-small cell lung cancer with interstitial lung disease.2012
- Author(s)
  Okuda K, Hirose T, Oki Y, Murata Y, Kusumoto S, Sugiyama T, Ishida H, Shirai T, Nakashima M, Yamaoka T, Ohnishi T, Ohmori T.
- Journal Title
  
  Anticancer Researcg
  
  Volume: 32 Pages: 1337-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] Specific epidermal growth factor receptor autophosphorylation sites promote mouse colon epithelial cell chemotaxis and restitution2011
- Author(s)
  山岡利光
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 301 Pages: 368-376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790788
[Journal Article] Myelosuppression induced by concurrent chemoradiotherapy as a prognostic factor for patients with locally advanced non-small cell lung cancer2011
- Author(s)
  Kishida Y, Hirose T, Shirai T, Sugiyama T, Kusumoto S, Yamaoka T, Okuda K, Adachi M, Nakamura A
- Journal Title
  
  Oncol Lett.
  
  Volume: 2(5) Pages: 949-955
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501051
[Journal Article] Specific epidermal growth factor receptor autophosphorylation sites promote mouse colon epithelial cell chemotaxis and restitution2011
- Author(s)
  Yamaoka T, Frey MR, Dise RS, Bernard JK, Polk DB
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 301(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790788
[Journal Article] Phase II trial of amrubicin and carboplatin in patients with sensitive or refractory relapsed small-cell lung cancer2011
- Author(s)
  Hirose T, Yamaoka T, Ohmori T, et al
- Journal Title
  
  Lung Cancer
  
  Volume: (Epub ahead of print)
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] Phase II trial of amrubicin and carboplatin in patients with sensitive or refractory relapsed small -cell lung cancer2011
- Author(s)
  Hirose T, Nakashima M, Shirai T, Kusumoto S, Sugiyama T, Yamaoka T, Okuda K, Ohnishi T, Ohmori T, Adachi M
- Journal Title
  
  Lung Cancer
  
  Volume: 73(3) Issue: 3 Pages: 345-50
- DOI
  10.1016/j.lungcan.2010.12.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501051
[Journal Article] Phase II study of S-1, a novel oral fluoropyrimidine, and biweekly administration of docetaxel for previously treated advanced non-small-cell lung cancer2011
- Author(s)
  Oki Y, Hirose T, Yamaoka T, Ohmori T, et al
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 67(4) Pages: 791-797
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] Phase II trial of the combination of carboplatin and irinotecan in elderly patients with small -cell lung cancer2011
- Author(s)
  Murata Y, Hirose T, Yamaoka T, Shirai T, Okuda K, Sugiyama T, Kusumoto S, Nakashima M, Ohmori T, Adachi M
- Journal Title
  
  Eur J Cancer
  
  Volume: 47(9) Issue: 9 Pages: 1336-42
- DOI
  10.1016/j.ejca.2011.03.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501051
[Journal Article] Phase II trial of the combination of carboplatin and irinotecan in elderly patients with small-cell lung cancer2011
- Author(s)
  Murata Y, Hirose T, Yamaoka T, Ohmori T, et al
- Journal Title
  
  Eur J Cancer
  
  Volume: 47(9) Pages: 1336-1342
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] Are levels of pro-gastrin-releasing peptide or neuron-specific enolase at relapse prognostic factors after relapse in patients with small -cell lung cancer?2011
- Author(s)
  Hirose T, Okuda K, Yamaoka T, Ishida K, Kusumoto S, Sugiyama T, Shirai T, Ohnshi T, Ohmori T, Adachi M
- Journal Title
  
  Lung Cancer
  
  Volume: 71(2) Issue: 2 Pages: 224-8
- DOI
  10.1016/j.lungcan.2010.05.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501051
[Journal Article] Are levels of pro-gastrin-releasing peptide or neuron-specific enolase at relapse prognostic factors after relapse in patients with small-cell lung cancer?2011
- Author(s)
  Hirose T, Yamaoka T, Ohmori T, et al
- Journal Title
  
  Lung Cancer
  
  Volume: 71(2) Pages: 224-228
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] Phase II study of S-1,a novel oral fluoropyrimidine,and biweekly administration of docetaxel for previously treated advanced non-small-cell lung cancer2011
- Author(s)
  Oki Y, Hirose T, Yamaoka T, Kusumoto S, Shirai T, Sugiyama T, Okuda K, Nakashima M, Murata Y, Ohmori T, Adachi M
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 67(4) Issue: 4 Pages: 791-7
- DOI
  10.1007/s00280-010-1382-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501051
[Journal Article] Evaluation of the efficacy and safety of the combination of gemcitabine and nedaplatin for elderly patients with advanced non-small-cell lung cancer2011
- Author(s)
  Sugiyama T, Hirose T, Yamaoka T, Ohmori T, et al
- Journal Title
  
  Oncology
  
  Volume: 81(3-4) Pages: 273-280
- Data Source
  KAKENHI-PROJECT-23590308
[Journal Article] The UGT1A1*28 genotype and the toxicity of low -dose irinotecan in patients with advanced lung cancer2010
- Author(s)
  Sugiyama T, Hirose T, Kusumoto S, Shirai T, Yamaoka T, Okuda K, Ohnishi T, Ohmori T, Adachi M
- Journal Title
  
  Oncol Res.
  
