Araki Ryoko 荒木良子

… Alternative Names

ARAKI Ryoko 荒木良子

荒木良子アラキリョウコ

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Researcher Number	40392211
Other IDs	https://orcid.org/0000-0003-3972-3153
Affiliation (Current)	2025: 国立研究開発法人量子科学技術研究開発機構, 放射線医学研究所放射線規制科学研究部, 専門業務員
Affiliation (based on the past Project Information) *help	2021 – 2023: 国立研究開発法人量子科学技術研究開発機構, 量子生命科学研究所, 上席研究員 2019: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所放射線障害治療研究部, グループリーダー(定常) 2016 – 2018: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所放射線障害治療研究部, チームリーダー(定常) 2014 – 2015: 国立研究開発法人放射線医学総合研究所, 研究基盤センター, 室長 2014: 独立行政法人放射線医学総合研究所, その他部局等, 室長 … More 2012 – 2014: 独立行政法人放射線医学総合研究所, 研究基盤センター, 室長 2012: 放射線医学総合研究所, 重粒子センター, 研究員 2011: 独立行政法人放射線医学総合研究所, その他部局等, 研究員 2009: 放射線医学総合研究所, 重粒子医科学センター, チームリーダー 2007: 放射線医学総合研究所, 先端遺伝子発現研究グループ, 研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 48040:Medical biochemistry-related / Environmental analyses and evaluation and related fields / Medical genome science / Genome biology Except Principal Investigator Morphological basic dentistry / Functional basic dentistry
Keywords	Principal Investigator iPS細胞 / 変異 / 点突然変異 / ゲノム変異 / 活性酸素 / 全ゲノムシーケンシング / ゲノム初期化 / リプログラミング / 分化 / マイクロサテライト … More / 次世代シーケンシング / DNA損傷 / INDEL / SNV / 放射線 / 再生医学 / ゲノム / 酸化ストレス / ゲノムリプログラミング / ES細胞 … More Except Principal Investigator 遺伝子発現 / 転写因子 / エピジェネティクス / 細胞分化 / 遺伝子 / 分化 / 靱帯細胞 / 腱細胞 / 力学的負荷 / 転写産物 / 靱帯組織 / 腱組織 / MyoD / 転写活性 / 分化転換 / 骨格系組織 / エピジェネティック解析 / メチル化 / 間葉系細胞 / 骨格 / 軟骨細胞 / 骨格形成 / 発生 / 薬理学 Less

Reduction of genome reprogramming-associated mutationsPrincipal Investigator
- Principal Investigator
  
  Araki Ryoko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  National Institutes for Quantum Science and Technology
Reprogramming associated point mutations and ROSPrincipal Investigator
- Principal Investigator
  
  ARAKI RYOKO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical genome science
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
Development of genome-wide method for analyzing radiation effectsPrincipal Investigator
- Principal Investigator
  
  ARAKI RYOKO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Environmental analyses and evaluation and related fields
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
Search for molecular signatures that discriminate between tendon and ligament tissue
- Principal Investigator
  
  NIFUJI AKIRA
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Tsurumi University
Genome instability during genome reprogrammingPrincipal Investigator
- Principal Investigator
  
  ARAKI RYOKO
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Genome biology
- Research Institution
  National Institute of Radiological Sciences
Cellular conversion from non- skeletal to skeletal cells by using transactivation MyoD domain
- Principal Investigator
  
  NIFUJI Akira
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Tsurumi University
Epigenetic changes in cell fate decision during mesenchymal cell differentiation.
- Principal Investigator
  
  NIFUJI Akira
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Tsurumi University
Molecular approaches to identify molecules involved in the cell aggregates formation in the skeletal blastema and elucidation of their functional properties
- Principal Investigator
  
  NIFUJI Akira
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tsurumi University

[Book] 日本臨床　増刊号　再生医療「iPS化に伴う点突然変異」2015
- Author(s)
  荒木良子、杉浦真由美、笠間康次、安倍真澄
- Total Pages
  7
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-25290068
[Journal Article] Insertion/deletion and microsatellite alteration profiles in induced pluripotent stem cells2021
- Author(s)
  Kamimura Satoshi、Suga Tomo、Hoki Yuko、Sunayama Misato、Imadome Kaori、Fujita Mayumi、Nakamura Miki、Araki Ryoko、Abe Masumi
- Journal Title
  
