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Toba Hiroaki  鳥羽 博明

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TOBA Hiroaki  鳥羽 博明

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Researcher Number 40403745
Affiliation (Current) 2025: 徳島大学, 大学院医歯薬学研究部(医学域), 教授
Affiliation (based on the past Project Information) *help 2024: 徳島大学, 大学院医歯薬学研究部(医学域), 教授
2021 – 2023: 徳島大学, 大学院医歯薬学研究部(医学域), 准教授
2018 – 2020: 徳島大学, 大学院医歯薬学研究部(医学域), 助教
2016 – 2017: 徳島大学, 大学院医歯薬学研究部(医学系), 助教
2015: 徳島大学, 大学院医歯薬学研究部, 助教 … More
2011 – 2014: 徳島大学, ヘルスバイオサイエンス研究部, 助教
2010: The University of Tokushima, 大学院・ヘルスバイオサィエンス研究部, 助教
2008 – 2010: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教
2007: The University of Tokushima, University Medical and Dental Hospital, the medical doctor
2007: NHO Tokushima Hospital, University of Tokushima Hospital, Medical staff
2007: 徳島大学, 医学部歯学部付属病院, 医員
2007: 徳島大学, 医学部歯科部附属病院, 医員
2006: The University of Tokushima, Tokushima University Hospital, medical doctor, 医学部・歯学部附属病院, 医員
2006: 徳島大学, 医学部・歯学部附属病院, 医院 Less
Review Section/Research Field
Principal Investigator
Basic Section 55040:Respiratory surgery-related / Respiratory surgery / General surgery
Except Principal Investigator
Thoracic surgery / Respiratory surgery / Basic Section 55040:Respiratory surgery-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 55020:Digestive surgery-related / General surgery
Keywords
Principal Investigator
気管支肺胞幹細胞 / iPS細胞 / 急性肺障害 / 肺再生 / 細胞外小胞 / オルガノイド / 肺オルガノイド / p53遺伝子改変ブタ / 肺の修復・再生 / 終末細気管支障害 … More / 気道内投与 / 終末気管支障害 / 終末細気管支障害モデル / ナフタレン / 肺の再生 / ドナー / 細胞移植 / 胎仔肺 / 肺再生医療 / 移植外科学 … More
Except Principal Investigator
肺再生 / ラット / 胎生期肺組織 / 豚 / iPS細胞 / TaqMan Low Density Array / 肺癌 / 食道癌 / gene instability / 肺線維症 / ステロイド / 肺移植 / 肺の再生 / 胎仔肺移植 / 胎生期肺 / 肺組織移植 / 移植 / 癌幹細胞 / miRNA / 効果予測 / 術前化学療法 / 乳癌 / 人工知能 / コンベックス型超音波気管支鏡 / 気管・気管支浸潤 / 間葉系幹細胞 / 気管支断端瘻 / LOX阻害薬 / Lysyl oxidase(LOX) / 骨転移 / Luminal型乳癌 / 肺再生医療 / 胎児肺 / GFPマウス / ips細胞 / マウス肺移植 / 乳汁分泌 / 乳腺幹細胞 / 乳房再建 / 肺organoid / anti cancer agent related gene / metastasis related gene / lymph node metastasis / orthotopic implantation model / lung cancer / thyroid anaplastic carcinoma / esophageal cancer / 抗癌剤関連遺伝子 / 転移関連遺伝子 / リンパ節転移 / 同所性移植モデル / 甲状腺未分化癌 / carcinogenesis / pre-malignant lesion / DNA mismatch repair gene / chromate lung cancer / クロム酸塩蓄積量 / hMLH / DNA修復遺伝子蛋白 / 発癌過程 / 発癌 / 前癌病変 / DNA修復遺伝子 / クロム肺癌 / bleomycine / pulmonary fibrosis / transplantation / fetal lung / fetal lung tissue / rat / lung / lung regeneration / 組織修復 / 再生 / ブレオマイシン / 胎仔肺 / 胎児肺組織移植 / 胎仔肺組織移植 / 肺 / マウス / 肺気腫 / 胎生期肺移植 / 再生医学 / 肺の分化 / 肺の発生 / 肺組織 / 免疫抑制剤 / 肺の発生分化 / 経気道的投与 / 再生医療 / 呼吸器外科学 Less
  • Research Projects

    (19 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (25 People)
  •  薬剤耐性トリプルネガティブ乳癌に対するmiRNA-433-3p補充療法の可能性

    • Principal Investigator
      笹 聡一郎
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      The University of Tokushima
  •  iPS細胞から誘導した気管支肺胞幹細胞を用いたがん幹細胞研究

    • Principal Investigator
      河北 直也
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      The University of Tokushima
  •  人工知能を用いた食道癌の気管・気管支浸潤の診断ー診断基準の確立ー

    • Principal Investigator
      藤原 聡史
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      The University of Tokushima
  •  iPS細胞から誘導した気管支肺胞幹細胞~その性格とオルガノイドを用いた肺再生研究Principal Investigator