  Volume: 18(7) Pages: 337-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] KRAS amplification mediates resistance to osimertinib in acquired afatinib-resistant NSCLC harboring exon 19 deletion/T790M in EGFR2019
- Author(s)
  Toshimitsu Yamaoka, Motoi Ohba, Yasunari Kishino, Sojiro Kusumoto, Junji Tsurutani, Tohru Ohmori
- Organizer
  AACR 110th Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09590
[Presentation] GFR遺伝子変異陽性(exon19del/T790M)肺腺癌細胞株におけるオシメルチニブ獲得耐性機序2019
- Author(s)
  山岡利光, 岸野康成, 楠本壮二郎, 鶴谷純司, 相良博典, 大森亨
- Organizer
  第59回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-16K09590
[Presentation] T790M-EGFRによりアファチニブ耐性をきたした肺腺癌細胞株におけるロシレチニブ耐性機序の検討2018
- Author(s)
  山岡利光,楠本壮二郎,安藤浩一,石田博雄,大西司,相良博典,大森亨
- Organizer
  第59回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09590
[Presentation] EGFR-T790Mを発現した肺腺癌細胞における第３世代EGFR-TKI,ロシレチニブの獲得耐性機序の検討2018
- Author(s)
  山岡利光,中谷香織, 大場基, 藤田健一, 岩井信市, 大森亨
- Organizer
  第76回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-16K09590
[Presentation] 次元培養法を用いたキナーゼ阻害剤の感受性評価.2018
- Author(s)
  伊東里紗, 鈴木俊宏, 山岡利光, 大森亨, 西尾和人, 小笠原裕樹
- Organizer
  第76回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-16K09590
[Presentation] EGFR-Mutationを伴う肺腺癌細胞株におけるEGFR-TKIとMET-TKIへの獲得耐性機序2017
- Author(s)
  山岡利光　大森亨　大場基　村田泰規　大木康成　楠本壮二郎　大西司　相良博典
- Organizer
  第57回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-16K09590
[Presentation] Distinct Afatinib Resistance Mechanisms Identified in Lung Adenocarcinoma Harboring an EGFR Mutation2017
- Author(s)
  山岡利光　大場基　荒田悟　大森亨
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K09590
[Presentation] EGFR遺伝子変異を有する肺腺癌細胞株PC-9におけるafatinib獲得耐性機序の検討2017
- Author(s)
  山岡利光　大場基　荒田悟　大森亨
- Organizer
  第58回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09590
[Presentation] EGFR-Mutationを伴う肺腺癌細胞株におけるEGFR-TKIとMET-TKIへの獲得耐性機序2016
- Author(s)
  山岡利光, 大森亨, 大場基, 村田泰規, 楠本壮二郎, 石田博雄, 佐々木康綱
- Organizer
  日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-16K09590
[Presentation] Mechanism underlying acquisition of dual resistance to EGFR and MET inhibitors by EGFR-mutant lung adenocarcinoma cells2016
- Author(s)
  Yamaoka T, Ohmori T, Ohba M, Kishino Y, Murata Y, Kusumoto S, Ishida H, Ohnishi T, Sasaki Y.
- Organizer
  AACR
- Place of Presentation
  ニューオリンズ・米国
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09590
[Presentation] Mechanism underlying acquisition of dual resistance to EGFR and MET inhibitors by EGFR-mutant lung adenocarcinoma cells2016
- Author(s)
  山岡利光, 大森亨, 大場基, 村田泰規, 楠本壮二郎, 石田博雄, 佐々木康綱
- Organizer
  臨床腫瘍学会
- Place of Presentation
  神戸
- Year and Date
  2016-07-28
- Data Source
  KAKENHI-PROJECT-16K09590
[Presentation] EGFR-Mutationを伴う肺腺癌細胞株におけるEGFR-TKIとMET-TKIへの獲得耐性機序の検討2015
- Author(s)
  山岡利光, 大森亨, 大木康成, 村田泰規, 楠本壮二郎, 石田博雄, 白井崇生, 廣瀬敬, 大西司, 佐々木康綱
- Organizer
  日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25870736
[Presentation] 肺癌患者におけるCOPDの有無による合併症・併存症の比較検討2015
- Author(s)
  岸野康成, 村田泰規, 楠本壮二郎, 石田博雄, 白井崇生, 濱田和幸, 山岡利光, 片岡大輔, 山本滋, 大西司, 大森亨, 佐々木康綱, 門倉光隆, 相良博典
- Organizer
  日本肺癌学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2015-11-26
- Data Source
  KAKENHI-PROJECT-25870736
[Presentation] 進行非小細胞肺癌におけるEGFR-TKIによる薬剤性肺障害と薬物動態および薬理遺伝子多型の関連性の検討2015
- Author(s)
  廣瀬敬, 藤田健一, 大木康成, 村田泰則, 楠本壮二郎, 杉山智英, 石田博雄, 白井崇生, 中嶌賢尚, 山岡利光, 奥田健太郎, 大森亨, 佐々木康綱, 田村厚久, 大田健
- Organizer
  日本肺癌学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2015-11-26
- Data Source
  KAKENHI-PROJECT-25870736
[Presentation] 悪性腫瘍による気道狭窄で窒息し放射線照射により救命しえた1例2015
- Author(s)
  村田泰規, 岸野康成, 楠本壮二郎, 石田博雄, 白井崇生, 山岡利光, 大西司, 大森亨, 相良博典
- Organizer
  日本肺癌学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2015-11-26
- Data Source
  KAKENHI-PROJECT-25870736
[Presentation] Contribution of miR-205 in gefitinib-resistant lung cancer cell lines2014
- Author(s)
  Toshihiro Suzuki, Toshimitsu Yamaoka, Tohru Ohmori, et al
- Organizer
  Annual Meeting 2014
- Place of Presentation
  American Association for Cancer Research SanDiego
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] TNF transactivation of EGFR protects EGFR-TKI, gefitinib induced pulmonary epithelial cell apoptosis and injury in TNF transgenic mice2014
- Author(s)
  Toshimitsu Yamaoka, Tohru Ohmori, et al
- Organizer
  Annual Meeting 2014
- Place of Presentation
  American Association for Cancer Research SanDiego(#2277)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] Tivantinib shows a synergistic growth-inhibitory effect with erlotinib through enhanced degradation of c-MET protein2014
