Umedu Tomohiro 梅津知宏

… Alternative Names

UMEZU Tomohiro 梅津知宏

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Researcher Number	40385547
Other IDs	https://orcid.org/0000-0002-0123-8921
Affiliation (Current)	2025: 東京医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2025: 東京医科大学, 医学部, 講師 2023: 東京医科大学, 医学部, 講師 2019 – 2022: 東京医科大学, 医学部, 准教授 2014 – 2018: 東京医科大学, 医学部, 講師 2017: 東京医科大学, 医学部, 講師(特任) … More 2011 – 2013: 東京医科大学, 医学部, 助教 2009: 東京理科大学, 基礎工学部・生物工学科, 助教 2007 – 2008: 東京理科大学, 基礎工学部, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Tumor biology / Tumor diagnosis Except Principal Investigator Basic Section 49020:Human pathology-related / Laboratory medicine / Tumor therapeutics / Tumor diagnostics / Tumor diagnosis / Morphology/Structure
Keywords	Principal Investigator 多発性骨髄腫 / miRNA / エクソソーム / がん微小環境 / がん間質 / 加齢性変化 / 前がん病変 / エクソーム解析 / 体細胞変異 / 加齢性変異 … More / mutational signature / cell free DNA / MGUS / セクレトーム解析 / セクレトーム / 加齢 / 骨髄内微小環境 / aging / 骨髄間質細胞 / 細胞外小胞 / 細胞間相互作用 / 低酸素環境 / 血管新生 / 骨髄異形成症候群 / 一分子蛍光分析法 / DNA脱メチル化薬 / メチル化DNA / MBD2 / 1分子蛍光分析法 / 脱メチル化薬 / DNA メチル化 / ゲノム … More Except Principal Investigator miRNA / エクソソーム / 骨髄間質細胞 / 骨髄異形成症候群 / DICER1 / miRNA-122 / miRNA-5p / non-coding RNA / lncRNA / miR-122 / miR-5p / DICER1症候群 / 肝腫瘍 / Docer1症候群 / 一次線毛 / 胆管癌 / Prkcsh / PKD1 / 一次繊毛 / 肝間葉性過誤腫 / Dicer1症候群 / リキッドバイオプシー / 造血幹細胞移植 / 移植片対宿主病 / 加齢 / 腫瘍血管新生 / 多発性骨髄腫 / 造血器腫瘍 / 細胞外小胞 / 5-azacytidine / telomere RNA / DNAメチル化 / 骨髄不全症候群 / 5-アザシチジン / テロメアRNA / クローン性株細胞 / p53欠損マウス / クローン株細胞 / 間充織因子 / 形態形成 / 上皮・間充織相互作用 Less

老化ステータス異常がCAFの多様性に与える影響とその役割の解明Principal Investigator
- Principal Investigator
  
  梅津知宏
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tokyo Medical University
Analysis of the mechanism of ncRNA-mediated carcinogenesis using the DICER1 syndrome model
- Principal Investigator
  
  Kuroda Masahiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Tokyo Medical University
Analysis of age-related genetic changes in non-tumour tissues - Investigating links to mechanisms of cancer-associated fibroblast developmentPrincipal Investigator
- Principal Investigator
  
  Umezu Tomohiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tokyo Medical University
Secretome analysis of tumor stroma involved in the process of cancer progressionPrincipal Investigator
- Principal Investigator
  
  Umezu Tomohiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tokyo Medical University
Novel therapies development of multiple myeloma using engineering exosomes derived from bone marrow stromal cells
- Principal Investigator
  
  Ohyashiki Junko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Tokyo Medical University
Analysis of novel pathogenesis of cancer-associated fibroblast involved in age-related stromal exosome changesPrincipal Investigator
- Principal Investigator
  
  Umezu Tomohiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Tokyo Medical University
Development of novel diagnostics for hematological malignancy on basis of the exosome analysis
- Principal Investigator
  
  Ohyashiki Kazuma
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Tokyo Medical University
Altered Exosomal miRNA expression of late onset acute graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.
- Principal Investigator
  
  Yoshizawa Seiichiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical University
Cell-to-cell communication between tumor cell and their microenvironment via exosomesPrincipal Investigator
- Principal Investigator
  
  UMEZU Tomohiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Tokyo Medical University
Telomere repeat-containing RNA (TERRA), a possible molecular marker of leukemia
- Principal Investigator
  
  OHYASHIKI Junko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnosis
- Research Institution
  Tokyo Medical University
Detection method for quantifying global DNA methylation byfluorescence correlation spectroscopyPrincipal Investigator
- Principal Investigator
  
  UMEZU Tomohiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor diagnosis
- Research Institution
  Tokyo Medical University
Mechanisms determining epithelial cell fate decisions by mesenchyme
- Principal Investigator
  
  TOMOOKA Yasuhiro
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphology/Structure
- Research Institution
  Tokyo University of Science

[Journal Article] Plasma extracellular vesicle microRNAs reflecting the therapeutic effect of the CBP/β-catenin inhibitor PRI-724 in patients with liver cirrhosis.2024
- Author(s)
  Yoshida M, Matsuzaki J, Fujita K, Kimura M, Umezu T, Tokuda N, Yamaguchi T, Kuroda M, Ochiya T, Saito Y, Kimura K.
- Journal Title
  
  Sci Rep.
  
  Volume: 14(1) Issue: 1 Pages: 6266-6266
- DOI
  10.1038/s41598-024-56942-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07133, KAKENHI-PROJECT-21H02706, KAKENHI-PROJECT-23K24188
[Journal Article] Potent antitumor effects of the conditioned medium of bone marrow-derived mesenchymal stem cells via IGFBP-4.2023
- Author(s)
  Furusaka Y, Inoue S, Mizoguchi I, Hasegawa H, Katahira Y, Watanabe A, Sakamoto E, Sekine A, Miyakawa S, Umezu T, Owaki T, Yoneto T, Yoshimoto T.
- Journal Title
  
  Cancer Sci.
  
  Volume: in press Issue: 6 Pages: 2499-2514
- DOI
  10.1111/cas.15789
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07504, KAKENHI-PROJECT-22K08018, KAKENHI-PROJECT-22K15696, KAKENHI-PROJECT-22K16291, KAKENHI-PROJECT-22K08722, KAKENHI-PROJECT-22K12772, KAKENHI-PROJECT-23K09087, KAKENHI-PROJECT-21K07133, KAKENHI-PROJECT-21K09779, KAKENHI-PROJECT-21K12256
[Journal Article] miR-146a-5p and miR-191-5p as novel diagnostic marker candidates for ovarian clear cell carcinoma.2023
- Author(s)
  Takamizawa S, Kojima J, Umezu T, Kuroda M, Hayashi S, Maruta T, Okamoto A, Nishi H.
- Journal Title
  
  Mol Clin Oncol.
  
  Volume: 20(2) Issue: 2 Pages: 14-14
- DOI
  10.3892/mco.2023.2712
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07133, KAKENHI-PROJECT-21H02706
[Journal Article] Effect of COVID-19 infection on the gastrointestinal tract considering preventive methods during endoscopic procedures.2023
- Author(s)
  Naito S, Nakamura I, Umezu T, Hata A, Madarame A, Uchida K, Koyama Y, Morise T, Yamaguchi H, Kono S, Sugimoto M, Kawai T, Harada Y, Kuroda M, Fukuzawa M, Itoi T.
- Journal Title
  
  DEN Open.
  
  Volume: 4(1) Issue: 1
- DOI
  10.1002/deo2.290
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07133
[Journal Article] Characterization of circulating <scp>miRNAs</scp> in the treatment of primary liver tumors2023
- Author(s)
  Umezu Tomohiro、Tanaka Shogo、Kubo Shoji、Enomoto Masaru、Tamori Akihiro、Ochiya Takahiro、Taguchi Y.‐H.、Kuroda Masahiko、Murakami Yoshiki
- Journal Title
  
  Cancer Reports
  
  Volume: 7 Issue: 2 Pages: 1-9
- DOI
  10.1002/cnr2.1964
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12067, KAKENHI-PROJECT-21K07133, KAKENHI-PROJECT-21H02706
[Journal Article] Optimal DNA quality preservation process for comprehensive genomic testing of pediatric clinical autopsy formalin-fixed, paraffin-embedded tissues.2022
- Author(s)
  Watanabe N, Umezu T, Kyushiki M, Ichimura K, Nakazawa A, Kuroda M.
- Journal Title
  
  Pol J Pathol
  
  Volume: 73(3) Issue: 3 Pages: 255-263
- DOI
  10.5114/pjp.2022.124492
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07133, KAKENHI-PROJECT-20K16869
[Journal Article] Multiple cancer type classification by small RNA expression profiles with plasma samples from multiple facilities2022
- Author(s)
  Suzuki K, Igata H, Abe M, Yamamoto Y; small RNA based cancer classification project.
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 6 Pages: 2144-2166
- DOI
  10.1111/cas.15309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H01076, KAKENHI-PROJECT-21H02706, KAKENHI-PROJECT-19K07740, KAKENHI-PROJECT-20K07336, KAKENHI-PROJECT-20K09422, KAKENHI-PROJECT-21K07133, KAKENHI-PROJECT-19KT0019
[Journal Article] Comprehensive Gene Analysis of IgG4-Related Ophthalmic Disease Using RNA Sequencing2021
- Author(s)
  Asakage M, Usui Y, Nezu N, Shimizu H, Tsubota K, Umazume K, Yamakawa N, Umezu T, Suwanai H, Kuroda M, Goto H.
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: in press Issue: 11 Pages: 3548-3548
- DOI
  10.3390/jcm9113458
- NAID
  120007183860
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09959, KAKENHI-PROJECT-19K09981, KAKENHI-PROJECT-18K07244
[Journal Article] Acerola exosome-like nanovesicles to systemically deliver nucleic acid medicine via oral administration.2021
- Author(s)
  Umezu T, Takanashi M, Murakami Y, Ohno SI, Kanekura K, Sudo K, Nagamine K, Takeuchi S, Ochiya T, Kuroda M.
- Journal Title
  
  Molecular therapy. Methods & clinical development.
  
