Araki Ryoko 荒木良子

… Alternative Names

ARAKI Ryoko 荒木良子

荒木良子アラキリョウコ

Less

Researcher Number	40392211
Other IDs	https://orcid.org/0000-0003-3972-3153
Affiliation (Current)	2025: 国立研究開発法人量子科学技術研究開発機構, 放射線医学研究所放射線規制科学研究部, シニアスタッフ 2025: 国立研究開発法人量子科学技術研究開発機構, 量子生命科学研究所, 上席研究員
Affiliation (based on the past Project Information) *help	2021 – 2023: 国立研究開発法人量子科学技術研究開発機構, 量子生命科学研究所, 上席研究員 2019: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所放射線障害治療研究部, グループリーダー(定常) 2016 – 2018: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所放射線障害治療研究部, チームリーダー(定常) 2014 – 2015: 国立研究開発法人放射線医学総合研究所, 研究基盤センター, 室長 2014: 独立行政法人放射線医学総合研究所, その他部局等, 室長 … More 2012 – 2014: 独立行政法人放射線医学総合研究所, 研究基盤センター, 室長 2012: 放射線医学総合研究所, 重粒子センター, 研究員 2011: 独立行政法人放射線医学総合研究所, その他部局等, 研究員 2009: 放射線医学総合研究所, 重粒子医科学センター, チームリーダー 2007: 放射線医学総合研究所, 先端遺伝子発現研究グループ, 研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 48040:Medical biochemistry-related / Environmental analyses and evaluation and related fields / Medical genome science / Genome biology Except Principal Investigator Morphological basic dentistry / Functional basic dentistry
Keywords	Principal Investigator iPS細胞 / 変異 / 点突然変異 / ゲノム変異 / 活性酸素 / 全ゲノムシーケンシング / ゲノム初期化 / リプログラミング / 分化 / マイクロサテライト … More / 次世代シーケンシング / DNA損傷 / INDEL / SNV / 放射線 / 再生医学 / ゲノム / 酸化ストレス / ゲノムリプログラミング / ES細胞 … More Except Principal Investigator 遺伝子発現 / 転写因子 / エピジェネティクス / 細胞分化 / 遺伝子 / 分化 / 靱帯細胞 / 腱細胞 / 力学的負荷 / 転写産物 / 靱帯組織 / 腱組織 / MyoD / 転写活性 / 分化転換 / 骨格系組織 / エピジェネティック解析 / メチル化 / 間葉系細胞 / 骨格 / 軟骨細胞 / 骨格形成 / 発生 / 薬理学 Less

Reduction of genome reprogramming-associated mutationsPrincipal Investigator
- Principal Investigator
  
  Araki Ryoko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  National Institutes for Quantum Science and Technology
Reprogramming associated point mutations and ROSPrincipal Investigator
- Principal Investigator
  
  ARAKI RYOKO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical genome science
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
Development of genome-wide method for analyzing radiation effectsPrincipal Investigator
- Principal Investigator
  
  ARAKI RYOKO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Environmental analyses and evaluation and related fields
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
Search for molecular signatures that discriminate between tendon and ligament tissue
- Principal Investigator
  
  NIFUJI AKIRA
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Tsurumi University
Genome instability during genome reprogrammingPrincipal Investigator
- Principal Investigator
  
  ARAKI RYOKO
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Genome biology
- Research Institution
  National Institute of Radiological Sciences
Cellular conversion from non- skeletal to skeletal cells by using transactivation MyoD domain
- Principal Investigator
  
  NIFUJI Akira
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Tsurumi University
Epigenetic changes in cell fate decision during mesenchymal cell differentiation.
- Principal Investigator
  
  NIFUJI Akira
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Tsurumi University
Molecular approaches to identify molecules involved in the cell aggregates formation in the skeletal blastema and elucidation of their functional properties
- Principal Investigator
  
  NIFUJI Akira
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tsurumi University

[Book] 日本臨床　増刊号　再生医療「iPS化に伴う点突然変異」2015
- Author(s)
  荒木良子、杉浦真由美、笠間康次、安倍真澄
- Total Pages
  7
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-25290068
[Journal Article] Insertion/deletion and microsatellite alteration profiles in induced pluripotent stem cells2021
- Author(s)
  Kamimura Satoshi、Suga Tomo、Hoki Yuko、Sunayama Misato、Imadome Kaori、Fujita Mayumi、Nakamura Miki、Araki Ryoko、Abe Masumi
- Journal Title
  
