HYOGO Hideyuki 兵庫秀幸

Researcher Number	40397930
Affiliation (based on the past Project Information) *help	2015: 広島大学, 大学病院, 助教 2015: 広島大学, 学内共同利用施設等, 助教 2015: 広島大学, 病院(医), 病院助教 2013 – 2014: 広島大学, 大学病院, 病院助教
Review Section/Research Field	Except Principal Investigator Metabolomics / Morphological basic dentistry
Keywords	Except Principal Investigator ターゲット・リシークエンス / PNPLA3 / メチル化 / メチル化DNA / RNAシークエンス / メタボリックシンドローム / 遺伝子多型 / エピゲノム / 次世代シークエンサー / 内臓脂肪蓄積 … More / 非アルコール性脂肪肝疾患 / 肝障害 / porphyromonas gingivalis / 肝癌 / 肝線維化 / 歯周病 / NASH / 全身疾患 / TGFβ / TLR2 / LPS / 肝星細胞 / 線維化 / 非アルコール性脂肪性肝炎 / Galectin-3 / Porphyromonas gingivalis / 歯性感染 Less

Study on pathological progression mechanisms of non-alcoholic steatohepatitis caused by odontogenic infection of periodontal pathogen
- Principal Investigator
  
  Miyauchi Mutsumi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hiroshima University
The search and prospective follow-up study of genetic predisposition and environmental factors of ectopic fat accumulation
- Principal Investigator
  
  Hotta Kikuko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Osaka University
  Kyoto University

All 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Influence of the rs738409 polymorphism in patatin-like phospholipase 3 on the treatment efficacy of non-alcoholic fatty liver disease with type 2 diabetes mellitus.2016
- Author(s)
  Kan H, Hyogo H, Ochi H, Hotta K, Fukuhara T, Kobayashi T, Naeshiro N, Honda Y, Kawaoka T, Tsuge M, Hiramatsu A, Imamura M, Kawakami Y, Aikata H, Chayama K
- Journal Title
  
  Hepatol Res
  
  Volume: 46 Issue: 3 Pages: 146-153
- DOI
  10.1111/hepr.12552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461343
[Journal Article] <i>CDH13</i> Polymorphisms are Associated with Adiponectin Levels and Metabolic Syndrome Traits Independently of Visceral Fat Mass2016
- Author(s)
  Kitamoto A, Kitamoto T, Nakamura T, Matsuo T, Nakata Y, Hyogo H, Ochi H, Kamohara S, Miyatake N, Kotani K, Mineo I, Wada J, Ogawa Y, Yoneda M, Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Masuzaki H, Ueno T, Chayama K, Hamaguchi K, Yamada K, Hanafusa T, Oikawa S, Sakata T, Tanaka K, Matsuzawa Y, Hotta K.
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 23 Issue: 3 Pages: 309-319
- DOI
  10.5551/jat.31567
- NAID
  130005131888
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461343
[Journal Article] The characteristics of non-obese NAFLD: Effect of genetic and environmental factors.2016
- Author(s)
  Honda Y, Yoneda M, Kessoku T, Ogawa Y, Tomeno W, Imajo K, Mawatari H, Fujita K, Hyogo H, Ueno T, Chayama K, Saito S, Nakajima A, Hotta K
- Journal Title
  
  Hepatol Res
  
  Volume: - Issue: 10 Pages: 636-636
- DOI
  10.1111/hepr.12648
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461343, KAKENHI-PROJECT-26860516, KAKENHI-PROJECT-15K19340, KAKENHI-PROJECT-16K09781, KAKENHI-PROJECT-16K19357
[Journal Article] <i>ADIPOQ</i> polymorphisms are associated with insulin resistance in Japanese women2015
- Author(s)
  KitamotoA, KitamotoT, SoR, MatsuoT, NakataY, HyogoH, OchiH, NakamuraT, KamoharaS, MiyatakeN, KotaniK, MineoI, WadaJ, OgawaY, YonedaM, NakajimaA, FunahashiT, MiyazakiS, TokunagaK, MasuzakiH, UenoT, ChayamaK, HamaguchiK, YamadaK, HanafusaT, OikawaS, SakataT, TanakaK, MatsuzawaY, HottaK.
- Journal Title
  
  Endocr J
  
  Volume: 62 Issue: 6 Pages: 513-521
- DOI
  10.1507/endocrj.EJ14-0574
- NAID
  130005085774
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460999, KAKENHI-PROJECT-26870290, KAKENHI-PROJECT-14F04009, KAKENHI-PROJECT-25461343
[Journal Article] Association of polymorphisms in GCKR and TRIB1 with nonalcoholic fatty liver disease and metabolic syndrome traits2014
- Author(s)
  Kitamoto A, Kitamoto T, Nakamura T, Ogawa Y, Yoneda M, Hyogo H, Ochi H, Mizusawa S, Ueno T, Nakao K, Sekine A, Chayama K, Nakajima A, Hotta K
- Journal Title
  
  Endocrine Journal
  
  Volume: 8
- NAID
  130004677938
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461343
[Journal Article] Targeted next-generation sequencing and fine linkage disequilibrium mapping reveals association of PNPLA3 and PARVB with the severity of nonalcoholic fatty liver disease2014
- Author(s)
  Kitamoto T, Kitamoto A, Yoneda M, Hyogo H, Ochi H, Mizusawa S, Ueno T, Nakao K, Sekine A, Chayama K, Nakajima A, Hotta K
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 6 Issue: 5 Pages: 241-6
- DOI
  10.1038/jhg.2014.17
- NAID
  120005477223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461343, KAKENHI-PROJECT-25670369, KAKENHI-PROJECT-25870378, KAKENHI-PROJECT-26670383
[Journal Article] Dental infection of Porphyromonas gingivalis exacerbates high fat diet-induced steatohepatitis in mice2013
- Author(s)
  FurushoH,Miyauchi M,Hyogo H,Inubushi T,Ao M,Ouhara K,Hisatune J,Kurihara H,Sugai M,Hayes CN,Nakahara T,Akikata H,Takahashi S,Chayama K,Takata T
- Journal Title
  
