Tomiyama Arata 富山新太

… Alternative Names

TOMIYAMA Arata 富山新太

Less

Researcher Number	40385810
Other IDs
Affiliation (Current)	2025: 順天堂大学, 医学部, 非常勤講師 2025: 東邦大学, 医学部, 研究員 2025: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 病院脳神経外科, 講師
Affiliation (based on the past Project Information) *help	2025: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 病院脳神経外科, 講師 2017 – 2023: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 病院脳神経外科, 講師 2016: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 病院脳神経外科, 講師 2008 – 2011: Yamagata University, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Cerebral neurosurgery / Neurosurgery Except Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery / Clinical oncology / Cerebral neurosurgery
Keywords	Principal Investigator 非ジャーミノーマ性胚細胞腫瘍 / 頭蓋内胚細胞腫瘍 / エネルギー代謝 / グリオーマ / 非ジャーミノーマ胚細胞腫 / 新規分子治療標的開発 / マイクロRNA / 中枢神経系胚細胞腫瘍 / トランスレーショナルリサーチ / シグナル伝達 … More / 基礎腫瘍学 / 胚細胞腫 / 動物モデル / 分子シグナル / NGGCT / ジャーミノーマ / c-KIT変異 / 中枢性胚細胞腫 / 脱ユビキチン化酵素 / ドライバー変異 / MEK1/2 / ユビキチン化 / USP28 / 非ジャーミノーマ胚細胞腫瘍 / Warburg effect / テモゾロミド … More Except Principal Investigator 中枢神経系悪性リンパ腫 / 治療耐性 / 予後因子 / 予測因子 / 標準治療 / びまん性大細胞型B細胞リンパ腫 / 微小環境解析 / 腫瘍内多様性 / シングルセル解析 / 分子標的知慮 / シグナル伝達 / 転移機序 / 遺伝子解析 / 脳腫瘍 / 部位特異的変異導入法 / 分子標的治療 / 遺伝子変異解析 / 二次性中枢神経系悪性リンパ腫 / NF-kB / BAD / PIM1 / 化学療法 / がん / ケミカルバイオロジー / 抗がん物質探索 / mTOR / PI3K / 造腫瘍能 / 悪性脳腫瘍 / 幹細胞 / グリオーマ / 脳腫瘍学 Less

Epigenetic reader domain制御異常による小児脳腫瘍の新たな発がんメカニズムの探索Principal Investigator
- Principal Investigator
  
  富山新太
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  National Defense Medical College
Functional analysis of oncogenic microRNAs identified by comprehensive methylation analysis in the regulation of oncogenic roles of central nervous system germ cell tumorsPrincipal Investigator
- Principal Investigator
  
  Tomiyama Arata
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  National Defense Medical College
Investigation of tumor heterogeneity and microenvironment of primary central nervous system lymphoma and development of novel therapeutic strategies
- Principal Investigator
  
  Nagane Motoo
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyorin University
Identification of novel oncogenic mutations of a molecule which are specifically occurred in and regulate oncogenicity of intracranial non-germinomatous germ cell tumorsPrincipal Investigator
- Principal Investigator
  
  Tomiyama Arata
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  National Defense Medical College
Functional analysis of specific genetic alterations in primary central nervous system lymphomas and development of novel molecular targeted therapies
- Principal Investigator
  
  Nagane Motoo
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Kyorin University
Overcomingtherapy resistanceofintractable cancersviamodulation of mitochondrial energy metabolism
- Principal Investigator
  
  SEINO Shizuka
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Clinical oncology
- Research Institution
  Yamagata University
Overcoming therapy resistance of glioma cells via modulation of mitochondrial energy metabolismPrincipal Investigator
- Principal Investigator
  
  TOMIYAMA Arata
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Yamagata University
Overcoming therapy resistance of glioma via elucidation of the mechanisms underlying glioma stem cell maintenance
- Principal Investigator
  
  KITANAKA Chifumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Yamagata University
Overcoming therapy resistance of glioma cells via modulation of mitochondrial energy metabolismPrincipal Investigator
- Principal Investigator
  
