Shimozono Satoshi 下薗哲

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SHIMOZONO Satoshi 下薗哲

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Researcher Number	40391982
Other IDs
Affiliation (Current)	2025: 帝京大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2021: 国立研究開発法人理化学研究所, 脳神経科学研究センター, 研究員 2015 – 2017: 国立研究開発法人理化学研究所, 脳科学総合研究センター, 研究員 2013 – 2014: 独立行政法人理化学研究所, 脳科学総合研究センター, 研究員 2012: 独立行政法人理化学研究所, 細胞機能探索技術開発チーム, 研究員 2009: 細胞機能探索技術開発チーム, 研究員 2007 – 2009: 独立行政法人理化学研究所, 細胞機能探索技術開発チーム, 研究員 2005 – 2006: 独立行政法人理化学研究所, 細胞機能探索技術開発チーム, 基礎科学特別研究員
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 44020:Developmental biology-related Except Principal Investigator Biological Sciences / Biological Sciences
Keywords	Principal Investigator 蛍光タンパク質 / FRET / レチノイン酸 / 拡散 / 核膜 / 蛍光共鳴エネルギー移動 / 肢芽 / 発生生物学 / 核膜の透過性 / 細胞分裂 / フォトコンバージョン … More Except Principal Investigator … More 細胞周期 / レチノイン酸 / バイオイメージング / 蛍光蛋白質 / 固体イメージング / 個体イメージング / 共鳴エネルギー移動 / 固定イメージング / 共鳴エネルギ移動 / 酸化プローブ / 細胞内結晶 / FRET / 透明化試薬 / 酸化ストレス / 蛍光たんぱく質 / イメージング / 蛍光タンパク質 / 神経前駆細胞 / 蛍光イメージング / 膜電位 / レシオイメージング Less

Visualization of retinoic acid gradients underlying the mouse limb formationPrincipal Investigator
- Principal Investigator
  
  SHIMOZONO Satoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Institute of Physical and Chemical Research
The development of fundamental bioimaging technologies for comprehensive understanding
- Principal Investigator
  
  Atsushi Miyawaki
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Institute of Physical and Chemical Research
Improvement of the genetically encoded probe for retinoic acid, GEPRA.Principal Investigator
- Principal Investigator
  
  Shimozono Satoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Institute of Physical and Chemical Research
Possible functions of the permeability barrier of the nuclear envelope.Principal Investigator
- Principal Investigator
  
  SHIMOZONO Satoshi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Institute of Physical and Chemical Research
Visualizing biological functions at many different scales
- Principal Investigator
  
  MIYAWAKI Atsushi
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Permeablity change of the nuclear envelope after mitosis.Principal Investigator
- Principal Investigator
  
  SHIMOZONO Satoshi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The Institute of Physical and Chemical Research
New approaches for imaging and controlling the molecules of life.
- Principal Investigator
  
  MIYAWAKI Atsushi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research

All 2022 2021 2019 2018 2015 2013 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

[Book] Methods Cell Biol.(Engineering FRET Constructs Using CFP and YFP., 85C)2007
- Author(s)
  Shimozono S, Miyawaki A.
- Data Source
  KAKENHI-PROJECT-17017039
[Journal Article] A highly photostable and bright green fluorescent protein2022
- Author(s)
  Hirano Masahiko、Ando Ryoko、Shimozono Satoshi、Sugiyama Mayu、Takeda Noriyo、Kurokawa Hiroshi、Deguchi Ryusaku、Endo Kazuki、Haga Kei、Takai-Todaka Reiko、Inaura Shunsuke、Matsumura Yuta、Hama Hiroshi、Okada Yasushi、Fujiwara Takahiro、Morimoto Takuya、Katayama Kazuhiko、Miyawaki Atsushi
- Journal Title
  
  Nature Biotechnology
  
  Volume: - Issue: 7 Pages: 1132-1142
- DOI
  10.1038/s41587-022-01278-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06699, KAKENHI-PROJECT-20K06736, KAKENHI-PLANNED-21H05252, KAKENHI-PROJECT-21H05041, KAKENHI-PROJECT-23K24060, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05795
[Journal Article] Single-cell bioluminescence imaging of deep tissue in freely moving animals.2018
- Author(s)
  Iwano S, Sugiyama M, Hama H, Watakabe A, Hasegawa N, Kuchimaru T, Tanaka KZ, Takahashi M, Ishida Y, Hata J, Shimozono S, Namiki K, Fukano T, Kiyama M, Okano H, Kizaka-Kondoh S, McHugh TJ, Yamamori T, Hioki H, Maki S, Miyawaki A.
- Journal Title
  