- Author(s)
  大森　亨、山岡利光　他
- Organizer
  第12回日本臨床腫瘍学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] TNF transactivation of EGFR protects EGFR-TKI, gefitinib induced pulmonary epithelial cell apoptosis and injury in TNF transgenic mice.2014
- Author(s)
  Yamaoka T, Ohmori T et al
- Organizer
  Annual Meeting 2014, American Association for Cancer Research
- Place of Presentation
  SanDiego, CA
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] A novel c-MET inhibitor, tivantinib, shows an additive growth-inhibitory effect with erlotinib through enhanced degradation of c-MET protein via its recycling pathway2013
- Author(s)
  Tohru Ohmori, Toshimitsu Yamaoka, Takashi Hirose, et al
- Organizer
  19^<th> International Charles Heidelberger Symposium on Cancer Research
- Place of Presentation
  鹿児島(P-04)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] MET高感受性を示すEGFR-TKI耐性PC-9細胞におけるMET阻害剤耐性細胞株の樹立/The characteristics of dual resistance to EGFR & MET inhibitors in pulmonary adenocarcinoma, PC-9 cells2013
- Author(s)
  山岡利光, 大森亨, 他
- Organizer
  PC-9 cells第72回日本癌学会学術総会
- Place of Presentation
  横浜(E-2030)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] Clinical benefit of 2nd EGFR-TKI retreatment on overall survival in patients with advanced non-small cell lung cancer2013
- Author(s)
  Masanao Nakashima, Takashi Hirose, Toshimitsu Yamaoka, Tohru Ohmori, et al
- Organizer
  第11回日本臨床腫瘍学会学術集会
- Place of Presentation
  仙台(P-1413)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] The characteristics of an acquired dual resistance to EGFR & MET inhibitors in non-small cell lung cancer, harboring active mutation of EGFR.2013
- Author(s)
  Yamaoka T, Ohmori T et al
- Organizer
  Annual Meeting 2013, American Association for Cancer Research
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 非小細胞肺癌におけるエルロチニブとゾレドロン酸併用療法の有用性に関する後方視的解析2013
- Author(s)
  大木康成, 廣瀬敬, 白井崇生, 村田泰規, 杉山智英, 楠本壮二郎, 石田博雄, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 相良博典
- Organizer
  肺癌学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] 非小細胞肺癌におけるエルロチニブとゾレドロン酸併用療法の有用性に関する後方視的解析2013
- Author(s)
  大木康成, 廣瀬敬, 白井崇生, 村田泰規, 杉山智英, 楠本壮二郎, 石田博雄, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 相良博典
- Organizer
  日本肺癌学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25870736
[Presentation] The Characteristics of an acquired dual resistance to EGFR & MET inhibitors in non-small cell lung cancer, harbouring active mutation of EGFR2013
- Author(s)
  山岡利光, 市橋陽子, 村田泰規, 大木康成, 杉山智英, 石田博雄, 白井崇生, 廣瀬敬,中嶌賢尚, 奥田健太郎, 大西司, 大森亨
- Organizer
  米国癌学会 (AACR)
- Place of Presentation
  ワシントンDC
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] The characteristics of an acquired dual resistance to EGFR & MET inhibitors in non-small cell lung cancer, harboring active mutation of EGFR2013
- Author(s)
  Toshimitsu Yamaoka, Takashi Hirose, Tohru Ohmori et al
- Organizer
  #5648Annual Meeting 2013
- Place of Presentation
  American Association for Cancer Research Washington
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 非小細胞肺癌におけるエルロチニプとゾレドロン酸併用療法の有用性に関する後方視的解析2013
- Author(s)
  大木康成, 慶瀬敬, 白井崇生, 村田泰規, 杉山智英, 楠本壮三郎, 石田博雄, 中属賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 相良博典
- Organizer
  日本肺癌学会
- Place of Presentation
  東京
- Year and Date
  2013-11-21
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] 小細胞肺癌患者における末梢血中がん細胞数と予後の検討2013
- Author(s)
  白井崇生, 慶瀬敬, 村田泰規, 大木康成, 楠本壮三郎, 杉山智英, 石田博雄, 中属賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 相良博典
- Organizer
  日本肺癌学会
- Place of Presentation
  東京
- Year and Date
  2013-11-21
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] The Characteristics of dual resistance to EGFR & MET inhibitors in pulmonary adenocarcinoma, PC-9 cells2013
- Author(s)
  山岡利光, 杉山智英, 石田博雄, 白井崇生, 奥田健太郎, 外谷衣都子, 大場基, 大森亨, 佐々木康綱
- Organizer
  日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] The characteristics of dual resistance to EGFR & MET inhibitors in pulmonary adenocarcinoma, PC-9 cells2013
- Author(s)
  山岡利光, 杉山智英, 石田博雄, 白井崇生, 奥田健太郎, 外谷衣都子, 大場基, 大森亨, 佐々木康綱
- Organizer
  日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25870736
[Presentation] 脳転移を伴うEML4-ALK融合遺伝子陽性非小細胞肺癌に対しクリゾチニブを投与した2症例の検討2013
- Author(s)
  石田博雄, 村田泰規, 大木康成, 石田孔子, 白井崇生, 山岡利光, 大西司, 大森亨, 相良博典, 佐々木康綱
- Organizer
  日本肺癌学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25870736
[Presentation] MET高感受性を示すEGFR-TKI耐性PC-9細胞におけるMET阻害剤耐性細胞株の樹立／The characteristics of dual resistance to EGFR & MET inhibitors in pulmonary adenocarcinoma, PC-9 cells2013