  Volume: 10;21 Pages: 199-208
- DOI
  10.1016/j.omtm.2021.03.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08382, KAKENHI-PROJECT-20H03593, KAKENHI-PROJECT-21H02706
[Journal Article] Effect of the extracellular componebt of bone marrow mesenchymal stromal cells from healthy donors on hematologic neoplasms and their angiogenesis.2020
- Author(s)
  Gladkov N, Umezu T, Imanishi S, Kawana C, Ohyashiki JH, Ohyashiki K.
- Journal Title
  
  Hum Cell.
  
  Volume: 33(3) Issue: 3 Pages: 599-609
- DOI
  10.1007/s13577-020-00332-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07244
[Journal Article] Downregulation of extracellular vesicle microRNA-101 derived from bone marrow mesenchymal stromal cells in myelodysplastic syndrome with disease progression.2020
- Author(s)
  Saitoh Y, Umezu T, Imanishi S, Asano M, Yoshizawa S, Katagiri S, Suguro T, Fujimoto H, Akahane D, Kobayashi-Kawana C, Ohyashiki JH, Ohyashiki K.
- Journal Title
  
  Oncol Lett.
  
  Volume: 19(3) Pages: 2053-2061
- DOI
  10.3892/ol.2020.11282
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07244, KAKENHI-PROJECT-19K16811
[Journal Article] Comprehensive analysis of liver and blood miRNA in precancerous conditions2020
- Author(s)
  Umezu Tomohiro、Tsuneyama Koichi、Kanekura Kohsuke、Hayakawa Michiyo、Tanahashi Toshihito、Kawano Mitsuoki、Taguchi Y-h、Toyoda Hidenori、Tamori Akihiro、Kuroda Masahiko、Murakami Yoshiki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 21766-21766
- DOI
  10.1038/s41598-020-78500-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12067, KAKENHI-PROJECT-20H03593, KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-18K07244, KAKENHI-PUBLICLY-19H05270, KAKENHI-PUBLICLY-20H04848
[Journal Article] BIM deletion polymorphism accounts for lack of favorable outcome in Japanese females with follicular lymphoma.2019
- Author(s)
  Ito Y, Umezu T, Tadokoro K, Saito Y, Katagiri S, Suguro T, Asano M, Yoshizawa S, Akahane D, Tanaka Y, Fujimoto H, Okabe S, Gotoh M, Tauchi T, Kawana C, Ohyashiki JH, Nakamura N, Ohyashiki K.
- Journal Title
  
  Leuk Lymphoma.
  
  Volume: 60(5) Issue: 5 Pages: 1283-1288
- DOI
  10.1080/10428194.2018.1529310
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15656, KAKENHI-PROJECT-18K07244
[Journal Article] Lineage-specific RUNX2 super-enhancer activates MYC via a chromosomal translocation and promotes the development of blastic plasmacytoid dendritic cell neoplasm2019
- Author(s)
  Kubota S, Tokunaga K, Umezu T, Yokomizo-Nakano T, Oshima M, Tan KT, Yang H, Kanai A. Iwanaga E, Asou N, Maeda T, Nakagata N. Ito T, Iwama A. Ohyashiki K, Osato M, Sashida G.
- Journal Title
  
  Nat Commun
  
  Volume: 10 Issue: 1 Pages: 1653-1653
- DOI
  10.1038/s41467-019-09710-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18K07244, KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-19K22640, KAKENHI-PROJECT-18K16090, KAKENHI-PROJECT-18K18196, KAKENHI-PROJECT-18H02842, KAKENHI-PROJECT-17J02389
[Journal Article] Predisposed genomic instability in pre-treatment bone marrow evolves to therapy-related myeloid neoplasms in malignant lymphoma.2019
- Author(s)
  Katagiri S, Makishima H, Azuma K, Nannya Y, Saitoh Y, Yoshizawa S, Akahane D, Fujimoto H, Ito Y, Velaga R, Umezu T, Ohyashiki JH, Ogawa S, Ohyashiki K.
- Journal Title
  
  Haematologica.
  
  Volume: Nov 7 Issue: 7 Pages: 229856-229856
- DOI
  10.3324/haematol.2019.229856
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07244, KAKENHI-PROJECT-19K16811, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H01053
[Journal Article] Maintenance 5-azacytidine therapy by MRD monitoring after allogeneic HSCT in myeloid/lymphoid neoplasms with FGFR1 rearrangement.2019
- Author(s)
  Katagiri S, Umezu T, Azuma K, Kobayashi C, Akahane D, Suguro T, Furuya N, Fujimoto H, Nakamura N, Ohyashiki JH, Ohyashiki K.
- Journal Title
  
  Bone Marrow Transplant.
  
  Volume: - Issue: 7 Pages: 1148-1150
- DOI
  10.1038/s41409-019-0436-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07244, KAKENHI-PROJECT-16K07183
[Journal Article] A novel non-invasive monitoring assay of 5-azacitidine efficacy using global DNA methylation of peripheral blood in myelodysplastic syndrome.2019
- Author(s)
  Asano M, Ohyashiki JH, Kobayashi-Kawana C, Umezu T, Imanishi S, Azuma K, Akahane D, Fujimoto H, Ito Y, Ohyashiki K.
- Journal Title
  
  Drug Des Devel Ther.
  
  Volume: 13 Pages: 1821-1833
- DOI
  10.2147/dddt.s195071
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07244
[Journal Article] Induction of multiple myeloma bone marrow stromal cell apoptosis by inhibiting extracellular vesicle miR-10a secretion.2019
- Author(s)
  Umezu T, Imanishi S, Yoshizawa S, Kawana C, Ohyashiki JH, Ohyashiki K.
- Journal Title
  
  Blood Advances
  
  Volume: 3(21) Issue: 21 Pages: 3228-3240
- DOI
  10.1182/bloodadvances.2019000403
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07244
[Journal Article] Exosomal miRNA Signatures for Late-Onset Acute Graft-Versus-Host Disease in Allogenic Hematopoietic Stem Cell Transplantation.2018
- Author(s)
  Yoshizawa S, Umezu T, Saitoh Y, Gotoh M, Akahane D, Kobayashi C, Ohyashiki JH, Ohyashiki K.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 19(9) Issue: 9 Pages: 2493-2493
- DOI
  10.3390/ijms19092493
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07244, KAKENHI-PROJECT-16K07183, KAKENHI-PROJECT-17K15656
[Journal Article] Extracellular vesicle (EV)- mediated cell-cell communication in hematologic neoplasms2018
- Author(s)
  Ohyashiki JH, Umezu T, Ohyashiki K
- Journal Title
  
  Philosophical Transactions of the Royal Society B: Biological Sciences
  
  Volume: 373 Issue: 1737 Pages: 1737-1737
- DOI
  10.1098/rstb.2016.0484
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04303, KAKENHI-PROJECT-15K06841, KAKENHI-PROJECT-18K07244, KAKENHI-PROJECT-16K07183
[Journal Article] Chromatin Regulation by HP1γ Contributes to Survival of 5-Azacytidine-Resistant Cells.2018
- Author(s)
  Imanishi S, Umezu T, Kobayashi C, Ohta T, Ohyashiki K, Ohyashiki JH.
- Journal Title
  
  Front Pharmacol.
  
  Volume: 9 Pages: 1166-1166
- DOI
  10.3389/fphar.2018.01166
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07244, KAKENHI-PROJECT-17H03585, KAKENHI-PROJECT-16K07183, KAKENHI-PROJECT-17K15656
[Journal Article] Stratification of mouse vaginal epithelium 2. Identification of factors inducing stratification2018
- Author(s)
  Takashina R, Nakajima T, Umezu T, Murakami Y, Tomooka Y.
- Journal Title
  
  Biology of Reproduction
  
  Volume: 99(4) Issue: 4 Pages: 727-734
- DOI
  10.1093/biolre/ioy113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07244, KAKENHI-PROJECT-16K08248
[Journal Article] Stratification of mouse vaginal epithelium. 1. Development of three-dimensional models in vitro with clonal cell lines2018
- Author(s)
  Ogawa-Tominaga M, Umezu T, Nakajima T, Tomooka Y.
- Journal Title
  
  Biology of Reproduction
  
  Volume: 99(4) Pages: 715-726
- DOI
  10.1093/biolre/ioy114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07244
[Journal Article] Genetic variations of bone marrow mesenchymal stromal cells derived from acute leukemia and myelodysplastic syndrome by targeted deep sequencing.2017
- Author(s)
  Azuma K, Umezu T, Imanishi S, Asano M, Yoshizawa S, Katagiri S, Ohyashiki K, Ohyashiki JH.
- Journal Title
  
  Leuk Res
  
  Volume: 62 Pages: 23-28
- DOI
  10.1016/j.leukres.2017.09.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07183, KAKENHI-PROJECT-15H04303, KAKENHI-PROJECT-15K06841
[Journal Article] Replenishing exosomes from older bone marrow stromal cells with miR-340 inhibits myeloma-related angiogenesis.2017
- Author(s)
  Umezu T, Imanishi S, Azuma K, Kobayashi C, Yoshizawa S, Ohyashiki K, Ohyashiki JH.
- Journal Title
  
  Blood Adv
  
  Volume: 1(13) Issue: 13 Pages: 812-823
- DOI
  10.1182/bloodadvances.2016003251
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07183, KAKENHI-PROJECT-17K15656, KAKENHI-PROJECT-15H04303, KAKENHI-PROJECT-15K06841
[Journal Article] Extracellular vesicle-mediated cell-cell communication in haematological neoplasms2017
- Author(s)
  Ohyashiki JH, Umezu T, Ohyashiki K.
- Journal Title
  
  Philosophical Transactions B of the Royal Society
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K07183
[Journal Article] Teriflunomide restores 5-azacytidine sensitivity via activation of pyrimidine salvage in 5-azacytidine-resistant leukemia cells.2017
- Author(s)
  Imanishi S, Takahashi R, Katagiri S, Kobayashi C, Umezu T, Ohyashiki K, Ohyashiki JH.
- Journal Title
  