  Science
  
  Volume: 359 Issue: 6378 Pages: 935-939
- DOI
  10.1126/science.aaq1067
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07036, KAKENHI-PROJECT-17K19451, KAKENHI-PROJECT-17K13272, KAKENHI-PLANNED-15H05948, KAKENHI-PUBLICLY-16H01426, KAKENHI-PROJECT-16H04663
[Journal Article] Visualization of an endogenous retinoic acid gradient across embryonic development2013
- Author(s)
  Shimozono S. Iimura T. Kitaguchi T. Higashijima S. Miyawaki A
- Journal Title
  
  Nature
  
  Volume: 496(7445) Issue: 7445 Pages: 363-6
- DOI
  10.1038/nature12037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390417, KAKENHI-PLANNED-22113003
[Journal Article] Diffusion of large molecules into assembling nuclei revealed using an optical highlighting technique.2009
- Author(s)
  Shimozono S., Tsutsui H., Miyawaki A.
- Journal Title
  
  Biophysical Journal 97
  
  Pages: 1288-1294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790090
[Journal Article] Diffusion of large molecules into assembling nuclei revealed using an optical highlighting technique.2009
- Author(s)
  Shimozono S, Tsutsui H, Miyawaki A.
- Journal Title
  
  Biophys J. 97(5)
  
  Pages: 1288-1294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17017039
[Journal Article] Diffusion of large molecules into assembling nuclei revealed using an optical highlighting technique2009
- Author(s)
  Shimozono S, Tsutsui H, Miyawaki A
- Journal Title
  
  Biophys J. 97
  
  Pages: 288-1294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17017039
[Journal Article] Diffusion of large molecules into assembling nuclei revealed using an optical highlighting technique2009
- Author(s)
  Satoshi Shimozono
- Journal Title
  
  Biophysical Journal 97
  
  Pages: 1288-1294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790090
[Journal Article] Development of microscopic systems for high-speed dual-excitation ratiometric Ca(2+) imaging.2008
- Author(s)
  Fukano T, Shimozono S, Miyawaki A.
- Journal Title
  
  Brain Cell Biol. 36
  
  Pages: 43-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17017039
[Journal Article] Development of microscopic systems for high-speed dual-excitation ratiometric Ca(2+) imaging.2008
- Author(s)
  Fukano T, Shimozono S, Miyawaki A.
- Journal Title
  
  Brain Cell Biology 36
  
  Pages: 43-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17017039
[Journal Article] A. Engineering FRET Constructs Using CFP and YFP.2007
- Author(s)
  Shimozono S, et. al.
- Journal Title
  
  Methods Cell Biol. 85C
  
  Pages: 381-393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17017039
[Journal Article] Concatenation of Cyan and Yellow Fluorescent Proteins for Efficient Resonance Energy Transfer.2006
- Author(s)
  Shimozono S; Hosoi H; Mizuno H; Fukano T; Tahara T; Miyawaki A.
- Journal Title
  
  Biochemistry 45
  
  Pages: 6267-6271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17017039
[Journal Article] Fast dual-excitation ratiometry with light-emitting diodes and high-speed liquid crystal shutters.2005
- Author(s)
  Fukano T, Shimozono S, Miyawaki A.
- Journal Title
  
  Biochem Biophys Res Commun. 330
  
  Pages: 250-255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17017039
[Journal Article] Fast dual-excitation ratiometry with light-emitting diodes and high-speed liquid crystal shutters.2005
- Author(s)
  Fukano T, Shimozono S, Miyawaki A.
- Journal Title
  