- Author(s)
  山岡利光、大森　亨　他
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] The characteristics of an acquired dual resistance to EGFR & MET inhibitors in non-small cell lung cancer, harboring active mutation of EGFR2013
- Author(s)
  山岡利光, 市橋陽子, 大木康成, 村田泰規, 杉山智英, 石田博雄, 白井崇生, 中嶌賢尚, 奥田健太郎, 大西司, 廣瀬敬, 大森亨
- Organizer
  米国癌学会（AACR）
- Place of Presentation
  ワシントンDC
- Data Source
  KAKENHI-PROJECT-25870736
[Presentation] 小細胞肺癌患者における末梢血中がん細胞数と予後の検討2013
- Author(s)
  白井崇生, 廣瀬敬, 村田泰規, 大木康成, 楠本壮二郎, 杉山智英, 石田博雄, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 相良博典
- Organizer
  日本肺癌学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25870736
[Presentation] 小細胞肺癌患者における末梢血中がん細胞数と予後の検討2013
- Author(s)
  白井崇生, 廣瀬敬, 村田泰規, 大木康成, 楠本壮二郎, 杉山智英, 石田博雄, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 相良博典
- Organizer
  肺癌学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] 脳転移を伴うEML4-ALK融合遺伝子陽性非小細胞肺癌に対しクリゾチニブを投与した2症例の検討2013
- Author(s)
  石田博雄, 村田泰規, 大木康成, 石田孔子, 白井崇生, 山岡利光, 大西司, 大森亨, 相良博典, 佐々木康綱
- Organizer
  肺癌学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] EGFR遺伝子変異陽性肺腺癌患者に対するゲフィチニブとゾレドロン酸併用療法の有用性に関する後方視的解析2012
- Author(s)
  大木康成, 大森亨, 山岡利光, 廣瀬敬, 他
- Organizer
  (肺癌52巻5号Page625)
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] FGFR-TKIの再投与の有効性と安全性の検討2012
- Author(s)
  中嶌賢尚, 大木康成, 村田泰規, 石田孔子, 杉山智英, 石田博雄, 白井崇生, 山岡利光, 奥田健太郎, 大森亨, 大西司, 廣瀬敬
- Organizer
  第53回日本肺癌学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] EGFR遺伝子変異陽性肺腺癌患者に対するゲフィチニブとゾレドロン酸併用療法の有用性に関する後方視的解析2012
- Author(s)
  大木康成, 廣瀬敬, 村田泰規, 杉山智英, 楠本壮二郎, 石田博雄, 白井崇生, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨
- Organizer
  第53回日本肺癌学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 糖尿病合併肺癌の現状について2012
- Author(s)
  楠本壮二郎, 廣瀬敬, 山岡利光, 大森亨, 他
- Organizer
  (日本呼吸器学会誌1巻増刊Page319)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 切除不能局所進行非小細胞肺癌に対する胸部放射線療法とvinorelbine, carboplatin同時併用第II相試験2012
- Author(s)
  廣瀬敬, 山岡利光, 大森亨, 他
- Organizer
  (日本呼吸器学会誌1巻増刊Page326)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] Carboplatin+Paclitaxel+Bevacizumabによる化学療法中にIII度房室ブロックをきたした肺腺癌症例2012
- Author(s)
  白井崇生, 廣瀬敬, 大木康成, 村田泰規, 楠本壮二郎, 杉山智英, 石田博雄, 中嶌賢尚, 奥田健太郎, 大西司, 足立満, 山岡利光, 大森亨
- Organizer
  第53回日本肺癌学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 当院におけるCOPD合併切除不能非小細胞肺癌に関する検討2012
- Author(s)
  杉山智英, 大森亨, 山岡利光, 廣瀬敬, 他
- Organizer
  (肺癌52巻5号Page775)
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] FGFR-TKIの再投与の有効性と安全性の検討.2012
- Author(s)
  中嶌賢尚, 大森亨, 山岡利光, 廣瀬敬, 他
- Organizer
  (肺癌52巻5号Page621)
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 切除不能局所進行非小細胞肺癌に対する胸部放射線療法とvinorelbine, carboplatin同時併用第II相試験2012
- Author(s)
  大森亨, 山岡利光, 廣瀬敬, 他
- Organizer
  (肺癌52巻5号Page579)
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 気道上皮細胞と非小細胞肺癌細胞におけるTACEを介したTNFによるEGFRのトランス活性化機序の検討2012
- Author(s)
  山岡利光, 村田泰規, 大木康成, 楠本壮二郎, 杉山智英, 白井崇生, 中嶌賢尚, 奥田健太郎, 大西司, 大森亨, 廣瀬敬, 足立満
- Organizer
  日本呼吸器学会学術講演会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21790788
[Presentation] 当院におけるCOPD合併切除不能非小細胞肺癌に関する検討2012
- Author(s)
  杉山智英, 廣瀬敬, 大木康成, 村田泰規, 楠本壮二郎, 石田博雄, 白井崇生, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 濱田健司
- Organizer
  第53回日本肺癌学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] SPC/TNFトランスジエニックマウスモデルにおけるEGFRチロシンキナーゼ阻害剤による肺組織のアポトーシス誘導機構の検討2012
- Author(s)
  山岡利光, 大木康成, 村田泰規, 杉山智英, 石田博雄, 白井崇生, 中属賢尚, 奥田健太郎, 大西司, 慶瀬敬, 大森亨
- Organizer
  日本呼吸器学会学術集会
- Place of Presentation
  東京
- Year and Date
  2012-04-19
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] 気道上皮細胞と非小細胞肺癌細胞におけるTACEを介したTNFによるEGFRのトランス活性化機序の検討2012
- Author(s)
  山岡利光
- Organizer
  第52回日本呼吸器学会学術講演会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21790788
[Presentation] 進展型小細胞肺癌の生存期間に対するアムルビシンの影響に関する検討2012
- Author(s)
  石田博雄, 大木康成, 村田泰規, 石田孔子, 楠本壮二郎, 杉山智英, 白井崇生, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 廣瀬敬
- Organizer
  第53回日本肺癌学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 気道上皮細胞と非小細胞肺癌細胞におけるTACEを介したTNFによるEGFRのトランス活性化機序の検討2012
- Author(s)
  山岡利光, 村廣瀬敬, 山岡利光, 大森亨, 他
- Organizer
  (日本呼吸器学会誌1巻増刊Page323)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 高齢者進行非小細胞肺癌のnedaplatin+gemcitabine併用療法の有効性と安全性のレトロスペクティブ検討2012
- Author(s)
  山岡利光, 村田泰規, 大木康成, 楠本壮二郎, 杉山智英, 白井崇生, 中嶌賢尚, 奥田健太郎, 大西司, 大森亨, 廣瀬敬, 足立満
- Organizer
  日本呼吸器学会
- Place of Presentation
  兵庫、神戸
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 当院におけるCOPD合併肺癌手術例に関する検討2012
- Author(s)