  Oncotarget
  
  Volume: 8(41) Issue: 41 Pages: 69906-69915
- DOI
  10.18632/oncotarget.19436
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07183, KAKENHI-PROJECT-17K15656, KAKENHI-PROJECT-15H04303, KAKENHI-PROJECT-15K06841, KAKENHI-PROJECT-16K19186
[Journal Article] Hidden FLT3-D835Y clone in FLT3-ITD-positive acute myeloid leukemia that evolved into very late relapse with T-lymphoblastic leukemia2017
- Author(s)
  Katagiri S, Umezu T, Asano M, Akahane D, Azuma K, Makishima H, Yoshida K, Watatani Y, Chiba K, Miyano S, Ogawa S, Ohyashiki JH, Ohyashiki K
- Journal Title
  
  Leukemia and Lymphoma
  
  Volume: 3 Issue: 6 Pages: 1-4
- DOI
  10.1080/10428194.2017.1382696
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303, KAKENHI-PROJECT-16H05338, KAKENHI-PROJECT-15K06841, KAKENHI-PROJECT-18K07244, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-16K07183
[Journal Article] Upregulated exosomal miRNA-140-3p in CML patients with musculoskeletal pain associated with discontinuation of tyrosine kinase inhibitors2017
- Author(s)
  Asano M, Umezu T, Katagiri S, Kobayashi C, Tauchi T, Gotoh M, Ando K, Okabe S, Ohyashiki JH, Ohyashiki K
- Journal Title
  
  Int J Hematol
  
  Volume: 105(4) Issue: 4 Pages: 419-422
- DOI
  10.1007/s12185-017-2199-z
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K06841, KAKENHI-PROJECT-16K07183, KAKENHI-PROJECT-17K15656, KAKENHI-PROJECT-15H04303
[Journal Article] Down-regulation of plasma miR-215 in chronic myeloid leukemia patients with successful imatinib discontinuation.2016
- Author(s)
  Ohyashiki K, Umezu T, Katagiri S, Kobayashi C, Azuma K, Tauchi T, Okabe S, Fukuoka Y, Ohyashiki JH
- Journal Title
  
  The International Journal of Molecular Sciences
  
  Volume: 17(4) Issue: 4 Pages: 570-570
- DOI
  10.3390/ijms17040570
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04303, KAKENHI-PROJECT-15K06841
[Journal Article] Exosomes promote bone marrow angiogenesis in hematologic neoplasia: the role of hypoxia.2016
- Author(s)
  Ohyashiki JH, Umezu T, Ohyashiki K
- Journal Title
  
  Curr Opin Hematol
  
  Volume: 23(3) Issue: 3 Pages: 268-273
- DOI
  10.1097/moh.0000000000000235
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06841, KAKENHI-PROJECT-15H04303, KAKENHI-PROJECT-16K07183
[Journal Article] 造血器腫瘍におけるエクソソームを介した細胞間シグナル伝達機構：多発性骨髄腫を中心に2015
- Author(s)
  梅津知宏、大屋敷純子、大屋敷一馬
- Journal Title
  
  血液内科
  
  Volume: 71(3) Pages: 396-400
- NAID
  40020613758
- Data Source
  KAKENHI-PROJECT-15K06841
[Journal Article] Treatment-free molecular remission achieved by combination therapy with imatinib and IFNα in CML with <i>BIM</i> deletion polymorphism relapsed after stop imatinib2015
- Author(s)
  Katagiri S, Tauchi T, Umezu T, Saito Y, Suguro T, Asano M, Yoshizawa S, Kitahara T, Akahane D, Tanaka Y, Fujimoto H, Okabe S, Gotoh M, Ito Y, Ohyashiki JH, Ohyashiki K
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 56 Issue: 2 Pages: 216-219
- DOI
  10.11406/rinketsu.56.216
- NAID
  130004920704
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-15K06841, KAKENHI-PROJECT-26860373
[Journal Article] 造血器腫瘍におけるエクソソームを介した細胞間相互作用機構：多発性骨髄腫を中心に2015
- Author(s)
  梅津知宏、大屋敷純子、大屋敷一馬
- Journal Title
  
  血液内科
  
  Volume: 71(3) Pages: 396-400
- Data Source
  KAKENHI-PROJECT-15H04303
[Journal Article] エクソソームと腫瘍血管2015
- Author(s)
  梅津知宏、大屋敷純子
- Journal Title
  
  血管医学
  
  Volume: 16(2) Pages: 19-24
- Data Source
  KAKENHI-PROJECT-15K06841
[Journal Article] Downregulated microRNA-148b in circulating PBMCs in chronic myeloid leukemia patients with undetectable minimal residual disease: a possible biomarker to discontinue imatinib safely.2014
- Author(s)
  Ohyashiki JH, Ohtsuki K, Mizoguchi I, Yoshimoto T, Katagiri S, Umezu T, Ohyashiki K.
- Journal Title
  
  Drug Des Devel Ther.
  
  Volume: 8 Pages: 1151-1159
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24501344
[Journal Article] Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1.2014
- Author(s)
  Umezu T, Tadokoro H, Azuma K, Yoshizawa S, Ohyashiki K, Ohyashiki JH.
- Journal Title
  
  Blood
  
  Volume: 124(25) Issue: 25 Pages: 3748-3757
- DOI
  10.1182/blood-2014-05-576116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25830089
[Journal Article] Constitutive activation of the ATM/BRCA1 pathway prevents DNA damage-induced apoptosis in 5-azacytidine-resistant cell lines.2014
- Author(s)
  Imanishi S, Umezu T, Ohtsuki K, Kobayashi C, Ohyashiki K, Ohyashiki JH.
- Journal Title
  
  Biochem Pharmacol.
  
  Volume: 89 Issue: 3 Pages: 361-369
- DOI
  10.1016/j.bcp.2014.03.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501344
[Journal Article] Down-regulated microRNA-148b in circulating PBMCs in chronic myeloid leukemia patients with undetectable minimal residual disease: A possible molecular classifier to stop imatinib safely.2014
- Author(s)
  Ohyashiki, J. H., Ohtsuki, K., Mizoguchi, I., Yoshimoto, T., Katagiri, S., Umezu, T., and Ohyashiki, K.
- Journal Title
  
  Drug Des. Devel. Ther.
  
  Volume: 8 Pages: 1151-1159
- DOI
  10.2147/dddt.s66812
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24370058, KAKENHI-PROJECT-24790091, KAKENHI-PUBLICLY-25118727, KAKENHI-PROJECT-25830089
[Journal Article] Exosomes derived from hypoxic leukemia cells enhance tube formation in endothelial cells.2013
- Author(s)
  Tadokoro H, Umezu T, Ohyashiki K, Hirano T, and Ohyashiki JH.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 288 Issue: 48 Pages: 34343-34351
- DOI
  10.1074/jbc.m113.480822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501344, KAKENHI-PROJECT-25830089
[Journal Article] Clinical relevance of plasma miR-106b levels in patients with chronic obstructive pulmonary disease2013
- Author(s)
  Soeda S, Ohyashiki JH, Ohtsuki K, Umezu T, Setoguchi Y, Ohyashiki K
- Journal Title
  
  Int J Mol Med.
  
  Volume: 31(3) Issue: 3 Pages: 533-539
- DOI
  10.3892/ijmm.2013.1251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25830089
[Journal Article] Leukemia cell to endothelial cell communication via exosomal miRNAs2013
- Author(s)
  Umezu T, Ohyashiki K, Kuroda M, Ohyashiki JH
- Journal Title
  
  Oncogene
  
  Volume: 32(22) Issue: 22 Pages: 2747-55
- DOI
  10.1038/onc.2012.295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23659626, KAKENHI-PROJECT-25830089
[Journal Article] Downregulated plasma miR-92a levels have clinical impact on multiple myeloma and related disorders.2012
- Author(s)
  Yoshizawa S, Ohyashiki JH, Ohyashiki M, Umezu T, Suzuki K, Inagaki A, Iida S, Ohyashiki K.
- Journal Title
  
  Blood Cancer J.
  
  Volume: 2(1) Issue: 1 Pages: e53-e53
- DOI
  10.1038/bcj.2011.51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701087, KAKENHI-PROJECT-23701088
[Journal Article] The C allele of JAK2 rs4495487 is an additional candidate locus that contributes to myeloproliferative neoplasm predisposition in the Japanese population.2012
- Author(s)
  Ohyashiki JH, Yoneta M, Hisatomi H, Iwabuchi T, Umezu T, Ohyashiki K.
- Journal Title
  
  BMC Med Genet.
  
  Volume: 13 Issue: 1 Pages: 6-6
- DOI
  10.1186/1471-2350-13-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701087
[Journal Article] Non-random chromosomal deletion clustering at 20q in Waldenstrom macroglobulinemia2011
- Author(s)
  Kitahara T, Umezu T, Ando K, Kodama A, Ohyashiki JH, Ohyashiki K
- Journal Title
  
  Hematology
  
  Volume: 16(3) Issue: 3 Pages: 139-42
- DOI
  10.1179/102453311x12953015767338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701087
[Journal Article] Detection method for quantifying global DNA methylation by fluorescence correlation spectroscopy2011
- Author(s)
  Umezu T, Ohyashiki K, Ohyashiki JH
- Journal Title
  
  Anal Biochem
  
  Volume: 415(2) Issue: 2 Pages: 145-50
- DOI
  10.1016/j.ab.2011.04.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701087
[Journal Article] Clinical impact of down-regulated plasma miR-92a levels in non-Hodgkin's lymphoma.2011
- Author(s)
  Ohyashiki K, Umezu T, Yoshizawa S, Ito Y, Ohyashiki M, Kawashima H, Tanaka M, Kuroda M, Ohyashiki JH.
- Journal Title
  
  PLoS One
  
  Volume: 6(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701087
[Journal Article] Non-random chromosomal deletion clustering at 20q in Waldenström macroglobulinemia.2011
- Author(s)
  Kitahara T, Umezu T, Ando K, Kodama A, Ohyashiki JH, Ohyashiki K.
- Journal Title
  
  Hematology.
  
