ENDO Motoyoshi 遠藤元誉

Researcher Number	40398243
Other IDs
Affiliation (Current)	2025: 産業医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2023: 産業医科大学, 医学部, 教授 2017: 熊本大学, 大学院生命科学研究部(医), 助教 2017: 熊本大学, 大学院生命科学研究部, 助教 2012 – 2015: 熊本大学, 大学院生命科学研究部, 助教 2009 – 2011: Kumamoto University, 大学院・生命科学研究部, 助教 … More 2008: Kumamoto University, 大学院・医学薬学研究部, 産学官連携研究員 2007: Kumamoto University, Dept. Mol. Genet., Grad. Sch. Med. Sci., Research Fellow 2006: 熊本大学, 大学院医学薬学研究部, 文部科研研究員 2006: Kumamoto Univ., Dept. Mol. Genet., Grad. Sch. Med. Sci., Research Fellow, 大学院医学薬学研究部, 研究員 2005: 熊本大学, 大学院・医学薬学研究部, 技術支援者 Less
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related / Pathological medical chemistry / Biological Sciences Except Principal Investigator Pathological medical chemistry / Tumor biology
Keywords	Principal Investigator 肺癌 / アポトーシス / CHOP / 小胞体ストレス / IL-1β / 癌浸潤・転移 / ANGPTL2 / マクロファージ / caspase-11 / パイロトーシス … More / Caspase / 肺腺癌 / カスパーゼ4 / RUNX1 / 癌幹細胞 / 組織修復 / basal stem cell / 組織幹細胞 / eR1 / 肺損傷 / 癌 / TET2 / IL-6 / c-Myc / miR-204-5p / ZEB1 / GLUT3 / 癌代謝 / neurotrophic factor / neuronal cell death / glutamic acid / inflammation / ER stress / 骨髄腫 / BiP / XBP-1 / LPS / 神経栄養因子 / 神経細胞死 / グルタミン酸 / 炎症 / カスパーゼ11 / ブレオマイシン / 肺線維症 / ブレオマイシン肺臓炎 / Angptl2 / 間質性肺炎 / 慢性炎症 / 発癌 / サイトカイン / Angpt12 / 低酸素・低栄養 / アンジオポエチン様因子 / 浸潤・転移 / 血管新生因子 / 血管新生 / 転移 / ERAD / 呼吸器病学 … More Except Principal Investigator CHOP / 炎症 / 小胞体ストレス / IL-1β / BiP / LPS / 小胞体ストレスセンサー / アポトーシス / マクロファージ / がん制御遺伝子 / 転座 / 希少がん / 骨肉腫 / 腎細胞がん / がん微小環境 / 転写制御 / 稀少がん / apoptosis / inflammation / ILPS / caspase-1 / caspase-11 / ER stress / サイトカイン / カスパーセ11 / カスパーゼ11 / ミトコンドリアストレス / 活性酸素 / ゴルジ体 / 細胞酸素消費速度 / 細胞内小器官 / 細胞内ストレス応答 / 虚血再灌流障害 / ミトコンドリア / ストレス応答 / 細胞小器官 / 小胞体 / XBP-1 / コレステロール / 遊離コレステロール / プラーク不安定化 / 動脈硬化 Less

Elucidation of the function of inflammatory caspases in lung cancer progressionPrincipal Investigator
- Principal Investigator
  
  遠藤元誉
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Development of novel lung injury therapies based on the regulation of lung tissue stem cellsPrincipal Investigator
- Principal Investigator
  
  Endo Motoyoshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  University of Occupational and Environmental Health, Japan
The research for developing a method for controlling cancer invasion and metastasis by elucidating the mechanism of cancer metabolic changePrincipal Investigator
- Principal Investigator
  
  Endo Motoyoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Occupational and Environmental Health, Japan
  Kumamoto University
Elucidation of molecular mechanisms underlying development and progression of rare cancers caused by alteration of transcriptional regulation
- Principal Investigator
  
  Kadomatsu Tsuyoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Kumamoto University
The role of Angptl2 expression in lung for interstitial pneumoniaPrincipal Investigator
- Principal Investigator
  
  Endo Motoyoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kumamoto University
新規炎症関連因子ＡＮＧＰＴＬ２による癌の発症・浸潤・転移の分子機構解明Principal Investigator
- Principal Investigator
  
  遠藤元誉
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
Involvement of ER stress pathway in chronic inflammatory diseases.
- Principal Investigator
  
  GOTOH TOMOMI
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
Functional analysis of the ER stress response in the development of lung cancer metastasisPrincipal Investigator
- Principal Investigator
  
  ENDO Motoyoshi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kumamoto University
Analysis of the pathological roles of ER stress-induced transcriptional factors
- Principal Investigator
  
  GOTOH Tomomi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
The study of ER stress pathway and inflammationPrincipal Investigator
- Principal Investigator
  
  ENDO Motoyoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kumamoto University
Pathological roles of ER stress pathway in inflammation
- Principal Investigator
  
  GOTOH Tomomi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
Basic research for the ER stress-related diseasesPrincipal Investigator
- Principal Investigator
  
  ENDO Motoyoshi, 森正敬
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University