  杉山智英, 廣瀬敬, 村田泰規, 大木康成, 楠本壮二郎, 石田博雄, 白井崇生, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 門倉光隆, 大森亨, 足立満
- Organizer
  日本呼吸器学会
- Place of Presentation
  兵庫、神戸
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 高齢者小細胞肺癌に対する治療成績の検討2012
- Author(s)
  村田泰規, 廣瀬敬, 大木康成, 杉山智英, 石田博雄, 白井崇生, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨
- Organizer
  第53回日本肺癌学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] Carboplatin+Paclitaxel+Bevacizumabによる化学療法中にIII度房室プロックをきたした肺腺癌症例2012
- Author(s)
  白井崇生, 慶瀬敬, 大木康成, 村田泰規, 楠本壮三郎, 杉山智英, 石田博雄, 中属賢尚, 奥田健太郎, 大西司, 足立満, 山岡利光, 大森亨
- Organizer
  日本肺癌学会
- Place of Presentation
  岡山
- Year and Date
  2012-11-08
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] A novel c-MET inhibitor, tivantinib, shows an additive growth-inhibitory effect with erlotinib through enhanced degradation of c-MET protein via its recycling pathway2012
- Author(s)
  210. Tohru Ohmori, Tomoko Kanome, Toshimitsu Yamaoka, Takashi Hirose, Fumiaki Koizumi, Kazuto Nishio, Shiro Akinaga
- Organizer
  19th International Charles Heidelberger Symposium on Cancer Research
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 標準治療不応進行非小細胞肺癌に対するペプチドワクチン療法(Cancer vaccination trial with novel mult iple peptides in previously treated advanced non-small-cell lung cancer (NSCLC))2012
- Author(s)
  慶瀬敬, 野田秀裕, 奥田健太郎, 阿部誠治, 大戸祐治, 杉山智英, 石田博雄, 白井崇生, 中属賢尚, 山岡利光, 大森亨, 吉田浩三, 中村祐輔
- Organizer
  日本癌学会
- Place of Presentation
  札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] Specific epidermal growth factor receptor autophosphorylation sites promote epithelial cell chemotaxis and restitution2012
- Author(s)
  Tohru Ohmori, Toshimitsu Yamaoka, Takashi Hirose, et al
- Organizer
  103rd Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 切除不能局所進行非小細胞肺癌に対する胸部放射線療法とvinorelbine、carboplatin同時併用第II相試験2012
- Author(s)
  廣瀬敬, 村田泰規, 大木康成, 杉山智英, 楠本壮二郎, 石田博雄, 白井崇生, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨
- Organizer
  第53回日本肺癌学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] HSP 70 may cause EGFR-TKIs-resistance due to inhibit drug binding to EGFR in the cells that expressed mutant EGFR2012
- Author(s)
  Tohru Ohmori, Tsuyoki Kadofuku, Yoko Ichihashi, Toshimitsu Yamaoka, Takashi Hirose, Mitsuru Adachi, Nagahiro Saijo
- Organizer
  103rd Meeting of American Association for Cancer Research
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] Carboplatin+Paclitaxel+ Bevacizumabによる化学療法中にIII度房室ブロックをきたした肺腺2012
- Author(s)
  白井崇生, 大森亨, 山岡利光, 廣瀬敬, 他
- Organizer
  (癌症例肺癌52巻3号Page359-360)
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 糖尿病合併肺癌の現状について2012
- Author(s)
  楠本壮二郎, 大木康成, 村田泰規, 杉山智英, 石田博雄, 白井崇生, 中嶌賢尚, 山岡利光, 奥田健太郎, 廣瀬敬, 大西司, 大森亨, 足立満
- Organizer
  日本呼吸器学会
- Place of Presentation
  兵庫、神戸
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 進展型小細胞肺癌の生存期間に対するアムルビシンの影響に関する検討2012
- Author(s)
  石田博雄, 大森亨, 山岡利光, 廣瀬敬, 他
- Organizer
  (肺癌52巻5号Page586)
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] Specific epidermal growth factor receptor autophosphorylation sites promote epithelial cell chemotaxis and restitution2012
- Author(s)
  Toshimitsu Yamaoka, Mark Frey, D. Brent Polk, Tohru Ohmori et al
- Organizer
  103rd Meeting of American Association for Cancer Research
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] Specific epidermal growth factor receptor autophosphorylation sites promote epithelial cell chemotaxis and restitution.2012
- Author(s)
  山岡利光
- Organizer
  AACR 2012
- Place of Presentation
  シカゴ
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] Cancer Vaccination trial with novel multiple peptides in previously treated advanced non-small cell lung cancer2012
- Author(s)
  Tohru Ohmori, Toshimitsu Yamaoka, Takashi Hirose, et al
- Organizer
  Annual Meeting of American Society of Clinical Oncology
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 高齢者進行非小細胞肺癌のnedaplatin+gemcitabine併用療法の有効性と安全性のレトロスペクティブ検討2012
- Author(s)
  中嶌賢尚, 廣瀬敬, 山岡利光, 大森亨, 他
- Organizer
  (日本呼吸器学会誌1巻増刊Page264)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 進展型小細胞肺癌の生存期間に対するアムルビシンの影響に関する検討2012
- Author(s)
  石田博雄, 大森亨, 山岡利光, 廣瀬敬, 他
- Organizer
  (日本癌治療学会誌47巻3号Page2134)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 高齢者小細胞肺癌に対する治療成績の検討2012
- Author(s)
  村田泰規, 大森亨, 山岡利光, 廣瀬敬, 他
- Organizer
  (肺癌52巻5号Page637)
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 進行肺大細胞神経内分泌癌と進展型小細胞肺癌に対する化学療法の有効性の比較2012
- Author(s)
  石田博雄, 大森亨, 山岡利光, 廣瀬敬, 他
- Organizer
  (肺癌52巻5号Page598)