  Stem Cell Reports
  
  Volume: 16 Issue: 10 Pages: 2503-2519
- DOI
  10.1016/j.stemcr.2021.08.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15707, KAKENHI-PROJECT-21H02689
[Journal Article] In situ delivery of iPSC-derived dendritic cells with local radiotherapy generates systemic antitumor immunity and potentiates PD-L1 blockade in preclinical poorly immunogenic tumor models2021
- Author(s)
  Oba Takaaki、Makino Kenichi、Kajihara Ryutaro、Yokoi Toshihiro、Araki Ryoko、Abe Masumi、Minderman Hans、Chang Alfred E、Odunsi Kunle、Ito Fumito
- Journal Title
  
  Journal for ImmunoTherapy of Cancer
  
  Volume: 9 Issue: 5 Pages: e002432-e002432
- DOI
  10.1136/jitc-2021-002432
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02689
[Journal Article] Genetic aberrations in iPSCs are introduced by a transient G1/S cell cycle checkpoint deficiency2020
- Author(s)
  Araki Ryoko、Hoki Yuko、Suga Tomo、Obara Chizuka、Sunayama Misato、Imadome Kaori、Fujita Mayumi、Kamimura Satoshi、Nakamura Miki、Wakayama Sayaka、Nagy Andras、Wakayama Teruhiko、Abe Masumi
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 197-197
- DOI
  10.1038/s41467-019-13830-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03615, KAKENHI-PROJECT-17K10463, KAKENHI-PROJECT-17K20053
[Journal Article] Low and High LET Ionizing Radiation-Induced Delayed Homologous Recombination Persists for Two Weeks Before Resolving.2017
- Author(s)
  C.P. Allen, H.Hirakawa, N.Izumi-Nakajima, S.Moore, J.Nie, N.Sharma, M.Sugiura, Y.Hoki, R.Araki, M.Abe, R.Okayasu, A.Fujimori and J.A.Nickoloff
- Journal Title
  
  Radiation Research
  
  Volume: 188 Issue: 1 Pages: 82-93
- DOI
  10.1667/rr14748.1
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05944, KAKENHI-PROJECT-17K20053, KAKENHI-ORGANIZER-15H05935
[Journal Article] Hotspots of De Novo Point Mutations in Induced Pluripotent Stem Cells2017
- Author(s)
  Yoshihara Masahito、Araki Ryoko、Kasama Yasuji、Sunayama Misato、Abe Masumi、Nishida Kohji、Kawaji Hideya、Hayashizaki Yoshihide、Murakawa Yasuhiro
- Journal Title
  
  Cell Reports
  
  Volume: 21 Issue: 2 Pages: 308-315
- DOI
  10.1016/j.celrep.2017.09.060
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03615, KAKENHI-PROJECT-16H06153
[Journal Article] Induced pluripotent stem cell generation-associated point mutations2015
- Author(s)
  Araki R, Sugiura M, Hoki Y, Sunayama M, Nakamura M, Kasama Y, Abe M
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 35 Pages: 226-232
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25290068
[Journal Article] Induced pluripotent stem cell generation-associated point mutations arise during the initial stages of the conversion of these cells2014
- Author(s)
  Mayumi Sugiura, Yasuji Kasama, Ryoko Araki, Yuko Hoki, Misato Sunayama, Masahiro Uda, Miki Nakamura, Shunsuke Ando and Masumi Abe
- Journal Title
  
  Stem Cell Reports
  
  Volume: 2(1) Issue: 1 Pages: 52-63
- DOI
  10.1016/j.stemcr.2013.11.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770224, KAKENHI-PROJECT-25290068
[Journal Article] Search for conditions to detect epigenetic marks and nuclear proteins in immunostaining of the testis and cartilage2014
- Author(s)
  Hisashi Ideno, Akemi Shimada, Taichi Kamiunten, Kazuhiko Imaizumi, Yoshiki Nakamura,et al
- Journal Title
  
  Journal of Histology
  
  Volume: (in press) Pages: 1-8
- DOI
  10.1155/2014/658293
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23593052, KAKENHI-PROJECT-25670784, KAKENHI-PROJECT-26462860
[Journal Article] Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells2013
- Author(s)
  Ryoko Araki
- Journal Title
  