  TOMIYAMA Arata
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Yamagata University

All 2023 2022 2020 2019 2018 2011 2010 2009 2008

All Journal Article Presentation

[Journal Article] A common deletion at BAK1 reduces enhancer activity and confers risk of intracranial germ cell tumors2022
- Author(s)
  Sonehara K、Kimura Y、Nakano Y、Ozawa T、Takahashi M、Suzuki K、Fujii T、Matsushita Y、Tomiyama A、Kishikawa T、Yamamoto K、Naito T、Suzuki T、Yamaguchi S、Miwa T、Sasaki H、Kitagawa M、Ohe N、Fukai J、Ogiwara H、Kawamura A、Miyawaki S、Matsuda F、Kiyokawa N、Ichimura K、Nishikawa R、Okada Y、Terashima K
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 4478-4478
- DOI
  10.1038/s41467-022-32005-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09380, KAKENHI-PROJECT-21K09161, KAKENHI-PROJECT-22H00476
[Journal Article] GCT-22. PROTEIN DEUBIQUITINATION PATHWAY IS A NOVEL THERAPEUTIC TARGET AGAINST MALIGNANT NON-GERMINOMATOUS CNS GERM CELL TUMORS2020
- Author(s)
  Arata Tomiyama, Eita Uchida, Kojiro Wada, Koichi Ichimura
- Journal Title
  
  Neuro-Oncology
  
  Volume: Volume 22, Issue Supplement_3 Issue: Supplement_3 Pages: iii332-iii332
- DOI
  10.1093/neuonc/noaa222.242
- Data Source
  KAKENHI-PROJECT-17K10882
[Journal Article] CBMS-11 PROTEIN DEUBIQUITINATION PATHWAY IS A NOVEL THERAPEUTIC TARGET AGAINST MALIGNANT CNS NON-GERMINOMATOUS GERM CELL TUMORS2020
- Author(s)
  Arata Tomiyama, Eita Uchida, Daisuke Kawauchi, Kojiro Wada, Kouchi Ichimura
- Journal Title
  
  Neuro-Oncology Advances
  
  Volume: Volume 2, Issue Supplement_3 Issue: Supplement_3 Pages: ii4-ii5
- DOI
  10.1093/noajnl/vdaa143.018
- Data Source
  KAKENHI-PROJECT-17K10882
[Journal Article] ＜こっそり入門脳神経外科医のための分子生物学＞ ◆今さら聞けない臨床に必要な遺伝子診断・今さらですが…… 小児脳腫瘍に特徴的な遺伝子異常，特に今回はグリオーマ以外の話も交えて2019
- Author(s)
  富山新太、市村幸一、森健太郎
- Journal Title
  
  脳神経外科速報
  
  Volume: vol.29 no.3 Pages: 284-292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10882
[Journal Article] SPDR-06 PROTEIN DEUBIQUITINATION PATHWAY IS A NOVEL THERAPEUTIC TARGET AGAINST MALIGNANT CNS NON-GERMINOMATOUSPDR-06 PROTEIN DEUBIQUITINATION PATHWAY IS A NOVEL THERAPEUTIC TARGET AGAINST MALIGNANT CNS NON-GERMINOMATOUS GERM CELL TUMORSS GERM CELL TUMORS2019
- Author(s)
  Arata Tomiyama, Eita Uchida,Arata Tomiyama, Eita Uchida, Tatsuya Kobayashi, Kojiro Wada, Kouichi Ichimura Tatsuya Kobayashi, Kojiro Wada, Kouichi Ichimura
- Journal Title
  
  Neuro-Oncology Advances
  
  Volume: Vol 1, Supplement_2 Issue: Supplement_2 Pages: ii47-ii53
- DOI
  10.1093/noajnl/vdz039
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10882
[Journal Article] ＜こっそり入門脳神経外科医のための分子生物学＞ ◆今さら聞けない臨床に必要な遺伝子診断・今さらですが…… 小児脳腫瘍に特徴的な遺伝子異常，特に今回はグリオーマ以外の話も交えて2019
- Author(s)
  富山　新太、市村　幸一、森　健太郎
- Journal Title
  