  Stem Cell Reports
  
  Volume: 16 Issue: 10 Pages: 2503-2519
- DOI
  10.1016/j.stemcr.2021.08.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15707, KAKENHI-PROJECT-21H02689
[Journal Article] In situ delivery of iPSC-derived dendritic cells with local radiotherapy generates systemic antitumor immunity and potentiates PD-L1 blockade in preclinical poorly immunogenic tumor models2021
- Author(s)
  Oba Takaaki、Makino Kenichi、Kajihara Ryutaro、Yokoi Toshihiro、Araki Ryoko、Abe Masumi、Minderman Hans、Chang Alfred E、Odunsi Kunle、Ito Fumito
- Journal Title
  
  Journal for ImmunoTherapy of Cancer
  
  Volume: 9 Issue: 5 Pages: e002432-e002432
- DOI
  10.1136/jitc-2021-002432
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02689
[Journal Article] Genetic aberrations in iPSCs are introduced by a transient G1/S cell cycle checkpoint deficiency2020
- Author(s)
  Araki Ryoko、Hoki Yuko、Suga Tomo、Obara Chizuka、Sunayama Misato、Imadome Kaori、Fujita Mayumi、Kamimura Satoshi、Nakamura Miki、Wakayama Sayaka、Nagy Andras、Wakayama Teruhiko、Abe Masumi
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 197-197
- DOI
  10.1038/s41467-019-13830-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03615, KAKENHI-PROJECT-17K10463, KAKENHI-PROJECT-17K20053
[Journal Article] Low and High LET Ionizing Radiation-Induced Delayed Homologous Recombination Persists for Two Weeks Before Resolving.2017
- Author(s)
  C.P. Allen, H.Hirakawa, N.Izumi-Nakajima, S.Moore, J.Nie, N.Sharma, M.Sugiura, Y.Hoki, R.Araki, M.Abe, R.Okayasu, A.Fujimori and J.A.Nickoloff
- Journal Title
  
  Radiation Research
  
  Volume: 188 Issue: 1 Pages: 82-93
- DOI
  10.1667/rr14748.1
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05944, KAKENHI-PROJECT-17K20053, KAKENHI-ORGANIZER-15H05935
[Journal Article] Hotspots of De Novo Point Mutations in Induced Pluripotent Stem Cells2017
- Author(s)
  Yoshihara Masahito、Araki Ryoko、Kasama Yasuji、Sunayama Misato、Abe Masumi、Nishida Kohji、Kawaji Hideya、Hayashizaki Yoshihide、Murakawa Yasuhiro
- Journal Title
  
  Cell Reports
  
  Volume: 21 Issue: 2 Pages: 308-315
- DOI
  10.1016/j.celrep.2017.09.060
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03615, KAKENHI-PROJECT-16H06153
[Journal Article] Induced pluripotent stem cell generation-associated point mutations2015
- Author(s)
  Araki R, Sugiura M, Hoki Y, Sunayama M, Nakamura M, Kasama Y, Abe M
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 35 Pages: 226-232
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25290068
[Journal Article] Induced pluripotent stem cell generation-associated point mutations arise during the initial stages of the conversion of these cells2014
- Author(s)
  Mayumi Sugiura, Yasuji Kasama, Ryoko Araki, Yuko Hoki, Misato Sunayama, Masahiro Uda, Miki Nakamura, Shunsuke Ando and Masumi Abe
- Journal Title
  
  Stem Cell Reports
  
  Volume: 2(1) Issue: 1 Pages: 52-63
- DOI
  10.1016/j.stemcr.2013.11.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770224, KAKENHI-PROJECT-25290068
[Journal Article] Search for conditions to detect epigenetic marks and nuclear proteins in immunostaining of the testis and cartilage2014
- Author(s)
  Hisashi Ideno, Akemi Shimada, Taichi Kamiunten, Kazuhiko Imaizumi, Yoshiki Nakamura,et al
- Journal Title
  
  Journal of Histology
  
  Volume: (in press) Pages: 1-8
- DOI
  10.1155/2014/658293
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23593052, KAKENHI-PROJECT-25670784, KAKENHI-PROJECT-26462860
[Journal Article] Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells2013
- Author(s)
  Ryoko Araki
- Journal Title
  