  Nature
  
  Volume: 494 Issue: 7435 Pages: 100-104
- DOI
  10.1038/nature11807
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390344, KAKENHI-PROJECT-22592053, KAKENHI-PROJECT-23592784, KAKENHI-PROJECT-23659862, KAKENHI-PROJECT-25670784
[Journal Article] Negligible immunogenicity of terminallydifferentiated cells derived from iPSCs orESCs.2013
- Author(s)
  Araki R, Uda M, Hoki Y, Sunayama M, Nakamura M, Ando S, Sugiura M, Ideno H, Shimada A, Nifuji A, Abe M.
- Journal Title
  
  Nature 494
  
  Pages: 100-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659862
[Journal Article] Comprehensive gene expression analyses in pluripotent stem cells of a planarian, Dugesia japonica2012
- Author(s)
  Shibata, N., Hayashi, T., Fukumura, R., Fujii, J., Kudome-Takamatsu, T., Nishimura, O., Sano, S., Son, F., Suzuki, N., Araki, R., Abe, M., Agata, K.
- Journal Title
  
  International Journal of Developmental Biology
  
  Volume: 56 Issue: 1-2-3 Pages: 93-102
- DOI
  10.1387/ijdb.113434ns
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23112709, KAKENHI-PROJECT-23659862, KAKENHI-ORGANIZER-22124001
[Journal Article] A Simultaneous Space-sampling Method for DNA Fraction Collection Using a Comb Structure in Microfluidic Devices2011
- Author(s)
  Zheyu Li
- Journal Title
  
  Electrophoresis
  
  Volume: 32 Issue: 23 Pages: 3392-3398
- DOI
  10.1002/elps.201100362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23225006, KAKENHI-PROJECT-23659862, KAKENHI-PROJECT-23686026
[Journal Article] ERK signaling controls blastema cell differentiation during planarian regeneration.2011
- Author(s)
  Tasaki Junichi
- Journal Title
  
  Development
  
  Volume: 138 Issue: 12 Pages: 2417-27
- DOI
  10.1242/dev.060764
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22124001, KAKENHI-PLANNED-22124004, KAKENHI-PUBLICLY-23112709, KAKENHI-PROJECT-23659862
[Journal Article] Crucial role of c-Myc in the generation of induced pluripotent stem cells.2011
- Author(s)
  Araki R, Hoki Y, Uda M, Nakamura M, Jincho Y, Tamura C, Sunayama M, Ando S, Sugiura M, Yoshida MA, Kasama Y, Abe M
- Journal Title
  
  Stem Cells.
  
  Volume: 29(9) Issue: 9 Pages: 1362-70
- DOI
  10.1002/stem.685
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659862
[Journal Article] Nemo-like kinase (NLK) expression in osteoblastic cells and suppression of osteoblastic differentiation2010
- Author(s)
  Nifuji A, Ideno H, Ohyama Y, Takanabe R, Araki R, Abe M, Noda M, Shibuya H
- Journal Title
  
  Exp Cell Res 316(7)
  
  Pages: 1127-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390475
[Journal Article] Protein related to DAN and cerberus (PRDC) inhibits osteoblastic differentiation and its suppression promotes osteogenesis in vitro2009
- Author(s)
  Ideno H, Takanabe R, Shimada A, Imaizumi K, Araki R, Abe M, Nifuji A
- Journal Title
  
  Exp Cell Res 315(3)
  
