UCHINAMI Hiroshi 打波宇

Researcher Number	40400486
Other IDs
Affiliation (based on the past Project Information) *help	2020 – 2022: 秋田大学, 医学系研究科, 准教授 2012 – 2013: 秋田大学, 医学(系)研究科(研究院), 准教授 2010 – 2011: 秋田大学, 医学部, 講師 2010: 秋田大学, 大学院・医学研究科消化器外科, 助教 2009 – 2010: 秋田大学, 大学院・医学系研究科, 助教 2007 – 2008: Akita University, School of medicine, Assistant Professor 2006: 秋田大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Digestive surgery Except Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related / Medical systems
Keywords	Principal Investigator Stress Response / Liver Sureer / ストレス応答 / 肝臓外科学 / 外科治療 / 肝切除 / リンパ節郭清 / リンパ節転移 / 肝内胆管癌 Except Principal Investigator 肝切除 … More / JAK/STAT経路 / Reg遺伝子 / 肝再生促進 / sphingosine kinase-1 / STAT3 / Reg3遺伝子 / ALPPS / 門脈結紮 / Muse細胞 / 門脈塞栓 / JAK2/STAT3経路 / Reg3 / ALPPS手術 / 肝再生 / 肝切徐術 / 薬物動態の個体内変動 / 薬剤忍容性 / 周術期薬理学 / 個別化治療 / 肝切除術 / 代謝 / 有害事象 / 認容性 / 手術侵襲 / 薬物代謝動態 / ゲムシタビン / 補助化学療法 / 胆道癌 / 胆道外科学 / 肝虚血再還流障害 / 肝虚血再灌流障害 / 強力超音波 / 環境制御 / 酸化ストレス / 熱ショックタンパク質 / ストレス応答 / 臓器保護 / 音響化学 / 超音波 / ストレス / 蛋白質 / 外科 Less

Elucidation of Reg expression control mechanism as a novel regulatory factor of liver regeneration
- Principal Investigator
  
  Yamamoto Yuzo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Akita University
An analysis of intrahepatic lymphatic invasion in the patient with intrahepatic cholangiocarcinomaPrincipal Investigator
- Principal Investigator
  
  UCHINAMI Hiroshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Akita University
Stress tolerance of the cell induced by a sonochemical preconditioning using ultrasound
- Principal Investigator
  
  KUME Makoto
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical systems
- Research Institution
  Akita University
Effect of liver resection on the pharmacodynamics of gemcitabine hydrohloride
- Principal Investigator
  
  YAMAMOTO Yuzo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Akita University
ERストレスと蛋白合成品質管理からみた術後肝再生に関する研究
- Principal Investigator
  
  YAMAMOTO Yuzo
- Project Period (FY)
  2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Akita University
Modulation of intracellular signal pathway for preventing liver damage after extended hepatectomyPrincipal Investigator
- Principal Investigator
  
  UCHINAMI Hiroshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Akita University

All 2022 2021 2020 2014 2013 2012 2010 2009 2007 2006

All Journal Article Presentation

[Journal Article] 99mTc-GSA scintigraphy for assessing the functional volume ratio of the future liver remnant in the routine practice of liver resection.2022
- Author(s)
  Iida M, Yamamoto Y, Katoh H, Taniguchi N, Abe Y, Kumagai K, Uchinami H.
- Journal Title
  
  Surgery Open Science
  
  Volume: 8 Pages: 1-8
- DOI
  10.1016/j.sopen.2021.12.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09072
[Journal Article] Reg3 and Reg3 expressions followed by JAK2/STAT3 activation play a pivotal role in the acceleration of liver hypertrophy in a rat ALPPS Model.2020
- Author(s)
  Otsuka N, Yoshioka M, Abe Y, Nakagawa Y, Uchinami H, Yamamoto Y.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 21 Issue: 11 Pages: 4077-4077
- DOI
  10.3390/ijms21114077
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09072
[Journal Article] Nrf2 activation protects the liver from ischemia-reperfusion injury in mice2014
- Author(s)
  Kudoh K, Uchinami H, Seki E, Yamamoto Y
- Journal Title
  
  Annals of Surgery
  
  Volume: 印刷中 Issue: 1 Pages: 118-127
- DOI
  10.1097/sla.0000000000000287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591979
[Journal Article] Prognosis analysis of sarcomatous intrahepatic cholangiocarcinoma from a view of the literature2014
- Author(s)
  Watanabe G, Uchinami H, Yoshioka M, Nanjo H, Yamamoto Y
- Journal Title
  