    • Principal Investigator
      鳥羽 博明
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      The University of Tokushima
  •  間葉系幹細胞による気管支の修復メカニズムの解明 iPS細胞による気管支断端瘻予防

    • Principal Investigator
      坂本 晋一
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      The University of Tokushima
  •  腫瘍が分泌するLOXはLuminal型乳癌の骨転移予見バイオマーカーになり得る

    • Principal Investigator
      兼松 美幸
    • Project Period (FY)
      2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      The University of Tokushima
  •  The role of p53 during airway and lung injury, repair and regeneration using TP53-mutant porcinePrincipal Investigator

    • Principal Investigator
      TOBA Hiroaki
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      The University of Tokushima
  •  Generation of functional mammary glands by mammary stem cells

    • Principal Investigator
      MORIMOTO Masami
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokushima
  •  The possibility of lung regenerative medicine using the mouse orthotopic lung transplantation.

    • Principal Investigator
      YOSHIDA Mitsuteru
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory surgery
    • Research Institution
      The University of Tokushima
  •  The attempt for lung regeneration using lung organid (lung cell and tissue transplantation)

    • Principal Investigator
      KAWAKAMI Yukikiyo
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory surgery
    • Research Institution
      The University of Tokushima
  •  Intratracheal administration of induced pluripotent stem (iPS) cells induced bronchioloalveolar stem cells (BASCs) can accelerate the repair of injured lung.Principal Investigator

    • Principal Investigator
      TOBA Hiroaki
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory surgery
    • Research Institution
      The University of Tokushima
  •  Fetal lung fragments implantation into fibrotic lung of a pig model

    • Principal Investigator
      SAKIYAMA Shoji
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory surgery
    • Research Institution
      Kochi National Hospital
      The University of Tokushima
  •  iPS細胞から誘導した気管支肺胞幹細胞を用いた肺の再生Principal Investigator

    • Principal Investigator
      鳥羽 博明
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Respiratory surgery
    • Research Institution
      The University of Tokushima
  •  Experimental examination of the pulmonary emphysema treatment with fetal lung tissues transplantation - a pig emphysema model -

    • Principal Investigator
      SAKIYAMA Shoji
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      The University of Tokushima
  •  Fetal lung cell implantation with bronchioalveolar stem cellsPrincipal Investigator

    • Principal Investigator
      TOBA Hiroaki
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokushima
  •  Implantation of fetal pig lung fragments into adult rat lung parenchyma-search for a possibility of transbronchial delivery with a bronchoscope-

    • Principal Investigator
      SAKIYAMA Shoji
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      The University of Tokushima
  •  Carcinogenesis mechanism of lung cancer of the chromate industrial workers with chromate exposure -Relationship between DNA mismatch repair hMLH gene and gene instability-

    • Principal Investigator
      KONDO Kazuya
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      The University of Tokushima
  •  A study about the anticancer agent-related gene change in the human lung cancer orthotopic implantation model

    • Principal Investigator
      MIYOSHI Takanori
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Department of Clinical Research, National Hospital Organization Tokushima National Hospital
      The University of Tokushima
  •  Lung regeneration : implantation of fetal rat lung fragments into adult rat lung with bleomycine induced fibrosis

    • Principal Investigator
      SEKIYAMA Syoji
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      The University of Tokushima

All 2016 2012 2011 2010 2009 2008 Other

All Journal Article Presentation

  • [Journal Article] Lung regeneration by fetal lung tissue implantation in a mouse pulmonary emphysema model2016

    • Author(s)
      Uyama K, Sakiyama S, Yoshida M, MD, Kenzaki K, Toba H, Kawakami Y, Okumura K, Takizawa H, Kondo K and Tangoku A.
    • Journal Title

      J Med Invest

      Volume: 63

    • NAID

      130005245852

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462127
  • [Journal Article] Implantation of fetal rat lung fragments into bleomycin-induced pulmonary fibrosis2012

    • Author(s)
      Toba H, Sakiyama S, Koichiro kenzaki, Yukikiyo kawakami, Koh Uyama, Yoshimi Bando, Akira Tangoku
    • Journal Title

      J Thorac Cardiovasc Surg

      Volume: vol.143 Pages: 1429-1435

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592062
  • [Journal Article] Implantation of fetal rat lung fragments into bleomycin-induced pulmonary fibrosis.2012

    • Author(s)
      Toba H, Sakiyama S, et al.
    • Journal Title

      J Thorac Cardiovasc Surg.