  Volume: 16(3) Pages: 139-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701087
[Journal Article] Clinical impact of down-regulated plasma miR-92a levels in non-Hodgkin's lymphoma2011
- Author(s)
  Ohyashiki K, Umezu T, Yoshizawa S, Ito Y, Ohyashiki M, Kawashima H, Tanaka M, Kuroda M, Ohyashiki JH
- Journal Title
  
  PLoS One
  
  Volume: 6(2) Issue: 2 Pages: 16408-16408
- DOI
  10.1371/journal.pone.0016408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659626, KAKENHI-PROJECT-23701087
[Journal Article] Follistatin-like-1, a diffusible mesenchymal factor determines the fate of epithelium.2010
- Author(s)
  Umezu T., Yamanouchi H., Iida Y., Miura M., Tomooka Y.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 107(10)
  
  Pages: 4601-4606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570062
[Journal Article] Reconstruction of oviduct and demonstration of epithelial fate determination in mice.2010
- Author(s)
  Yamanouchi H., Umezu T., Tomooka Y.
- Journal Title
  
  Biol. Reprod 82(3)
  
  Pages: 528-533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570062
[Journal Article] Follistatin-like-1, a diffusible mesenchymal factor determines the fate of epithelium2010
- Author(s)
  Umezu T., Yamanouchi H., Iida Y., Miura M., Tomooka Y.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA. 107(10)
  
  Pages: 4601-4606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570062
[Journal Article] Reconstruction of oviduct and demonstration of epithelial fate determination in mice2010
- Author(s)
  Yamanouchi H., Umezu T., Tomooka Y.
- Journal Title
  
  Biol.Reprod. 82(3)
  