  International journal of clinical oncology
  
  Volume: 印刷中 Issue: 3 Pages: 490-496
- DOI
  10.1007/s10147-013-0586-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591979
[Journal Article] Nrf2 activation protects the liver from ischemia/reperfusion injury in mice2014
- Author(s)
  Kudoh K, Uchinami H, Yoshioka M, Seki E, Yamamoto Y.
- Journal Title
  
  Ann Surg
  
  Volume: 260(1) Pages: 118-127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591979
[Journal Article] Diffusion-weighted MRI for differential diagnosis in gallbladder lesions with special reference to ADC cut-off value2013
- Author(s)
  Yoshioka M, Watanabe G, Uchinami H, Miyazawa H, Abe Y, Ishiyama K, Hashimoto M, Nakamura A, Yamamoto Y
- Journal Title
  
  Hepatogastroenterology
  
  Volume: 60(124) Pages: 692-698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591979
[Journal Article] Diffusion-Weighted MRI for differential diagnosis in gallbladder lesions with special reference to ADC cut-off value2013
- Author(s)
  Yoshioka M, Watanabe G, Uchinami H, Miyazawa H, Abe Y, Ishiyama K, Hashimoto M, Nakamura A, Yamamoto Y.
- Journal Title
  
  Hepatogastroenterology
  
  Volume: 60(124) Pages: 692-698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591979
[Journal Article] Transfection of naked nuclear factor-kB decoy oligodeoxynucleotides into liver by rapid portal vein infusion in rats : its effect on ischemia-reperfusion injury of liver2012
- Author(s)
  Watanabe G, Uchinami H, Yoshioka M, Abe Y, Kikuchi I, Iwasaki W, Kume M, Yamamoto Y.
- Journal Title
  
  Hum Gene Ther
  
  Volume: 23(4) Pages: 428-436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591979
[Journal Article] Liver epithelial cells proliferate under hypoxia and protect the liver from ischemic injury via expression of HIF-1 alpha target genes2012
- Author(s)
  Yuki Abe, Hiroshi Uchinami et al
- Journal Title
  
  Surgery
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591979
[Journal Article] Enhancement of liver regeneration by adenosine triphosphate-sensitive K-channel opener (diazoxide) after partial hepatectomy2012
- Author(s)
  Nakagawa Y, Yoshioka M, Abe Y, Uchinami H, Ohba T, Ono K, Yamamoto Y.
- Journal Title
  
  Transplantation
  
  Volume: 93(11) Pages: 1094-1100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591979
[Journal Article] Liver epithelial cells proliferate under hypoxia and protect the liver from ischemic injury via expression of HIF-1 alpha target genes2012
- Author(s)
  Abe Y, Uchinami H, Kudoh K, Nakagawa Y, Ise N, Watanabe G, Sato T, Seki E, Yamamoto Y.
- Journal Title
  
  Surgery
  
  Volume: 152(5) Pages: 869-878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591979
[Journal Article] 急速な転帰をたどった下部胆管原発の未分化癌の1例2010
- Author(s)
  打波宇
- Journal Title
  
  日消外会誌
  
  Volume: 43 Pages: 166-171
- NAID
  110007539270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591618
[Journal Article] 急速な転帰をたどった下部胆管原発の未分化癌の1例2010
- Author(s)
  打波宇、阿部ゆき、工藤和大、久米真、南條博、山本雄造
- Journal Title
  
  日消外会誌 43
  
  Pages: 166-171
- NAID
  110007539270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591618
[Journal Article] Change in the fatty acid composition of the liver with the administration of n-3 poly unsaturated fatty acids and the effects on warm ischemia/reperfu-sion injury in the rat liver.2010
- Author(s)
  Iwasaki W, Kume M, Kudo K, Uchinami H, Kikuchi I, Nakagawa Y, Yoshioka M, Yamamoto Y.
- Journal Title
  
  Shock. 33
  
  Pages: 306-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591618
[Journal Article] Clinical and prognostic significance of urinary trypsin inhibitor in patients with hepatocellular carcinoma after hepatectomy.2009
- Author(s)
  Kikuchi I, Uchinami H, Nanjo H, Hashimoto M, Nakajima A, Kume M, Mencin A, Yamamoto Y.
- Journal Title
  
  Ann Surg Oncol. 10
  
  Pages: 2805-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591618
[Journal Article] Implication of protein kinase A for a hepato-protective mechanism of milrinone pretreatment.2009
- Author(s)
  Satoh K, Kume M, Abe Y, Uchinami H, Yakubouski S, Takahashi T, Sato T, Yamamoto Y
- Journal Title
  
