Oishi Hajime 大石元

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OISHI Hajime 大石元

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Researcher Number	40401088
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立国際医療センター, 医長
Affiliation (based on the past Project Information) *help	2013 – 2014: 独立行政法人国立国際医療研究センター, その他部局等, その他 2011 – 2012: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Obstetrics and gynecology
Keywords	Principal Investigator ステロイド合成 / LKB1 / 顆粒膜細胞 / 卵巣 / SIRT3 / AMPK / 卵巣顆粒膜細胞 / 性ステロイド合成 / 卵胞発育 / FOXL2 / 生殖医学

The functional analysis of LKB1-AMPK system in the estrogen responsive organsPrincipal Investigator
- Principal Investigator
  
  HAJIME Oishi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Research Institute, International Medical Center of Japan
The analysis of physiological function of FOXL2 in human ovary.Principal Investigator
- Principal Investigator
  
  OISHI Hajime
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokyo

All 2014 2013 2012 2011 Other

All Journal Article Presentation Book Other

[Book] 診断と治療: 更年期における身体的・心理的・内分泌的変化2014
- Author(s)
  大石　元
- Total Pages
  5
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-25861475
[Book] 生殖医療ポケットマニュアル2014
- Author(s)
  大石　元,　矢野　晢
- Total Pages
  6
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-25861475
[Book] 3. 今日からできるホルモン補充療法―HRT実践マニュアル（水沼英樹　編著）V. 施行中の検査とトラブルの対応 2.出血時の対応．2013
- Author(s)
  大石　元，矢野　哲
- Total Pages
  5
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-25861475
[Book] 機能性食品素材のためのヒト評価（山本哲郎　監修）第11章更年期序論.2013
- Author(s)
  大石　元
- Total Pages
  6
- Publisher
  JMC出版
- Data Source
  KAKENHI-PROJECT-25861475
[Book] HRTの禁忌症例と慎重投与症例ホルモン補充療法ガイドライン2012年度版?改訂版を読み解く、臨床婦人科産科2012
- Author(s)
  大石元,矢野哲
- Data Source
  KAKENHI-PROJECT-23791815
[Book] 34.子宮筋腫;36.性交痛;102.運動療法更年期・老年期外来ベストプラクティス?誰もが知りたい104例の治療指針(神崎秀陽監修)2011
- Author(s)
  大石元
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23791815
[Journal Article] 術前診断が困難であった尿膜管腫瘍の１例2013
- Author(s)
  宮本雄一郎，平池修，長阪一憲，大石　元，甲賀かをり，藤本晃久，大須賀　穣，矢野　哲，上妻志朗，武谷雄二．
- Journal Title
  
  日本産科婦人科内視鏡学会雑誌
  
  Volume: 29(1) Pages: 69-73
- NAID
  130003395845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861475
[Journal Article] Spontaneous cessation and recurrence of massive uterine bleeding can occur in uterine artery2013
- Author(s)
  Hajime Oishi
- Journal Title
  
  J Obstet Gynaecol Res.
  
  Volume: 39(2) Issue: 2 Pages: 598-602
- DOI
  10.1111/j.1447-0756.2012.01993.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791815, KAKENHI-PROJECT-24592505
[Journal Article] Spontaneous cessation and recurrence of massive uterine bleeding can occur in uterine arterypseudoaneurysm after laparoscopicallyassisted myomectomy2013
- Author(s)
  Oishi H, Wada-Hiraike O, Osuga Y, Yano T, Kozuma S, Taketani Y
- Journal Title
  
  J Obstet Gynaecol Res
  
  Volume: 39(2) Pages: 598-602
- Data Source
  KAKENHI-PROJECT-23791815
[Journal Article] The human gonadotropin-inhibitory hormone ortholog RFamide-related peptide-3 suppresses gonadotropin-induced progesterone production in human granulosa cells.2012
- Author(s)
  H. Oishi, C. Klausen, G.E. Bentley, T. Osugi, K. Tsutsui, C.B. Gilks, T. Yano, P.C.K. Leung.
- Journal Title
  