  Pages: 528-533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570062
[Patent] がんの罹患の可能性の試験方法およびそれに用いる試験試薬2017
- Inventor(s)
  大屋敷純子、梅津知宏
- Industrial Property Rights Holder
  学校法人東京医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-083898
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16K07183
[Patent] 1分子蛍光分析法による DNA メチル化度の決定方法2010
- Inventor(s)
  大屋敷純子・梅津知宏
- Industrial Property Rights Holder
  大屋敷一馬
- Industrial Property Number
  2010-167412
- Filing Date
  2010-07-26
- Data Source
  KAKENHI-PROJECT-23701087
[Presentation] Edible plant-derived nanovesicles to systemic deliver nucleic acid medicine for oral administration2024
- Author(s)
  Tomohiro Umezu, Mamoru Yanagimachi, Masakatsu Takanashi, Yoshiki Murakami, Masahiko Kuroda.
- Organizer
  ISEV2024（第13回国際細胞外小胞学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02706
[Presentation] がんにおけるパッセンジャー変異の意義と臨床応用2024
- Author(s)
  黒田雅彦、梅津知宏
- Organizer
  第8回Liquid Biopsy研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02706
[Presentation] Analysis of Mutation Signatures Involved in Colorectal Cancer Prognosis2024
- Author(s)
  Tomohiro Umezu, Akira Saito, Masahiko Kuroda
- Organizer
  第112回日本病理学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07133
[Presentation] Identification and biological significance of de novo mutational signatures in cfDNA derived from lung cancer patients2024
- Author(s)
  Tomohiro Umezu, Yujin Kudoh, Yoshihisa Shimada, Tatsuo Ohira, Yoshiki Murakami, Norihiko Ikeda, Masahiko Kuroda
- Organizer
  第8回Liquid biopsy研究会
- Data Source
  KAKENHI-PROJECT-21K07133
[Presentation] 大腸癌予後に関与するMutation Signatureの解析2023
- Author(s)
  梅津知宏、齋藤彰、黒田雅彦
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02706
[Presentation] リキッドバイオプシーを用いたがんゲノム医療の新しい展開ーパッセンジャー変異の意義と臨床応用ー2023
- Author(s)
  梅津知宏、黒田雅彦
- Organizer
  第131回東京脳腫瘍研究会
- Data Source
  KAKENHI-PROJECT-21K07133
[Presentation] Circulating miRNA analysis of hepatocellular carcinoma induced by chronic liver disease C after clearance of HCV2023
- Author(s)
  Yoshiki Murakami, Tomohiro Umezu, Shogo Tanaka, Shoji Kubo, Masaru Enomoto, Akihiro Tamori, Takahiro Ochiya, Y-h Taguchi, Masahiko Kuroda
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07133
[Presentation] 肺癌患者由来cfDNAから検出されたde novo mutational signatureの同定と生物学的意義の解明2023
- Author(s)
  梅津知宏、工藤勇人、嶋田義久、大平達夫、村上善基、池田徳彦、黒田雅彦
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02706
[Presentation] 理解剖例における網羅的遺伝子検索を目指した核酸品質の検討-追加報告-2023
- Author(s)
  渡辺紀子、市村香代子、村上仁彦、中澤温子、梅津知宏、黒田雅彦
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21H02706
[Presentation] ファブリー病におけるGb3の細胞内動態と ERストレスについての検討2023
- Author(s)
  桐林和代, 梅津知宏, 稲垣夏子, 黒田雅彦
- Organizer
  第47回日本遺伝カウンセリング学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02706
[Presentation] Edible plant-derived nanovesicles to systemic deliver nucleic acid medicine for oral administration2023
- Author(s)
  Tomohiro Umezu, Mamoru Yanagimachi, Masakatsu Takanashi, Yoshiki Murakami, Kenichi Nagamine, Shin Takeuchi, Masahiko Kuroda
- Organizer
  ASGCT 26th Annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02706
[Presentation] 大腸癌予後に関与するMutation Signatureの解析2023
- Author(s)
  梅津知宏、斎藤彰、黒田雅彦
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K07133
[Presentation] HCVをクリアランスしたのちに発癌した症例の末梢血miRNA解析2023
- Author(s)
  村上善基、梅津知宏、田中肖吾、久保正二、榎本　大、田守昭博、落谷孝広、田口善弘、黒田雅彦
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02706
[Presentation] Identification and biological significance of de novo mutational signatures in cfDNA derived from lung patients2023
- Author(s)
  Tomohiro Umezu, Yujin Kudoh, Yoshihisa Shimada, Tatsuo Ohira, Yoshiki Murakami, Norihiko Ikeda, Masahiko Kuroda
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07133
[Presentation] Cell-free DNAから前癌病変に特徴的なmutational signatureの同定とリキッドバイオプシーへの応用2022
- Author(s)
  梅津知宏, 工藤良平, 村上善基, 大野慎一郎, 工藤勇人, 池田徳彦, 黒田雅彦
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07133
[Presentation] 正常細胞および腫瘍細胞のCell-free DNAの産生メカニズムの解明とLiquid biopsyへの応用2022
- Author(s)
  梅津知宏, 黒田雅彦
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K07133
[Presentation] Integration of AI-based histopathology and genomic mutation analysis2022
- Author(s)
  Akira Saito, Tomohiro Umezu, Masahiko Kuroda
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02706
[Presentation] エクソソーム中miRNAによる潜在性結核診断法の開発2022
- Author(s)
  村上善基, 梅津知宏, 中嶋弘一, 田口善弘, 黒田雅彦
- Organizer
  第9回日本細胞外小胞学会
- Data Source
  KAKENHI-PROJECT-21K07133
[Presentation] AIによる病理組織形態解析とゲノム変異解析の融合2022
- Author(s)
  齋藤彰, 梅津知宏, 黒田雅彦
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07133
[Presentation] アセロラ果汁由来小胞を担体とした薬物脳内デリバリーの試み2022
- Author(s)
  梅津知宏, 樋口恒星, 高梨正勝, 大野慎一郎, 原田裕一郎, 黒田雅彦
- Organizer
  第9回日本細胞外小胞学会
- Data Source
  KAKENHI-PROJECT-21K07133
[Presentation] 血中遊離DNAからのmutational signatureの検出と非侵襲性早期診断システムの開発2021
- Author(s)
  梅津　知宏、斎藤　彰、工藤　勇人、嶋田　善久、大平　達夫、池田　徳彦、黒田　雅彦
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K07133
[Presentation] 経口投与によるアセロラ果汁由来小胞のDDS担体としての有用性2021
- Author(s)
  梅津　知宏、高梨　正勝、大野　慎一郎、原田　裕一郎、黒田　雅彦
- Organizer
  The 8th Annual Meeting of the Japanese Society for Extracellular Vesicles
- Data Source
  KAKENHI-PROJECT-21K07133
[Presentation] 血中遊離DNAにおけるゲノムsignatureの検出および早期診断・再発リスク予測システムの開発2021
- Author(s)
  梅津　知宏、工藤　勇人、嶋田　善久、大平　達夫、池田　徳彦、黒田　雅彦
- Organizer
  第62回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07133
[Presentation] 経口投与によるアセロラ果汁由来小胞のDDS担体としての有用性2021
- Author(s)
  梅津知宏、髙梨正勝、大野慎一郎、原田裕一郎、黒田雅彦
- Organizer
  第8回日本細胞外小胞学会 (JSEV)
- Data Source
  KAKENHI-PROJECT-21H02706
[Presentation] Analysis of miRNA expression in liver and blood in precancerous state of hepatocellular carcinoma2021
- Author(s)
  Tomohiro Umezu, Yoshiki Murakami, Masahiko Kuroda
- Organizer
  The 80th Annual Meeting of the Japan Cancer Association
- Data Source
  KAKENHI-PROJECT-21K07133
[Presentation] Aging-associated aberrant microRNA expression plays a role in hepatocarcinogenesis2020
- Author(s)
  Tomohiro Umezu, Akihiro Tamori, Takahiro Ochiya, Masahiko Kuroda, Yoshiki Murakami
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07244
[Presentation] アセロラ果汁由来小胞を用いたドラッグデリバリーシステムの開発2020
- Author(s)
  梅津知宏、高梨正勝、大野慎一郎、村上善基、黒田雅彦
- Organizer
  第7回日本細胞外小胞学会
- Data Source
  KAKENHI-PROJECT-18K07244
[Presentation] Acerola derived exosome-like nanovesicles enhances the repair of ultraviolet B-induced DNA damage in cultured skin fibroblasts2020
- Author(s)
  Tomohiro Umezu, Kazuma Ohyashiki, Masahiko Kuroda.
- Organizer
  ANNUAL MEETING ISEV2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07244
[Presentation] アセロラ果汁由来小胞の機能解析とその有用性に関する研究2019
- Author(s)
  梅津　知宏、高梨正勝、大野慎一郎、黒田雅彦
- Organizer
  第6回日本細胞外小胞学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07244
[Presentation] がん間質細胞由来エクソソームはNK細胞の抗腫瘍効果を抑制する2019
- Author(s)
  梅津　知宏、大屋敷一馬、黒田雅彦．
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07244
[Presentation] 肺がん患者由来エクソソームmiRNAを用いた診断バイオマーカーの探索2019
- Author(s)
  梅津　知宏、高梨　正勝、斎藤　彰、工藤　勇人、嶋田　善久、大平　達夫、池田　徳彦、黒田　雅彦
- Organizer
  第60回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07244
[Presentation] Extravellular vesicles derived from bone marrow stromal cells promote evasion of multiple myeloma cells from NK cell anti-tumor activity2019
- Author(s)
  Tomohiro Umezu, Kazuma Ohyashiki, Masahiko Kuroda.
- Organizer
  ANNUAL MEETING ISEV 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07244
[Presentation] The role of extracellular vesicle-mediated miR-10a transfer in bone marrow microenvironment of patients with multiple myeloma.2018
- Author(s)
  Umezu T, Ohyashiki K, Ohyashiki JH
- Organizer
  International Society for Extracellular Vesicles 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07244
[Presentation] Extracellular vesicle-mediated miRNA transfer enhances growth and survival of multiple myeloma.2018
- Author(s)
  Umezu T, Imanishi S, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07244
[Presentation] Characterization of novel bona marrow stromal cells from healthy donors.2018
- Author(s)
  Umezu T, Gladkova N, Imanishi S, Ohyashiki K, Ohyashiki JH
- Organizer
  第36回ヒト細胞学会学術集会
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Extracellular vesicle-mediated miRNA transfer enhances growth and survival of multiple myeloma.2018
- Author(s)
  Umezu T, Imanishi, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Bone marrow mesenchymal stromal cells from healthy donors secrete anti-angiogenic EVs as well as soluble factors having growth inhibitory effect in MM.2018
- Author(s)
  Umezu T, Imanishi S, Gladkova N, Ohyashiki K, Ohyashiki JH
- Organizer
  European Hematology Association 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07244
[Presentation] Lineage-specific RUNX2uper-enhncer activates MYC via a chromosomal translocation and promotes the BPDCN.2018
- Author(s)
  Kubota S, Umezu T, Iwama A, Ohyashiki K, Osato M, Sashida G
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07244
[Presentation] 5-azacytidine targets chromatin regulation through piRNA pathway.2018
- Author(s)
  Imanishi S, Azuma K, Umezu T, Kawana C, Ohyashiki K, Ohyashiki JH
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] The role of extracellular vesicle-mediated miR-10a transfer in bone marrow microenvironment of patients with multiple myeloma.2018
- Author(s)
  Umezu T, Ohyashiki K, Ohyashiki JH
- Organizer
  International Society for Extracellular Vesicles 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Bone marrow mesenchymal stromal cells from healthy donors secrete anti-angiogenic EVs as well as soluble factors having growth inhibitory effect in MM.2018
- Author(s)
  Umezu T, Imanishi S, Gladkova N*, Ohyashiki K, Ohyashiki JH
- Organizer
  European Hematology Association 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Sequential analysis of clonal evolution by targeted deep sequencing in therapy-related myeloid neoplasm.2018
- Author(s)
  Katagiri S, Azuma K, Saito Y, Yoshizawa S, Akahane D, Fujimoto H, Ito Y, Umezu T, Ohyashiki JH, Ohyashiki K
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] 5-azacytidine targets chromatin regulation through piRNA pathway.2018
- Author(s)
  Imanishi S, Azuma K, Umezu T, Kawana C, Ohyashiki K, Ohyashiki JH
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07244
[Presentation] ステロイド抵抗性急性GVHDに対するヒト骨髄由来間葉系幹細胞治療2018
- Author(s)
  片桐誠一朗、吉澤成一郎、梅津知宏、齋藤優、勝呂多光子、赤羽大悟、田中裕子、古屋奈穂子、藤本博昭、後藤守孝、大屋敷一馬
- Organizer
  免疫アレルギー研究会
- Data Source
  KAKENHI-PROJECT-18K07244
[Presentation] Characterization of novel bona marrow stromal cells from healthy donors.2018
- Author(s)
  Umezu T, Gladkova N, Imanishi S, Ohyashiki K, Ohyashiki JH
- Organizer
  第36回ヒト細胞学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07244
[Presentation] A statistical integrative analysis method for small size expression data of microRNAs and genes.2017
- Author(s)
  Ohki T, Umezu T, Ohyahsiki JH, Fukuoka Y
- Organizer
  39th International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE EMBC2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] A statistical integrative analysis method for small size expression data of microRNAs and genes.2017
- Author(s)
  Ohki T, Umezu T, Ohyahsiki JH, Fukuoka Y
- Organizer
  39th International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE EMBC2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Teriflunomide restores 5-azacytidine sensitivity via activation of pyrimidine salvage in 5-azacytidine-resistant leukemia cells2017
- Author(s)
  Imanishi S, Takahashi R, Katagiri S, Umezu T, Kobayashi C, Ohyashiki K, Ohyashiki JH
- Organizer
  The 14th International Symposium on Myelodysplastic Syndromes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Extracellular vesicles (EVs) released by bone marrow stromal cells show a distinct miRNA profile in high-risk MDS patients.2017
- Author(s)
  Ohyashiki K, Saitoh Y, Imanishi S, Umezu T, Yoshizawa S, Asano M, Fujimoto H, Akahane D, Kobayashi C, Ohyashiki JH:
- Organizer
  The 14th International Symposium on Myelodysplastic Syndromes (MDS2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] RUNX2 super enhancer promotes the development of blastic plasmacytoid dendritic cell neoplasm. 21th RUNX meeting2017
- Author(s)
  Sashida G, Kubota S, Tokunaga K, Oshima M, Umezu T, Kanai A, Tan KT, Yang H, Iwanaga E, Asou N, Maeda T, Iwama A, Ohyashiki K, Osato M
- Organizer
  21th RUNX meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Inhibition of extracellular vesicle secretion induces apoptosis of bone marrow stromal cells: Towards soil-targeted therapy in multiple myeloma.2017
- Author(s)
  Umezu T, Imanishi S, Yoshizawa S, Ohyahsiki K, Ohyashiki JH
- Organizer
  22nd Congress of European Hematology Association (EHA2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Replenishing exosomes from older bone marrow stromal cells by miR-340 inhibits myeloma-related angiogenesis.2017
- Author(s)
  Umezu T, Imanishi S, Azuma K, Yoshizawa S, Ohyashiki K, Ohyashiki JH:
- Organizer
  The Royal Society Scientific Meeting 2017 “Extracellular vesicles and the tumor microenvironment”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] miRNA profiling of circulating extracellular vesicles in CML patients with musculoskeletal pain associated with discontinuation of tyrosine kinase inhibitors.2017
- Author(s)
  Ohyashiki K, Asano M, Umezu T, Katagiri S, Kobayashi C, Tauchi T, Gotoh M, Ando K, Okabe S, Ohyashiki JH
- Organizer
  22nd Congress of European Hematology Association (EHA2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Extracellular vesicles (EVs) released by bone marrow stromal cells show a distinct miRNA profile in high-risk MDS patients.2017
- Author(s)
  Ohyashiki K, Saitoh Y, Imanishi S, Umezu T, Yoshizawa S, Asano M, Fujimoto H, Akahane D, Kobayashi C, Ohyashiki JH
- Organizer