  脳神経外科速報
  
  Volume: vol.29 no.3 Pages: 284-292
- Data Source
  KAKENHI-PROJECT-17K10882
[Journal Article] Mechanisms of cell death inhibition through change in subcellular localization of Pim-1 by PIM1 gene mutation recurrently found in primary central nervous system lymphoma2019
- Author(s)
  Sasaki N, Ichimura K, Nagane M, Tomiyama A
- Journal Title
  
  Neuro-Oncology Advances
  
  Volume: 1 Issue: Supplement_2 Pages: ii34-ii34
- DOI
  10.1093/noajnl/vdz039.154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05442
[Journal Article] FoxO3a functions as a key integrator of cellular signals that control glioblastoma stem-like cell differentiation and tumorigenicity2011
- Author(s)
  Sunayama J, Sato A, Matsuda KI, Tachibana K, Watanabe E, Seino S, Suzuki K, Narita Y, Shibui S, Sakurada K, Kayama T, Tomiyama A, Kitanaka C
- Journal Title
  
  Stem Cells
  
  Volume: 29 Pages: 1327-1337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390402
[Journal Article] FoxO 3a functions as a key integrator of cellular signals that control glioblastoma stem-like cell differentiation and tumorigenicity2011
- Author(s)
  Sunayama J, Sato A, Matsuda KI, Tachibana K, Watanabe E, Seino S, Suzuki K, Narita Y, Shibui S, Sakurada K, Kayama T, Tomiyama A, Kitanaka C
- Journal Title
  
  Stem Cells
  
  Volume: 29 Pages: 1327-1337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791331
[Journal Article] MEK-ERK signaling dictates DNA-repair gene MGMT expression and temozolomide resistance of stem-like glioblastoma cells via the MDM2-p53 axis2011
- Author(s)
  Sato A, Sunayama J, Matsuda K, Seino S, Suzuki K, Watanabe E, Tachibana K, Tomiyama A, Kayama T, Kitanaka C
- Journal Title
  
  Stem Cells
  
  Volume: 29 Pages: 1942-1951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791331
[Journal Article] MEK-ERK signaling dictates DNA-repair gene MGMT expression and temozolomide resistance of stem-like glioblastoma cells via the MDM2-p53 axis2011
- Author(s)
  Sato A, Sunayama J, Matsuda K, Seino S, Suzuki K, Watanabe E, Tachibana K, Tomiyama A, Kayama T, Kitanaka C
- Journal Title
  
  StemCells
  
  Volume: 29 Pages: 1942-1951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390402
[Journal Article] FoxO3a functions as a key integrator of cellular signals that control glioblastoma stem-like cell differentiation and tumorigenicity2011
- Author(s)
  Sunayama J, Sato A, Matsuda KI, Tachibana K, Watanabe E, Seino S, Suzuki K, Narita Y, Shibui S, Sakurada K, Kayama T, Tomiyama A, Kitanaka C
- Journal Title
  
  Stem Cells
  
  Volume: 29 Pages: 1327-1337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650235
[Journal Article] MEK-ERK signaling dictates DNA-repair gene MGMT expression and temozolomide resistance of stem-like glioblastoma cells via the MDM2-p53 axis2011
- Author(s)
  Sato A, Sunayama J, Matsuda K, Seino S, Suzuki K, Watanabe E, Tachibana K, Tomiyama A, Kayama T, Kitanaka C
- Journal Title
  
  StemCells
  
  Volume: 29 Pages: 1942-1951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650235
[Journal Article] Dual blocking of mTor and PI3K elicits a pro-differentiation effect on glioblastoma stem like-cells2010
- Author(s)
  Sunayama J, Sato A, Matsuda KI, Tachibana K, Suzuki K, Narita Y, Shibui S, Sakurada K, Kayama T, Tomiyama A, Kitanaka C
- Journal Title
  
