OHTA Hikoto 太田彦人

Researcher Number	40392261
Other IDs
Affiliation (Current)	2023: 科学警察研究所, 法科学第三部, 室長
Affiliation (based on the past Project Information) *help	2013 – 2021: 科学警察研究所, 法科学第三部, 室長 2005 – 2006: National Research Institute of Police Science, Third Forensic Science, Senior researcher, 法科学第三部, 主任研究官
Review Section/Research Field	Principal Investigator Emergency medicine / Living organism molecular science / Basic Section 55060:Emergency medicine-related Except Principal Investigator Emergency medicine / Environmental and hygienic pharmacy
Keywords	Principal Investigator MS / アセチルコリンエステラーゼ / 脳内活性回復 / 4-PAO / 2-PAM / サリン類似体 / サリン阻害ラット / AChE活性測定 / MATP+ / 救急蘇生学 … More / 有機リン中毒 / 神経剤 / 解毒剤 / 血液脳関門 / オキシム / アルカロイド / トリカブト / アコニチン / 代謝物 / バイケイソウ / 生体試料 / LC-ESI-MS / 分析 / ジェサコニチン / Alkaloid / Aconite / Aconitine / Metabolite / Veratrum / Human fluid / LC-MS / Analysis / 自然毒 / 中毒 / 高感度LC-MS/MS一斉検出 / スペクトルデータベース / 毒草 / 毒キノコ / 毒魚 / QuEChERS / カエンタケ / 自然毒中毒 / 中毒原因特定 / 救命救急医療 / LC-MS/MS / 網羅的自動検出 … More Except Principal Investigator 2-PAM / Sarin / INMP / BBB / 4-PAO / cardiac effect / ECG / actomyosin / ATPase / 神経ガス / オキシム / パム / VX / Soman / 生物種判別 / 高分解能質量分析 / モノアイソトピック質量 / フグ / ドクゼリ / モノリスカラム / DNA / 液体クロマトグラフィー／高分解能質量分析 / セリ / 質量分析 / 種判別 Less

Development of novel screening technique for the rapid identification of poisoning cause for the emergency and critical care of the natural toxin poisoning casesPrincipal Investigator
- Principal Investigator
  
  太田彦人
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  National Research Institute of Police Science
Genotyping of Toxic Animals and Plants by Liquid Chromatography/High Resolution Mass Spectrometry
- Principal Investigator
  
  Miyaguchi Hajime
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  National Research Institute of Police Science
A novel detoxification treatment for organophosphorus poisoning by using BBB penetrative oximesPrincipal Investigator
- Principal Investigator
  
  Ohta Hikoto
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  National Research Institute of Police Science
Investigation of the toxic mechanism of oximes which are used in the treatment of poisoning by nerve agents
- Principal Investigator
  
  SAKURADA Koichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  National Research Institute of Police Science
Studies on isolation, synthesis and analysis of toxic plant terpenoidsPrincipal Investigator
- Principal Investigator
  
  OHTA Hikoto
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  National Research Institute of Police Science
Study of a new antidote for nerve gas poisoning brought by chemical terrorism
- Principal Investigator
  
  TAKATRI Takehiko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Emergency medicine
- Research Institution
  National Research Institute of Police Science

All 2021 2020 2019 2018 2017 2016 2015 2014 2012

All Journal Article Presentation

[Journal Article] Toxicological analysis of satratoxins, the main toxins in the mushroom Trichoderma cornu-damae, in human serum and mushroom samples by liquid chromatography?tandem mass spectrometry2021
- Author(s)
  Koichi Sakurada, Hikoto Ohta
- Journal Title
  
  Forensic Toxicology
  
  Volume: 47 Pages: 101761-101761
- DOI
  10.1007/s11419-020-00549-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09428
[Journal Article] Development of micro-spectroscopic system and its application to single fibers2021
- Author(s)
  Watanabe Daisuke、Ohta Hikoto、Sakayanagi Masataka
- Journal Title
  
  Japanese Journal of Forensic Science and Technology
  
  Volume: 26 Issue: 1 Pages: 129-135
- DOI
  10.3408/jafst.783
- NAID
  130007978459
- ISSN
  1880-1323, 1881-4689
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K04996, KAKENHI-PROJECT-19K09428
[Journal Article] Long-term decomposition and diffusion of glyphosate and glufosinate in soil2020
- Author(s)
  Daisuke Watanabe, Yuko Kazui, Hikoto Ohta
- Journal Title
  