  Pages: 474-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390475
[Patent] 誘導多能性幹細胞を製造する方法、誘導多能性幹細胞樹立過程における点変異を抑制する方法、及び誘導多能性幹細胞2019
- Inventor(s)
  荒木良子、小原千寿香、藤森ゆう子、安倍真澄
- Industrial Property Rights Holder
  量子科学技術研究開発機構
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17H03615
[Presentation] 核移植初期胚の解析によるゲノム初期化開始時の変異発生2023
- Author(s)
  上村　悟氏, 菅　智, 砂山　美里, 藤森　ゆう子, 今留　香織, 藤田　真由美, 安倍　真澄, 荒木　良子
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H02689
[Presentation] ゲノム初期化開始時の変異発生2022
- Author(s)
  上村　悟氏, 菅　智, 砂山　美里, 藤森（法喜）ゆう子, 今留　香織, 藤田　真由美, 安倍　真澄, 荒木　良子
- Organizer
  第45回日本分子生物学会年会, 日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21H02689
[Presentation] ヒトiPS細胞樹立におけるゲノム変異とその機構2021
- Author(s)
  荒木　良子, 法喜　ゆう子, 菅　智, 砂山　美里, 今留　香織, 上村　悟氏, 中村　美樹, 藤田　真由美, 安倍　真澄
- Organizer
  第48回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02689
[Presentation] iPS細胞に見られるde novo変異2021
- Author(s)
  菅　智, 法喜　ゆう子, 砂山　美里, 今留　香織, 上村　悟氏, 藤田　真由美, 中村　美樹, 荒木　良子, 安倍　真澄
- Organizer
  第44回日本分子生物学会（MBSJ）年会
- Data Source
  KAKENHI-PROJECT-21H02689
[Presentation] Microsatellite alterations in genome reprogramming2021
- Author(s)
  Kamimura Satoshi, Suga Tomo, Hoki Yuko, Sunayama Misato, Imadome Kaori, Nakamura Miki, Araki Ryoko, Fujita Mayumi, Abe Masumi
- Organizer
  第44回日本分子生物学会（MBSJ）年会
- Data Source
  KAKENHI-PROJECT-21H02689
[Presentation] Reprogrammed cellゲノムにおけるINDEL変異解析2019
- Author(s)
  上村　悟氏, 菅　智, 砂山　美里, 藤森(法喜)ゆう子, 小原　千寿香, 今留　香織, 藤田　真由美, 中村　美樹, 安倍　真澄, 荒木　良子
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03615
[Presentation] iPS細胞における点突然変異2018
- Author(s)
  荒木良子
- Organizer
  Kofu Stem Cell Conference 2018
- Data Source
  KAKENHI-PROJECT-17H03615
[Presentation] iPS細胞におけるゲノム変異 -INDEL解析-2018
- Author(s)
  菅　智, 砂山　美里, 藤森（法喜）ゆう子, 小原　千寿香, 今留　香織, 藤田　真由美, 中村　美樹, 安倍　真澄, 荒木　良子
- Organizer
  第41回日本分子生物学会年会, 日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17K20053
[Presentation] iPS細胞におけるゲノム変異 -INDEL解析-2018
- Author(s)
  菅　智, 砂山　美里, 藤森（法喜）ゆう子, 小原　千寿香, 今留　香織, 藤田　真由美, 中村　美樹, 安倍　真澄, 荒木　良子
- Organizer
  第41回日本分子生物学会年会, 日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17H03615
[Presentation] iPS細胞ゲノム内点突然変異の頻度は変えられるか？2017
- Author(s)
  藤森　ゆう子, 砂山　美里, 小原　千寿香, 今留　香織, 菅　智, 藤田　真由美, 安倍　真澄, 荒木　良子
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03615
[Presentation] ゲノム初期化多能性幹細胞コロニーに観られる点突然変異不均一性のin-depth解析2017
- Author(s)
  砂山　美里, 藤森　ゆう子, 菅　智, 小原　千寿香, 今留　香織, 荒木　良子, 安倍　真澄
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03615
[Presentation] iPS細胞ゲノム内点突然変異の頻度は変えられるか？2017
- Author(s)
  藤森　ゆう子, 砂山　美里, 小原　千寿香, 今留　香織, 菅　智, 藤田　真由美, 安倍　真澄, 荒木　良子
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K20053
[Presentation] ヒストンメチル化酵素 G9aの骨芽細胞分化における機能2016
- Author(s)
  出野尚、小松浩一郎、島田明美、新井嘉則、中島和久、荒木良子、安倍真澄、立花誠、木村宏、二藤彰
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K15679
[Presentation] ヒストンメチル化酵素G9a欠損マウスは骨形成阻害を示す2015
- Author(s)
  出野尚, 小松浩一郎, 島田明美, 上運天太一、新井嘉則、中島和久、荒木良子, 中村芳樹, 安倍真澄、立花誠、木村　宏、二藤彰
- Organizer
  第33回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-15K15679
[Presentation] Histone methyltransferase G9a is essential to progress osteoblastic differentiation in vitro, and skull bone formation in vivo2015
- Author(s)
  Ideno H, Komatsu K, Shimada A, Kamiunten T, Arai Y, Nakashima K, Araki R, Nakamura Y, Abe M, Tachibana M, Kimura H, Nifuji A.
- Organizer
  2015 ASCB Annual Meeting
- Place of Presentation
  San Diego Convention Center, San Diego, CA, USA
- Year and Date
  2015-12-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15679
[Presentation] iPS化における点突然変異生成タイミングの解析2015
- Author(s)
  砂山美里、安倍真澄、藤森（法喜）ゆう子、笠間康次、中村美樹、荒木良子
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25290068
[Presentation] A comparison of point mutations between iPS and ntES cell with whole genome sequencing2015
- Author(s)
  Yuko Fujimori-Hoki, Ryoko Araki, Misato Sunayama, Eiji Mizutani, Sayaka Wakayama, Hiroaki Nagatomo, Yasuji Kasama, Miki Nakamura, Teruhiko Wakayama, Masumi Abe
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25290068