  Biochem Biophys Res Commun. 330巻
  
  Pages: 250-255
- Data Source
  KAKENHI-PROJECT-17017039
[Presentation] 生体内レチノイン酸分布の可視化2021
- Author(s)
  下薗　哲
- Organizer
  第126回日本解剖学会、第98回日本生理学会　合同大会
- Data Source
  KAKENHI-PROJECT-19K06699
[Presentation] Visualization of retinoic acid gradients2021
- Author(s)
  下薗　哲、宮脇　敦史
- Organizer
  第126回日本解剖学会、第98回日本生理学会　合同大会
- Data Source
  KAKENHI-PROJECT-19K06699
[Presentation] Visualization of retinoic acid gradients2019
- Author(s)
  Satoshi Shimozono
- Organizer
  日本生物物理学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06699
[Presentation] RAome - omics of RA2019
- Author(s)
  Satoshi Shimozono
- Organizer
  Resonance Bio International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05948
[Presentation] Visualization of retinoic acid gradients2019
- Author(s)
  下薗哲
- Organizer
  第57回日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-15H05948
[Presentation] 生体内レチノイン酸グラディエントの定量的可視化2015
- Author(s)
  下薗　哲
- Organizer
  第347回　脂溶性ビタミン総合研究委員会
- Place of Presentation
  理化学研究所鈴木梅太郎ホール
- Year and Date
  2015-07-17
- Invited
- Data Source
  KAKENHI-PROJECT-26460089
[Presentation] Diffusion of large molecules into assembling nuclei revealed using an optical highlighting technique2009
- Author(s)
  下薗哲
- Organizer
  9^<th> NIBB-EMBL Symposium
- Place of Presentation
  愛知県岡崎市
- Year and Date
  2009-04-22
- Data Source
  KAKENHI-PROJECT-20790090
[Presentation] Diffusion of large molecules into assembling nuclei revealed using an optical highlighting technique.2009
- Author(s)
  下薗哲
- Organizer
  9th NIBB-EMBL Symposium
- Place of Presentation
  愛知県岡崎市
- Year and Date
  2009-04-22
- Data Source
  KAKENHI-PROJECT-20790090
[Presentation] 蛍光タンパク質を用いた核膜透過性の検討2009
- Author(s)
  下薗哲
- Organizer
  日本生物物理学会
- Place of Presentation
  徳島県徳島市
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-20790090
[Presentation] 蛍光タンパク質を用いた核膜透過性の検討2008
- Author(s)
  下薗哲、宮脇敦史
- Organizer
  日本生物物理学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2008-12-04
- Data Source
  KAKENHI-PROJECT-20790090
[Presentation] Visualization of an endogenous retinoic acid gradient across embryonic development
- Author(s)
  Satoshi Shimozono
- Organizer
  Rhe 37th Naito Conference
- Place of Presentation
  北海道ニセコ町
- Year and Date
  2014-07-15 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-26460089

1. MIYAWAKI Atsushi (80251445)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
2. FUKANO Takashi (80373364)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. HAMA Hiroshi (30261796)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SAKAUE Asako (90462689)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MIZUNO Hideaki (80301779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. TSUTSUI Hidekazu (30392038)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. NAGAI Takeharu (20311350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MIYAUCHI Takayuki (00392142)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SASAKI Kazuki (10415169)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NIINO Yusuke (10584584)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KAWANO Hiroyuki (10332256)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. ANDO Ryoko (10706170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 牧昌次郎 (20266349)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 小松直貴 (30737440)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. IBATA Keiji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. VETRIVEL Lakshmanan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 飯村忠浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 渡我部昭哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shimozono Satoshi 下薗 哲

SHIMOZONO Satoshi 下薗 哲

Research Projects

Research Products

Co-Researchers

Visualization of retinoic acid gradients underlying the mouse limb formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The development of fundamental bioimaging technologies for comprehensive understanding

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Improvement of the genetically encoded probe for retinoic acid, GEPRA.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Possible functions of the permeability barrier of the nuclear envelope.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Visualizing biological functions at many different scales

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Permeablity change of the nuclear envelope after mitosis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New approaches for imaging and controlling the molecules of life.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] Methods Cell Biol.(Engineering FRET Constructs Using CFP and YFP., 85C)2007

Author(s)

Data Source

[Journal Article] A highly photostable and bright green fluorescent protein2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Single-cell bioluminescence imaging of deep tissue in freely moving animals.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Visualization of an endogenous retinoic acid gradient across embryonic development2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Diffusion of large molecules into assembling nuclei revealed using an optical highlighting technique.2009

Author(s)

Journal Title

Data Source

[Journal Article] Diffusion of large molecules into assembling nuclei revealed using an optical highlighting technique.2009

Author(s)

Journal Title

Data Source

[Journal Article] Diffusion of large molecules into assembling nuclei revealed using an optical highlighting technique2009

Author(s)

Journal Title

Data Source

[Journal Article] Diffusion of large molecules into assembling nuclei revealed using an optical highlighting technique2009

Author(s)

Journal Title

Shimozono Satoshi 下薗哲

SHIMOZONO Satoshi 下薗哲