  Japanese Journal of Forensic Science and Technology
  
  Volume: 25(1) Issue: 1 Pages: 15-21
- DOI
  10.3408/jafst.762
- NAID
  130007792842
- ISSN
  1880-1323, 1881-4689
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09428
[Journal Article] A rapid screening color test for glyphosate using dabsyl derivatization2019
- Author(s)
  Watanabe Daisuke、Kazui Yuko、Ohta Hikoto
- Journal Title
  
  Forensic Toxicology
  
  Volume: 37 Pages: 443-448
- DOI
  10.1007/s11419-018-00460-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09428
[Journal Article] Rapid and robust speciation/quantitative analysis of arsenous acid and related metabolites in serum by liquid chromatography - inductively coupled plasma-tandem mass spectrometry2019
- Author(s)
  Kazui Yuko、Ohta Hikoto、Watanabe Daisuke、Igawa Takao、Kasamatsu Masaaki、Suzuki Yasuhiro、Seto Yasuo
- Journal Title
  
  Forensic Toxicology
  
  Volume: 37 Pages: 424-431
- DOI
  10.1007/s11419-019-00479-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09428
[Journal Article] Analysis of toxic Veratrum alkaloids in plant samples from an accidental poisoning case2018
- Author(s)
  Minatani Tomiaki, Ohta Hikoto, Sakai Eiji, Tanaka Toshiyuki, Goto Kotaro, Watanabe Daisuke, Miyaguchi Hajime
- Journal Title
  
  Forensic Toxicology
  
  Volume: 36 Pages: 200-210
- DOI
  10.1007/s11419-017-0390-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08060
[Journal Article] The Forgotten or Underestimated Relevance of Biopharmaceutical-Based Assessments for the Oral Absorption Studies of Oxime Reactivators2016
- Author(s)
  Victor A. Voicu, Andrei Valentin Medvedovici, Koichi Sakurada, Hikoto Ohta, Flavian Stefan Radulescu, Dalia Simona Miron
- Journal Title
  
  Expert Opinion on Drug Metabolism and Toxicology
  
  Volume: 12(7) Pages: 743-752
- DOI
  10.1080/17425255.2016.1179282
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462845
[Journal Article] Genotyping of toxic pufferfish based on specific PCR-RFLP products as determined by liquid chromatography/quadrupole-Orbitrap hybrid mass spectrometry2015
- Author(s)
  Hajime Miyaguchi, Tadashi Yamamuro, Hikoto Ohta, Hiroaki Nakahara, Shinichi Suzuki
- Journal Title
  
  Journal of Agricultural and Food Chemistry
  
  Volume: 63 Pages: 9363-9371
- DOI
  10.1021/acs.jafc.5b03703
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08060
[Journal Article] Lipophilicity indices derived from the liquid chromatographic behavior observed under bimodal retention conditions (reversed phase/hydrophilic interaction): Application to a representative set of pyridinium oximes2014
- Author(s)
  Victor Voicu, Costel Sârbu, Florentin Tache, Florina Micăle,Ştefan F. Rădulescu, Koichi Sakurada, Hikoto Ohta, Andrei Medvedovici
- Journal Title
  
  Talanta
  
  Volume: Vol.122 Pages: 172-179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592690
[Journal Article] Lipophilicity indices derived from the liquid chromatographic behavior observed under bimodal retention conditions (reversed phase/hydrophilic interaction): application to a representative set of pyridinium oximes2014
- Author(s)
  Victor Voicu, Costel Sarbu, Florentin Tache, Florina Micale, Stefan Flavian Radulescu, Koichi sakurada, Hikoto Ohta, Andrei Medvedovici
- Journal Title
  