  Neuro-Oncol
  
  Volume: 12 Pages: 1205-1219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390402
[Journal Article] Regulation of neural stem/progenitor cell maintenance by PI3K and mTOR.2010
- Author(s)
  Sato A, Sunayama J, Matsuda K, Tachibana K, Sakurada K, Tomiyama A, Kayama T, Kitanaka C.
- Journal Title
  
  Neurosci Lett 470
  
  Pages: 115-120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791002
[Journal Article] Dual blocking of mTor and PI3K elicits a pro-differentiation effect on glioblastoma stem like-cells2010
- Author(s)
  Sunayama J, Sato A, Matsuda KI, Tachibana K, Suzuki K, Narita Y, Shibui S, Sakurada K, Kayama T, Tomiyama A, Kitanaka C
- Journal Title
  
  Neuro-Oncol
  
  Volume: 12 Pages: 1205-1219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791331
[Journal Article] MEK-ERK-dependent multiple caspase activation via mitochondrial proapoptotic Bcl-2 family proteins is essential for heavy ion irradiation-induced glioma celldeath2010
- Author(s)
  Tomiyama A, Tachibana K, Suzuki K, Seino S, Sunayama J, Matsuda KI, Sato A, Matsumoto Y, Nomiya T, Nemoto K, Yamashita H, Kayama T, Ando K, Kitanaka C
- Journal Title
  
  Cell Death Dis
  
  Volume: 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390402
[Journal Article] Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells2010
- Author(s)
  Sunayama J, Matsuda KI, Sato A, Tachibana K, Suzuki K, Narita Y, Shibui S, Sakurada K, Kayama T, Tomiyama A, Kitanaka C
- Journal Title
  
  Stem Cells
  
  Volume: 28 Pages: 1930-1939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791331
[Journal Article] Regulation of neural stem/progenitor cell maintenance by PI3K and mTOR2010
- Author(s)
  Sato A, Sunayama J, Matsuda KI, Tachibana K, Sakurada K, Tomiyama A, Kayama T, Kitanaka C
- Journal Title
  
  Neurosci Lett
  
  Volume: 410 Pages: 115-120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390402
[Journal Article] MEK-ERK-dependent multiple caspase activation via mitochondrial proapoptotic Bcl-2 family proteins is essential for heavy ion irradiation-induced glioma cell death2010
- Author(s)
  Tomiyama A, Tachibana K, Suzuki K, Seino S, Sunayama J, Matsuda KI, Sato A, Matsumoto Y, Nomiya T, Nemoto K, Yamashita H, Kayama T, Ando K, Kitanaka C
- Journal Title
  
  Cell Death Dis
  
  Volume: 1 Issue: 7 Pages: e60-e60
- DOI
  10.1038/cddis.2010.37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650235
[Journal Article] MEK-ERK-dependent multiple caspase activation via mitochondrial proapoptotic Bcl-2 family proteins is essential for heavy ion irradiation-induced glioma cell death2010
- Author(s)
  Tomiyama A, et al.
- Journal Title
  
  Cell Death Dis
  
  Volume: 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650235
[Journal Article] Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells2010
- Author(s)
  Sunayama J, Matsuda KI, Sato A, Tachibana K, Suzuki K, Narita Y, Shibui S, Sakurada K, Kayama T, Tomiyama A, Kitanaka C
- Journal Title
  
  StemCells
  
  Volume: 28 Pages: 1930-1939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390402
[Journal Article] Downregulation of Ras C-terminal processing by JNK inhibition.2008
- Author(s)
  Mouri W, Tachibana K, Tomiyama A, Sunayama J, Sato A, Sakurada K, Kayama T, Kitanaka C.
- Journal Title
  