  J Surg Res 155
  
  Pages: 32-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591618
[Journal Article] Gene expression profiles during hepatic stellate cell activation in culture and in vivo2007
- Author(s)
  De minicis S, Seki E, Uchinami H, 他
- Journal Title
  
  Gastroenterology 132(5)
  
  Pages: 1937-1946
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591497
[Journal Article] The forkhead transcription factor FoxO1 regulates proliferation and transdifferentiation of hepatic stellate cells2007
- Author(s)
  Adachi M, Osawa Y, Uchinami H, 他
- Journal Title
  
  Gastroenterology 132(4)
  
  Pages: 1434-1446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591497
[Journal Article] Loss of MMP13 attenuates murine hepatic injury and fibrosis during cholestasis2006
- Author(s)
  打波宇
- Journal Title
  
  Hepatology 44/2
  
  Pages: 420-429
- Data Source
  KAKENHI-PROJECT-18591497
[Journal Article] Loss of MMP13 attenuates murine hepatic injury and fibrosis during cholestasis2006
- Author(s)
  Uchinami, H.
- Journal Title
  
  Hepatology 44(2)
  
  Pages: 420-429
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591497
[Journal Article] Loss of MMP13 attenuates murine hepatic injury and fibrosis during cholestasis2006
- Author(s)
  Uchinami H
- Journal Title
  
  Hepatology 44(2)
  
  Pages: 420-429
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591497
[Presentation] 当科における肝胆膵癌に対する切除成績の推移2022
- Author(s)
  打波宇、飯田正毅、渡辺剛、中川康彦、阿部ゆき、熊谷健太、佐藤公彦、山本雄造
- Organizer
  第３４回秋田県肝胆膵癌研究会
- Data Source
  KAKENHI-PROJECT-20K09072
[Presentation] 当科における肝胆膵癌に対する切除成績の推移2021
- Author(s)
  打波宇、飯田正毅、渡辺剛、中川康彦、阿部ゆき、熊谷健太、佐藤公彦、山本雄造
- Organizer
  第３４回秋田県肝胆膵癌研究会
- Data Source
  KAKENHI-PROJECT-20K09072
[Presentation] 興味深い転移形態を示した胆嚢腺扁平上皮癌の1剖検例2013
- Author(s)
  阿部ゆき、打波　宇、山本雄造
- Organizer
  第25回日本肝胆膵外科学会学術集会
- Place of Presentation
  栃木
- Data Source
  KAKENHI-PROJECT-23591979
[Presentation] 術後早期の膵空腸吻合部CT所見とドレーン排液アミラーゼ値からみた膵液瘻の転帰予測2013
- Author(s)
  打波　宇、吉岡政人、渡辺　剛、阿部ゆき、高橋智和、山本雄造
- Organizer
  第68回日本消化器外科学会総会
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-23591979
[Presentation] 門脈内急速投与によるオリゴヌクレオチド肝導入方法の確立2013
- Author(s)
  渡辺　剛、打波　宇、吉岡政人、阿部ゆき、山本雄造
- Organizer
  第113回日本外科学会的学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591979
[Presentation] 胆管細胞癌切除例からみたリンパ節郭清の意義と補助化学療法の効果2013
- Author(s)
  打波　宇
- Organizer
  第25回日本肝胆膵外科学会・学術集会
- Place of Presentation
  栃木
- Data Source
  KAKENHI-PROJECT-23591979
[Presentation] 膵頭十二指腸切除後膵液瘻の重症化予測とその対策2013
- Author(s)
  打波　宇、吉岡政人、渡辺　剛、阿部ゆき、高橋智和、高橋香奈、安藤秀明、山本雄造
- Organizer
  第113回日本外科学会的学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591979
[Presentation] 胆管細胞癌の治療成績-胆管細胞癌切除例からみたリンパ節郭清の意義と補助化学療法の効果2013
- Author(s)
  打波宇、吉岡政人、渡辺剛、阿部ゆき、山本雄造
- Organizer
  第25回日本肝胆膵外科学会学術集会
- Place of Presentation
  栃木
- Data Source
  KAKENHI-PROJECT-23591979
[Presentation] 胆管細胞癌の治療成績胆管細胞癌切除例からみたリンパ節郭清の意義と補助化学療法の効果2013
- Author(s)
  打波　宇、吉岡政人、渡辺　剛、阿部ゆき、山本雄造
- Organizer
  第25回日本肝胆膵外科学会学術集会
- Place of Presentation
  栃木
- Data Source
  KAKENHI-PROJECT-23591979
[Presentation] 糖尿病は肝細胞癌切除症例の予後に影響をおよぼすか?2013
- Author(s)
  渡辺　剛、打波　宇、吉岡政人、阿部ゆき、山本雄造
- Organizer
  第68回日本消化器外科学会総会
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-23591979
[Presentation] 中下部胆管癌切除症例の再発形式からみた至適リンパ節郭清範囲の検討2012
- Author(s)
  打波宇、吉岡政人、渡辺剛、阿部ゆき、高橋智和、安藤秀明、山本雄造
- Organizer
  第112回日本外科学会定期学術首魁
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23591979
[Presentation] 肝内胆管癌切除例からみた治療戦略の検討2012
- Author(s)
  打波宇、渡辺剛、吉岡政人、阿部ゆき、高橋智和、安藤秀明、山本雄造
- Organizer
  第67回日本消化器外科学会総会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-23591979
[Presentation] 右側肝円索を伴った肝内胆管癌に対する肝左3区域切除2012
- Author(s)
  打波宇、阿部ゆき、渡辺剛、吉岡政人、山本雄造
- Organizer
  第24回日本肝胆膵外科学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23591979
[Presentation] 肝虚血再灌流障害に対しNrf2は保護的に働く2012
- Author(s)
  工藤和大、打波宇、山本雄造
- Organizer
  第67回日本消化器外科学会総会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-23591979
[Presentation] 肝胆膵領域癌術後のゲムシタビン補助化学療法において肝切除による薬剤忍容性の変化2009
- Author(s)
  久米真、打波宇, 他
- Organizer
  第64回日本消化器外科学会総会
- Place of Presentation
  大阪国際会議場(大阪府)
- Data Source
  KAKENHI-PROJECT-20591618
[Presentation] 血栓形成が危惧される門脈再建時における低用量ヘパリン持続門注の有用性2007
- Author(s)
  打波宇、他
- Organizer
  第62回日本消化器外科学会定期学術総会
- Place of Presentation
  東京
- Year and Date
  2007-07-19
- Data Source
  KAKENHI-PROJECT-19659335