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592062
  • [Presentation] 肺の再生・修復を目的とした胎生期肺組織移植2012

    • Author(s)
      先山正二、監崎孝一郎、鳥羽博明、宇山攻、梶浦耕一郎、中川靖士、吉田光輝、川上行奎、滝沢宏光、近藤和也、丹黒章
    • Organizer
      第29回日本呼吸器外科学会総会
    • Place of Presentation
      秋田キャッスルホテル(秋田県)
    • Data Source
      KAKENHI-PROJECT-23592062
  • [Presentation] 胎仔肺移植による肺気腫自然発症モデルマウス肺修復の試み2011

    • Author(s)
      宇山攻、先山正二、鳥羽博明、吉田光輝、監崎孝一郎、丹黒章
    • Organizer
      第111回日本外科学会定期学術集会
    • Place of Presentation
      東京都
    • Data Source
      KAKENHI-PROJECT-23592062
  • [Presentation] 豚を用いた胎生期肺組織移植の実験的検討2010

    • Author(s)
      先山正二, 監崎孝一郎, 鳥羽博明, NarmisheekhKhasag, 宇山攻, 中川靖士, 滝沢宏光, 近藤和也, 丹黒章
    • Organizer
      日本外科学会雑誌(0301-4894)111巻臨増2Page648
    • Data Source
      KAKENHI-PROJECT-20591672
  • [Presentation] Sex-mismatchを用いたラット胎仔肺移植モデルのドナー細胞の組織学的検討2010

    • Author(s)
      監崎孝一郎, 先山正二, 宇山攻, 鳥羽博明, 中川靖士, 滝沢宏光, 近藤和也, 丹黒章
    • Organizer
      日本外科学会雑誌(0301-4894)111巻臨増2Page210
    • Data Source
      KAKENHI-PROJECT-20591672
  • [Presentation] 豚を用いた胎生期肺組織移植の実験的検討 ラットで得られた知見との比較を含めて2010

    • Author(s)
      先山正二, 監崎孝一郎, 鳥羽博明, NarmisheekhKhasag, 宇山攻, 中川靖士, 滝沢宏光, 近藤和也, 丹黒章
    • Organizer
      日本呼吸器外科学会雑誌(0919-0945)24巻3号Page417
    • Data Source
      KAKENHI-PROJECT-20591672
  • [Presentation] 胎仔肺組織移植により移植したグラフト内でのTTF-1発現の検討2010

    • Author(s)
      鳥羽博明
    • Organizer
      第63回日本胸部外科学会総会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Year and Date
      2010-10-25
    • Data Source
      KAKENHI-PROJECT-21791254
  • [Presentation] 呼吸器外科領域の再生医療ブレオマイシン誘導肺線維症モデルに対する胎仔肺組織移植2009

    • Author(s)
      鳥羽博明, 先山正二, 監崎孝一郎, 中川靖士, 滝沢宏光, 近藤和也, 丹黒章
    • Organizer
      日本呼吸器外科学会雑誌(0919-0945)23巻3号Page350
    • Data Source
      KAKENHI-PROJECT-20591672
  • [Presentation] ブレオマイシン誘導肺線維症モデルに対する胎仔肺組織移植2009

    • Author(s)
      鳥羽博明
    • Organizer
      第26回日本呼吸器外科学会総会
    • Place of Presentation
      北九州国際会議場(北九州市)
    • Year and Date
      2009-05-14
    • Data Source
      KAKENHI-PROJECT-21791254
  • [Presentation] GFPラットを用いた胎仔肺移植モデルのドナー組織間再融合の組織学的検討2008

    • Author(s)
      監崎孝一郎, 先山正二, 宇山攻, 松岡永, 鳥羽博明, 滝沢宏光, 広瀬由紀子, 近藤和也, 坂東良美, 丹黒章
    • Organizer
      日本外科学会雑誌(0301-4894)109巻臨増2Page213
    • Data Source
      KAKENHI-PROJECT-20591672
  • [Presentation] 胎生期肺組織移植における気道系の分化とbranchingに関する検討

    • Author(s)
      先山正二、鳥羽博明、監崎孝一郎、坪井光弘、梶浦耕一郎、中川靖士、吉田光輝、川上行奎、 滝沢宏光、近藤和也、丹黒 章
    • Organizer
      第37回日本呼吸器内視鏡学会学術集会
    • Place of Presentation
      国立京都国際会館(京都府・京都市)
    • Year and Date
      2014-04-14 – 2014-04-15
    • Data Source
      KAKENHI-PROJECT-26462127
  • 1.  KAWAKAMI Yukikiyo (00596249)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 4 results
  • 2.  SAKIYAMA Shoji (60291986)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 11 results
  • 3.  TAKIZAWA HIromitsu (90332816)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 8 results
  • 4.  YOSHIDA Mitsuteru (30403710)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 4 results
  • 5.  河北 直也 (60522266)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 6.  KONDO Kazuya (10263815)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 7.  KENZAKI Koichirou (70325265)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 8 results
  • 8.  MIYOSHI Takanori (20346612)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  MORIMOTO Masami (90563817)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  坂本 晋一 (30740675)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  KAJIURA Koichiro (60596253)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 12.  丹黒 章 (10197593)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  高嶋 美佳 (70596254)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  笹 聡一郎 (30834915)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  井上 寛章 (20792378)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  乾 友浩 (20894372)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  宇山 攻 (90437658)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 18.  坪井 光弘 (10711872)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 19.  谷原 史倫 (90754680)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  平田 真樹 (10815583)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  兼松 美幸 (90836305)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  武知 浩和 (70380102)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  藤原 聡史 (20565311)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  後藤 正和 (00437659)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  井上 聖也 (50563813)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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