  The 14th International Symposium on Myelodysplastic Syndromes (MDS2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Inhibition of extracellular vesicle secretion induces apoptosis of bone marrow stroma cells2017
- Author(s)
  Umezu T, Imanishi S, Yoshizawa Sm Ohyashiki K, Ohyashiki JH
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Inhibition of extracellular vesicle secretion induces apoptosis of bone marrow stromal cells: Towards soil-targeted therapy in multiple myeloma.2017
- Author(s)
  Umezu T, Imanishi S, Yoshizawa S, Ohyahsiki K, Ohyashiki JH:
- Organizer
  22nd Congress of European Hematology Association (EHA2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Inhibition of extracellular vesicle secretion induces apoptosis of bone marrow stromal cells derived from multiple myeloma patients.2017
- Author(s)
  Umezu T, Imanishi S, Azuma K, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  The 76th Annual Meeting of Japanese Cancer Association (JCA2017)
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Inhibition of extracellular vesicle secretion induces apoptosis of bone marrow stromal cells: Towards soil-targeted therapy in multiple myeloma2017
- Author(s)
  Umezu T, Imanishi S, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  22th European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] A role of exosomal miR-10a in bone marrow stromal cells obtained from patients with multiple myeloma.2017
- Author(s)
  Umezu T, Imanishi S, Yoshizawa S, Ohyashiki K, Ohyashiki JH:
- Organizer
  6th Annual Meeting of International Society for Extracellular Vesicles (ISEV2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Extracellular vesicles (EVs) released by bone marrow stromal cells show a distinct miRNA profiling in high-risk MDS patients2017
- Author(s)
  Ohyashiki K, Saitoh Y, Imanishi S, Umezu T, Yoshizawa S, Asano M, Fujimoto H, Akahane D, Kobayashi C, Ohyashiki JH
- Organizer
  The 14th International Symposium on Myelodysplastic Syndromes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Cross-talk mediated by bone marrow stromal cells-derived extracellular vesicles.2017
- Author(s)
  Umezu T, Imanishi S, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  Tokyo Medical University, Institute of Medical Science, 1st International Symposium “Role of Aging and Cancer”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Inhibition of extracellular vesicle secretion induces apoptosis of bone marrow stromal cells derived from multiple myeloma patients.2017
- Author(s)
  Umezu T, Imanishi S, Azuma K, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  The 76th Annual Meeting of Japanese Cancer Association (JCA2017)
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] A role of exosomal miR-10a in bone marrow stromal cells obtained from patients with multiple myeloma.2017
- Author(s)
  Umezu T, Imanishi S, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  6th Annual Meeting of International Society for Extracellular Vesicles (ISEV2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Cross-talk mediated by bone marrow stromal cells-derived extracellular vesicles.2017
- Author(s)
  Umezu T, Imanishi S, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  Tokyo Medical University, Institute of Medical Science, 1st International Symposium “Role of Aging and Cancer”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Teriflunomide restores 5-azacytidine sensitivity via activation of pyrimidine salvage in 5-azacytidine-resistant leukemia cells.2017
- Author(s)
  Imanishi S, Takahashi R, Katagiri S, Umezu T, Yoshizawa S, Kobayashi C, Ohyashiki K, Ohyashiki JH:
- Organizer
  The 14th International Symposium on Myelodysplastic Syndromes (MDS2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Altered exosomal miRNA expression of late onset acute graft-versus-host disease in allogenic hematopoietic stem cell transplantation.2017
- Author(s)
  Yoshizawa S, Umezu T, Saitoh Y, Gotoh M, Akahane D, Kobayashi C, Ohyashiki JH, Ohyashiki K
- Organizer
  The 79th Annual Meeting of Japanese Society of Hematology (JSH2017)
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Telomeric repeat-containing RNA (TERRA) in MDS: Utility of cell-free TERRA packaged in extracellular vesicles.2017
- Author(s)
  Ohyashiki JH, Umezu T, Kobayashi C, Imanishi S, Asano M, Ohyashiki K:
- Organizer
  The 14th International Symposium on Myelodysplastic Syndromes (MDS2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Altered exosomal miRNA expression of late onset acute graft-versus-host disease in allogenic hematopoietic stem cell transplantation.2017
- Author(s)
  Yoshizawa S, Umezu T, Saitoh Y, Gotoh M, Akahane D, Kobayashi C, Ohyashiki JH, Ohyashiki K
- Organizer
  The 79th Annual Meeting of Japanese Society of Hematology (JSH2017)
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Replenishing exosomes from older bone marrow stromal cells by miR-340 inhibits myeloma-related angiogenesis2017
- Author(s)
  Umezu T, Imanishi S, Azuma K, Kobayashi C, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  RoyalSociety2017 「Extracellular cvesicles and tumor microenvironment」
- Place of Presentation
  London
- Year and Date
  2017-01-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] miRNA profiling of circulating extracellular vesicles in CML patients with musculoskeletal pain associated with discontinuation of tyrosine kinase inhibitors.2017
- Author(s)
  Ohyashiki K, Asano M, Umezu T, Katagiri S, Kobayashi C, Tauchi T, Gotoh M, Ando K, Okabe S, Ohyashiki JH:
- Organizer
  22nd Congress of European Hematology Association (EHA2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] miRMA profiling of circulating extracellular vesicles in CML patients with musculoskeletal pain associated with discontinuation of tyrosine kinase inhibitors2017
- Author(s)
  Ohyashiki K, Asano M, Umezu T, Katagiri S, Kobayashi C, Tauchi T, Gotoh M, Ando K, Okabe S, Ohyashiki K
- Organizer
  22th European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Clinical relevance of plasma miR-215 level in CML patients treated with imatinib2016
- Author(s)
  Katagiri S, Umezu T, Kobayashi C, Azuma K, Tauchi T, Okabe S, Ohyashiki JH, Ohyashiki K
- Organizer
  7th JSH International Symposium 2016
- Place of Presentation
  Awaji
- Year and Date
  2016-05-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Anti-angiogenic effect of normal bone marrow stromal cell-derived exosomes rejuvenated by miR-3402016
- Author(s)
  Umezu T, Imanishi S, Azuma K, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  The 78th Annual Meeting of Japanese Society of Hematology (JSH2016)
- Place of Presentation
  横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] 慢性骨髄性白血病におけるチロシンキナーゼ阻害薬中止後の筋骨格痛ではエクソソームmiR-140-3pの上昇がみられる2016
- Author(s)
  浅野倫代、梅津知宏、片桐誠一朗、小林千晶、田内哲三、岡部聖一、大屋敷純子、大屋敷一馬
- Organizer
  第178回東京医科大学医学会総会
- Place of Presentation
  東京
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] 骨髄間質細胞が放出するエクソソーム内加齢関連miRNAの同定と機能解析2016
- Author(s)
  関野知聖、梅津知宏、吉澤成一郎、大屋敷一馬、大屋敷純子
- Organizer
  第178回東京医科大学医学会総会
- Place of Presentation
  東京
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-26860373
[Presentation] 多発性骨髄腫における骨髄内微小環境でのエクソソームの役割2016
- Author(s)
  梅津知宏、大屋敷一馬、大屋敷純子
- Organizer
  第41回日本骨髄腫学会学術集会
- Place of Presentation
  徳島
- Year and Date
  2016-05-28
- Invited
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Clonal evolution in AML which relapsed 15 years after BMT2016
- Author(s)
  Katagiri S, Azuma K, Umezu T, Akahane D, Wataya Y, Yoshida K, Makishima H, Ogawa S, Ohyashiki JH, Ohyashiki K
- Organizer
  第78回日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] アザシチジン耐性白血病細胞におけるヒストン化学修飾の役割の解明2016
- Author(s)
  髙橋諒子、今西哲、梅津知宏、小林千晶、大屋敷一馬、大屋敷純子
- Organizer
  第178回東京医科大学医学会総会
- Place of Presentation
  東京
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Down-regulation of plasma miR-215 in chronic myeloid leukemia patients with successful imatinib discontinuation.2016
- Author(s)
  Ohyashiki K, Umezu T, Katagiri S, Kobayashi C, Azuma K, Tauchi T, Okabe S, Fukuoka Y, Ohyashiki JH
- Organizer
  10th AACR-JCA Joint Conference
- Place of Presentation
  Maui, Hawaii
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Anti-angiogenic effect of normal bone marrow stromal cell-derived exosomes rejuvenated by miR-340.2016
- Author(s)
  Umezu T, Imanishi S, Azuma K, Yoshizawa S, Ohyashiki K, Ohyashiki J
- Organizer
  The 78th Annual Meeting of Japanese Society of Hematology
- Place of Presentation
  Yokohama
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26860373
[Presentation] がん環境を標的とした治療戦略：骨髄間質細胞由来エクソソームおよびその内包型miRNAの役割2016
- Author(s)
  梅津知宏、大屋敷一馬、大屋敷純子
- Organizer
  第8回日本RNAi研究会・第3回日本細胞外小胞学会
- Place of Presentation
  広島
- Year and Date
  2016-08-31
- Invited
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Toward exosome-based cancer therapy: rejuvenation of exosomes derived from normal bone stroma cells2016
- Author(s)
  Umezu T, Imanishi S, Azuma K, Kobayashi C, Ohyashiki K, Ohyashiki JH
- Organizer
  ISEV 2016
- Place of Presentation
  Rotterdam
- Year and Date
  2016-05-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Mutation analysis of bone marrow stromal cells derived from AML and MDS2016
- Author(s)
  Azuma K, Umezu T, Imanishi S, Asano M, Yoshizawa S, Katagiri S, Ohyashiki K, Ohyashiki JH
- Organizer
  第78回日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Towards exosome-based cancer therapy: rejuvenation of exosomes derived from normal bone marrow stromal cells2016
- Author(s)
  Umezu T, Imanishi S, Azuma K, Kobayashi C, Ohyashiki K, Ohyashiki JH
- Organizer
  ISEV2016 (5th Annual Meeting of International Society for Extracellular Vesicles)
- Place of Presentation
  Rotterdam
- Year and Date
  2016-05-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] 多発性骨髄腫における骨髄内微小環境でのエクソソームの役割2016
- Author(s)
  梅津知宏、大屋敷一馬、大屋敷純子
- Organizer
  第19回癌と骨病変研究会
- Place of Presentation
  東京
- Year and Date
  2016-11-11
- Invited
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Bone marrow stromal cells from young healthy donors secrete exosomes that inhibit in vivo angiogenesis in multiple myeloma.2016
- Author(s)
  Umezu T, Imanishi S, Azuma K, Kobayashi C, Ohyashiki K, Ohyashiki JH
- Organizer
  10th AACR-JCA Joint Conference
- Place of Presentation
  Maui, Hawaii
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] 骨髄間質細胞が放出するエクソソーム内加齢関連miRNAの同定と機能解析2016
- Author(s)
  関野知聖、梅津知宏、吉澤成一郎、大屋敷一馬、大屋敷純子
- Organizer
  第178回東京医科大学医学会総会
- Place of Presentation
  東京
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Clinical relevance of plasma miR-215 level in CML patients treated with imatinib2016
- Author(s)
  Katagiri S, Umezu T, Kobayashi C, Azuma K, Tauchi T, Okabe S, Ohyashiki JH, Ohyashiki K
- Organizer
  7th JSH International Symposium
- Place of Presentation
  Awajishima
- Year and Date
  2016-05-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Down-regulation of plasma miR-215 in chronic myeloid leukemia patients with successful imatinib discontinuation.2016
- Author(s)
  Ohyashiki K, Umezu T, Katagiri S, Kobayashi C, Azuma K, Tauchi T, Okabe S, Fukuoka Y, Ohyashiki JH
- Organizer
  10th AACR-JCA Joint Conference
- Place of Presentation
  Maui, Hawaii
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Bone marrow stromal cells from young healthy donors secrete exosomes that inhibit in vivo angiogenesis in multiple myeloma.2016
- Author(s)
  Umezu T, Imanishi S, Azuma K, Kobayashi C, Ohyashiki K, Ohyashiki JH
- Organizer
  10th AACR-JCA Joint Conference
- Place of Presentation
  Maui, Hawaii
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Mutation analysis of bone marrow stromal cells derived from AML and MDS.2016
- Author(s)
  Azuma K, Umezu T, Imanishi S, Asano M, Yoshizawa S, Katagiri S, Ohyashiki K, Ohyashiki JH
- Organizer
  The 78th Annual Meeting of Japanese Society of Hematology
- Place of Presentation
  Yokohama
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26860373
[Presentation] miRNAとmRNAの統合解析における発現変化の閾値の最適化2016
- Author(s)
  大木拓也、福岡　豊、大屋敷純子、梅津知宏
- Organizer
  第55回日本生体医工学会大会
- Place of Presentation
  富山
- Year and Date
  2016-04-26
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Anti-angiogenic effect of normal bone marrow stromal cell-derived exosomes rejuvenated by miR-340.2016
- Author(s)
  Umezu T, Imanishi S, Azuma K, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  The 78th Annual Meeting of Japanese Society of Hematology
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Exosome-based therapeutic approach using exosomal miRNAs derived from bone marrow mesenchymal stromal cells2015
- Author(s)
  Umezu T, Imanishi S, Azuma K, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Bone marrow mesenchymal stromal cells from healthy donors secrete exosomes that inhibit in vivo tumor growth and angiogenesis in multiple myeloma.2015
- Author(s)
  Umezu T, Imanishi S, Azuma K, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  20th Congress of European Hematology Association (EHA)
- Place of Presentation
  Vienna, Austria
- Year and Date
  2015-06-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] The genome-wide DNA methylation status as a predictor of 5-azacytidine in clinical responses.2015
- Author(s)
  Asao M, Kobayashi C, Umezu T, Ohyashiki K, Ohyashiki K
- Organizer
  6th JSH International symposium
- Place of Presentation
  軽井沢
- Year and Date
  2015-05-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Age-related alterations in exosomal miRNAs derived from bone marrow mesenchymal stromal cells.2015
- Author(s)
  Umezu T, Imanishi S, Yoshizawa S, Saitoh Y, Yamamoto Y, Ohyashiki K, Ohyashiki JH
- Organizer
  6th JSH International Symposium 2015
- Place of Presentation
  軽井沢
- Year and Date