  Biochem Biophys Res Commun 371
  
  Pages: 273-277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791002
[Presentation] GENOME-WIDE ASSOCIATION STUDY OF INTRACRANIAL GERM CELL TUMORS: A COMMON DELETION AT BAK1 ATTENUATES THE ENHANCER ACTIVITY AND CONFERS RISK FOR THE BRAIN TUMORS IN CHILDREN ADOLESCENTS AND YOUNG ADULTS2023
- Author(s)
  Keita Terashima, Kyuto Sonehara, Yui Kimura, Yoshiko Nakano, Tatsuya Ozawa, Meiko Takahashi, Kenji Suzuki, Takashi Fujii, Yuko Matshita, Arata Tomiyama, et. al.
- Organizer
  Pediatric Neuro-Oncology Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09380
[Presentation] Keynote Lecture　<Research＞　超・研究入門　脳腫瘍研究.2022
- Author(s)
  富山新太
- Organizer
  第149回　一般社団法人日本脳神経外科学会関東支部学術集会.
- Invited
- Data Source
  KAKENHI-PROJECT-20K09380
[Presentation] BCL2 Dependent Pathway may be Novel Treatment Target for CNS Non-Germinomatous Germ Cell Tumors2022
- Author(s)
  Takashi FUJII、Yoshitaka NARITA、Yoshinao ODA, Akihide KONDO、Kojiro WADA、Koichi ICHIMURA、Arata TOMIYAMA
- Organizer
  第40回　日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-20K09380
[Presentation] Protein deubiquitination pathway is a novel therapeutic target against malignant non-germinomatous CNS germ cell tumors2020
- Author(s)
  Arata Tomiyama, Eita Uchida, Daisuke Kawauchi1, Kojiro Wada, Koichi Ichimura
- Organizer
  第38回日本脳腫瘍学会学術集会（国際学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10882
[Presentation] Protein deubiquitination pathway is a novel therapeutic target against malignant non-germinomatous CNS germ cell tumors2020
- Author(s)
  Arata Tomiyama, Eita Uchida, Daisuke Kawauchi1, Kojiro Wada, Koichi Ichimura
- Organizer
  ISPNO2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10882
[Presentation] Protein deubiquitination pathway is a novel therapeutic target against malignant non-germinomatous CNS germ cell tumors2020
- Author(s)
  Arata Tomiyama, Eita Uchida, Daisuke Kawauchi1, Kojiro Wada, Koichi Ichimura
- Organizer
  日本脳神経外科学会第79回学術総会（国際学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10882
[Presentation] 脱ユビキチン化反応関連分子ならびにMAPK経路は　高悪性度中枢性胚細胞腫の治療標的となり得る。2019
- Author(s)
  富山　新太、内田　栄太、小林　達弥、和田　孝次朗、市村　幸一
- Organizer
  日本脳神経外科学会第78回学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10882
[Presentation] PROTEIN DEUBIQUITINATION PATHWAY IS A NOVEL THERAPEUTIC TARGET AGAINST MALIGNANT CNS NON-GERMINOMATOUS GERM CELL TUMORS2019
- Author(s)
  Arata Tomiyama, Eita Uchida, Tatsuya Kobayashi, Kojiro Wada, Kouichi Ichimura
- Organizer
  第37回日本脳腫瘍学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10882
[Presentation] 中枢性胚細胞腫の新規治療標的の探索・・・抗てんかん薬の役割も考慮して2019
- Author(s)
  富山　新太、内田　栄太、市村　幸一
- Organizer
  脳腫瘍治療k懇話会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10882
[Presentation] 中枢性胚細胞腫の新規治療標的の探索・・・抗てんかん薬の役割も考慮して2019
- Author(s)
  富山新太、内田栄太、市村幸一
- Organizer
  東京脳腫瘍治療懇話会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10882
[Presentation] 中枢神経系悪性リンパ腫におけるPIM1遺伝子変異はPim-1細胞内局在の変化およびBADリン酸化の亢進を介して細胞死を抑制する2018
- Author(s)
  佐々木重嘉、市村幸一、永根基雄、富山新太
- Organizer
  第36回日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05442