  Nature
  
  Volume: 494 Issue: 7435 Pages: 100-104
- DOI
  10.1038/nature11807
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390344, KAKENHI-PROJECT-22592053, KAKENHI-PROJECT-23592784, KAKENHI-PROJECT-23659862, KAKENHI-PROJECT-25670784
[Journal Article] Negligible immunogenicity of terminallydifferentiated cells derived from iPSCs orESCs.2013
- Author(s)
  Araki R, Uda M, Hoki Y, Sunayama M, Nakamura M, Ando S, Sugiura M, Ideno H, Shimada A, Nifuji A, Abe M.
- Journal Title
  
  Nature 494
  
  Pages: 100-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659862
[Journal Article] Comprehensive gene expression analyses in pluripotent stem cells of a planarian, Dugesia japonica2012
- Author(s)
  Shibata, N., Hayashi, T., Fukumura, R., Fujii, J., Kudome-Takamatsu, T., Nishimura, O., Sano, S., Son, F., Suzuki, N., Araki, R., Abe, M., Agata, K.
- Journal Title
  
  International Journal of Developmental Biology
  
  Volume: 56 Issue: 1-2-3 Pages: 93-102
- DOI
  10.1387/ijdb.113434ns
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23112709, KAKENHI-PROJECT-23659862, KAKENHI-ORGANIZER-22124001
[Journal Article] A Simultaneous Space-sampling Method for DNA Fraction Collection Using a Comb Structure in Microfluidic Devices2011
- Author(s)
  Zheyu Li
- Journal Title
  
  Electrophoresis
  
  Volume: 32 Issue: 23 Pages: 3392-3398
- DOI
  10.1002/elps.201100362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23225006, KAKENHI-PROJECT-23659862, KAKENHI-PROJECT-23686026
[Journal Article] ERK signaling controls blastema cell differentiation during planarian regeneration.2011
- Author(s)
  Tasaki Junichi
- Journal Title
  
  Development
  
  Volume: 138 Issue: 12 Pages: 2417-27
- DOI
  10.1242/dev.060764
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22124001, KAKENHI-PLANNED-22124004, KAKENHI-PUBLICLY-23112709, KAKENHI-PROJECT-23659862
[Journal Article] Crucial role of c-Myc in the generation of induced pluripotent stem cells.2011
- Author(s)
  Araki R, Hoki Y, Uda M, Nakamura M, Jincho Y, Tamura C, Sunayama M, Ando S, Sugiura M, Yoshida MA, Kasama Y, Abe M
- Journal Title
  
  Stem Cells.
  
  Volume: 29(9) Issue: 9 Pages: 1362-70
- DOI
  10.1002/stem.685
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659862
[Journal Article] Nemo-like kinase (NLK) expression in osteoblastic cells and suppression of osteoblastic differentiation2010
- Author(s)
  Nifuji A, Ideno H, Ohyama Y, Takanabe R, Araki R, Abe M, Noda M, Shibuya H
- Journal Title
  
  Exp Cell Res 316(7)
  
  Pages: 1127-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390475
[Journal Article] Protein related to DAN and cerberus (PRDC) inhibits osteoblastic differentiation and its suppression promotes osteogenesis in vitro2009
- Author(s)
  Ideno H, Takanabe R, Shimada A, Imaizumi K, Araki R, Abe M, Nifuji A
- Journal Title
  
  Exp Cell Res 315(3)
  