  2015-05-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Distinct exosomal miRNA expression of late onset graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.2015
- Author(s)
  Yoshizawa S, Umezu T, Saitoh Y, Gotoh M, Akahane D, Kobayashi C, Ohyashiki JH, Ohyashiki K
- Organizer
  20th Congress of European Hematology Association (EHA)
- Place of Presentation
  Vienna, Austria
- Year and Date
  2015-06-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860373
[Presentation] Distinct exosomal miRNA expression of late onset graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.2015
- Author(s)
  Yoshizawa S, Umezu T, Saitoh Y, Gotoh M, Akahane D, Kobayashi C, Ohyashiki JH, Ohyashiki K
- Organizer
  20th Congress of European Hematology Association (EHA)
- Place of Presentation
  Vienna, Austria
- Year and Date
  2015-06-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Exosomal miRNA signature of bone marrow mesenchymal stromal cells derived from MDS patients.2015
- Author(s)
  Saitoh Y, Imanishi S, Umezu T, Yoshizawa S, Asano M, Fujimoto H, Akahane D, Yamamoto Y, Kobayashi C, Ohyashiki JH, Ohyashiki K
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Exosomal miRNA signature of late onset acute GVHD in allogeneic HSCT.2015
- Author(s)
  Yoshizawa S, Umezu T, Ohyashiki JH, Ohyashiki K
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Exosome-based therapeutic approach using exosomal miRNAs derived from bone marrow mesenchymal stromal cells.2015
- Author(s)
  Umezu T, Imanishi S, Azuma K, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Age-related alterations in exosomal miRNAs derived from bone marrow mesenchymal stromal cells.2015
- Author(s)
  Umezu T, Imanishi S, Yoshizawa S, Saitoh Y, Yamamoto Y, Ohyashiki K, Ohyashiki JH
- Organizer
  6th JSH International Symposium 2015
- Place of Presentation
  軽井沢
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-26860373
[Presentation] Exosomal miRNA signature of bone marrow mesenchymal stromal cells derived from MDS patients.2015
- Author(s)
  Saitoh Y, Imanishi S, Umezu T, Yoshizawa S, Asano M, Fujimoto H, Akahane D, Yamamoto Y, Kobayashi C, Ohyashiki JH, Ohyashiki K
- Organizer
  第77回日本血液学会学術集会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Distinct exosomal miRNA expression of late onset graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.2015
- Author(s)
  Yoshizawa S, Umezu T, Ohyashiki JH, Ohyashiki K
- Organizer
  20th European Hematology Association Congress
- Place of Presentation
  Wien, Austria
- Year and Date
  2015-06-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Exosome-based therapeutic approach using exosomal miRNAs derived from bone marrow mesenchymal stromal cells.2015
- Author(s)
  Umezu T, Imanishi S, Azuma K, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26860373
[Presentation] Exosomal miRNA signature of late onset acute graft-versus-host disease in allogenic hematopoietic stem cell transplantation.2015
- Author(s)
  Yoshizawa S, Umezu T, Saitoh Y, Gotoh M, Akahane D, Kobayashi C, Ohyashiki JH, Ohyashiki K
- Organizer
  第77回日本血液学会学術集会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26860373
[Presentation] Leukemia cells under persistent hypoxia secrete exosomes enhancing angiogenesis in mice.2015
- Author(s)
  Ohyashiki K, Umezu T, Imanishi S, Ohyashiki JH
- Organizer
  ISEH 44th Annual Scientific Meeting
- Place of Presentation
  京都
- Year and Date
  2015-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Telomere repeat-containing RNA (TERRA), a possible epigenetic biomarker of DNA damage phenotype in 5-azacytidine-resistant leukemia cells2015
- Author(s)
  Kenko Azuma, Tomohiro Umezu, Satoshi Imanishi, Chiaki Kobayashi, Michiyo Asano, Seiichiro Katagiri, Daigo Akahane, Kazuma Ohyashiki, Junko H. Ohyashiki
- Organizer
  The 6th JSH International Symposium
- Place of Presentation
  軽井沢
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-24501344
[Presentation] Exosomal miRNA signature of bone marrow mesenchymal stromal cells derived from MDS patients.2015
- Author(s)
  Saitoh Y, Imanishi S, Umezu T, Yoshizawa S, Asano M, Fujimoto H, Akahane D, Yamamoto Y, Kobayashi C, Ohyashiki JH, Ohyashiki K
- Organizer
  第77回日本血液学会学術集会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26860373
[Presentation] Establishment and characterization of a novel chronic hypoxia-resistant multiple myeloma cell lines, IM-9-HR.2015
- Author(s)
  Azuma K, Takeuchi K, Umezu T, Ohyashiki K, Ohyashiki JH
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Bone marrow mesenchymal stromal cells from healthy donors secrete exosomes that inhit in vivo tumor growth and angiogenesis in multiple myeloma.2015
- Author(s)
  Umezu T, Ohyashiki K, Ohyashiki JH
- Organizer
  20th European Hematology Association Congress
- Place of Presentation
  Wien, Austria
- Year and Date
  2015-06-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Age-related alterations in exosomal miRNAs derived from bone marrow mesenchymal stromal cells.2015
- Author(s)
  Umezu T, Ohyashiki K, Ohyashiki JH
- Organizer
  6th JSH International symposium
- Place of Presentation
  軽井沢
- Year and Date
  2015-05-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Bone marrow mesenchymal stromal cells from healthy donors secrete exosomes that inhibit in vivo tumor growth and angiogenesis in multiple myeloma.2015
- Author(s)
  Umezu T, Imanishi S, Azuma K, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  20th Congress of European Hematology Association (EHA)
- Place of Presentation
  Vienna, Austria
- Year and Date
  2015-06-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860373
[Presentation] Exosomal miRNA signature of late onset acute graft-versus-host disease in allogenic hematopoietic stem cell transplantation.2015
- Author(s)
  Yoshizawa S, Umezu T, Saitoh Y, Gotoh M, Akahane D, Kobayashi C, Ohyashiki JH, Ohyashiki K
- Organizer
  第77回日本血液学会学術集会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K06841
[Presentation] Towards comprehensive understanding of the mechanism underlying resistance to 5-azacytidine2014
- Author(s)
  Imanishi S, Umezu T, Ohtsuki K, Kobayshi C, Ohyashiki K, Ohyashiki JH.
- Organizer
  5th JSH International Symposium, 2014
- Place of Presentation
  アクトシティ浜松、浜松、静岡
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-24501344
[Presentation] A possible role of DNA damage/repair in 5-azacytidine resistant leukemia cells.2013
- Author(s)
  Imanishi S, Umezu T, Ohtsuki K, Kobayashi C, Ohyashiki K, Ohyashiki JH
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24501344
[Presentation] A possible association between 5-azacytidine sensitivity and epigenetic modulation of telomere in human leukemia cells.2013
- Author(s)
  Ohyashiki JH, Umezu T, Kobayashi C, Imanishi S, Asano M, Ohyashiki K
- Organizer
  12th International Symposium on MDS syndrome
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-24501344
[Presentation] DNA methylated index of peripheral blood is a predictive marker for resistance to azacytidine in MDS patients. 12th International Symposium on MDS syndrome2013
- Author(s)
  Asano M, Ohyashiki JH, Umezu T, Kobayashi C, Fujimoto H, Gotoh M, Alahane D, Kitahara T, Yoshizawa S, Ito Y, Ohyashiki K.
- Organizer
  12th International Symposium on MDS syndrome
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-24501344
[Presentation] Involvement of pyrimidine metabolism pathway in 5’-azacytidine resistance.2013
- Author(s)
  Imanishi S, Umezu T, Kobayashi C, Ohyashiki K, Ohyashiki JH
- Organizer
  AACR Annual Meeting 2013
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-24501344
[Presentation] Hypoxia modulates tumor exosomes, which function as mediators of angiogenesis.2013
- Author(s)
  Umezu T
- Organizer
  AACR Annual Meeting 2013
- Place of Presentation
  Washington, DC, U. S. A.
- Data Source
  KAKENHI-PROJECT-25830089
[Presentation] Hypoxic myeloma cell modulates its microenvironment via exosomes2013
- Author(s)
  梅津　知宏
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25830089
[Presentation] 骨髄異形成症候群 (MDS)のDNAメチル化度の評価；Single Molecular Methylation Assay (SMMA)法の有用性2012
- Author(s)
  浅野倫代、大屋敷純子、梅津知宏、大槻和重、大屋敷一馬
- Organizer
  第6回日本エピジェネティクス研究会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23701087
[Presentation] Epigenetic aberration in leukocytes of patients with myelodysplastic syndrome2012
- Author(s)
  浅野倫代、大屋敷純子、梅津知宏、藤本博昭、後藤守孝、赤羽大悟、北原俊彦、吉澤成一郎、大屋敷一馬
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23701087
[Presentation] 骨髄異形成症候群におけるメチル化度測定による治療効果予測2012
- Author(s)
  浅野倫代、小林千晶、廣田綾子、梅津知宏、大屋敷一馬、大屋敷純子
- Organizer
  第170回東京医科大学医学会総会
- Place of Presentation
  東京
- Year and Date
  2012-11-17
- Data Source
  KAKENHI-PROJECT-23701087
[Presentation] 骨髄異形成症候群 (MDS)のDNA メチル化度の評価;Single Molecular Methylation Assay (SMMA)法の有用性2012
- Author(s)
  浅野倫代、大屋敷純子、梅津知宏、大槻和重、大屋敷一馬
- Organizer
  第6回日本エピジェネティクス研究会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23701087
[Presentation] Epigenetic aberration in leukocytes of patients with myelodysplastic syndrome.2012
- Author(s)
  浅野倫代、大屋敷純子、梅津知宏、藤本博昭、後藤守孝、赤羽大悟、北原俊彦、吉澤成一郎、大屋敷一馬
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23701087
[Presentation] DNA demethylation and up-regulation of telomere repeat-containing RNAs (TERRAs) in human leukemia cells.2012
- Author(s)
  大屋敷純子、梅津知宏、小林千晶、大屋敷一馬
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24501344
[Presentation] A Novel Global DNA Methylation Detection by Fluorescence Spectroscopy, and Possible Evaluation System of Demethylating Status for Myelodysplastic Patients.2011
- Author(s)
  Ohyashiki K, Umezu T, Ohyashiki JH
- Organizer
  11th MDS symposium
- Place of Presentation
  Edinburgh
- Data Source
  KAKENHI-PROJECT-23701087
[Presentation] 非ホジキンリンパ腫の血清 miR-92a レベルは免疫状態と関係し、再発予測因子となる2011
- Author(s)
  大屋敷倫代、梅津知宏、吉澤成一郎、大屋敷純子、大屋敷一馬
- Organizer
  リンパ網内系学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23701087
[Presentation] DNA demethylation induces up-regulation of telomere repeat-containing RNAs (TERRA) and down-regulation of telomerase activity in human leukemia cells.2011
- Author(s)
  Ohyashiki JH, Umezu T, Ohyashiki M, Ohtsuki T, Kobayashi C, Ohyashiki K
- Organizer
  2nd AACR conference on frontiers in basic cancer research
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-23701087
[Presentation] A Novel Global DNA Methylation Detection by Fluorescence Spectroscopy, and Possible Evaluation System of Demethylating Status for Myelodysplastic Patients2011
- Author(s)
  Ohyashiki K, Umezu T, Ohyashiki JH
- Organizer
  11th MDS symposium
- Place of Presentation
  Edinburgh
- Data Source
  KAKENHI-PROJECT-23701087
[Presentation] Exosomal miR-92a derived from leukemia cell enhances endothelial cell migration.2011
- Author(s)
  Umezu T, Ohyashiki JH, Yoshizawa S, Ohyashiki M, Ohyashiki K
- Organizer
  Keystone Symposia on MicroRNAs and Non-Coding RNAs and Cancer
- Place of Presentation
  Banff, Canada
- Data Source
  KAKENHI-PROJECT-23701087
[Presentation] 1 分子蛍光分析法によるDNA メチル化度の定量法の開発2011
- Author(s)
  大屋敷純子、梅津知宏、大屋敷倫代、小林千晶、大屋敷一馬
- Organizer
  日本人類遺伝学会第56回大会
- Place of Presentation
  幕張
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-23701087
[Presentation] An analysis of molecular mechanisms determining oviductal epithelial cell fate decision2009
- Author(s)
  岡田淳雅, 梅津知宏, 友岡康弘
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-19570062
[Presentation] マウス胎仔卵管由来株細胞を用いた繊毛形成もモデルの確立2008
- Author(s)
  山野内裕美, 梅津知宏, 友岡康弘
- Organizer
  日本動物学会第79大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19570062
[Presentation] Identification of a novel stromal diffusible factor determining epithelial cell fate decision2008
- Author(s)
  梅津知宏, 山野内裕美, 金田浩平, 辻本高弘, 友岡康弘
- Organizer
  第41大会日本発生生物学会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-19570062
[Presentation] 膣上皮における多層化メカニズムの解析2008
- Author(s)
  浅田太一, 梅津知宏, 大瀬賢介, 村上康文, 友岡康弘
- Organizer
  日本動物学会第79大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19570062
[Presentation] 卵管上皮の運命決定メカニズムの解析2008
- Author(s)
  梅津知宏, 金田浩平, 辻本高弘, 友岡康弘
- Organizer
  日本動物学会第79大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19570062
[Presentation] マウス卵管上皮の運命決定に関与する間質由来因子の同定2007
- Author(s)
  梅津知宏
- Organizer
  日本動物学会
- Place of Presentation
  弘前
- Data Source
  KAKENHI-PROJECT-19570062
[Presentation] 胎仔マウス卵管上皮由来株細胞を用いた繊毛形成モデルの確立2007
- Author(s)
  山野内裕美, 梅津知宏, 友岡康弘
- Organizer
  日本動物学会第78大会
- Place of Presentation
  弘前
- Data Source
  KAKENHI-PROJECT-19570062
[Presentation] マウス卵管上皮細胞種の決定メカニズムの解析2007
- Author(s)
  梅津知宏
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19570062
[Presentation] マウス卵管上皮の運命決定を担う間質由来因子の同定2007
- Author(s)
  梅津知宏, 浅沼帆高, 河西優美, 友岡康弘
- Organizer
  日本動物学会第78大会
- Place of Presentation
  弘前
- Data Source
  KAKENHI-PROJECT-19570062
[Presentation] マウス卵管上皮種の決定メカニズムの解析2007
- Author(s)
  梅津知宏, 浅沼帆高, 河西優美, 友岡康弘
- Organizer
  BMB2007(第30回日本分子生物学会年会・第80回日本生化学会大会合同大会)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19570062
[Presentation] がん微小環境を制御するエクソソーム含有miRNA：長期低酸素曝露した骨髄腫細胞由来exosomal miR-135bの機能解析.
- Author(s)
  Umezu T
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25830089
[Presentation] Hypoxia enhances angiogenesis via exosomal miR-135b derived from multiple myeloma cells.
- Author(s)
  Umezu T
- Organizer
  International Society for Extracellular vesicles 2014
- Place of Presentation
  Rotterdam, Netherland
- Year and Date
  2014-04-11 – 2014-04-13
- Data Source
  KAKENHI-PROJECT-25830089
[Presentation] がん微小環境ネットワークにおけるエクソソーム含有miRNAの機能解析
- Author(s)
  梅津知宏
- Organizer
  第8回エピジェネティクス研究会
- Place of Presentation
  東京
- Year and Date
  2014-05-25 – 2014-05-27
- Data Source
  KAKENHI-PROJECT-25830089
[Presentation] テロメアRNA (TelRNA)を指標とした５―アザシチジン有効性の予測
- Author(s)
  大屋敷純子、梅津知宏、今西　哲、東　剣虹、小林千晶、大屋敷一馬
- Organizer
  第59回日本人類遺伝学会・第21回日本遺伝子診療学会合同大会
- Place of Presentation
  タワーホール船堀、船堀、東京
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-24501344