[Presentation] Mutation of PIM1 gene in Primary Central Nervous System Lymphoma inhibits cell death through change in subcellular localization of Pim-1 and increase of BAD phosphorylation2018
- Author(s)
  佐々木重嘉、市村幸一、永根基雄、富山新太
- Organizer
  The 23rd Annual Scientific Meeting of the Society of Neuro-Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05442
[Presentation] グリオーマ幹細胞におけるFoxO3aを介した分化と造腫瘍能の制御2011
- Author(s)
  佐藤篤, 砂山潤, 松田憲一朗, 立花研, 渡部江梨子, 清野静香, 鈴木香, 成田善孝, 渋井壮一郎, 富山新太, 北中千史, 嘉山孝正
- Organizer
  第29回日本脳腫瘍学会学術総会
- Place of Presentation
  下呂(水明館)
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22791331
[Presentation] グリオーマ幹細胞における FoxO3aを介した分化と造腫瘍能の制御2011
- Author(s)
  佐藤篤,砂山潤,松田憲一朗,立花研,渡部江梨子,清野静香,鈴木香,成田善孝,渋井壮一郎,富山新太,北中千史,嘉山孝正
- Organizer
  第29回日本脳腫瘍学会学術総会
- Place of Presentation
  下呂(水明館)
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22650235
[Presentation] グリオーマ幹細胞におけるMGMT発現制御の分子機構に関する検討2011
- Author(s)
  佐藤篤,松田憲一朗,砂山潤,清野静香,鈴木香,渡部江梨子,立花研,富山新太,北中千史,嘉山孝正
- Organizer
  第12回日本分子脳神経外科学会
- Place of Presentation
  横浜(パシフィコ横浜)
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-22650235
[Presentation] グリオーマ幹細胞における FoxO3aを介した分化と造腫瘍能の制御2011
- Author(s)
  佐藤篤,砂山潤,松田憲一朗,立花研,渡部江梨子,清野静香,鈴木香,成田善孝,渋井壮一郎,富山新太,北中千史,嘉山孝正
- Organizer
  第29回日本脳腫瘍学会学術総会
- Place of Presentation
  下呂(水明館)
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-21390402
[Presentation] MEK経路阻害によるMGMT発現およびテモゾロミド感受性に関する検討2011
- Author(s)
  佐藤篤,松田憲一朗,砂山潤,清野静香,鈴木香,櫻田香,立花研,富山新太,北中千史,嘉山孝正
- Organizer
  第70回日本脳神経外科学会総会
- Place of Presentation
  横浜(パシフィコ横浜)
- Year and Date
  2011-10-12
- Data Source
  KAKENHI-PROJECT-21390402
[Presentation] MEK inhibition enhances temozolomide sensitivity of glioma stem-like cells via MGMTdown-regulation2011
- Author(s)
  Sato A, Matsuda KI, Sunayama J, Sakurada K, Tachibana K, Tomiyama A, Kitanaka C, Kayama T
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋(名古屋国際会議場)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21390402
[Presentation] MEK inhibition enhances temozolomide sensitivity of glioma stem-like cells via MGMT down-regulation2011
- Author(s)
  Sato A, Matsuda KI, Sunayama J, Sakurada K, Tachibana K, Tomiyama A, Kitanaka C, Kayama T
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋(古屋国際会議場)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22791331
[Presentation] MEK経路阻害によるMGMT発現およびテモゾロミド感受性に関する検討2011
- Author(s)
  佐藤篤,松田憲一朗,砂山潤,清野静香,鈴木香,櫻田香,立花研,富山新太,北中千史,嘉山孝正
- Organizer
  第70回日本脳神経外科学会総会
- Place of Presentation
  横浜(パシフィコ横浜)
- Year and Date
  2011-10-12
- Data Source
  KAKENHI-PROJECT-22650235
[Presentation] グリオーマ幹細胞におけるMGMT発現制御の分子機構に関する検討2011
- Author(s)
  佐藤篤,松田憲一朗,砂山潤,清野静香,鈴木香,渡部江梨子,立花研,富山新太,北中千史,嘉山孝正
- Organizer
  第12回日本分子脳神経外科学会
- Place of Presentation
  横浜(パシフィコ横浜)
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-21390402
[Presentation] グリオーマ幹細胞におけるMGMT発現とテモゾロミド感受性に関する検討2010
- Author(s)
  佐藤篤,松田憲一朗,砂山潤,清野静香,鈴木香,櫻田香,立花研,富山新太,北中千史,嘉山孝正
- Organizer
  第28回日本脳腫瘍学会
- Place of Presentation
  軽井沢(軽井沢プリンスホテル)
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-22650235
[Presentation] グリオーマ幹細胞におけるMGMT発現とテモゾロミド感受性に関する検討2010
- Author(s)
  佐藤篤, 松田憲一朗, 砂山潤, 清野静香, 鈴木香, 櫻田香, 立花研, 富山新太, 北中千史, 嘉山孝正