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] Specific epidermal growth factor receptor autophosphorylation sites promote epithelial cell chemotaxis and restitution2012
- Author(s)
  Toshimitsu Yamaoka, Mark Frey, D. Brent Polk, Yasunari Oki, Yasunori Murata, Tomohide Sugiyama, Sojiro Kusumoto, Hiroo Ishida, Takao Shirai, Masanao Nakashima, Kentaro Okuda, Tsukasa Ohnishi, Takashi Hirose, Tohru Ohmori and Mitsuru Adachi
- Organizer
  103rd Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-21790788
[Presentation] 進展型小細胞肺癌の生存期間に対するアムルビシンの影響に関する検討2012
- Author(s)
  202. 石田博雄, 大木康成, 村田泰規, 石田孔子, 楠本壮二郎, 杉山智英, 白井崇生, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 廣瀬敬
- Organizer
  第50回日本癌治療学会総会
- Place of Presentation
  神奈川、横浜
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] HSP 70 may cause EGFR-TKIs-resistance due to inhibit drug binding to EGFR in the cells that expressed mutant EGFR2012
- Author(s)
  Tohru Ohmori, Toshimitsu Yamaoka, Takashi Hirose, et al
- Organizer
  Proceedings of American Association for Cancer Research, #1900
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] Specific epidermal growth factor receptor autophosphorylation sites promote epithelial cell chemotaxis and restitution2012
- Author(s)
  山岡利光
- Organizer
  AACR 2012
- Place of Presentation
  シカゴ
- Data Source
  KAKENHI-PROJECT-21790788
[Presentation] 切除不能局所進行非小細胞肺癌に対する胸部放射線療法とvinorelbine、carboplatin同時併用第II相試験2012
- Author(s)
  廣瀬敬, 大木康成, 村田泰規, 杉山智英, 楠本壮二郎, 石田博雄, 白井崇生, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 足立満
- Organizer
  日本呼吸器学会
- Place of Presentation
  兵庫、神戸
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] EGFR遺伝子変異陽性の肺腺癌患者に対する、ゲフィチニプとゾレドロン酸併用療法の有用性に関する後方視的解析2012
- Author(s)
  大木康成, 村田泰規, 杉山智英, 楠本壮三郎, 石田博雄, 白井崇生, 中属賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 慶瀬敬
- Organizer
  日本呼吸器学会学術集会
- Place of Presentation
  東京
- Year and Date
  2012-04-19
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] 当院におけるCOPD合併肺癌手術例に関する検討2012
- Author(s)
  杉山智英, 廣瀬敬, 山岡利光, 大森亨, 他
- Organizer
  (日本呼吸器学会誌1巻増刊Page326)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 当院におけるCOPD合併肺癌手術例に関する検討2011
- Author(s)
  杉山智英, 廣瀬敬, 山岡利光, 大森亨, 他
- Organizer
  (肺癌51巻5号Page516)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] HSP70 may cause EGFR-TKIs-resistance due to inhibit drug binding to EGFR in the cell that expressed mutant EGFR2011
- Author(s)
  Tohru Ohmori, Toshimitsu Yamaoka, Takashi Hirose, et al
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋(English oral session E-1017)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 気道上皮細胞と非小細胞肺癌細胞におけるTACE/EGFR-リガンドを介したTNFによるEGFRのトランス活性化の機序の検討2011
- Author(s)
  山岡利光
- Organizer
  日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] 超高齢者進行非小細胞肺癌の治療の有用性と安全性について2011
- Author(s)
  奥田健太郎, 廣瀬敬, 山岡利光, 大森亨, 他
- Place of Presentation
  東京(日本呼吸器学会雑誌49巻増刊Page294)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] HSP70 specifically binds to 15 bp deletion mutant EGFR and modulates sensitivity to EGFR-TKI2011
- Author(s)
  Tsuyoki Kadofuku, Toshimitsu Yamaoka, Takashi Hirose, Tohru Ohmori, et al
- Place of Presentation
  Orland FL, USA(Proceedings of American Association for Cancer Research, Vol. 52 699)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 高齢者進行非小細胞肺癌に対するnedaplatin +gemcitabine併用療法の有効性と安全性の検討2011
- Author(s)
  中嶌賢尚, 廣瀬敬, 山岡利光, 大森亨, 他
- Organizer
  (肺癌51巻5号Page486)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 足立満気道上皮細胞と非小細胞肺癌細胞におけるTACE/EGFR-リガンドを介したTNFによるEGFRのトランス活性化の機序検討(TNF transactivates phospho-tyrosine 1068 of EGFR through TACE/EGFR-ligand dependent mechanism)2011
- Author(s)
  山岡利光, 大木康成, 楠本壮二郎, 杉山智英, 白井崇生, 中嶌賢尚, 奥田健太郎, 廣瀬敬, 大森亨, 大西司
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21790788
[Presentation] EGFR-TKI耐性細胞に対するARQ197のMet阻害機構2011
- Author(s)
  大森亨, 山岡利光, 廣瀬敬, 他
- Organizer
  第15回がん分子標的治療研究会総会
- Place of Presentation
  東京(ワークショップW6-4)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 糖尿病合併肺癌の現状について2011
- Author(s)
  楠本壮二郎, 廣瀬敬, 山岡利光, 大森亨, 他
- Organizer
  (肺癌51巻5号Page495)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] IV期非小細胞肺がんにおける末梢血中がん細胞数(CTC)と抗がん剤治療の効果と予後との関連性2011
- Author(s)
  廣瀬敬, 山岡利光, 大森亨, 他
- Organizer
  (肺癌51巻5号Page421)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 再発あるいは前治療無効小細胞肺癌(SCLC)に対するamrubicin, carboplatin併用第II相試験2011
- Author(s)
  廣瀬敬, 山岡利光, 大森亨, 他
- Place of Presentation
  東京(日本呼吸器学会雑誌49巻増刊Page295)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 発熱性好中球減少症におけるプロカルシトニンの有用性の検討2011
- Author(s)