[Journal Article] Caspase-4 has a role in cell division in epithelial cells through actin depolymerization2024
- Author(s)
  Sumida K, Doi T, Obayashi K, Chiba Y, Nagasaka S, Ogino N, Miyagawa K, Baba R, Morimoto H, Hara H, Terabayashi T, Ishizaki T, Harada M, Endo M
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 695 Pages: 149394-149394
- DOI
  10.1016/j.bbrc.2023.149394
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18121, KAKENHI-PROJECT-22K08296, KAKENHI-PROJECT-22K08384, KAKENHI-PROJECT-23K07641, KAKENHI-PROJECT-21K07926, KAKENHI-PROJECT-21K07927, KAKENHI-PROJECT-21K07972, KAKENHI-PROJECT-21K08017, KAKENHI-PROJECT-18K15766, KAKENHI-PROJECT-23K27403
[Journal Article] ANGPTL8 links inflammation and poor differentiation, which are characteristics of malignant renal cell carcinoma2023
- Author(s)
  Takuo Matsukawa , Tomomitsu Doi , Kunie Obayashi , Kazuhiro Sumida , Naohiro Fujimoto , Motoyoshi Endo
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 4 Pages: 1410-1422
- DOI
  10.1111/cas.15700
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07972, KAKENHI-PROJECT-22K08296, KAKENHI-PROJECT-20K08530
[Journal Article] Plasma Angiopoietin-Like Protein 2 Levels and Mortality Risk Among Younger-Old Japanese People: A Population-Based Case?Cohort Study2022
- Author(s)
  Zhao Wenjing、Morinaga Jun、Ukawa Shigekazu、Endo Motoyoshi、Yamada Hiroya、Kawamura Takashi、Wakai Kenji、Tsushita Kazuyo、Ando Masahiko、Suzuki Koji、Oike Yuichi、Tamakoshi Akiko
- Journal Title
  
  The Journals of Gerontology: Series A
  
  Volume: - Issue: 6 Pages: 1150-1158
- DOI
  10.1093/gerona/glac017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K02392, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-20K08530
[Journal Article] Involvement of activator protein-1 family members in β-catenin and p300 association on the genome of PANC-1 cells2022
- Author(s)
  Doi Tomomitsu、Hojo Hironori、Ohba Shinsuke、Obayashi Kunie、Endo Motoyoshi、Ishizaki Toshimasa、Katoh Akira、Kouji Hiroyuki
- Journal Title
  
  Heliyon
  
  Volume: 8 Issue: 2 Pages: e08890-e08890
- DOI
  10.1016/j.heliyon.2022.e08890
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-21K07972, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-21K19611, KAKENHI-PROJECT-21K19883, KAKENHI-PROJECT-20K08530
[Journal Article] Angiopoietin-like protein 2 decreases peritoneal metastasis of ovarian cancer cells by suppressing anoikis resistance.2021
- Author(s)
  Takeshita Y, Motohara T, Kadomatsu T, Doi T, Obayashi K, Oike Y, Katabuchi H, Endo M.
- Journal Title
  
  Biochem Bioph Res Commun
  
  Volume: 561 Pages: 26-32
- DOI
  10.1016/j.bbrc.2021.05.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-19K09826, KAKENHI-PROJECT-20K08530, KAKENHI-PROJECT-20K09673, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-20K18223
[Journal Article] Tumor cell-derived angiopoietin-like protein 2 establishes a preference for glycolytic metabolism in lung cancer cells.2020
- Author(s)
  Osumi H, Horiguchi H, Kadomatsu T, Tashiro K, Morinaga J, Takahashi T, Ikeda K, Ito T, Suzuki M, Endo M, Oike Y
- Journal Title
  
  Cancer Sci
  
  Volume: - Issue: 4 Pages: 1241-1253
- DOI
  10.1111/cas.14337
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PROJECT-18K15246, KAKENHI-PROJECT-20K08530, KAKENHI-PROJECT-16H02468, KAKENHI-PROJECT-18H02809, KAKENHI-PROJECT-18K07236
[Journal Article] The Roles of ANGPTL Families in Cancer Progression2019
- Author(s)
  Endo M
- Journal Title
  
  Journal of UOEH
  
  Volume: 41 Issue: 3 Pages: 317-325
- DOI
  10.7888/juoeh.41.317
- NAID
  130007709766
- ISSN
  0387-821X, 2187-2864
- Year and Date
  2019-09-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08663
[Journal Article] Loss of Endogenous HMGB2 Promotes Cardiac Dysfunction and Pressure Overload-Induced Heart Failure in Mice2019
- Author(s)
  Sato M, Miyata K, Tian Z, Kadomatsu T, Ujihara Y, Morinaga J, Horiguchi H, Endo M, Zhao J, Zhu S, Sugizaki T, Igata K, Muramatsu M, Minami T, Ito T, Bianchi ME, Mohri S, Araki K, Node K, Oike Y
- Journal Title
  
  Circ J
  
  Volume: 83 Issue: 2 Pages: 368-378
- DOI
  10.1253/circj.CJ-18-0925
- NAID
  130007557092
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2019-01-25
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PROJECT-18K15246, KAKENHI-PUBLICLY-17H05652, KAKENHI-PROJECT-18H02809, KAKENHI-PROJECT-18H02904, KAKENHI-PROJECT-17H04740, KAKENHI-PROJECT-16K07093, KAKENHI-PROJECT-16K09504, KAKENHI-PROJECT-17K15622, KAKENHI-PROJECT-18KT0026, KAKENHI-PROJECT-19K17607, KAKENHI-PUBLICLY-19H04972, KAKENHI-PROJECT-17H03580, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18K19519
[Journal Article] keratinocytes increase melanogenesis via ANGPTL2 induction, an activity antagonized by Chrysanthemum extract.2019
- Author(s)
  Satou G, Maji D, Isamoto T, Oike Y, Endo M
- Journal Title
  
  Exp Dermatol
  
  Volume: 28 Issue: 2 Pages: 152-160
- DOI
  10.1111/exd.13862
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PUBLICLY-17H05652, KAKENHI-PROJECT-18H02809
[Journal Article] MiR-204-5p: a novel candidate urinary biomarker of Xp11.2 translocation renal cell carcinoma.2019
- Author(s)
  Kurahashi R, Kadomatsu T, Baba M, Hara C, Itoh H, Miyata K, Endo M, Morinaga J, Terada K, Araki K, Eto M, Schmidt LS, Kamba T, Linehan WM, Oike Y.
- Journal Title
  
