UTSUGI Mitsuyoshi 宇津木光克

Researcher Number	40396635
Affiliation (based on the past Project Information) *help	2010: Gunma University, 医学部, その他 2005 – 2009: 群馬大学, 医学部, 医員
Review Section/Research Field	Principal Investigator 膠原病・アレルギー・感染症内科学
Keywords	Principal Investigator シグナル伝達 / 樹状細胞 / レドックス / Th2 / Th1 / Interleukin-12 / 抗原提示細胞 / IL-12 / サイトカイン / TH1

Research Projects
(3 results)
Research Products
(12 results)

レドックスによるヒト抗原提示細胞の機能修飾:IL-27産生を介したTh17制御Principal Investigator
- Principal Investigator
  
  宇津木光克
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Gunma University
JNK1 and JNK2 differently regulate IL-12 productionPrincipal Investigator
- Principal Investigator
  
  UTSUGI Mitsuyoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Gunma University
樹状細胞を用いたアレルギー疾患治療の基礎的研究:レドックス制御を基盤とした検討Principal Investigator
- Principal Investigator
  
  宇津木光克
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Gunma University

All 2009 2008 2007 2006

All Journal Article Presentation

[Journal Article] 抗原提示細胞とアレルギー2009
- Author(s)
  宇津木光克
- Journal Title
  
  日本臨床 67巻
  
  Pages: 2076-2081
- Data Source
  KAKENHI-PROJECT-21790938
[Journal Article] Glutathione redox regulates TGF-beta-induced fibrogenic effects through Smad3 activation2009
- Author(s)
  Akihiro Ono, Mitsuyoshi Utsugi, et.al.
- Journal Title
  
  FEBS letters 583
  
  Pages: 357-362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790680
[Journal Article] Glutathione redox regulates TGF-beta-induced fibrogenic effects through Smad3 activation2009
- Author(s)
  Akihiro Ono、Mitsuyoshi Utsugi、Ken Masubuchi(他7名2番目)
- Journal Title
  
  FEBS Letters 583巻
  
  Pages: 357-362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790680
[Journal Article] PI3K p110beta positively regulates LPS-induced IL-12 production in human macrophages and dendritic cells and JNK1 plays a novel role2009
- Author(s)
  Mitsuyoshi Utsugi、Kunio Dobashi、Akihiro Ono(他8名1番目)
- Journal Title
  
  Journal of Immunology 182巻
  
  Pages: 5225-5231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790680
[Journal Article] PI3K p11013 positively regulates LPS-induced IL-12 productior in human macrophages and dendritic cells and JNK1 plays a novel role2009
- Author(s)
  Mitsuyoshi Utsugi, et.al.
- Journal Title
  
  Journal of Immunology (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790680
[Journal Article] Racl negatively regulates lipopolysaccharide-induced IL-23 p19 expression in human macrophages and dendritic cells and NF-kappaB p65 trans activation plays a novel role.2006
- Author(s)
  Utsugi M.
- Journal Title
  
  Journal of Immunology 177(7)
  
  Pages: 4550-4557
- Data Source
  KAKENHI-PROJECT-17790667
[Presentation] 臨床・研究のための技術・機能プラクティカルセミナー3 ヒト樹状細胞2009
- Author(s)
  宇津木光克
- Organizer
  第59回日本アレルギー学会秋季学術大会
- Place of Presentation
  秋田アトリオン
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-21790938
[Presentation] ヒトマクロファージ樹状細胞からのIL-12産生1さPI3K p110βの正の制御を受ける2008
- Author(s)
  宇津木光克
- Organizer
  第58回日本アレルギー学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2008-11-27
- Data Source
  KAKENHI-PROJECT-19790680
[Presentation] ヒトマクロファージ・樹状細胞からのIL-12産生はPI3K p110betaによる正の制御を受ける2008
- Author(s)
  宇津木光克
- Organizer
  第58回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Year and Date
  2008-11-27
- Data Source
  KAKENHI-PROJECT-19790680
[Presentation] PI3K p110beta positively regulates LPS-induced IL-12 production in human macrophages and dendritic cells and JNK1 plays a novel role2008
- Author(s)
  宇津木光克
- Organizer
  第38回日本免疫学会総会
- Place of Presentation
  京都
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-19790680
[Presentation] JNK isoformによるヒトマクロファージからの異なったIL-12産生制御2007
- Author(s)
  宇津木光克
- Organizer
  第57回日本アレルギー学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-11-01
- Data Source
  KAKENHI-PROJECT-19790680
[Presentation] JNK isoformによるヒトマクロファージからの異なったIL-12産生制御2007
- Author(s)
  宇津木光克
- Organizer
  第57回日本アレルギー学会秋季学術大会
- Place of Presentation
  横浜
- Year and Date
  2007-11-01
- Data Source
  KAKENHI-PROJECT-19790680

UTSUGI Mitsuyoshi 宇津木 光克

Research Projects

Research Products

レドックスによるヒト抗原提示細胞の機能修飾:IL-27産生を介したTh17制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

JNK1 and JNK2 differently regulate IL-12 productionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

樹状細胞を用いたアレルギー疾患治療の基礎的研究:レドックス制御を基盤とした検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 抗原提示細胞とアレルギー2009

Author(s)

Journal Title

Data Source

[Journal Article] Glutathione redox regulates TGF-beta-induced fibrogenic effects through Smad3 activation2009

Author(s)

Journal Title

Data Source

[Journal Article] Glutathione redox regulates TGF-beta-induced fibrogenic effects through Smad3 activation2009

Author(s)

Journal Title

Data Source

[Journal Article] PI3K p110beta positively regulates LPS-induced IL-12 production in human macrophages and dendritic cells and JNK1 plays a novel role2009

Author(s)

Journal Title

Data Source

[Journal Article] PI3K p11013 positively regulates LPS-induced IL-12 productior in human macrophages and dendritic cells and JNK1 plays a novel role2009

Author(s)

Journal Title

Data Source

[Journal Article] Racl negatively regulates lipopolysaccharide-induced IL-23 p19 expression in human macrophages and dendritic cells and NF-kappaB p65 trans activation plays a novel role.2006

Author(s)

Journal Title

Data Source

[Presentation] 臨床・研究のための技術・機能プラクティカルセミナー3 ヒト樹状細胞2009

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ヒトマクロファージ樹状細胞からのIL-12産生1さPI3K p110βの正の制御を受ける2008

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ヒトマクロファージ・樹状細胞からのIL-12産生はPI3K p110betaによる正の制御を受ける2008

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] PI3K p110beta positively regulates LPS-induced IL-12 production in human macrophages and dendritic cells and JNK1 plays a novel role2008

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] JNK isoformによるヒトマクロファージからの異なったIL-12産生制御2007

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] JNK isoformによるヒトマクロファージからの異なったIL-12産生制御2007

Author(s)

Organizer

Place of Presentation

Year and Date

UTSUGI Mitsuyoshi 宇津木光克