1. YAMAMOTO Yuzo (70281730)

# of Collaborated Projects: 4 results

# of Collaborated Products: 27 results
2. KUME Makoto (00372326)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. IIDA Masatake (90372325)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 南條博 (70250892)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. GOTO Toru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YOSHIOKA Masato

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. WATANABE Go

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. IWASAKI Wataru

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. KIKUCHI Isao

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. SATO Kohei

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. NAKAGAWA Yasuhiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. KUDOH Kazuhiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

UCHINAMI Hiroshi 打波 宇

Research Projects

Research Products

Co-Researchers

Elucidation of Reg expression control mechanism as a novel regulatory factor of liver regeneration

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

An analysis of intrahepatic lymphatic invasion in the patient with intrahepatic cholangiocarcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Stress tolerance of the cell induced by a sonochemical preconditioning using ultrasound

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of liver resection on the pharmacodynamics of gemcitabine hydrohloride

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ERストレスと蛋白合成品質管理からみた術後肝再生に関する研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Modulation of intracellular signal pathway for preventing liver damage after extended hepatectomyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 99mTc-GSA scintigraphy for assessing the functional volume ratio of the future liver remnant in the routine practice of liver resection.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reg3 and Reg3 expressions followed by JAK2/STAT3 activation play a pivotal role in the acceleration of liver hypertrophy in a rat ALPPS Model.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nrf2 activation protects the liver from ischemia-reperfusion injury in mice2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognosis analysis of sarcomatous intrahepatic cholangiocarcinoma from a view of the literature2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nrf2 activation protects the liver from ischemia/reperfusion injury in mice2014

Author(s)

Journal Title

Data Source

[Journal Article] Diffusion-weighted MRI for differential diagnosis in gallbladder lesions with special reference to ADC cut-off value2013

Author(s)

Journal Title

Data Source

[Journal Article] Diffusion-Weighted MRI for differential diagnosis in gallbladder lesions with special reference to ADC cut-off value2013

Author(s)

Journal Title

Data Source

[Journal Article] Transfection of naked nuclear factor-kB decoy oligodeoxynucleotides into liver by rapid portal vein infusion in rats : its effect on ischemia-reperfusion injury of liver2012

Author(s)

Journal Title

Data Source

[Journal Article] Liver epithelial cells proliferate under hypoxia and protect the liver from ischemic injury via expression of HIF-1 alpha target genes2012

Author(s)

Journal Title

Data Source

UCHINAMI Hiroshi 打波宇