  Cancer Science
  
  Volume: 印刷中 Issue: 6 Pages: 1897-1908
- DOI
  10.1111/cas.14026
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19619, KAKENHI-PROJECT-18H02938, KAKENHI-PROJECT-18K07236, KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-18H02809, KAKENHI-PROJECT-17K08663, KAKENHI-PROJECT-18K19519
[Journal Article] Association of circulating ANGPTL 3, 4, and 8 levels with medical status in a population undergoing routine medical checkups: A cross-sectional study.2018
- Author(s)
  Morinaga J, Zhao J, Endo M, Kadomatsu T, Miyata K, Sugizaki T, Okadome Y, Tian Z, Horiguchi H, Miyashita K, Maruyama N, Mukoyama M, Oike Y.
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 3 Pages: e0193731-e0193731
- DOI
  10.1371/journal.pone.0193731
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PROJECT-17K09706, KAKENHI-PROJECT-18K15246, KAKENHI-PROJECT-15K06836
[Journal Article] Circulating ANGPTL2 Levels Increase in Humans and Mice Exhibiting Cardiac Dysfunction2018
- Author(s)
  Tian Z, Miyata K, Morinaga J, Horiguchi H, Kadomatsu T, Endo M, Zhao J, Zhu S, Sugizaki T, Sato M, Terada K, Okumura T, Murohara T, Oike Y.
- Journal Title
  
  Circ J
  
  Volume: 82 Issue: 2 Pages: 437-447
- DOI
  10.1253/circj.CJ-17-0327
- NAID
  130006320284
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PROJECT-17F17121, KAKENHI-PROJECT-15K06836
[Journal Article] Angiopoietin-like protein 2 promotes chondrogenic differentiation during bone growth as a cartilage matrix factor.2018
- Author(s)
  Tanoue H, Morinaga J, Yoshizawa T, Yugami M, Itoh H, Nakamura T, Uehara Y, Masuda T, Odagiri H, Sugizaki T, Kadomatsu T, Miyata K, Endo M, Terada K, Ochi H, Takeda S, Yamagata K, Fukuda T, Mizuta H, Oike Y.
- Journal Title
  
  Osteoarthritis Cartilage
  
  Volume: 26 Issue: 1 Pages: 108-117
- DOI
  10.1016/j.joca.2017.10.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-15K06836
[Journal Article] Age-dependent increase in angiopoietin-like protein 2 accelerates skeletal muscle loss in mice.2018
- Author(s)
  Zhao J, Tian Z, Kadomatsu T, Xie P, Miyata K, Sugizaki T, Endo M, Zhu S, Fan H, Horiguchi H, Morinaga J, Terada K, Yoshizawa T, Yamagata K, Oike Y.
- Journal Title
  
  J Biol Chem
  
  Volume: 293 Issue: 5 Pages: 1596-1609
- DOI
  10.1074/jbc.m117.814996
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PUBLICLY-17H05652, KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-17F17121, KAKENHI-PROJECT-16K09504, KAKENHI-PROJECT-15K06836, KAKENHI-PROJECT-16K15445, KAKENHI-PROJECT-18K19519
[Journal Article] TET2-dependent IL-6 induction mediated by the tumor microenvironment promotes tumor metastasis in osteosarcoma.2018
- Author(s)
  Itoh H, Kadomatsu T, Tanoue H, Yugami M, Miyata K, Endo M, Morinaga J, Kobayashi E, Miyamoto T, Kurahashi R, Terada K, Mizuta H, Oike Y.
- Journal Title
  
  Oncogene
  
  Volume: 印刷中 Issue: 22 Pages: 2903-2920
- DOI
  10.1038/s41388-018-0160-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PUBLICLY-17H05652, KAKENHI-PROJECT-18H02930, KAKENHI-PROJECT-15K06836
[Journal Article] Treatment of diabetic mice with the SGLT2 inhibitor TA-1887 antagonizes diabetic cachexia and decreases mortality.2017
- Author(s)
  Sugizaki T, Zhu S, Guo G, Matsumoto A, Zhao J, Endo M, Horiguchi H, Morinaga J, Tian Z, Kadomatsu T, Miyata K, Itoh H, Oike Y
- Journal Title
  
  NPJ Aging Mech Dis
  
  Volume: 3 Issue: 1 Pages: 12-12
- DOI
  10.1038/s41514-017-0012-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PROJECT-15K06836
[Journal Article] ANGPTL2　― A New Causal Player in Accelerating Heart Disease Development in the Aging ―2017
- Author(s)
  Oike Y, Tian Z, Miyata K, Morinaga J, Endo M, Kadomatsu T.
- Journal Title
  
  Circ J
  
  Volume: 81 Issue: 10 Pages: 1379-1385
- DOI
  10.1253/circj.CJ-17-0854
- NAID
  130006099927
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PUBLICLY-17H05652, KAKENHI-PROJECT-15K06836, KAKENHI-PROJECT-16K15445
[Journal Article] ANGPTL2 expression in intestinal stem cell niche controls epithelial regeneration and homeostasis.2017
- Author(s)
  Horiguchi H, Endo M, Kawane K, Kadomatsu T, Terada K, Morinaga J, Araki K, Miyata K, Oike Y,
- Journal Title
  
  EMBO Journal
  
  Volume: 36 Issue: 4 Pages: 409-424
- DOI
  10.15252/embj.201695690
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01520, KAKENHI-PROJECT-15H06508, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26713011, KAKENHI-PROJECT-16K07093, KAKENHI-PROJECT-15K06836
[Journal Article] Angiopoietin-like protein 2 increases renal fibrosis by accelerating transforming growth factor-β signaling in chronic kidney disease.2016
- Author(s)
  Jun Morinaga, Tsuyoshi Kadomatsu, Keishi Miyata, Motoyoshi Endo, Kazutoyo Terada, Zhe Tian, Taichi Sugizaki, Hiroki Tanigawa, Jiabin Zhao, Shunshun Zhu, Michio Sato, Kimi Araki, Ken-ichi Iyama, Kengo Tomita, Masashi Mukoyama, Kimio Tomita, Kenichiro Kitamura, Yuichi Oike
- Journal Title
  