  Pages: 474-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390475
[Patent] 誘導多能性幹細胞を製造する方法、誘導多能性幹細胞樹立過程における点変異を抑制する方法、及び誘導多能性幹細胞2019
- Inventor(s)
  荒木良子、小原千寿香、藤森ゆう子、安倍真澄
- Industrial Property Rights Holder
  量子科学技術研究開発機構
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17H03615
[Presentation] 核移植初期胚の解析によるゲノム初期化開始時の変異発生2023
- Author(s)
  上村　悟氏, 菅　智, 砂山　美里, 藤森　ゆう子, 今留　香織, 藤田　真由美, 安倍　真澄, 荒木　良子
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H02689
[Presentation] ゲノム初期化開始時の変異発生2022
- Author(s)
  上村　悟氏, 菅　智, 砂山　美里, 藤森（法喜）ゆう子, 今留　香織, 藤田　真由美, 安倍　真澄, 荒木　良子
- Organizer
  第45回日本分子生物学会年会, 日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21H02689
[Presentation] ヒトiPS細胞樹立におけるゲノム変異とその機構2021
- Author(s)
  荒木　良子, 法喜　ゆう子, 菅　智, 砂山　美里, 今留　香織, 上村　悟氏, 中村　美樹, 藤田　真由美, 安倍　真澄
- Organizer
  第48回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02689
[Presentation] iPS細胞に見られるde novo変異2021
- Author(s)
  菅　智, 法喜　ゆう子, 砂山　美里, 今留　香織, 上村　悟氏, 藤田　真由美, 中村　美樹, 荒木　良子, 安倍　真澄
- Organizer
  第44回日本分子生物学会（MBSJ）年会
- Data Source
  KAKENHI-PROJECT-21H02689
[Presentation] Microsatellite alterations in genome reprogramming2021
- Author(s)
  Kamimura Satoshi, Suga Tomo, Hoki Yuko, Sunayama Misato, Imadome Kaori, Nakamura Miki, Araki Ryoko, Fujita Mayumi, Abe Masumi
- Organizer
  第44回日本分子生物学会（MBSJ）年会
- Data Source
  KAKENHI-PROJECT-21H02689
[Presentation] Reprogrammed cellゲノムにおけるINDEL変異解析2019
- Author(s)
  上村　悟氏, 菅　智, 砂山　美里, 藤森(法喜)ゆう子, 小原　千寿香, 今留　香織, 藤田　真由美, 中村　美樹, 安倍　真澄, 荒木　良子
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03615
[Presentation] iPS細胞における点突然変異2018
- Author(s)
  荒木良子
- Organizer
  Kofu Stem Cell Conference 2018
- Data Source
  KAKENHI-PROJECT-17H03615
[Presentation] iPS細胞におけるゲノム変異 -INDEL解析-2018
- Author(s)
  菅　智, 砂山　美里, 藤森（法喜）ゆう子, 小原　千寿香, 今留　香織, 藤田　真由美, 中村　美樹, 安倍　真澄, 荒木　良子
- Organizer
  第41回日本分子生物学会年会, 日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17K20053
[Presentation] iPS細胞におけるゲノム変異 -INDEL解析-2018
- Author(s)
  菅　智, 砂山　美里, 藤森（法喜）ゆう子, 小原　千寿香, 今留　香織, 藤田　真由美, 中村　美樹, 安倍　真澄, 荒木　良子
- Organizer
  第41回日本分子生物学会年会, 日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17H03615
[Presentation] iPS細胞ゲノム内点突然変異の頻度は変えられるか？2017
- Author(s)
  藤森　ゆう子, 砂山　美里, 小原　千寿香, 今留　香織, 菅　智, 藤田　真由美, 安倍　真澄, 荒木　良子
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03615
[Presentation] ゲノム初期化多能性幹細胞コロニーに観られる点突然変異不均一性のin-depth解析2017
- Author(s)
  砂山　美里, 藤森　ゆう子, 菅　智, 小原　千寿香, 今留　香織, 荒木　良子, 安倍　真澄
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03615
[Presentation] iPS細胞ゲノム内点突然変異の頻度は変えられるか？2017
- Author(s)
  藤森　ゆう子, 砂山　美里, 小原　千寿香, 今留　香織, 菅　智, 藤田　真由美, 安倍　真澄, 荒木　良子
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K20053
[Presentation] ヒストンメチル化酵素 G9aの骨芽細胞分化における機能2016
- Author(s)
  出野尚、小松浩一郎、島田明美、新井嘉則、中島和久、荒木良子、安倍真澄、立花誠、木村宏、二藤彰
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K15679
[Presentation] ヒストンメチル化酵素G9a欠損マウスは骨形成阻害を示す2015
- Author(s)
  出野尚, 小松浩一郎, 島田明美, 上運天太一、新井嘉則、中島和久、荒木良子, 中村芳樹, 安倍真澄、立花誠、木村　宏、二藤彰
- Organizer
  第33回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-15K15679
[Presentation] Histone methyltransferase G9a is essential to progress osteoblastic differentiation in vitro, and skull bone formation in vivo2015
- Author(s)
  Ideno H, Komatsu K, Shimada A, Kamiunten T, Arai Y, Nakashima K, Araki R, Nakamura Y, Abe M, Tachibana M, Kimura H, Nifuji A.
- Organizer
  2015 ASCB Annual Meeting
- Place of Presentation
  San Diego Convention Center, San Diego, CA, USA
- Year and Date
  2015-12-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15679
[Presentation] iPS化における点突然変異生成タイミングの解析2015
- Author(s)
  砂山美里、安倍真澄、藤森（法喜）ゆう子、笠間康次、中村美樹、荒木良子
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25290068
[Presentation] A comparison of point mutations between iPS and ntES cell with whole genome sequencing2015
- Author(s)
  Yuko Fujimori-Hoki, Ryoko Araki, Misato Sunayama, Eiji Mizutani, Sayaka Wakayama, Hiroaki Nagatomo, Yasuji Kasama, Miki Nakamura, Teruhiko Wakayama, Masumi Abe
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25290068