  杉山智英, 廣瀬敬, 山岡利光, 大森亨, 他
- Place of Presentation
  東京(日本呼吸器学会雑誌49巻増刊Page162)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 気道上皮細胞と非小細胞肺癌細胞におけるTACE/EGFR-リガンドを介したTNFによるEGFRのトランス活性化の機序検討(TNF transactivates phospho-tyrosine 1068 of EGFR through TACE/EGFR-ligand dependent mechanism)2011
- Author(s)
  山岡利光, 大木康成, 楠本壮三郎, 杉山智英, 白井崇生, 中属賢尚, 奥田健太郎, 慶瀬敬, 大森亨, 大西司, 足立満
- Organizer
  日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] TNF transactivates phospho-tyrosine 1068 of EGFR through TACE/EGFR-ligand dependent mechanism2011
- Author(s)
  Toshimitsu Yamaoka, Takashi Hirose, Tohru Ohmori, et al
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋(P-2051)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 気道上皮細胞と非小細胞肺癌細胞におけるTACE/EGFR-リガンドを介したTNFによるEGFRのトランス活性化の機序の検討2011
- Author(s)
  山岡利光
- Organizer
  日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21790788
[Presentation] 気道上皮細胞と胞肺癌細胞におけるTNFによるEGFRのトランス活性化に寄与するリガンドの同定とアポトーシス制御機構2011
- Author(s)
  山岡利光
- Organizer
  日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2011-04-01
- Data Source
  KAKENHI-PROJECT-21790788
[Presentation] 気道上皮細胞と肺癌細胞におけるTNFによるEGFRトランス活性化に寄与するリガンドの同定とアポトーシス制御機構2011
- Author(s)
  山岡利光, 大森亨, 廣瀬敬, 他
- Place of Presentation
  東京(日本呼吸器学会雑誌49巻増刊Page159)
- Data Source
  KAKENHI-PROJECT-23590308
[Presentation] 進行非小細胞肺癌の生存期間が延長しているのはなぜか?2010
- Author(s)
  白井崇生, 慶瀬敬, 楠本壮三郎, 杉山智英, 中属賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 足立満
- Organizer
  日本肺癌学会
- Place of Presentation
  東京
- Year and Date
  2010-11-12
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] Transactivation of EGFR/ErbB2 receptor by TNF abrogates TNF-induced apoptosis in bronchial epithelial cells and non-small cell ling cancer2010
- Author(s)
  山岡利光
- Organizer
  第101回米国癌学会(AACR)
- Place of Presentation
  ワシントンDC(米国)
- Year and Date
  2010-04-21
- Data Source
  KAKENHI-PROJECT-21790788
[Presentation] Transactivation of EGFR/ErbB2 receptor by TNF abrogates TNF-induced apoptosis in bronchial epithelial cells and non-small cell ling cancer2010
- Author(s)
  山岡利光
- Organizer
  第101回米国癌学会(AACR)
- Place of Presentation
  ワシントンDC(米国)
- Year and Date
  2010-04-21
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] TACEを介したEGFRトランス活性化の気道上皮細胞と非小細胞肺癌細胞におけるTNF誘導アポトーシス制御機構の検討2010
- Author(s)
  山岡利光
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22501051
[Presentation] TACEを介したEGFRトランス活性化の気道上皮細胞と非小細胞肺癌細胞におけるTNF誘導アポトーシス制御機構の検討2010
- Author(s)
  山岡利光
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21790788
[Presentation] Tyrosine site-specific phosphory lation of EGF receptor by TNF-induced transactivation regulates EGFR-ErbB2 intestinal epithelial cell anti-apoptosis2009
- Author(s)
  山岡利光
- Organizer
  第100回アメリカ癌学会(AACR)
- Place of Presentation
  アメリカ(デンバー)
- Data Source
  KAKENHI-PROJECT-21790788
[Presentation] TNFによるEGFRとErbB2のトランス活性化に寄与するEGFRチロシンキナーゼの同定とアポトーシス制御機構2009
- Author(s)
  山岡利光
- Organizer
  第68回日本癌学会
- Place of Presentation
  神奈川県(横浜)
- Data Source
  KAKENHI-PROJECT-21790788
[Presentation] TNF transactivation of EGFR protects EGFR-TKI, gefitinib induced pulmonary epithelial cell apoptosis and injury in TNF transgenic mice
- Author(s)
  山岡利光, 大木康成, 村田泰規, 楠本壮二郎, 石田博雄, 白井崇生, 外谷衣都子, 大場基, 藤田健一, 荒田悟, 大森亨, 大西司, 相良博典, 佐々木康綱
- Organizer
  米国　癌学会 (AACR)
- Place of Presentation
  サンディエゴ
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-25870736
[Presentation] TNF transactivation of EGFR protects EGFR-TKI, gefitinib induced pulmonary epithelial cell apoptosis and injury in TNF transgenic mice
- Author(s)
  山岡利光, 大森亨, 大木康成, 村田泰規, 楠本壮二郎, 石田博雄, 白井崇生, 廣瀬敬, 大西司, 佐々木康綱
- Organizer
  日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25870736
[Presentation] MET高発現を示すEGFR-TKI耐性PC-9細胞におけるMET阻害剤耐性機序の検討
- Author(s)
  山岡利光, 大森亨, 大木康成, 村田泰規, 楠本壮二郎, 石田博雄, 白井崇生, 廣瀬敬, 大西司, 佐々木康綱
- Organizer
  日本肺癌学会
- Place of Presentation
  京都
- Year and Date
  2014-11-14 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-25870736
[Presentation] SPC-TNF トランスジェニックマウスモデルにおけるEGFRチロシンキナーゼ阻害剤による肺組織のアポトーシス誘導機構の検討
- Author(s)
  山岡利光, 外谷衣都子, 大場基, 大木康成, 村田泰規, 楠本壮二郎, 石田博雄, 白井崇生, 大森亨, 佐々木康綱
- Organizer
  日本臨床腫瘍学会
- Place of Presentation
  福岡
- Year and Date
  2014-07-17 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-25870736
[Presentation] 非小細胞肺癌に対するエルロチニブの毒性に影響を与える薬物動態、薬理遺伝学的検討
- Author(s)
  廣瀬敬, 藤田健一, 楠本壮二郎, 白井崇生, 村田泰則, 大木康成, 杉山智英, 石田博雄, 中嶌賢尚, 山岡利光, 奥田健太郎, 大西司, 大森亨, 佐々木康綱, 田村厚久, 大田健
- Organizer
  第54回日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-23590648