  Kidney International
  
  Volume: 89 Issue: 2 Pages: 327-341
- DOI
  10.1016/j.kint.2015.12.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06836, KAKENHI-PROJECT-15K09031, KAKENHI-PROJECT-26461226, KAKENHI-PUBLICLY-15H01520, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-26860639, KAKENHI-PROJECT-26861112, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-26670405
[Journal Article] Angiopoietin-like protein 2 is a multistep regulator of inflammatory neovascularization in a murine model of age-related macular degeneration.2016
- Author(s)
  M. Hirasawa, K. Takubo, H. Osada, S. Miyake, E. Toda, M. Endo, K. Umezawa, K. Tsubota, Y. Oike and Y. Ozawa
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 291 Issue: 14 Pages: 7373-7385
- DOI
  10.1074/jbc.m115.710186
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350975, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-25462734, KAKENHI-PUBLICLY-15H01520, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-15K10903, KAKENHI-PROJECT-26670405
[Journal Article] Macrophage-derived angiopoietin-like protein 2 exacerbates brain damage by accelerating acute inflammation after ischemia-reperfusion.2016
- Author(s)
  Amadatsu T, Morinaga J, Kawano T, Terada K, Kadomatsu T, Miyata K, Endo M, Kasamo D, Kuratsu JI & Oike Y
- Journal Title
  
  PLOS ONE
  
  Volume: 11 Issue: 11 Pages: e0166285-e0166285
- DOI
  10.1371/journal.pone.0166285
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-15K06836
[Journal Article] ANGPTL2 activity in cardiac pathologies accelerates heart failure by perturbing cardiac function and energy metabolism.2016
- Author(s)
  Tian Z, Miyata K, Kadomatsu T, Horiguchi H, Fukushima H, Tohyama S, Ujihara Y, Okumura T, Yamaguchi S, Zhao J, Endo M, Morinaga J, Sato M, Sugizaki T, Zhu S, Terada K, Sakaguchi H, Komohara Y, Takeya M, Takeda N, Araki K, Manabe I, Fukuda K, Otsu K, Wada J, Murohara T, Mohri S, Yamashita JK, Sano M, Oike Y.
- Journal Title
  
  Nature Communications
  
  Volume: 7 Issue: 1 Pages: 13016-13016
- DOI
  10.1038/ncomms13016
- NAID
  120006345014
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01520, KAKENHI-PROJECT-15H06508, KAKENHI-PROJECT-26282127, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26293218, KAKENHI-PROJECT-16K09504, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-15K06836, KAKENHI-PROJECT-16K15445
[Journal Article] ANGPTL2 increases bone metastasis of breast cancer cells through enhancing CXCR4 signaling.2015
- Author(s)
  Masuda T, Endo M, Yamamoto Y, Odagiri H, Kadomatsu T, Nakamura T, Tanoue H, Ito H, Yugami M, Miyata K, Morinaga J, Horiguchi H, Motokawa I, Terada K, Morioka MS, Manabe I, Iwase H, Mizuta H, Oike Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 9170-9170
- DOI
  10.1038/srep09170
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-25870543, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26670405
[Journal Article] The exacerbating roles of CCAAT/enhancer-binding protein homologous protein (CHOP) in the development of bleomycin-induced pulmonary fibrosis and the preventive effects of tauroursodeoxycholic acid (TUDCA) against pulmonary fibrosis in mice.2015
- Author(s)
  Tanaka Y, Ishitsuka Y, Hayasaka M, Yamada Y, Miyata K, Endo M, Kondo Y, Moriuchi H, Irikura M, Tanaka K, Mizushima T, Oike Y, Irie T.
- Journal Title
  
  Pharmacol Res.
  
  Volume: 99 Pages: 52-62
- DOI
  10.1016/j.phrs.2015.05.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460104, KAKENHI-PUBLICLY-15H01520, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-26670405
[Journal Article] The role of ANGPTL2-induced chronic inflammation in lifestyle diseases and cancer2015
- Author(s)
  Yuichi Oike, Tsuyoshi Kadomatsu, Motoyoshi Endo
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 35 Issue: 4 Pages: 193-202
- DOI
  10.2492/inflammregen.35.193
- NAID
  130005103502
- ISSN
  1880-8190, 1880-9693
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06836, KAKENHI-PUBLICLY-15H01159
[Journal Article] Angiopoietin-like protein 2 accelerates carcinogenesis by activating chronic inflammation and oxidative stress2014
- Author(s)
  Aoi J, Endo M, Kadomatsu T, Miyata K, Ogata A, Horiguchi H, Odagiri H, Masuda T, Fukushima S, Jinnin M, Hirakawa S, Sawa T, Akaike T, Ihn H and Oike Y
- Journal Title
  
  Mol. Cancer Res
  
  Volume: 12 Issue: 2 Pages: 239-249
- DOI
  10.1158/1541-7786.mcr-13-0336
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25253020, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-25870545, KAKENHI-PROJECT-25870554
[Journal Article] Angiopoietin-like protein 2 induced by mechanical stress accelerates degeneration and hypertrophy of the ligamentum flavum in lumbar spinal canal stenosis.2014
- Author(s)
  Nakamura T, Okada T, Endo M, Kadomatsu T, Taniwaki T, Sei A, Odagiri H, Masuda T, Fujimoto T, Nakamura T, Oike Y, Mizuta H.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 1 Pages: e85542-e85542
- DOI
  10.1371/journal.pone.0085542
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461192
[Journal Article] The secreted protein ANGPTL2 promotes metastasis of osteosarcoma cells through integrin alpha5beta1, p38 MAPK, and matrix metalloproteinases.2014
- Author(s)
  Odagiri et al.
- Journal Title
  
  Science Signaling
  
  Volume: 7 Issue: 309
- DOI
  10.1126/scisignal.2004612
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22113009, KAKENHI-PROJECT-24370084, KAKENHI-PROJECT-25293050, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-25870543, KAKENHI-PROJECT-25870554, KAKENHI-PROJECT-26670107
[Journal Article] Diverse roles of ANGPTL2 in physiology and pathophysiology.2014
- Author(s)
  Kadomatsu T, Endo M, Miyata K, Oike Y.
- Journal Title
  
  Trends Endocrinol Metab.
  