- Organizer
  第28回日本脳腫瘍学会
- Place of Presentation
  軽井沢(軽井沢プリンスホテル)
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-22791331
[Presentation] グリオーマ幹細胞における MGMT発現とテモゾロミド感受性に関する検討2010
- Author(s)
  佐藤篤 ,松田憲一朗 ,砂山潤 ,清野静香 ,鈴木香 ,櫻田香 ,立花研 ,富山新太 ,北中千史 ,嘉山孝正
- Organizer
  第28回日本脳腫瘍学会
- Place of Presentation
  軽井沢(軽井沢プリンスホテル)
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-21390402
[Presentation] Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the regulation of stemness of glioblastoma stem cells2010
- Author(s)
  Sunayama J, Matsuda KI, Sato A, Tachibana K, Narita Y, Shibui S, Sakurada K, Kayama T, Tomiyama A, Kitanaka C
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪(大阪国際会議場)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22791331
[Presentation] Regulation of neural stem/progenitor cell maintenance by PI3K and mTOR2010
- Author(s)
  Sato A, Sunayama J, Matsuda KI, Tachibana K, Sakurada K, Tomiyama A, Kayama T, Kitanaka C
- Organizer
  The 18^<th> International Conference on Brain Tumor Research and Therapy
- Place of Presentation
  Travemuende (Gran Spa Resort Arosa Travemuende)
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21390402
[Presentation] Mechanism of heavy ion radiation-induced glioma cell death2010
- Author(s)
  Tomiyama A, et al.
- Organizer
  日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22791331
[Presentation] Mechanism of heavy ion radiation-induced glioma cell death.2009
- Author(s)
  Tomiyama A, Sunayama J, Tachibana K, Matsuda K, Ando K, Kayama T, Kitanaka C
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20791002
[Presentation] Effect of rapamycin (mTOR inhibitor) and LY294002 (PI3K inhibitor) on glioblastoma stem-like cells.2009
- Author(s)
  Sunayama J, Sato A, Matsuda K, Tachibana K, Tomiyama A, Sakurada K, Kayama T, Kitanaka C
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20791002
[Presentation] Mechanism of heavy ion radiation-induced glioma cell death2009
- Author(s)
  Tomiyama A, et al.
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20791002
[Presentation] Downregulation of Ras C-terminal Processing by JNK Inhibition.2008
- Author(s)
  Mouri W, Tachibana K, Tomiyama A, Sunayama J, Sato A, Sakurada K, Kayama T, Kitanaka C
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20791002
[Presentation] Mechanism of heavy ion radiation-induced cancer cell death.2008
- Author(s)
  Tomiyama A, Nomiya T, Kitanaka C, Nemoto K, Yamashita H, Ando K, Kayama T
- Organizer
  HIMAC共同利用研究成果発表会
- Place of Presentation
  千葉
- Year and Date
  2008-04-15
- Data Source
  KAKENHI-PROJECT-20791002
[Presentation] ヒトグリオーマ細胞株A172における腫瘍幹細胞の単離・同定の試み.2008
- Author(s)
  佐藤篤, 砂山潤, 松田憲一朗, 立花研, 富山新太, 櫻田香, 北中千史, 嘉山孝正
- Organizer
  第26回日本脳腫瘍学会
- Place of Presentation
  松山
- Year and Date
  2008-11-30
- Data Source
  KAKENHI-PROJECT-20791002
[Presentation] Isolation and characterization of cancer stem-like cells from a human glioblastoma cell line A172.2008
- Author(s)
  Sato A, Sunayama J, Sakurada K, Matsuda K, Tachibana K, Tomiyama A, Kitanaka C, Kayama T
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20791002