  Endocrinology
  
  Volume: 153 Issue: 7 Pages: 3435-3445
- DOI
  10.1210/en.2012-1066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22227002, KAKENHI-PROJECT-23791815
[Journal Article] 治療に難渋したUAE後合併症の2例2012
- Author(s)
  左時江、今田信哉、大石元、甲賀かをり、平池修、亀井良政、大須賀穣、上妻志郎、武谷雄二
- Journal Title
  
  東京産科婦人科学会会誌
  
  Volume: 61(1) Pages: 115-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791815
[Journal Article] 当科における過去5年間の腹腔鏡下手術に伴う合併症の検討2012
- Author(s)
  宮下真理子,原田美由紀,大石元,藤本晃久,大須賀穣,矢野哲
- Journal Title
  
  武谷雄二関東連合産科婦人科学会誌
  
  Volume: 49 Pages: 19-23
- NAID
  40019294063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791815
[Journal Article] ヒト顆粒膜細胞におけるGnIHの生理作用(研究フロンティア:平成23年度学術奨励賞受賞論文)2012
- Author(s)
  大石元,矢野哲,武谷雄二,筒井和義
- Journal Title
  
  George E Bentley, Peter CK Leung. 日本生殖内分泌学会雑誌
  
  Volume: 17 Pages: 21-25
- Data Source
  KAKENHI-PROJECT-23791815
[Journal Article] Resveratrol promotes expression of SIRT1 and StAR in rat ovarian granulosa cells: an implicative role of SIRT1 in the ovary2012
- Author(s)
  Morita Y, Wada-Hiraike O, Yano T, Shirane A, Hirano M, Hiraike H, Koyama S, Oishi H, Yoshino O, Miyamoto Y, Sone K, Oda K, Nakagawa S, Tsutsui K,Taketani Y
- Journal Title
  
  Reprod Biol Endocrinol
  
  Volume: 23 Pages: 10-14
- Data Source
  KAKENHI-PROJECT-23791815
[Journal Article] The human gonadotropin-inhibitory hormone ortholog RFamide-related peptide-3 suppresses gonadotropin-induced progesterone production in human granulosa cells2012
- Author(s)
  Oishi H, Klausen C, Bentley GE, Osugi T, Tsutsui K, Gilks CB, Yano T, Leung PC
- Journal Title
  