  Volume: 25(5) Issue: 5 Pages: 245-54
- DOI
  10.1016/j.tem.2014.03.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-25870543, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26670405
[Journal Article] Serum ANGPTL2 levels reflect clinical features of breast cancer patients: implications for the pathogenesis of breast cancer metastasis.2014
- Author(s)
  Endo M, Yamamoto Y, Nakano M, Masuda T, Odagiri H, Horiguchi H, Miyata K, Kadomatsu T, Motokawa I, Okada S, Iwase H, Oike Y.
- Journal Title
  
  The International Journal of Biological Markers
  
  Volume: 印刷中 Issue: 3 Pages: 0-0
- DOI
  10.5301/jbm.5000080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24791383, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461192, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26670405
[Journal Article] Angiopoietin-like protein 2 renders colorectal cancer cells resistant to chemotherapy by activating spleen tyrosine kinase-phosphoinositide 3-kinase-dependent anti-apoptotic signaling.2014
- Author(s)
  Horiguchi H, Endo M, Miyamoto Y, Sakamoto Y, Odagiri H, Masuda T, Kadomatsu T, Tanoue H, Motokawa I, Terada K, Morioka MS, Manabe I, Baba H, Oike Y.
- Journal Title
  
  Cancer Science
  
  Volume: 105 Issue: 12 Pages: 1550-1559
- DOI
  10.1111/cas.12554
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-25870543, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26462020, KAKENHI-PROJECT-26670405, KAKENHI-PROJECT-26861050
[Journal Article] Role of endothelial cell-derived angptl2 in vascular inflammation leading to endothelial dysfunction and atherosclerosis progression.2014
- Author(s)
  Horio E, Kadomatsu T, Miyata K, Arai Y, Hosokawa K, Doi Y, et al.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 34 Issue: 4 Pages: 790-800
- DOI
  10.1161/atvbaha.113.303116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23617024, KAKENHI-PROJECT-24590797, KAKENHI-PROJECT-24590898, KAKENHI-PROJECT-24689041, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-25670453, KAKENHI-PROJECT-25870543, KAKENHI-PROJECT-25870553, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26290035, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26640069, KAKENHI-PROJECT-26670405
[Journal Article] Macrophage-derived Angiopoietin- like Protein 2 Accelerates the Development of Abdominal Aortic Aneurysm.2012
- Author(s)
  Tazume H, Miyata K, Tian Z, Endo M, Horiguchi H, Takahashi O, Horio E, Tsukano H, Kadomatsu T, Nakashima Y, Kunitomo R, Kaneko Y, Moriyama S, Sakaguchi H, Okamoto K, Hara M, Yoshinaga T, Yoshimura K, Aoki H, Araki K, Hao H, Kawasuji M, Oike Y.
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 32(6) Issue: 6 Pages: 1400-1409
- DOI
  10.1161/atvbaha.112.247866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659232, KAKENHI-PROJECT-23310135, KAKENHI-PROJECT-24390334, KAKENHI-PUBLICLY-23112516, KAKENHI-PUBLICLY-24115712
[Journal Article] The roles of angiopoietin-like protein ANGPTL2 in inflammatory carcinogenesis and tumor metastasis2012
- Author(s)
  Endo M, Kadomatsu T, and Oike Y
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 32 Pages: 158-164
- NAID
  130004943822
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23112516
[Journal Article] C/EBP homologous protein deficiency attenuates myocardial reperfusion injury by inhibiting myocardial apoptosis and inflammation2011
- Author(s)
  Yuji Miyazaki
- Journal Title
  
  Arterioscler.Thromb.Vasc.Biol.
  
  Volume: 31 Issue: 5 Pages: 1124-1132
- DOI
  10.1161/atvbaha.111.224519
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22113524, KAKENHI-PROJECT-22790713, KAKENHI-PROJECT-23590365
[Journal Article] Endoplasmic reticulum stress-related inflammation and cardiovascular diseases.2011
- Author(s)
  T. Gotoh, M. Endo & Y. Oike.
- Journal Title
  
  Int. J. Inflam.,
  
  Volume: 2011 Pages: 1-8
- DOI
  10.4061/2011/259462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590365
[Journal Article] C/EBP Homologous Protein Deficiency Attenuates Myocardial Reperfusion Injury by Inhibiting Myocardial Apoptosis and Inflammation.2010
- Author(s)
  Miyazaki Y, Kaikita K, Endo M, Horio E, Miura M, Tsujita K, Hokimoto S, Yamamuro M, Iwawaki T, Gotoh T, Ogawa H, Oike Y.
- Journal Title
  
  Arterioscler Thromb.Vasc.Biol. 31
  
  Pages: 1124-1132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790775
[Journal Article] (*corresponding author) Molecular mechanisms of the LPS-induced non-apoptotic ER stress-CHOP pathway.2010
- Author(s)
  Y.Nakayama, M.Endo, H.Tsukano, M.Mori, Y.Oike, T.Gotoh.
- Journal Title
  