[Presentation] Deletion of G9a, histone methyltransferase, causes impaired bone formation.2015
- Author(s)
  Ideno H, Komatsu K, Shimada A, Kamiunten T, Arai Y, Nakashima K, Araki R, Nakamura Y, Abe M, Tachibana M, Kimura H, Nifuji A
- Organizer
  ASM 2015, Joint ANZBMS, MEPSA and MBSANZ Annual Scientific Meeting
- Place of Presentation
  Hotel Grand Chancellor Hobart,Tasmania, Australia
- Year and Date
  2015-11-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15679
[Presentation] Point mutations in ES cells2013
- Author(s)
  砂山美里、杉浦真由美、法喜ゆう子、笠間康次、宇田昌広、中村美樹、安藤俊輔、荒木良子、安倍真澄
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25290068
[Presentation] iPS cells generation-associated point mutations2013
- Author(s)
  荒木良子、杉浦真由美、笠間康次、砂山美里、宇田昌広、安藤俊輔、中村美樹、法喜ゆう子、安倍真澄
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25290068
[Presentation] POINT MUTATIONS IN ES CELLS2013
- Author(s)
  Yuko Hoki, Mayumi Sugiura, Yasuji Kasama, Misato Sunayama, Masahiro Uda, Miki Nakamura, Shunsuke Ando, Ryoko Araki, Masumi Abe
- Organizer
  Society for Stem Cell Research-ISSCR 11th Annual Meeting
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-25290068
[Presentation] iPS cells generation-associated point mutations2013
- Author(s)
  Ryoko Araki, Mayumi Sugiura, Yasuji Kasama, Misato Sunayama, Masahiro Uda, Miki Nakamura, Shunsuke Ando, Yuko Hoki, Masumi Abe
- Organizer
  International Society for Stem Cell Research-ISSCR 11th Annual Meeting
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-25290068
[Presentation] MyoD mediated myogenic conversion from fibroblasts into myoblasts is blocked by cell cycle inhibition2013
- Author(s)
  Hisashi Ideno, Kazuhisa Nakashima, Yasuyuki Ohkawa, Hiroshi Kimura , Ryoko Araki , Masumi Abe , Akira Nifuji
- Organizer
  第３６回　日本分子生物学会
- Place of Presentation
  神戸国際会議場　兵庫県
- Data Source
  KAKENHI-PROJECT-25670784
[Presentation] Limited and comparable immunogenicity of terminally differentiated cells derived from both iPSCs and ESCs2012
- Author(s)
  Uda M, Araki R, Hoki Y, Sayama M, Nakamura M, Andou S, Sugiura M, IdenoH, Shimada A, Nifuji A, Abe M.
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場、福岡
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-23659862
[Presentation] MyoD-induced myogenic conversion requires cell proliferation2012
- Author(s)
  出野尚、中島和久、荒木良子、今泉和彦、二藤彰
- Organizer
  第67回日本体力医学会大会
- Place of Presentation
  長良川国際会議場岐阜
- Year and Date
  2012-09-14
- Data Source
  KAKENHI-PROJECT-23659862
[Presentation] Region-specific CpG demethylation patterns of the myogenin promoter isrequired for MyoD mediated myogenic conversion from fibroblasts into myoblasts2012
- Author(s)
  Ideno H, Nakashima K, Imaizumi K, Kasama Y, Araki R, Abe M, Nifuji A.
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場、福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-23659862
[Presentation] TSAによるmyogeninプロモーター脱メチル化制御を介した筋芽細胞への分化転換の抑制2012
- Author(s)
  出野尚、中島和久、荒木良子、今泉和彦、安倍真澄、二藤彰
- Organizer
  第30回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル、東京
- Year and Date
  2012-07-20
- Data Source
  KAKENHI-PROJECT-23659862
[Presentation] DNAメチル化阻害剤とHDAC 阻害剤による筋細胞分化制御2011
- Author(s)
  出野尚、荒木良子、今泉和彦、安倍真澄、二藤彰
- Organizer
  第66回体力医学会大会
- Place of Presentation
  下関市海峡メッセ,山口
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-23659862
[Presentation] The myogenic conversion from fibroblasts into myogenic cells is blocked by Trichostatin A through suppression of myogenin expression2011
- Author(s)
  Ideno H, Araki R,Imaizumi K, Abe M, Nifuji A.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜会議センター、神奈川
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-23659862
[Presentation] BMP antagonist PRDCの発現抑制による骨形成の促進2009
- Author(s)
  出野尚、荒木良子、今泉和彦、安倍真澄、二藤彰
- Organizer
  第64回体力医学会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-19390475
[Presentation] The BMP antagonist PRDC promotes ALP activity in the absence of BMP2009
- Author(s)
  出野尚、荒木良子、今泉和彦、安倍真澄、二藤彰
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390475