1. 市村幸一 (40231146)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
2. KITANAKA Chifumi (70260320)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
3. Nagane Motoo (60327468)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. 立石健祐 (00512055)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NEMOTO Kenji (10208291)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. SUNAYAMA Jun (80466606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
7. TACHIBANA Ken (10400540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
8. SEINO Shizuka (80571653)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
9. 中村大志 (60771615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 大谷直樹 (20573637)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 山本祐太朗 (20785761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 森健太郎 (30200364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 里見介史 (10633977)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 片岡圭亮 (90631383)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 佐々木重嘉 (20894504)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Tomiyama Arata 富山 新太

TOMIYAMA Arata 富山 新太

Research Projects

Research Products

Co-Researchers

Epigenetic reader domain制御異常による小児脳腫瘍の新たな発がんメカニズムの探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of oncogenic microRNAs identified by comprehensive methylation analysis in the regulation of oncogenic roles of central nervous system germ cell tumorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of tumor heterogeneity and microenvironment of primary central nervous system lymphoma and development of novel therapeutic strategies

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of novel oncogenic mutations of a molecule which are specifically occurred in and regulate oncogenicity of intracranial non-germinomatous germ cell tumorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of specific genetic alterations in primary central nervous system lymphomas and development of novel molecular targeted therapies

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Overcomingtherapy resistanceofintractable cancersviamodulation of mitochondrial energy metabolism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Overcoming therapy resistance of glioma cells via modulation of mitochondrial energy metabolismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Overcoming therapy resistance of glioma via elucidation of the mechanisms underlying glioma stem cell maintenance

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Overcoming therapy resistance of glioma cells via modulation of mitochondrial energy metabolismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A common deletion at BAK1 reduces enhancer activity and confers risk of intracranial germ cell tumors2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] GCT-22. PROTEIN DEUBIQUITINATION PATHWAY IS A NOVEL THERAPEUTIC TARGET AGAINST MALIGNANT NON-GERMINOMATOUS CNS GERM CELL TUMORS2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CBMS-11 PROTEIN DEUBIQUITINATION PATHWAY IS A NOVEL THERAPEUTIC TARGET AGAINST MALIGNANT CNS NON-GERMINOMATOUS GERM CELL TUMORS2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ＜こっそり入門 脳神経外科医のための分子生物学＞ ◆今さら聞けない 臨床に必要な遺伝子診断 ・今さ らですが…… 小児脳腫瘍に特徴的な遺伝子異常，特に今回はグリオーマ以外の話も交えて2019

Author(s)

Journal Title

Data Source

[Journal Article] SPDR-06 PROTEIN DEUBIQUITINATION PATHWAY IS A NOVEL THERAPEUTIC TARGET AGAINST MALIGNANT CNS NON-GERMINOMATOUSPDR-06 PROTEIN DEUBIQUITINATION PATHWAY IS A NOVEL THERAPEUTIC TARGET AGAINST MALIGNANT CNS NON-GERMINOMATOUS GERM CELL TUMORSS GERM CELL TUMORS2019

Author(s)

Tomiyama Arata 富山新太

TOMIYAMA Arata 富山新太

[Journal Article] ＜こっそり入門脳神経外科医のための分子生物学＞ ◆今さら聞けない臨床に必要な遺伝子診断・今さらですが…… 小児脳腫瘍に特徴的な遺伝子異常，特に今回はグリオーマ以外の話も交えて2019

[Journal Article] ＜こっそり入門脳神経外科医のための分子生物学＞ ◆今さら聞けない臨床に必要な遺伝子診断・今さらですが…… 小児脳腫瘍に特徴的な遺伝子異常，特に今回はグリオーマ以外の話も交えて2019