  J.Biochem. 147
  
  Pages: 471-483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590310
[Journal Article] (*corresponding author) The Endoplasmic Reticulum Stress-CHOP Pathway-mediated Apoptosis in Macrophages Contributes to the Instability of Atherosclerotic Plaques.2010
- Author(s)
  H.Tsukano, T.Gotoh, M.Endo, K.Miyata, H.Tazume, T.Kadomatsu, M.Yano, T.Iwawaki, K.Kohno, K.Araki, H.Mizuta, Y.Oike.
- Journal Title
  
  Arterioscler.Thromb.Vasc.Biol. 30
  
  Pages: 1925-1932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590310
[Journal Article] Molecular Mechanisms of the LPS-induced Non-apoptotic ER Stress-CHOP Pathway.2010
- Author(s)
  Nakayama Y, Endo M, Tsukano H, Mori M, Oike Y, Gotoh T.
- Journal Title
  
  J.Biochem. 147
  
  Pages: 471-483
- NAID
  10027874883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790775
[Journal Article] Molecular mechanisms of the LPS-induced non-apoptotic ER stress-CHOP pathway.2010
- Author(s)
  Nakayama Y, Endo M, et. al.
- Journal Title
  
  J.Biochem. 147
  
  Pages: 471-483
- NAID
  10027874883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790775
[Journal Article] The endoplasmic reticulum stress-C/EBP homologous protein pathway-mediated apoptosis in macrophages contributes to the instability of atherosclerotic plaques.2010
- Author(s)
  Tsukano H, Gotoh T, Endo M, Miyata K, Tazume H, Kadomatsu T, Yano M, Iwawaki T, Kohno K, Araki K, Mizuta H, Oike Y.
- Journal Title
  
  Arterioscler Thromb.Vasc.Biol. 30
  
  Pages: 1925-1932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790775
[Journal Article] Synoviocyte-derived angiopoietin-like protein 2 contributes to synovial chronic inflammation in rheumatoid arthritis.2010
- Author(s)
  Okada T, Tsukano H, Endo M, Tabata M, Miyata K, Kadomatsu T, Miyashita K, Semba K, Nakamura E, Tsukano M, Mizuta H, Oike Y.
- Journal Title
  
  Am.J.Pathol. 176
  
  Pages: 2309-2319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790775
[Journal Article] Angiopoietins contribute to lung development by regulating pulmonary vascular network formation.2009
- Author(s)
  Hato T, Kimura Y, Morisada T, Koh GY, Miyata K, Tabata M, Kadomatsu T, Endo M, Urano T, Arai F, Araki K, Suda T, Kobayashi K, Oike Y.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 381
  
  Pages: 218-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790775
[Journal Article] Angiopoietins contribute to lung development by regulating pulmonary vascular network formation2009
- Author(s)
  Hato T, Kimura Y, Morisada T, Koh GY, Miyata K, Tabata M, Kadomatsu T, Endo M, Urano T, Arai F, Araki K, Suda T, Kobayashi K, Oike Y
- Journal Title
  
  Biochem. Biophys. Res. Commun. 381(2)
  
  Pages: 218-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790563
[Journal Article] Positive role of CHOP, a transcription factor involved in the ER stress response in the development of colitis.2009
- Author(s)
  T.Namba, K.Tanaka, Y., Ito, T.Ishihara, T.Hoshino, T.Gotoh, M.Endo, K.Sato, T.Mizushima.
- Journal Title
  
  Am.J.Pathol. 174
  
  Pages: 1786-1798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590310
[Journal Article] Positive role of CCAAT/enhancer-binding protein homologous protein, a transcription factor involved in the endoplasmic reticulum stress response in the development of colitis.2009
- Author(s)
  Namba T, Tanaka K, Ito Y, Ishihara T, Hoshino T, Gotoh T, Endo M, Sato K, Mizushima T.
- Journal Title
  
  Am.J.Pathol. 174
  
  Pages: 1786-1798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790775
[Journal Article] Humanized anti-interleukin-6 receptor antibody suppresses tumor angiogenesis and in vivo growth of human oral squamous cell carcinoma.2009
- Author(s)
  Shinriki S, Jono H, Ota K, Ueda M, Kudo M, Ota T, Oike Y, Endo M, Ibusuki M, Hiraki A, Nakayama H, Yoshitake Y, Shinohara M, Ando Y.
- Journal Title
  
  Clin.Cancer Res. 15
  
  Pages: 5426-5434
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790775
[Journal Article] Endoplasmic Reticulum Stress-induced Transcriptional Factor CHOP and Cardiovascular Diseases.2009
- Author(s)
  Tomomi Gotoh, Motoyoshi Endo, Yuichi Oike
- Journal Title
  
  Current Hypertension Reviews 6
  
  Pages: 55-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790775
[Journal Article] Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance.2009
- Author(s)
  Tabata M, Kadomatsu T, Fukuhara S, Miyata K, Ito Y, Endo M, Urano T, Zhu HJ, Tsukano H, Tazume H, Kaikita K, Miyashita K, Iwawaki T, Shimabukuro M, Sakaguchi K, Ito T, Nakagata N, Yamada T, Katagiri H, Kasuga M, Ando Y, Ogawa H, Mochizuki N, Itoh H, Suda T, Oike Y.
- Journal Title
  
  Cell Metab. 10
  
  Pages: 178-188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790775
[Journal Article] Positive role of CCAAT/enhancer-binding protein homologous protein, a transcription factor involved in the endoplasmic reticulum stress response in thedevelopment of colitis.2009
- Author(s)
  Namba T, Tanaka K, Ito Y, Ishihara T, Hoshino T, Gotoh T, Endo M, Sato K, Mizushima T
- Journal Title
  
  Am. J. Pathol. 174(5)
  