[Presentation] 骨芽細胞分化の抑制・促進双方に働くBMP antagonist PRDCの機能2009
- Author(s)
  出野尚、荒木良子、安倍真澄、二藤彰
- Organizer
  第27回骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390475
[Presentation] Masumi Abe Coordinate expression of multiple transcripts containing fragments of Line-1 retrotranposons during skeletal cell differentiation2009
- Author(s)
  Akira Nifuji, Hisashi Ideno, Ryoko Araki
- Organizer
  The 31st meeting of the American Society for Bone and Mineral Research (ASBMR)
- Place of Presentation
  Denver Co
- Data Source
  KAKENHI-PROJECT-19390475
[Presentation] 骨再生を目指したプラスミドDNAによる頭蓋骨欠損修復モデルの確立2008
- Author(s)
  荒木香映子
- Organizer
  第21回日本歯科医学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390475
[Presentation] BMP抑制分子PRDCの骨芽細胞分化における発現、制御とその機能2007
- Author(s)
  出野尚, 高鍋利依子, 荒木良子, 安倍真澄, 二藤彰
- Organizer
  第25回日本骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390475
[Presentation] Protein Related to DAN and Cerberus(PRDC)is expressed in skeletogenesis and prevents osteoblastic differentiation2007
- Author(s)
  Nifuji A, Ideno H, Takanabe R, Shimada A, Araki R, Abe M
- Organizer
  The 29th meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Honolulu
- Data Source
  KAKENHI-PROJECT-19390475
[Presentation] Protein Related to DAN and Cerberus (PRDC) is expressed in skeletogenesis and prevents osteoblastic differentiation2007
- Author(s)
  Nifuji A, Ideno H, Takanabe R, Shimada A, Araki R, Abe M
- Organizer
  The 29th meeting of the American Society for Bone and Mineral Research (ASBMR)
- Place of Presentation
  Honolulu, Hawaii
- Data Source
  KAKENHI-PROJECT-19390475
[Presentation] iPS樹立初期過程には多くのpoint mutationが生じる
- Author(s)
  藤森　ゆう子, 杉浦真由美, 笠間康次, 砂山美里, 宇田昌広, 中村美樹, 荒木良子, 安倍真澄.
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25290068
[Presentation] Lineage conversion step in iPS cell generation involves highly mutagenic process.
- Author(s)
  Ryoko Araki, Yuko Fujimori, Misato Sunayama, Yasuji Kasama, Masahiro Uda, Miki Nakamura, Masumi Abe.
- Organizer
  第12回国際幹細胞学会(ISSCR)年会
- Place of Presentation
  バンクーバー、カナダ
- Year and Date
  2014-06-18 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-25290068
[Presentation] iPS細胞クローン内細胞にみられるポイントミューテーションの不均一性
- Author(s)
  砂山　美里，荒木良子，藤森　ゆう子, 笠間康次,　宇田昌広, 中村美樹, 安倍真澄.
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25290068
[Presentation] Functions of histone methyltransferase G9a during growth and differentiation of mesenchymal cells
- Author(s)
  Ideno H1,4, Shimada A1, Kamiunten T2, Wada S2, Komatsu K1, Tachibana M3, Araki R4, Nakamura Y2, Abe M4, Nakashima K1, Nifuji A1,4
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25670784
[Presentation] The myogenic conversion from fibroblasts into myogenic cells is blocked by Trichostatin A through suppression of myogenin expression
- Author(s)
  Hisashi Ideno、Ryoko Araki、Kazuhiko Imaizumi、Masumi Abe、Akira Nifuji
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  神奈川県　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23659862
[Presentation] The functions of histone methyltransferase G9a during growth and differentiation of mesenchymal cells
- Author(s)
  出野尚1,4, 島田明美1, 上運天太一2, 和田悟史2, 小松浩一郎1, 立花誠3, 荒木良子4, 中村芳樹2, 安倍真澄4, 中島和久1,二藤彰1,4
- Organizer
  第56回歯科基礎医学会
- Place of Presentation
  福岡国際会議場（福岡県）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25670784
[Presentation] ES CELLS VS. IPS CELLS: LINEAGE CONVERSION-ASSOCIATED POINT MUTATIONS.
- Author(s)
  Yuko Fujimori, Mayumi Sugiura, Yasuji Kasama, Misato Sunayama, Masahiro Uda, Miki Nakamura, Shunsuke Ando, Ryoko Araki, Masumi Abe.
- Organizer
  第12回国際幹細胞学会(ISSCR)年会
- Place of Presentation
  バンクーバー、カナダ
- Year and Date
  2014-06-18 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-25290068
[Presentation] 間葉系細胞の増殖・分化過程におけるヒストンメチル化酵素G9aの機能
- Author(s)
  出野尚1,2, 島田明美1, 上運天太一3, 和田悟史3, 小松浩一郎1, 中島和久1, 荒木良子2, 安倍真澄2, 二藤彰1,2
- Organizer
  第32回　日本骨代謝学会
- Place of Presentation
  大阪国際会議場（大阪府）
- Year and Date
  2014-07-24 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-25670784