1. OHYASHIKI Junko (20191950)

# of Collaborated Projects: 3 results

# of Collaborated Products: 59 results
2. TOMOOKA Yasuhiro (10197949)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
3. SAKAKURA Teruyo (80073120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. OKADA Atsumasa (00535809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. Ohyashiki Kazuma (20201387)

# of Collaborated Projects: 1 results

# of Collaborated Products: 26 results
6. Yoshizawa Seiichiro (70421063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
7. Kuroda Masahiko (80251304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
8. 須藤カツ子 (50126091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 大野慎一郎 (90513680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. USUI Yoshihiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. OSHIMA Masanobu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. MURAKAMI Yoshiki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 宮川聡美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 善本隆之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. 田口善弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. 高梨正勝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Umedu Tomohiro 梅津 知宏

UMEZU Tomohiro 梅津 知宏

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老化ステータス異常がCAFの多様性に与える影響とその役割の解明Principal Investigator

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Analysis of the mechanism of ncRNA-mediated carcinogenesis using the DICER1 syndrome model

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Analysis of age-related genetic changes in non-tumour tissues - Investigating links to mechanisms of cancer-associated fibroblast developmentPrincipal Investigator

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Secretome analysis of tumor stroma involved in the process of cancer progressionPrincipal Investigator

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Novel therapies development of multiple myeloma using engineering exosomes derived from bone marrow stromal cells

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Analysis of novel pathogenesis of cancer-associated fibroblast involved in age-related stromal exosome changesPrincipal Investigator

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Development of novel diagnostics for hematological malignancy on basis of the exosome analysis

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Altered Exosomal miRNA expression of late onset acute graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.

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Cell-to-cell communication between tumor cell and their microenvironment via exosomesPrincipal Investigator

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Telomere repeat-containing RNA (TERRA), a possible molecular marker of leukemia

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Detection method for quantifying global DNA methylation byfluorescence correlation spectroscopyPrincipal Investigator

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Mechanisms determining epithelial cell fate decisions by mesenchyme

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[Journal Article] Plasma extracellular vesicle microRNAs reflecting the therapeutic effect of the CBP/β-catenin inhibitor PRI-724 in patients with liver cirrhosis.2024

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Umedu Tomohiro 梅津知宏

UMEZU Tomohiro 梅津知宏