  Pages: 1786-1798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790563
[Journal Article] C/EBP homologous protein is crucial for the acceleration of experimental pancreatitis2008
- Author(s)
  Suyama K, Ohmuraya M, Hirota M, Ozaki N, Ida S, Endo M, Araki K, Gotoh T, Baba H, Yamamura K
- Journal Title
  
  Biochem. Biophys. Res. Commun. 367(1)
  
  Pages: 176-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790563
[Journal Article] C/EBP Homologous Protein Is Crucial for the Acceleration of Experimental Pancreatitis.2008
- Author(s)
  K.Suyama, M.Ohmuraya, M.Hirota, N.Ozaki, S.Ida, M.Endo, K.Araki, T.Gotoh, H.Baba, K.Yamamura.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 367
  
  Pages: 176-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590310
[Journal Article] CHOP is crucial for the induction of caspase-11 and the pathogenesis of LPS-induced inflammation.2006
- Author(s)
  Endo, M., et al.
- Journal Title
  
  J.Immunol. 176
  
  Pages: 6245-6253
- Data Source
  KAKENHI-PROJECT-18590301
[Journal Article] CHOP is crucial for the induction of caspase-11 and the pathogenesis of LPS-induced inflammation2006
- Author(s)
  Endo, M., et. al.
- Journal Title
  
  J.Immunol. 176
  
  Pages: 6245-6253
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590301
[Journal Article] CHOP is crucial for the induction of caspase-11 and the pathogenesis of LPS-induced inflammation.2006
- Author(s)
  M.Endo, S.Akira, M.Mori, T.Gotoh*.
- Journal Title
  
  J. Immunol. 176
  
  Pages: 6245-6253
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390096
[Journal Article] CHOP is crucial for the induction of caspase-11 and the pathogenesis of LPS-induced inflammation.2006
- Author(s)
  M., Endo, S., Akira, M., Mori, T., Gotoh*
- Journal Title
  
  J. Immunol 176
  
  Pages: 6245-6253
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590301
[Journal Article] CHOP is crucial for the induction of caspase-11 and the pathogenesis of LPS-induced inflammation.2006
- Author(s)
  Endo, M., et al.
- Journal Title
  
  J.Immunol. 176
  
  Pages: 6245-6253
- Data Source
  KAKENHI-PROJECT-17390096
[Journal Article] CHOP is crucial for the induction of caspase-11 and the pathogenesis of LPS-induced inflammation.2006
- Author(s)
  Endo, M., et al.
- Journal Title
  
  J. Immunol. 176
  
  Pages: 6245-6253
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390096
[Journal Article] The endoplasmic reticulum stress pathway involving CHOP is activated in the lung of the septic shock model mouse.2005
- Author(s)
  M.Endo, S.Oyadomari, M.Suga, M.Mori, T.Gotoh.
- Journal Title
  
  J. Biocem. 138
  
  Pages: 501-507
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390096
[Journal Article] The endoplasmic reticulum stress pathway involving CHOP is activated in the lung of the septic shock model mouse.2005
- Author(s)
  Endo, M., et al.
- Journal Title
  