1. NIFUJI Akira (00240747)

# of Collaborated Projects: 4 results

# of Collaborated Products: 25 results
2. NAKASHIMA Kazuhisa (90252692)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
3. SHIBATA Tatsuya (90323708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. FUJIMORI YUKO (50415402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
5. SUNAYAMA MISATO (20625115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
6. SUGIURA MAYUMI (60397841)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
7. UDA MASAHIRO (30625893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
8. IDENO Hisashi (40435699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 江面陽一 (50333456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 島田明美 (00339813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. SHIBATA Norito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. NAKAMURA Yoshiki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 藤森亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 中島徹夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 上村悟氏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Araki Ryoko 荒木 良子

ARAKI Ryoko 荒木 良子

荒木 良子 アラキ リョウコ

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Reduction of genome reprogramming-associated mutationsPrincipal Investigator

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Reprogramming associated point mutations and ROSPrincipal Investigator

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Development of genome-wide method for analyzing radiation effectsPrincipal Investigator

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Search for molecular signatures that discriminate between tendon and ligament tissue

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Genome instability during genome reprogrammingPrincipal Investigator

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Cellular conversion from non- skeletal to skeletal cells by using transactivation MyoD domain

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Epigenetic changes in cell fate decision during mesenchymal cell differentiation.

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Molecular approaches to identify molecules involved in the cell aggregates formation in the skeletal blastema and elucidation of their functional properties

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[Book] 日本臨床 増刊号 再生医療 「iPS化に伴う点突然変異」2015

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[Journal Article] Insertion/deletion and microsatellite alteration profiles in induced pluripotent stem cells2021

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[Journal Article] In situ delivery of iPSC-derived dendritic cells with local radiotherapy generates systemic antitumor immunity and potentiates PD-L1 blockade in preclinical poorly immunogenic tumor models2021

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[Journal Article] Genetic aberrations in iPSCs are introduced by a transient G1/S cell cycle checkpoint deficiency2020

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[Journal Article] Low and High LET Ionizing Radiation-Induced Delayed Homologous Recombination Persists for Two Weeks Before Resolving.2017

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[Journal Article] Hotspots of De Novo Point Mutations in Induced Pluripotent Stem Cells2017

Araki Ryoko 荒木良子

ARAKI Ryoko 荒木良子

荒木良子アラキリョウコ

[Book] 日本臨床　増刊号　再生医療「iPS化に伴う点突然変異」2015