  J Gastroenterol
  
  Volume: 48(11) Issue: 11 Pages: 1259-70
- DOI
  10.1007/s00535-012-0738-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890138, KAKENHI-PROJECT-25462855, KAKENHI-PROJECT-25862051
[Presentation] 歯周病原細菌Porphyromonas gingivalis歯性感染はNASH病態を増悪する2014
- Author(s)
  宮内睦美，古庄寿子，兵庫秀幸，茶山一彰，栗原英見，髙田隆
- Organizer
  第10回広島肝臓プロジェクト研究センターシンポジウム
- Place of Presentation
  広島市
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-25462855
[Presentation] ウエスト：ヒップ比及びBMI感受性遺伝子多型の内臓脂肪および皮下脂肪面積に及ぼす効果2013
- Author(s)
  堀田紀久子、松尾知明、中田由夫、兵庫秀幸、越智秀典、蒲原聖可、小谷一晃、伊藤直人、嶺尾郁夫、和田淳、米田正人、中島淳、船橋徹、宮崎滋、徳永勝人、益崎裕章、茶山一彰、上野隆登、浜口和之、山田研太郎、花房俊昭、及川眞一、坂田利家、田中喜代次、松澤佑次、中尾一和
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-25461343
[Presentation] 非アルコール性脂肪肝疾患感受性領域の次世代シークエンサーによるターゲットリシークエンス
- Author(s)
  堀田紀久子,北本卓也,北本綾,兵庫秀幸,越智秀典,上野隆登,茶山一彰,米田正人,小川裕二,中島淳
- Organizer
  日本人類遺伝学会第59回大会
- Place of Presentation
  東京都江戸川区
- Year and Date
  2014-11-19 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-25461343
[Presentation] 非アルコール性脂肪肝炎感受性領域の次世代シークエンサーによるターゲットリシークエンス
- Author(s)
  堀田紀久子,北本綾,北本卓也,小川裕二,米田正人, 上野隆登,兵庫秀幸,越智秀典,茶山一彰,中島淳
- Organizer
  第57回日本糖尿病学会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25461343
[Presentation] Targeted next-generation sequencing and fine linkage disequilibrium mapping reveals association of PNPLA3 and PARVB with the severity of nonalcoholic fatty liver disease
- Author(s)
  Hotta K, Kitamoto T, Kitamoto A, Yoneda M, Hyogo H, Ochi H, Ueno T, Chayama K, Nakajima A
- Organizer
  th Metabolic Syndrome, Type 2 Diabetes and Atherosclerosis Congress
- Place of Presentation
  京都府京都市
- Year and Date
  2014-09-12 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-25461343
[Presentation] GCKR、TRIB1の遺伝子多型とメタボリックシンドローム及び非アルコール性脂肪肝疾患との関連
- Author(s)
  堀田紀久子,北本綾,北本卓也,小川裕二,米田正人, 上野隆登,兵庫秀幸,越智秀典,茶山一彰,中島淳
- Organizer
  第35回日本肥満学会
- Place of Presentation
  宮崎県宮崎市
- Year and Date
  2014-10-24 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-25461343

1. Miyauchi Mutsumi (50169265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. Furusho Hisako (00634461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. Takata Takashi (10154783)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. Inubushi Toshihiro (30550941)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Hotta Kikuko (30360639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
6. KITAMOAO Takuya (10456882)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. KITAMOAO Aya (30381627)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. YONEDA Masato (10423831)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results

HYOGO Hideyuki 兵庫 秀幸

Research Projects

Research Products

Co-Researchers

Study on pathological progression mechanisms of non-alcoholic steatohepatitis caused by odontogenic infection of periodontal pathogen

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The search and prospective follow-up study of genetic predisposition and environmental factors of ectopic fat accumulation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Influence of the rs738409 polymorphism in patatin-like phospholipase 3 on the treatment efficacy of non-alcoholic fatty liver disease with type 2 diabetes mellitus.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] <i>CDH13</i> Polymorphisms are Associated with Adiponectin Levels and Metabolic Syndrome Traits Independently of Visceral Fat Mass2016

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] The characteristics of non-obese NAFLD: Effect of genetic and environmental factors.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] <i>ADIPOQ</i> polymorphisms are associated with insulin resistance in Japanese women2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Association of polymorphisms in GCKR and TRIB1 with nonalcoholic fatty liver disease and metabolic syndrome traits2014

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Targeted next-generation sequencing and fine linkage disequilibrium mapping reveals association of PNPLA3 and PARVB with the severity of nonalcoholic fatty liver disease2014

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Dental infection of Porphyromonas gingivalis exacerbates high fat diet-induced steatohepatitis in mice2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] 歯周病原細菌Porphyromonas gingivalis歯性感染はNASH病態を増悪する2014

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ウエスト：ヒップ比及びBMI感受性遺伝子多型の内臓脂肪および皮下脂肪面積に及ぼす効果2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 非アルコール性脂肪肝疾患感受性領域の次世代シークエンサーによるターゲットリシークエンス

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 非アルコール性脂肪肝炎感受性領域の次世代シークエンサーによるターゲットリシークエンス

Author(s)

Organizer

Place of Presentation

Year and Date

HYOGO Hideyuki 兵庫秀幸