1. OHMORI Tohru (10276529)

# of Collaborated Projects: 4 results

# of Collaborated Products: 102 results
2. HIROSE Takashi (40307038)

# of Collaborated Projects: 3 results

# of Collaborated Products: 76 results
3. ADACHI Mitsuru (10095870)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. 佐々木康綱 (20235279)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. SIRAI Takao (90384362)

# of Collaborated Projects: 1 results

# of Collaborated Products: 22 results
6. KADOKURA Mitsutaka (60214417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 藤田健一 (60281820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 荒田悟 (20159502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 本間まゆみ (20527171)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 楠本壮二郎 (30465091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
11. 中嶌賢尚 (90365768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 長谷部友紀 (90623843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KAMEI Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 大場基

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 加賀美芳和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamaoka Toshimitsu 山岡 利光

山岡 利光 ヤマオカ トシミツ

YAMAOKA Toshimitsu 山岡 利光

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Development of the new technique for capturing circulating tumor cells of non-small cell lung cancer.

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Investigate the role of TNF and EGFR in the onset and progression of lung cancer complicated with COPDPrincipal Investigator

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The potential mechanisms of EGFR-TKI induced lung injury in mice modelPrincipal Investigator

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Elucidation of trans-activation mechanism from TRAIL receptor to EGFR

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Association of pharmacokinetics or pharmacogenomics with toxicity of erlotinib in patients with advanced non-small cell lung cancer

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The role of ADAM17 in squamous cell lung cancer

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TNF induced lung injury was protected by EGFR transactivationPrincipal Investigator

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[Book] EGFR阻害剤の耐性とその克服(The mechanisms of resistance to EGFR-TKIs and challenges to overcome resistance in EGFR mutant Non-small cell lung cancer)(39巻6号)2012

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[Book] 癌と化学療法2012

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[Book] 癌と化学療法2012

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[Journal Article] KRAS and EGFR Amplifications Mediate Resistance to Rociletinib and Osimertinib in Acquired Afatinib-Resistant NSCLC Harboring Exon 19 Deletion/T790M in EGFR2018

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[Journal Article] Receptor Tyrosine Kinase-Targeted Cancer Therapy2018

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[Journal Article] Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure.2017

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[Journal Article] Distinct Afatinib Resistance Mechanisms Identified in Lung Adenocarcinoma Harboring an EGFR Mutation.2017

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Yamaoka Toshimitsu 山岡利光

山岡利光ヤマオカトシミツ

YAMAOKA Toshimitsu 山岡利光