  Endocrinology
  
  Volume: 153(7) Pages: 3435-45
- Data Source
  KAKENHI-PROJECT-23791815
[Journal Article] Regulation of SIRT1 determines initial step of endometrial receptivity by controlling E-cadherin expression2012
- Author(s)
  Shirane A, Wada-Hiraike O, Tanikawa M, Seiki T, Hiraike H, Miyamoto Y, Sone K, Hirano M, Oishi H, Oda K, Kawana K, Nakagawa S, Osuga Y, Fujii T, Yano T, Kozuma S, Taketani Y
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 424(3) Pages: 604-10
- Data Source
  KAKENHI-PROJECT-23791815
[Presentation] 抗老化分子SIRT1活性化物質レスベラトロールは細胞接着分子E-cadherinの発現を制御し胚の子宮内膜接着能を向上させる2012
- Author(s)
  白根晃,平池修,谷川道洋,平野茉来,森田吉洋,櫻橋彩子,傳厚掬,大石元,織田克利,川名敬,藤井知行,矢野哲,上妻志郎
- Organizer
  第17回日本生殖内分泌学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791815
[Presentation] The effect of combined raloxifene and connjugated estrogen on bone metabolism, endometrial safety, and coagulation profile in postmenopausal osteoporotic women2012
- Author(s)
  Oishi H, Yano T, Hiraike O, Hirano M, Kozuma S, Taketani Y
- Organizer
  Endo 2012
- Place of Presentation
  Houston, USA
- Data Source
  KAKENHI-PROJECT-23791815
[Presentation] ヒト卵巣顆粒膜細胞におけるGnIHの生理作用2012
- Author(s)
  大石元,矢野哲,武谷雄二,筒井和義,Bentley George E., Leung Peter C.K
- Organizer
  第16回日本生殖内分泌学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791815
[Presentation] A case of uterine artery pseudoaneurysm after laparoscopically assisted myomectomy2011
- Author(s)
  Hajime Oishi, Osamu Hiraike, Shinya Imada, Makoto Takeuchi, Yutaka Osuga, Tetsu Yano, Yuji Taketani
- Organizer
  the 6th AAGL International Congress in conjunction with the 12th APAGE Annual Congress
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23791815
[Presentation] A case of uterine artery pseudoaneurysm after laparoscopically-assisted myomectomy2011
- Author(s)
  Oishi H, Hiraike O, Imada S, Takeuchi M, Osuga Y, Yano T, Taketani Y
- Organizer
  6th AAGL International Congress onMinimally Invasive Gynecology inconjunction with 12th APAGE AnnualCongress
- Place of Presentation
  Osaka, Japan
- Data Source
  KAKENHI-PROJECT-23791815
[Presentation] 閉経期女性に対する塩酸ラロキシフェンおよび結合型エストロゲンの併用療法と低用量HRTとの骨代謝に及ぼす効果についての比較2011
- Author(s)
  大石元,松山玲子,中澤学,平池修,大須賀穣,久具宏司,矢野哲,武谷雄二
- Organizer
  第26回日本女性医学学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23791815
[Presentation] 閉経期女性に対する塩酸ラロキシフェンおよび結合型エストロゲンの併用療法と低用量HRTとの骨代謝に及ぼす効果についての比較2011
- Author(s)
  大石　元、松山玲子、中澤　学、平池　修、大須賀　穣、久具宏司、矢野　哲、武谷雄二
- Organizer
  第26回女性医学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23791815
[Presentation] Human GnIH regulates steroidogenesis in human granulosa cell2011
- Author(s)
  Hajime Oishi, Tetsu Yano, Yuji Taketani, Kazuyoshi Tsutsui, George E. Bentley, Peter C.K. Leung
- Organizer
  第63回日本産科婦人科学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23791815
[Presentation] ヒト卵巣顆粒膜細胞におけるGnIH の生理作用2011
- Author(s)
  大石元、矢野哲、武谷雄二、筒井和義、George E. Bentley, Peter CK Leung
- Organizer
  第16回生殖内分泌学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791815
[Presentation] 凍結融解胚移植例と新鮮胚移植例の妊娠初期の血清hCG値推移の比較検討
- Author(s)
  吉新明日香，原田美由紀，大津　洋，藤本晃久，大石　元，平田哲也，堤亮，大井なぎさ，甲賀かをり，平池修，大須賀穣，藤井知行
- Organizer
  第58回日本生殖医学会学術講演会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25861475
[Presentation] The effect of combined raloxifene and connjugated estrogen on bone metabolism, endometrial safety, and coagulation profile in postmenopausal osteoporotic women.
- Author(s)
  Hajime Oishi
- Organizer
  ENDO2012
- Place of Presentation
  Houston, U.S.A.
- Data Source
  KAKENHI-PROJECT-23791815
[Presentation] 2. Effect of the combination therapy with conjugated estrogens and raloxifene on bone metabolism, endometrial safety, and coagulation profile in postmenopausal women.
- Author(s)
  Hajime Oishi, Osamu Hiraike-Wada, Manabu Nakazawa, Miki Tanaka, Ayako Sakurabashi, Mana Hirano, Akira Shirane, Yoshihiro Morita, Miyuki Harada, Maya Takamoto, Shiqing Zhang, Misao Nakanishi, Miyuki Sadatsuki, Koji Kugu, Yutaka Osuga, Tetsu Yano.
- Organizer
  The 5th Scientific Meeting of the Asia Pacific Menopause Federation (APMF).
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25861475
[Presentation] 不妊症患者における子宮内膜ポリープの治療とその効果に関する検討
- Author(s)
  大石　元
- Organizer
  第57回日本生殖医学会学術講演会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-23791815
[Presentation] セプラフィルムの安定的な搬入方法; 腹腔鏡用ガーゼを用いた簡単な搬入方法および貼付の工夫
- Author(s)
  大石　元、大西賢人、中西美紗緒、中西恵美、諸宇ヒブン、郷田朋子、桝谷法生、張士青、高本真弥、定月みゆき、矢野　哲
- Organizer
  日本産科婦人科内視鏡学会
- Place of Presentation
  鹿児島
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25861475
[Presentation] 4. 家族性卵巣機能不全原因遺伝子FOXL2はエストロゲンレセプター（ER）βの転写活性化能を抑制する．
- Author(s)
  平野茉来，平池　修，白根　晃，櫻橋彩子，傅厚菊，磯野渉，大石　元，織田克利，川名敬，矢野哲，大須賀穣，藤井知行
- Organizer
  第18回日本生殖内分泌学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25861475
[]