[Presentation] Deletion of G9a, histone methyltransferase, causes impaired bone formation.2015
- Author(s)
  Ideno H, Komatsu K, Shimada A, Kamiunten T, Arai Y, Nakashima K, Araki R, Nakamura Y, Abe M, Tachibana M, Kimura H, Nifuji A
- Organizer
  ASM 2015, Joint ANZBMS, MEPSA and MBSANZ Annual Scientific Meeting
- Place of Presentation
  Hotel Grand Chancellor Hobart,Tasmania, Australia
- Year and Date
  2015-11-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15679
[Presentation] Point mutations in ES cells2013
- Author(s)
  砂山美里、杉浦真由美、法喜ゆう子、笠間康次、宇田昌広、中村美樹、安藤俊輔、荒木良子、安倍真澄
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25290068
[Presentation] iPS cells generation-associated point mutations2013
- Author(s)
  荒木良子、杉浦真由美、笠間康次、砂山美里、宇田昌広、安藤俊輔、中村美樹、法喜ゆう子、安倍真澄
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25290068
[Presentation] POINT MUTATIONS IN ES CELLS2013
- Author(s)
  Yuko Hoki, Mayumi Sugiura, Yasuji Kasama, Misato Sunayama, Masahiro Uda, Miki Nakamura, Shunsuke Ando, Ryoko Araki, Masumi Abe
- Organizer
  Society for Stem Cell Research-ISSCR 11th Annual Meeting
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-25290068
[Presentation] iPS cells generation-associated point mutations2013
- Author(s)
  Ryoko Araki, Mayumi Sugiura, Yasuji Kasama, Misato Sunayama, Masahiro Uda, Miki Nakamura, Shunsuke Ando, Yuko Hoki, Masumi Abe
- Organizer
  International Society for Stem Cell Research-ISSCR 11th Annual Meeting
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-25290068
[Presentation] MyoD mediated myogenic conversion from fibroblasts into myoblasts is blocked by cell cycle inhibition2013
- Author(s)
  Hisashi Ideno, Kazuhisa Nakashima, Yasuyuki Ohkawa, Hiroshi Kimura , Ryoko Araki , Masumi Abe , Akira Nifuji
- Organizer
  第３６回　日本分子生物学会
- Place of Presentation
  神戸国際会議場　兵庫県
- Data Source
  KAKENHI-PROJECT-25670784
[Presentation] Limited and comparable immunogenicity of terminally differentiated cells derived from both iPSCs and ESCs2012
- Author(s)
  Uda M, Araki R, Hoki Y, Sayama M, Nakamura M, Andou S, Sugiura M, IdenoH, Shimada A, Nifuji A, Abe M.
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場、福岡
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-23659862
[Presentation] MyoD-induced myogenic conversion requires cell proliferation2012
- Author(s)
  出野尚、中島和久、荒木良子、今泉和彦、二藤彰
- Organizer
  第67回日本体力医学会大会
- Place of Presentation
  長良川国際会議場岐阜
- Year and Date
  2012-09-14
- Data Source
  KAKENHI-PROJECT-23659862
[Presentation] Region-specific CpG demethylation patterns of the myogenin promoter isrequired for MyoD mediated myogenic conversion from fibroblasts into myoblasts2012
- Author(s)
  Ideno H, Nakashima K, Imaizumi K, Kasama Y, Araki R, Abe M, Nifuji A.
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場、福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-23659862
[Presentation] TSAによるmyogeninプロモーター脱メチル化制御を介した筋芽細胞への分化転換の抑制2012
- Author(s)
  出野尚、中島和久、荒木良子、今泉和彦、安倍真澄、二藤彰
- Organizer
  第30回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル、東京
- Year and Date
  2012-07-20
- Data Source
  KAKENHI-PROJECT-23659862
[Presentation] DNAメチル化阻害剤とHDAC 阻害剤による筋細胞分化制御2011
- Author(s)
  出野尚、荒木良子、今泉和彦、安倍真澄、二藤彰
- Organizer
  第66回体力医学会大会
- Place of Presentation
  下関市海峡メッセ,山口
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-23659862
[Presentation] The myogenic conversion from fibroblasts into myogenic cells is blocked by Trichostatin A through suppression of myogenin expression2011
- Author(s)
  Ideno H, Araki R,Imaizumi K, Abe M, Nifuji A.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜会議センター、神奈川
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-23659862
[Presentation] BMP antagonist PRDCの発現抑制による骨形成の促進2009
- Author(s)
  出野尚、荒木良子、今泉和彦、安倍真澄、二藤彰
- Organizer
  第64回体力医学会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-19390475
[Presentation] The BMP antagonist PRDC promotes ALP activity in the absence of BMP2009
- Author(s)
  出野尚、荒木良子、今泉和彦、安倍真澄、二藤彰
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390475