  Talanta
  
  Volume: 122 Pages: 172-179
- DOI
  10.1016/j.talanta.2014.01.048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592690, KAKENHI-PROJECT-25462845
[Presentation] Fun of natural toxin analysis - Attractiveness of complex and miraculous chemical structures2021
- Author(s)
  Hikoto Ohta
- Organizer
  27th Annual Meeting of Japanese Association of Forensic Science and Technology
- Invited
- Data Source
  KAKENHI-PROJECT-19K09428
[Presentation] Development of techniques for combating poisoning cases2021
- Author(s)
  Hikoto Ohta
- Organizer
  14th United Nations Congress on Crime Prevention and Criminal Justice (Kyoto Congress 2020)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09428
[Presentation] 水溶性除草剤の直接一斉分析法の開発2021
- Author(s)
  渡邉大助，園田修平，太田彦人
- Organizer
  日本法科学技術学会第27回学術集会
- Data Source
  KAKENHI-PROJECT-19K09428
[Presentation] カエンタケ毒の分析2019
- Author(s)
  太田彦人, 渡邉大助, 野村千枝
- Organizer
  日本法中毒学会第38年会
- Data Source
  KAKENHI-PROJECT-19K09428
[Presentation] LC/MSを用いた塩基組成解析によるセリとドクゼリの種判別2017
- Author(s)
  宮口一，山室匡史，渡邉大助，太田彦人
- Organizer
  日本法科学技術学会　第２３回学術集会
- Data Source
  KAKENHI-PROJECT-15K08060
[Presentation] Rapid genotyping of Oenanthe javanica and Cicuta virosa by polymerase chain reaction followed by liquid chromatography/high-resolution mass spectrometry2017
- Author(s)
  Hajime Miyaguchi, Tadashi Yamamuro, Daisuke Watanabe, Hikoto Ohta
- Organizer
  65th Conference on Mass Spectrometry and Allied Topics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08060
[Presentation] 液体クロマトグラフィー／質量分析によるオリゴヌクレオチドの迅速分析法の開発と生物種判別への応用2016
- Author(s)
  宮口　一，山室匡史，太田彦人，中原弘明，鈴木真一
- Organizer
  第14回表示・起源分析技術研究懇談会講演会
- Place of Presentation
  柏の葉カンファレンスセンター
- Year and Date
  2016-01-26
- Data Source
  KAKENHI-PROJECT-15K08060
[Presentation] 液体クロマトグラフィー／高分解能質量分析によるPCR-RFLP法の開発とフグ種判別への応用2015
- Author(s)
  宮口　一，山室匡史，太田彦人，中原弘明，鈴木真一
- Organizer
  日本DNA多型学会第24回学術集会
- Place of Presentation
  岡山大学創立五十周年記念館
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-15K08060
[Presentation] Effect of Side-Chain Elongation of Pyridinealdoxime Methiodide-Type Acetylcholinesterase Reactivators on Blood-Brain Barrier Penetration2014
- Author(s)
  H. Ohta, T. Yamamuro, K. Sakurada
- Organizer
  The 52nd Annual Meeting of TIAFT
- Place of Presentation
  Buenos Aires, Argentine
- Year and Date
  2014-11-12
- Data Source
  KAKENHI-PROJECT-25462845
[Presentation] Development of BBB-penetrative antidotes for reactivation of inhibited AChE in nerve agent poisoning2012
- Author(s)
  Hikoto Ohta and Koichi Sakurada
- Organizer
  2012 International Congress of the Romanian Society of Pharmacology, Therapeutics and Clinical Toxicology
- Place of Presentation
  Bucharest in Romania
- Invited
- Data Source
  KAKENHI-PROJECT-23592690
[Presentation] Development of BBB-penetrative antidotes for reactivation of inhibited AChE in nerve agent poisoning2012
- Author(s)
  Hikoto Ohta and Koichi Sakurada
- Organizer
  13^<th> International Congress of the Romanian Society of Pharmacology, Therapeutics and Clinical Toxicology
- Data Source
  KAKENHI-PROJECT-23592690

1. SAKURADA Koichi (10334228)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. Miyaguchi Hajime (10370884)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. YAMAMURO Tadashi (80646555)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. TAKATRI Takehiko (30001928)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YASUDA Jiro (10282518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OHTSURU Osamu (60356194)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OHTA Hikoto 太田 彦人

Research Projects

Research Products

Co-Researchers

Development of novel screening technique for the rapid identification of poisoning cause for the emergency and critical care of the natural toxin poisoning casesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genotyping of Toxic Animals and Plants by Liquid Chromatography/High Resolution Mass Spectrometry

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A novel detoxification treatment for organophosphorus poisoning by using BBB penetrative oximesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of the toxic mechanism of oximes which are used in the treatment of poisoning by nerve agents

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on isolation, synthesis and analysis of toxic plant terpenoidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of a new antidote for nerve gas poisoning brought by chemical terrorism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Toxicological analysis of satratoxins, the main toxins in the mushroom Trichoderma cornu-damae, in human serum and mushroom samples by liquid chromatography?tandem mass spectrometry2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of micro-spectroscopic system and its application to single fibers2021

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Long-term decomposition and diffusion of glyphosate and glufosinate in soil2020

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] A rapid screening color test for glyphosate using dabsyl derivatization2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rapid and robust speciation/quantitative analysis of arsenous acid and related metabolites in serum by liquid chromatography - inductively coupled plasma-tandem mass spectrometry2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of toxic Veratrum alkaloids in plant samples from an accidental poisoning case2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Forgotten or Underestimated Relevance of Biopharmaceutical-Based Assessments for the Oral Absorption Studies of Oxime Reactivators2016

Author(s)

Journal Title

DOI

OHTA Hikoto 太田彦人