1. OSUGI Tomohiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 筒井和義

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. BENTLEY George

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Oishi Hajime 大石 元

OISHI Hajime 大石 元

Research Projects

Research Products

Co-Researchers

The functional analysis of LKB1-AMPK system in the estrogen responsive organsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The analysis of physiological function of FOXL2 in human ovary.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 診断と治療: 更年期における身体的・心理的・内分泌的変化2014

Author(s)

Total Pages

Publisher

Data Source

[Book] 生殖医療ポケットマニュアル2014

Author(s)

Total Pages

Publisher

Data Source

[Book] 3. 今日からできるホルモン補充療法―HRT実践マニュアル（水沼英樹 編著）V. 施行中の検査とトラブルの対応 2.出血時の対応．2013

Author(s)

Total Pages

Publisher

Data Source

[Book] 機能性食品素材のためのヒト評価（山本哲郎 監修）第11章更年期序論.2013

Author(s)

Total Pages

Publisher

Data Source

[Book] HRTの禁忌症例と慎重投与症例ホルモン補充療法ガイドライン2012年度版?改訂版を読み解く、臨床婦人科産科2012

Author(s)

Data Source

[Book] 34.子宮筋腫;36.性交痛;102.運動療法更年期・老年期外来ベストプラクティス?誰もが知りたい104例の治療指針(神崎秀陽監修)2011

Author(s)

Publisher

Data Source

[Journal Article] 術前診断が困難であった尿膜管腫瘍の１例2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Spontaneous cessation and recurrence of massive uterine bleeding can occur in uterine artery2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Spontaneous cessation and recurrence of massive uterine bleeding can occur in uterine arterypseudoaneurysm after laparoscopicallyassisted myomectomy2013

Author(s)

Journal Title

Data Source

[Journal Article] The human gonadotropin-inhibitory hormone ortholog RFamide-related peptide-3 suppresses gonadotropin-induced progesterone production in human granulosa cells.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 治療に難渋したUAE後合併症の2例2012

Author(s)

Journal Title

Data Source

[Journal Article] 当科における過去5年間の腹腔鏡下手術に伴う合併症の検討2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] ヒト顆粒膜細胞におけるGnIHの生理作用(研究フロンティア:平成23年度学術奨励賞受賞論文)2012

Author(s)

Journal Title

Data Source

[Journal Article] Resveratrol promotes expression of SIRT1 and StAR in rat ovarian granulosa cells: an implicative role of SIRT1 in the ovary2012

Author(s)

Journal Title

Data Source

Oishi Hajime 大石元

OISHI Hajime 大石元

[Book] 3. 今日からできるホルモン補充療法―HRT実践マニュアル（水沼英樹　編著）V. 施行中の検査とトラブルの対応 2.出血時の対応．2013

[Book] 機能性食品素材のためのヒト評価（山本哲郎　監修）第11章更年期序論.2013