[Presentation] 骨芽細胞分化の抑制・促進双方に働くBMP antagonist PRDCの機能2009
- Author(s)
  出野尚、荒木良子、安倍真澄、二藤彰
- Organizer
  第27回骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390475
[Presentation] Masumi Abe Coordinate expression of multiple transcripts containing fragments of Line-1 retrotranposons during skeletal cell differentiation2009
- Author(s)
  Akira Nifuji, Hisashi Ideno, Ryoko Araki
- Organizer
  The 31st meeting of the American Society for Bone and Mineral Research (ASBMR)
- Place of Presentation
  Denver Co
- Data Source
  KAKENHI-PROJECT-19390475
[Presentation] 骨再生を目指したプラスミドDNAによる頭蓋骨欠損修復モデルの確立2008
- Author(s)
  荒木香映子
- Organizer
  第21回日本歯科医学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390475
[Presentation] BMP抑制分子PRDCの骨芽細胞分化における発現、制御とその機能2007
- Author(s)
  出野尚, 高鍋利依子, 荒木良子, 安倍真澄, 二藤彰
- Organizer
  第25回日本骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390475
[Presentation] Protein Related to DAN and Cerberus(PRDC)is expressed in skeletogenesis and prevents osteoblastic differentiation2007
- Author(s)
  Nifuji A, Ideno H, Takanabe R, Shimada A, Araki R, Abe M
- Organizer
  The 29th meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Honolulu
- Data Source
  KAKENHI-PROJECT-19390475
[Presentation] Protein Related to DAN and Cerberus (PRDC) is expressed in skeletogenesis and prevents osteoblastic differentiation2007
- Author(s)
  Nifuji A, Ideno H, Takanabe R, Shimada A, Araki R, Abe M
- Organizer
  The 29th meeting of the American Society for Bone and Mineral Research (ASBMR)
- Place of Presentation
  Honolulu, Hawaii
- Data Source
  KAKENHI-PROJECT-19390475
[Presentation] iPS樹立初期過程には多くのpoint mutationが生じる
- Author(s)
  藤森　ゆう子, 杉浦真由美, 笠間康次, 砂山美里, 宇田昌広, 中村美樹, 荒木良子, 安倍真澄.
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25290068
[Presentation] Lineage conversion step in iPS cell generation involves highly mutagenic process.
- Author(s)
  Ryoko Araki, Yuko Fujimori, Misato Sunayama, Yasuji Kasama, Masahiro Uda, Miki Nakamura, Masumi Abe.
- Organizer
  第12回国際幹細胞学会(ISSCR)年会
- Place of Presentation
  バンクーバー、カナダ
- Year and Date
  2014-06-18 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-25290068
[Presentation] iPS細胞クローン内細胞にみられるポイントミューテーションの不均一性
- Author(s)
  砂山　美里，荒木良子，藤森　ゆう子, 笠間康次,　宇田昌広, 中村美樹, 安倍真澄.
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25290068
[Presentation] Functions of histone methyltransferase G9a during growth and differentiation of mesenchymal cells
- Author(s)
  Ideno H1,4, Shimada A1, Kamiunten T2, Wada S2, Komatsu K1, Tachibana M3, Araki R4, Nakamura Y2, Abe M4, Nakashima K1, Nifuji A1,4
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25670784
[Presentation] The myogenic conversion from fibroblasts into myogenic cells is blocked by Trichostatin A through suppression of myogenin expression
- Author(s)
  Hisashi Ideno、Ryoko Araki、Kazuhiko Imaizumi、Masumi Abe、Akira Nifuji
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  神奈川県　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23659862
[Presentation] The functions of histone methyltransferase G9a during growth and differentiation of mesenchymal cells
- Author(s)
  出野尚1,4, 島田明美1, 上運天太一2, 和田悟史2, 小松浩一郎1, 立花誠3, 荒木良子4, 中村芳樹2, 安倍真澄4, 中島和久1,二藤彰1,4
- Organizer
  第56回歯科基礎医学会
- Place of Presentation
  福岡国際会議場（福岡県）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25670784
[Presentation] ES CELLS VS. IPS CELLS: LINEAGE CONVERSION-ASSOCIATED POINT MUTATIONS.
- Author(s)
  Yuko Fujimori, Mayumi Sugiura, Yasuji Kasama, Misato Sunayama, Masahiro Uda, Miki Nakamura, Shunsuke Ando, Ryoko Araki, Masumi Abe.
- Organizer
  第12回国際幹細胞学会(ISSCR)年会
- Place of Presentation
  バンクーバー、カナダ
- Year and Date
  2014-06-18 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-25290068
[Presentation] 間葉系細胞の増殖・分化過程におけるヒストンメチル化酵素G9aの機能
- Author(s)
  出野尚1,2, 島田明美1, 上運天太一3, 和田悟史3, 小松浩一郎1, 中島和久1, 荒木良子2, 安倍真澄2, 二藤彰1,2
- Organizer
  第32回　日本骨代謝学会
- Place of Presentation
  大阪国際会議場（大阪府）
- Year and Date
  2014-07-24 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-25670784