  Journal of Biochemistry 138
  
  Pages: 501-507
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390096
[Presentation] Caspase4 regulates polyploidization of hepatocellular carcinoma cells through cofilin activity2023
- Author(s)
  隅田和広、土井知光、大林邦衣、松川卓生、千葉要佑、長坂昌平、小山倫太郎、遠藤元誉
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K07641
[Presentation] 腫瘍細胞におけるCaspase-4発現誘導機構の解析2023
- Author(s)
  大林邦衣、土井知光、千葉要佑、隅田和広、長坂昌平、遠藤元誉
- Organizer
  第46回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-23K07641
[Presentation] CASP4 in epithelial cells regulates cell division and cell size through actin depolymerization2023
- Author(s)
  隅田和広、土井知光、大林邦衣、松川卓生、千葉要佑、長坂昌平、小山倫太郎、遠藤元誉
- Organizer
  第46回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-23K07641
[Presentation] 非小細胞肺癌においてCaspase-4はNF-kB経路を介して血管新生を促進する2023
- Author(s)
  千葉要祐、遠藤元誉、土井知光、大林邦衣、矢寺和博
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-23K07641
[Presentation] Angiopoietin-like protein-8(ANGPTL8)は、淡明細胞型腎癌の分化に関与する2022
- Author(s)
  松川卓生、土井知光、大林邦衣、遠藤元誉
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20K08530
[Presentation] 肝細胞におけるCaspase4のストレス調整因子としての機能解析2022
- Author(s)
  隅田和広, 長坂昌平, 千葉要祐, 松川卓生, 大林邦衣, 土井知光, 遠藤元誉
- Organizer
  第16回日本臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-20K08530
[Presentation] Angiopoietin-like protein 8(ANGPTL8)は淡明細胞型腎癌の未分化状態の維持と腫瘍微小環境形成に関わる2022
- Author(s)
  松川卓生、土井知光、大林邦衣、藤本直浩、遠藤元誉
- Organizer
  第32回泌尿器科分子・細胞研究会
- Data Source
  KAKENHI-PROJECT-20K08530
[Presentation] Angptl2によって惹起される炎症による発がん制御メカニズム解明2013
- Author(s)
  遠藤元誉、小田切陽樹、舛田哲朗、堀口晴紀、中野正啓、尾池雄一
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25461192
[Presentation] 新規炎症関連因子ANGPTL2による肺がんの浸潤・転移分子機構2013
- Author(s)
  遠藤元誉、本川郁代、羽藤泰
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25461192
[Presentation] がん浸潤・転移におけるアンジオポエチン様因子2の役割2012
- Author(s)
  遠藤元誉
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（北海道札幌市）
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PUBLICLY-23112516
[Presentation] Role of Angiopoietin-like protein 2 in carcinogenesis and metastasis2012
- Author(s)
  遠藤元誉（尾池雄一）
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（北海道札幌市）
- Year and Date
  2012-09-19
- Invited
- Data Source
  KAKENHI-PUBLICLY-23112516
[Presentation] がん進展・転移におけるAngpt12の役割2011
- Author(s)
  遠藤元誉
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)(招待講演)
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PUBLICLY-23112516
[Presentation] 肺癌の浸潤・転移におけるアンジオポエチン様因子2の機能解析2010
- Author(s)
  遠藤元誉
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21790775
[Presentation] 肺癌の浸潤・転移におけるアンジオポエチン様因子2の機能解析2010
- Author(s)
  遠藤元誉
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21790775
[Presentation] 一般演題:「動脈硬化病態における小胞体ストレス-CHOP経路の関与」2010
- Author(s)
  後藤知己、束野寛人、宮田敬士、田爪宏和、矢野正人、遠藤元誉、尾池雄一
- Organizer
  第19回日本Cell Death学会学術集会
- Place of Presentation
  名古屋市愛知県産業労働センター
- Year and Date
  2010-08-01
- Data Source
  KAKENHI-PROJECT-20590310
[Presentation] 一般演題:「小胞体ストレス-CHOP経路のアポトーシス誘導と非誘導経路の解析」2009
- Author(s)
  後藤知己、遠藤元誉、中山陽一郎、束野寛人、森正敬、尾池雄一
- Organizer
  第18回日本アポトーシス研究会学術集会
- Place of Presentation
  長崎市長崎大学坂本キャンパス
- Year and Date
  2009-08-01
- Data Source
  KAKENHI-PROJECT-20590310
[Presentation] 一般演題:「動脈硬化病態における小胞体ストレス-CHOP経路の関与」2009
- Author(s)
  後藤知己、束野寛人、宮田敬士、田爪宏和、矢野正人、遠藤元誉、尾池雄一
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸市神戸国際展示場
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20590310
[Presentation] 小胞体ストレス時に誘導されるshort form caspase-11の意義解明2008
- Author(s)
  遠藤元誉、中山陽一郎、森正敬、尾池雄一、後藤知己
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19790563
[Presentation] 一般演題:「小胞体ストレス-CHOP経路のアポトーシス誘導と炎症誘導の二面性の分子機序」2008
- Author(s)
  後藤知己、中山陽一郎、遠藤元誉、森正敬、尾池雄一
- Organizer
  第17回日本アポトーシス研究会学術集会
- Place of Presentation
  京都市メルパルク京都
- Year and Date
  2008-08-01
- Data Source
  KAKENHI-PROJECT-20590310
[Presentation] 一般演題:「炎症病態における小胞体ストレス-CHOP経路の特異性」2008
- Author(s)
  後藤知己、中山陽一郎、遠藤元誉、束野寛人、森正敬、尾池雄一
- Organizer
  第81回日本生化学会大会・第31回日本分子生物学会年会合同年会
- Place of Presentation
  神戸市神戸国際会議場
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20590310
[Presentation] 一般演題:「小胞体ストレス-CHOP経路を介するLPS誘導性炎症病態の解析」2008
- Author(s)
  後藤知己、中山陽一郎、遠藤元誉、森正敬、尾池雄一
- Organizer
  第8回日本NO学会学術集会
- Place of Presentation
  仙台市仙台国際センター
- Year and Date
  2008-05-10
- Data Source
  KAKENHI-PROJECT-20590310
[Presentation] 小胞体ストレス時に誘導されるcaspase-11 short formの意義2008
- Author(s)
  遠藤元誉
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19790563
[Presentation] 炎症時に誘導される小胞体ストレス経路の特徴と意義2007
- Author(s)
  中山陽一郎、遠藤元誉、宮田敬士、尾池雄一、後藤知己
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19790563
[]

1. GOTOH Tomomi (20264286)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. OIKE Yuichi (90312321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. INOUE Hiromasa (30264039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Kadomatsu Tsuyoshi (90555757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. BABA Masaya (10347304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 森正敬 (40009650)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. TANAKA Kenichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. OHBA Shinsuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. HARA Hideki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. DOI Tomomitsu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. ARAI Yasumichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 宮田敬士

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 青木浩樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 吉村耕一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 澤智裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 赤池孝章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 後藤知巳

# of Collaborated Projects: 0 results

# of Collaborated Products: 14 results
18. 鵜川重和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 玉腰暁子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 若井健志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 北條宏徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 梅沢一夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 中野正啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ENDO Motoyoshi 遠藤 元誉

Research Projects

Research Products

Co-Researchers

Elucidation of the function of inflammatory caspases in lung cancer progressionPrincipal Investigator

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Development of novel lung injury therapies based on the regulation of lung tissue stem cellsPrincipal Investigator

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The research for developing a method for controlling cancer invasion and metastasis by elucidating the mechanism of cancer metabolic changePrincipal Investigator

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Elucidation of molecular mechanisms underlying development and progression of rare cancers caused by alteration of transcriptional regulation

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The role of Angptl2 expression in lung for interstitial pneumoniaPrincipal Investigator

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新規炎症関連因子ＡＮＧＰＴＬ２による癌の発症・浸潤・転移の分子機構解明Principal Investigator

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Involvement of ER stress pathway in chronic inflammatory diseases.

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Functional analysis of the ER stress response in the development of lung cancer metastasisPrincipal Investigator

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Analysis of the pathological roles of ER stress-induced transcriptional factors

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The study of ER stress pathway and inflammationPrincipal Investigator

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Pathological roles of ER stress pathway in inflammation

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Basic research for the ER stress-related diseasesPrincipal Investigator

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[Journal Article] Caspase-4 has a role in cell division in epithelial cells through actin depolymerization2024

Author(s)

Journal Title

DOI

ENDO Motoyoshi 遠藤元誉