1. NIFUJI Akira (00240747)

# of Collaborated Projects: 4 results

# of Collaborated Products: 25 results
2. NAKASHIMA Kazuhisa (90252692)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
3. SHIBATA Tatsuya (90323708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. FUJIMORI YUKO (50415402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
5. SUNAYAMA MISATO (20625115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
6. SUGIURA MAYUMI (60397841)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
7. UDA MASAHIRO (30625893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
8. IDENO Hisashi (40435699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 江面陽一 (50333456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 島田明美 (00339813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. SHIBATA Norito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. NAKAMURA Yoshiki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 藤森亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 中島徹夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 上村悟氏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Araki Ryoko 荒木 良子

ARAKI Ryoko 荒木 良子

荒木 良子 アラキ リョウコ

Research Projects

Research Products

Co-Researchers

Reduction of genome reprogramming-associated mutationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Reprogramming associated point mutations and ROSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of genome-wide method for analyzing radiation effectsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search for molecular signatures that discriminate between tendon and ligament tissue

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genome instability during genome reprogrammingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cellular conversion from non- skeletal to skeletal cells by using transactivation MyoD domain

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Epigenetic changes in cell fate decision during mesenchymal cell differentiation.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular approaches to identify molecules involved in the cell aggregates formation in the skeletal blastema and elucidation of their functional properties

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 日本臨床 増刊号 再生医療 「iPS化に伴う点突然変異」2015

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Insertion/deletion and microsatellite alteration profiles in induced pluripotent stem cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In situ delivery of iPSC-derived dendritic cells with local radiotherapy generates systemic antitumor immunity and potentiates PD-L1 blockade in preclinical poorly immunogenic tumor models2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic aberrations in iPSCs are introduced by a transient G1/S cell cycle checkpoint deficiency2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Low and High LET Ionizing Radiation-Induced Delayed Homologous Recombination Persists for Two Weeks Before Resolving.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hotspots of De Novo Point Mutations in Induced Pluripotent Stem Cells2017

Araki Ryoko 荒木良子

ARAKI Ryoko 荒木良子

荒木良子アラキリョウコ

[Book] 日本臨床　増刊号　再生医療「iPS化に伴う点突然変異」2015